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CN107744414A - A kind of film-coated vascular support - Google Patents

A kind of film-coated vascular support Download PDF

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Publication number
CN107744414A
CN107744414A CN201711222419.1A CN201711222419A CN107744414A CN 107744414 A CN107744414 A CN 107744414A CN 201711222419 A CN201711222419 A CN 201711222419A CN 107744414 A CN107744414 A CN 107744414A
Authority
CN
China
Prior art keywords
tube wall
film
rack body
coated vascular
vascular support
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201711222419.1A
Other languages
Chinese (zh)
Inventor
卢晔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chengdu Chuangkezhijia Technology Co Ltd
Original Assignee
Chengdu Chuangkezhijia Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chengdu Chuangkezhijia Technology Co Ltd filed Critical Chengdu Chuangkezhijia Technology Co Ltd
Priority to CN201711222419.1A priority Critical patent/CN107744414A/en
Publication of CN107744414A publication Critical patent/CN107744414A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0077Special surfaces of prostheses, e.g. for improving ingrowth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Prostheses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

The invention discloses a kind of film-coated vascular support, it is related to medical instruments field.The film-coated vascular support of the present invention includes rack body and outer membrane, rack body is in hollow tubular structure, tube wall reticulates structure, tube wall is divided into symmetrical upper tube wall and lower tube wall by the plane where the axis of hollow tubular structure, projection is respectively arranged with upper tube wall and lower tube wall, the line of the raised geometric center of the raised and lower tube wall of adjacent upper tube wall is not orthogonal to the axis of hollow tubular structure;The outer membrane is set in the rack body outer wall and wraps up at least part rack body outer wall.The film-coated vascular support of the present invention is provided with projection, support and angiogenesis relative displacement are prevented, meanwhile, the projection only forms extruding to the side of same section of blood vessel, support and the probability that reduction blood vessel is bursting at the collision while angiogenesis relative displacement are being prevented, is improving the safety in utilization of intravascular stent;The intravascular stent body outer wall is additionally provided with outer membrane, improves Clinical practicability.

