CN107373088A - A kind of plant essential oil composition for substituting pig starter feed antibiotic and preparation method and application - Google Patents
A kind of plant essential oil composition for substituting pig starter feed antibiotic and preparation method and application Download PDFInfo
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- CN107373088A CN107373088A CN201710741776.2A CN201710741776A CN107373088A CN 107373088 A CN107373088 A CN 107373088A CN 201710741776 A CN201710741776 A CN 201710741776A CN 107373088 A CN107373088 A CN 107373088A
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- 239000000203 mixture Substances 0.000 title claims abstract description 99
- 230000003115 biocidal effect Effects 0.000 title claims abstract description 38
- 239000007858 starting material Substances 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title claims abstract description 20
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- INVGWHRKADIJHF-UHFFFAOYSA-N Sanguinarin Chemical compound C1=C2OCOC2=CC2=C3[N+](C)=CC4=C(OCO5)C5=CC=C4C3=CC=C21 INVGWHRKADIJHF-UHFFFAOYSA-N 0.000 claims abstract description 42
- 239000003921 oil Substances 0.000 claims abstract description 35
- WBYWAXJHAXSJNI-VOTSOKGWSA-M .beta-Phenylacrylic acid Natural products [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 claims abstract description 32
- WBYWAXJHAXSJNI-SREVYHEPSA-N Cinnamic acid Chemical compound OC(=O)\C=C/C1=CC=CC=C1 WBYWAXJHAXSJNI-SREVYHEPSA-N 0.000 claims abstract description 32
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- GOLXNESZZPUPJE-UHFFFAOYSA-N spiromesifen Chemical compound CC1=CC(C)=CC(C)=C1C(C(O1)=O)=C(OC(=O)CC(C)(C)C)C11CCCC1 GOLXNESZZPUPJE-UHFFFAOYSA-N 0.000 description 1
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- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 description 1
- MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/111—Aromatic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Birds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Feed For Specific Animals (AREA)
- Fodder In General (AREA)
Abstract
The present invention relates to a kind of plant essential oil composition for substituting pig starter feed antibiotic and preparation method and application, belong to field of fodder.The plant essential oil composition of above-mentioned replacement pig starter feed antibiotic includes cinnamic acid, origanum oil, lemongrass phenol, sanguinarine, citral, menthones, yellow artemone and eucalyptus oil.Said components are safe and non-toxic, have preferable antibacterial and antiviral functions, can lift piglet feed intake.The preparation method of plant essential oil composition is that the composition of above-mentioned each plant essential oil composition is mixed by proportioning, is then embedded, the method is simple and quick, can be well mixed each composition, avoid essential oil from volatilizing, and covers the penetrating odor of essential oil.It is applied to prepare in weanling pig feed using above-mentioned plant essential oil composition as feed addictive, the weanling pig feed of gained can significantly improve the daily ingestion amount of weanling pig, reduce harmful microbe content in feedstuff-meat ratio and intestine of young pigs, and not cause drug resistance and internal the problem of remaining.
Description
Technical field
The present invention relates to field of fodder, and more particularly to it is a kind of substitute pig starter feed antibiotic plant essential oil composition and
Its preparation method and application.
Background technology
The nearly more than ten years are also spread rapidly, caused to aquaculture industry of China with the rapid development of aquaculture industry of China, animal epidemic
Huge damage, antibiotic play positive effect in the preventing and treating of epidemic disease, however, long-term use of antibiotic, can cause animal
Internal pathogenic microorganisms drug resistance is continuously increased, while a large amount of uses of antibiotic, causes antibiotic in livestock products largely to remain,
Serious harm is constituted to the health of the mankind, the cry of limitation cultivating link antibiotic usage grows to even greater heights.European Union in
Forbid adding antibiotic in feed from January, 2006, nonreactive of carrying out in an all-round way cultivation.The Ministry of Agriculture of China provides sulfuric acid Bacillus adhaerens
The medicines such as element, chloramphenicol, vancomycin, olaquindox disable (partly disabling in growth promotion), make so as to pull open limitation antibiotic
Prelude, nonreactive cultivation has been trend of the times.
