CN107468621B - Allergy-relieving skin-care emulsion and preparation method thereof - Google Patents
Allergy-relieving skin-care emulsion and preparation method thereof Download PDFInfo
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- CN107468621B CN107468621B CN201710885775.5A CN201710885775A CN107468621B CN 107468621 B CN107468621 B CN 107468621B CN 201710885775 A CN201710885775 A CN 201710885775A CN 107468621 B CN107468621 B CN 107468621B
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Abstract
The invention discloses a allergy-relieving skin-care emulsion, which comprises 100g of the following formula: 2.6-2.8 g of polyglycerol-2 stearate, 5.9-6.0 g of jojoba oil, 3.4-3.6 g of plant squalane, 0.5-0.6 g of shea butter, 0.15g of vitamin E, 3.8-4.0 g of glycerol, 0.05g of sodium phytate, 0.03g of sodium hyaluronate, 1.8-2.0 g of trehalose and SolagumTM0.28-0.32 g of AX, 0.7-0.8 g of cetearyl olive oleate, 0.5g of jasmonate, 0.5g of 1, 2-hexanediol, 0.5g of water-soluble ceramide SK-INFLUX, 0.5-1.0 g of chlorpheniramine maleate, 0.1-0.2 g of chlorpheniramine maleate, 1.0-2.0 g of perhexiline and 0.05g of rose essence; the balance being deionized water. The invention also discloses a preparation method of the composition.
Description
Technical Field
The invention relates to a skin care product (allergy-relieving skin care emulsion) of allergy-relieving emulsion and a preparation method thereof.
Background
Sensitive skin is a skin condition where the skin can react excessively to environmental factors. The reasons for the generation of sensitive skin are complex, external sensitive sources are various, and many sensitive sources are difficult to detect. Menstrual cycle, climate change, air change, cleansing products, personal care products, and clothing abrasion all contribute to the above sensitive skin condition. All of the above factors may be extrinsic factors that cause sensitive skin. However, from the internal cause, the main reasons are the following 3 aspects: keratinocyte reduces thinning of stratum corneum, thereby causing skin barrier damage; lipid imbalance between stratum corneum cells; neurobiological factors lead to alterations in nerve cells, such as hyperactivity of the neural ion channel TRPV-1. When human skin is in a sensitive skin state, hypersensitive reaction can occur when the skin is contacted with substances such as cosmetics, soap or sun-screening agents, and particularly, the skin condition is worse after insolation or when the temperature is too cold. In the sensitive skin state, the skin may have itching, burning, tingling or tightness. The skin may show erythema, dryness, rashes, and even strong inflammatory symptoms such as pimples.
The mechanism of the sensitive skin is developed to carry out the relaxing formula design, and the main purposes are to relieve the sensitive symptom of the skin, relieve the problem of dry skin and reduce the stabbing pain, the tightening feeling and the itching feeling; the problem of sensitive skin is solved from the internal reason, the use of essence, preservative and pigment is reduced in the formula, and effective moisturizing substances are added; adding an effective repairing substance. The sensitive skin is well cared, the sensitive skin is effectively moisturized under the safe condition, the TEWL value of the skin is reduced, and meanwhile, some allergy relieving components and ion channel inhibitors are properly added to relieve the state of the sensitive skin.
The existing skin care products with anti-allergy effects at present comprise:
1. the invention patent with application number 2016108272060, namely a repair emulsion focusing on sensitive muscle root sources, a preparation method and application thereof, comprises the following raw materials in percentage by mass: 0.8-1.5% of potassium cetyl phosphate, 0.2-1% of sodium bis (lauramidoglutamine) lysine, 2-10% of jojoba seed oil, 3-10% of glycerol, 1-2% of cetearyl alcohol, 1-2.5% of polydimethylsiloxane, 1-2% of hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, 0.2-2% of Dekoku 100, 1-3% of D-panthenol, 2-6% of plant propylene glycol, 5-6% of 1, 2-pentanediol, 1-2% of water-soluble ceramide, 0.5-2% of immortal, 0.5-1% of Demin, 0.5-2% of gentiana scabra bungeana, 0.05-0.5% of cell factor stock solution and the balance of water.
