CN107510633A - A kind of ocular cell assigns anti-ageing Essence living and preparation method thereof - Google Patents
A kind of ocular cell assigns anti-ageing Essence living and preparation method thereof Download PDFInfo
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- CN107510633A CN107510633A CN201710924067.8A CN201710924067A CN107510633A CN 107510633 A CN107510633 A CN 107510633A CN 201710924067 A CN201710924067 A CN 201710924067A CN 107510633 A CN107510633 A CN 107510633A
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract
The present invention proposes a kind of ocular cell and assigns anti-ageing Essence living, using freeze-dried powder and elite solvent formula formulation.Freeze-dried powder includes：Mannitol, trehalose, carnosine, Sodium Hyaluronate, oligopeptides 1, oligopeptides 3, oligopeptides 5 and pure water；Elite solvent includes：Glycerine, brewer's yeast fungus extract, peppery mint extract, upland cotton extract, Alfalfa P.E, Wild soybean albumen, hydrolysis Candida extract, preservative, through acid amides 3, EDTA 2Na and pure water.The invention also provides a kind of ocular cell assigns the preparation method of anti-ageing Essence living.
Description
Technical field
The present invention relates to eye care products technical field, be specifically related to a kind of ocular cell assign anti-ageing Essence living and
Its preparation method.
Background technology
Eye anti-aging nursing be each mature women's common concern demand, the master of even more modern skin protection cosmetics development
Offense to.The product of in the market eye anti-aging is a lot, e.g., lift, compact, be crease-resistant, pouch of dispelling, livid ring around eye of dispelling, whitening etc., machine
In reason mostly according to the moisturizing in cosmeceutical meaning, moisturizing, releive, repair, from physiology, dermatology, Biological Mechanism
On, anti-oxidant, anti-cell damage, cell-activating, barrier maintenance is become more important, and the product of this respect, and existing technology is either selected
More defect all be present in material, formula design, or compound method, production technology.
The content of the invention
The present invention proposes a kind of ocular cell and assigns anti-ageing Essence living, using freeze-dried powder and elite solvent formula formulation.
The ocular cell proposed by the present invention is assigned in anti-ageing Essence living, and the freeze-dried powder includes：Mannitol, marine alga
Sugar, carnosine, Sodium Hyaluronate, oligopeptides -1, oligopeptides -3, oligopeptides -5 and pure water；The elite solvent includes：Glycerine, brewer's yeast
Fungus extract, peppery mint extract, upland cotton extract, Alfalfa P.E, Wild soybean albumen, hydrolysis Candida extraction
Thing, preservative, through acid amides 3, EDTA-2Na and pure water.
The ocular cell proposed by the present invention is assigned in anti-ageing Essence living, the preservative be decoyl hydroximic acid, oneself two
Alcohol, the one of which of 1,3- propane diols or two or more any combination.
The ocular cell proposed by the present invention is assigned in anti-ageing Essence living, is formed with the composition of following mass percent：
Mannitol 1.5-3.5；Trehalose 0.5-1.5；Carnosine 0.05-0.2；Sodium Hyaluronate 0.05-0.15；Oligopeptides -10.04-
0.08；Oligopeptides -30.008-0.015；Oligopeptides -50.008-0.015；Glycerine 2.0-5.0；Brewer's yeast fungus extract 2.0-5.0；
Peppery mint extract 2.0-5.0；Upland cotton extract 2.0-4.0；Alfalfa P.E 2.0-4.0；Wild soybean albumen 1.0-
4.0；Hydrolyze Candida extract 0.5-3.0；Preservative 0.5-1.0；Cer NP 0.3-0.5；EDTA-2Na0.05-
0.1；Pure water surplus.
The invention also provides a kind of ocular cell tax anti-ageing elite liquid and preparation method thereof living, prepare freeze-dried powder and elite is molten
Matchmaker, then be made after uniformly mixing the freeze-dried powder and the elite solvent.
The ocular cell proposed by the present invention is assigned in anti-ageing elite liquid and preparation method thereof living, and prepared by freeze-dried powder include following step
Suddenly：
Weighed by formula and singly weigh each component to respective container.
