CN107669281A - Animal blood serum gathers test tube and serum separator - Google Patents

Abstract

The invention provides an animal serum collection test tube and a serum separator, which relate to the technical field of animal serum collection. The animal serum collection test tube provided by the invention includes a vacuum collection tube, a needle assembly and a filter tube, wherein: the needle assembly is arranged in the vacuum collection tube The opening at the top is detachably connected to the vacuum collection tube; the filter tube is set in the vacuum collection tube, and the blood inlet of the filter tube is connected to the needle assembly to receive the blood drawn from the needle assembly, and the filter tube is provided with a passage for serum microporous. The animal serum collection test tube does not need to transfer the serum sample twice when collecting the serum sample, simplifies the collection and detection process of the serum sample, and can reduce the probability of contamination of the serum sample.

Description

Animal serum collection test tube and serum separator

technical field

The invention relates to the technical field of animal serum collection, in particular to an animal serum collection test tube and a serum separator.

Background technique

When veterinary laboratory technicians monitor animals for immune antibodies, they usually need to collect animal serum samples. For the collection of serum samples, the following two methods are generally used:

Method 1: Blood is collected using a collection test tube, and then the blood sample is sent for inspection. After the blood sample is layered through a centrifuge, a veterinary lab technician uses a pipette or pipette to remove the serum and add it to a sample tube for storage or analysis.

Method 2: Blood is collected using a collection test tube, and then the blood sample is sent for inspection. After a period of tilting at a constant temperature, the blood samples are stratified, and then veterinary laboratory technicians use a pipette to suck out the serum and add it to a sample tube for storage or analysis.

Both of the above two methods require secondary transfer treatment of the serum, which makes the laboratory testing process very complicated, and the chance of contamination of the serum sample is also greater.

Therefore, how to provide an animal serum collection test tube and a serum separator that avoids the complicated process of laboratory technicians collecting serum samples and reduces the probability of contamination of serum samples is one of the technical problems to be solved by those skilled in the art.

Contents of the invention

The purpose of the present invention is to provide a test tube for collecting animal serum to solve the technical problems in the prior art that the process of collecting serum samples by veterinarians is complicated and the probability of contamination of serum samples is high. In addition, a serum separator using the above animal serum collection test tube is provided.

The invention provides an animal serum collection test tube, including a vacuum collection tube, a needle assembly and a filter tube, wherein:

The needle assembly is arranged at the opening at the top of the vacuum collection tube and is detachably connected to the vacuum collection tube;

The filter tube is set in the vacuum collection tube, and the blood inlet of the filter tube is connected to the top of the vacuum collection tube to receive the blood drawn from the needle assembly. micropores.

Further, the needle assembly includes a needle and a hose, one end of the hose is connected to the needle, and the other end of the hose is detachably connected to the top of the vacuum collection tube.

Further, the bottom of the filter tube is 2cm-3cm away from the bottom of the vacuum collection tube.

Further, the filter tube includes an upper tube body and a lower tube body, and the micropores are distributed in the lower tube body.

The present invention also provides a serum separator, which includes a housing, a rotating mechanism and the animal serum collection test tube described in the above proposal, the rotating mechanism is arranged inside the housing, and the rotating mechanism is provided with a plurality of The chute accommodates the animal serum collection test tube, and the rotating mechanism is used to drive the animal serum collection test tube to perform centrifugal motion.

Further, the rotating mechanism is provided with a power supply and a resistance wire for heating the animal serum collection test tube, and the power supply is electrically connected with the resistance wire.

Further, the resistance wire is embedded in the rotating mechanism and extends helically around the chute.

Further, the rotating mechanism is also provided with a temperature sensor and a controller, the controller is electrically connected to the temperature sensor and the resistance wire, and the temperature sensor is used to detect the heating temperature of the resistance wire and The temperature signal is sent to the controller, and the controller is used to receive the temperature signal and control the heating temperature of the resistance wire.

Further, the top of the housing is provided with an ultraviolet sterilizing device for sterilizing the animal serum collection test tube.

Further, it also includes a control panel arranged outside the housing, and the control panel is provided with buttons for switching the working state of the ultraviolet disinfection device.

The animal serum collection test tube provided by the invention can produce the following beneficial effects:

When using the above-mentioned animal serum collection test tube, the blood in the animal body is sucked into the filter tube through the use of the needle assembly and the vacuum collection tube first, and then the veterinarian can directly separate the blood, and the serum automatically enters the vacuum through the micropore during the separation process The space between the collection tube and the filter tube is collected at the bottom of the vacuum collection tube, and other substances in the blood remain in the filter tube, thereby achieving the purpose of separating serum.

