CN107811706B - A Surgical Navigation System Based on Image Transmitting Optical Fiber - Google Patents
A Surgical Navigation System Based on Image Transmitting Optical Fiber Download PDFInfo
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- 239000013307 optical fiber Substances 0.000 title claims abstract description 53
- 238000003384 imaging method Methods 0.000 claims abstract description 210
- 230000005540 biological transmission Effects 0.000 claims abstract description 54
- 238000012545 processing Methods 0.000 claims abstract description 33
- 210000002966 serum Anatomy 0.000 claims abstract description 9
- 238000012360 testing method Methods 0.000 claims abstract description 9
- 230000005284 excitation Effects 0.000 claims abstract description 7
- 230000003287 optical effect Effects 0.000 claims description 36
- 238000000034 method Methods 0.000 claims description 9
- 230000000007 visual effect Effects 0.000 claims description 7
- 238000005516 engineering process Methods 0.000 claims description 4
- 238000003333 near-infrared imaging Methods 0.000 claims description 4
- 238000001228 spectrum Methods 0.000 claims description 4
- 239000011521 glass Substances 0.000 abstract description 31
- 238000000799 fluorescence microscopy Methods 0.000 abstract description 16
- 230000035945 sensitivity Effects 0.000 abstract description 11
- 238000013461 design Methods 0.000 description 17
- 210000001519 tissue Anatomy 0.000 description 6
- 238000001356 surgical procedure Methods 0.000 description 5
- 239000000126 substance Substances 0.000 description 4
- 238000003745 diagnosis Methods 0.000 description 3
- 238000009434 installation Methods 0.000 description 3
- 229910000530 Gallium indium arsenide Inorganic materials 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 238000012827 research and development Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 241000208340 Araliaceae Species 0.000 description 1
- 238000004497 NIR spectroscopy Methods 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 241000863032 Trieres Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 238000005415 bioluminescence Methods 0.000 description 1
- 230000029918 bioluminescence Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000008094 contradictory effect Effects 0.000 description 1
- 238000005034 decoration Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000005401 electroluminescence Methods 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000000877 morphologic effect Effects 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000009738 saturating Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 238000001931 thermography Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000004148 unit process Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
- A61B2034/2046—Tracking techniques
- A61B2034/2055—Optical tracking systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
- A61B2034/2046—Tracking techniques
- A61B2034/2065—Tracking using image or pattern recognition
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Robotics (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Endoscopes (AREA)
- Eye Examination Apparatus (AREA)
Abstract
The present invention discloses a kind of operation guiding system based on image transmission optical fibre.The system includes providing light source unit, object lens, imaging unit, image processing unit and the display unit of different transmitting light, object lens are arranged on safety goggles or head-wearing device, the various picture signals formed for acquiring test serum scattering, reflection or the fluorescence signal generated through excitation through different transmitting light irradiations；Imaging unit is provided on imaging unit and is passed as input interface for receiving different picture signals and is formed various images, and the biography of the output end of image transmission optical fibre and imaging unit is detachably connected as input interface；Display unit is arranged on safety goggles or head-wearing device, for showing image.The present invention can break through the limitation of the outer dimension and quantity of imaging unit itself, so that the devices such as all biggish fluorescence imaging of volume and weight is applied to intelligent glasses or head-wearing device imaging system, the functional imagings such as high sensitivity, the fluorescence imaging that multi-wavelength selects are provided.
Description
Technical field
The invention belongs to medical device fields, are related to a kind of operation guiding system based on image transmission optical fibre.
Background technique
Iconography equipment in medical surgery can help doctor to obtain the information that naked eyes can not observe directly in time,
Such as X-ray imaging is carried out in bone surgery, procedure can be observed.Near-infrared spectroscopy has been used to clinical guidance hand
Highly sensitive imaging unit can be used in art, the optical image information being capable of providing other than morphology, current optical imagery,
Image is shown and is referred on biggish screen for doctor.Also there is the design of optical operation navigation system before, by near-infrared two
On area's (850-1700nm) optical image projection to the screen of intelligent glasses or head-wearing device, to facilitate operative doctor under white light
Obtain the near-infrared image in surgical field of view.There are one but in current design, in the design of imaging unit to be difficult to solve
Certainly the problem of.