Therefore, the research of the antibiotic substitute in feed is extremely urgent in this day and age.
The content of the invention
An object of the present invention is to provide a kind of plant essential oil composition for substituting pig starter feed antibiotic, the plant
Component selected by essential oil composition derives from natural products, safe and non-toxic, has preferable antibacterial and antiviral functions, can be lifted
Piglet feed intake.
The second object of the present invention is to provide a kind of preparation method of above-mentioned plant essential oil composition, and the method is simply fast
Speed, it can be well mixed each composition, avoid essential oil from volatilizing, cover the penetrating odor of essential oil.
The third object of the present invention is to provide a kind of application of above-mentioned plant essential oil composition, added as feed
Agent is applied to prepare in weanling pig feed, and the weanling pig feed of gained can significantly improve the daily ingestion amount of weanling pig, drop
Harmful microbe content in low feedstuff-meat ratio and intestine of young pigs, and drug resistance and internal the problem of remaining are not caused.
The present invention is solved its technical problem and realized using following technical scheme：
The present invention proposes a kind of plant essential oil composition for substituting pig starter feed antibiotic, and the plant essential oil composition includes
The cinnamic acid of 10-20 parts by weight, the origanum oil of 10-20 parts by weight, the lemongrass phenol of 5-10 parts by weight, the red root of 5-10 parts by weight
Alkali, the citral of 5-15 parts by weight, the menthones of 10-15 parts by weight, 5-10 parts by weight yellow artemone and 5-10 parts by weight eucalyptus
Leaf oil.
The present invention also proposes a kind of preparation method of above-mentioned plant essential oil composition, comprises the following steps：By above-mentioned replacement
The proportioning of the plant essential oil composition of pig starter feed antibiotic, mixing cinnamic acid, origanum oil, lemongrass phenol, sanguinarine, citral,
Menthones, yellow artemone and eucalyptus oil, obtain essential oil thing, are then embedded.
The present invention also propose above-mentioned plant essential oil composition as feed addictive in weanling pig feed is prepared answering
With.
Plant essential oil composition of replacement pig starter feed antibiotic that present pre-ferred embodiments provide and preparation method thereof
Beneficial effect with application is：
It is certain by the way that cinnamic acid, origanum oil, lemongrass phenol, sanguinarine, citral, menthones, yellow artemone and eucalyptus oil are pressed
Ratio coordinates, and can start with terms of different sterilization and anti-inflammatory, the pathogen for causing intestine of young pigs disease is effectively pressed down
System, and reach synergistic function.Above-mentioned each component derives from natural products, safe and non-toxic.
Embedded after above-mentioned each essential oil component is mixed, thus the plant essential oil composition of gained has preferable antibacterial
And antiviral functions, piglet feed intake can be lifted.It also, above-mentioned preparation method is simple and quick, can be well mixed each composition,
Avoid essential oil from volatilizing, cover the penetrating odor of essential oil.
It is applied to the preparation of weanling pig feed using above-mentioned plant essential oil composition as feed addictive, preparation can be passed through
Obtained by weanling pig feed improve the daily ingestion amount of weanling pig, reduce harmful microbe in feedstuff-meat ratio and intestine of young pigs
Content, and drug resistance and internal the problem of remaining are not caused.
Embodiment
, below will be in the embodiment of the present invention to make the purpose, technical scheme and advantage of the embodiment of the present invention clearer
Technical scheme be clearly and completely described.Unreceipted actual conditions person, builds according to normal condition or manufacturer in embodiment
The condition of view is carried out.Agents useful for same or the unreceipted production firm person of instrument, it is the conventional production that can be obtained by commercially available purchase
Product.
Below to plant essential oil composition and preparation method thereof of the replacement pig starter feed antibiotic of the embodiment of the present invention with
Using being specifically described.
The plant essential oil composition for the replacement pig starter feed antibiotic that the embodiment of the present invention is provided, suitable for weanling pig
In feed.Because weanling pig easily suffers from intestines problem, and cause the Pathogen category of intestine of young pigs disease more, such as leather is blue
Family name's positive bacteria, Gram-negative bacteria, virus, coccidia etc..The embodiment of the present invention mainly with suppress Escherichia coli, salmonella and
C.perfringens is starting point, to reduce harmful microbe content and illness rate in intestine of young pigs, improves feed intake, and then
Improve the growth performance of weanling pig.
