CN107469406A - One kind pressurization solid-phase extraction device - Google Patents
One kind pressurization solid-phase extraction device Download PDFInfo
- Publication number
- CN107469406A CN107469406A CN201710805662.XA CN201710805662A CN107469406A CN 107469406 A CN107469406 A CN 107469406A CN 201710805662 A CN201710805662 A CN 201710805662A CN 107469406 A CN107469406 A CN 107469406A
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- China
- Prior art keywords
- phase extraction
- solid
- cylindrical drum
- taper cone
- cone barrel
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- 238000002414 normal-phase solid-phase extraction Methods 0.000 title claims abstract description 41
- 238000007789 sealing Methods 0.000 claims description 5
- 230000001737 promoting effect Effects 0.000 claims 1
- 238000000605 extraction Methods 0.000 abstract description 12
- 238000002474 experimental method Methods 0.000 abstract description 5
- 230000008859 change Effects 0.000 abstract description 4
- 239000012535 impurity Substances 0.000 abstract description 4
- 230000009467 reduction Effects 0.000 abstract description 4
- 230000000903 blocking effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000012071 phase Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 239000000686 essence Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 238000004804 winding Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/16—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
- B01D15/163—Pressure or speed conditioning
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Extraction Or Liquid Replacement (AREA)
Abstract
The present invention provides a kind of pressurization solid-phase extraction device, including solid-phase extraction column, inflator is removably connected with above the solid-phase extraction column, rack provided with piston and the promotion piston in the inflator, the cylindrical drum and taper cone barrel that inflator side right angle setting is rotatably connected, the taper cone barrel is provided with gear, the gear engages with the rack, the cylindrical drum and the taper cone barrel are mutually driven by drawstring, torque spring is provided with the cylindrical drum, the torque spring is used to drive the cylindrical drum.By changing the taper of cone, constant pressure or the pressure gradually increased can be obtained.To be detachably connected between inflator and solid-phase extraction column, need to select different inflators according to different experiments, you can obtain the pressure of different situations of change, avoid the problem of pressure reduction and impurity gradually block and causes flow velocity gradually to weaken in extraction process.
Description
Technical field
The present invention relates to a kind of SPE column device, more particularly to a kind of pressurization solid-phase extraction device.
Background technology
SPE is the purification means commonly used in chemical experiment, and it is using more and more extensive.In use, by
It is more in sample substrate impurity, the problems such as impurity blocks in extraction process is caused, the flow velocity for blocking extraction weakens, and one is needed for this
It is individual to be pressurizeed in extraction process.Pressurization is carried out to device using spring element at present can be because of pressure process spring deformation
Amount, which is gradually reduced, causes extraction flow velocity unstable, and the cost being controlled using devices such as force (forcing) pumps is again excessively high, therefore needs
A kind of simple device is wanted, can keep applying constant pressure or gradually honest pressure in extraction process.
The content of the invention
For mirror with this, the present invention proposes a kind of pressurization solid-phase extraction device, can ensure constant pressure during extraction
Power or the pressure gradually increased, simple in construction, cost is cheap.
The technical proposal of the invention is realized in this way：One kind pressurization solid-phase extraction device, including solid-phase extraction column, it is described
Inflator is detachably connected above solid-phase extraction column, piston is provided with the inflator and promotes the rack of the piston, the inflator
The cylindrical drum and taper cone barrel that side right angle setting is rotatably connected, the taper cone barrel are provided with gear, the gear and the rack
Engagement, the cylindrical drum and the taper cone barrel are mutually driven by drawstring, and torque spring, the torsion are provided with the cylindrical drum
Spring is used to drive the cylindrical drum.
Further, the solid-phase extraction column side is provided with sleeve, and the cylindrical drum and the taper cone barrel are located at described
In sleeve.
Further, the fixed column of the fixed torque spring, the fixed column and the set are provided with the taper cone barrel
Cylinder is rotatably connected, and the frictional force of the fixed column and the sleeve is more than the acrotorque of torque spring, and the fixed column is set
There is knob.