The functional signals such as fluorescence are very faint for exciting light, scattering light or reflected light, this is to imaging device
Sensitivity propose very high requirement.Improve imaging device sensitivity there are mainly two types of strategy: a. increase imaging
Unit size；B. prolonging exposure time.Imaging unit size is bigger, and imaging unit will improve the susceptibility of light；And when exposing
Between extension, be equivalent to and the receiving time of faint light increased, sensitivity will also improve, but the extension of time for exposure will lead into
As noise significantly increases, image is submerged in noise, and unique settling mode is subtracted by way of reducing imaging unit temperature
Few electronic noise.However, the solution of two above strategy requires to increase the volume of imaging device.Existing intelligent glasses
The imaging device of (safety goggles) or head-wearing device (such as wearing bracket) and intelligent glasses or head-wearing device be it is integrated, therefore,
The increase of imaging unit by make intelligent glasses or head-wearing device using extremely inconvenient.That is, intelligent glasses or wearing
The portability of device and the sensitivity of imaging are difficult to get both, this contradiction outstanding, the clinic for hindering relevant design significantly is answered
With.At present intelligent glasses or head-wearing device research and development field solve this contradictory strategy be seek it is small in size, high sensitivity at
As unit, and this imaging unit is currently to be difficult to realize, therefore this solution is unworkable.
Summary of the invention
(1) technical problems to be solved
In order to solve the above problem of the prior art, the present invention provides a kind of that intelligent glasses or head-wearing device and imaging is single
The operation guiding system based on image transmission optical fibre of member separation, imaging list can be broken through by being somebody's turn to do the operation guiding system based on image transmission optical fibre
The limitation of the outer dimension and quantity of member itself, enables the devices such as all biggish fluorescence imaging of the volume and weight of imaging unit
Successfully it is applied to intelligent glasses or head-wearing device imaging system, is capable of providing the fluorescence imaging of high sensitivity, multi-wavelength selection
Equal functional imagings.
(2) technical solution
In order to achieve the above object, the main technical schemes that the present invention uses include:
The present invention proposes a kind of operation guiding system based on image transmission optical fibre, including light source unit, object lens, imaging list
Member, image processing unit and display unit, the light source unit exist for providing different transmitting light, the object lens setting
On safety goggles or head-wearing device, scatters, reflects or generated through excitation for acquiring the test serum through different transmitting light irradiations
Fluorescence signal formed various picture signals；The imaging unit is connect by image transmission optical fibre with the object lens, is used for
It receives different picture signals and is formed various images, biography is provided on the imaging unit as input interface, the biography
As the output end of optical fiber and the biography of imaging unit are detachably connected as input interface；Described image processing unit is used for single to imaging
The image of member transmission is handled, and the display unit is arranged on safety goggles or head-wearing device, for showing through the figure
As the image after processing unit processes.
According to the present invention, the image transmission optical fibre has one or more, the imaging unit can for it is one or more at
As device, each imaging device has one or more biographies as input interface, and one passes as input interface and an image transmission optical fibre
Output end connection；
When an imaging device is only connect with an object lens, which is only received from the object lens
Picture signal is simultaneously formed various images；When multiple imaging devices are connect with the same object lens, multiple imaging dresses
It sets while receiving the picture signal from the same object lens and formed various images；When an imaging device with it is multiple
When object lens connect, this imaging device receives the various picture signals from different object lens simultaneously and is formed various
Image.
According to the present invention, the light source unit is that the light supply apparatus being independently arranged or the light source unit are integrated in operation
On lighting device；
The light source unit includes illuminating light source device and/or excitation light source device, and/or treatment light supply apparatus.
According to the present invention, the object lens include the object lens for carrying out functional imaging to test serum, and/or
The object lens include electronic imaging unit, and the electronic imaging unit includes electronic objective and and electronic objective
The image acquisition and processing mould group of connection, described image acquisition process mould group are electrically connected by data line and image processing unit.
According to the present invention, the operation guiding system based on image transmission optical fibre includes separating to the image of different-waveband
Light-dividing device；And/or
The operation guiding system based on image transmission optical fibre includes lens group and the optical filter connecting with lens group switching
Unit, the optical filter switch unit are used to provide the optical filter of different spectrum for imaging unit；And/or
The operation guiding system based on image transmission optical fibre includes achromatic lens.
