CN107519406A - Strengthening spleen, tonifying kidney composition and preparation method thereof - Google Patents
Strengthening spleen, tonifying kidney composition and preparation method thereof Download PDFInfo
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- CN107519406A CN107519406A CN201710773098.8A CN201710773098A CN107519406A CN 107519406 A CN107519406 A CN 107519406A CN 201710773098 A CN201710773098 A CN 201710773098A CN 107519406 A CN107519406 A CN 107519406A
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- strengthening spleen
- tonifying kidney
- kidney composition
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- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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Abstract
The present invention discloses a kind of strengthening spleen, tonifying kidney composition and preparation method thereof, wherein, the strengthening spleen, tonifying kidney composition is made up of the raw material of following mass parts：150~180 parts of 90~110 parts of the fruit of Chinese wolfberry, 110~130 parts of mulberry fruit, 90~110 parts of sealwort, 90~110 parts of dark plum processed, 90~110 parts of radix polygonati officinalis, 90~110 parts of hawthorn, 70~90 parts of oyster, 70~90 parts of spina date seed, 90~110 parts of raspberry, 90~110 parts of lily, 90~110 parts of jujube, 90~110 parts of the root of kudzu vine, 110~130 parts of Chinese yam and corn stigma.Strengthening spleen, tonifying kidney composition provided by the invention is mixed by kinds of traditional Chinese medicines, and sugar content is low, is beneficial to diabetic's use.
Description
Technical field
The present invention relates to food processing technology field, and in particular to a kind of strengthening spleen, tonifying kidney composition and preparation method thereof.
Background technology
In recent years, the disease such as diabetes, hypertension and hyperlipidemia rises rapidly, and such disease is considered as and diet style
Closely related, prior art is proved in terms of can preventing this kind of disease by improving dietetic life.Diabetes (Diabetes
Mellitus, DM) by the caused endocrine metabolism using hyperglycaemia as common trait of the insulin reduction of pancreatic beta cell secretion
Disorder disease, it is referred to as " diabete " in the traditional Chinese medical science.Diabetes are often accompanied by serious complication, have a strong impact on diabetic's
Life.
Because the blood-sugar content in diabetic's body is unstable, it is necessary to Tighter control, the higher food of general sugar
Product are it is not recommended that edible.And the existing food lacked on the market with certain curative effect effect and suitable for patients with diabetes mellitus.
It is therefore desirable to provide a kind of food for adapting to patients with diabetes mellitus.
The content of the invention
The main object of the present invention is to provide a kind of strengthening spleen, tonifying kidney composition, with suitable for patients with diabetes mellitus.
To achieve the above object, strengthening spleen, tonifying kidney composition proposed by the present invention is made up of the raw material of following mass parts：Matrimony vine
90~110 parts of son, 110~130 parts of mulberry fruit, 90~110 parts of sealwort, 90~110 parts of dark plum processed, 90~110 parts of radix polygonati officinalis, hawthorn 90
~110 parts, 70~90 parts of oyster, 70~90 parts of spina date seed, 90~110 parts of raspberry, 90~110 parts of lily, jujube 90~110
150~180 parts of part, 90~110 parts of the root of kudzu vine, 110~130 parts of Chinese yam and corn stigma.
Preferably, the sealwort is the steaming sealwort by processing.
Preferably, the oyster is the calcined oyster shell by processing.
Preferably, the spina date seed is the Semen Ziziphi Spinosae (parched) by processing.
Preferably, the strengthening spleen, tonifying kidney composition is form of powdery particles, also include in the strengthening spleen, tonifying kidney composition dextrin,
Maltodextrin and steviol glycoside.
The present invention also provides a kind of preparation method of strengthening spleen, tonifying kidney composition, comprises the following steps：
Step 1：By 90~110 parts of the fruit of Chinese wolfberry of following mass parts, 110~130 parts of mulberry fruit, 90~110 parts of sealwort, system
90~110 parts of dark plum, 90~110 parts of radix polygonati officinalis, 90~110 parts of hawthorn, 70~90 parts of oyster, 70~90 parts of spina date seed, raspberry
90~110 parts, 90~110 parts of lily, 90~110 parts of jujube, 90~110 parts of the root of kudzu vine, 110~130 parts of Chinese yam, corn stigma 150
~180 parts and water are added in extractor and extracted, and obtain extract solution；
Step 2：Steviol glycoside is added in the extract solution that the step 1 obtains, be concentrated under reduced pressure to obtain thick paste；
Step 3：Obtained thick paste in the step 2 is dried, dry cream is made, adds maltodextrin and dextrin,
Crushed after well mixed, add soft material granulation processed, and fluidized drying, the strengthening spleen, tonifying kidney composition of form of powdery particles is made.