Further, the surface of the sleeve is provided with scale, and the surface of the knob is provided with indicator.
Further, the solid-phase extraction column both sides are provided with support bar.
Further, the solid-phase extraction column is connected through a screw thread with the inflator, and junction is provided with sealing ring.
Further, the taper cone barrel and the cylindrical outer tube surface are equipped with helical groove.
Compared with prior art, the beneficial effects of the invention are as follows：By changing the taper of cone, can obtain constant
Pressure or the pressure gradually increased.To be detachably connected between inflator and solid-phase extraction column, need to select according to different experiments
Select different inflators, you can obtain the pressure of different situations of change, avoid pressure reduction and impurity in extraction process from gradually blocking up
The problem of filling in and causing flow velocity gradually to weaken.
Brief description of the drawings
Fig. 1 is a kind of pressurization solid-phase extraction device structural representation of the embodiment of the present invention；
Fig. 2 is a kind of pressurization solid-phase extraction device structural representation of the embodiment of the present invention；
Fig. 3 is sleeve, cylindrical drum and the taper cone barrel structural representation of the embodiment of the present invention；
In figure, 1 solid-phase extraction column, 2 inflators, 3 pistons, 4 racks, 5 cylindrical drums, 6 taper cone barrels, 7 gears, 8 drawstrings, 9 torsion
Spring, 10 sleeves, 11 fixed columns, 12 knobs, 13 scales, 14 indicators, 15 support bars, 16 sealing rings, 17 screw threads, 18 spirals are recessed
Groove.
Embodiment
In order to be best understood from the technology of the present invention content, specific embodiment is provided below, and with reference to accompanying drawing the present invention is done into
The explanation of one step.
Referring to Fig. 1 to 3, a kind of pressurization device of solid-phase extraction column 1 provided by the invention, including solid-phase extraction column 1, it is described solid
The top of phase extraction column 1 is detachably connected inflator 2, is provided with piston 3 in the inflator 2 and promotes the rack 4 of the piston 3, described
The cylindrical drum 5 and taper cone barrel 6 that the side right angle setting of inflator 2 is rotatably connected, the cylindrical drum 5 and the axis of rotation phase of taper cone barrel 6
Mutually parallel, the taper cone barrel 6 is provided with gear 7, and the gear 7 engages with the rack 4, the cylindrical drum 5 and the taper cone barrel 6
Mutually driven by drawstring 8, torque spring 9 is provided with the cylindrical drum 5, the torque spring 9 is used to drive the cylindrical drum
5。
During pressurization, torque spring 9 drives cylindrical drum 5 to rotate, and cylindrical drum 5 drives taper cone barrel 6 to rotate by drawstring 8, cylinder
Gear 7 on cylinder 5 drives rack 4 to be pressed downward piston 3, and air pressure rises and solid-phase extraction column 1 is pressurizeed in inflator 2.After extraction,
Rack 4 is pulled up, piston 3 moves upwards, is rotated with the drive gear 7 of hour rack 4, the taper cone barrel 6 being connected with gear 7 rotates simultaneously
Cylindrical drum 5 is driven by drawstring 8, cylindrical drum 5, which rotates, tightens torque spring 9.During torque spring 9 releases energy,
The reduction of the deformation quantity of torque spring 9, elastic force also reduce therewith, while cylindrical drum 5 rotates, and drawstring 8 is opened from one end of cylindrical drum 5
Begin the other end of the volume to cylindrical drum 5, and one end of taper cone barrel 6 starts to discharge drawstring 8, with the release of drawstring 8, cylindrical drum 5 and circle
Gearratio between cone cylinder 6 gradually increases, and reaches a gradual labour-saving structure, for compensating the force variation of deformation reduction.