According to the present invention, the light-dividing device is mounted in imaging unit, is connected to form one structure with imaging unit, or
It is arranged between imaging unit and object lens to the light-dividing device separate type, and is connect with imaging unit；And/or
The lens group and optical filter switch unit are installed in imaging unit, are connected to form one knot with imaging unit
Be arranged between imaging unit and object lens to structure or the lens group and the equal separate type of optical filter switch unit, and at
As unit connects；And/or
The achromatic lens is mounted in imaging unit, is connected to form one structure or the colour killing with imaging unit
It is arranged between imaging unit and object lens to aplanat separate type, and connect with imaging unit or the achromatic lens
It is arranged among object lens to separate type.
According to the present invention, the imaging unit is imaging device switch unit, and the imaging device switch unit is for mentioning
For different imaging devices, the imaging device switch unit is connected and is used cooperatively with the optical filter switch unit.
According to the present invention, the imaging unit includes visual light imaging device and/or near infrared imaging device.
According to the present invention, the display unit is the transmissive viewing screen being arranged on safety goggles or virtual projection eye protection eye
Mirror.
According to the present invention, described image processing unit includes image overlap processing unit, brightness adjusting unit and near-infrared
Image adds Pseudo-color technology unit.
(3) beneficial effect
The beneficial effects of the present invention are:
It is the integrated design with the imaging device of existing intelligent glasses or head-wearing device and intelligent glasses or head-wearing device
Structure is compared, and the safety goggles or head-wearing device of the operation guiding system of the invention based on image transmission optical fibre are formed with imaging unit
Separate structure is connected to biography as the biography of unit is as input interface by the output end of image transmission optical fibre, makes safety goggles or wear
Device and biography are connected as unit is formed, and breach the outer dimension of existing imaging device (imaging unit) itself and the limit of quantity
System, so that the size of imaging unit no longer restricts the development of multi-functional multifunctional intellectual glasses or head-wearing device, also more to be imaged
The design of unit intelligent glasses or head-wearing device system is laid a good foundation.To make simultaneously the volume and weight of imaging unit all compared with
The devices such as big fluorescence imaging can successfully be applied to intelligent glasses or head-wearing device imaging system, provide high sensitivity, more
The functional imagings such as the fluorescence imaging of wavelength selection greatly speed up the clinic of intelligent glasses or head-wearing device surgical navigational imaging device
Preceding research and development and clinical application process and popularization.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram for operation guiding system based on image transmission optical fibre that embodiment of the present invention provides,
Wherein, object lens are arranged on safety goggles, and display unit is arranged on safety goggles；
Fig. 2 is the structural representation for another operation guiding system based on image transmission optical fibre that embodiment of the present invention provides
Figure, wherein object lens are arranged on head-wearing device, and display unit is arranged on safety goggles.
In attached drawing: 1, light source unit；2, object lens；3, imaging unit；4, image processing unit；5, display unit；6,
Optical filter；7, image transmission optical fibre；8, lens；9, operation shadowless lamp；10, safety goggles；11, head-wearing device；12, transmission data wire.
Specific embodiment
In order to preferably explain the present invention, in order to understand, with reference to the accompanying drawing, by specific embodiment, to this hair
It is bright to be described in detail.
Fig. 1 is a kind of structural representation for operation guiding system based on image transmission optical fibre that the specific embodiment of the invention provides
Figure, wherein object lens are arranged on safety goggles, and display unit is arranged on safety goggles.Fig. 2 is specific implementation of the present invention
The structural schematic diagram for another operation guiding system based on image transmission optical fibre that mode provides, wherein object lens are arranged in head
It wears on device, display unit is arranged on safety goggles.As depicted in figs. 1 and 2, the present invention proposes a kind of based on image transmission optical fibre
Operation guiding system, including light source unit 1, object lens 2, light-dividing device, optical filter combination lens group, achromatic lens, at
As component parts such as unit 3, image processing unit 4 and display units 5.
For light source unit 1 for providing different transmitting light, different transmitting light irradiates test serum, test serum scattering,
Reflection or the fluorescence signal generated through excitation form various picture signals.Object lens can be used to acquire various picture signals.Respectively
Kind picture signal is transferred to imaging unit 3 by image transmission optical fibre 7.Imaging unit 3 can receive different picture signals and by these
Picture signal forms various images, and the various images that image processing unit 4 transmits imaging unit 3 are handled.Display unit 5
Then it is used to show through treated the image of image processing unit 4.