Description

A kind of film-coated vascular support
Technical field
The present invention relates to medical instruments field, especially a kind of film-coated vascular support.
Background technology
Puncture shaping surgery, abbreviation PTA arts, it is under the guiding of medical imaging device, utilizes puncture needle, seal wire The foley's tube for the support for being cased with tightening is injected human vas with guide sheath, and is transported at hemadostewnosis, with the expansion of sacculus , support is also softened, and after sacculus contraction is withdrawn, the metallic support for producing plastic deformation then stays in original place, and embedded in blood vessel, Play a part of expanding blood vessel.This method is widely used in treating angiocardiopathy at present.
Clinically widely used intravascular stent mainly has bare metal stent and overlay film frame.Bare metal stent faces in entrance The effect of attracting people's attention is achieved after bed treatment.Overlay film frame generally comprises supporting construction(It can be above-mentioned bare metal stent)With Overlay film, overlay film are coated on the outside of supporting construction, and the overlay film of prior art is individual layer overlay film made of homogenous material, the overlay film Material is typically that the high molecular synthetic materials such as polyurethane, polytetrafluoroethylene (PTFE), expanded polytetrafluoroethylsealing either biological tissue derives Material.Overlay film can prevent the formation of early stage thrombus, and and can prevents growing into for the outer hyperplastic tissue of blood vessel, reduces the hair of postoperative stenosis It is raw, have a good application prospect.
The intravascular stent form of prior art have it is a variety of, most commonly rest body using shape-memory alloy wire weave Form or be welded after being cut using marmem thin plate, through axial tension, make its axial elongation, radially shorten. Its purpose is all the functions such as the radial support intensity of support to be improved and axially soft property, and support is integrally in the straight of cylinder Section, after implantable intravascular, with angiogenesis relative displacement, potential threat easily is caused to patient for support.
The content of the invention
The goal of the invention of the present invention is:For above-mentioned problem, there is provided a kind of film-coated vascular support, the blood vessel branch The rack body of frame is provided with projection, prevents support and angiogenesis relative displacement, meanwhile, the projection is only to same section of blood vessel Side forms extruding, in the probability for preventing that support is bursting at the collision with reducing blood vessel while angiogenesis relative displacement, improves blood vessel The safety in utilization of support;The intravascular stent body outer wall is additionally provided with outer membrane, improves Clinical practicability.
The technical solution adopted by the present invention is as follows:
A kind of film-coated vascular support, it includes rack body and outer membrane, and rack body is in hollow tubular structure, and tube wall reticulates knot Structure, tube wall are divided into symmetrical upper tube wall and lower tube wall, upper tube wall and down tube by the plane where the axis of hollow tubular structure Projection is respectively arranged with wall, the line of the raised geometric center of the raised and lower tube wall of adjacent upper tube wall is not orthogonal to hollow tube The axis of shape structure;The outer membrane is set in the rack body outer wall and wraps up at least part rack body outer wall.
By adopting the above-described technical solution, the upper tube wall of rack body and lower tube wall are provided with projection, projection extruding Blood vessel, increase the frictional force between blood vessel and rack body, prevent that relative position occurs between rack body and blood vessel Move, it is safe.Because the line for the geometric center that adjacent upper tube wall is raised and lower tube wall is raised is not orthogonal to hollow tubular The axis of structure, same section of blood vessel are solely subjected to that upper tube wall is raised or the extruding of lower tube wall projection one of which, i.e. one-sided compression, The probability that blood vessel is bursting at the collision can be effectively reduced, what is used is safe., can be with addition, rack body outer wall is provided with outer membrane Improve Clinical practicability.
A kind of film-coated vascular support of the present invention, the line of the raised geometric center of the raised and lower tube wall of adjacent upper tube wall Angle between the axis of hollow tubular structure is in 30 ° -75 ° or 105 ° -150 °.
Set by adopting the above-described technical solution, upper tube wall is raised with the raised asymmetry of lower tube wall, and adjacent upper tube Distance is suitable between the raised and lower tube wall projection of wall, ensures its skidproof effect.
A kind of film-coated vascular support of the present invention, the projection are in arc-shaped, and the central angle of circular arc is 135 ° -180 °.
By adopting the above-described technical solution, arc-shaped projection avoids contacting the wind that blood vessel is broken up in increase with vascularization point Danger.Central angle is too small, and raised squeezing action is too small, and skidproof effect is weak;Central angle is excessive, and it is difficult to paste completely with blood vessel Close, it is also difficult to reach satisfied skidproof effect, or even play reverse effect.
A kind of film-coated vascular support of the present invention, the diameter of the rack body are gradually reduced from centre to both ends, both ends The 75%-80% of a diameter of middle part diameter.
By adopting the above-described technical solution, middle part diameter is slightly larger, have using therapeutic purposes are reached, both ends diameter is slightly It is small, there is the injury for using transition bonding is formed between support and blood vessel, preventing edge to blood vessel.
A kind of film-coated vascular support of the present invention, the outer membrane are provided with layer 2-4.
By adopting the above-described technical solution, multilayer coating film can preferably improve the biocompatibility of overlay film frame and same Shi Zengjia covers film strength, prevents the breakage of the overlay film during overlay film frame pressure is held, discharges and bent etc..
