CN107743962A - A kind of Pesticidal combination containing fourth chlorantraniliprole and chlorfenapyr and its application - Google Patents
A kind of Pesticidal combination containing fourth chlorantraniliprole and chlorfenapyr and its application Download PDFInfo
- Publication number
- CN107743962A CN107743962A CN201711210049.XA CN201711210049A CN107743962A CN 107743962 A CN107743962 A CN 107743962A CN 201711210049 A CN201711210049 A CN 201711210049A CN 107743962 A CN107743962 A CN 107743962A
- Authority
- CN
- China
- Prior art keywords
- chlorantraniliprole
- chlorfenapyr
- pesticidal combination
- agent
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000005886 Chlorantraniliprole Substances 0.000 title claims abstract description 85
- PSOVNZZNOMJUBI-UHFFFAOYSA-N chlorantraniliprole Chemical compound CNC(=O)C1=CC(Cl)=CC(C)=C1NC(=O)C1=CC(Br)=NN1C1=NC=CC=C1Cl PSOVNZZNOMJUBI-UHFFFAOYSA-N 0.000 title claims abstract description 85
- CWFOCCVIPCEQCK-UHFFFAOYSA-N chlorfenapyr Chemical compound BrC1=C(C(F)(F)F)N(COCC)C(C=2C=CC(Cl)=CC=2)=C1C#N CWFOCCVIPCEQCK-UHFFFAOYSA-N 0.000 title claims abstract description 80
- 230000000361 pesticidal effect Effects 0.000 title claims abstract description 20
- 239000000203 mixture Substances 0.000 claims abstract description 40
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 23
- 241000500437 Plutella xylostella Species 0.000 claims abstract description 19
- 241000008892 Cnaphalocrocis patnalis Species 0.000 claims abstract description 16
- 241000209094 Oryza Species 0.000 claims abstract description 12
- 235000007164 Oryza sativa Nutrition 0.000 claims abstract description 12
- 235000009566 rice Nutrition 0.000 claims abstract description 12
- 239000004480 active ingredient Substances 0.000 claims abstract description 8
- 241000255967 Helicoverpa zea Species 0.000 claims abstract description 5
- 241000256247 Spodoptera exigua Species 0.000 claims abstract description 5
- 241000426497 Chilo suppressalis Species 0.000 claims abstract description 4
- 241000409991 Mythimna separata Species 0.000 claims abstract description 4
- 241001249129 Scirpophaga incertulas Species 0.000 claims abstract description 4
- 239000003905 agrochemical Substances 0.000 claims abstract description 4
- 241000255969 Pieris brassicae Species 0.000 claims abstract description 3
- 239000004530 micro-emulsion Substances 0.000 claims abstract description 3
- 239000004562 water dispersible granule Substances 0.000 claims abstract description 3
- 239000000375 suspending agent Substances 0.000 claims description 18
- 239000004359 castor oil Substances 0.000 claims description 17
- 235000019438 castor oil Nutrition 0.000 claims description 17
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims description 17
- 229920000056 polyoxyethylene ether Polymers 0.000 claims description 17
- 229940051841 polyoxyethylene ether Drugs 0.000 claims description 17
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 claims description 15
- 239000002270 dispersing agent Substances 0.000 claims description 9
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims description 7
- 239000003995 emulsifying agent Substances 0.000 claims description 7
- 239000000080 wetting agent Substances 0.000 claims description 7
- 229920001732 Lignosulfonate Polymers 0.000 claims description 6
- 150000001875 compounds Chemical class 0.000 claims description 6
- 239000007859 condensation product Substances 0.000 claims description 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 4
- 241001272567 Hominoidea Species 0.000 claims description 4
- 239000003755 preservative agent Substances 0.000 claims description 4
- 230000002335 preservative effect Effects 0.000 claims description 4
- 229910052938 sodium sulfate Inorganic materials 0.000 claims description 4
- 235000011152 sodium sulphate Nutrition 0.000 claims description 4
- 239000003381 stabilizer Substances 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 3
- 239000002562 thickening agent Substances 0.000 claims description 3
- 230000002528 anti-freeze Effects 0.000 claims description 2
- 239000006184 cosolvent Substances 0.000 claims description 2
- 239000013530 defoamer Substances 0.000 claims description 2
- 239000007884 disintegrant Substances 0.000 claims description 2
- 239000004495 emulsifiable concentrate Substances 0.000 claims description 2
- 239000000839 emulsion Substances 0.000 claims description 2
- 239000008187 granular material Substances 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- 239000004563 wettable powder Substances 0.000 claims description 2
- 150000002191 fatty alcohols Chemical class 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 16
- 241000238631 Hexapoda Species 0.000 abstract description 12
- 230000002195 synergetic effect Effects 0.000 abstract description 11
- 239000002917 insecticide Substances 0.000 abstract description 8
- 230000000749 insecticidal effect Effects 0.000 abstract description 6
- 238000001228 spectrum Methods 0.000 abstract description 5
- 235000013311 vegetables Nutrition 0.000 abstract description 5
- 241000207199 Citrus Species 0.000 abstract description 4
- 240000008042 Zea mays Species 0.000 abstract description 4
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 abstract description 4
- 235000002017 Zea mays subsp mays Nutrition 0.000 abstract description 4
- 235000020971 citrus fruits Nutrition 0.000 abstract description 4
- 235000005822 corn Nutrition 0.000 abstract description 4
- 238000009472 formulation Methods 0.000 abstract description 3
- 230000002045 lasting effect Effects 0.000 abstract description 3
- 239000007900 aqueous suspension Substances 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 28
- -1 chlorfenapyr Compound Chemical class 0.000 description 17
- 229960001777 castor oil Drugs 0.000 description 16
- 239000003814 drug Substances 0.000 description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 15
- 229920001285 xanthan gum Polymers 0.000 description 15
- 239000004202 carbamide Substances 0.000 description 14
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 13
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 13
- 238000012360 testing method Methods 0.000 description 13
- 231100000419 toxicity Toxicity 0.000 description 13
- 230000001988 toxicity Effects 0.000 description 13
- 235000010234 sodium benzoate Nutrition 0.000 description 12
- 239000004299 sodium benzoate Substances 0.000 description 12
- 238000013329 compounding Methods 0.000 description 11
- 238000000034 method Methods 0.000 description 11
- 239000000126 substance Substances 0.000 description 11
- 239000011734 sodium Substances 0.000 description 9
- 229910052708 sodium Inorganic materials 0.000 description 9
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 8
- 238000002474 experimental method Methods 0.000 description 8