At room temperature, pure water is added in vacuum emulsifying pot, adds Sodium Hyaluronate, be heated to temperature while stirring
60 DEG C, homogeneous 3-4 minutes are beaten, stirring and dissolving is uniform, sequentially adds mannitol, trehalose, stirring to being uniformly dissolved；
Less than 10 DEG C are cooled to, carnosine, oligopeptides -1, oligopeptides -3, oligopeptides -5 is sequentially added, is uniformly mixed；
Filtering and discharging after the assay was approved, in filling to lyophilized bottle (cillin bottle or Butting bottle), filling amount 3ml；It is put into vacuum
In freeze drier, freeze-drying curve is set, is lyophilized into freeze-dried powder.
The ocular cell proposed by the present invention is assigned in anti-ageing elite liquid and preparation method thereof living, and elite solvent is prepared including as follows
Step：
Weighed by formula and singly weigh each component to respective container；
At room temperature, pure water is added in vacuum emulsifying pot, under stirring, sequentially add glycerine, EDTA-2Na,
Brewer's yeast fungus extract, peppery mint extract, upland cotton extract, Alfalfa P.E, Wild soybean albumen, alfalfa extraction
Thing, hydrolysis Candida extract, Cer NP, a material is often added, interval stirring 2-3 minutes, after adding, is stirred for 20
Minute is completely dissolved uniformly；Preservative is added, continues stirring 10 minutes, is well mixed；
Filtering and discharging after the assay was approved, stand and sample afterwards and do the inspection of semifinished product, it is filling after qualified to be into Packaging Bottle
Can.
The ocular cell proposed by the present invention is assigned in anti-ageing elite liquid and preparation method thereof living, and inspection includes：Sampling observation is outer
Sight, color and luster, smell, viscosity, pH value, meet quality control standard QB/T2660 requirements.
Embodiment
Anti-ageing Essence living and preparation method thereof is assigned to ocular cell proposed by the present invention below in conjunction with schematic diagram to carry out
More detailed description, which show the preferred embodiments of the present invention, it should be appreciated that those skilled in the art can change herein
The present invention of description, and still realize the advantageous effects of the present invention.Therefore, description below is appreciated that for this area skill
Art personnel's is widely known, and is not intended as limitation of the present invention.
The present invention proposes a kind of ocular cell and assigns anti-ageing Essence living, using freeze-dried powder and elite solvent formula formulation.
The ocular cell proposed by the present invention is assigned in anti-ageing Essence living, and the freeze-dried powder includes：Mannitol, marine alga
Sugar, carnosine, Sodium Hyaluronate, oligopeptides -1, oligopeptides -3, oligopeptides -5 and pure water；The elite solvent includes：Glycerine, brewer's yeast
Fungus extract, peppery mint extract, upland cotton extract, Alfalfa P.E, Wild soybean albumen, hydrolysis Candida extraction
Thing, preservative, through acid amides 3, EDTA-2Na and pure water.
The ocular cell proposed by the present invention is assigned in anti-ageing Essence living, the preservative be decoyl hydroximic acid, oneself two
Alcohol, the one of which of 1,3- propane diols or two or more any combination.
The ocular cell proposed by the present invention is assigned in anti-ageing Essence living, is formed with the composition of following mass percent：
Mannitol 1.5-3.5；Trehalose 0.5-1.5；Carnosine 0.05-0.2；Sodium Hyaluronate 0.05-0.15；Oligopeptides -10.04-
0.08；Oligopeptides -30.008-0.015；Oligopeptides -50.008-0.015；Glycerine 2.0-5.0；Brewer's yeast fungus extract 2.0-5.0；
Peppery mint extract 2.0-5.0；Upland cotton extract 2.0-4.0；Alfalfa P.E 2.0-4.0；Wild soybean albumen 1.0-
4.0；Hydrolyze Candida extract 0.5-3.0；Preservative 0.5-1.0；Cer NP 0.3-0.5；EDTA-2Na0.05-
0.1；Pure water surplus.
Raw materials are commercially available specialty products in inventive formulation.
Mannitol in the present invention, also known as mannitol, are made using starch sugar or sucrose as raw material, are a kind of conventional moisturizings
Agent.It is used as freeze-dried excipient in the present invention.
