CN107693480B - A kind of whitening and moisturizing hand mask and preparation method thereof - Google Patents
A kind of whitening and moisturizing hand mask and preparation method thereof Download PDFInfo
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Abstract
Description
技术领域technical field
本发明涉及一种手膜,特别涉及一种嫩白滋润的手膜及其制备方法。The invention relates to a hand mask, in particular to a whitening and moisturizing hand mask and a preparation method thereof.
背景技术Background technique
随着社会的发展和科技的进步,人们承受着巨大的生活压力。因此,电脑辐射、灰尘、工作、生活压力、作息不规律、精神紧张等各种各样的因素都会成为现代人出现亚健康状态的隐患。脆弱的肌肤则更容易出现问题,特别是手部肌肤。一旦皮肤出现问题,人们就会想办法护理损伤的皮肤,尤其是女性朋友。健康的手部皮肤呈现出来的是红润细腻嫩白有光泽,而受损的肌肤看起来是暗沉粗糙的,进而会出现干燥蜕皮、缺水褶皱、毛孔粗大等问题,严重者甚至会开裂流血,并留下难以修复的疤痕。With the development of society and the advancement of science and technology, people are under enormous pressure in life. Therefore, various factors such as computer radiation, dust, work, life pressure, irregular work and rest, and mental stress will become the hidden dangers of modern people's sub-health state. Fragile skin is more prone to problems, especially on the hands. Once there is a problem with the skin, people will try to take care of the damaged skin, especially female friends. Healthy hand skin is rosy, delicate, white, and shiny, while damaged skin looks dull and rough, and then there will be problems such as dry molting, dehydration, wrinkles, enlarged pores, and even cracking and bleeding in severe cases. , and leave scars that are difficult to repair.
目前,市面上的美容护理产品虽然有很多种,但对于手部护理尚无理想产品。手是女人的第二张脸,随着年龄的增长,女性的皮肤不会再呈现十几岁时的光洁,而且也会变得十分脆弱,尤其是在冬季,手部更是由于平时工作和日常生活的原因,长时间暴露在外,更加速了手部皮肤的衰老速度。皮肤若出现以上问题中的一种或几种,带来的就不仅仅是外表上的影响,也会在潜移默化中影响我们的生活质量,给人们带来了很大的困扰。At present, although there are many kinds of beauty care products on the market, there is no ideal product for hand care. The hand is the second face of a woman. As the age increases, the skin of a woman will no longer be as smooth as she was in her teens, and it will also become very fragile, especially in winter. The reason of daily life, prolonged exposure to the outside, but also accelerated the aging speed of hand skin. If one or more of the above problems occur in the skin, it will not only affect the appearance, but also affect our quality of life subtly, causing great distress to people.
因此,发明一种无化学添加剂、纯天然植物类的手膜是很有前景的,未来也将会成为人们更好的选择。Therefore, it is very promising to invent a pure natural plant-based hand mask without chemical additives, and it will become a better choice for people in the future.
发明内容SUMMARY OF THE INVENTION
本发明的目的在于提供一种嫩白滋润的手膜,含多种天然成分提取物,加以安全无刺激性的成膜剂与增稠剂,相辅相成,有嫩白滋润等功效。The purpose of the present invention is to provide a whitening and moisturizing hand mask, which contains a variety of natural ingredient extracts, plus a safe and non-irritating film-forming agent and a thickening agent, which complement each other and have the effects of whitening and moisturizing.
本发明还提供了一种嫩白滋润的手膜的制备方法。The invention also provides a preparation method of a whitening and moisturizing hand mask.
本发明提供的一种嫩白滋润的手膜,含有以下配比的原料组分:The whitening and moisturizing hand mask provided by the invention contains the following raw material components:
所述的海带提取液是通过以下方法制备:Described kelp extract is prepared by the following method:
称取海带适量,剪碎,加水煎煮提取3次:第1次加15-18倍量水提取1-2h;第2次加12-15倍量水,提取1-1.5h;第3次加8-10倍量水,提取0.5-1.5h,每次滤过得滤液,合并滤液,滤液的体积浓缩至海带重量的3-6倍g/ml,备用。Weigh an appropriate amount of kelp, cut it into pieces, add water to decoct and extract 3 times: the first time add 15-18 times the amount of water to extract for 1-2 hours; the second time add 12-15 times the amount of water for 1-1.5 hours of extraction; the third time Add 8-10 times the amount of water, extract for 0.5-1.5h, filter each time to obtain filtrate, combine the filtrates, and concentrate the volume of the filtrate to 3-6 times g/ml of the weight of the kelp for use.
所述的白芨提取液是通过以下方法制备:The Bletilla striata extract is prepared by the following method:
称取白芨粗粉适量,用水浸泡0.25-0.75h,然后,加热煎煮提取3次:第1次加14-16倍量水,提取1-2h;第2次加12-14倍量水,提取1-1.5h;第3次加8-11倍量水,提取0.5-1.0h,每次滤过得滤液,合并滤液,滤液的体积浓缩至白芨重量的4-6倍g/ml,备用。Weigh an appropriate amount of Bletilla striata coarse powder, soak it in water for 0.25-0.75h, then heat and decoct for 3 times: add 14-16 times the amount of water for the first time, and extract for 1-2 hours; add 12-14 times the amount of water for the second time, Extract 1-1.5h; add 8-11 times of water for the third time, extract for 0.5-1.0h, filter each time to obtain filtrate, combine the filtrates, and concentrate the volume of the filtrate to 4-6 times the weight of Bletilla striata g/ml, for use .
所述的虫草花提取液是通过以下方法制备:Described cordyceps flower extract is prepared by the following method:
称取虫草花适量,用水浸泡0.2-0.7h,加热煎煮提取3次:第1次加17-20倍量水,提取1.5-2h;第2次加15-17倍量水,提取1-1.5h;第3次加13-15倍量水,提取0.5-1.0h,每次滤过得滤液,合并滤液,滤液的体积浓缩至虫草花重量的3-7倍g/ml,备用。Weigh an appropriate amount of Cordyceps flowers, soak in water for 0.2-0.7h, heat and decoct for 3 times: add 17-20 times the amount of water for the first time, extract for 1.5-2h; add 15-17 times the amount of water for the second time, extract 1- 1.5h; add 13-15 times the amount of water for the third time, extract for 0.5-1.0h, filter each time to obtain filtrate, combine the filtrates, and concentrate the volume of the filtrate to 3-7 times g/ml of the weight of Cordyceps flower, for use.
所述的薰衣草提取液是通过以下方法制备的:Described lavender extract is prepared by the following method:
称取薰衣草花适量,用75%乙醇浸泡0.5-1.0h,加热回流提取3次:第1次加17-20倍量75%乙醇,提取1-1.5h;第2次加13-16倍量75%乙醇,提取1-1.5h;第3次加8-11倍量75%乙醇,提取0.5-1.0h,每次滤过得滤液,合并滤液,将滤液的体积浓缩至薰衣草花重量的4-8倍g/ml,备用。Weigh an appropriate amount of lavender flowers, soak them in 75% ethanol for 0.5-1.0 hours, and extract under reflux for 3 times: add 17-20 times the amount of 75% ethanol for the first time, and extract for 1-1.5 hours; add 13-16 times the amount for the second time 75% ethanol, extract for 1-1.5h; add 8-11 times of 75% ethanol for the third time, extract for 0.5-1.0h, filter each time to obtain filtrate, combine the filtrates, and concentrate the volume of the filtrate to 4% of the weight of lavender flowers. -8 times g/ml, spare.
