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CN107617051A - A kind of medicine for hemorrhoid treating - Google Patents

A kind of medicine for hemorrhoid treating Download PDF

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Publication number
CN107617051A
CN107617051A CN201710895166.8A CN201710895166A CN107617051A CN 107617051 A CN107617051 A CN 107617051A CN 201710895166 A CN201710895166 A CN 201710895166A CN 107617051 A CN107617051 A CN 107617051A
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CN
China
Prior art keywords
parts
medicine
hemorrhoid
hemorrhoid treating
vaseline
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CN201710895166.8A
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Chinese (zh)
Inventor
张洪林
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Individual
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Individual
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Priority to CN201710895166.8A priority Critical patent/CN107617051A/en
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Abstract

The invention provides a kind of medicine for hemorrhoid treating, the medicine includes:50 150 parts of 3 parts of activated carbon, 0.5 1 parts of the bletilla striata, 0.4 0.6 parts of borneol, 0.4 0.5 parts of peppermint oil, 0.6 1 parts of cow-bezoar, 0.6 1 parts of Resina Draconis, 0.3 0.5 parts of pearl powder, 0.5 1 parts of calamine and vaseline.The hemorrhoid treating medicine of the present invention has the function that anti-inflammatory, detumescence, stagnation resolvation, analgesic, promotes the elimination of blood backflow and swollen tissue.Each Chinese medicine included in the medicine can effectively treat hemorrhoid and recurrence rate is significantly lower than commercially available prod by being mixed and made into suppository or ointment after crushing, grinding.