2. The invention patent with application number 2016110225833 discloses a multi-effect mild moisturizer containing plant lactobacillus fermented rice, which comprises the following raw materials in percentage by mass: purifying water: 70% -87%, allantoin: 0.1% -0.2%, EDTA-2 NA: 0.02-0.10%; glycerol: 1% -2%, 1, 3-propanediol: 2% -5%, carbomer: 0.05-0.1%, 0.1-0.5% of acryloyl dimethyl ammonium taurate/behenyl alcohol polyether-25 methacrylate crosslinking polymer: sodium hyaluronate: 0.01% -0.09%, tremella sporophore extract: 0.01 to 0.05 percent; lactobacillus/rice fermentation product/maltitol/arginine: 1% -3%; squalane: 2% -8%, jojoba seed oil: 1% -5%, white chinlon oil: 0.5% -2%, isononyl isononanoate: 0.5% -2%, polydimethylsiloxane: 0.5% -2%, phytosterol/octyldodecanol lauroyl glutamate: 0.1% -0.5%, shea butter: 0.3% -0.8%, double seed grease of Chinese buckeye wing: 0.5% -2%, cetearyl alcohol: 1% -3%, tocopheryl acetate: 0.05% -0.2%, C14-22 alcohol/C12-20 alkyl glucoside: 0.8% -2%, hydrogenated lecithin: 0.1% -0.5%, glyceryl caprylate: 0.05% -0.2%; 1, 2-hexanediol: 0.3% -0.8%, 1.2-pentanediol: 0.3% -0.8%, menthone: 0.1% -0.5%; sodium hydroxide: 0.01% -0.05%, niacinamide: 0.5% -2%, dipotassium glycyrrhizinate: 0.01% -0.1%, phenoxyethanol: 0.2 to 0.5 percent.
3. The invention patent with application number of 201610521890X discloses a mountain apricot eucommia bark moisturizing cream and a preparation method thereof, and the mountain apricot eucommia bark moisturizing cream comprises the following raw materials in percentage by mass: 2.0-4.0% of a mixture of cetearyl glucoside and cetearyl alcohol, 0.48-0.52% of a mixture of PEG-100 stearate and glyceryl stearate, 1.5-2.5% of cetearyl alcohol, 1.0-2.0% of polydimethylsiloxane, 3-6% of caprylic/capric triglyceride, 1.5-2.5% of a mixture of apricot oil and eucommia oil, 0.3-0.6% of VE acetate, 1.5-2.5% of shea butter, 3-7% of ethylhexyl palmitate, 3-5% of mineral oil, 0.09-0.11% of methyl hydroxybenzoate, 58.85-77.85% of water, 0.2-0.4% of carbomer, 2-4% of glycerol, 1.5-2.5% of propylene glycol, 0.09-0.11% of xanthan gum, 0.2-0.36% of triethanolamine, 0.2-0.4% of phenoxyethanol and ethylhexyl glycerol, 0.1-0.2% of jasmonate, 0.015% of tannin, 0.09-0.11% of a collagen solution, and 0.15% of a collagen solution.
Disclosure of Invention
The invention aims to solve the technical problem of providing a sedative emulsion product for concentrating and soothing sensitive skin and a preparation method thereof.
In order to solve the technical problems, the invention provides a allergy-relieving skin-care emulsion, wherein each 100g of the allergy-relieving skin-care emulsion comprises the following components in percentage by weight:
polyglycerol-2 stearate (Polyaquol)TM2W) 2.6-2.8 g, jojoba oil 5.9-6.0 g, plant squalane 3.4-3.6 g, shea butter 0.5-0.6 g, vitamin E0.15g, glycerin 3.8-4.0 g, sodium phytate 0.05g, sodium hyaluronate 0.03g, trehalose 1.8-2.0 g, and SolagamTM0.28-0.32 g of AX, 0.7-0.8 g of cetearyl olive oleate (Olivem1000), 0.5g of carithamine, 0.5g of 1, 2-hexanediol, 0.5g of water-soluble ceramide SK-INFLUX and 0.5g of chlorpheniramine maleate
) 0.5-1.0 g, Xin Min Shu (Xin Min Shu)
100) 0.1-0.2 g, and is pleasant to skin (skin-friendly and pleasant)
1609) 1.0-2.0 g of rose essence liquid 0.05 g; the balance being deionized water.