- 239000000463 material Substances 0.000 description 8
- 239000000575 pesticide Substances 0.000 description 7
- 230000002265 prevention Effects 0.000 description 7
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 6
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 6
- 239000005907 Indoxacarb Substances 0.000 description 6
- 241000607479 Yersinia pestis Species 0.000 description 6
- 230000009471 action Effects 0.000 description 6
- 239000003153 chemical reaction reagent Substances 0.000 description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 230000001018 virulence Effects 0.000 description 6
- 230000006870 function Effects 0.000 description 5
- 239000007864 aqueous solution Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 238000000605 extraction Methods 0.000 description 4
- 238000005286 illumination Methods 0.000 description 4
- VBCVPMMZEGZULK-NRFANRHFSA-N indoxacarb Chemical compound C([C@@]1(OC2)C(=O)OC)C3=CC(Cl)=CC=C3C1=NN2C(=O)N(C(=O)OC)C1=CC=C(OC(F)(F)F)C=C1 VBCVPMMZEGZULK-NRFANRHFSA-N 0.000 description 4
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 4
- 229920000053 polysorbate 80 Polymers 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 3
- 235000014113 dietary fatty acids Nutrition 0.000 description 3
- 239000000194 fatty acid Substances 0.000 description 3
- 229930195729 fatty acid Natural products 0.000 description 3
- 238000005338 heat storage Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 210000004894 snout Anatomy 0.000 description 3
- 229920001817 Agar Polymers 0.000 description 2
- 240000007124 Brassica oleracea Species 0.000 description 2
- 235000003899 Brassica oleracea var acephala Nutrition 0.000 description 2
- 235000011301 Brassica oleracea var capitata Nutrition 0.000 description 2
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 2
- 239000004255 Butylated hydroxyanisole Substances 0.000 description 2
- 241000098277 Cnaphalocrocis Species 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 2
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 description 2
- 206010033799 Paralysis Diseases 0.000 description 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 2
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 description 2
- 235000004443 Ricinus communis Nutrition 0.000 description 2
- 241000985245 Spodoptera litura Species 0.000 description 2
- WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 description 2
- 239000008272 agar Substances 0.000 description 2
- 238000012271 agricultural production Methods 0.000 description 2
- 150000004996 alkyl benzenes Chemical class 0.000 description 2
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 description 2
- 235000020661 alpha-linolenic acid Nutrition 0.000 description 2
- 150000001408 amides Chemical class 0.000 description 2
- 230000008485 antagonism Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 235000019282 butylated hydroxyanisole Nutrition 0.000 description 2
- 235000010354 butylated hydroxytoluene Nutrition 0.000 description 2
- 229920005551 calcium lignosulfonate Polymers 0.000 description 2
- RYAGRZNBULDMBW-UHFFFAOYSA-L calcium;3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Ca+2].COC1=CC=CC(CC(CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O RYAGRZNBULDMBW-UHFFFAOYSA-L 0.000 description 2
- 238000012937 correction Methods 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000007598 dipping method Methods 0.000 description 2
- 235000021186 dishes Nutrition 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000011835 investigation Methods 0.000 description 2
- 231100000636 lethal dose Toxicity 0.000 description 2
- 235000020778 linoleic acid Nutrition 0.000 description 2
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 2
- 229960004488 linolenic acid Drugs 0.000 description 2
- KQQKGWQCNNTQJW-UHFFFAOYSA-N linolenic acid Natural products CC=CCCC=CCC=CCCCCCCCC(O)=O KQQKGWQCNNTQJW-UHFFFAOYSA-N 0.000 description 2
- 239000012452 mother liquor Substances 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 239000011591 potassium Substances 0.000 description 2
- 229910052700 potassium Inorganic materials 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 238000002791 soaking Methods 0.000 description 2
- PANBYUAFMMOFOV-UHFFFAOYSA-N sodium;sulfuric acid Chemical compound [Na].OS(O)(=O)=O PANBYUAFMMOFOV-UHFFFAOYSA-N 0.000 description 2
- 239000003549 soybean oil Substances 0.000 description 2
- 235000012424 soybean oil Nutrition 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 2
- JNYAEWCLZODPBN-JGWLITMVSA-N (2r,3r,4s)-2-[(1r)-1,2-dihydroxyethyl]oxolane-3,4-diol Chemical compound OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O JNYAEWCLZODPBN-JGWLITMVSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- YSUQLAYJZDEMOT-UHFFFAOYSA-N 2-(butoxymethyl)oxirane Chemical compound CCCCOCC1CO1 YSUQLAYJZDEMOT-UHFFFAOYSA-N 0.000 description 1
- CUFXMPWHOWYNSO-UHFFFAOYSA-N 2-[(4-methylphenoxy)methyl]oxirane Chemical compound C1=CC(C)=CC=C1OCC1OC1 CUFXMPWHOWYNSO-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- PWRBCZZQRRPXAB-UHFFFAOYSA-N 3-chloropyridine Chemical compound ClC1=CC=CN=C1 PWRBCZZQRRPXAB-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- UWKVOEXRDJXLGS-UHFFFAOYSA-N C(CCCCCCCCCCCCC)C(=O)O.[K] Chemical compound C(CCCCCCCCCCCCC)C(=O)O.[K] UWKVOEXRDJXLGS-UHFFFAOYSA-N 0.000 description 1
- SJWFJTPFDYSYPD-UHFFFAOYSA-N CCCCCCCCCCCCCC[S] Chemical compound CCCCCCCCCCCCCC[S] SJWFJTPFDYSYPD-UHFFFAOYSA-N 0.000 description 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
- 241000254173 Coleoptera Species 0.000 description 1
- 241000672182 Conogethes punctiferalis Species 0.000 description 1
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 241001269238 Data Species 0.000 description 1
- 229920005682 EO-PO block copolymer Polymers 0.000 description 1
- CTKINSOISVBQLD-UHFFFAOYSA-N Glycidol Chemical compound OCC1CO1 CTKINSOISVBQLD-UHFFFAOYSA-N 0.000 description 1
- 241000258937 Hemiptera Species 0.000 description 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
- 241000255777 Lepidoptera Species 0.000 description 1
- 241001232130 Maruca testulalis Species 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 241000346285 Ostrinia furnacalis Species 0.000 description 1
- 241000488583 Panonychus ulmi Species 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 240000000528 Ricinus communis Species 0.000 description 1
- 241001253920 Ryania Species 0.000 description 1
- IYBKIXZGULMFFG-UHFFFAOYSA-L S(=O)(=O)([O-])[O-].[K+].C(CCCCCCCCCCCCC)OCCCCCCCCCCCCCC.[K+] Chemical compound S(=O)(=O)([O-])[O-].[K+].C(CCCCCCCCCCCCC)OCCCCCCCCCCCCCC.[K+] IYBKIXZGULMFFG-UHFFFAOYSA-L 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical class OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 1
- 241001414989 Thysanoptera Species 0.000 description 1