According to the different taper cone barrels 6 for needing to design different tapers, the curve that different dynamics changes can be obtained, you can to obtain perseverance
Power, change reinforcing and change subtract power, thus obtain the pressurization SPE column device of different specifications, and can be in pressurization solid-phase extraction column
Device subscript, which carves, to be come, and different size is selected in different extraction experiments.Inflator 2 is to be detachably connected with solid-phase extraction column 1, can
Different inflators 2 is selected to be enclosed on solid-phase extraction column 1.
Specifically, the side of solid-phase extraction column 1 is provided with sleeve 10, and the cylindrical drum 5 and the taper cone barrel 6 are located at institute
State in sleeve 10, play a part of protection, prevent the debris such as dust enter from resulting in blockage.Sleeve 10 can design bearing block, will
Cylindrical drum 5 and taper cone barrel 6 are arranged in bearing block, improve the stability of device.
Specifically, the fixed column 11 of the fixed torque spring 9, the fixed column 11 and institute are provided with the taper cone barrel 6
State sleeve 10 to be rotatably connected, the frictional force of the fixed column 11 and the sleeve 10 is more than the acrotorque of torque spring 9, institute
State fixed column 11 and be provided with knob 12.The torsion that fixed column 11 and the frictional force of sleeve 10 are more than torque spring 9 can avoid torsion
Spring 9 is pulled by spring and inverted, and different initial initial tension of spring can be obtained by adjusting knob 12, and then obtain different
Rate of extraction, adapt to different requirement of experiment.
Specifically, the surface of the sleeve 10 is provided with scale 13, and the surface of the knob 12 is provided with indicator 14.In scale
Different scales 13 is marked on 13, it is necessary to can intuitively read initial dynamics during strength of adjustment.When the pressurization device of solid-phase extraction column 1
When being pressurizeed for constant force, pressurization dynamics can be read directly on scale 13.Further, scale can be provided with rack 4, can be used
Scale reading on rack 4 is multiplied by the scale reading on sleeve 10, you can calculates real time stress dynamics.
Specifically, the both sides of solid-phase extraction column 1 are provided with support bar 15.It is easy to the fixed pressurization device of solid-phase extraction column 1.
Specifically, the solid-phase extraction column 1 is connected with the inflator 2 by screw thread 17, and junction is provided with sealing ring 16.
Screw connection structure is close, while can effectively be sealed provided with sealing ring 16 in junction, avoids gas leakage.
Specifically, the taper cone barrel 6 and the outer surface of the cylindrical drum 5 are equipped with helical groove 18.Drawstring 8 is facilitated to wind,
Prevent drawstring winding dislocation.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
God any modification, equivalent substitution and improvements made etc., should be included in the scope of the protection with principle.
Claims (7)
1. one kind pressurization solid-phase extraction device, it is characterised in that：It is detachable above the solid-phase extraction column including solid-phase extraction column
Inflator is connected, is rotatably connected provided with piston and the rack for promoting the piston, inflator side right angle setting in the inflator
The cylindrical drum and taper cone barrel connect, the taper cone barrel are provided with gear, and the gear engages with the rack, the cylindrical drum and described
Taper cone barrel is mutually driven by drawstring, and torque spring is provided with the cylindrical drum, and the torque spring is used to drive the cylinder
Cylinder.
A kind of 2. pressurization solid-phase extraction device as claimed in claim 1, it is characterised in that：The solid-phase extraction column side is provided with
Sleeve, the cylindrical drum and the taper cone barrel are in the sleeve.
A kind of 3. pressurization solid-phase extraction device as claimed in claim 2, it is characterised in that：Fixed institute is provided with the taper cone barrel
The fixed column of torque spring is stated, the fixed column is rotatably connected with the sleeve, the fixed column and the friction of the sleeve
Power is more than the acrotorque of the torque spring, and the fixed column is provided with knob.
A kind of 4. pressurization solid-phase extraction device as claimed in claim 3, it is characterised in that：The surface of the sleeve, which is provided with, carves
Degree, the surface of the knob is provided with indicator.