所述的草莓榨取液通过以下方法制备:Described strawberry squeezed liquid is prepared by the following method:
称取草莓适量,加入10-18倍蒸馏水,榨汁,过滤,离心,取上清液备用;Weigh an appropriate amount of strawberries, add 10-18 times distilled water, squeeze the juice, filter, centrifuge, and take the supernatant for later use;
所述的樱桃榨取液通过以下方法制备:Described cherry squeezed liquid is prepared by the following method:
称取去籽樱桃适量,加入8-16倍蒸馏水,榨汁,过滤,离心,取上清液备用;Weigh an appropriate amount of seeded cherries, add 8-16 times distilled water, squeeze the juice, filter, centrifuge, and take the supernatant for use;
所述的杨梅榨取液通过以下方法制备:Described bayberry extract is prepared by the following method:
称取杨梅适量,加入10-15倍蒸馏水,榨汁,过滤,离心,取上清液备用。Weigh an appropriate amount of bayberry, add 10-15 times distilled water, squeeze the juice, filter, centrifuge, and take the supernatant for later use.
所述香精选自青瓜香精、水蜜桃香精、牛奶香精、玫瑰香精、桂花香精、茉莉香精或柠檬香精中的一种或多种。The fragrance is selected from one or more of cucumber essence, peach essence, milk essence, rose essence, sweet-scented osmanthus essence, jasmine essence or lemon essence.
本发明提供的一种嫩白滋润手膜的制备方法包括以下步骤:The preparation method of a kind of whitening and moisturizing hand mask provided by the present invention comprises the following steps:
a)称取羧甲基纤维素钠0.05-0.10g,加入到15-25ml蒸馏水中,40-50℃水浴加热,边加热边搅拌,静置让其充分溶胀、溶解,形成羧甲基纤维素钠凝胶液,待用;a) Weigh 0.05-0.10 g of sodium carboxymethyl cellulose, add it to 15-25 ml of distilled water, heat in a water bath at 40-50 ° C, stir while heating, let it stand still to fully swell and dissolve, and form carboxymethyl cellulose Sodium gel solution, ready for use;
b)称取海藻酸钠0.02-0.09g,加入到10-20ml蒸馏水中,60-80℃水浴加热,边加热边搅拌,静置让其充分溶胀、溶解,形成均匀的海藻酸钠凝胶液,待用;b) Weigh 0.02-0.09g of sodium alginate, add it to 10-20ml of distilled water, heat in a water bath at 60-80°C, stir while heating, let it stand still to fully swell and dissolve, and form a uniform sodium alginate gel ,stand-by;
c)称取羟丙基甲基纤维素0.03-0.12g,加入到20-30ml蒸馏水中,静置让其充分溶胀、溶解,形成羟丙基甲基纤维素凝胶液,待用;c) Weigh 0.03-0.12 g of hydroxypropyl methylcellulose, add it to 20-30 ml of distilled water, let it stand still to fully swell and dissolve, and form a hydroxypropyl methylcellulose gel solution, which is ready for use;
d)称取甲基纤维素0.03-0.11g,加入到15-25ml蒸馏水中,静置让其充分溶胀、溶解,形成甲基纤维素凝胶液,待用;d) Weigh 0.03-0.11 g of methyl cellulose, add it to 15-25 ml of distilled water, let it stand still to fully swell and dissolve, and form a methyl cellulose gel solution for use;
e)称取聚乙烯醇0.35-0.55g,加入到25-35ml蒸馏水中,90-100℃水浴加热,边加热边搅拌,静置让其充分溶胀、溶解,形成聚乙烯醇凝胶液,待用;e) Weigh 0.35-0.55g of polyvinyl alcohol, add it to 25-35ml of distilled water, heat it in a water bath at 90-100°C, stir while heating, let it stand still to fully swell and dissolve, and form a polyvinyl alcohol gel solution. use;
f)将步骤a)、步骤b)、步骤c)、步骤d)和步骤e)制备的凝胶液混合搅拌,形成均匀的凝胶基质,待用;f) mixing and stirring the gel liquid prepared in step a), step b), step c), step d) and step e) to form a uniform gel matrix, ready for use;
g)分别量取海带提取液0.3-1.5ml、白芨提取液0.2-1.0ml、虫草花提取液0.6-1.8ml、薰衣草提取液0.2-1.2ml、草莓榨取液0.5-1.8ml、樱桃榨取液0.5-1.8ml、杨梅榨取液0.6-2.0ml混合,搅拌均匀,形成溶液1,待用;g) Measure 0.3-1.5ml of kelp extract, 0.2-1.0ml of Bletilla striata extract, 0.6-1.8ml of Cordyceps flower extract, 0.2-1.2ml of lavender extract, 0.5-1.8ml of strawberry extract, 0.5ml of cherry extract -1.8ml, mixed with 0.6-2.0ml of bayberry extract, stir evenly to form solution 1, ready for use;
h)称取烟酰胺0.2-1.3g,加入到4-9ml蒸馏水中,静置让其充分溶解,形成烟酰胺溶液,待用;h) Weigh 0.2-1.3 g of nicotinamide, add it to 4-9 ml of distilled water, let it be fully dissolved by standing to form a nicotinamide solution, and stand by;
i)称取海藻糖0.5-2.0g,加入8-15ml的蒸馏水,静置让其充分溶解,形成海藻糖溶液,待用;i) Weigh 0.5-2.0 g of trehalose, add 8-15 ml of distilled water, and let it be fully dissolved by standing to form a trehalose solution for use;
j)称取尼泊金乙酯0.15-0.3g,溶于75%乙醇1-3ml中,形成防腐剂溶液,待用;j) Weigh 0.15-0.3 g of ethyl paraben and dissolve it in 1-3 ml of 75% ethanol to form a preservative solution, ready for use;
k)称取奶粉0.4-1.6g,加蒸馏水5-10ml,搅拌溶解,形成牛奶溶液,待用;k) Weigh 0.4-1.6g of milk powder, add 5-10ml of distilled water, stir to dissolve, form a milk solution, and stand by;
l)将烟酰胺溶液、海藻糖溶液与牛奶溶液混合搅拌均匀,形成溶液2,待用;1) nicotinamide solution, trehalose solution and milk solution are mixed and stirred to form solution 2, for use;
m)分别向步骤f)制备的凝胶基质中加入溶液1、溶液2、防腐剂溶液、甘油1.0-3.0g、蜂蜜0.2-1.1g和香精0.05-0.3ml,搅拌均匀,即得细腻均匀嫩白滋润手膜。m) Add solution 1, solution 2, preservative solution, glycerin 1.0-3.0g, honey 0.2-1.1g and essence 0.05-0.3ml to the gel matrix prepared in step f) respectively, and stir evenly to obtain fine, uniform and tender White moisturizing hand mask.
本发明中的各种成分如下:Various components in the present invention are as follows:
海带中富含钙等多种元素,不仅能美容,还有延缓衰老的作用。本发明提取的海带提取液,可以美容养颜,润泽肌肤,使皮肤清爽细滑、光洁美丽。海带富含硒,能有效清除自由基,而自由基正是人体衰老的罪魁祸首,本发明中海带提取液可以起到护肤、延缓衰老的作用。Kelp is rich in calcium and other elements, which can not only beautify, but also delay aging. The kelp extract extracted by the present invention can beautify the skin, moisturize the skin, and make the skin refreshing, smooth, smooth and beautiful. Kelp is rich in selenium, which can effectively remove free radicals, and free radicals are the main culprit of human aging.
白芨是一味古老的收敛止血、美容养颜的中药,被誉为“美白仙子”。白芨富含的白芨胶更是可以直接参与受损组织或细胞的修复和代谢过程,能显著促进角质细胞的形成。外用涂擦,可以美容消斑,让肌肤光滑无痕。将白芨胶加入抗衰老、营养肌肤的化妆品中,可补充肌肤营养、消除体内过量的自由基、延缓肌肤衰老。《药性论》云其“治面上疮,令人肌滑”。《本草纲目》云其“洗面黑,祛斑”。白芨还具有润肤抗皱,改善皮肤营养状况,治疗手足皲裂以及延缓肌肤衰老等功效。因此,白芨是一种理想的化妆品天然植物添加物,它能滋润皮肤,令肌肤光滑如玉。Bletilla striata is an ancient traditional Chinese medicine for astringent hemostasis, beauty and beauty, known as "whitening fairy". Bletilla striata, which is rich in Bletilla striata gum, can directly participate in the repair and metabolism of damaged tissues or cells, and can significantly promote the formation of keratinocytes. Rubbed externally, it can beautify the spots and make the skin smooth and without traces. Adding Bletilla striata gum to anti-aging and nourishing skin cosmetics can supplement skin nutrition, eliminate excess free radicals in the body, and delay skin aging. "Medicinal Properties" says that it "treats sores on the face and makes the muscles slippery". "Compendium of Materia Medica" Yunqi "wash the face black, remove freckles". Bletilla striata also has the functions of moisturizing and anti-wrinkling, improving skin nutrition, treating chapped hands and feet, and delaying skin aging. Therefore, Bletilla striata is an ideal natural botanical additive for cosmetics, which can moisturize the skin and make it smooth as jade.