Trehalose in the present invention, it is a kind of disaccharides for being present in mushroom, yeast powder, marine alga and shrimp.With very strong
Moisture-retaining capacity, drying can be effectively resisted, repair damaged skin.It is used as freeze-dried excipient in the present invention.
Carnosine in the present invention, i.e. β-alanyl-L-Histidine, it is that a kind of can be played in two different levels resists
The active matter of aging effect：Hinder radical reaction and glycosylation (protection effect)；Prevent products of oxidative stress and glycosyl
Change end (AGE) product and produce (reparation effect).
Sodium Hyaluronate in the present invention, sodium hyaluronate sodium or uronic acid sodium are called, are fermented and be made by Lactococcus.It is a kind of
Widely used NMF.It is used as lyophilized figuration auxiliary agent in the present invention.
Oligopeptides -1 in the present invention, abbreviation EGF, i.e. EGF, it is made by Escherichia coli fermentation method.It is a kind of water
The nonglycosylated small protein of dissolubility, containing 53 amino acid residues, skin repair is widely used in, has and promote new skin thin
The generation of born of the same parents reduces and prevents microgroove and the generation of wrinkle, nourishes rough skin make it more fine and smooth, glossy, reappears the work(such as youth
Effect.
Oligopeptides -3 in the present invention, abbreviation bFGF, i.e. basic fibroblast growth factor, by Escherichia coli fermentation legal system
, it is a kind of cationic polypeptide for containing 155 amino acid.Repaired with efficient, smooth away wrinkles, calm down scar, whitening is ruddy
Effect.
Oligopeptides -5 in the present invention, abbreviation KGF-2, i.e. keratinocyte growth factor, it is made by Escherichia coli fermentation method.Contain
169 amino acid.With keratinocyte proliferation, renewal can be promoted, the regeneration of wound circumference epithelial cell is stimulated, breaks up and moves
Move, therefore the scar that can effectively heal, repair damage.
Glycerine in the present invention, it is a kind of conventional NMF in natural oil saponification source.
Saccharomyces cerevisiae (SACCHAROMYCESCEREVIS) extract in the present invention, by being extracted in brewer's yeast
A kind of polysaccharide active components, and it is rich in nicotinic acid.With capillary system is strengthened, vascular endothelial growth factor is improved
VEGF is synthesized, and promotes vascular tissue's vigor, is improved microcirculation function, can effectively be reduced pouch (edema), Vitamin K.Keep
Young face, change youth brilliance.
Peppery peppermint (MENTHAPIPERITA) extract in the present invention, rich in dried peppermint leaf flavanones.Stimulated with alleviating
Property material trigger erythema, the sensitive malaise symptoms such as scorching hot, shouting pain, strengthen cutaneous immunisation function, reduce inflammatory phenomena.
Upland cotton (GOSSYPIUMHIRSUTUM) extract in the present invention, it is that a kind of plant peptide by cottonseed extraction is (pure
Change cottonseed peptide).Can activating skin cell DNA self-regeneration system, damage caused by reducing sunshine ultraviolet (UV), repair
DNA, prevent light aging.
Alfalfa (MEDICAGOSATIVA) extract in the present invention, extracted from alfalfa, rich in galactomannans,
There is the effectiveness similar to vitamin A to epidermis and dermal cell：Keratinocyte differentiation and collagen synthesis are excited, is promoted thin
Born of the same parents' metabolism, shine new skin, bright color.
Wild soybean (GLYCINESOJA) albumen in the present invention, extracted from soybean epidermis, it is more rich in glycoprotein and structure
Sugar.With skin corium collagen, the glutinous complex functionality such as polysaccharide and fibrillin is improved, its three-dimensional network can be strengthened, improve skin
The degree of packing and elasticity of skin, substantially reduce crow's feet and muffle fold line.
Hydrolysis Candida (CANDIDASAITOANA) extract in the present invention, is extracted from Antagonistic yeast
One kind purifying active component a- glucans.With skin autophagy system (i.e. cell toxin expelling system) is stimulated, remove intracellular
The meeting of accumulation poisons the variation composition of cell, so as to reach protection cell, excites its vigor, reduces aging, crease-resistant, highlight skin
Color.