Optionally, the plant essential oil composition of above-mentioned replacement pig starter feed antibiotic can for example include 10-20 weights
Measure the cinnamic acid of part, the origanum oil of 10-20 parts by weight, the lemongrass phenol of 5-10 parts by weight, the sanguinarine of 5-10 parts by weight, 5-15 weights
Measure the citral of part, the menthones of 10-15 parts by weight, 5-10 parts by weight yellow artemone and 5-10 parts by weight eucalyptus oil.
Further, above-mentioned plant essential oil composition may include the cinnamic acid of 12-18 parts by weight, the ox of 12-18 parts by weight
To oil, the lemongrass phenol of 6-9 parts by weight, the sanguinarine of 6-9 parts by weight, the citral of 7-13 parts by weight, 11-14 parts by weight peppermint
Ketone, 6-9 parts by weight yellow artemone and 6-9 parts by weight eucalyptus oil.
Further, the cinnamic acid of 14-16 parts by weight, the origanum oil of 14-16 parts by weight, 7-8 weight can also be included
The lemongrass phenol of part, the sanguinarine of 7-8 parts by weight, the citral of 9-11 parts by weight, the menthones of 12-13 parts by weight, 7-8 parts by weight
Yellow artemone and 7-8 parts by weight eucalyptus oil.
More preferably, the cinnamic acid of the plant essential oil composition in the embodiment of the present invention including 15 parts by weight, 15 parts by weight
Origanum oil, the lemongrass phenol of 7.5 parts by weight, the sanguinarine of 7.5 parts by weight, the citral of 10 parts by weight, the peppermint of 12.5 parts by weight
The eucalyptus oil of ketone, the yellow artemone of 7.5 parts by weight and 7.5 parts by weight.The plant essential oil composition as obtained by this more excellent proportions
Each composition can largely play respective effect, and synergistic action effect is preferable.
Wherein, cinnamic acid is aldehydes organic compound, has broad-spectrum antibacterial effect, by destroying the cell membrane of bacterium, makes
Medicine is penetrated into bacterial cell, is destroyed organelle and is played sterilization and bacteriostasis effect, can especially suppress the grams such as Escherichia coli
Negative bacterium.Using cinnamic acid as one of composition of plant essential oil composition in the present embodiment, can more other plants essential oils have more
The effect of excellent regulation feed fragrance, lasting lasting, so as to lure livestock and poultry to feed.
In addition, feed cinnamic acid, it is possible to increase the main component (nitrogen) of animal muscle cell is synthesized in feed in animal
The internal amount of storing, improve animal meat quality quality.Also, the more other plant components of cinnamic acid have the effect of safer noresidue
Fruit, even if dosage in 25-200ppm scopes, will not also damage the intestinal villus of livestock and poultry.After feeding 24h, have 90% cinnamic acid with
Homaluria, 5% discharges with excrement, and remaining 5% can be broken down into nutriment, therefore, without any harmful in livestock and poultry body
Material residual.
Origanum oil has safe and efficient, green and the characteristics of without incompatibility.Compared to other chemical combination containing phenols
The essential oil of thing, origanum oil contain higher carvacrol, Thymol, a terpinenes and cymene simultaneously.Wherein, carvacrol and
Thymol can be such that necrosis is organized in enteral chamber and come off, accelerate to the active effect of intestinal mucosa maturation chamber epithelial cell
The turnover rate of the ripe chamber epithelial cell on intestinal villus surface, so as to reduce pathogenic infection epithelial cell, improve nutrient absorption energy
Power.
One of composition as plant essential oil composition, can be by destroying the penetrating of pathogenic microorganism biomembrane
Property, cellular content is overflowed, causes the interior environment of pathogenic microorganism unbalance, so as to play bactericidal action.Secondly, origanum oil with
Cinnamic acid can effectively cooperate with suppression to kill deleterious pathogens, protection intestinal microecology balance, prevent abdomen by the different modes of action
Rush down, reduce intestines problem, so as to promote piglet to grow.