Preferably, the concrete operations of the step 1 are：
By 90~110 parts of the fruit of Chinese wolfberry of following mass parts, 110~130 parts of mulberry fruit, 90~110 parts of sealwort, dark plum processed 90~
110 parts, 90~110 parts of radix polygonati officinalis, 90~110 parts of hawthorn, 70~90 parts of oyster, 70~90 parts of spina date seed, raspberry 90~110
150~180 parts of part, 90~110 parts of lily, 90~110 parts of jujube, 90~110 parts of the root of kudzu vine, 110~130 parts of Chinese yam and corn stigma
Mixture is mixed and made into, mixture and the first mass parts water are added in extractor and carry out first time extraction and obtain to extract for the first time
Thing；
First extract is filtered, obtains first filtrate and the first dregs of a decoction respectively, the first dregs of a decoction are placed in extractor
In and add the second mass parts water, extracted for the second time and obtain second extract；
Second extract is filtered, obtains secondary filtrate and the secondary dregs of a decoction respectively, by first filtrate and secondary filtrate
Merge and obtain the extract solution.
Preferably, the first mass parts water is 8~10 times of amounts of the gross mass of mixture in the step 1；The step 2
In the second mass parts water for mixture 5~6 times of gross mass amounts.
Preferably, the temperature being concentrated under reduced pressure in the step 2 be 60 DEG C~70 DEG C, pressure value be -0.06MPa~-
0.08MPa；Thick paste is dried in vacuo in the step 3, vacuum drying temperature be 60 DEG C~70 DEG C, pressure value for-
0.06MPa~-0.08MPa.
Preferably, the softwood processed in the step 3 is the ethanol water that concentration is 90%~95%.
Strengthening spleen, tonifying kidney composition sugar content in the present invention is low, mouthfeel is good, suitable for patients with diabetes mellitus.By using Pueraria lobota
Root promotes the production of body fluid to quench thirst, to solve disappearing for the part of the body cavity above the diaphragm housing the heart and lungs；Radix polygonati officinalis, lily yin-nourishing increase liquid, share disappearing with Xie Zhongjiao；Chinese yam, jujube tonifying spleen lung kidney
Gas；Yijing blood that sealwort, the fruit of Chinese wolfberry, mulberry fruit, spina date seed are nourishing liver and kidney；Raspberry warms up kidney Wen Yang, and oyster is reinforced the kidney contracting spring, above conjunction
To take off the sorrow of Jiao.Corn stigma inducing diuresis for removing edema, hypotensive；Hawthorn disappears many stomach invigoratings, scattered stasis, changes turbid lipid-loweringing, to prevent in side
Flavour of a drug grow greasy property.All medicines share, resolving and invigoration therapies being applied simultaneously, Jiao of upper, middle and lower three lay equal stress on, and negative and positive of qi and blood is taken into account, and plays lung-clearing thirst-quenching, clearing stomach altogether
Stay one's hunger, the astringent or styptic treatment for spontaneous sweating effect of kidney tonifying.
Embodiment
The technical scheme in the embodiment of the present invention will be clearly and completely described below, it is clear that described implementation
Example is only the part of the embodiment of the present invention, rather than whole embodiments.It is general based on the embodiment in the present invention, this area
The every other embodiment that logical technical staff is obtained under the premise of creative work is not made, belong to what the present invention protected
Scope.
In addition, the technical scheme between each embodiment of the present invention can be combined with each other, but must be general with this area
Logical technical staff can be implemented as basis, will be understood that when the combination appearance of technical scheme is conflicting or can not realize this
The combination of technical scheme is not present, also not within the protection domain of application claims.
The present invention proposes a kind of strengthening spleen, tonifying kidney composition, and the strengthening spleen, tonifying kidney composition is made up of the raw material of following mass parts：
90~110 parts of the fruit of Chinese wolfberry, 110~130 parts of mulberry fruit, 90~110 parts of sealwort, 90~110 parts of dark plum processed, 90~110 parts of radix polygonati officinalis, mountain
90~110 parts of short, bristly hair or beard, 70~90 parts of oyster, 70~90 parts of spina date seed, 90~110 parts of raspberry, 90~110 parts of lily, jujube 90
~110 parts, 90~110 parts of the root of kudzu vine, 110~130 parts of Chinese yam, 150~180 parts of corn stigma.
Preferably, the strengthening spleen, tonifying kidney composition is made up of the raw material of following mass parts：99 parts of the fruit of Chinese wolfberry, 118.8 parts of mulberry fruit,
99 parts of sealwort, 99 parts of dark plum processed, 99 parts of radix polygonati officinalis, 99 parts of hawthorn, 79.2 parts of oyster, 79.2 parts of spina date seed, 99 parts of raspberry, lily
165 parts of 99 parts, 99 parts of jujube, 99 parts of the root of kudzu vine, 118.8 parts of Chinese yam and corn stigma.