Specifically, light source unit 1 can provide different light sources, it can be sharp that light source unit 1, which can be illuminating light source device,
Light emitting source apparatus can be treatment light supply apparatus, can also be the group of above-mentioned two of them or two or more light supply apparatus
It closes.Light supply apparatus quantity at light source unit 1 can be one or more.It, can be with when selecting above-mentioned single light supply apparatus
Selection belongs to multiple and different light supply apparatus in a kind of light supply apparatus；When selecting the light supply apparatus of said combination form,
It can choose multiple and different light supply apparatus in above-mentioned various types of light sources device, for example, light source unit 1 can generate illumination simultaneously
Light, exciting light, treatment light and white-light illuminating light etc. are not shared the same light.The light supply apparatus of light source unit 1 can be separately provided, independent as one
Light supply apparatus, can also be integrated with operation shadowless lamp 9 (surgical lighting instrument), it is not only easy to use but also advantageous
In saving installation space.In this case, the light and the transmitting light of fluorescence imaging that operation shadowless lamp issues is not be overlapped.
Object lens 2 may be provided on safety goggles 10 (referring to Fig. 1), also can be set and (wears branch in head-wearing device 11
Frame) on (referring to fig. 2), facilitate wearing to have the medical staff of safety goggles 10 or head-wearing device 11 during surgery can be continuous, real
When collect through it is different transmitting light irradiation test serums scattering, reflection or through excitation generate fluorescence signal formed it is various
Picture signal.Object lens 2 can only include functional imaging object lens, and the picture signal of object lens acquisition is passed by image transmission optical fibre 7
It is defeated to be imaged to imaging unit 3, realize the functional imaging to test serum.
Object lens 2 can also only include electronic imaging unit, electronic imaging unit include electronic objective and with electronics object
The image acquisition and processing mould group of mirror connection, image acquisition and processing mould group are directly electrically connected with image processing unit 4 by data line,
Acquired image is transferred directly to image processing unit 4 and handled by electronic imaging unit, realizes high-resolution form
Imaging.
Object lens 2 can also include functional imaging object lens and electronic imaging unit, wherein the acquisition of functional imaging object lens
Light is transferred to imaging unit 3 and is imaged by image transmission optical fibre 7, electronic imaging unit by data line directly and image procossing list
Member 4 is electrically connected, and the two while uses, and can obtain functional imaging and high-resolution structure imaging simultaneously.
In the present embodiment, imaging unit 3 may include one or more independent imaging devices, these imaging devices
It can choose the visual light imaging device that visible light wave range is imaged, such as take into account sensitivity and Image Acquisition speed
EMCCD camera；Also the functional imaging device that near infrared band is imaged, such as the tool near infrared imaging be can choose
There is highly sensitive, high-resolution InGaAs camera；Can with the above-mentioned visual light imaging device of simultaneous selection and near-infrared at
As device.When functional imagings devices such as above-mentioned imaging device selection fluorescence imagings, highly sensitive, multi-wavelength choosing can be realized
The functional imagings such as the fluorescence imaging selected.
In this case, which type of imaging device no matter is selected, is provided with one on each independent imaging device
As input interface, a biography (separates a or multiple biographies as input interface is detachably connected with the output end of an image transmission optical fibre 7
Formula connection).When an imaging device and an object lens 2 (safety goggles or head-wearing device that are provided with object lens 2)
When connection, which only receives the various picture signals from the object lens 2 and is formed various images；When multiple
When imaging device is connect with the same object lens 2, multiple imaging devices are received from each of the same object lens 2 simultaneously
Kind picture signal and the image for being formed various different function.When an imaging device is connect with multiple object lens 2, this
Imaging device receives the various picture signals from different object lens 2 simultaneously and is formed various images.Therefore, of the invention
It can be realized the flexible choice of imaging function and be applicable in the functional imaging of a variety of different application scenes.
Certainly, imaging unit 3 of the invention is also designed to for the imaging device of above-mentioned multiple and different types being integrated into
The imaging device switch unit of one, equally can be realized the functional imagings such as visual light imaging, near infrared imaging, fluorescence imaging.
Have on the imaging device switch unit it is multiple pass as input interface, these pass as input interface can with connect an object lens list
The output end of image transmission optical fibre 7 of member 2 is detachably connected (i.e. separate type connection), can also be with pair that connect multiple object lens 2
The output end for the image transmission optical fibre 7 answered connects, and equally can be realized the flexible choice of imaging function and is applicable in a variety of different application fields
The functional imaging of scape, and occupy little space, easy to carry, using flexible.