As an improvement of the allergy-relieving skin care emulsion, every 100g of the allergy-relieving skin care emulsion comprises the following components in percentage by weight:
polyglycerol-2 stearate (Polyaquol)TM2W)2.7g, jojoba oil 6.0g, plant squalane 3.5g, shea butter 0.6g, vitamin E0.15g, glycerol 4.0g, sodium phytate 0.05g, sodium hyaluronate 0.03g,trehalose 2.0g, SolagumTMAX 0.3g, cetearyl olive oleate (Olivm 1000)0.8g, menthone 0.5g, 1, 2-hexanediol 0.5g, water-soluble ceramide SK-INFLUX 0.5g, DEMINGSHU
1.0g, Xin Min Shu
1000.2 g, skin caring and refreshing
1609 is 2.0g, and flos Rosae Rugosae essence is 0.05 g; the balance being deionized water.
The invention also provides a preparation method of the allergy-relieving skin-care emulsion, which comprises the following steps:
1) mixing polyglycerol-2 stearate (Polyaquol)TM2W), jojoba oil, plant squalane, shea butter and vitamin E are heated to 80 +/-5 ℃ under the stirring condition and are kept warm for 5-10 min (preferably 80 ℃ and 10min) to obtain an oil phase raw material;
2) mixing glycerol, sodium phytate, sodium hyaluronate, trehalose, and SolagumTMHeating AX, cetearyl olive oleate (Olivem1000) and deionized water to 80 +/-5 ℃ and preserving heat for 5-10 min (preferably 80 ℃ and 10 min); homogenizing for 30-40 s (preferably for 30s at 7.8 krpm) under the condition of heat preservation at 7.5-8.0 krpm; obtaining water phase raw materials;
3) pouring (immediately pouring) the oil phase raw material in the heat preservation state obtained in the step 1) into the water phase raw material in the heat preservation state obtained in the step 2), and homogenizing at 80 +/-5 ℃ at the rotating speed of 7.2-7.8 krpm for 8-10 min;
at the moment, the emulsification system has no obvious layering, the emulsion state is more uniform and stable, and the homogenization is stopped;
4) stirring the product obtained in the step 3) at the rotating speed of 250-280 rpm under the condition of stopping heating, adding the jasmone when the temperature is reduced to 60 +/-2 ℃, and adding the 1, 2-hexanediol and the water-soluble ceramide SK-INFLUX when the temperature is continuously reduced to 45 +/-2 ℃;
5) adding chlorphenamine maleate into the product obtained in the step 4)
Medicine for treating allergy
100, skin care and joyful
1609, flos Rosae Rugosae essence; continuing to mechanically stir at the rotating speed of 250-280 rpm until the temperature is cooled to the room temperature.
In the present invention, all the ingredients can be obtained in a commercially available form.
SolagumTMAX, gum arabic and xanthan gum as main ingredients;
SK-INFLUX, the main components are ceramide 3, ceramide 6II, phytosphingosine, cholesterol, water;
demin medicine
The main components are butanediol, 1, 2-pentanediol and hydroxyphenylpropionamide benzoic acid;
medicine for treating allergy
100, the main components are bisabolol and ginger extract;
skin caring and joyful
1609 mainly contains 1, 2-pentanediol and 4-tert-butylcyclohexanol.
The emulsion prepared by the method is milky white, has fine and refreshing skin feel, is not sticky and greasy in use feel, and has good moisturizing effect and allergy relieving effect. The centrifugal experiment (the centrifugal time is 30min, the rotating speed is 2000rpm) does not layer, and the emulsification system is stable. The pH value is 4.4-5.5, no change is caused when the temperature is recovered to the room temperature in a heat-resistant way (45 +/-1 ℃ and 24 hours), and no obvious change is caused when the temperature is recovered to the room temperature in a cold-resistant way (4 +/-1 ℃ and 24 hours). The freeze-thaw experiment result shows no obvious change, and the viscosity is 14000 and 35000 cp.
The allergy-relieving emulsion can be used for preparing sensitive skin cosmetics.