- KYUHARBNEQLZKW-UHFFFAOYSA-N [K].C(CCCCCCCCCCCC)(=O)O Chemical compound [K].C(CCCCCCCCCCCC)(=O)O KYUHARBNEQLZKW-UHFFFAOYSA-N 0.000 description 1
- QCBCOLUJVAKRFZ-UHFFFAOYSA-N [Na].C(CCCCCCCCCCCCCC)(=O)O Chemical compound [Na].C(CCCCCCCCCCCCCC)(=O)O QCBCOLUJVAKRFZ-UHFFFAOYSA-N 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000001785 acacia senegal l. willd gum Substances 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000001361 adipic acid Substances 0.000 description 1
- 235000011037 adipic acid Nutrition 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 239000004411 aluminium Substances 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 229940054066 benzamide antipsychotics Drugs 0.000 description 1
- 229940077388 benzenesulfonate Drugs 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 229920001400 block copolymer Polymers 0.000 description 1
- CZBZUDVBLSSABA-UHFFFAOYSA-N butylated hydroxyanisole Chemical compound COC1=CC=C(O)C(C(C)(C)C)=C1.COC1=CC=C(O)C=C1C(C)(C)C CZBZUDVBLSSABA-UHFFFAOYSA-N 0.000 description 1
- 229940043253 butylated hydroxyanisole Drugs 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 150000007942 carboxylates Chemical class 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 230000003915 cell function Effects 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 235000010980 cellulose Nutrition 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000013043 chemical agent Substances 0.000 description 1
- 235000015165 citric acid Nutrition 0.000 description 1
- 239000003240 coconut oil Substances 0.000 description 1
- 235000019864 coconut oil Nutrition 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 description 1
- ZHIPYMYYRWUGCU-UHFFFAOYSA-L dipotassium 1-dodecoxydodecane sulfate Chemical compound [K+].[K+].[O-]S([O-])(=O)=O.CCCCCCCCCCCCOCCCCCCCCCCCC ZHIPYMYYRWUGCU-UHFFFAOYSA-L 0.000 description 1
- IBQLPVCKRGGSCJ-UHFFFAOYSA-L disodium;1-tetradecoxytetradecane;sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O.CCCCCCCCCCCCCCOCCCCCCCCCCCCCC IBQLPVCKRGGSCJ-UHFFFAOYSA-L 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 238000006735 epoxidation reaction Methods 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- NVVZQXQBYZPMLJ-UHFFFAOYSA-N formaldehyde;naphthalene-1-sulfonic acid Chemical compound O=C.C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1 NVVZQXQBYZPMLJ-UHFFFAOYSA-N 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 125000000623 heterocyclic group Chemical group 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- HCWCAKKEBCNQJP-UHFFFAOYSA-N magnesium orthosilicate Chemical compound [Mg+2].[Mg+2].[O-][Si]([O-])([O-])[O-] HCWCAKKEBCNQJP-UHFFFAOYSA-N 0.000 description 1
- 239000000391 magnesium silicate Substances 0.000 description 1
- 229910052919 magnesium silicate Inorganic materials 0.000 description 1
- 235000019792 magnesium silicate Nutrition 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 230000002438 mitochondrial effect Effects 0.000 description 1
- 230000006705 mitochondrial oxidative phosphorylation Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000004118 muscle contraction Effects 0.000 description 1
- 125000001421 myristyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- SNMVRZFUUCLYTO-UHFFFAOYSA-N n-propyl chloride Chemical compound CCCCl SNMVRZFUUCLYTO-UHFFFAOYSA-N 0.000 description 1
- 239000005645 nematicide Substances 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 229920000191 poly(N-vinyl pyrrolidone) Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229940096992 potassium oleate Drugs 0.000 description 1
- MLICVSDCCDDWMD-KVVVOXFISA-M potassium;(z)-octadec-9-enoate Chemical compound [K+].CCCCCCCC\C=C/CCCCCCCC([O-])=O MLICVSDCCDDWMD-KVVVOXFISA-M 0.000 description 1
- VAKMIIPDYZXBEV-DPMBMXLASA-M potassium;(z,12r)-12-hydroxyoctadec-9-enoate Chemical compound [K+].CCCCCC[C@@H](O)C\C=C/CCCCCCCC([O-])=O VAKMIIPDYZXBEV-DPMBMXLASA-M 0.000 description 1
- DQFWABVCOIFBPO-UHFFFAOYSA-M potassium;tetradecyl sulfate Chemical compound [K+].CCCCCCCCCCCCCCOS([O-])(=O)=O DQFWABVCOIFBPO-UHFFFAOYSA-M 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 150000003222 pyridines Chemical class 0.000 description 1
- 150000003233 pyrroles Chemical class 0.000 description 1
- 125000000168 pyrrolyl group Chemical group 0.000 description 1
- 102000042094 ryanodine receptor (TC 1.A.3.1) family Human genes 0.000 description 1
- 108091052345 ryanodine receptor (TC 1.A.3.1) family Proteins 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- BTURAGWYSMTVOW-UHFFFAOYSA-M sodium dodecanoate Chemical compound [Na+].CCCCCCCCCCCC([O-])=O BTURAGWYSMTVOW-UHFFFAOYSA-M 0.000 description 1
- 229940082004 sodium laurate Drugs 0.000 description 1
- IJRHDFLHUATAOS-DPMBMXLASA-M sodium ricinoleate Chemical compound [Na+].CCCCCC[C@@H](O)C\C=C/CCCCCCCC([O-])=O IJRHDFLHUATAOS-DPMBMXLASA-M 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 229960000776 sodium tetradecyl sulfate Drugs 0.000 description 1
- SXHLENDCVBIJFO-UHFFFAOYSA-M sodium;2-[2-(2-dodecoxyethoxy)ethoxy]ethyl sulfate Chemical compound [Na+].CCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O SXHLENDCVBIJFO-UHFFFAOYSA-M 0.000 description 1
- UPUIQOIQVMNQAP-UHFFFAOYSA-M sodium;tetradecyl sulfate Chemical compound [Na+].CCCCCCCCCCCCCCOS([O-])(=O)=O UPUIQOIQVMNQAP-UHFFFAOYSA-M 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000001384 succinic acid Substances 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- XZZNDPSIHUTMOC-UHFFFAOYSA-N triphenyl phosphate Chemical compound C=1C=CC=CC=1OP(OC=1C=CC=CC=1)(=O)OC1=CC=CC=C1 XZZNDPSIHUTMOC-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention relates to a kind of Pesticidal combination containing fourth chlorantraniliprole and chlorfenapyr and its application, including active ingredient fourth chlorantraniliprole and active ingredient chlorfenapyr.The weight of fourth chlorantraniliprole and chlorfenapyr is than 51：1‑5.This composition can be applied to agricultural chemicals pharmacy, be configured to a variety of formulations such as the missible oil, aqueous suspension agent, microemulsion and the water dispersible granules that agriculturally allow.The present composition has relatively good effect to the rice leaf roller of the diversified economy crops such as preventing and treating rice, vegetables, corn, citrus, striped rice borer, yellow rice borer, pink rice borer, bollworm, cabbage caterpillar, diamondback moth, beet armyworm, mythimna separata etc..The present invention provides the bioactivity that a kind of insecticides improve agricultural chemicals, reduces dosage and can effectively delay the generation of the resistance of insect.Compared with unitary agent, control effect is good, lasting period length, expands insecticidal spectrum, synergistic effect is obvious.