In conclusion the present invention changes the imaging device of intelligent glasses or head-wearing device 11 and intelligent glasses or wears dress
The integrated design for setting 11 separates imaging unit 3 (imaging device) with intelligent glasses or head-wearing device 11, breaches imaging dress
The limitation of itself outer dimension and quantity is set, so that the size of imaging device no longer restricts multifunctional intellectual glasses or wears dress
11 development is set, also the design for 11 system of more imaging unit intelligent glasses or head-wearing device is laid a good foundation.This design will
The functional imagings devices such as all biggish fluorescence imaging of the volume and weight of imaging device are enabled successfully to be applied to Brilliant Eyes
11 system of mirror or head-wearing device provides the functional imagings such as high sensitivity, the fluorescence imaging that multi-wavelength selects, greatly speeds up Brilliant Eyes
The clinical application process and subsequent popularization of 11 surgical navigational imaging device of mirror or head-wearing device.
In the present invention, light-dividing device may be mounted in imaging unit 3, be connected to form one structure with imaging unit 3,
It can with separate type be arranged between imaging unit 3 and object lens, and be connect with imaging unit 3.Light-dividing device can incite somebody to action
Light beam splitting is Visible optical trains and near-infrared optical path two-way optical path, two-way optical path respectively by visual light imaging device and near-infrared at
Imaging is detected as device.Here light-dividing device preferably lower-cost spectroscope when installation, is directly installed spectroscope
In the installation sleeve being set in outside image transmission optical fibre 7.Light-dividing device is set at imaging unit 3, it can be to the figure of different-waveband
As being separated, the imaging respectively and real-time synchronization imaging of different wave length image are realized.
According to wavelength difference, different light paths will be imported from the image of object lens using spectroscope, and be equipped with to phase
Answer the image camera that wavelength sensitivity is high.The image integration of these cameras together, imaging while can be realized different-waveband.
Such as using 900nm spectroscope, imaging while can be realized simultaneously visible light and two area's fluorescence of near-infrared.
In the present invention, optical filter combination lens group includes the lens group and connect with lens group that multiple lens 8 form
The multiple optical filters 6 connect or the light transmitting sheet switch unit being connect with lens group.Wherein, optical filter switch unit is imaging unit 3
The optical filter 6 of different spectrum is provided.When imaging unit 3 selects imaging device switch unit, imaging device switch unit and filter
Mating plate switch unit is connected and is used cooperatively.
Entire optical filter combination lens group can be installed along in imaging unit 3, be connected to form one with imaging unit 3
Structure with separate type can be arranged between imaging unit 3 and object lens 2, and connect with imaging unit 3.It is glimmering when selecting
When photoimaging equipment, lens group is combined by optical filter and is realized to fluorescence imaging wave-length coverage, picture size and amplification factor
Adjustment.Further, it can be achieved by the selection of fluoroscopic imaging device and switching to visible (400-700nm), one area of near-infrared
Multi-wavelengths' image such as (700-900nm), short wavelength-NIR (2nd area 900-1700nm of near-infrared), thermal imaging (being greater than 3000nm)
Acquisition, and the image transmission optical fibre 7 thus selected should match with fluoroscopic imaging device.
May include a plurality of cameras in imaging unit of the invention, by switching to imaging device (such as EMCCD or
The different camerals such as InGaAs) and adjustable optical filter 6 combine, realize intelligent glasses or head-wearing device 11 various combination and
Multifunctional imaging.The imaging respectively to different wavelengths of light can be realized according to clinical actual demand and is imaged simultaneously, realized different
The clinical application demand of medical diagnosis on disease.Imaging unit 3 in the design can be with the intelligent glasses or head-wearing device of similar design
11 adaptations, wherein every money intelligent glasses or head-wearing device 11 can also be adapted to from a variety of different cameras, to realize imaging function
The flexible choice of energy and the functional imaging for being applicable in a variety of different application scenes.
In the present invention, achromatic lens may be mounted in imaging unit 3, be connected to form one knot with imaging unit 3
Structure with separate type can be arranged between imaging unit 3 and object lens 2, and connect with imaging unit 3 or achromatism is saturating
It is arranged among object lens 2 to mirror separate type.When selecting white light imaging device, image can be adjusted by achromatic lens
It is whole.