Preservative in the present invention is decoyl hydroximic acid (and) hexylene glycol (and) 1,3-PD, be it is a kind of it is extremely gentle,
The compound preservative of safety, anti-corrosion stabilization is played to system.
Cer NP in the present invention, extracted by fermentations such as wheat, rice.Cer NP is in corneocyte interstitial
Most important component, extremely important effect is played to skin moisturizing barrier.It can help to supplement the ceramide that skin lacks, weight
Structure skin moisturizing ability, skin is set to become soft, it is smooth, recover elasticity.
EDTA-2Na in the present invention, is conventional chelating agent, and stabilization is played to system.
Pure water in the present invention, it is that running water passes through the deionized water that two-pass reverse osmosis (RO) and electric desalination (EDI) obtain.
Using preceding also needing to through 90 DEG C, 30 minutes high temperature sterilizations.
With reference to embodiments 1,2,3, it is specifically described the formula that ocular cell of the present invention assigns anti-ageing Essence living
Embodiment 1
A kind of ocular cell assigns anti-ageing Essence living, using freeze-dried powder and elite solvent formula formulation, by mass percent
Composition composition：
Elite solvent：
Preparation method comprises the following steps that：
Freeze-dried powder：
Weighed by formula and singly weigh each component to respective container.
At room temperature, pure water is added in vacuum emulsifying pot, adds Sodium Hyaluronate, be heated to temperature while stirring
60 DEG C, homogeneous 3-4 minutes are beaten, stirring and dissolving is uniform, sequentially adds mannitol, trehalose, stirring to being uniformly dissolved.
Less than 10 DEG C are cooled to, carnosine, oligopeptides -1, oligopeptides -3, oligopeptides -5 is sequentially added, is uniformly mixed.
Sampling observation outward appearance, color and luster, smell, viscosity, pH value, meet quality control standard QB/T2660 requirements, you can mistake
Material is filtered out, is positioned over Low temperature refrigerator, and samples and does the inspection of semifinished product, qualified i.e. filling to lyophilized bottle (cillin bottle or Butting bottle)
In, filling amount 3ml.It is put into afterwards in vacuum freeze drier, freeze-drying curve is set, is lyophilized into freeze-dried powder.
Elite solvent：
Weighed by formula and singly weigh each component to respective container.
At room temperature, pure water is added in vacuum emulsifying pot, under stirring, sequentially add glycerine, EDTA-2Na,
Saccharomyces cerevisiae (SACCHAROMYCES CEREVIS extracts, peppery peppermint (MENTHA PIPERITA) extract, upland cotton
(GOSSYPIUM HIRSUTUM) extract, alfalfa (MEDICAGO SATIVA) extract, Wild soybean (GLYCINE SOJA)
Albumen, alfalfa (MEDICAGO SATIVA) extract, hydrolysis Candida (CANDIDA SAITOANA) extract, nerve
Acid amides 3, a material is often added, interval stirring 2-3 minutes, after adding, is stirred for being completely dissolved within 20 minutes uniformly.
Addition decoyl hydroximic acid (and) hexylene glycol (and) 1,3-PD, continue stirring 10 minutes, be well mixed.
Sampling observation outward appearance, color and luster, smell, viscosity, pH value, meet quality control standard QB/T2660 requirements, you can mistake
Material is filtered out, stands and samples afterwards and do the inspection of semifinished product, it is qualified filling into Packaging Bottle.
When in use, the Packaging Bottle of freeze-dried powder and elite solvent can be opened at room temperature, uniform freeze-dried mixed powder and elite
Ocular cell of the present invention is obtained after solvent and assigns anti-ageing Essence living.
Embodiment 2
A kind of ocular cell assigns anti-ageing Essence living, using freeze-dried powder and elite solvent formula formulation, by mass percent
Composition composition：
Elite solvent：
Preparation method comprises the following steps that：
Freeze-dried powder：
Weighed by formula and singly weigh each component to respective container.
At room temperature, pure water is added in vacuum emulsifying pot, adds Sodium Hyaluronate, be heated to temperature while stirring
60 DEG C, homogeneous 3-4 minutes are beaten, stirring and dissolving is uniform, sequentially adds mannitol, trehalose, stirring to being uniformly dissolved.