Description
Technical field
The present invention relates to technical field of pesticide combination, more particularly to a kind of desinsection group containing fourth chlorantraniliprole and chlorfenapyr
Compound and its application.
Background technology
It is Application No. 201410190515.2, entitled《Polysubstituted pyridine base pyrazole amide and its production and use》
First Chinese patent disclose compound of formula I.National No. 048 file of pesticide standard technical committee (2017) agriculture marking-up
Name this compound Universal Chinese character entitled " fourth chlorantraniliprole ", chemical name：The bromo- N- of 3- (2- (t-Butylcarbamoyl) -4,
6- dichlorophenyls) -1- (3- chloropyridine -2- bases) -1H- pyrazoles -5- benzamides；Structural formula is：
Fourth chlorantraniliprole belongs to acid amides insecticides, is by activating the ryanodine receptor in insect muscle, causing inside
Calcium ion it is unconfined release and cause famine, prevent contraction of muscle so that insect stops rapidly feeding, there is muscle
Paralysis, vigor disappear, paralysed, until dead.To the cnaphalocrocis of the diversified economy crops such as preventing and treating rice, vegetables, corn, citrus
Snout moth's larva, striped rice borer, yellow rice borer, pink rice borer, bollworm, cabbage caterpillar, diamondback moth, beet armyworm, mythimna separata etc. have relatively good effect.
Chlorfenapyr, it is called capillary, chemical name：4- bromos -2- (4- chlorphenyls) -1- (ethoxyl methyl) -5- (trifluoros
Methyl) pyrroles's -3- nitriles；Its chemical constitution Formula II：
Chlorfenapyr belongs to new pyrrole class compound, is to be passed through by American Cyanamid Company to natural antibiotics containing pyrrole ring
Chemical constitution is transformed and is able to successfully develop a kind of new type heterocycle class desinsection, mite killing, nematicide.Its absorbability is very strong, simultaneously
Non-resistant is mutually used with other drugs.There is unique mechanism of action to insect, insect cell mitochondrial inner membrance H can be prevented
+ accumulation, ADP is not then converted to ATP, terminate cell function, ultimately result in insect death.Chlorfenapyr has stomach toxicity, tagged
And systemic action, insecticidal spectrum is wide, has good preventive effect to the various pests of Lepidoptera, Homoptera, coleoptera etc. 70, especially to vegetable
The special efficacys such as beet armyworm, diamondback moth, prodenia litura, bean-pod borer, thrips, red spider in dish insect.
It is to prevent and treat the maximally efficient means of plant pest using chemical agent in the real process of agricultural production, but
It is easiest to generate the problem that the generation of pest resistance to insecticide by chemical prevention insect.And apply for a long time single continuous high dose
One chemical insecticide, a series of problems, such as easily causing residual, the environmental pollution of medicament.Rational chemical insecticide compounding or
Mixture, which has, expands insecticidal spectrum, improves prevention effect, extends the optimum period for applying fertilizer, reduce dosage, reduce poisoning, reduce residual, prolong
The positive feature such as slow pest resistance and drug-fast generation and development, pesticide compositional or mixture are to solve the above problems most
For one of effective method.
The content of the invention
In view of this, it is necessary to for it is above-mentioned the problem of, there is provided a kind of desinsection group containing fourth chlorantraniliprole and chlorfenapyr
Compound and its application, this composition include active ingredient fourth chlorantraniliprole and active ingredient chlorfenapyr.Amide-type New-type wide-spectrum kills
The chlorfenapyr kind of worm agent fourth chlorantraniliprole and pyroles compounds, and safe efficient, quick-acting is good, lasting period length, extends Pesticide use
In the life-span, confrontation property of medicine pest controling effect is good, helps to overcome and delay the resistance to the action of a drug of insect.
The present invention uses following technical scheme：
A kind of Pesticidal combination containing fourth chlorantraniliprole and chlorfenapyr and its application, including active ingredient fourth chlorantraniliprole
With active ingredient chlorfenapyr；
The weight ratio of the fourth chlorantraniliprole and chlorfenapyr is 5-1：1-5.
Further, the percentage by weight of the weight summation of described fourth chlorantraniliprole and chlorfenapyr in the composition
For 0.01%-50%.
Further, the percentage by weight of the weight summation of described fourth chlorantraniliprole and chlorfenapyr in the composition
For 30%.
Further, the composition also includes auxiliary element, and described auxiliary element includes solvent, cosolvent, disperseed
One kind or several in agent, emulsifying agent, wetting agent, disintegrant, thickener, stabilizer, defoamer, preservative, antifreeze and carrier
Kind.
Further, described dispersant is lignosulfonates, APES, formaldehyde condensation products sulfuric acid
Salt, alkyl benzene sulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, aliphatic amine polyoxyethylene ether, polyoxyethylene carboxylate, glycerine
In fatty acid ester APEO, polyox-yethylene-polyoxypropylene block copolymer, ethylene oxide-propylene oxide block copolymer
One or two.
Further, described dispersant is lignosulfonates, APES, formaldehyde condensation products sulfuric acid
Sodium；Preferably lignosulfonates；More preferably sodium lignin sulfonate.
Further, described emulsifying agent includes enuatrol or potassium oleate, linoleic acid sodium or linoleic acid sodium, linolenic acid sodium
Or linolenic acid potassium, sodium ricinoleate or potassium ricinoleate, myristyl carboxylic acid sodium or myristyl carboxylic acid potassium, myristyl sulphur
Sour sodium or potassium tetradecyl sulfate, myristyl ether sodium sulfate or myristyl ether potassium sulfate, lauryl sodium sulfate or 12
Alkylsurfuric acid potassium, sodium laurate or dodecyl carboxylic acid potassium, sodium lauryl tri(oxyethyl) sulfate or lauryl ether potassium sulfate,
12 to tetradecyl alchohol APEO (AEO), 16 to polyoxyethylene octadecanol (peregals), coconut oil APEO,
Oleic acid polyoxyethylene, sorbitan fatty acid ester (sapn), fatty acid esters of sorbitan APEO (tween), castor
The one or more of sesame oil APEO (EL) and APG (APG).
Further, described emulsifying agent is castor oil polyoxyethylene ether (EL) and/or AEO sulfuric acid
Sodium (AES).
Further, described wetting agent is neopelex, lauryl sodium sulfate, pull open powder, alkylbenzene
One or more in sulfonate, sodium tetradecyl sulfate, spaonin powder.
Further, described wetting agent is neopelex.
Further, the thickener is xanthans, Arabic gum, hydroxylmethyl cellulose, hydroxyethyl cellulose, magnesium silicate
One or more in aluminium, polyvinyl alcohol, white carbon.