In the present invention, image processing unit 4 includes image overlap processing unit, brightness adjusting unit, near-infrared image
Add Pseudo-color technology unit and other image processing units.Wherein, image overlap processing unit realizes weight using characteristic point detection
Two images with overlapping region are synthesized a wide viewing angle image by the stitching algorithm of folded image.Brightness adjusting unit can mention
The brightness value of certain pixels in high two images, so that image clearly is clearly demarcated.Near-infrared image adds Pseudo-color technology unit can
Gray image is shown with customized pseudo- coloured silk, further increases image definition.Display unit can choose structure it is simple,
Display screen at low cost is realized and receives and show through above-mentioned each image processing unit treated image.
Display unit 5 is connect by transmission data wire 12 with image processing unit 4, and wireless data transmission mould can also be passed through
Block and image processing unit 4 are wirelessly connected, and wireless data transfer module can use bluetooth module, WiFi module, infrared remote control
Any one of module, 5G/4G/3G module.Display unit 5 of the invention can be transmissive viewing screen, through image processing unit 4
Treated, and image is finally shown by conduction to transmissive viewing screen.(the ginseng when transmissive viewing screen is mounted on head-wearing device 11
See Fig. 2), medical staff can see the image of surgical field of view on transmissive viewing screen in the course of surgery, provide for surgical procedure auxiliary
It helps, is brought convenience to doctor, greatly improve procedure efficiency and success rate of operation.When transmissive viewing screen is mounted on safety goggles 10
When (referring to Fig. 1), compared to transmissive viewing screen be arranged on head-wearing device 11, be more convenient medical staff directly on safety goggles 10
Observe image, convenience is higher.
(a virtual reality eye is such as selected when safety goggles 10 of the invention is selected as a kind of virtual projection safety goggles
Mirror) when, which both can be used for protective spectacles, and radiant light is avoided to damage eyes, be also used as showing
Unit 5 is shown in trier's by safety goggles 10 in a manner of virtual projection through treated the image of image processing unit 4
It is more convenient to use in the visual field.
Operation guiding system based on image transmission optical fibre of the invention can be designed to following application example:
1, more image transmission optical fibres cooperate multiphase machine simultaneously imaging
The design can cooperate multiple image cameras and different optical filters using more image transmission optical fibres simultaneously, realize to a variety of
It is acquired while different wave length optics signal.There is different characteristic spectrums in different biological tissues, to different wave length light
Absorbability and scattering power difference, cooperate the optical dye of different optics and biological characteristics, can be used for distinguishing different
Tissue, such as distinguish pathological tissue and physiological tissue.The luminescent substance of especially various principles, such as bioluminescence substance, change
Luminescent substance is learned, electroluminescence substance etc. may be used to medical domain.Usually weaker, the required camera but these shine
It is difficult to combine with intelligent glasses or head-wearing device.Also, these applications usually require while carrying out high-resolution color
The merging of the imaging modes such as optical imagery, fluorescence imaging uses.These are to be difficult to reality in intelligent glasses or head-wearing device design
Existing.In the design, the method that can be used simultaneously using a plurality of image transmission optical fibre is realized, such as optical imagery, near-infrared one
Area's fluorescence imaging (300-800nm) is synchronous with two area's fluorescence imaging (800-1700nm) of near-infrared to be implemented.Mutually independent biography
As optical fiber can be connect with the imaging unit of specific function respectively, the multi channel imaging of intelligent glasses or head-wearing device is realized.This
A little images can both be shown respectively, also be can according to need and shown in a form of picture-in-picture, or be laminated in piece image and show.
More comprehensively image information is provided for the user of intelligent glasses or head-wearing device, provides and fills for diagnosis and further treatment
The foundation divided.
2, fibrescope and electron mirror while, are imaged
On intelligent glasses or head-wearing device assemble electronics camera lens, image is back in a manner of electric signal at image
Processing and display equipment.It is equipped with one or more image transmission optical fibre of the design and corresponding simultaneously in intelligent glasses or head-wearing device
End camera lens, acquisition image information be transmitted to corresponding imaging unit along optical fiber in the form of optical signals.Imaging
The image that unit is formed also is transmitted to image procossing and display equipment.These images can both show respectively, can also be according to need
It to show in a form of picture-in-picture, or be laminated in piece image and show, the user for intelligent glasses or head-wearing device provides
More comprehensively image information provides sufficient foundation for diagnosis and further treatment.