Traditional Chinese medicine thinks, The spleen has the function to transport and transform nutrients trough, metaplasia qi and blood, is " the foundation of acquired constitution "；Kidney storing essence, main production, development and life
Grow, be " the congenital foundation ".Diabetes are referred to as quenching one's thirst in traditional Chinese medicine, to drink more, more food, diuresis, it is weak, become thin as main table
Existing, deficiency of spleen and stomach is closely related with diabetes.Promoted the production of body fluid to quench thirst in strengthening spleen, tonifying kidney composition in the present invention by using the root of kudzu vine, with
The solution part of the body cavity above the diaphragm housing the heart and lungs disappears；Radix polygonati officinalis, lily yin-nourishing increase liquid, share disappearing with Xie Zhongjiao；Chinese yam, jujube tonifying spleen lung kidney qi；Sealwort, matrimony vine
Yijing blood that son, mulberry fruit, spina date seed are nourishing liver and kidney；Raspberry warms up kidney Wen Yang, and oyster is reinforced the kidney contracting spring, is shared above to take off Jiao's
Sorrow.Corn stigma inducing diuresis for removing edema, hypotensive；Hawthorn disappears many stomach invigoratings, scattered stasis, changes turbid lipid-loweringing, and greasy property is grown to prevent square taste of traditional Chinese medicine.
All medicines share, resolving and invigoration therapies being applied simultaneously, Jiao of upper, middle and lower three lay equal stress on, and negative and positive of qi and blood is taken into account, and plays lung-clearing thirst-quenching altogether, and clearing stomach is stayed one's hunger, and kidney tonifying is astringent or styptic treatment for spontaneous sweating
Effect.
It should be noted that contribute to the blood glucose of prevention reduction diabetic using corn stigma in the present invention.Corn
Containing a variety of chemical compositions beneficial to human body in palpus, such as saponin, flavones, alkaloid, organic acid, volatile oil, trace element and more
Kind vitamin.Saponin in corn stigma is the main component for reducing diabetes patient blood sugar.Contain chromium in corn stigma, chromium is that sugar is resistance to
The part of the factor is measured, insulin function can be strengthened.The content of Flavonoid substances is 15 times of iblet in corn stigma, its
The generation of free radical can be reduced and remove free radical, there is good oxidation resistance, and corn silk water extract is removed certainly
Isoflavones is higher than by the ability of base, diabetic complication can be prevented.
Wherein, the sealwort is the steaming sealwort by processing, and the oyster is to pass through the calcined oyster shell processed, the spina date seed
For by the Semen Ziziphi Spinosae (parched) processed.
Sealwort is liliaceous plant P. kingianum (Polygonatumkingianum Coll.et Hemsl.), sealwort
(Polygonatumsibiricum Red.) or the dry rhizome of David's-harp (Polygonatumcyrtonema Hua).It is yellow
Polyoses content is higher in essence, and it is strengthening spleen, tonifying kidney composition that sealwort is made into steaming sealwort reprocessing, compared to raw sealwort, is steamed in sealwort
Polysaccharide hydrolyzable be oligosaccharide and monose, be on the one hand advantageous to the performance of drug effect, be on the other hand advantageous to diabetic suction
Receive metabolism.
Oyster (ostreagigasthunberg), its taste is salty, cold nature, enters kidney Liver Channel.Function is transquilization with heavy material, and checking exuberance of yang is mended
The moon, softening and resolving hard mass, convergence is astringent or styptic treatment for spontaneous sweating, relieving haperacidity analgesic.Oyster cures mainly insomnia of palpitating with fear, dizziness and tinnitus, scrofula subcutaneous nodule , abdominal lump of mass in abdomen, from
The illness such as band, stomachache pantothenic acid is collapsed in sweat night sweat, seminal emission.Oyster obtains calcined oyster shell after processing, and compared to oyster, calcined oyster shell is strengthened
Convergence astringent or styptic treatment for spontaneous sweating effectiveness.Diabetic generally entails gastrointestinal symptoms, and intractable diarrhea is the protrusion of part of diabetes mellitus patient
Diarrhoea occurs in symptom, the diabetes patient that there are about 20%.By adding calcined oyster shell in strengthening spleen, tonifying kidney composition in the present invention,
On the one hand the symptom of diarrhea of diabetic can be alleviated, while another aspect radix polygonati officinalis, lily, the root of kudzu vine have tonifying yin effect, also
With certain de'collement, calcined oyster shell, which restrains astringent or styptic treatment for spontaneous sweating effectiveness, can reduce radix polygonati officinalis, lily, de'collement caused by the root of kudzu vine.
In theory of traditional Chinese medical science, raw and fried sweet acid and moisten, be used for the card of liver and gall abnormal heat, the raw effect promoted the production of body fluid with clearind deficient heat partially
By force.Semen Ziziphi Spinosae (parched) acid Wen Erxiang, has the effect of being amusing concurrently, partially for liver, courage, the heart, the card that the spleen deficiency of blood is slept less.Compared to raw wild jujube
Benevolence, fry the effect enhancing that wild jujube acid convergence stops abnormal sweating；In addition, the Semen Ziziphi Spinosae (parched) obtained by processing is more fragrant, perfume (or spice) can be amusing,
On the one hand absorption of the stomach and intestine to medicine can be promoted, is on the other hand beneficial to the mouthfeel for increasing strengthening spleen, tonifying kidney composition.