The invention takes Demin (having the functions of relieving itching and resisting oxidation), Xinmin (having the functions of reducing swelling and removing red and swollen erythema) and Xinfu (nerve ion channel inhibitor for eliminating heat sensation) as main allergy-relieving active ingredients. Glycerin and trehalose are matched to serve as an effective humectant, and sodium hyaluronate has good water binding capacity and can be quickly hydrated with cells to enable the skin to be full of elasticity. Meanwhile, oil from selected plants, golden jojoba oil, squalane and shea butter are added into the formula, and the structure of the oil is similar to that of skin oil, so that the moisturizing effect can be enhanced. The preservative is selected from the jasminon and the 1, 2-hexanediol to be matched for use, so that the sensitization risk is reduced. And water-soluble ceramide is also added, so that the skin barrier function is effectively repaired, and the skin barrier is helped to be reconstructed.
The usage of the allergy-relieving skin-care emulsion comprises the following steps: applying appropriate amount of the extract on skin.
The invention overcomes the defects and shortcomings of the existing cosmetics aiming at the problem of sensitive skin, and the allergy-relieving emulsion prepared by the method has the following gain effects:
(1) the allergy-relieving emulsion disclosed by the invention can effectively calm the skin aiming at the problems of relieving and repairing sensitive skin, and has multiple effects of moisturizing, repairing, relieving allergy, calming and the like; reducing skin redness, resisting redness and erythema, and relieving itching; enhancing self-repairing ability of skin, has high anti-inflammatory effect, and is suitable for sensitive skin.
(2) The allergy-relieving emulsion disclosed by the invention is simple in process and convenient to use.
(3) The invention has the advantages of excellent formula, no traditional preservative, no potential irritative allergens such as essence, pigment and the like, mild formula and no irritation.
In conclusion, the allergy-relieving repair emulsion disclosed by the invention is used for nursing sensitive skin, fundamentally caring the sensitive skin, has multiple effects of efficiently repairing, moisturizing and relieving the skin, and has a great application prospect.
Drawings
The following describes embodiments of the present invention in further detail with reference to the accompanying drawings.
FIG. 1 is a graph showing changes in the rate of increase of stratum corneum water content in a subject;
FIG. 2 is a TEWL map of a subject;
in the figure, A- - -example 1, B- - -example 2, C- - -example 3.
Detailed Description
The invention will be further described with reference to specific examples, but the scope of the invention is not limited thereto.
The formulations of examples 1-3 (per 100g of product) are shown in Table 1.
TABLE 1, EXAMPLES 1-3 recipe Table (unit g)
Example 1, a method of preparing a soothing emulsion skin care product, sequentially performing the following steps:
1) weighing PolyaquolTM2.7g of 2W, 6.0g of jojoba oil, 3.5g of plant squalane, 0.6g of shea butter and 0.15g of vitamin E are added into an oil phase pot, and the oil phase raw material is obtained by putting the oil phase pot into a constant temperature water bath box, raising the temperature to 80 ℃ and preserving the temperature for 10 min.
2) Weighing 4.0g of glycerin, 0.05g of sodium phytate, 0.03g of sodium hyaluronate, 2.0g of trehalose and SolagumTMAdding 0.3g of AX (xanthan gum and Arabic gum), 10000.8 g of Olivem and 76.72g of deionized water into a water phase pot, heating to 80 ℃, and keeping the temperature for 10 min;
at the moment, the raw materials in the water phase pot are basically dissolved, the raw materials in the water phase pot are homogenized, the rotating speed of a homogenizer is 7.8krpm, and the homogenization time is 30s, so that the water phase raw materials are obtained.
3) Immediately pouring the water phase raw material in the heat preservation state obtained in the step 2) into the oil phase raw material in the heat preservation state obtained in the step 1), and homogenizing at the temperature of 80 ℃ and the rotating speed of 7.8krpm for 10 min.
At the moment, the emulsification system has no obvious layering, and the homogenization is stopped when the emulsion state is more uniform and stable.
4) After homogenizing, stopping heating and preserving heat, carrying out mechanical stirring, rotating the speed of a stirring paddle at 280rpm, adding 0.5g of menthone when the temperature is reduced to 60 ℃, and adding 0.5g of 1, 2-hexanediol and 0.5g of SK-INFLUX when the temperature is reduced to 45 ℃;
5) adding chlorphenamine maleate into the product obtained in the step 4)
0.5g, Xin Min Shu
1000.1g, skin caring and joyful
16091.0 g, adding 0.05g rose essence. Continuing mechanical stirring, rotating the stirring paddle at the speed of 280rpm, stirring, cooling and cooling to room temperature.