Further, the stabilizer be triphenyl phosphate, soybean oil, epoxidized soybean oil, epoxidation chloropropane, BHT,
It is BHA, citric acid, castor oil, sorb sodium alkoxide, butyl glycidyl ether, cresyl glycidyl ether, butylated hydroxy anisole, poly-
Ethylene glycol and the one or more in glycidol ether, adipic acid or succinic acid.
Further, described preservative is in sodium benzoate, D-sorbite, citric acid, 2,6 BHTs
It is a kind of.
Further, the Pesticidal combination is applied to agricultural chemicals pharmaceutical field.
Further, the Pesticidal combination can be made into emulsifiable concentrate, granule, wettable powder, water dispersible granules, micro emulsion
The formulations such as agent, suspending agent or aqueous emulsion.
Further, the composition is applied to preventing and treating for preventing and treating the diversified economies such as rice, vegetables, corn, citrus work
The rice leaf roller of thing, diamondback moth, corn borer, dichocrocis punctiferalis, prodenia litura, bollworm etc..
The beneficial effect that can be reached using the present invention program：
The present invention is acid amides insecticides and pyrrole insecticides mixture, and the fourth chlorantraniliprole of amide-type acts on ryania
Acceptor mechanism has the function that different machines from the chlorfenapyr interference insect body cell mitochondrial oxidative Phosphorylation events of pyroles
Reason, the insecticide mixture of both different mechanisms of action show notable synergistic effect, are used alone and significantly improve than single dose
To the prevention effect of insect.Two class difference insecticidal mechanisms, can mutually make up, then coordinate different adjuvants, can extend and hold
The effect phase, more preferably play drug effect.The fourth chlorantraniliprole of amide-type and the chlorfenapyr compounding of pyroles, can expand its insecticidal spectrum,
Prevention effect is improved, reduces dosage, reduces residues of pesticides, extends the Pesticide use life-span, delays the generation of pest resistance.
Embodiment
In order to better illustrate technical solution of the present invention problem to be solved, the technical scheme used and reach beneficial
Effect, it is expanded on further in conjunction with embodiment.What deserves to be explained is technical solution of the present invention is including but not limited to following
Embodiment.
Unreceipted particular technique or condition in the embodiment of the present invention, according to the technology described by document in the art or
Condition is carried out according to product description.Agents useful for same or the unreceipted production firm person of instrument, being can be by purchased in market etc.
The conventional products that approach obtains.
A kind of Pesticidal combination containing fourth chlorantraniliprole and chlorfenapyr of the present invention and its application, the Insecticidal combinations include
Fourth chlorantraniliprole and chlorfenapyr；Weight ratio is 10-1 in the composition for described fourth chlorantraniliprole and chlorfenapyr:1-10.Institute
Percentage by weight of the fourth chlorantraniliprole and chlorfenapyr weight summation stated in composition pesticide is 0.01%-50%.Adopt below
Illustrated with indoor co-toxicity test and field control effectiveness test.
Test the indoor biological activity of a fourth chlorantraniliprole and chlorfenapyr single dose and the present composition to diamondback moth larvae
Measure
Drug solution preparing：
Acetone solution active compound is first used, then is diluted with containing the 0.15% Tween 80 aqueous solution.Single dose mother liquor is made into, according to experiment
Mixture purpose, agent activity design 7 different proportionings, each single dose and often assemble than mixture according to wait ratio method setting 5
Individual series mass concentration.
Using leaf dipping method (international resistance Action Committee IRAC is proposed)：Certain density decoction to be measured, with straight peen tweezers
Fresh cabbage blade is gripped, is impregnated 10 seconds, extraction raffinate is got rid of in taking-up, and is dried at room temperature, is laid on and is previously charged into 1% agar
In the 3cm culture dishes of (3cm is thick), put 1 (culture dish 2/3 is suitable) per ware.Experiment sets chemicals treatment (the i.e. concentration of 5 concentration
Respectively 5,10,20,40,80mg/L), each handle 3 repetitions；
It is another to get rid of extraction raffinate with 0.15% Tween 80 aqueous solution soaking cabbage blade is contained, and room temperature dry after be laid on
As control in culture dish.Each culture dish access 2 age diamondback moth larvae 50, covers culture dish lid.Culture dish is placed in 25
Cultivated in ± 1 DEG C of 70%RH illumination box, illumination in 10 hours, 14 hours dark Dark-light cycles are set.After 72h, 2 are checked
Age diamondback moth larvae death condition (gently touches 2 age diamondback moth larvaes, the motionless person of body or body have been punctured into fine, soft fur pen
It is dead).Then calculate the death rate, as the control group death rate be higher than 20%, then test calcellation reform.Death rate Abbott formula
Correction, further according to log concentration --- death rate probit value analyzes (Bliss) method, obtains virulence regression equation and the lethal concentration of 50
LC50 value.The co-toxicity coefficient (CTC values) of mixture is calculated according to the abundant methods of Sun Yun.
Survey toxicity index (ATI)=(standard agent LC50/ reagent agent LC50) × 100
A percentage composition+B medicament toxicity index in theoretical toxicity index (TTI)=A medicament toxicity index × mixture × mixed
B percentage composition in agent
Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (ATI)/mixture theoretical toxicity index (TTI)] × 100
The co-toxicity coefficient of built agent：CTC >=120 are judged as synergistic effect；CTC≤80 are judged as antagonism；80<CTC<
120 are judged as summation action.
Table 1 is that reagent agent fourth chlorantraniliprole and chlorfenapyr single dose and compounding are surveyed to the indoor virulence of 2 age diamondback moth larvaes
Fixed number evidence.
Table 2 is that reagent agent fourth chlorantraniliprole and chlorfenapyr single dose and compounding are surveyed to the indoor virulence of 2 age diamondback moth larvaes
Determine result.
From table 1,2 as can be seen that fourth chlorantraniliprole and indoxacarb compound, in 5-1:In 1-5 ratio range, co-toxicity coefficient
(CTC) 120 are all higher than, synergistic function is shown to diamondback moth.Wherein fourth chlorantraniliprole and chlorfenapyr ratio are 2:When 1,
LC50 is minimum, and CTC value maximums are that synergistic effect is the most obvious.It can be seen that fourth chlorantraniliprole and indoxacarb compounding have reasonability and can
Row.
Test the indoor biological of two fourth chlorantraniliproles and chlorfenapyr single dose and the present composition to rice leaf roller larvae
Determination of activity
Drug solution preparing：
Acetone solution active compound is first used, then is diluted with containing the 0.15% Tween 80 aqueous solution.Single dose mother liquor is made into, according to experiment
Mixture purpose, agent activity design 7 different proportionings, each single dose and often assemble than mixture according to wait ratio method setting 5
Individual series mass concentration.