Take into account the high-resolution imaging of the functional imaging of fibrescope and electron mirror in the design.In the intelligent glasses of the design
Or increase electronic objective on head-wearing device, functional imaging image and high-resolution morphological images are added in this way at imaging device
To be registrated overlapping, such registration image will take into account the advantage of the characteristics of high-resolution is imaged in form and functional imaging.
3, narrow band scanning is imaged
By switching different light sources, while multiple color lighting source may be implemented using two or more imaging fibers
Forming monochrome image and mixed color narrow band scanning imaging.According to different tissues to the absorption of different wavelengths of light, scattering or reflection journey
Degree is different, distinguishes to different tissues.
4, Multifunctional imaging and light exposure treatment while, are realized
While realizing functional imaging, therapeutic laser can be emitted by lighting source, carries out laser irradiation treatment
While method, imaging fiber monitoring irradiation position and assessment therapeutic effect are used.
It is to be appreciated that describing the skill simply to illustrate that of the invention to what specific embodiments of the present invention carried out above
Art route and feature, its object is to allow those skilled in the art to can understand the content of the present invention and implement it accordingly, but
The present invention is not limited to above-mentioned particular implementations.All various changes made within the scope of the claims are repaired
Decorations, should be covered by the scope of protection of the present invention.
Claims (10)
1. a kind of operation guiding system based on image transmission optical fibre, which is characterized in that including light source unit (1), object lens (2),
Imaging unit (3), image processing unit (4) and display unit (5), the light source unit (1) are used to provide different transmitting light,
The object lens (2) are arranged on safety goggles (10) or head-wearing device (11), for acquiring through different transmitting light irradiations
The various picture signals that test serum scattering, reflection or the fluorescence signal generated through excitation are formed；The imaging unit (3) passes through
Image transmission optical fibre (7) is connect with the object lens (2), for receiving different picture signals and being formed various images, institute
It states and is provided with biography on imaging unit (3) as input interface, the output end of the image transmission optical fibre (7) and the biography picture of imaging unit (3)
Input interface is detachably connected；The image that described image processing unit (4) is used to transmit imaging unit (3) is handled, institute
It states display unit (5) to be arranged on safety goggles (10) or head-wearing device (11), for showing through described image processing unit (4)
Treated image；
The image transmission optical fibre (7) has one or more, and the imaging unit (3) is for providing different imaging devices, each
Imaging device has one or more pass as input interface, an output end passed as input interface and an image transmission optical fibre (7)
Connection；
When an imaging device is only connect with an object lens (2), which is only received from the object lens (2)
Picture signal and formed various images.
2. a kind of operation guiding system based on image transmission optical fibre according to claim 1, it is characterised in that: when multiple imagings
When device is connect with the same object lens (2), multiple imaging devices receive the figure for coming from the same object lens (2) simultaneously
As signal and formed various images；When an imaging device is connect with multiple object lens (2), this imaging device is simultaneously
It receives the various picture signals from different object lens (2) and is formed various images；When multiple imaging devices with it is multiple
Object lens (2) connect when, multiple imaging devices receives respectively come from different object lens (2) various picture signals and by its
It is integrally formed various images.
3. a kind of operation guiding system based on image transmission optical fibre according to claim 2, it is characterised in that: the light source list
First (1) is that the light supply apparatus being independently arranged or the light source unit (1) are integrated on surgical lighting instrument；
The light source unit (1) includes illuminating light source device and/or excitation light source device, and/or treatment light supply apparatus.
4. a kind of operation guiding system based on image transmission optical fibre according to claim 3, it is characterised in that: the object lens list
First (2) include the object lens for carrying out functional imaging to test serum, and/or
The object lens (2) include electronic imaging unit, and the electronic imaging unit includes electronic objective and and electronic objective
The image acquisition and processing mould group of connection, described image acquisition process mould group are connected by data line and image processing unit (4).
5. a kind of operation guiding system based on image transmission optical fibre according to claim 4, it is characterised in that: described based on biography
As the operation guiding system of optical fiber includes the light-dividing device separated to the image of different-waveband；And/or
The operation guiding system based on image transmission optical fibre includes lens group and the optical filter switch unit connecting with lens group,
The optical filter switch unit is used to provide the optical filter (6) of different spectrum for imaging unit (3)；And/or
The operation guiding system based on image transmission optical fibre includes achromatic lens.