What deserves to be explained is prior art is usual only individually by Thymol pure material and other essences in feed addictive
Oil collocation is used, but origanum oil and cinnamic acid are used cooperatively the rear fungistatic effect phase risen by its effect compared with the embodiment of the present invention
It is poor less, and the embodiment of the present invention origanum oil and cinnamic acid are used cooperatively after the effect that is risen to improving weaned piglets
It is significantly superior.
Lemongrass phenol is by the aldehydes matter essential oil that is extracted in lemongrass.It can cooperate with the cell membrane of cinnamic acid destruction bacterium,
The bactericidal effect of plant essential oil composition is improved, promotes weanling pig feeding, improves feed intake.
The bacteriostasis of sanguinarine is generally used for treating fish disease, especially for caused by the fungies such as mould and yeast
Disease.Because fungi and bacterium have larger difference in terms of structure and characteristic, therefore it is directly used in bacterial disease
The effect that rises is simultaneously bad.And it is used for the son that weans as one of composition of plant essential oil composition in the embodiment of the present invention
Pig, on the one hand by the synergy with cinnamic acid, origanum oil and lemongrass phenol, excite its to Escherichia coli, salmonella and
The inhibition of bacillus subtilis, on the other hand by using its antiinflammatory action, mitigate weanling pig body
Inflammatory reaction, so as to further strengthen sterilizing ability possessed by plant essential oil composition.
Citral is generally used for aspergillus flavus resisting, and its mechanism is mainly by destroying cell membrane and cell membrane so as to aspergillus flavus
Play inhibitory action.And mainly influenceed harmful as one of composition of plant essential oil composition in the embodiment of the present invention
The energetic supersession of bacterium and reduction enzyme system, so as to pass through different effects from cinnamic acid, origanum oil, lemongrass phenol and sanguinarine
Mode plays preferable fungistatic effect to Escherichia coli, salmonella and C.perfringens from different perspectives, further adds
Sterilizing ability possessed by strong plant essential oil composition.In addition, in the embodiment of the present invention, the suppression that citral rises to coccidia is imitated
Fruit is also more notable.
Menthones can be in dissolution of bacteria cell space lipid, reduce the mobility of adipose membrane, reduce bloody flux.Yellow artemone is
Ketone essential oil obtained by extraction in yellow wormwood artemisia, it can destroy bacterial cell membrane function, cause bacterial components to outflow and cause death.
Eucalyptus oil similarly has the bactericidal action of more wide spectrum, is mainly used in suppressing easily to draw in embodiments of the present invention
The breeding of the ill C.perfringens of weanling pig is played, meanwhile, reduce the generation of weanling pig breathing problem.
From the above, by by cinnamic acid, origanum oil, lemongrass phenol, sanguinarine, citral, peppermint in the embodiment of the present invention
Ketone, yellow artemone and eucalyptus oil coordinate by a certain percentage, can start with terms of different sterilization and anti-inflammatory, to causing intestine of young pigs
The pathogen of disease is effectively suppressed, and reaches synergistic function.
Further, the plant essential oil composition of above-mentioned replacement pig starter feed antibiotic can also include 5-45 parts by weight
Carrier.Further, carrier can be 10-40 parts by weight；Further, carrier can be 20-30 parts by weight；More preferably,
Carrier is 25 parts by weight.What deserves to be explained is by the derived essential oil in carrier and plant essential oil composition under more excellent proportioning
Mixing, more other proportioning combinations can more meet embedding and require, avoid causing plant essential oil composition institute after embedding
The sterilizing ability having declines.
Optionally, above-mentioned carrier can include corn flour and dregs of beans, and the weight ratio of the two is followed successively by 5-10：1.Selection
Two kinds of carrier mass can not only enrich the nutriment of plant essential oil composition, and can also make the equal energy of different derived essential oils
It is sufficiently mixed.