Further, the strengthening spleen, tonifying kidney composition is form of powdery particles, also includes paste in the strengthening spleen, tonifying kidney composition
Essence, maltodextrin and steviol glycoside.The calorific value of steviol glycoside is only the 1/300 of sucrose, is not absorbed, not produced after taking in human body
Heat, it is free of a burden after diabetes patient so as to improve the mouthfeel of the strengthening spleen, tonifying kidney composition.By by the strengthening spleen, tonifying kidney
Form of powdery particles is made in composition, is watered after brewing i.e. edible, easy to carry.
Strengthening spleen, tonifying kidney composition proposed by the present invention and preparation method thereof is carried out specifically below by way of specific embodiment
It is bright：
Embodiment one
A kind of strengthening spleen, tonifying kidney composition, the raw material of following mass parts are made：100 parts of the fruit of Chinese wolfberry, 120 parts of mulberry fruit, sealwort 100
Part, 100 parts of dark plum processed, 100 parts of radix polygonati officinalis, 100 parts of hawthorn, 80 parts of oyster, 80 parts of spina date seed, 100 parts of raspberry, 100 parts of lily,
165 parts of 100 parts of jujube, 100 parts of the root of kudzu vine, 120 parts of Chinese yam and corn stigma.
The preparation method of the strengthening spleen, tonifying kidney composition comprises the following steps：
Step S11, by 100 parts of the fruit of Chinese wolfberry of following mass parts, 120 parts of mulberry fruit, 100 parts of sealwort, 100 parts of dark plum processed, jade
100 parts of bamboo, 100 parts of hawthorn, 80 parts of oyster, 80 parts of spina date seed, 100 parts of raspberry, 100 parts of lily, 100 parts of jujube, the root of kudzu vine 100
Part, 120 parts of Chinese yam, 165 parts of corn stigma and water are added in extractor and extracted, and obtain extract solution；
Step S111, by 100 parts of the fruit of Chinese wolfberry of following mass parts, 120 parts of mulberry fruit, 100 parts of sealwort, 100 parts of dark plum processed, jade
100 parts of bamboo, 100 parts of hawthorn, 80 parts of oyster, 80 parts of spina date seed, 100 parts of raspberry, 100 parts of lily, 100 parts of jujube, the root of kudzu vine 100
Part, 165 parts of 120 parts of Chinese yam and corn stigma be mixed and made into mixture, mixture and the first mass parts water are added in extractor
Row extracts for the first time and obtains first extract；
Specifically, above-mentioned each composition is weighed respectively with mass parts：100 parts of the fruit of Chinese wolfberry, 120 parts of mulberry fruit, 100 parts of sealwort, system
100 parts of dark plum, 100 parts of radix polygonati officinalis, 100 parts of hawthorn, 80 parts of oyster, 80 parts of spina date seed, 100 parts of raspberry, 100 parts of lily, jujube
165 parts of 100 parts, 100 parts of the root of kudzu vine, 120 parts of Chinese yam and corn stigma, said mixture is placed in extractor, adds above-mentioned mixing
The pure water of 9 times of amounts of thing gross mass, it is 100 DEG C to set Extracting temperature, Dynamic Extraction 120 minutes, obtains first extract.
Step S112, is filtered to first extract, obtains first filtrate and the first dregs of a decoction respectively, and the first dregs of a decoction are put
In extractor and the second mass parts water is added, is extracted for the second time and obtains second extract；
Specifically, the mesh filtered through gauze of first extract 200 that will be obtained in step S111, obtain respectively first filtrate and just
The secondary dregs of a decoction, the first dregs of a decoction are placed in extractor and add the water of 5.5 times of amounts of said mixture gross mass, and setting Extracting temperature is
100 DEG C, Dynamic Extraction 60 minutes, extracted for the second time and obtain second extract
Step S113, the step S112 second extracts obtained are filtered, obtain secondary filtrate and secondary medicine respectively
Slag, first filtrate is merged with secondary filtrate and obtains the extract solution.
Specifically, the mesh filtered through gauze of second extract 200 obtained to step S112, secondary filtrate and secondary is obtained respectively
The dregs of a decoction.
Step S12, steviol glycoside is added in the extract solution that the step S11 is obtained, be concentrated under reduced pressure to obtain thick paste；
Specifically, in the extract solution obtained in the step S113 add 7 parts of steviol glycoside, pressure value for-
0.07MPa, temperature are concentrated under reduced pressure under the conditions of being 65 DEG C, obtain the thick paste that relative density is 1.25-1.3；
Step S13, obtained thick paste in the step S12 is dried, dry cream is made, add maltodextrin and paste
Essence, crushed after well mixed, add soft material granulation processed, and the strengthening spleen, tonifying kidney composition of the form of powdery particles of fluidized drying.
Specifically, thick paste is dried in vacuo under the conditions of pressure value is -0.07MPa, temperature is 65 DEG C, got dry extract,
600 parts of 60 parts of maltodextrin and dextrin are added, is crushed after well mixed, the ethanol water that concentration is 93% is added and pelletizes, and
Fluidized drying to water content is less than 5%, 12 mesh sieve whole grains, obtains 1000 parts of the strengthening spleen, tonifying kidney composition grain of form of powdery particles.