虫草花含有多种丰富的营养物质,可以补血养颜、润肌护肤,有良好的美容作用。虫草花中的多糖能消除自由基、提高抗氧化酶活性和抑制脂质过氧化活性的能力,起到保护生物膜和延缓衰老的作用;其所含的蛋白质、氨基酸能促进细胞的代谢,有利于细胞的再生。虫草花还能提高人体机体耐寒能力,减轻疲劳,延缓皮肤衰老。Cordyceps flower contains a variety of rich nutrients, which can nourish blood, nourish skin, moisturize skin and skin care, and have a good cosmetic effect. The polysaccharides in Cordyceps flowers can eliminate free radicals, improve the activity of antioxidant enzymes and inhibit the activity of lipid peroxidation, and play a role in protecting biofilms and delaying aging; the proteins and amino acids contained in them can promote cell metabolism and have Conducive to cell regeneration. Cordyceps can also improve the cold tolerance of the human body, reduce fatigue, and delay skin aging.
薰衣草被称为“百草之王”,有利于伤口的愈合,具有祛疤痕,控油,再生,消炎,修复受损肌肤等功效。薰衣草适合任何皮肤,能促进细胞再生,让肌肤保持弹性,延缓肌肤衰老。薰衣草提取物还有有清洁皮肤的功效,可以抑制皮肤表面细菌的生长,避免引发皮肤感染;安抚皮肤,平衡皮肤油脂分泌过多。Lavender is known as the "King of Herbs", which is beneficial to wound healing, and has the functions of removing scars, controlling oil, regenerating, anti-inflammatory, and repairing damaged skin. Lavender is suitable for any skin, can promote cell regeneration, keep skin elastic and delay skin aging. Lavender extract also has the effect of cleansing the skin, which can inhibit the growth of bacteria on the skin surface and avoid causing skin infections; soothe the skin and balance excessive skin oil secretion.
蜂蜜味甘、性平,含有人体所需的多种有益人体健康的微量元素,能够促进血液循环、加速肌肤新生,长期使用蜂蜜具有润肤美白、祛斑除皱、延缓衰老的功效。蜂蜜还具有保湿和滋养的作用,冬季皮肤干燥开裂,用蜂蜜涂抹,促进皮肤细胞的新陈代谢,改善皮肤的营养状况,能使皮肤红润细腻、光洁嫩白、富有弹性。蜂蜜还可以抑制表层皮肤细菌的生长,起到保护皮肤、清洁皮肤的作用。Honey is sweet in taste and flat in nature. It contains a variety of trace elements needed by the human body that are beneficial to human health. It can promote blood circulation and accelerate skin regeneration. Long-term use of honey has the effects of moisturizing and whitening, freckle and wrinkle removal, and anti-aging. Honey also has moisturizing and nourishing functions. In winter, when the skin is dry and cracked, applying honey can promote the metabolism of skin cells, improve the nutritional status of the skin, and make the skin rosy, delicate, bright, white and elastic. Honey can also inhibit the growth of bacteria on the surface of the skin, protect the skin and clean the skin.
牛奶含有丰富的蛋白质、乳脂肪、维他命、矿物质等对人体健康有益的成分。牛奶中含有丰富的锌元素,有助于伤口快速愈合;丰富的乳脂能有效改变皮肤干燥的现象,极大改善肤质;酵素成分能达到消炎、消肿、止痛与舒缓皮肤的功效;乳清对面部皱纹有消除作用,可使皮肤保持光滑滋润。牛奶还具有天然的保湿效果,也很容易被皮肤吸收,能起到滋养肌肤、收敛毛孔、去除暗沉、美白润肤的作用。牛奶还能有效地防止皱纹滋生,让肌肤非常的柔软细滑。Milk is rich in protein, milk fat, vitamins, minerals and other ingredients that are beneficial to human health. Milk is rich in zinc, which helps wounds heal quickly; rich milk fat can effectively change the phenomenon of dry skin and greatly improve skin quality; enzymes can achieve anti-inflammatory, swelling, pain relief and skin soothing effects; whey It has the effect of eliminating wrinkles on the face and keeping the skin smooth and moisturised. Milk also has a natural moisturizing effect and is easily absorbed by the skin, which can nourish the skin, shrink pores, remove dullness, and whiten and moisturize the skin. Milk can also effectively prevent wrinkles and make the skin very soft and smooth.
烟酰胺也称维生素B3,具有良好的水溶性,可迅速透过皮肤角质层,抑制黑色素输送途径,具有多重美白、抗皱、抗衰老的效果。烟酰胺还可以改善皮肤的屏障作用,有深层锁水功效,降低表皮失水率,对皮肤有极强的保湿功效。通过减少皮肤油脂的分泌,缩小毛孔,使皮肤纹理细腻光滑,促进表皮层蛋白质的合成,改善肌肤质地,减少皱纹。Niacinamide, also known as vitamin B 3 , has good water solubility, can quickly penetrate the stratum corneum of the skin, inhibit the melanin transport pathway, and has multiple whitening, anti-wrinkle, and anti-aging effects. Niacinamide can also improve the skin's barrier function, has a deep water-locking effect, reduces the rate of epidermal water loss, and has a strong moisturizing effect on the skin. By reducing the secretion of skin oil, reducing pores, making the skin texture delicate and smooth, promoting the synthesis of epidermal protein, improving skin texture and reducing wrinkles.
海藻糖对细胞膜、蛋白结构都有一定的保护作用,有利于细胞的代谢。海藻糖具有补水、抗衰和修复愈合受损肌肤等多重功效,能在细胞表层形成一层保护膜,保持皮肤营养和水分,延缓皮肤衰老,具有一定的护肤作用。海藻糖还具有极强的保湿作用和多方面的生理功效性,易于被皮肤吸收,是一种多功能的化妆品生物活性添加剂,在皮肤的抗衰老、抗疲劳、抗损伤、补充能量、伤口修复、防晒、晒后修复中都有应用。Trehalose has a certain protective effect on cell membrane and protein structure, which is beneficial to cell metabolism. Trehalose has multiple functions such as moisturizing, anti-aging and repairing and healing damaged skin. It can form a protective film on the surface of cells to maintain skin nutrition and moisture, delay skin aging, and has a certain skin care effect. Trehalose also has a strong moisturizing effect and various physiological functions, and is easily absorbed by the skin. It is a multi-functional cosmetic bioactive additive. , sunscreen, after-sun repair have applications.
海藻酸钠是常用的增稠剂与稳定剂,具有抗静电及稳泡等作用。能够使产品具有良好的稳定性、均一性,减少液体的渗出。因其能改善皮肤的保湿性,使皮肤水嫩,所以常用作化妆品的增稠剂与稳定剂。Sodium alginate is a commonly used thickener and stabilizer, which has the functions of antistatic and foam stabilization. It can make the product have good stability and uniformity, and reduce the exudation of liquid. Because it can improve the moisturizing property of the skin and make the skin supple, it is often used as a thickener and stabilizer for cosmetics.
羧甲基纤维素钠有良好的增稠性与稳定性,无毒、无刺激性。将它应用在本处方中能增加成品的稳定性。此外,羧甲基纤维素钠的分散性良好,有利于形成稳定的体系。Sodium carboxymethyl cellulose has good thickening and stability, non-toxic and non-irritating. Its use in this formulation increases the stability of the finished product. In addition, the dispersibility of sodium carboxymethyl cellulose is good, which is conducive to the formation of a stable system.