Further, the preparation method of above-mentioned plant essential oil composition can directly mix according to proportioning and substitute pig starter feed
The plant essential oil composition of antibiotic, essential oil thing is obtained, is then embedded.Specifically, first by proportioning mixing cinnamic acid,
Origanum oil, lemongrass phenol, sanguinarine, citral, menthones, yellow artemone and eucalyptus oil, obtain essential oil thing.Then above-mentioned essence is embedded again
Oily thing.
When containing carrier in plant essential oil composition, then the essential oil thing for mixing gained can be mixed with carrier by proportioning,
Mixture is obtained, is then embedded again.
Embedding may comprise steps of：It will treat that embedded object and wall material are by weight 2-4：1 mixing, spray drying.Its
In, wall material can be 4-5 including weight ratio：2-4 soybean protein isolate and Arabic gum.It is worth noting that, when plant essence
When carrier is free of in fluid composition, it is essential oil thing to treat embedded object；When containing carrier in plant essential oil composition, treat that embedded object is
The mixture of gained after essential oil thing mixes with carrier.
, can more other coating materials as embedding wall material after soybean protein isolate and Arabic gum are mixed by said ratio
It is more preferable to the mixture embedding effect in the embodiment of the present invention, the activity of mixture will not be had undesirable effect, and more hold
Easily digested and assimilated by piglet.
It is preferred that the EAT of above-mentioned spray drying is 180-190 DEG C, charging rate 54-58mL/min.Generally,
The EAT of spray drying is no more than 150 DEG C, in view of charging rate is very fast in the embodiment of the present invention, air intake is improved so as to relative
Temperature, the two cooperation can reach good drying effect.
Hold, embedding process is in view of above-mentioned plants essential oil is readily volatilized and Activities of Some Plants essential oil group in the embodiment of the present invention
Point with stronger penetrating odor and special setting, on the one hand essential oil can be avoided to volatilize by embedding, cause activity into
Divide and reduce or lose, on the other hand can also cover penetrating odor, improve weanling pig food-intake.
Further, it is disconnected in preparation as feed addictive to additionally provide above-mentioned plant essential oil composition for the embodiment of the present invention
Application in milk pig starter feed.Optionally, the above-mentioned plants essential oils of 100-300mg can be added in every kilogram of weanling pig feed
Composition, it is preferable that addition 200mg., can be obvious by adding above-mentioned plant essential oil composition in weanling pig feed
Improve the daily ingestion amount of weanling pig, reduce harmful microbe content in feedstuff-meat ratio and intestine of young pigs, and do not cause resistance
Property and in vivo residual the problem of.
What deserves to be explained is the plant essential oil composition contained substance of pig starter feed antibiotic is substituted in the embodiment of the present invention
It is not limited in the above-mentioned material being previously mentioned, the producer can also be according to the different demands and upgrowth situation of piglet in pig starter feed
Add other materials.
The feature and performance of the present invention are described in further detail with reference to embodiments.
Embodiment 1
By the cinnamic acid of 10 parts by weight, the origanum oil of 10 parts by weight, the lemongrass phenol of 5 parts by weight, the sanguinarine of 5 parts by weight, 5
The eucalyptus oil mixing of the citral of parts by weight, the menthones of 10 parts by weight, the yellow artemone of 5 parts by weight and 5 parts by weight, obtains essential oil
Thing.
It is 2 by weight by essential oil thing and wall material:1 mixing, then in EAT be 180 DEG C, charging rate 54mL/
It is spray-dried under conditions of min.
Wherein, wall material contains weight ratio for 4:2 soybean protein isolate and Arabic gum.
Embodiment 2
By the cinnamic acid of 10 parts by weight, the origanum oil of 10 parts by weight, the lemongrass phenol of 5 parts by weight, the sanguinarine of 5 parts by weight, 5
The eucalyptus oil mixing of the citral of parts by weight, the menthones of 10 parts by weight, the yellow artemone of 5 parts by weight and 5 parts by weight, obtains essential oil
Thing.
Above-mentioned essential oil thing is mixed with the carrier of 5 parts by weight, obtains mixture.It is 2 by weight by mixture and wall material:
1 mixing, is then spray-dried under conditions of EAT is 180 DEG C, charging rate is 54mL/min.