It is understood that can also use spray drying to thick paste, those skilled in the art can enter according to actual conditions
Row selection.
It is softwood processed to add the ethanol water that concentration is 93%, and the thick paste for making to make in step S2 has certain viscosity and wet
Degree, so that form of powdery particles is suitably made.
Embodiment two
A kind of strengthening spleen, tonifying kidney composition, the raw material of following mass parts are made：90 parts of the fruit of Chinese wolfberry, 110 parts of mulberry fruit, sealwort 90
Part, 90 parts of dark plum processed, 90 parts of radix polygonati officinalis, 90 parts of hawthorn, 70 parts of oyster, 70 parts of spina date seed, 90 parts of raspberry, 90 parts of lily, jujube
150 parts of 90 parts, 90 parts of the root of kudzu vine, 170 parts of Chinese yam and corn stigma.
The preparation method of the strengthening spleen, tonifying kidney composition comprises the following steps：
Step S21, by 90 parts of the fruit of Chinese wolfberry of following mass parts, 110 parts of mulberry fruit, 90 parts of sealwort, 90 parts of dark plum processed, radix polygonati officinalis 90
Part, 90 parts of hawthorn, 70 parts of oyster, 70 parts of spina date seed, 90 parts of raspberry, 90 parts of lily, 90 parts of jujube, 90 parts of the root of kudzu vine, Chinese yam 170
Part, 150 parts of corn stigma and water are added in extractor and extracted, and obtain extract solution；
Step S211, by 90 parts of the fruit of Chinese wolfberry of following mass parts, 110 parts of mulberry fruit, 90 parts of sealwort, 90 parts of dark plum processed, radix polygonati officinalis
90 parts, 90 parts of hawthorn, 70 parts of oyster, 70 parts of spina date seed, 90 parts of raspberry, 90 parts of lily, 90 parts of jujube, 90 parts of the root of kudzu vine, Chinese yam
170 parts and 150 parts of corn stigma are mixed and made into mixture, and mixture and the first mass parts water are added in extractor and carried out for the first time
Extract and obtain first extract；
Specifically, above-mentioned each composition is weighed respectively with mass parts：90 parts of the fruit of Chinese wolfberry, 110 parts of mulberry fruit, 90 parts of sealwort, system crow
90 parts of plum, 90 parts of radix polygonati officinalis, 90 parts of hawthorn, 70 parts of oyster, 70 parts of spina date seed, 90 parts of raspberry, 90 parts of lily, 90 parts of jujube, Pueraria lobota
90 parts of root, 170 parts of Chinese yam, 150 parts of corn stigma, said mixture is placed in extractor, adds 8 times of said mixture gross mass
The water of amount, it is 90 DEG C to set Extracting temperature, Dynamic Extraction 140 minutes, obtains first extract.
Step S212, is filtered to first extract, obtains first filtrate and the first dregs of a decoction respectively, and the first dregs of a decoction are put
In extractor and the second mass parts water is added, is extracted for the second time and obtains second extract；
Specifically, the mesh filtered through gauze of first extract 200 that will be obtained in step S211, obtain respectively first filtrate and just
The secondary dregs of a decoction, the first dregs of a decoction are placed in extractor and add the water of 5 times of amounts of said mixture gross mass, it is 90 to set Extracting temperature
DEG C, Dynamic Extraction 70 minutes, extracted for the second time and obtain second extract
Step S213, the step S212 second extracts obtained are filtered, obtain secondary filtrate and the dregs of a decoction respectively, will
First filtrate merges with secondary filtrate obtains the extract solution.
Specifically, the mesh filtered through gauze of second extract 200 obtained to step S212, secondary filtrate and secondary is obtained respectively
The dregs of a decoction.
Step S22, steviol glycoside is added in the extract solution that the step S21 is obtained, be concentrated under reduced pressure to obtain thick paste；
Specifically, in the extract solution obtained in the step S213 add 6 parts of steviol glycoside, pressure value for-
0.06MPa, temperature are concentrated under reduced pressure under the conditions of being 60 DEG C, obtain the thick paste that relative density is 1.20-1.25；
Step S23, obtained thick paste in the step S22 is dried, dry cream is made, add maltodextrin and paste
Essence, crushed after well mixed, add soft material granulation processed, and the strengthening spleen, tonifying kidney composition of the form of powdery particles of fluidized drying.
Specifically, thick paste is dried in vacuo under the conditions of pressure value is -0.06MPa, temperature is 60 DEG C, got dry extract,
580 parts of 55 parts of maltodextrin and dextrin are added, is crushed after well mixed, concentration is added and is pelletized for 90% ethanol water, and boil
Rise to dry to water content and be less than 5%, 12 mesh sieve whole grains, obtain 1000 parts of the strengthening spleen, tonifying kidney composition grain of form of powdery particles.