甲基纤维素具有优良的润湿性、分散性、增稠性、保水性和成膜性等,所成膜具有优良的韧性、柔曲性和透明度,可以增加化妆品的粘稠度与稳定性。Methyl cellulose has excellent wettability, dispersibility, thickening, water retention and film-forming properties, etc. The formed film has excellent toughness, flexibility and transparency, which can increase the viscosity and stability of cosmetics. .
聚乙烯醇具有良好的成膜性能。聚乙烯醇在用于经皮给药时,有利于药物释放并与皮肤或病灶相接触;可增加凝胶基质与皮肤角质层的水合程度,促进药物的渗透,提高疗效。此外,它还具有辅助增溶、乳化及稳定的作用,在成膜的同时还能增加药物的溶解性、体系的稳定性。Polyvinyl alcohol has good film-forming properties. When used for percutaneous administration, polyvinyl alcohol is conducive to drug release and contact with skin or lesions; it can increase the hydration degree of gel matrix and skin stratum corneum, promote drug penetration, and improve curative effect. In addition, it also has the functions of auxiliary solubilization, emulsification and stabilization, and can also increase the solubility of the drug and the stability of the system while forming a film.
羟丙基甲基纤维素具有一定的成膜性、稳定性、增稠性等。作为添加剂使用时,可有效改善体系的流动性,增强附着力以及粘结强度提高其它材料的成膜效果,改善肤感。此外还可以作为分散剂,提高药物的分散性,有利于药效的发挥且对皮肤、黏膜接触无刺激。Hydroxypropyl methylcellulose has certain film-forming properties, stability and thickening properties. When used as an additive, it can effectively improve the fluidity of the system, enhance adhesion and bond strength, improve the film-forming effect of other materials, and improve skin feel. In addition, it can also be used as a dispersant to improve the dispersibility of the drug, which is beneficial to the exertion of the drug effect and has no irritation to the skin and mucous membranes.
甘油吸收快,对换季脱皮的肌肤、痘痘留疤的肌肤、敏感性肌肤等都是补水佳品。纯度较高的甘油兑水后使用,保湿滋润效果非常好,用后的皮肤水润、柔软,摸起来很舒服。甘油是一种动态的保湿剂,搽在皮肤上能形成一层薄膜,有隔绝空气和防止水分蒸发的作用,还能吸收空气中的水分。甘油性质温和能够带来柔和的补水效果,让肌肤柔软、有弹性。对皮肤安全性佳,不易引起过敏。Glycerin absorbs quickly, and is a good hydrating product for peeling skin in seasons, skin with acne scars, and sensitive skin. The high-purity glycerin is mixed with water and used, and the moisturizing effect is very good. After use, the skin is moist, soft and comfortable to touch. Glycerin is a dynamic moisturizing agent that forms a thin film on the skin, which can isolate the air and prevent the evaporation of water, and can also absorb the moisture in the air. The mild nature of glycerin provides gentle hydration, leaving skin soft and supple. Good safety to the skin, not easy to cause allergies.
本发明的聚乙烯醇、甲基纤维素具有良好的成膜性;海藻酸钠、羧甲基纤维素钠能增加体系的稳定性;烟酰胺、牛奶与甘油共奏保湿功效;海带、白芨、海藻糖、蜂蜜与虫草花相辅相成,能延缓肌肤的衰老;虫草花、薰衣草、牛奶具有抗氧化、消炎的功效;蜂蜜、牛奶、烟酰胺相互辅佐,使肌肤嫩白细腻。The polyvinyl alcohol and methyl cellulose of the present invention have good film-forming properties; sodium alginate and sodium carboxymethyl cellulose can increase the stability of the system; niacinamide, milk and glycerin play a moisturizing effect together; Trehalose, honey and Cordyceps flower complement each other to delay skin aging; Cordyceps flower, Lavender, and milk have antioxidant and anti-inflammatory effects; Honey, milk, and niacinamide complement each other to make skin white and delicate.
本发明采用天然药物提取物为原料,加以安全无刺激性的成膜剂与增稠剂,相辅相成,有延缓衰老、抗氧化、修复受损细胞等功效。制备的手膜不仅可以嫩白滋润,而且,可以去角质淡化细纹,抗氧化、消炎、抗衰老。本发明与现有技术相比具有起效快,副作用小等特点,产品均匀细腻,气味芳香,有效成分可以深层渗入手部皮肤,达到滋养、美白、修复的效果,使手部肌肤嫩白、红润、有光泽。The present invention adopts natural medicine extract as raw material, adds safe and non-irritating film-forming agent and thickening agent to complement each other, and has the functions of delaying aging, anti-oxidation, repairing damaged cells and the like. The prepared hand mask can not only whiten and moisturise, but also can exfoliate and lighten fine lines, anti-oxidation, anti-inflammatory and anti-aging. Compared with the prior art, the present invention has the characteristics of quick onset, less side effects, uniform and delicate products, fragrant smell, and effective ingredients can penetrate deeply into the skin of the hands, so as to achieve the effects of nourishing, whitening and repairing, so that the skin of the hands is tender and white. Ruddy and shiny.
具体实施方式Detailed ways
下面结合实施例对本发明做进一步的描述,本发明中乙醇浓度均为体积浓度。The present invention will be further described below in conjunction with the examples, and the ethanol concentration in the present invention is the volume concentration.
实施例1Example 1
一种嫩白滋润的手膜,含有以下配比的原料组分:A whitening and moisturizing hand mask, which contains the following raw material components:
1.1海带提取液的制备1.1 Preparation of kelp extract
称取海带50g,剪碎,加水煎煮提取3次:第1次加15倍量水提取1h;第2次加12倍量水,提取1h;第3次加8倍量水,提取0.5h,每次滤过得滤液,合并滤液,滤液的体积浓缩至海带重量的3倍g/ml,备用。Weigh 50g of kelp, cut into pieces, add water to decoct and extract 3 times: the first time, add 15 times the amount of water for 1 hour; the second time, add 12 times the amount of water, and extract for 1 hour; the third time, add 8 times the amount of water, and extract for 0.5h , the filtrate is obtained by filtration each time, the filtrate is combined, and the volume of the filtrate is concentrated to 3 times g/ml of the weight of the kelp, for use.
1.2白芨提取液的制备1.2 Preparation of Bletilla striata extract
称取白芨粗粉80g,用水浸泡0.25h,加热煎煮提取3次:第1次加14倍量水,提取1h;第2次加12倍量水,提取1h;第3次加8倍量水,提取1.0h,每次滤过得滤液,合并滤液,滤液的体积浓缩至白芨重量的4倍g/ml,备用。Weigh 80g of Bletilla striata coarse powder, soak it in water for 0.25h, heat and decoct for 3 times: add 14 times the amount of water for the first time, and extract for 1 hour; add 12 times the amount of water for the second time, and extract for 1 hour; add 8 times the amount of water for the third time. Water, extract for 1.0h, filter each time to obtain filtrate, combine the filtrates, and concentrate the volume of the filtrate to 4 times the weight of Bletilla striata g/ml, for use.
1.3虫草花提取液的制备1.3 Preparation of Cordyceps Flower Extract
称取虫草花30g,用水浸泡0.3h,加热煎煮提取3次:第1次加17倍量水,提取1.5h;第2次加15倍量水,提取1h;第3次加13-15倍量水,提取0.5h,每次滤过得滤液,合并滤液,滤液的体积浓缩至虫草花重量的3倍g/ml,备用。Weigh 30g of Cordyceps flowers, soak in water for 0.3h, heat and decoct for 3 times: add 17 times the amount of water for the first time and extract for 1.5h; add 15 times the amount of water for the second time, extract for 1h; add 13-15 times the amount of water for the third time Double the amount of water, extract for 0.5h, filter each time to obtain filtrate, combine the filtrate, and concentrate the volume of the filtrate to 3 times g/ml of the weight of the Cordyceps flower, for later use.