In the animal serum collection test tube provided by the present invention, since the filter tube is provided with micropores for serum to pass through, after the separation is completed, the serum and other substances in the blood can be respectively accommodated at the bottom of the vacuum collection tube and the filter tube. When checking the serum, the needle assembly and the filter tube can be removed, and the serum in the vacuum collection tube can be directly tested. Compared with the prior art, the animal serum collection test tube provided by the present invention breaks away from the traditional idea that when blood is separated, the serum is suspended on the upper layer of the blood to realize the separation and collection of serum, but directly separates the serum into the vacuum collection tube At the bottom of the bottom, the serum is completely separated from other substances in the blood at one time, without the need for secondary transfer of the serum sample, which simplifies the collection and testing process of the serum sample, and at the same time reduces the probability of contamination of the serum sample.

The serum separator provided by the present invention includes a housing, a rotating mechanism and an animal serum collection test tube. The rotating mechanism in the housing is provided with a chute for accommodating the animal serum collection test tube. The rotating mechanism drives the animal serum collection test tube to perform centrifugal movement. During the process, the serum in the animal serum collection test tube can be collected at the bottom of the vacuum collection tube through the micropores on the filter tube, and other substances in the blood can be retained in the filter tube, so that the complete separation of serum can be achieved faster, and after separation There is no need to transfer the serum sample twice, which simplifies the collection and detection process of the serum sample.

Description of drawings

In order to more clearly illustrate the specific implementation of the present invention or the technical solutions in the prior art, the following will briefly introduce the accompanying drawings that need to be used in the specific implementation or description of the prior art. Obviously, the accompanying drawings in the following description The drawings show some implementations of the present invention, and those skilled in the art can obtain other drawings based on these drawings without any creative work.

Fig. 1 is a schematic structural view of an animal serum collection test tube provided in Example 1 of the present invention;

Fig. 2 is a schematic structural diagram of a serum separator provided in Example 2 of the present invention.

Icons: 1-vacuum collection tube; 2-needle assembly; 21-needle; 22-hose; 3-filter tube; 31-micropore; 4-housing; 5-rotation mechanism; 51-chute; 52-power supply ; 53-resistance wire; 54-temperature sensor; 55-controller; 6-ultraviolet disinfection device; 7-control panel; 71-button.

detailed description

The technical solutions of the present invention will be clearly and completely described below in conjunction with the accompanying drawings. Apparently, the described embodiments are some of the embodiments of the present invention, but not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer" etc. The indicated orientation or positional relationship is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the referred device or element must have a specific orientation, or in a specific orientation. construction and operation, therefore, should not be construed as limiting the invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and should not be construed as indicating or implying relative importance.

In the description of the present invention, it should be noted that unless otherwise specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection or a detachable connection. Connected, or integrally connected; it may be mechanically connected or electrically connected; it may be directly connected or indirectly connected through an intermediary, and it may be the internal communication of two components. Those of ordinary skill in the art can understand the specific meanings of the above terms in the present invention in specific situations.

Specific embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings. It should be understood that the specific embodiments described here are only used to illustrate and explain the present invention, not to limit the present invention.

Figure 1 is a schematic structural view of the animal serum collection test tube provided in Example 1 of the present invention; Figure 2 is a schematic structural view of the serum separator provided in Example 2 of the present invention.

Embodiment one:

The purpose of this embodiment is to provide a test tube for animal serum collection, as shown in Figure 1, comprising a vacuum collection tube 1, a needle assembly 2 and a filter tube 3, wherein: the needle assembly 2 is arranged at the opening on the top of the vacuum collection tube 1, And it is detachably connected with the vacuum collection tube 1; the filter tube 3 is arranged in the vacuum collection tube 1, and the blood inlet of the filter tube 3 is connected with the top of the vacuum collection tube 1 to receive the blood drawn from the needle assembly 2, and the filter tube 3 Micropores 31 are provided for passage of serum.

When using the above animal serum collection test tube, first use the needle assembly 2 and the vacuum collection tube 1 to suck the blood in the animal body into the filter tube 3, and then the veterinarian can directly separate the blood. During the separation process, the serum automatically passes through the micro The hole 31 enters the space between the vacuum collection tube 1 and the filter tube 3 and gathers at the bottom of the vacuum collection tube 1, and other substances in the blood remain in the filter tube 3, thereby achieving the purpose of separating serum.