Embodiment three
A kind of strengthening spleen, tonifying kidney composition, the raw material of following mass parts are made：110 parts of the fruit of Chinese wolfberry, 130 parts of mulberry fruit, sealwort 110
Part, 110 parts of dark plum processed, 110 parts of radix polygonati officinalis, 110 parts of hawthorn, 90 parts of oyster, 90 parts of spina date seed, 110 parts of raspberry, 110 parts of lily,
180 parts of 110 parts of jujube, 110 parts of the root of kudzu vine, 130 parts of Chinese yam and corn stigma.
The preparation method of the strengthening spleen, tonifying kidney composition comprises the following steps：
Step S31, by 110 parts of the fruit of Chinese wolfberry of following mass parts, 130 parts of mulberry fruit, 110 parts of sealwort, 110 parts of dark plum processed, jade
110 parts of bamboo, 110 parts of hawthorn, 90 parts of oyster, 90 parts of spina date seed, 110 parts of raspberry, 110 parts of lily, 110 parts of jujube, the root of kudzu vine 110
Part, 130 parts of Chinese yam, 180 parts of corn stigma and water are added in extractor and extracted, and obtain extract solution；
Step S311, by 110 parts of the fruit of Chinese wolfberry of following mass parts, 130 parts of mulberry fruit, 110 parts of sealwort, 110 parts of dark plum processed, jade
110 parts of bamboo, 110 parts of hawthorn, 90 parts of oyster, 90 parts of spina date seed, 110 parts of raspberry, 110 parts of lily, 110 parts of jujube, the root of kudzu vine 110
Part, 180 parts of 130 parts of Chinese yam and corn stigma be mixed and made into mixture, mixture and the first mass parts water are added in extractor
Row extracts for the first time and obtains first extract；
Specifically, above-mentioned each composition is weighed respectively with mass parts：110 parts of the fruit of Chinese wolfberry, 130 parts of mulberry fruit, 110 parts of sealwort, system
110 parts of dark plum, 110 parts of radix polygonati officinalis, 110 parts of hawthorn, 90 parts of oyster, 90 parts of spina date seed, 110 parts of raspberry, 110 parts of lily, jujube
110 parts, 110 parts of the root of kudzu vine, 130 parts of Chinese yam, 180 parts of corn stigma, said mixture is placed in extractor, add said mixture
The water of 10 times of amounts of gross mass, it is 100 DEG C to set Extracting temperature, Dynamic Extraction 110 minutes, obtains first extract.
Step S312, is filtered to first extract, obtains first filtrate and the first dregs of a decoction respectively, and the first dregs of a decoction are put
In extractor and the second mass parts water is added, is extracted for the second time and obtains second extract；
Specifically, the mesh gauze of first extract 200 obtained in step S311 is filtered, obtains first filtrate respectively
With the first dregs of a decoction, the first dregs of a decoction are placed in extractor and add the water of 6 times of amounts of said mixture gross mass, Extracting temperature is set
For 100 DEG C, Dynamic Extraction 50 minutes, extracted for the second time and obtain second extract
Step S313, the step S312 second extracts obtained are filtered, obtain secondary filtrate and secondary medicine respectively
Slag, first filtrate is merged with secondary filtrate and obtains the extract solution.
Specifically, the mesh filtered through gauze of second extract 200 obtained to step S312, secondary filtrate and secondary is obtained respectively
The dregs of a decoction.
Step S32, steviol glycoside is added in the extract solution that the step S31 is obtained, be concentrated under reduced pressure to obtain thick paste；
Specifically, in the extract solution obtained in the step S313 add 8 parts of steviol glycoside, pressure value for-
0.08MPa, temperature are concentrated under reduced pressure under the conditions of being 70 DEG C, obtain the thick paste that relative density is 1.25-1.3；
Step S33, obtained thick paste in the step S32 is dried, dry cream is made, add maltodextrin and paste
Essence, crushed after well mixed, add soft material granulation processed, and the strengthening spleen, tonifying kidney composition of the form of powdery particles of fluidized drying.
Specifically, thick paste is dried in vacuo under the conditions of pressure value is -0.08MPa, temperature is 70 DEG C, got dry extract,
630 parts of 65 parts of maltodextrin and dextrin are added, is crushed after well mixed, concentration is added and is pelletized for 95% ethanol water, and boil
Rise to dry to water content and be less than 5%, 12 mesh sieve whole grains, obtain 1000 parts of the strengthening spleen, tonifying kidney composition grain of form of powdery particles.
There is certain prevention, intervention effect to diabetes to illustrate strengthening spleen, tonifying kidney composition of the present invention, with by above-mentioned
Strengthening spleen, tonifying kidney composition is tested made from method in embodiment 1~3, to prove that it has certain prevention, intervention effect,
But it can not form any restrictions to the scope of the present invention.