1.4薰衣草提取液的制备1.4 Preparation of Lavender Extract
称取薰衣草花35g,用75%乙醇浸泡0.5h,加热回流提取3次:第1次加20倍量75%乙醇,提取1h;第2次加13倍量75%乙醇,提取1h;第3次加8倍量75%乙醇,提取0.5h,每次滤过得滤液,合并滤液,将滤液的体积浓缩至薰衣草花重量的4倍g/ml,备用。Weigh 35 g of lavender flowers, soak them in 75% ethanol for 0.5 h, and extract by heating and refluxing for 3 times: for the first time, add 20 times the amount of 75% ethanol for 1 h; for the second time, add 13 times the amount of 75% ethanol for 1 h; Add 8 times the amount of 75% ethanol, extract for 0.5h, filter each time to obtain filtrate, combine the filtrates, and concentrate the volume of the filtrate to 4 times g/ml of the weight of the lavender flower, for later use.
1.5草莓榨取液的制备1.5 Preparation of strawberry extract
称取草莓40g,加入10倍蒸馏水,置于榨汁机内榨汁,四层纱布过滤,置于离心机内2500rpm,离心10min,取上清液备用;Weigh 40 g of strawberries, add 10 times distilled water, place in a juicer to squeeze the juice, filter with four layers of gauze, place in a centrifuge at 2500 rpm, centrifuge for 10 min, and take the supernatant for later use;
1.6樱桃榨取液的制备1.6 Preparation of cherry extract
称取去籽樱桃30g,加入8倍蒸馏水,置于榨汁机内榨汁,四层纱布过滤,置于离心机内2500rpm,离心10min,取上清液备用;Weigh 30 g of deseeded cherries, add 8 times distilled water, place in a juicer to extract juice, filter with four layers of gauze, place in a centrifuge at 2500 rpm, centrifuge for 10 min, and take the supernatant for later use;
1.7杨梅榨取液的制备1.7 Preparation of bayberry extract
称取杨梅40g,加入10倍蒸馏水,置于榨汁机内榨汁,四层纱布过滤,置于离心机内2500rpm,离心15min,取上清液备用。Weigh 40 g of bayberry, add 10 times of distilled water, put it in a juicer to squeeze the juice, filter with four layers of gauze, put it in a centrifuge at 2500 rpm, centrifuge for 15 min, and take the supernatant for later use.
1.8嫩白滋润去角质淡化细纹手膜的制备1.8 Preparation of whitening, moisturizing, exfoliating and fine-wrinkle hand mask
a)称取羧甲基纤维素钠0.05g,加入到装有15ml蒸馏水的烧杯中,40℃水浴加热,边加热边搅拌,静置让其充分溶胀、溶解,形成羧甲基纤维素钠凝胶液,待用;a) Weigh 0.05 g of sodium carboxymethyl cellulose, add it to a beaker containing 15 ml of distilled water, heat in a water bath at 40°C, stir while heating, and let it stand to fully swell and dissolve to form sodium carboxymethyl cellulose coagulation. glue, ready to use;
b)称取海藻酸钠0.02g,加入到装有10ml蒸馏水的烧杯中,60℃水浴加热,边加热边搅拌,静置让其充分溶胀、溶解,形成均匀的海藻酸钠凝胶液,待用;b) Weigh 0.02 g of sodium alginate, add it to a beaker containing 10 ml of distilled water, heat in a water bath at 60°C, stir while heating, let it stand still to fully swell and dissolve, and form a uniform sodium alginate gel solution. use;
c)称取羟丙基甲基纤维素0.03g,加入到盛有20ml蒸馏水的烧杯中,静置让其充分溶胀、溶解,形成羟丙基甲基纤维素凝胶液,待用;c) Weigh 0.03 g of hydroxypropyl methylcellulose, add it to a beaker containing 20ml of distilled water, let it stand still to fully swell and dissolve, and form a hydroxypropyl methylcellulose gel solution, which is ready for use;
d)称取甲基纤维素0.03g,加入到装有15ml蒸馏水的烧杯中,静置让其充分溶胀、溶解,形成甲基纤维素凝胶液,待用;d) Weigh 0.03 g of methylcellulose, add it to a beaker containing 15ml of distilled water, let it stand still to fully swell and dissolve, and form a methylcellulose gel solution for use;
e)称取聚乙烯醇0.35g,加入到装有25ml蒸馏水的烧杯中,90℃水浴加热,边加热边搅拌,静置让其充分溶胀、溶解,形成聚乙烯醇凝胶液,待用;e) weigh 0.35g of polyvinyl alcohol, add it to a beaker containing 25ml of distilled water, heat in a 90°C water bath, stir while heating, let it stand still to fully swell and dissolve, and form a polyvinyl alcohol gel solution, ready for use;
f)五种凝胶液混合搅拌,形成均匀的凝胶基质,待用;f) five kinds of gel liquids are mixed and stirred to form a uniform gel matrix, which is ready for use;
g)分别量取海带提取液0.3ml、白芨提取液0.2ml、虫草花提取液0.6ml、薰衣草提取液0.2ml、草莓榨取液0.5ml、樱桃榨取液0.5ml、杨梅榨取液0.6ml置于烧杯中,搅拌均匀,形成溶液1,待用;g) Measure 0.3ml of kelp extract, 0.2ml of Bletilla striata extract, 0.6ml of cordyceps flower extract, 0.2ml of lavender extract, 0.5ml of strawberry extract, 0.5ml of cherry extract, and 0.6ml of bayberry extract, respectively, and place them in a beaker , stir evenly to form solution 1, ready to use;
h)称取烟酰胺0.2g,加入到装有4ml蒸馏水的烧杯中,静置让其充分溶解,形成烟酰胺溶液,待用;h) Weigh 0.2 g of nicotinamide, add it to a beaker containing 4 ml of distilled water, and let it be fully dissolved by standing to form a nicotinamide solution for use;
i)称取海藻糖0.5g,装入烧杯中,加入8ml的蒸馏水,静置让其充分溶解,形成海藻糖溶液,待用;i) Weigh 0.5g of trehalose, put it into a beaker, add 8ml of distilled water, let it stand still to be fully dissolved, and form a trehalose solution for use;
j)称取尼泊金乙酯0.15g,溶于75%乙醇1ml中,形成防腐剂溶液,待用;j) Weigh 0.15 g of ethyl paraben, dissolve it in 1 ml of 75% ethanol to form a preservative solution, and stand by;
k)称取奶粉0.4g,加蒸馏水5ml,搅拌溶解,形成牛奶溶液,待用;k) Weigh 0.4g of milk powder, add 5ml of distilled water, stir to dissolve, form a milk solution, and stand by;
l)将烟酰胺溶液、海藻糖溶液与牛奶溶液混合搅拌均匀,形成溶液2,待用;1) nicotinamide solution, trehalose solution and milk solution are mixed and stirred to form solution 2, for use;
m)分别向凝胶基质中加入溶液1、溶液2、防腐剂溶液、甘油1.0g、蜂蜜0.2g和水蜜桃香精0.05ml,搅拌均匀,即得细腻均匀嫩白滋润去角质淡化细纹手膜。m) Add solution 1, solution 2, preservative solution, glycerin 1.0g, honey 0.2g and peach essence 0.05ml to the gel matrix respectively, stir evenly, that is, a delicate and even whitening, moisturizing, exfoliating and fine-wrinkle hand mask is obtained. .
实施例2Example 2
一种嫩白滋润的手膜,含有以下配比的原料组分:A whitening and moisturizing hand mask, which contains the following raw material components:
2.1海带提取液的制备2.1 Preparation of kelp extract
称取海带60g,剪碎,加水煎煮提取3次:第1次加16倍量水提取1.5h;第2次加14倍量水,提取1h;第3次加9倍量水,提取1h,每次滤过得滤液,合并滤液,滤液的体积浓缩至海带重量的4倍g/ml,备用。Weigh 60g of kelp, cut it into pieces, add water to decoct and extract for 3 times: the first time, add 16 times the amount of water to extract for 1.5 hours; the second time, add 14 times the amount of water, and extract for 1 hour; the third time, add 9 times the amount of water, and extract for 1 hour. , the filtrate was obtained by filtration each time, the filtrate was combined, and the volume of the filtrate was concentrated to 4 times the g/ml of the kelp weight, and was used for later use.