A kind of film-coated vascular support of the present invention, its in the outer membrane in addition to the tunic of rack body outer wall one is most pressed close to He is provided with through hole on outer membrane, and gradually increases from every layer of aperture of core band outer layer.
A kind of film-coated vascular support of the present invention, the aperture of through hole is 0.1-100 μm.
By adopting the above-described technical solution, increase overlay film outer layer hole while overlay film frame channel of blood flow is ensured Rate, promote cell differentiation to promote tissue to be grown into blood vessel effectively to stick endothelial cell, accelerate aneurysm diseased region endothelium Change, to have the function that more effectively to treat aneurysmal disease.
A kind of film-coated vascular support of the present invention, the film-coated vascular support also include inner membrance, and the inner membrance is arranged at institute State the inwall at least partly covering rack body inwall of rack body;The inner membrance is combined with the outer membrane.
By adopting the above-described technical solution, inner membrance can prevent the formation of early stage thrombus, inner membrance is combined with outer membrane, is carried The stability of relative position between high inner membrance, outer membrane and rack body three.
The thickness of a kind of film-coated vascular support of the present invention, the inner membrance and the outer membrane is 0.01-0.1mm.
A kind of film-coated vascular support of the present invention, the length of the rack body are 0.5-20cm, the diameter of rack body For 1.0-8.0cm.
By adopting the above-described technical solution, by adopting the above-described technical solution, in Clinical practice, can be according to trouble The difference of person or the different sizes to intravascular stent of disease location select.
In summary, by adopting the above-described technical solution, the beneficial effects of the invention are as follows:
Film-coated vascular support provided by the invention, on the one hand it is provided with the relative upper tube wall with contacts blood and lower tube wall Projection, this projects through extruding vascular wall to increase the frictional force between intravascular stent and vascular wall, so as to prevent support and blood Relative displacement between pipe;It is asymmetric between the raised and lower tube wall projection of adjacent upper tube wall to set, ensure same section of blood vessel only Bear that upper tube wall is raised or the extruding of lower tube wall projection one of which, i.e. one-sided compression, can effectively reduce what blood vessel was bursting at the collision Probability, improve the security of Clinical practice.On the other hand, overlay film inside and outside rack body, inner membrance are advantageous to prevent early stage thrombus Formed, outer membrane can prevent growing into for the outer hyperplastic tissue of blood vessel, reduce the generation of postoperative stenosis, and outer membrane is divided into multilayer and with sky Film strength is covered in gap, increase, prevents the breakage of the overlay film during overlay film frame pressure is held, discharges and bend etc., improves clinic Practicality.
Brief description of the drawings
Examples of the present invention will be described by way of reference to the accompanying drawings, wherein:
The planar structure schematic diagram of the rack body of Fig. 1 film-coated vascular supports provided by the invention;
The dimensional structure diagram of the rack body of Fig. 2 film-coated vascular supports provided by the invention.
In figure, 1 is rack body, and 12 be upper tube wall, and 13 be lower tube wall, and 21 be raised, and 22 be raised.
Embodiment
All features disclosed in this specification, or disclosed all methods or during the step of, except mutually exclusive Feature and/or step beyond, can combine in any way.
This specification(Including any accessory claim, summary)Disclosed in any feature, unless specifically stated otherwise, Replaced by other equivalent or with similar purpose alternative features.I.e., unless specifically stated otherwise, each feature is a series of An example in equivalent or similar characteristics.
As shown in figure 1, the present embodiment provides a kind of film-coated vascular support, it includes rack body 1, during rack body 1 is in Hollow tube-like structure, tube wall is into hollow mesh structure.Rack body 1 in the present embodiment can be arbitrarily used for using of the prior art Implantable material is made, such as medical stainless steel or medical macromolecular materials.The diameter of rack body 1 is gradual from centre to both ends Reduce, the 75%-80% of a diameter of middle part diameter in both ends.Anti-skidding intravascular stent provided by the invention, the length of rack body 1 For 0.5-20cm, a diameter of 1.0-8.0cm of rack body 1.
Rack body 1 is divided into symmetrical upper tube wall 12 and lower tube wall by the plane where the axis of hollow tubular structure 13, projection 21 is provided with upper tube wall 12, projection 22, adjacent projection 21 of any two and raised 22 are provided with lower tube wall 13 The line of geometric center be not orthogonal to the axis of hollow tubular structure, the i.e. adjacent projection 21 of any two and projection 22 not It is symmetrical arranged.Preferably, the line of geometric center and the axis of hollow tubular structure of two adjacent projections 21 and projection 22 Angle between line is in 30 ° -75 ° or 105 ° -150 °.Projection 21 and projection 22 are in arc-shaped, it is preferable that the central angle of circular arc For 135 ° -180 °.
The outer wall of rack body 1 is set with outer membrane(It is not shown), the outer membrane of outer membrane at least part coated stent body.Outer membrane can To be arranged as required to layer 2-4.Wherein, in addition to one layer of outer membrane for most pressing close to the outer wall of rack body 1, it is respectively provided with other films logical Hole, and the aperture of through hole every layer of aperture from internal layer to outer layer gradually increases.Preferably, the aperture of through hole 0.1-100 μm it Between.
Rack body 1 is additionally provided with inner membrance(It is not shown), rack body 1 is set in the inner membrance, and inner membrance at least partly covers The inwall of lid support body 1, inner membrance are combined with outer membrane.Preferably, the thickness of inner membrance and outer membrane 0.01-0.1mm it Between.
The invention is not limited in foregoing embodiment.The present invention, which expands to, any in this manual to be disclosed New feature or any new combination, and disclose any new method or process the step of or any new combination.