Less than 10 DEG C are cooled to, carnosine, oligopeptides -1, oligopeptides -3, oligopeptides -5 is sequentially added, is uniformly mixed.
Sampling observation outward appearance, color and luster, smell, viscosity, pH value, meet quality control standard QB/T2660 requirements, you can mistake
Material is filtered out, is positioned over Low temperature refrigerator, and samples and does the inspection of semifinished product, qualified i.e. filling to lyophilized bottle (cillin bottle or Butting bottle)
In, filling amount 3ml.It is put into afterwards in vacuum freeze drier, freeze-drying curve is set, is lyophilized into freeze-dried powder.
Elite solvent：
Weighed by formula and singly weigh each component to respective container.
At room temperature, pure water is added in vacuum emulsifying pot, under stirring, sequentially add glycerine, EDTA-2Na,
Saccharomyces cerevisiae (SACCHAROMYCES CEREVIS extracts, peppery peppermint (MENTHA PIPERITA) extract, upland cotton
(GOSSYPIUM HIRSUTUM) extract, alfalfa (MEDICAGO SATIVA) extract, Wild soybean (GLYCINE SOJA)
Albumen, alfalfa (MEDICAGO SATIVA) extract, hydrolysis Candida (CANDIDA SAITOANA) extract, nerve
Acid amides 3, a material is often added, interval stirring 2-3 minutes, after adding, is stirred for being completely dissolved within 20 minutes uniformly.
Addition decoyl hydroximic acid (and) hexylene glycol (and) 1,3-PD, continue stirring 10 minutes, be well mixed.
Sampling observation outward appearance, color and luster, smell, viscosity, pH value, meet quality control standard QB/T2660 requirements, you can mistake
Material is filtered out, stands and samples afterwards and do the inspection of semifinished product, it is qualified filling into Packaging Bottle.
When in use, the Packaging Bottle of freeze-dried powder and elite solvent can be opened at room temperature, uniform freeze-dried mixed powder and elite
Ocular cell of the present invention is obtained after solvent and assigns anti-ageing Essence living.
Embodiment 3
A kind of ocular cell assigns anti-ageing Essence living, using freeze-dried powder and elite solvent formula formulation, by mass percent
Composition composition：
Elite solvent：
Preparation method comprises the following steps that：
Freeze-dried powder：
Weighed by formula and singly weigh each component to respective container.
At room temperature, pure water is added in vacuum emulsifying pot, adds Sodium Hyaluronate, be heated to temperature while stirring
60 DEG C, homogeneous 3-4 minutes are beaten, stirring and dissolving is uniform, sequentially adds mannitol, trehalose, stirring to being uniformly dissolved.
Less than 10 DEG C are cooled to, carnosine, oligopeptides -1, oligopeptides -3, oligopeptides -5 is sequentially added, is uniformly mixed.
Sampling observation outward appearance, color and luster, smell, viscosity, pH value, meet quality control standard QB/T2660 requirements, you can mistake
Material is filtered out, is positioned over Low temperature refrigerator, and samples and does the inspection of semifinished product, qualified i.e. filling to lyophilized bottle (cillin bottle or Butting bottle)
In, filling amount 3ml.It is put into afterwards in vacuum freeze drier, freeze-drying curve is set, is lyophilized into freeze-dried powder.
Elite solvent：
Weighed by formula and singly weigh each component to respective container.
At room temperature, pure water is added in vacuum emulsifying pot, under stirring, sequentially add glycerine, EDTA-2Na,
Saccharomyces cerevisiae (SACCHAROMYCES CEREVIS extracts, peppery peppermint (MENTHA PIPERITA) extract, upland cotton
(GOSSYPIUM HIRSUTUM) extract, alfalfa (MEDICAGO SATIVA) extract, Wild soybean (GLYCINE SOJA)
Albumen, alfalfa (MEDICAGO SATIVA) extract, hydrolysis Candida (CANDIDA SAITOANA) extract, nerve
Acid amides 3, a material is often added, interval stirring 2-3 minutes, after adding, is stirred for being completely dissolved within 20 minutes uniformly.
Addition decoyl hydroximic acid (and) hexylene glycol (and) 1,3-PD, continue stirring 10 minutes, be well mixed.