The emulsion prepared in the example 1 is milky white, fine and refreshing in skin feel, non-sticky in use feel, and good in moisturizing effect and allergy relieving effect. The centrifugal experiment (the centrifugal time is 30min, the rotating speed is 2000rpm) does not layer, and the emulsification system is stable. The pH value is 5.03, the temperature can be kept (45 +/-1 ℃ and 24 hours) without any change when the temperature is restored to the room temperature, and the temperature can be kept (4 +/-1 ℃ and 24 hours) without any obvious change when the temperature is restored to the room temperature. The freeze-thaw experiment result shows no obvious change and the viscosity is 15000 cp.
Example 2, the formulation is shown in table 1, the preparation method is identical to example 1.
The emulsion prepared in the example 2 is milky white, fine and refreshing in skin feel, non-sticky in use feel, and good in moisturizing effect and allergy relieving effect. The centrifugal experiment (the centrifugal time is 30min, the rotating speed is 2000rpm) does not layer, and the emulsification system is stable. The pH value is 4.76, the temperature can be recovered to the room temperature without any change when the temperature is resistant (45 +/-1 ℃ and 24 hours), and the temperature can be recovered to the room temperature without obvious change when the temperature is resistant (4 +/-1 ℃ and 24 hours). The freeze-thaw experiment result shows no obvious change, and the viscosity is 30167 cp.
Example 3, the formulation is shown in table 1, the preparation method is identical to example 1.
The emulsion prepared in the example 3 is milky white, fine and refreshing in skin feel, non-sticky in use feel, and good in moisturizing effect and allergy relieving effect. The centrifugal experiment (the centrifugal time is 30min, the rotating speed is 2000rpm) does not layer, and the emulsification system is stable. The pH value is 4.56, the temperature can be recovered to the room temperature without any change when the temperature is heat-resistant (45 +/-1 ℃ and 24 hours), and the temperature can be recovered to the room temperature without obvious change when the temperature is cold-resistant (4 +/-1 ℃ and 24 hours). The freeze-thaw experiment result shows no obvious change and viscosity of 22500 cp.
The basic formula example is that no soothing agent is added, namely, Demin is 0g, and Xinmin is 0 g. Namely, the use of Demin comfortable, Xinmin comfortable and Xinfu comfortable in the implementation 1 is cancelled, and the weight of deionized water is correspondingly increased until the total weight is still 100 g; the rest is equivalent to embodiment 1.
Experiment I, moisture retention evaluation test:
the specific test steps are as follows:
1. the environmental temperature is controlled at 25 deg.C, and the testee can enter the room 30min before cleaning the arms, and relax.
2. The subjects were 10 in total, 1 male and 9 female. 2X 2cm on the arm of 10 subjects2Coating 0.05ml of sample in the area, wherein 5 areas are used, and one area is used as a blank control and is not coated with any product; the remaining four areas were coated with base formulation example and examples 1,2,3, respectively.
3. The test intervals are 0min, 30min, 60min, 90min and 120 min.
Stratum corneum water content was measured using the MoistureMeter SC Compact from Delfin corporation and the amount of trans-dermal water loss (TEWL) was measured using the Vapometer from Delfin corporation.
The average value is taken, and the test result of the water content increase rate of the horny layer is shown in figure 1; the TEWL test results are shown in FIG. 2.
Remarks explanation: the TEWL test results obtained in example 3 were substantially the same as those obtained in example 2.
By testing the change of the water content of the horny layer and the TEWL, the state of the skin can be really improved by applying the allergy-relieving emulsion product, and the emulsion has a certain moisturizing effect.
Experiment 2, histamine test experiment.
The experiment was carried out according to the following procedure:
1. cleaning the arm, and naturally drying.
2. At arm 2X 2cm20.05ml of a 10mg/ml histamine solution was applied to the area, and after complete absorption of the histamine solution (about 10min), the base formula and example 3 (both 0.05ml) were applied and the skin condition was recorded at different times.
The test results are given in table 2 below:
TABLE 2 comparison of the base formulation examples for painting with example 3 containing a high concentration of the phlegmatizer
Note: the skin condition was scored as shown in table 3 below, and the scrapie score was scored as shown in table 4 below.