In the animal serum collection test tube provided in this embodiment, since the filter tube 3 is provided with micropores 31 for serum to pass through, after the separation is completed, the serum and other substances in the blood can be contained in the vacuum collection tube 1 and the filter tube 3 respectively. When the serum needs to be checked, the needle assembly 2 can be removed and the filter tube 3 can be taken out at the same time, and the serum in the vacuum collection tube 1 can be tested directly. Compared with the prior art, the animal serum collection test tube provided by the present invention breaks away from the traditional idea that when blood is separated, the serum is suspended on the upper layer of the blood to realize the separation and collection of serum, but directly separates the serum into the vacuum collection tube The bottom of 1 realizes the complete separation of serum and other substances in blood at one time, without the need for secondary transfer of serum samples, which simplifies the collection and testing process of serum samples, and at the same time reduces the probability of contamination of serum samples.

The vacuum collection tube 1 is in a negative pressure state before use. When the needle assembly 2 is connected to the vacuum collection tube 1 for blood collection, the blood will be automatically absorbed into the filter tube 3 due to the negative pressure.

Therefore, any collection tube that can achieve the above effects can be used as the vacuum collection tube 1 provided in this embodiment.

In this embodiment, the vacuum collection tube 1 includes a shell and a cover body, the cover body is detachably connected to the shell body, and the blood inlet of the filter tube 3 is detachably connected to the cover body. When it is necessary to take out the filter tube in the vacuum collection tube 1 3, the filter tube 3 can be taken out from the vacuum collection tube 1 through the cover. Specifically, the connection between the cover and the housing, and between the blood inlet of the filter tube 3 and the cover may be screwed, clamped, or the like.

It should be noted that it is advisable that the diameter of the micropore 31 can just pass through the serum, the minimum diameter of the remaining substance in the blood after removing the serum is about 8 μm, and the diameter of the micropore 31 can be 5-7 μm. Specifically, in this embodiment , the diameter of the microhole 31 is 7 μm.

Further, in order to facilitate the collection of animal blood, as shown in FIG. Detachable connection. When blood collection is required, the needle 21 can be connected to the vacuum collection tube 1 through the flexible pipe 22. At this time, the negative pressure gas inside the vacuum collection tube 1 communicates with the outside world. At this time, the needle 21 is inserted into the blood vessel in the animal body. The blood will flow through the needle 21 through the hose 22 and then enter the filter tube 3, which is convenient for the veterinary blood collection process; before or after the blood collection, in order to facilitate the storage and transfer of the vacuum collection tube 1, the hose 22 can be Remove from vacuum collection tube 1.

Further, in order to more completely separate the serum from other substances in the blood, the bottom of the filter tube 3 is 2cm-3cm away from the bottom of the vacuum collection tube 1, so that the separated serum does not come into contact with the filter tube 3. Specifically, 2cm, 2.5cm, 3cm, etc. In this embodiment, the bottom of the filter tube 3 is 2.5cm away from the bottom of the vacuum collection tube 1. During the separation process, the serum is thrown onto the inner wall of the vacuum collection tube 1 through the micropore 31 under the action of centrifugal force, and then is gathered at the bottom of the vacuum collection tube 1 by gravity. There is a certain distance, so when the serum is separated, there is still a certain distance between the liquid level of the serum and the bottom of the filter tube 3, so as to achieve the purpose of completely separating the serum.

Further, in order to facilitate the production and processing of the filter tube 3, the filter tube 3 includes an upper tube body and a lower tube body, and micropores 31 are distributed in the lower tube body. When the blood enters the filter tube 3, the blood is contained in the lower tube body of the filter tube 3, and the micropores 31 are distributed in the lower tube body to avoid unnecessary processing of the filter tube 3, while ensuring that the serum is separated to the bottom of the vacuum collection tube 1.

Specifically, the inner wall of the filter tube 3 can be coated with reagents for accelerating serum separation, such as coagulant, lithium heparin anticoagulant, and the like.

Embodiment two:

The purpose of this embodiment is to provide a serum separator. As shown in Figure 2, the serum separator provided in the second embodiment includes a housing 4, a rotating mechanism 5 and the animal serum collection test tube provided in the first embodiment above, and the rotating mechanism 5 is located inside the housing 4, and the rotating mechanism 5 is provided with a plurality of chutes 51 for accommodating animal serum collection test tubes, and the rotating mechanism 5 is used to drive the animal serum collection test tubes to perform centrifugal movement.

The serum separator provided in this embodiment includes a housing 4, a rotating mechanism 5 and an animal serum collection test tube. The rotating mechanism 5 in the housing 4 is provided with a chute 51 for accommodating the animal serum collection test tube. During the centrifugal movement of the animal serum collection test tube, the serum in the animal serum collection test tube can gather at the bottom of the vacuum collection tube 1 through the micropore 31 on the filter tube 3, and other substances in the blood can be retained in the filter tube 3, The complete separation of serum can be achieved faster, and there is no need to transfer the serum sample again after separation, which simplifies the collection and detection process of serum samples.