Wherein, carrier contains weight ratio for 5:1 corn flour and dregs of beans, wall material contain weight ratio for 4:2 soybean separation
Albumen and Arabic gum.
Embodiment 3
By the cinnamic acid of 20 parts by weight, the origanum oil of 20 parts by weight, the lemongrass phenol of 10 parts by weight, 10 parts by weight red root
The eucalyptus oil mixing of alkali, the citral of 15 parts by weight, the menthones of 15 parts by weight, the yellow artemone of 10 parts by weight and 10 parts by weight,
Obtain essential oil thing.
Above-mentioned essential oil thing is mixed with the carrier of 45 parts by weight, obtains mixture.It is by weight with wall material by mixture
4:1 mixing, is then spray-dried under conditions of EAT is 190 DEG C, charging rate is 58mL/min.
Wherein, carrier contains weight ratio for 10:1 corn flour and dregs of beans, wall material contain weight ratio for 5:4 soybean separation
Albumen and Arabic gum.
Embodiment 4
By the cinnamic acid of 12 parts by weight, the origanum oil of 18 parts by weight, the lemongrass phenol of 6 parts by weight, the sanguinarine of 9 parts by weight, 7
The eucalyptus oil mixing of the citral of parts by weight, the menthones of 14 parts by weight, the yellow artemone of 6 parts by weight and 9 parts by weight, obtains essential oil
Thing.
Above-mentioned essential oil thing is mixed with the carrier of 10 parts by weight, obtains mixture.It is by weight with wall material by mixture
3:1 mixing, is then spray-dried under conditions of EAT is 185 DEG C, charging rate is 56mL/min.
Wherein, carrier contains weight ratio for 7.5:1 corn flour and dregs of beans, wall material contain weight ratio for 4.5:3 soybean
Protein isolate and Arabic gum.
Embodiment 5
By the cinnamic acid of 18 parts by weight, the origanum oil of 12 parts by weight, the lemongrass phenol of 9 parts by weight, 6 parts by weight sanguinarine,
The eucalyptus oil mixing of the citral of 13 parts by weight, the menthones of 11 parts by weight, the yellow artemone of 9 parts by weight and 6 parts by weight, obtains essence
Oily thing.
It is 2.5 by weight by above-mentioned essential oil thing and wall material:1 mixing, then it is 182.5 DEG C, feeds speed in EAT
Spend to be spray-dried under conditions of 55mL/min.
Wherein, carrier contains weight ratio for 6:1 corn flour and dregs of beans, wall material contain weight ratio for 4.2:2.5 soybean
Protein isolate and Arabic gum.
Embodiment 6
By the cinnamic acid of 14 parts by weight, the origanum oil of 14 parts by weight, the lemongrass phenol of 7 parts by weight, 7 parts by weight sanguinarine,
The eucalyptus oil mixing of the citral of 11 parts by weight, the menthones of 13 parts by weight, the yellow artemone of 8 parts by weight and 8 parts by weight, obtains essence
Oily thing.
Above-mentioned essential oil thing is mixed with the carrier of 20 parts by weight, obtains mixture.It is by weight with wall material by mixture
3.5:1 mixing, is then spray-dried under conditions of EAT is 187.5 DEG C, charging rate is 57mL/min.
Wherein, carrier contains weight ratio for 9:1 corn flour and dregs of beans, wall material contain weight ratio for 4.7:3.5 soybean
Protein isolate and Arabic gum.
Embodiment 7
By the cinnamic acid of 16 parts by weight, the origanum oil of 16 parts by weight, the lemongrass phenol of 8 parts by weight, the sanguinarine of 8 parts by weight, 9
The eucalyptus oil mixing of the citral of parts by weight, the menthones of 12 parts by weight, the yellow artemone of 7 parts by weight and 7 parts by weight, obtains essential oil
Thing.
Above-mentioned essential oil thing is mixed with the carrier of 30 parts by weight, obtains mixture.It is by weight with wall material by mixture
3:1 mixing, is then spray-dried under conditions of EAT is 185 DEG C, charging rate is 56mL/min.