Using leaf dipping method (international resistance Action Committee IRAC is proposed)：Certain density decoction to be measured, with straight peen tweezers
Grip fresh rice leaf, impregnate 10 seconds, extraction raffinate is got rid of in taking-up, and is dried at room temperature, is laid on and is previously charged into 1% agar (3cm is thick)
3cm culture dishes in, put 1 (culture dish 2/3 is suitable) per ware.Experiment set 5 concentration chemicals treatment (i.e. concentration be respectively 5,
10th, 20,40,80mg/L), each handle 3 repetitions；
It is another to get rid of extraction raffinate with the fresh rice leaf of 0.15% Tween 80 aqueous solution soaking is contained, and room temperature dry after be laid on culture
As control in ware.Each culture dish access rice leaf roller larvae 50, covers culture dish lid.Culture dish is placed in 25 ± 1
Cultivated in DEG C 70%RH illumination box, illumination in 10 hours, 14 hours dark Dark-light cycles are set.After 72h, check that rice is indulged
Leaf roll snout moth's larva dead larvae situation (gently touches rice leaf roller larvae, the motionless person of body or body have been punctured into fine, soft fur pen
It is dead).Then calculate the death rate, as the control group death rate be higher than 20%, then test calcellation reform.Death rate Abbott formula
Correction, further according to log concentration --- death rate probit value analyzes (Bliss) method, obtains virulence regression equation and the lethal concentration of 50
LC50 value.The co-toxicity coefficient (CTC values) of mixture is calculated according to the abundant methods of Sun Yun.
Survey toxicity index (ATI)=(standard agent LC50/ reagent agent LC50) × 100
A percentage composition+B medicament toxicity index in theoretical toxicity index (TTI)=A medicament toxicity index × mixture × mixed
B percentage composition in agent
Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (ATI)/mixture theoretical toxicity index (TTI)] × 100
The co-toxicity coefficient of built agent：CTC >=120 are judged as synergistic effect；CTC≤80 are judged as antagonism；80<CTC<
120 are judged as summation action.
Table 3 is that reagent agent fourth chlorantraniliprole and chlorfenapyr single dose and compounding are surveyed to the indoor virulence of rice leaf roller larvae
Fixed number evidence.
Table 4 is that reagent agent fourth chlorantraniliprole and chlorfenapyr single dose and compounding are surveyed to the indoor virulence of rice leaf roller larvae
Determine result.
From table 3,4 as can be seen that fourth chlorantraniliprole and indoxacarb compound, in 5-1:In 1-5 ratio range, co-toxicity coefficient
(CTC) 150 are all higher than, synergistic function is shown to rice leaf roller larvae.Wherein fourth chlorantraniliprole and chlorfenapyr ratio
For 1:When 2, CTC value maximums are that synergistic effect is the most obvious.It can be seen that fourth chlorantraniliprole and indoxacarb are compounded to prevent and treat cnaphalocrocis
Snout moth's larva has reasonability and feasibility.
The Pesticidal combination of the present invention can be prepared into the various formulations for being suitable for agricultural production, be below specific embodiment
Percentage in formula is mass ratio.
Embodiment 1：30% fourth chlorantraniliprole chlorfenapyr suspending agent, formula combination：Fourth chlorantraniliprole 15%, chlorfenapyr
15%, neopelex 7%, castor oil polyoxyethylene ether 3%, AES5%, sodium benzoate 0.5%, urea 3%,
BHT1%, xanthans 1%, organosilicon 0.3%, water surplus.
Embodiment 2：30% fourth chlorantraniliprole chlorfenapyr suspending agent, formula combination：Fourth chlorantraniliprole 15%, chlorfenapyr
15%, neopelex 7%, castor oil polyoxyethylene ether 3%, AES5%, sodium lignin sulfonate 2%, sodium benzoate
0.5%, urea 3%, BHT1%, xanthans 1%, organosilicon 0.3%, water surplus.
Embodiment 3：30% fourth chlorantraniliprole chlorfenapyr suspending agent, formula combination：Fourth chlorantraniliprole 15%, chlorfenapyr
15%, neopelex 7%, castor oil polyoxyethylene ether 3%, AES5%, calcium lignosulfonate 2%, sodium benzoate
0.5%, urea 3%, BHT1%, xanthans 1%, organosilicon 0.3%, water surplus.
Embodiment 4：30% fourth chlorantraniliprole chlorfenapyr suspending agent, formula combination：Fourth chlorantraniliprole 15%, chlorfenapyr
15%, neopelex 7%, castor oil polyoxyethylene ether 3%, AES5%, APES 2%, benzene first
Sour sodium 0.5%, urea 3%, BHT1%, xanthans 1%, organosilicon 0.3%, water surplus.
Embodiment 5：30% fourth chlorantraniliprole chlorfenapyr suspending agent, formula combination：Fourth chlorantraniliprole 15%, chlorfenapyr
15%, neopelex 7%, castor oil polyoxyethylene ether 3%, AES5%, formaldehyde condensation products sodium sulphate 2%, benzene first
Sour sodium 0.5%, urea 3%, BHT1%, xanthans 1%, organosilicon 0.3%, water surplus.