TABLE 3 skin Condition determination criteria
TABLE 4 Pruritus rating Table
| Score value | Feeling |
| 0-1 | No itching |
| 1-2 | Mild itching |
| 2-3 | Moderate itching |
| 3-4 | Severe itching |
| 4-5 | Very scratchy |
The experiment shows that the emulsion of the basic formula example is compared with the emulsion added with high-concentration allergy-relieving components in the example 3 of the invention obviously, and the invention has good allergy-relieving effect.
Comparative examples 1-1, example 3 formulation "Deminshu
1.00g, Xin Min Shu
1000.20g, skin caring and refreshing
16092.00 g 'Demin Shu' instead
1.10g, skin caring and refreshing
16092.10g "; the rest is equivalent to example 3.
The soothing skin care emulsions obtained in example 3 and comparative examples 1-1 were subjected to histamine test experiments as described in experiment 2 above; the results obtained are shown in table 5 below.
TABLE 5 comparison of the application of the example 3 and the comparative examples 1-1 containing different concentrations of the phlegmatizer
Comparative examples 1-2, example 3 formulation "Deminshu
1.00g, Xin Min Shu
1000.20g, skin caring and refreshing
16092.00 g 'Demin Shu' instead
0.4g, Xin Min Shu
1000.20g, skin caring and refreshing
16092.60 g "; the rest is equivalent to example 3.
The soothing skin care emulsions obtained in example 3 and comparative examples 1-2 were subjected to a histamine test as described in experiment 2 above; the results obtained are shown in table 6 below.
TABLE 6 comparison of the application of the example 3 and the comparative examples 1-2 containing different concentrations of the phlegmatizer
Comparative examples 1-3, example 3 formulation "Deminshu
1.00g, Xin Min Shu
1000.20g, skin caring and refreshing
16092.00 g 'Demin Shu' instead
1.5g, Xin Min Shu
1000.20g, skin caring and refreshing
16091.5 g "; the rest is equivalent to example 3.
The soothing skin care emulsions obtained in example 3 and comparative examples 1-3 were subjected to a histamine test as described in experiment 2 above; the results obtained are described in table 7 below.
TABLE 7 comparison of the application of the example 3 and the comparative examples 1 to 3 containing different concentrations of the phlegmatizer
Comparative examples 1-4, example 3 formulation "Deminshu
1.00g, Xin Min Shu
1000.20g, skin caring and refreshing
16092.00 g 'Demin Shu' instead
0g, Xin Min Shu
1000.20g, skin caring and refreshing
16093 g "; the rest is equivalent to example 3.
The soothing skin care emulsions obtained in example 3 and comparative examples 1 to 4 were subjected to a histamine test as described in experiment 2 above; the results obtained are shown in Table 8 below.
TABLE 8 comparison of the application of the example 3 and the comparative examples 1 to 4 containing different concentrations of the phlegmatizer
Comparative examples 1-5, example 3 formulation "Deminshu
1.00g, Xin Min Shu
1000.20g, skin caring and refreshing
16092.00 g 'Demin Shu' instead
3g, Xin Min Shu
1000.20g, skin caring and refreshing
16090 g "; the rest is equivalent to example 3. .
The soothing skin care emulsions obtained in example 3 and comparative examples 1 to 5 were subjected to a histamine test as described in experiment 2 above; the results obtained are shown in Table 9 below.
TABLE 9 comparison of the application of the example 3 and the comparative examples 1 to 5 containing different concentrations of the phlegmatizer
Finally, it is also noted that the above-mentioned lists merely illustrate a few specific embodiments of the invention. It is obvious that the invention is not limited to the above embodiments, but that many variations are possible. All modifications which can be derived or suggested by a person skilled in the art from the disclosure of the present invention are to be considered within the scope of the invention.
Claims (3)
1. The allergy-relieving skin-care emulsion is characterized in that every 100g of the allergy-relieving skin-care emulsion comprises the following components in parts by weight:
2.6-2.8 g of polyglycerol-2 stearate, 5.9-6.0 g of jojoba oil, 3.4-3.6 g of plant squalane, 0.5-0.6 g of shea butter, 0.15g of vitamin E, 3.8-4.0 g of glycerol, 0.05g of sodium phytate, 0.03g of sodium hyaluronate, 1.8-2.0 g of trehalose and SolagumTM0.28-0.32 g of AX, 0.7-0.8 g of cetearyl olive oleate, 0.5g of jasmonate, 0.5g of 1, 2-hexanediol, 0.5g of water-soluble ceramide SK-INFLUX, 0.5-1.0 g of chlorpheniramine maleate, 0.1-0.2 g of chlorpheniramine maleate, 1.0-2.0 g of perhexiline and 0.05g of rose essence; the balance being deionized water.