Description

A kind of medicine for hemorrhoid treating
Technical field
The present invention relates to medical Instrument field, and in particular to a kind of medicine for hemorrhoid treating.
Background technology
Hemorrhoid are a kind of common diseases positioned at anus area, and any age can all fall ill, but with age, morbidity Rate gradually increases.In China, hemorrhoid are most common anorectal diseases, are known as " ten male nine hemorrhoid ", the saying of " hemorrhoid of ten female ten ".
Hemorrhoid main cause is presently considered to be varicosis of hemorrhoidal vein, inflammatory tissue lesion, haemorrhoidal vein thrombosis and connective group Knit hyperplasia and anus pad moves down.
At present, the treatment to hemorrhoid is mainly using three kinds of medicament fumigating, drug coat and operative treatment modes.
But effect of the medicament fumigating equipment to hemorrhoid belongs to indirectly-acting, effect is limited, therefore, enters in this way Often time-consuming, curative effect is slow, utilization ratio of drug is low for row treatment.And because medicament fumigating generally requires to set using the stifling of benzvalene form Standby, equipment size is big, inconvenient for use, it is impossible to directly acts on diseased region.
Although operative treatment can eradicate haemorrhoids, normal structure is damaged, causes the stricture of anus, influences bowel movement function, Painful big, the recovery cycle length brought to patient.
The mode of medicine coating is although quick, and effect is good, but is typically only capable to play interim analgesia detumescence effect, medicine Thing is once stopped using, and is easily recurred.
Therefore, the mode or equipment treated in currently available technology to hemorrhoid have the defects of it is difficult to overcome.People It is highly desirable have it is a kind of can to hemorrhoid carry out long-acting treatment medicine.
The content of the invention
In view of the above-mentioned problems, the invention provides a kind of medicine for hemorrhoid treating, it is characterised in that the medicine bag Include:Activated carbon, the bletilla striata, borneol, peppermint oil, cow-bezoar, Resina Draconis, pearl powder, calamine and vaseline.
In a kind of preferred implementation, the medicine also includes:Dysosma versipellis, catharanthus roseus, black nightshade, bittersweet, Rabdosia rubescens with And Chinese small iris.
In another preferred implementation, the medicine includes 3 parts of activated carbon, bletilla striata 0.5-1 parts, borneol 0.4-0.6 Part, peppermint oil 0.4-0.5 parts, cow-bezoar 0.6-1 parts, Resina Draconis 0.6-1 parts, pearl powder 0.3-0.5 parts, calamine 0.5-1 parts with And vaseline 50-150 parts.
In another preferred implementation, the medicine includes 3 parts of activated carbon, bletilla striata 0.5-1 parts, borneol 0.4-0.6 Part, peppermint oil 0.4-0.5 parts, cow-bezoar 0.6-1 parts, Resina Draconis 0.6-1 parts, pearl powder 0.3-0.5 parts, calamine 0.5-1 parts, 50 parts of vaseline, Dysosma versipellis 0.4-0.6 parts, catharanthus roseus 0.3-0.5 parts, black nightshade 0.3-0.5 parts, bittersweet 0.4-0.6 parts, winter insult Careless 0.4-0.6 parts and the sub- 0.4-0.6 parts of Chinese small iris.
In another preferred implementation, the medicine is suppository, and each Chinese medicine included in the medicine leads to Cross crushing, grinding is mixed and made into suppository afterwards or paste (being fitted into the similar syringe-like structure with urging means).
In another preferred implementation, the medicine also includes the special formulation for special population.
On the other hand the present invention provides a kind of method for preparing hemorrhoid treating medicine, it is characterised in that methods described includes The raw material of above-mentioned each Chinese medicine is crushed, grinding, at least part in Chinese medicine is either subjected to water extraction or alcohol extracting, so The powder obtained or water extract or alcohol extract are mixed afterwards, suppository character is made.
The hemorrhoid treating medicine of the present invention has the function that anti-inflammatory, detumescence, stagnation resolvation, analgesic, promotes blood backflow and tissue The elimination of swelling.
Embodiment
Present applicant devises standard type, height when researching and developing hemorrhoid treating medicine for different user crowds End type and tailored version, for common ordinary consumer, plain edition medicine can be used, it is more for high-end user, addition Chinese medicine simultaneously contains some and treasures medicinal material, therefore cost is higher.And for some high requests user, tailored version medicine can be used Thing.
Embodiment 1
In the present embodiment, the medicine for hemorrhoid treating is made of following raw materials:Activated carbon 30g, bletilla striata 6g, borneol 5g, peppermint oil 5g, cow-bezoar 7g, Resina Draconis 8g, pearl powder 4g, calamine 8g and vaseline 100g,
The above-mentioned raw material in addition to vaseline is shredded respectively, pulverizes and mixes, then mix drug powder Thing is bound together with vaseline, is stirred, and ointment is made, or enclose in the packaging of predetermined shape and suppository or cream is made Agent.
In a kind of preferable preparation method, in the case of extensive prepare, by the amount of above-mentioned prepared Chinese medicine 100 times of increase is added in extractor (except activated carbon and vaseline), and ethanol solution is added in extractor;
In extractor is carried out to the Chinese medicine prepared the alcohol extracting scheduled time;
Mixture in the extractor is filtered, pulls the dregs of a decoction out, obtains alcohol extract;
The alcohol extract be concentrated under reduced pressure and obtains corresponding Part I thick medicinal extract, and reclaims ethanol;
The dregs of a decoction are placed again into extractor, add pure water, heating decocts 20-30 minutes, filters again, discard the dregs of a decoction, Aqueous extracts are concentrated under reduced pressure, obtain Part II thick medicinal extract;
Mixing is carried out to two parts thick medicinal extract to be dried in vacuo, and obtains dry extract;
The dry extract is crushed and sieved, obtains extract extract powder;