Embodiment 6：30% fourth chlorantraniliprole suspending agent, formula combination：Fourth chlorantraniliprole 30%, neopelex
7%, castor oil polyoxyethylene ether 3%, AES5%, sodium lignin sulfonate 2%, sodium benzoate 0.5%, urea 3%, BHT1%,
Xanthans 1%, organosilicon 0.3%, water surplus.(auxiliary material is with embodiment 2)
Embodiment 7：30% chlorfenapyr suspending agent, formula combination：Chlorfenapyr 30%, neopelex 7%, castor-oil plant
Oily APEO 3%, AES5%, sodium lignin sulfonate 2%, sodium benzoate 0.5%, urea 3%, BHT1%, xanthans
1%, organosilicon 0.3%, water surplus.(auxiliary material is with embodiment 2)
Embodiment 8：30% fourth chlorantraniliprole chlorfenapyr suspending agent, formula combination：Fourth chlorantraniliprole 25%, chlorfenapyr
5%, neopelex 7%, castor oil polyoxyethylene ether 3%, AES5%, sodium lignin sulfonate 2%, sodium benzoate
0.5%, urea 3%, BHT1%, xanthans 1%, organosilicon 0.3%, water surplus.(auxiliary material is with embodiment 2)
Embodiment 9：30% fourth chlorantraniliprole chlorfenapyr suspending agent, formula combination：Fourth chlorantraniliprole 22.5%, chlorfenapyr
7.5%, neopelex 7%, castor oil polyoxyethylene ether 3%, AES5%, sodium lignin sulfonate 2%, sodium benzoate
0.5%, urea 3%, BHT1%, xanthans 1%, organosilicon 0.3%, water surplus.(auxiliary material is with embodiment 2)
Embodiment 10：30% fourth chlorantraniliprole chlorfenapyr suspending agent, formula combination：Fourth chlorantraniliprole 20%, chlorfenapyr
10%, neopelex 7%, castor oil polyoxyethylene ether 3%, AES5%, sodium lignin sulfonate 2%, sodium benzoate
0.5%, urea 3%, BHT1%, xanthans 1%, organosilicon 0.3%, water surplus.(auxiliary material is with embodiment 2)
Embodiment 11：30% fourth chlorantraniliprole chlorfenapyr suspending agent, formula combination：Fourth chlorantraniliprole 15%, chlorfenapyr
15%, neopelex 7%, castor oil polyoxyethylene ether 3%, AES5%, sodium lignin sulfonate 2%, sodium benzoate
0.5%, urea 3%, BHT1%, xanthans 1%, organosilicon 0.3%, water surplus.(with embodiment 2)
Embodiment 12：30% fourth chlorantraniliprole chlorfenapyr suspending agent, formula combination：Fourth chlorantraniliprole 10%, chlorfenapyr
20%, neopelex 7%, castor oil polyoxyethylene ether 3%, AES5%, sodium lignin sulfonate 2%, sodium benzoate
0.5%, urea 3%, BHT1%, xanthans 1%, organosilicon 0.3%, water surplus.(auxiliary material is with embodiment 2)
Embodiment 13：30% fourth chlorantraniliprole chlorfenapyr suspending agent, formula combination：Fourth chlorantraniliprole 7.5%, chlorfenapyr
22.5%, neopelex 7%, castor oil polyoxyethylene ether 3%, AES5%, sodium lignin sulfonate 2%, benzoic acid
Sodium 0.5%, urea 3%, BHT1%, xanthans 1%, organosilicon 0.3%, water surplus.(auxiliary material is with embodiment 2)
Embodiment 14：30% fourth chlorantraniliprole chlorfenapyr suspending agent, formula combination：Fourth chlorantraniliprole 5%, chlorfenapyr
25%, neopelex 7%, castor oil polyoxyethylene ether 3%, AES5%, sodium lignin sulfonate 2%, sodium benzoate
0.5%, urea 3%, BHT1%, xanthans 1%, organosilicon 0.3%, water surplus.(auxiliary material is with embodiment 2)
Test three fourth chlorantraniliproles and the experiment of chlorfenapyr complex preparation estimation of stability
Experiment is drawn：When fourth chlorantraniliprole prepares suspending agent with chlorfenapyr compounding, using wetting agent DBSA
Particle diameter can be ground less than 3 microns in sodium and emulsifying agent castor oil polyoxyethylene ether, AES, and suspensibility is more than 95% suspending agent,
But carry out (54 scholar 2) " after placing 14 in C insulating box (or water bath with thermostatic control), going for the formula using different dispersants
Place carries out the measurement result such as table 5 of certain index：
Table 5
The thermal storage stability of table 5 is shown：Using different dispersant sodium lignin sulfonates, calcium lignosulfonate, alkyl phenol
APEO, formaldehyde condensation products sodium sulphate, after heat-storage 14 days, embodiment 1 is without adding corresponding dispersant, indices
It is decreased obviously.Embodiment 1-5, in formula only the difference, emulsifying agent, wetting agent, stabilizer, preservative etc. of dispersant other into
Point just the same, so the difference of the change of active ingredient mass fraction, its main cause is not that decomposition causes, but bleed knot
Block causes.After embodiment 1, embodiment 3, embodiment 4,5 heat-storage of embodiment 14 days, there is bleed phenomenon, and under suspensibility
Drop, particle diameter increase.Embodiment 2, embodiment 3 are all lignosulfonates, but because cation is different, the dispersiveness being formulated to it
Influence still larger.Sodium lignin sulfonate is used as dispersant, after heat-storage 14 days, indices are sufficiently stable, so scattered
Agent sodium lignin sulfonate is optimal selection.
Test four field tests preventing and treating diamondback moth
Test and tested in Zhaoqing City of Guangdong Province Gao Yao areas truck garden, diamondback moth 1-2 instar larvaes peak period.Experiment
9 processing (harm for the treatment of region diamondback moth is substantially uniform, and ecological environment is identical) are set altogether, are carried out using spray pattern, chemicals treatment
Afterwards, the method for taking random sampling (10 plants), before dispenser, 1 day after dispenser, 3 days after dispenser, after dispenser 7 days altogether investigate 4 times.
Table 6 is the investigation result of fourth chlorantraniliprole and chlorfenapyr medicament field diamondback moth
Table 7 is the result that fourth chlorantraniliprole and chlorfenapyr medicament are tested to diamondback moth field efficacy
From table 6,7 as can be seen that the preparation after fourth chlorantraniliprole and chlorfenapyr compounding is used to prevent and treat diamondback moth, its effect is bright
It is aobvious to be better than single dose.To experimental group data analysis, embodiment 10 is that fourth chlorantraniliprole and chlorfenapyr are matched as 2:When 1,1 day after medicine, 3
My god, 7 days prevention effects be all best.The fourth chlorantraniliprole and chlorfenapyr complex composition have synergistic function, and show
Go out a certain degree of resistance, can agriculturally promote the use of.
Test five field tests preventing and treating rice leaf roller
Test serious in Nanchang Rice Production base, rice leaf roller harm.Experiment sets 5 processing (treatment regions altogether
Rice leaf roller harm is substantially uniform, and ecological environment is identical), carried out using spray pattern, after chemicals treatment, take random sampling
10 plants) method, before dispenser, 1 day after dispenser, 3 days after dispenser, after dispenser 7 days altogether investigate 4 times.
Table 8 is the investigation result of fourth chlorantraniliprole and chlorfenapyr medicament field rice leaf roller
Table 9 is the result that fourth chlorantraniliprole and chlorfenapyr medicament are tested to rice leaf roller field efficacy
Shown from table 8,9 experimental datas：Fourth chlorantraniliprole and chlorfenapyr compounding proportioning are 1：When 1,1 day, 3 days, 7 days after medicine
Rice leaf roller prevention effect is prevented best.The fourth chlorantraniliprole and chlorfenapyr complex composition have synergistic function, can
Agriculturally to promote the use of.
A kind of Pesticidal combination containing fourth chlorantraniliprole and indoxacarb provided by the invention and its application, can be applicable to anti-
Harness the river the rice leaf roller of the diversified economy crop such as rice, vegetables, corn, citrus, striped rice borer, yellow rice borer, pink rice borer, bollworm, dish
Blue or green worm, diamondback moth, beet armyworm, mythimna separata etc..The compounding of fourth chlorantraniliprole and indoxacarb has relatively good prevention effect, and
The generation of the resistance of insect can effectively be delayed.Compared with unitary agent, control effect is good, lasting period length, expands desinsection,
It is obvious to compose synergistic effect.It is good to crop safety.