2.2白芨提取液的制备2.2 Preparation of Bletilla striata extract
称取白芨粗粉45g,用水浸泡0.5h,加热煎煮提取3次:第1次加15倍量水,提取1.5h;第2次加13倍量水,提取1h;第3次加10倍量水,提取0.5h,每次滤过得滤液,合并滤液,滤液的体积浓缩至白芨重量的5倍g/ml,备用。Weigh 45g of Bletilla striata coarse powder, soak it in water for 0.5h, heat and decoct for 3 times: add 15 times the amount of water for the first time, extract for 1.5h; add 13 times the amount of water for the second time, extract for 1h; add 10 times the amount of water for the third time amount of water, extract for 0.5h, filter each time to obtain filtrate, combine the filtrates, and concentrate the volume of the filtrate to 5 times the weight of Bletilla striata g/ml, for later use.
2.3虫草花提取液的制备2.3 Preparation of Cordyceps Flower Extract
称取虫草花30g,用水浸泡0.5h,加热煎煮提取3次:第1次加18倍量水,提取1.5h;第2次加16倍量水,提取1h;第3次加14倍量水,提取0.5h,每次滤过得滤液,合并滤液,滤液的体积浓缩至虫草花重量的6倍g/ml,备用。Weigh 30g of Cordyceps flowers, soak in water for 0.5h, heat and decoct for 3 times: add 18 times the amount of water for 1.5h for the first time; add 16 times the amount of water for 1 hour for the second time; add 14 times the amount for the third time Water, extract for 0.5h, filter each time to obtain filtrate, combine the filtrates, and concentrate the volume of the filtrate to 6 times g/ml of the weight of the Cordyceps flower, for later use.
2.4薰衣草提取液的制备2.4 Preparation of lavender extract
称取薰衣草花25g,用75%乙醇浸泡0.8h,加热回流提取3次:第1次加18倍量75%乙醇,提取1h;第2次加15倍量75%乙醇,提取1h;第3次加10倍量75%乙醇,提取0.5h,每次滤过得滤液,合并滤液,将滤液的体积浓缩至薰衣草花重量的7倍g/ml,备用。Weigh 25 g of lavender flowers, soak them in 75% ethanol for 0.8 h, and extract by heating and refluxing for 3 times: for the first time, add 18 times the amount of 75% ethanol, and extract for 1 h; for the second time, add 15 times the amount of 75% ethanol, and extract for 1 h; Add 10 times the amount of 75% ethanol each time, extract for 0.5h, filter each time to obtain a filtrate, combine the filtrates, and concentrate the volume of the filtrate to 7 times the weight of the lavender flower g/ml for use.
2.5草莓榨取液的制备2.5 Preparation of strawberry extract
称取草莓40g,加入15倍蒸馏水,置于榨汁机内榨汁,四层纱布过滤,置于离心机内2800rpm,离心12min,取上清液备用;Weigh 40 g of strawberries, add 15 times distilled water, place in a juicer to squeeze the juice, filter with four layers of gauze, place in a centrifuge at 2800 rpm, centrifuge for 12 min, and take the supernatant for later use;
2.6樱桃榨取液的制备2.6 Preparation of cherry extract
称取去籽樱桃30g,加入12倍蒸馏水,置于榨汁机内榨汁,四层纱布过滤,置于离心机内2800rpm,离心15min,取上清液备用;Weigh 30 g of deseeded cherries, add 12 times distilled water, place in a juicer to extract juice, filter with four layers of gauze, place in a centrifuge at 2800 rpm, centrifuge for 15 min, and take the supernatant for use;
2.7杨梅榨取液的制备2.7 Preparation of bayberry extract
称取杨梅30g,加入14倍蒸馏水,置于榨汁机内榨汁,四层纱布过滤,置于离心机内2800rpm,离心12min,取上清液备用。Weigh 30 g of bayberry, add 14 times of distilled water, put it in a juicer to squeeze the juice, filter with four layers of gauze, put it in a centrifuge at 2800 rpm, centrifuge for 12 min, and take the supernatant for later use.
2.8嫩白滋润去角质淡化细纹手膜的制备2.8 Preparation of whitening, moisturizing, exfoliating and fine-wrinkle hand mask
a)称取羧甲基纤维素钠0.08g,加入到装有20ml蒸馏水的烧杯中,45℃水浴加热,边加热边搅拌,静置让其充分溶胀、溶解,形成羧甲基纤维素钠凝胶液,待用;a) Weigh 0.08 g of sodium carboxymethyl cellulose, add it to a beaker containing 20 ml of distilled water, heat in a water bath at 45°C, stir while heating, let it stand still to fully swell and dissolve, and form sodium carboxymethyl cellulose coagulation glue, ready to use;
b)称取海藻酸钠0.05g,加入到装有15ml蒸馏水的烧杯中,70℃水浴加热,边加热边搅拌,静置让其充分溶胀、溶解,形成均匀的海藻酸钠凝胶液,待用;b) Weigh 0.05 g of sodium alginate, add it to a beaker containing 15 ml of distilled water, heat in a water bath at 70°C, stir while heating, let it stand still to fully swell and dissolve, and form a uniform sodium alginate gel solution. use;
c)称取羟丙基甲基纤维素0.09g,加入到盛有26ml蒸馏水的烧杯中,静置让其充分溶胀、溶解,形成羟丙基甲基纤维素凝胶液,待用;c) Weigh 0.09g of hydroxypropyl methylcellulose, add it to a beaker containing 26ml of distilled water, let it stand still to fully swell and dissolve, and form a hydroxypropyl methylcellulose gel solution, which is ready for use;
d)称取甲基纤维素0.07g,加入到装有20ml蒸馏水的烧杯中,静置让其充分溶胀、溶解,形成甲基纤维素凝胶液,待用;d) take by weighing 0.07g of methylcellulose, add it to a beaker containing 20ml of distilled water, let it stand still to fully swell and dissolve, and form a methylcellulose gel solution for use;
e)称取聚乙烯醇0.40g,加入到装有30ml蒸馏水的烧杯中,95℃水浴加热,边加热边搅拌,静置让其充分溶胀、溶解,形成聚乙烯醇凝胶液,待用;e) Weigh 0.40 g of polyvinyl alcohol, add it to a beaker containing 30 ml of distilled water, heat in a 95°C water bath, stir while heating, let it stand still to fully swell and dissolve, and form a polyvinyl alcohol gel solution, ready for use;
f)五种凝胶液混合搅拌,形成均匀的凝胶基质,待用;f) five kinds of gel liquids are mixed and stirred to form a uniform gel matrix, which is ready for use;
g)分别量取海带提取液0.8ml、白芨提取液0.6ml、虫草花提取液1.2ml、薰衣草提取液1.0ml、草莓榨取液1.5ml、樱桃榨取液0.9ml、杨梅榨取液1.5ml置于烧杯中,搅拌均匀,形成溶液1,待用;g) Measure 0.8ml of kelp extract, 0.6ml of Bletilla striata extract, 1.2ml of cordyceps flower extract, 1.0ml of lavender extract, 1.5ml of strawberry extract, 0.9ml of cherry extract, and 1.5ml of bayberry extract, respectively, and place them in a beaker , stir evenly to form solution 1, ready to use;
h)称取烟酰胺0.6g,加入到装有6ml蒸馏水的烧杯中,静置让其充分溶解,形成烟酰胺溶液,待用;h) Weigh 0.6 g of nicotinamide, add it to a beaker containing 6 ml of distilled water, and let it be fully dissolved by standing to form a nicotinamide solution, which is ready for use;
i)称取海藻糖1.5g,装入烧杯中,加入12ml的蒸馏水,静置让其充分溶解,形成海藻糖溶液,待用;i) Weigh 1.5g of trehalose, put it into a beaker, add 12ml of distilled water, let it be fully dissolved by standing to form a trehalose solution, and stand by;
j)称取尼泊金乙酯0.2g,溶于75%乙醇2ml中,形成防腐剂溶液,待用;j) Weigh 0.2 g of ethyl paraben and dissolve it in 2 ml of 75% ethanol to form a preservative solution, ready for use;
k)称取奶粉1.2g,加蒸馏水8ml,搅拌溶解,形成牛奶溶液,待用;k) Weigh 1.2 g of milk powder, add 8 ml of distilled water, stir to dissolve, and form a milk solution for use;
l)将烟酰胺溶液、海藻糖溶液与牛奶溶液混合搅拌均匀,形成溶液2,待用;1) nicotinamide solution, trehalose solution and milk solution are mixed and stirred to form solution 2, for use;
m)分别向凝胶基质中加入溶液1、溶液2、防腐剂溶液、甘油1.5g、蜂蜜0.8g和牛奶香精0.08ml,搅拌均匀,即得细腻均匀嫩白滋润去角质淡化细纹手膜。m) Add solution 1, solution 2, preservative solution, glycerin 1.5g, honey 0.8g and milk essence 0.08ml to the gel matrix respectively, and stir well to obtain a delicate, uniform, whitening, moisturizing, exfoliating, and fine-wrinkle hand mask.