Sampling observation outward appearance, color and luster, smell, viscosity, pH value, meet quality control standard QB/T2660 requirements, you can mistake
Material is filtered out, stands and samples afterwards and do the inspection of semifinished product, it is qualified filling into Packaging Bottle.
When in use, the Packaging Bottle of freeze-dried powder and elite solvent can be opened at room temperature, uniform freeze-dried mixed powder and elite
Ocular cell of the present invention is obtained after solvent and assigns anti-ageing Essence living.
The preferred embodiments of the present invention are above are only, any restrictions effect is not played to the present invention.Belonging to any
Those skilled in the art, in the range of technical scheme is not departed from, to the invention discloses technical scheme and
Technology contents make the variation such as any type of equivalent substitution or modification, belong to the content without departing from technical scheme, still
Belong within protection scope of the present invention.
Claims (8)
1. a kind of ocular cell assigns anti-ageing Essence living, it is characterised in that using freeze-dried powder and elite solvent formula formulation.
2. ocular cell according to claim 1 assigns anti-ageing Essence living, it is characterised in that the freeze-dried powder includes：It is sweet
Reveal sugar alcohol, trehalose, carnosine, Sodium Hyaluronate, oligopeptides -1, oligopeptides -3, oligopeptides -5 and pure water；The elite solvent includes：It is sweet
Oil, brewer's yeast fungus extract, peppery mint extract, upland cotton extract, Alfalfa P.E, Wild soybean albumen, hydrolysis are false
Silk yeast extract, preservative, through acid amides 3, EDTA-2Na and pure water.
3. ocular cell according to claim 2 assigns anti-ageing Essence living, it is characterised in that the preservative is decoyl hydroxyl
Oxime acid, hexylene glycol, the one of which of 1,3- propane diols or two or more any combination.
4. ocular cell according to claim 2 assigns anti-ageing Essence living, it is characterised in that with following mass percent
Composition is formed：Mannitol 1.5-3.5；Trehalose 0.5-1.5；Carnosine 0.05-0.2；Sodium Hyaluronate 0.05-0.15；Oligopeptides-
10.04-0.08；Oligopeptides -30.008-0.015；Oligopeptides -50.008-0.015；Glycerine 2.0-5.0；Brewer's yeast fungus extract
2.0-5.0；Peppery mint extract 2.0-5.0；Upland cotton extract 2.0-4.0；Alfalfa P.E 2.0-4.0；Wild soybean egg
White 1.0-4.0；Hydrolyze Candida extract 0.5-3.0；Preservative 0.5-1.0；Cer NP 0.3-0.5；EDTA-
2Na0.05-0.1；Pure water surplus.
5. ocular cell according to claim 4 assigns anti-ageing elite liquid and preparation method thereof living, it is characterised in for preparing freeze-dried powder
With elite solvent, then uniformly mix and be made after the freeze-dried powder and the elite solvent.
6. ocular cell according to claim 4 assigns anti-ageing elite liquid and preparation method thereof living, it is characterised in that prepared by freeze-dried powder
Comprise the following steps：
Weighed by formula and singly weigh each component to respective container.
At room temperature, pure water is added in vacuum emulsifying pot, adds Sodium Hyaluronate, be heated to temperature 60 while stirring
DEG C, homogeneous 3-4 minutes are beaten, stirring and dissolving is uniform, sequentially adds mannitol, trehalose, stirring to being uniformly dissolved；
Less than 10 DEG C are cooled to, carnosine, oligopeptides -1, oligopeptides -3, oligopeptides -5 is sequentially added, is uniformly mixed；
Filtering and discharging after the assay was approved, in filling to lyophilized bottle (cillin bottle or Butting bottle), filling amount 3ml；It is put into vacuum refrigeration
In drying machine, freeze-drying curve is set, is lyophilized into freeze-dried powder.
7. ocular cell according to claim 4 assigns anti-ageing elite liquid and preparation method thereof living, it is characterised in that elite solvent system
It is standby to comprise the following steps：
Weighed by formula and singly weigh each component to respective container；
At room temperature, pure water is added in vacuum emulsifying pot, under stirring, sequentially adds glycerine, EDTA-2Na, beer
Yeast extract, peppery mint extract, upland cotton extract, Alfalfa P.E, Wild soybean albumen, Alfalfa P.E,
Candida extract, Cer NP are hydrolyzed, a material is often added, interval stirring 2-3 minutes, after adding, is stirred for 20 minutes
It is completely dissolved uniformly；Preservative is added, continues stirring 10 minutes, is well mixed；
Filtering and discharging after the assay was approved, stand and sample afterwards and do the inspection of semifinished product, it is filling into Packaging Bottle after qualified.