By activated carbon drying and crushing, after being mixed with extract extract powder, it is bound together, stirs with vaseline;
The product obtained is dispensed into sebific duct or disposable suppository shell, suppository shell can use soluble gelatin or Other soluble materials are made.
Embodiment 2
In the present embodiment, the medicine for hemorrhoid treating is made of following raw materials:Activated carbon 30g, bletilla striata 6g, borneol 5g, peppermint oil 5g, cow-bezoar 7g, Resina Draconis 8g, pearl powder 4g, calamine 8g, vaseline 100g, Dysosma versipellis 5g, catharanthus roseus 4g, dragon Certain herbaceous plants with big flowers 4g, bittersweet 5g, Rabdosia rubescens 5g and the sub- 5g of Chinese small iris.
The above-mentioned raw material in addition to vaseline is shredded respectively, pulverizes and mixes, then mix drug powder Thing is bound together with vaseline, is stirred, and ointment is made, or enclose in the packaging of predetermined shape and suppository is made.
In the case of extensive prepare, the amount of above-mentioned prepared Chinese medicine is increased 100 times and adds extractor (activity Except charcoal and vaseline) in, and ethanol solution is added in extractor;
In extractor is carried out to the Chinese medicine prepared the alcohol extracting scheduled time;
Mixture in the extractor is filtered, pulls the dregs of a decoction out, obtains alcohol extract;
The alcohol extract be concentrated under reduced pressure and obtains corresponding Part I thick medicinal extract, and reclaims ethanol;
The dregs of a decoction are placed again into extractor, add pure water, heating decocts 30-120 minutes, filters again, discard the dregs of a decoction, Aqueous extracts are concentrated under reduced pressure, obtain Part II thick medicinal extract;
Mixing is carried out to two parts thick medicinal extract to be dried in vacuo, and obtains dry extract;
The dry extract is crushed and sieved, obtains extract extract powder;
By activated carbon drying and crushing, after being mixed with extract extract powder, it is bound together, stirs with vaseline;
The product obtained is dispensed into sebific duct or disposable suppository shell, suppository shell can use soluble gelatin or Other soluble materials are made.
For medicine prepared in example 1 above and 2, (medicine used is the preparation side of extract mixing vaseline Prepared by formula, the preparation method directly crushed is although simple and easy, but drug effect is not so good as extract mode), applicant is respectively with paste Form, clinical patients are tested.Moderate hemorrhoid patients 60 are chosen respectively, and every 20 are one group, and it is real to impose (1) respectively Apply the medicine in example 1, the medicine in (2) embodiment 2, (3) commercially available Ma Yinglong boards acne cream.
Specific experiment result is as follows:
From contrast above as can be seen that medicine prepared by the present invention is not only higher than commercially available horse in terms of cure rate answers Imperial board Suppository for treatment of pile, and the recurrence rate in 3 months will be significantly lower than Ma Yinglong board acne creams.Especially high-end of the invention Product, the recurrence rate in 3 months are less than other commercially available prod.
Embodiment 3
Although the product of upper surface compositions has been able to realize preferable effect in cure rate and recurrence rate control aspect, Be, upper surface compositions primarily directed to it is light, moderate patient outcome is preferable, but for severe patient, due to severe patient's meeting There is situations such as anal fissure, anal fistula, or even the anal sphincter of some patients shrinks hypotaxia, can go out for the confining force of medicine Now weaken.If medicine is made suppository and fills in or squeeze into patient anus, patient's awareness of defecation strengthens additional hypotaxia.Medicine can be along Anus outwards overflows.
Therefore, applicant is directed to such PATIENT POPULATION and devises a kind of slow-release medicine carrying bolt, medicine carrying bolt Including:First soluble integument, the second medicine layer, the 3rd drawn grain contact layer, drug core, the first soluble integument is normal The cylindric soluble material of rule is made, such as, very thin one layer is made in edible gelatin etc., the first soluble integument, is located at Outermost layer.Second medicine layer is set in soluble integument, so after soluble integument dissolves, medicine can discharge, Pain easing and hemostasis is carried out to the haemorrhoids of patient, the 3rd drawn grain contact layer is made up of flexible rubber or silica gel, and surface has a large amount of folds, The boss of fold can play a part of massage to haemorrhoids, be provided with some holes at fold chase, in drawn grain contact layer Portion is embedded in medicine.It is the medicament in embodiment 2 in the present embodiment, used by the second medicine layer and drug core, this Kind pharmacy effect is good.The product of the present embodiment is also mainly used in high-end customer.
Present applicant, the medicine of the present embodiment of the present invention is again divided into by two batches patient is tested, often The people of patient 20 is criticized, these patients are old anal fissure, the anal fistula patient of more than 60 years old, after medication, because sphincter is degenerated, commonly There can be a certain degree of medicine outflow after mode medication.
Administered by suppository is respectively adopted in two batches patient, and first patient is using soluble bolt shell (similar capsule shape Shape, long 2cm, diameter 0.8cm), second batch patient carries bolt using the spacetabs type in the present embodiment, in order to ensure dose phase Together, it is longer 0.3cm than soluble bolt shell to carry bolt length.
After patient medication, paper handkerchief is clamped at anus, to verify that medicine flows out situation.Found after contrast
It can be seen that slow-release suppository of the invention can effectively suppress the spilling of medicine, strengthen therapeutic effect.
Those skilled in the art are it should also be understood that above-described embodiment is also only the exemplary implementation to the present invention Explain, not limiting the scope of the present invention.