A kind of 5. pressurization solid-phase extraction device as claimed in claim 1, it is characterised in that：The solid-phase extraction column both sides are provided with
Support bar.
A kind of 6. pressurization solid-phase extraction device as claimed in claim 1, it is characterised in that：The solid-phase extraction column and the gas
Cylinder is connected through a screw thread, and junction is provided with sealing ring.
A kind of 7. pressurization solid-phase extraction device as claimed in claim 1, it is characterised in that：The taper cone barrel and the cylindrical drum
Outer surface is equipped with helical groove.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710805662.XA CN107469406B (en) | 2017-09-08 | 2017-09-08 | A kind of pressurization solid-phase extraction device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710805662.XA CN107469406B (en) | 2017-09-08 | 2017-09-08 | A kind of pressurization solid-phase extraction device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107469406A true CN107469406A (en) | 2017-12-15 |
| CN107469406B CN107469406B (en) | 2018-06-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710805662.XA Active CN107469406B (en) | 2017-09-08 | 2017-09-08 | A kind of pressurization solid-phase extraction device |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108478229A (en) * | 2018-04-27 | 2018-09-04 | 海口市人民医院（中南大学湘雅医学院附属海口医院） | CT examining table convenient to special position is put |
| CN108849077A (en) * | 2018-06-29 | 2018-11-23 | 海南润达现代农业股份有限公司 | A kind of slow-witted fruit device and method suitable for small-sized melon three-dimensional culture |
| CN109443875A (en) * | 2018-12-10 | 2019-03-08 | 华南农业大学 | A kind of Solid Phase Extraction pressure aid device and system |
| CN109675343A (en) * | 2018-12-07 | 2019-04-26 | 天津迪沃特生物电子科技有限公司 | A kind of method and device extracted and/or purify |
| CN110441218A (en) * | 2019-08-30 | 2019-11-12 | 海南方能测试技术有限公司 | A kind of concrete permeable detection device and detection method |
| CN111443074A (en) * | 2020-05-11 | 2020-07-24 | 厦门大学 | Automatic online pretreatment and Raman detection device and method |
| CN114208452A (en) * | 2021-12-30 | 2022-03-22 | 安徽理工大学 | A bean seeder |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108478229A (en) * | 2018-04-27 | 2018-09-04 | 海口市人民医院（中南大学湘雅医学院附属海口医院） | CT examining table convenient to special position is put |
| CN108478229B (en) * | 2018-04-27 | 2024-09-20 | 海口市人民医院（中南大学湘雅医学院附属海口医院） | CT examining table convenient for positioning in special body position |
| CN108849077A (en) * | 2018-06-29 | 2018-11-23 | 海南润达现代农业股份有限公司 | A kind of slow-witted fruit device and method suitable for small-sized melon three-dimensional culture |
| CN109675343A (en) * | 2018-12-07 | 2019-04-26 | 天津迪沃特生物电子科技有限公司 | A kind of method and device extracted and/or purify |
| CN109443875A (en) * | 2018-12-10 | 2019-03-08 | 华南农业大学 | A kind of Solid Phase Extraction pressure aid device and system |
| CN110441218A (en) * | 2019-08-30 | 2019-11-12 | 海南方能测试技术有限公司 | A kind of concrete permeable detection device and detection method |
| CN111443074A (en) * | 2020-05-11 | 2020-07-24 | 厦门大学 | Automatic online pretreatment and Raman detection device and method |
| CN111443074B (en) * | 2020-05-11 | 2021-08-31 | 厦门大学 | Automatic online pretreatment and Raman detection device and method |
| CN114208452A (en) * | 2021-12-30 | 2022-03-22 | 安徽理工大学 | A bean seeder |
Also Published As
| Publication number | Publication date |
|---|---|
| CN107469406B (en) | 2018-06-22 |
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