Embodiment described above only expresses the several embodiments of the present invention, and its description is more specific and detailed, but simultaneously
Therefore the limitation to the scope of the claims of the present invention can not be interpreted as.It should be pointed out that for one of ordinary skill in the art
For, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the guarantor of the present invention
Protect scope.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Claims (10)
- A kind of 1. Pesticidal combination containing fourth chlorantraniliprole and chlorfenapyr, it is characterised in that the composition include effectively into Divide fourth chlorantraniliprole and active ingredient chlorfenapyr；Described fourth chlorantraniliprole and the weight ratio of chlorfenapyr are 5-1：1-5.
- 2. the Pesticidal combination according to claim 1 containing fourth chlorantraniliprole and chlorfenapyr, it is characterised in that described The percentage by weight of the weight summation of fourth chlorantraniliprole and chlorfenapyr in the composition is 0.01%-50%.
- 3. the Pesticidal combination according to claim 2 containing fourth chlorantraniliprole and chlorfenapyr, it is characterised in that described The percentage by weight of the weight summation of fourth chlorantraniliprole and chlorfenapyr in the composition is 30%.
- 4. the Pesticidal combination according to claim 1 containing fourth chlorantraniliprole and chlorfenapyr, it is characterised in that described group Compound also includes auxiliary element, described auxiliary element include solvent, cosolvent, dispersant, emulsifying agent, wetting agent, disintegrant, One or more in thickener, stabilizer, defoamer, preservative, antifreeze and carrier.
- 5. the Pesticidal combination according to claim 4 containing fourth chlorantraniliprole and chlorfenapyr, it is characterised in that described Dispersant is lignosulfonates, APES or formaldehyde condensation products sodium sulphate.
- 6. the Pesticidal combination according to claim 4 containing fourth chlorantraniliprole and chlorfenapyr, it is characterised in that described Emulsifying agent is castor oil polyoxyethylene ether (EL) and/or sodium sulfate of polyethenoxy ether of fatty alcohol.
- 7. the Pesticidal combination according to claim 4 containing fourth chlorantraniliprole and chlorfenapyr, it is characterised in that described Wetting agent is neopelex.
- 8. the Pesticidal combination containing fourth chlorantraniliprole and chlorfenapyr according to claim 1-7 any one, its feature It is, the composition is applied to agricultural chemicals pharmacy.
- 9. the Pesticidal combination containing fourth chlorantraniliprole and chlorfenapyr described in claim 1-7 any one be made emulsifiable concentrate, Granule, wettable powder, water dispersible granules, microemulsion, the pesticidal preparations of suspending agent or aqueous emulsion agent.
- 10. the Pesticidal combination containing fourth chlorantraniliprole and chlorfenapyr described in claim 1-7 any one is applied to preventing and treating Rice leaf roller, striped rice borer, yellow rice borer, pink rice borer, bollworm, cabbage caterpillar, diamondback moth, beet armyworm or mythimna separata.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711210049.XA CN107743962A (en) | 2017-11-28 | 2017-11-28 | A kind of Pesticidal combination containing fourth chlorantraniliprole and chlorfenapyr and its application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711210049.XA CN107743962A (en) | 2017-11-28 | 2017-11-28 | A kind of Pesticidal combination containing fourth chlorantraniliprole and chlorfenapyr and its application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107743962A true CN107743962A (en) | 2018-03-02 |
Family
ID=61252337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711210049.XA Pending CN107743962A (en) | 2017-11-28 | 2017-11-28 | A kind of Pesticidal combination containing fourth chlorantraniliprole and chlorfenapyr and its application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107743962A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002082906A1 (en) * | 2001-04-11 | 2002-10-24 | Janssen Pharmaceutica N.V. | Pesticidal compositions comprising hydramethylnon and another insecticide |
| CN101069515A (en) * | 2007-06-27 | 2007-11-14 | 中国农业大学 | Farm chemical composition containing chlorfenapyr and phoxim |
| CN104003976A (en) * | 2014-05-07 | 2014-08-27 | 肇庆市真格生物科技有限公司 | Polysubstituted pyridyl pyrazole amide and its preparation method and use |
-
2017
- 2017-11-28 CN CN201711210049.XA patent/CN107743962A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002082906A1 (en) * | 2001-04-11 | 2002-10-24 | Janssen Pharmaceutica N.V. | Pesticidal compositions comprising hydramethylnon and another insecticide |
| CN101069515A (en) * | 2007-06-27 | 2007-11-14 | 中国农业大学 | Farm chemical composition containing chlorfenapyr and phoxim |
| CN104003976A (en) * | 2014-05-07 | 2014-08-27 | 肇庆市真格生物科技有限公司 | Polysubstituted pyridyl pyrazole amide and its preparation method and use |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101589722A (en) | A kind of insecticide composition containing chlorantraniliprole and its preparation method and application | |
| CN102362601A (en) | Insecticidal composition containing spinetoram and lythidathion | |
| CN104738066A (en) | Sterilization composition | |
| CN101861875B (en) | Synergistic pesticide compound containing mepiquat chloride and organophosphorus pesticide | |
| CN103858920A (en) | Spinetoram-containing insecticidal composition | |
| CN102440260A (en) | Insecticidal composition containing sulfoxaflor and cyhalothrin | |
| CN103478158B (en) | Insecticidal composition containing cyenopyrafen and bistrifluron | |
| CN107743962A (en) | A kind of Pesticidal combination containing fourth chlorantraniliprole and chlorfenapyr and its application | |
| CN106973937B (en) | Nematicidal composition containing cyflumetofen | |
| CN102210312A (en) | Acaricidal composition containing abamectin and fenazaquin | |
| CN104542611A (en) | Bactericidal composition containing mandipropamid | |
| CN108174853A (en) | A kind of Pesticidal combination and its preparation containing fourth chlorantraniliprole and molting hormone class | |
| CN107980789A (en) | A kind of Pesticidal combination containing fourth chlorantraniliprole and its application | |
| CN107711869A (en) | A kind of Pesticidal combination containing fourth chlorantraniliprole and indoxacarb and its application | |
| CN101708002A (en) | Synergistic pesticide composition and application thereof | |
| CN106665584B (en) | A kind of nematicidal composition containing fluopyram and furfural | |
| CN103749530B (en) | A kind of Pesticidal combination containing Avermectin | |
| CN102239858B (en) | Pesticide composition containing pyrimidifen and avermectins | |
| CN103734182B (en) | A kind of Fungicidal insecticidal composition containing mancozeb | |
| CN103704258B (en) | A kind of Fungicidal insecticidal composition containing abietic acid ketone | |
| CN108184859A (en) | One kind contains fourth chlorantraniliprole and pyrethroid Pesticidal combination and its application | |
| CN102369941B (en) | Insecticidal and acaricidal composition containing bifenazate and chlorfenapyr | |
| CN103120165A (en) | Insecticidal composition containing spinetoram and cyantraniliprole | |
| CN107333770A (en) | A kind of miticide composition containing fluorine pyrrole furanone and bromine cyanogen insect amide | |
| CN108077273A (en) | A kind of miticide composition containing second azoles mite nitrile and Amitraz |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180302 |