8. the ocular cell according to claim 6 or 7 assigns anti-ageing elite liquid and preparation method thereof living, it is characterised in that examines bag
Include：Sampling observation outward appearance, color and luster, smell, viscosity, pH value, meet quality control standard QB/T2660 requirements.
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| CN108524381A (en) * | 2018-07-16 | 2018-09-14 | 广东卓明仕生物科技有限公司 | It is a kind of to be used to repair composition of skin barrier and its preparation method and application |
| CN109589276A (en) * | 2019-01-23 | 2019-04-09 | 广州帆航贸易有限公司 | A kind of active peptide composition is preparing the application method in beauty product |
| CN110179728A (en) * | 2019-05-13 | 2019-08-30 | 广州丽彦妆生物科技有限公司 | A kind of edible freeze-dried powder preparation and preparation method thereof |
| CN110496067A (en) * | 2019-09-29 | 2019-11-26 | 海口惠元生物科技有限公司 | A kind of anti-wrinkle composition and its preparation method and application |
| CN111588656A (en) * | 2020-04-30 | 2020-08-28 | 杭州谦美化妆品有限公司 | Application of symbiotic fermentation product of hydrolyzed candida and saccharomyces cerevisiae |
| CN111991278A (en) * | 2020-09-30 | 2020-11-27 | 珠海美逸生物科技有限公司 | Composition with skin barrier repairing effect and preparation method and application thereof |
| CN113712844A (en) * | 2021-08-19 | 2021-11-30 | 广州元基生物科技有限公司 | Preparation method and application of freeze-dried powder with sensitive skin barrier repair effect |
| CN113750030A (en) * | 2021-10-11 | 2021-12-07 | 李俊 | Anti-aging essence containing exosomes and preparation method thereof |
| CN114366698A (en) * | 2021-11-23 | 2022-04-19 | 湖北省麦诗特生物科技有限公司 | Anti-aging composition, preparation method thereof and application thereof in cosmetics |
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| CN116392435A (en) * | 2023-04-14 | 2023-07-07 | 广西下班乐生物科技有限公司 | Cosmetic composition with effects of brightening and beautifying skin |
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| CN110496067A (en) * | 2019-09-29 | 2019-11-26 | 海口惠元生物科技有限公司 | A kind of anti-wrinkle composition and its preparation method and application |
| CN111588656A (en) * | 2020-04-30 | 2020-08-28 | 杭州谦美化妆品有限公司 | Application of symbiotic fermentation product of hydrolyzed candida and saccharomyces cerevisiae |
| CN111991278A (en) * | 2020-09-30 | 2020-11-27 | 珠海美逸生物科技有限公司 | Composition with skin barrier repairing effect and preparation method and application thereof |
| CN113712844A (en) * | 2021-08-19 | 2021-11-30 | 广州元基生物科技有限公司 | Preparation method and application of freeze-dried powder with sensitive skin barrier repair effect |
| CN113750030A (en) * | 2021-10-11 | 2021-12-07 | 李俊 | Anti-aging essence containing exosomes and preparation method thereof |
| CN114366698A (en) * | 2021-11-23 | 2022-04-19 | 湖北省麦诗特生物科技有限公司 | Anti-aging composition, preparation method thereof and application thereof in cosmetics |
| CN114366698B (en) * | 2021-11-23 | 2024-01-26 | 湖北省麦诗特生物科技有限公司 | Anti-aging composition, preparation method thereof and application thereof in cosmetics |
| CN115068356A (en) * | 2022-07-12 | 2022-09-20 | 深圳市诗婷泰格生物科技有限公司 | Oligopeptide repairing essence |
| CN116392435A (en) * | 2023-04-14 | 2023-07-07 | 广西下班乐生物科技有限公司 | Cosmetic composition with effects of brightening and beautifying skin |
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