It is each 80 of 50~60 years old men and women for meeting type II diabetes to select the age, is divided into 4 groups, each group includes 20 men
Property, 20 women.1st group totally 40, man 20, female 20, the age be (55.18 ± 2.37) year, the course of disease for (18.79 ±
28.39) individual month, strengthening spleen, tonifying kidney composition made from the method in embodiment 1 is eaten；2nd group totally 40, man 20, female 20,
Age be (53.17 ± 2.21) year, the course of disease is (20.19 ± 28.11) individual month, strengthening spleen, tonifying kidney made from the method in embodiment 2
Composition；3rd group totally 40, man 20, female 20, the age be (54.56 ± 3.56) year, the course of disease be (19.33 ± 27.16) it is individual
Month, eat strengthening spleen, tonifying kidney composition made from the method in embodiment 3；4th group totally 40, man 20, female 20, the age is
In (53.89 ± 2.65) year, the course of disease is (20.35 ± 28.21) individual month edible placebo.During experiment, everyone is every for experimental group
Day respectively takes the strengthening spleen, tonifying kidney composition of the 10g present invention for 1 hour before meals sooner or later.Through statistics, two groups in sex, age, course of disease etc.
There was no significant difference for aspect (P ＞ 0.05), has comparativity.Exclusion standard：(1) IDDM patient；(2) with severe cardiac,
Liver and kidney function is not complete and acute infection patient；(3) nursing period, pregnancy women.
Table 1 is referred to, table 1 is to eat the effect research table after strengthening spleen, tonifying kidney composition of the present invention.Wherein, with thirsty more
Drink, polyorexia, dysphoria in chestpalms-soles, lassitude hypodynamia are that symptom is scored, and symptom efficacy evaluation is classified by level Four point system：0 (nothing
Symptom), 1 (can sensory symptoms presence when must be through reminding), 2 (having symptom sometimes), 3 (symptom is obvious), and carry out symptom score
And integration.≤ 4 points of scoring is effective, and 4 ＜ score≤8 points, is effective；It is invalid that scoring, which is more than 8 points,.
Table 1 eats the effect research table after strengthening spleen, tonifying kidney composition of the present invention
| Group | Number of cases | It is effective | Effectively | It is invalid | Total effective rate |
| Embodiment 1 | 40 | 17 | 21 | 2 | 95.0% |
| Embodiment 2 | 40 | 17 | 20 | 3 | 92.5% |
| Embodiment 3 | 40 | 14 | 25 | 1 | 97.5% |
| Control group | 40 | 8 | 6 | 26 | 35.0% |
Table 2 is referred to, table 2 is to eat the blood sugar test table after strengthening spleen, tonifying kidney composition of the present invention.Experimental subjects is detected
FPG (fasting blood-glucose), P2hPG (postprandial 2 hours blood glucose).
Table 2 eats the blood sugar test table after strengthening spleen, tonifying kidney composition of the present invention
The strengthening spleen, tonifying kidney composition that can be observed to prepare in embodiment 1~3 by table 2 eats invigorating the spleen and mended compared with control group
Patient FPG, P2hPG value of kidney composition reduce (P ＜ 0.05).
The preferred embodiments of the present invention are the foregoing is only, are not intended to limit the scope of the invention, it is every at this
Under the inventive concept of invention, the equivalent structure transformation made using description of the invention, or directly/to be used in other indirectly related
Technical field be included in the present invention scope of patent protection in.
Claims (10)
1. a kind of strengthening spleen, tonifying kidney composition, it is characterised in that it is made up of the raw material of following mass parts：90~110 parts of the fruit of Chinese wolfberry,
110~130 parts of mulberry fruit, 90~110 parts of sealwort, 90~110 parts of dark plum processed, 90~110 parts of radix polygonati officinalis, 90~110 parts of hawthorn, oyster
70~90 parts, 70~90 parts of spina date seed, 90~110 parts of raspberry, 90~110 parts of lily, 90~110 parts of jujube, the root of kudzu vine 90~
150~180 parts of 110 parts, 110~130 parts of Chinese yam and corn stigma.
2. strengthening spleen, tonifying kidney composition as claimed in claim 1, it is characterised in that the sealwort is the steaming sealwort by processing.
3. strengthening spleen, tonifying kidney composition as claimed in claim 1, it is characterised in that the oyster is the calcined oyster shell by processing.
4. strengthening spleen, tonifying kidney composition as claimed in claim 1, it is characterised in that the spina date seed is the stir-fry wild jujube by processing
Benevolence.
5. the strengthening spleen, tonifying kidney composition as any one of Claims 1-4, it is characterised in that the strengthening spleen, tonifying kidney combination
Thing is form of powdery particles, and dextrin, maltodextrin and steviol glycoside are also included in the strengthening spleen, tonifying kidney composition.