2. The soothing skin care emulsion according to claim 1, wherein each 100g of the soothing skin care emulsion comprises the following formula by weight:
2.7g of polyglycerol-2 stearate, 6.0g of jojoba oil, 3.5g of plant squalane, 0.6g of shea butter, 0.15g of vitamin E, 4.0g of glycerol, 0.05g of sodium phytate, 0.03g of sodium hyaluronate, 2.0g of trehalose, and SolagumTMAX 0.3g, cetearyl olive oleate 0.8g, menthone 0.5g, 1, 2-hexanediol 0.5g, water-soluble ceramide SK-INFLUX 0.5g, DEMINGSHU
1.0g, Xin Min Shu
1000.2 g, skin caring and refreshing
16092.0 g, rose essence 0.05 g; the balance being deionized water.
3. A process for the preparation of a soothing skin care emulsion according to claim 1 or 2, characterized in that it comprises the following steps:
1) heating polyglycerol-2 stearate, jojoba oil, plant squalane, shea butter and vitamin E to 80 +/-5 ℃ under stirring, and keeping the temperature for 5-10 min to obtain an oil phase raw material;
2) mixing glycerol, sodium phytate, sodium hyaluronate, trehalose, and SolagumTMHeating AX, cetearyl olive oleate and deionized water to 80 +/-5 ℃ and keeping the temperature for 5-10 min; homogenizing for 30-40 s at a rotation speed of 7.5-8.0 krpm under a heat preservation condition; obtaining water phase raw materials;
3) pouring the water phase raw material in the heat preservation state obtained in the step 2) into the oil phase raw material in the heat preservation state obtained in the step 1), and homogenizing at 80 +/-5 ℃ at the rotating speed of 7.2-7.8 krpm for 8-10 min;
4) stirring the product obtained in the step 3) at the rotating speed of 250-280 rpm under the condition of stopping heating, adding the jasmone when the temperature is reduced to 60 +/-2 ℃, and adding the 1, 2-hexanediol and the water-soluble ceramide SK-INFLUX when the temperature is continuously reduced to 45 +/-2 ℃;
5) adding chlorphenamine maleate into the product obtained in the step 4)
Medicine for treating allergy
100, skin care and joyful
1609, flos Rosae Rugosae essence; continuously mechanically stirring at the rotating speed of 250-280 rpm until the temperature is cooled to room temperature。
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| CN108904384A (en) * | 2018-08-15 | 2018-11-30 | 广东丸美生物技术股份有限公司 | Skin matrix, preparation method and application and cosmetics |
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| CN110283336A (en) * | 2019-07-01 | 2019-09-27 | 广州大学 | A kind of preparation and application of the Organosilicon wax lotion for moisturizing cosmetic |
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| CN111249209B (en) * | 2020-03-30 | 2022-03-11 | 广东芭薇生物科技股份有限公司 | Moisturizing repair cream and preparation method thereof |
| FR3114024B1 (en) * | 2020-09-11 | 2022-09-09 | Fabre Pierre Dermo Cosmetique | New emulsion that mimics the skin |
| CN114224786A (en) * | 2021-12-14 | 2022-03-25 | 上海家化联合股份有限公司 | Composition comprising ceramide and uses thereof |
| CN114712276A (en) * | 2022-02-17 | 2022-07-08 | 诺德溯源(广州)生物科技有限公司 | Composition for relieving and improving skin state and skin care product |
| CN114869798B (en) * | 2022-05-17 | 2023-11-21 | 广东丸美生物技术股份有限公司 | Antiallergic formula with high retinol content, high retinol content cosmetic Huang Chunhua and preparation method thereof |
| CN115919706A (en) * | 2023-03-06 | 2023-04-07 | 天津郁美净集团有限公司 | Skin care product for improving skin irritation and tolerance and preparation method thereof |
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