实施例3Example 3
一种嫩白滋润的手膜,含有以下配比的原料组分:A whitening and moisturizing hand mask, which contains the following raw material components:
3.1海带提取液的制备3.1 Preparation of kelp extract
称取海带60g,剪碎,加水煎煮提取3次:第1次加18倍量水提取2h;第2次加15倍量水,提取1.5h;第3次加10倍量水,提取1.5h,每次滤过得滤液,合并滤液,滤液的体积浓缩至海带重量的6倍g/ml,备用。Weigh 60g of kelp, cut it into pieces, add water to decoct and extract 3 times: the first time, add 18 times the amount of water to extract for 2 hours; the second time, add 15 times the amount of water, and extract for 1.5 hours; the third time, add 10 times the amount of water, and extract 1.5 hours. h, the filtrate is obtained by filtration each time, the filtrate is combined, and the volume of the filtrate is concentrated to 6 times the g/ml of the kelp weight, for subsequent use.
3.2白芨提取液的制备3.2 Preparation of Bletilla striata extract
称取白芨粗粉45g,用水浸泡0.75h,加热煎煮提取3次:第1次加16倍量水,提取2h;第2次加14倍量水,提取1.5h;第3次加11倍量水,提取1.0h,每次滤过得滤液,合并滤液,滤液的体积浓缩至白芨重量的6倍g/ml,备用。Weigh 45g of Bletilla striata coarse powder, soak in water for 0.75h, heat and decoct for 3 times: add 16 times the amount of water for the first time, extract for 2h; add 14 times the amount of water for the second time, extract for 1.5h; add 11 times the amount of water for the third time amount of water, extract for 1.0h, filter each time to obtain filtrate, combine the filtrates, and concentrate the volume of the filtrate to 6 times the weight of Bletilla striata g/ml, for later use.
3.3虫草花提取液的制备3.3 Preparation of Cordyceps Flower Extract
称取虫草花40g,用水浸泡0.7h,加热煎煮提取3次:第1次加20倍量水,提取2h;第2次加17倍量水,提取1.5h;第3次加15倍量水,提取1.0h,每次滤过得滤液,合并滤液,滤液的体积浓缩至虫草花重量的7倍g/ml,备用。Weigh 40 g of Cordyceps flower, soak it in water for 0.7 hours, and heat it for 3 times of extraction: add 20 times the amount of water for the first time, and extract for 2 hours; add 17 times the amount of water for the second time, and extract for 1.5 hours; add 15 times the amount of water for the third time. Water, extract for 1.0h, filter each time to obtain filtrate, combine the filtrates, and concentrate the volume of the filtrate to 7 times g/ml of the weight of the Cordyceps flower, for later use.
3.4薰衣草提取液的制备3.4 Preparation of Lavender Extract
称取薰衣草花40g,用75%乙醇浸泡1.0h,加热回流提取3次:第1次加20倍量75%乙醇,提取1.5h;第2次加16倍量75%乙醇,提取1.5h;第3次加11倍量75%乙醇,提取1.0h,每次滤过得滤液,合并滤液,将滤液的体积浓缩至薰衣草花重量的8倍g/ml,备用。Weigh 40 g of lavender flowers, soak them in 75% ethanol for 1.0 h, and extract by heating and refluxing for 3 times: for the first time, add 20 times the amount of 75% ethanol for 1.5 h; for the second time, add 16 times the amount of 75% ethanol for 1.5 h; Add 11 times the amount of 75% ethanol for the third time, extract for 1.0h, filter each time to obtain a filtrate, combine the filtrates, and concentrate the volume of the filtrate to 8 times g/ml of the weight of the lavender flower for use.
3.5草莓榨取液的制备3.5 Preparation of strawberry extract
称取草莓50g,加入18倍蒸馏水,置于榨汁机内榨汁,四层纱布过滤,置于离心机内3000rpm,离心15min,取上清液备用;Weigh 50 g of strawberries, add 18 times distilled water, place in a juicer to squeeze the juice, filter with four layers of gauze, place in a centrifuge at 3000 rpm, centrifuge for 15 min, and take the supernatant for later use;
3.6樱桃榨取液的制备3.6 Preparation of cherry extract
称取去籽樱桃45g,加入16倍蒸馏水,置于榨汁机内榨汁,四层纱布过滤,置于离心机内3000rpm,离心15min,取上清液备用;Weigh 45g of deseeded cherries, add 16 times distilled water, put them in a juicer to squeeze the juice, filter with four layers of gauze, put them in a centrifuge at 3000rpm, centrifuge for 15min, and take the supernatant for later use;
3.7杨梅榨取液的制备3.7 Preparation of bayberry extract
称取杨梅35g,加入15倍蒸馏水,置于榨汁机内榨汁,四层纱布过滤,置于离心机内3000rpm,离心15min,取上清液备用。Weigh 35 g of bayberry, add 15 times distilled water, put it in a juicer to squeeze the juice, filter with four layers of gauze, put it in a centrifuge at 3000 rpm, centrifuge for 15 min, and take the supernatant for later use.