6. a kind of preparation method of strengthening spleen, tonifying kidney composition, it is characterised in that comprise the following steps：
Step 1：By 90~110 parts of the fruit of Chinese wolfberry of following mass parts, 110~130 parts of mulberry fruit, 90~110 parts of sealwort, dark plum processed
90~110 parts, 90~110 parts of radix polygonati officinalis, 90~110 parts of hawthorn, 70~90 parts of oyster, 70~90 parts of spina date seed, raspberry 90~
110 parts, 90~110 parts of lily, 90~110 parts of jujube, 90~110 parts of the root of kudzu vine, 110~130 parts of Chinese yam, corn stigma 150~180
Part and water, which are added in extractor, to be extracted, and obtains extract solution；
Step 2：Steviol glycoside is added in the extract solution that the step 1 obtains, be concentrated under reduced pressure to obtain thick paste；
Step 3：Obtained thick paste in the step 2 is dried, dry cream is made, adds maltodextrin and dextrin, mixing
Crushed after uniformly, add soft material granulation processed, and fluidized drying, the strengthening spleen, tonifying kidney composition of form of powdery particles is made.
7. the preparation method of strengthening spleen, tonifying kidney composition as claimed in claim 6, it is characterised in that the specific behaviour of the step 1
As：
By 90~110 parts of the fruit of Chinese wolfberry of following mass parts, 110~130 parts of mulberry fruit, 90~110 parts of sealwort, dark plum processed 90~110
Part, 90~110 parts of radix polygonati officinalis, 90~110 parts of hawthorn, 70~90 parts of oyster, 70~90 parts of spina date seed, 90~110 parts of raspberry, hundred
150~180 parts of 90~110 parts of conjunction, 90~110 parts of jujube, 90~110 parts of the root of kudzu vine, 110~130 parts of Chinese yam and corn stigma mixing
Mixture is made, mixture and the first mass parts water are added in extractor and carries out first time extraction and obtains first extract；
First extract is filtered, obtains first filtrate and the first dregs of a decoction respectively, the first dregs of a decoction are placed in extractor simultaneously
The second mass parts water is added, is extracted for the second time and obtains second extract；
Second extract is filtered, obtains secondary filtrate and the secondary dregs of a decoction respectively, first filtrate is merged with secondary filtrate
Obtain the extract solution.
8. the preparation method of strengthening spleen, tonifying kidney composition as claimed in claim 7, it is characterised in that the first matter in the step 1
Measure 8~10 times amounts of part water for the gross mass of mixture；The second mass parts water is the 5 of the gross mass of mixture in the step 2
~6 times of amounts.
9. the preparation method of strengthening spleen, tonifying kidney composition as claimed in claim 6, it is characterised in that depressurized in the step 2 dense
The temperature of contracting is 60 DEG C~70 DEG C, and pressure value is -0.06MPa~-0.08MPa；Vacuum is carried out in the step 3 to thick paste to do
Dry, vacuum drying temperature is 60 DEG C~70 DEG C, and pressure value is -0.06MPa~-0.08MPa.
10. the preparation method of the strengthening spleen, tonifying kidney composition as any one of claim 6 to 9, it is characterised in that the step
Softwood processed in rapid three is the ethanol water that concentration is 90%~95%.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109464598A (en) * | 2018-12-28 | 2019-03-15 | 贵州爱多康生物科技有限公司 | A kind of composition and preparation method thereof containing Acer truncatum leaves for health drink |
| CN113785981A (en) * | 2021-10-14 | 2021-12-14 | 潘学群 | Health-preserving medicinal and edible composition and preparation method thereof |
| CN117678746A (en) * | 2024-01-13 | 2024-03-12 | 山西东方傅山中医药研究院 | Food with spleen strengthening and dampness eliminating functions and preparation method thereof |
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| CN103859378A (en) * | 2012-12-10 | 2014-06-18 | 天津红日药业股份有限公司 | Formula and preparation method of life cultivation and health preservation food helpful for reducing blood sugar |
| CN104547547A (en) * | 2014-12-30 | 2015-04-29 | 兰州古驰生物科技有限公司 | Traditional Chinese medicine preparation used for comprehensively conditioning health of five internal organs |
| CN106728868A (en) * | 2016-12-28 | 2017-05-31 | 陕西红顶名医堂药业有限公司 | Chinese medicine composition and preparation method thereof for treating diabetes |
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2017
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103859378A (en) * | 2012-12-10 | 2014-06-18 | 天津红日药业股份有限公司 | Formula and preparation method of life cultivation and health preservation food helpful for reducing blood sugar |
| CN104547547A (en) * | 2014-12-30 | 2015-04-29 | 兰州古驰生物科技有限公司 | Traditional Chinese medicine preparation used for comprehensively conditioning health of five internal organs |
| CN106728868A (en) * | 2016-12-28 | 2017-05-31 | 陕西红顶名医堂药业有限公司 | Chinese medicine composition and preparation method thereof for treating diabetes |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109464598A (en) * | 2018-12-28 | 2019-03-15 | 贵州爱多康生物科技有限公司 | A kind of composition and preparation method thereof containing Acer truncatum leaves for health drink |
| CN113785981A (en) * | 2021-10-14 | 2021-12-14 | 潘学群 | Health-preserving medicinal and edible composition and preparation method thereof |
| CN117678746A (en) * | 2024-01-13 | 2024-03-12 | 山西东方傅山中医药研究院 | Food with spleen strengthening and dampness eliminating functions and preparation method thereof |
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Application publication date: 20171229 |