6. a kind of operation guiding system based on image transmission optical fibre according to claim 5, it is characterised in that: the light splitting dress
It sets and is mounted in imaging unit (3), set with being connected to form one structure or the light-dividing device separate type with imaging unit (3)
It sets between imaging unit (3) and object lens, and is connect with imaging unit (3)；And/or
The lens group and optical filter switch unit are installed in imaging unit (3), are connected to form one with imaging unit (3)
Be arranged in structure or the lens group and the equal separate type of optical filter switch unit imaging unit (3) and object lens (2) it
Between, and connect with imaging unit (3)；And/or
The achromatic lens is mounted in imaging unit (3), is connected to form one and structure or described is disappeared with imaging unit (3)
It is arranged between imaging unit (3) and object lens (2) to color difference lens separate type, and connect with imaging unit (3) or described
Achromatic lens separate type it is arranged among object lens (2).
7. a kind of operation guiding system based on image transmission optical fibre according to claim 5, it is characterised in that: the imaging is single
First (3) are imaging device switch unit, and the imaging device switch unit is for providing different imaging devices, the imaging dress
It sets switch unit and is connected and is used cooperatively with the optical filter switch unit.
8. a kind of operation guiding system based on image transmission optical fibre according to claim 1-7, it is characterised in that: institute
Stating imaging unit (3) includes visual light imaging device and/or near infrared imaging device.
9. a kind of operation guiding system based on image transmission optical fibre according to claim 1-7, it is characterised in that: institute
Stating display unit (5) is the transmissive viewing screen or virtual projection safety goggles being arranged on safety goggles (10).
10. a kind of operation guiding system based on image transmission optical fibre according to claim 1, it is characterised in that: described image
Processing unit (4) includes the function images such as image overlap processing unit, brightness adjusting unit and near-infrared addition Pseudo-color technology list
Member.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711205982.8A CN107811706B (en) | 2017-11-27 | 2017-11-27 | A Surgical Navigation System Based on Image Transmitting Optical Fiber |
| PCT/CN2017/115199 WO2019100449A1 (en) | 2017-11-27 | 2017-12-08 | Imaging fiber based surgical navigation system |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711205982.8A CN107811706B (en) | 2017-11-27 | 2017-11-27 | A Surgical Navigation System Based on Image Transmitting Optical Fiber |
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| Publication Number | Publication Date |
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| CN107811706A CN107811706A (en) | 2018-03-20 |
| CN107811706B true CN107811706B (en) | 2019-02-26 |
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| CN201711205982.8A Active CN107811706B (en) | 2017-11-27 | 2017-11-27 | A Surgical Navigation System Based on Image Transmitting Optical Fiber |
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| CN (1) | CN107811706B (en) |
| WO (1) | WO2019100449A1 (en) |
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| CN108833883A (en) * | 2018-08-24 | 2018-11-16 | 上海准视生物科技有限公司 | A kind of system and method for real-time generation and display 2D/3D image and image |
| CN110279392A (en) * | 2019-06-12 | 2019-09-27 | 上海健康医学院 | Fundus fluorescence imaging system and method |
| US11954785B2 (en) | 2021-12-07 | 2024-04-09 | Canon Medical Systems Corporation | Data processing method and apparatus |
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| CN103300812A (en) * | 2013-06-27 | 2013-09-18 | 中国科学院自动化研究所 | Endoscope-based multispectral video navigation system and method |
| CN106029000A (en) * | 2014-02-21 | 2016-10-12 | 阿克伦大学 | Imaging and display systems for guiding medical interventions |
| JP2017524281A (en) * | 2014-05-20 | 2017-08-24 | ユニヴァーシティ オブ ワシントン | Systems and methods for surgical visualization of mediated reality |
| CN204120989U (en) * | 2014-07-22 | 2015-01-28 | 中国科学院自动化研究所 | Inner peeping type optical molecular image-guidance system |
| CN104887321A (en) * | 2015-05-08 | 2015-09-09 | 安徽信美医学工程科技有限公司 | Portable multi-mode medical microscopy navigation device and control method thereof |
| CN106901679B (en) * | 2017-04-27 | 2019-07-09 | 苏州双威医疗器械科技有限公司 | Fluorescence microscopy endoscopic imaging system and fluorescence microscopy endoscopic imaging method |
| CN107374730A (en) * | 2017-09-06 | 2017-11-24 | 东北大学 | Optical operation navigation system |
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| CN107811706A (en) | 2018-03-20 |
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