Specifically, the rotating mechanism 5 may be provided with two, three, four, five or six chutes 51 for accommodating the animal serum collection test tubes. In this embodiment, the rotating mechanism 5 is provided with Four chutes 51 .

Wherein, the rotating mechanism 5 can be various structures that can drive the animal serum collection test tube to perform centrifugal motion, such as a rotating support connected to a motor drive, and the rotating mechanism 5 can also be a linear drive device such as a hydraulic cylinder or an air cylinder connected to the transmission mechanism. The mechanism for converting linear motion into rotary motion, in short, the specific structure of the rotating mechanism 5 can be varied, and this embodiment does not list them all here.

Preferably, the rotating mechanism 5 may include a first power supply, a motor and a rotating support, the chute 51 is arranged on the rotating support, the first power supply provides power for the motor, and the motor is connected to the rotating support in a transmission manner. Drive the rotating support to rotate, so that the animal serum collection test tube in the chute 51 can do centrifugal movement.

Further, in order to make the animal serum collection test tube more practical, the rotating mechanism 5 is provided with a power supply 52 and a resistance wire 53 for heating the animal serum collection test tube, and the power supply 52 is electrically connected to the resistance wire 53 . When the veterinarian separates serum under constant temperature and static conditions, the animal serum collection test tube can be placed in the chute 51 first, and the power supply is turned on to make the resistance wire 53 heat up, so that the temperature in the animal serum collection test tube is stabilized at 20°C-25°C. To ensure the normal separation of the serum, during the placing process, since the serum can flow into the bottom of the vacuum collection tube 1 through the micropore 31, after standing still for a certain period of time, the serum can be completely separated from other substances in the blood.

Specifically, in order to make the above two separation methods independent of each other, the power supply 52 can be arranged on the rotating support. When the serum is separated by centrifugation, the power supply 52 can rotate synchronously with the rotating support, and the power supply 52 is in an off state; The resistance wire generates heat, so that the temperature in the animal serum collection test tube is stabilized at 20°C-25°C.

Further, in order to allow the vacuum collection tube 1 to be heated more evenly, the resistance wire 53 is embedded in the rotating mechanism 5 and extends helically around the chute 51 . The resistance wire embedded in the rotating mechanism 5 can make the heat generated by the resistance wire evenly transferred to the vacuum collection tube 1 through the rotation mechanism 5, avoiding direct contact between the resistance wires and the vacuum collection tube 1, and preventing the vacuum collection tube from 1. The local temperature of the tube wall that is in direct contact with the resistance wire is too high, while the local temperature of the tube wall that is not in direct contact with the resistance wire is too low, which affects the separation effect. The resistance wire extends spirally around the chute 51 so that the resistance wire can heat the vacuum collection tube 1 more comprehensively.

On the basis of the above embodiments, due to the high temperature in summer, the indoor temperature may be higher than 25°C. In order to ensure that the temperature in the animal serum collection test tube is stable at 20°C-25°C, the rotating mechanism 5 can also be equipped with a refrigeration device. The refrigerating device can adopt multiple methods, such as a fan blowing 20°C-25°C cold air into the housing 4, or it can be a cooling pipe arranged on the chute 51, and 20°C-25°C air can be introduced into the cooling pipe. Gas or liquid, in short, any structure that can ensure that the temperature in the animal serum collection test tube is stable at 20°C-25°C can be the refrigeration device provided in this embodiment.

Further, in order to make the serum separator provided by this embodiment more intelligent, a temperature sensor 54 and a controller 55 are also provided on the rotating mechanism 5, and the controller 55 is electrically connected to the temperature sensor 54 and the resistance wire 53 respectively, and the temperature The sensor 54 is used for detecting the heating temperature of the resistance wire 53 and sending the temperature signal to the controller 55 , and the controller 55 is used for receiving the temperature signal and controlling the heating temperature of the resistance wire 53 . When the temperature in the animal serum collection test tube is between 20°C and 25°C, the controller 55 controls the resistance wire 53 to cancel the heating; when the temperature in the animal serum collection test tube is less than 20°C, the controller 55 controls the resistance wire 53 to perform Heating, no need for veterinarians to detect the temperature in the animal serum collection test tube in real time.

Specifically, the refrigeration device is electrically connected to the controller 55. When the temperature in the animal serum collection test tube is higher than 25°C, the controller 55 controls the refrigeration device to cool down, so as to better ensure the temperature in the animal serum collection test tube.