Claims (10)

1. a kind of film-coated vascular support, it is characterised in that it includes rack body and outer membrane, and rack body is in hollow tubular knot Structure, tube wall reticulate structure, and tube wall is divided into symmetrical upper tube wall and down tube by the plane where the axis of hollow tubular structure Projection, the company of the raised geometric center of the raised and lower tube wall of adjacent upper tube wall are respectively arranged with wall, upper tube wall and lower tube wall Line is not orthogonal to the axis of hollow tubular structure;The outer membrane is set in the rack body outer wall and wraps up at least part support Body outer wall.
2. film-coated vascular support according to claim 1, it is characterised in that the raised and lower tube wall of adjacent upper tube wall is raised The line of geometric center and the axis of hollow tubular structure between angle be in 30 ° -75 ° or 105 ° -150 °.
3. film-coated vascular support according to claim 2, it is characterised in that the projection is in arc-shaped, the center of circle of circular arc Angle is 135 ° -180 °.
4. film-coated vascular support according to claim 3, it is characterised in that the diameter of the rack body is from centre to two End is gradually reduced, the 75%-80% of a diameter of middle part diameter in both ends.
5. film-coated vascular support according to claim 1, it is characterised in that the outer membrane is provided with layer 2-4.
6. film-coated vascular support according to claim 5, it is characterised in that in the outer membrane in addition to most rack body is pressed close to Through hole is provided with other outer membranes outside the tunic of wall one, and every layer of aperture gradually increases from internal layer to outer layer.
7. film-coated vascular support according to claim 6, it is characterised in that the aperture of through hole is 0.1-100 μm.
8. film-coated vascular support according to claim 7, it is characterised in that the film-coated vascular support also includes inner membrance, The inner membrance is arranged at the inwall at least partly covering rack body inwall of the rack body;The inner membrance and the outer membrane phase With reference to.
9. film-coated vascular support according to claim 8, it is characterised in that the thickness of the inner membrance and the outer membrane is 0.01-0.1mm。
10. the film-coated vascular support according to any one of claim 1-9, it is characterised in that the length of the rack body Spend for 0.5-20cm, a diameter of 1.0-8.0cm of rack body.
CN201711222419.1A 2017-11-29 2017-11-29 A kind of film-coated vascular support Pending CN107744414A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711222419.1A CN107744414A (en) 2017-11-29 2017-11-29 A kind of film-coated vascular support

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711222419.1A CN107744414A (en) 2017-11-29 2017-11-29 A kind of film-coated vascular support

Publications (1)

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CN107744414A true CN107744414A (en) 2018-03-02

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109199636A (en) * 2018-11-07 2019-01-15 北京市神经外科研究所 Overlay film compound rest

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5626602A (en) * 1992-10-12 1997-05-06 Schneider (Europe) A.G. Catheter with a vascular support
CN2571401Y (en) * 2002-08-20 2003-09-10 胡晓民 Crossless support made of nickel-titanium memory alloy for medical use
CN201123915Y (en) * 2007-10-25 2008-10-01 李楠 Medical radioactive double-membrane NiTi alloy endovascular stent
US20090118811A1 (en) * 2007-11-05 2009-05-07 Medtronic Vascular, Inc. Globe Stent
CN101496754A (en) * 2008-01-29 2009-08-05 太雄医疗器株式会社 Biodegradable double stent
CN101627933A (en) * 2008-07-17 2010-01-20 微创医疗器械(上海)有限公司 Covered stent
CN201977965U (en) * 2011-03-10 2011-09-21 南京医科大学第二附属医院 Lacrimal canaliculi stent
CN102430157A (en) * 2011-11-29 2012-05-02 武汉纺织大学 Medical scaffold with inner coating film, and preparation method for medical scaffold
CN105287048A (en) * 2014-07-03 2016-02-03 上海理工大学 Filming support

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5626602A (en) * 1992-10-12 1997-05-06 Schneider (Europe) A.G. Catheter with a vascular support
CN2571401Y (en) * 2002-08-20 2003-09-10 胡晓民 Crossless support made of nickel-titanium memory alloy for medical use
CN201123915Y (en) * 2007-10-25 2008-10-01 李楠 Medical radioactive double-membrane NiTi alloy endovascular stent
US20090118811A1 (en) * 2007-11-05 2009-05-07 Medtronic Vascular, Inc. Globe Stent
CN101496754A (en) * 2008-01-29 2009-08-05 太雄医疗器株式会社 Biodegradable double stent
CN101627933A (en) * 2008-07-17 2010-01-20 微创医疗器械(上海)有限公司 Covered stent
CN201977965U (en) * 2011-03-10 2011-09-21 南京医科大学第二附属医院 Lacrimal canaliculi stent
CN102430157A (en) * 2011-11-29 2012-05-02 武汉纺织大学 Medical scaffold with inner coating film, and preparation method for medical scaffold
CN105287048A (en) * 2014-07-03 2016-02-03 上海理工大学 Filming support

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109199636A (en) * 2018-11-07 2019-01-15 北京市神经外科研究所 Overlay film compound rest

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Application publication date: 20180302