Claims (7)

1. a kind of medicine for hemorrhoid treating, it is characterised in that the medicine includes:Activated carbon, the bletilla striata, borneol, peppermint oil, Cow-bezoar, Resina Draconis, pearl powder, calamine and vaseline.
2. the medicine according to claim 1 for hemorrhoid treating, it is characterised in that the medicine also includes:Dysosma versipellis, Catharanthus roseus, black nightshade, bittersweet, Rabdosia rubescens and Chinese small iris.
3. the medicine according to claim 1 for hemorrhoid treating, it is characterised in that the medicine include 3 parts of activated carbon, Bletilla striata 0.5-1 parts, borneol 0.4-0.6 parts, peppermint oil 0.4-0.5 parts, cow-bezoar 0.6-1 parts, Resina Draconis 0.6-1 parts, pearl powder 0.3-0.5 parts, calamine 0.5-1 parts and vaseline 50-150 parts.
4. the medicine according to claim 2 for hemorrhoid treating, it is characterised in that the medicine include 3 parts of activated carbon, Bletilla striata 0.5-1 parts, borneol 0.4-0.6 parts, peppermint oil 0.4-0.5 parts, cow-bezoar 0.6-1 parts, Resina Draconis 0.6-1 parts, pearl powder 0.3-0.5 parts, calamine 0.5-1 parts, vaseline 50-150 parts, Dysosma versipellis 0.4-0.6 parts, catharanthus roseus 0.3-0.5 parts, black nightshade 0.3-0.5 parts, bittersweet 0.4-0.6 parts, Rabdosia rubescens 0.4-0.6 parts and the sub- 0.4-0.6 parts of Chinese small iris.
5. the medicine according to claim 1 or 2 for hemorrhoid treating, it is characterised in that the medicine is suppository, described Each Chinese medicine included in medicine after crushing, grinding by being mixed and made into suppository.
6. the medicine according to claim 1 or 2 for hemorrhoid treating, it is characterised in that the medicine also includes being used for The special formulation of special population.
A kind of 7. method for preparing hemorrhoid treating medicine, it is characterised in that methods described includes will be each in claim 1 or 2 The raw material of Chinese medicine is crushed, grinding, and at least part in Chinese medicine either is carried out into water extraction or alcohol extracting, then will be obtained Powder or water extract or alcohol extract mix, paste or suppository is made.
CN201710895166.8A 2017-09-28 2017-09-28 A kind of medicine for hemorrhoid treating Pending CN107617051A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710895166.8A CN107617051A (en) 2017-09-28 2017-09-28 A kind of medicine for hemorrhoid treating

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710895166.8A CN107617051A (en) 2017-09-28 2017-09-28 A kind of medicine for hemorrhoid treating

Publications (1)

Publication Number Publication Date
CN107617051A true CN107617051A (en) 2018-01-23

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Country Status (1)

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0840919A (en) * 1994-05-27 1996-02-13 Kureha Chem Ind Co Ltd Hemorrhoid disease medicine
CN1117847A (en) * 1994-05-27 1996-03-06 吴羽化学工业株式会社 Pharmaceutical composition for treating hemorrhoidal diseases
CN1403098A (en) * 2002-10-18 2003-03-19 武汉马应龙药业集团股份有限公司 Ointment for treating piles and other anorectal diseases and its prepn
CN1403142A (en) * 2002-10-18 2003-03-19 武汉马应龙药业集团股份有限公司 Suppository for treating piles and other anorectal diseases and its prepn
CN102008431A (en) * 2010-11-18 2011-04-13 沈阳亿灵医药科技有限公司 Double-layer moxifloxacin suppository and preparation method thereof
CN102198205A (en) * 2011-04-28 2011-09-28 上海市金山区中心医院枫泾分院 Lianzhi powder and preparation method thereof
CN102335343A (en) * 2011-10-10 2012-02-01 南京中医药大学 Chinese medicinal composition for treating haemorrhoids, and preparation method and application thereof
CN205460426U (en) * 2016-03-11 2016-08-17 德国葛芙制药有限公司 Be difficult for deviating from and alienable intestinal bolt

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0840919A (en) * 1994-05-27 1996-02-13 Kureha Chem Ind Co Ltd Hemorrhoid disease medicine
CN1117847A (en) * 1994-05-27 1996-03-06 吴羽化学工业株式会社 Pharmaceutical composition for treating hemorrhoidal diseases
CN1403098A (en) * 2002-10-18 2003-03-19 武汉马应龙药业集团股份有限公司 Ointment for treating piles and other anorectal diseases and its prepn
CN1403142A (en) * 2002-10-18 2003-03-19 武汉马应龙药业集团股份有限公司 Suppository for treating piles and other anorectal diseases and its prepn
CN102008431A (en) * 2010-11-18 2011-04-13 沈阳亿灵医药科技有限公司 Double-layer moxifloxacin suppository and preparation method thereof
CN102198205A (en) * 2011-04-28 2011-09-28 上海市金山区中心医院枫泾分院 Lianzhi powder and preparation method thereof
CN102335343A (en) * 2011-10-10 2012-02-01 南京中医药大学 Chinese medicinal composition for treating haemorrhoids, and preparation method and application thereof
CN205460426U (en) * 2016-03-11 2016-08-17 德国葛芙制药有限公司 Be difficult for deviating from and alienable intestinal bolt

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
邹爱玲等: "肛痛痔愈膏的制备", 《中成药》 *

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Application publication date: 20180123