3.8嫩白滋润去角质淡化细纹手膜的制备3.8 Preparation of whitening, moisturizing, exfoliating, and fine-wrinkle hand mask
a)称取羧甲基纤维素钠0.10g,加入到装有25ml蒸馏水的烧杯中,50℃水浴加热,边加热边搅拌,静置让其充分溶胀、溶解,形成羧甲基纤维素钠凝胶液,待用;a) Weigh 0.10 g of sodium carboxymethyl cellulose, add it to a beaker containing 25 ml of distilled water, heat in a water bath at 50°C, stir while heating, let it stand still to fully swell and dissolve, and form sodium carboxymethyl cellulose coagulation glue, ready to use;
b)称取海藻酸钠0.09g,加入到装有20ml蒸馏水的烧杯中,80℃水浴加热,边加热边搅拌,静置让其充分溶胀、溶解,形成均匀的海藻酸钠凝胶液,待用;b) Weigh 0.09 g of sodium alginate, add it to a beaker containing 20 ml of distilled water, heat it in a water bath at 80°C, stir while heating, let it stand still to fully swell and dissolve, and form a uniform sodium alginate gel solution. use;
c)称取羟丙基甲基纤维素0.12g,加入到盛有30ml蒸馏水的烧杯中,静置让其充分溶胀、溶解,形成羟丙基甲基纤维素凝胶液,待用;c) Weigh 0.12 g of hydroxypropyl methylcellulose, add it to a beaker containing 30ml of distilled water, let it stand still to fully swell and dissolve, and form a hydroxypropyl methylcellulose gel solution, which is ready for use;
d)称取甲基纤维素0.11g,加入到装有25ml蒸馏水的烧杯中,静置让其充分溶胀、溶解,形成甲基纤维素凝胶液,待用;d) Weigh 0.11 g of methylcellulose, add it to a beaker containing 25ml of distilled water, let it stand still to fully swell and dissolve, and form a methylcellulose gel solution for use;
e)称取聚乙烯醇0.55g,加入到装有35ml蒸馏水的烧杯中,100℃水浴加热,边加热边搅拌,静置让其充分溶胀、溶解,形成聚乙烯醇凝胶液,待用;e) Weigh 0.55g of polyvinyl alcohol, add it to a beaker containing 35ml of distilled water, heat in a water bath at 100°C, stir while heating, let it stand still to fully swell and dissolve to form a polyvinyl alcohol gel solution, set aside for use;
f)五种凝胶液混合搅拌,形成均匀的凝胶基质,待用;f) five kinds of gel liquids are mixed and stirred to form a uniform gel matrix, which is ready for use;
g)分别量取海带提取液1.5ml、白芨提取液1.0ml、虫草花提取液1.8ml、薰衣草提取液1.2ml、草莓榨取液1.8ml、樱桃榨取液1.8ml、杨梅榨取液2.0ml置于烧杯中,搅拌均匀,形成溶液1,待用;g) Measure 1.5ml of kelp extract, 1.0ml of Bletilla striata extract, 1.8ml of cordyceps flower extract, 1.2ml of lavender extract, 1.8ml of strawberry extract, 1.8ml of cherry extract, and 2.0ml of bayberry extract, respectively, and place them in a beaker , stir evenly to form solution 1, ready to use;
h)称取烟酰胺1.3g,加入到装有9ml蒸馏水的烧杯中,静置让其充分溶解,形成烟酰胺溶液,待用;h) Weigh 1.3 g of nicotinamide, add it to a beaker containing 9 ml of distilled water, and let it be fully dissolved by standing to form a nicotinamide solution for use;
i)称取海藻糖2.0g,装入烧杯中,加入15ml的蒸馏水,静置让其充分溶解,形成海藻糖溶液,待用;i) Weigh 2.0 g of trehalose, put it into a beaker, add 15 ml of distilled water, let it be fully dissolved by standing still to form a trehalose solution, and stand by;
j)称取尼泊金乙酯0.3g,溶于75%乙醇3ml中,形成防腐剂溶液,待用;j) Weigh 0.3 g of ethyl paraben and dissolve it in 3 ml of 75% ethanol to form a preservative solution, ready for use;
k)称取奶粉1.6g,加蒸馏水10ml,搅拌溶解,形成牛奶溶液,待用;k) Weigh 1.6g of milk powder, add 10ml of distilled water, stir to dissolve, form a milk solution, and stand by;
l)将烟酰胺溶液、海藻糖溶液与牛奶溶液混合搅拌均匀,形成溶液2,待用;1) nicotinamide solution, trehalose solution and milk solution are mixed and stirred to form solution 2, for use;
m)分别向凝胶基质中加入溶液1、溶液2、防腐剂溶液、甘油3.0g、蜂蜜1.1g和桂花香精0.08ml,搅拌均匀,即得细腻均匀嫩白滋润去角质淡化细纹手膜。m) Add solution 1, solution 2, preservative solution, glycerin 3.0g, honey 1.1g and sweet-scented osmanthus essence 0.08ml to the gel matrix respectively, and stir evenly to obtain a delicate, uniform, whitening, moisturizing, exfoliating, and fine-wrinkle hand mask.
实施例4Example 4
实施例1、2、3的理化指标如下:The physical and chemical indexes of embodiment 1,2,3 are as follows:
4.1性状4.1 Traits
本品为粘稠度适宜,细腻均匀,涂展性、成膜性良好的淡黄色膜剂。This product is a light yellow film agent with suitable viscosity, fine and uniform, good spreadability and film-forming property.
4.2pH值检查4.2 pH check
用润湿的pH试纸蘸取少量手膜,pH为6.5-7.5。Dip a small amount of hand mask with moistened pH paper, pH 6.5-7.5.
4.3冷热试验4.3 Hot and cold test
将膜剂封装于透明化妆品瓶中,于4℃的冰箱冷藏一周左右观察无分层现象。于55℃的恒温箱内放置24h,膜剂无分层乳化变味等现象。Encapsulate the film in a transparent cosmetic bottle, and refrigerate it in a refrigerator at 4°C for about a week to observe that there is no delamination phenomenon. When placed in a constant temperature box at 55°C for 24 hours, the film has no phenomena such as delamination, emulsification and odor.
4.4离心试验4.4 Centrifugal test
将手膜封装于具塞试管中3000r/min,离心20min,无分层现象。The hand mask was packaged in a stoppered test tube at 3000 r/min and centrifuged for 20 min without delamination.
4.5刺激性试验、过敏性实验4.5 Irritant test, allergy test
小白鼠背部剪去毛,分别涂抹按实施例1、2、3制备的手膜于剪去毛的部位,和没涂部位进行比较,结果没有刺激性和过敏反应。The back of the mice was cut and the hair was cut off, and the hand masks prepared according to Examples 1, 2 and 3 were respectively applied to the cut-off parts, and compared with the parts that were not coated, the results showed no irritation or allergic reaction.
取实施例膜剂涂于志愿者(16-70岁,60人)手面上,过30分钟后观察,均没出现发红、发疹、起泡现象。The film preparations of the examples were applied to the hands of volunteers (16-70 years old, 60 people), and observed after 30 minutes, no redness, rash and blistering were found.
4.6室温放置实验4.6 Experiment at room temperature
将实施例1、2、3所制的膜剂置于化妆品盒中,室温静置考察6个月,无分层现象,用后感觉无变化,气味无变化。The films prepared in Examples 1, 2, and 3 were placed in a cosmetic box, and stood at room temperature for 6 months. There was no delamination, no change in feeling and no change in smell after use.
4.7润肤效果4.7 Emollient effect
选取志愿者(16-70岁,60人),将所制得的手膜涂于志愿者手上,所形成的膜柔软细腻,成膜快,容易揭下,手感较好。用后手部皮肤感觉清爽滋润,光滑舒适。Select volunteers (16-70 years old, 60 people), apply the prepared hand film on the hands of the volunteers, the formed film is soft and delicate, the film is formed quickly, it is easy to remove, and the hand feel is good. Hand skin feels refreshed, moisturised, smooth and comfortable after use.
实施例5Example 5
该手膜综合效果考察Investigation of the comprehensive effect of the hand mask
以下利用试用感觉来评价实施例1、2、3制造出的手膜的功效。采用民意调查评分法,选取60名16-70岁年龄段的女性作为试用对象,任意等分成两组,分别用实施例1、2、3制备的手膜涂抹于手上。每周使用三次,使用时间为两个月。各项使用效果总分为5分:5分为最高分,表示很好,非常满意;4分为较好;3分为可以接受;3分以下为不好,不能接受。以下为各项平均得分。结果见表1:The efficacy of the hand masks produced in Examples 1, 2, and 3 is evaluated below by using the feeling of trial use. Using the opinion poll scoring method, 60 women aged 16-70 were selected as trial subjects, randomly divided into two groups, and the hand masks prepared in Examples 1, 2, and 3 were applied to their hands respectively. Use three times a week for two months. The total score of each use effect is 5 points: 5 points are the highest score, which means very good and very satisfied; 4 points are good; 3 points are acceptable; less than 3 points are bad and unacceptable. Below are the average scores for each item. The results are shown in Table 1:
表1综合效果考察Table 1 Comprehensive effect investigation
综上所述,本发明所制的手膜质地均匀细腻,气味芬芳,以天然植物提取物为主要有效成分,可以深层保护手部皮肤,达到滋养、美白、修复、抗衰老的效果,使手部肌肤嫩白、红润、有光泽,恢复年轻态。To sum up, the hand mask prepared by the present invention is even and delicate in texture, fragrant in smell, and uses natural plant extracts as the main effective components, which can deeply protect the skin of the hands, and achieve the effects of nourishing, whitening, repairing and anti-aging, so that the hands can be protected. The skin is whitened, rosy, radiant and youthful.
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