Further, in order to make the animal serum collection test tube reusable, the top of the housing 4 can be provided with an ultraviolet disinfection device 6 for sterilizing the animal serum collection test tube. When the animal serum collection test tube is used up once, the veterinarian can The animal serum collection test tube is initially disinfected and cleaned, and then the animal serum collection test tube can be placed in the chute 51, and the ultraviolet disinfection device 6 on the top of the housing 4 can sterilize and sterilize the animal serum collection test tube.

Specifically, the ultraviolet disinfection device 6 can be used to sterilize the part of the animal serum collection test tube, specifically the vacuum collection tube 1 and the filter tube 3, and the needle assembly 2 can be replaced with a new one every time it is used.

Further, in order to facilitate the veterinarian to control the working state of the ultraviolet disinfection device 6, the animal serum collection test tube provided in this embodiment also includes a control panel 7 arranged outside the housing 4, and the control panel 7 is provided with a switch for switching the ultraviolet disinfection device. 6 buttons 71 in working state. When the lower end of the button 71 is pressed, the ultraviolet disinfection device 6 works normally; when the upper end of the button 71 is pressed, the ultraviolet disinfection device 6 stops working.

Specifically, the control panel 7 is also provided with a first button for switching the working state of the rotating mechanism 5. When the lower end of the first button is pressed, the rotating mechanism 5 rotates; when the upper end of the first button is pressed, the rotating mechanism 5 stops. turn.

Specifically, in order to facilitate the veterinarian to know the temperature in the animal serum collection test tube in real time, the control panel 7 is also provided with a display screen for displaying the heating temperature of the resistance wire.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present invention, rather than limiting them; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: It is still possible to modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements for some or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the technical solutions of the various embodiments of the present invention. scope.

Claims (10)

1. An animal serum collection test tube is characterized in that it comprises a vacuum collection tube (1), a needle assembly (2) and a filter tube (3), wherein: The needle assembly (2) is arranged at the opening at the top of the vacuum collection tube (1), and is detachably connected to the vacuum collection tube (1); The filter tube (3) is arranged in the vacuum collection tube (1), and the blood inlet of the filter tube (3) is connected to the top of the vacuum collection tube (1) to receive the needle assembly ( 2) For the drawn blood, the filter tube (3) is provided with micropores (31) for serum to pass through. 2. animal serum collection test tube according to claim 1, is characterized in that, described needle assembly (2) comprises needle (21) and flexible pipe (22), and one end of described flexible pipe (22) is connected with described needle (21) connection, the other end of the flexible pipe (22) is detachably connected to the top of the vacuum collection tube (1). 3. The animal serum collection test tube according to claim 1, characterized in that the bottom of the filter tube (3) is 2cm-3cm away from the bottom of the vacuum collection tube (1). 4. The animal serum collection test tube according to claim 1, characterized in that, the filter tube (3) comprises an upper tube body and a lower tube body, and the micropores (31) are distributed in the lower tube body. 5. A serum separator, characterized in that it comprises a housing (4), a rotating mechanism (5) and the animal serum collection test tube according to any one of claims 1-4, the rotating mechanism (5) is set Inside the housing (4), the rotating mechanism (5) is provided with a plurality of chutes (51) for accommodating the animal serum collection test tubes, and the rotating mechanism (5) is used to drive the Animal serum collection test tubes are centrifuged. 6. The serum separator according to claim 5, characterized in that, the rotating mechanism (5) is provided with a power supply (52) and a resistance wire (53) for heating the animal serum collection test tube, so that The power supply (52) is electrically connected to the resistance wire (53). 7. The serum separator according to claim 6, characterized in that, the resistance wire (53) is embedded inside the rotating mechanism (5) and extends helically around the chute (51). 8. The serum separator according to claim 6, characterized in that, the rotating mechanism (5) is also provided with a temperature sensor (54) and a controller (55), and the controller (55) is connected with the The temperature sensor (54) is electrically connected to the resistance wire (53), and the temperature sensor (54) is used to detect the heating temperature of the resistance wire (53) and send the temperature signal to the controller (55) , the controller (55) is used for receiving the temperature signal and controlling the heating temperature of the resistance wire (53). 9. The serum separator according to claim 5, characterized in that, the top of the housing (4) is provided with an ultraviolet sterilizing device (6) for sterilizing the animal serum collection test tube. 10. The serum separator according to claim 9, characterized in that, it also comprises a control panel (7) arranged on the outside of the housing (4), and the control panel (7) is provided with a switch for switching the The button (71) of the working state of the ultraviolet disinfection device (6).