Wherein, carrier contains weight ratio for 7:1 corn flour and dregs of beans, wall material contain weight ratio for 4.5:3 soybean point
From albumen and Arabic gum.
Embodiment 8
By the cinnamic acid of 15 parts by weight, the origanum oil of 15 parts by weight, the lemongrass phenol of 7.5 parts by weight, 7.5 parts by weight red root
Alkali, the citral of 10 parts by weight, the menthones of 12.5 parts by weight, the eucalyptus oil of the yellow artemone of 7.5 parts by weight and 7.5 parts by weight mix
Close, obtain essential oil thing.
Above-mentioned essential oil thing is mixed with the carrier of 25 parts by weight, obtains mixture.It is by weight with wall material by mixture
3:1 mixing, is then spray-dried under conditions of EAT is 185 DEG C, charging rate is 56mL/min.
Wherein, carrier contains weight ratio for 8:1 corn flour and dregs of beans, wall material contain weight ratio for 4.5:3 soybean point
From albumen and Arabic gum.
Embodiment 9
Any plant essential oil composition in 100mg embodiments 1-8 is added into 1kg weanling pig feeds.
Embodiment 10
Any plant essential oil composition in 300mg embodiments 1-8 is added into 1kg weanling pig feeds.
Embodiment 11
Any plant essential oil composition in 200mg embodiments 1-8 is added into 1kg weanling pig feeds.
Test example 1
Repeat to implement above-described embodiment 1-8, obtain enough plant essential oil compositions.It is 24 ± 2 to select 500 ages in days
It health and body weight similar in weanling pig (kind be Duroc × length in vain × great Bai), be randomly divided into 2 groups of control groups and 8
Group test group.
Wherein, control group 1 feeds basal diet, without antibiotic and plants essential oil；Control group 2 is antibiotic group, that is, is existed
On the basis of basal diet, enramycin 10mg, olaquindox 100mg and kitasamycin 75mg are added in every kilogram of feed.Experiment
Group 1-8 on the basis of basal diet, adds the plants essential oil combination obtained by 200mg embodiments 1-8 respectively in every kilogram of feed
Thing, test period are 30 days.
The feed intake of weanling pig in test period internal reference group and test group is counted and recorded, record is young respectively
Pig original body mass and whole opisthosoma weight, calculate average daily gain, average daily gain and feedstuff-meat ratio.To test period internal reference group and
The diarrhoea situation of weanling pig and the death rate are recorded and counted in test group.Take weanling pig in control group and test group
Excrement simultaneously determines microbial biomass contained therein.Its result is as shown in table 1.
Wherein, content of microorganisms assay method is as follows：10g excrement sample is taken to be added in the sterile triangular flask with bead
90mL sterile salines, fully vibration, as 10-1Times dilution.The above-mentioned dilutions of 1mL are drawn in filling 9mL axenic purifications
10 are carried out in the test tube of water-2Dilute again, shaken well, and carry out 10 successively-3-10-9Dilute again.0.2mL is taken respectively to dilute respectively
Liquid, wherein 0.1mL are coated on Yihong-methylene blue culture medium plate, and another 0.1mL is coated on MRS culture medium plates, in 37 DEG C of condition
Lower culture 48h, carry out bacterium colony counting.It is final using the average for cultivating E. coli clones quantity in latter two culture medium plate
The result of clump count.
Influence of the 1 different plant essential oil compositions of table to weanling pig
Wherein, daily gain and the unit of daily ingestion amount are g, and the unit of diarrhea rate and the death rate is %, the unit of clump count
For logCFU/g.
As can be seen from Table 1, the average daily gain of weanling pig corresponding to control group 2 and test group 1-8 and average adopt day
Appetite is higher compared with control group 1, and feedstuff-meat ratio, diarrhea rate, the death rate and clump count are lower compared with control group 1.Illustrate to contain by feeding
The feed for having embodiment 1-8 plant essential oil composition can effectively improve the daily gain and daily ingestion amount of weanling pig, reduce
The content of harmful microorganism (Escherichia coli) in the feedstuff-meat ratio and intestine of young pigs of piglet, so as to reduce the diarrhea rate of piglet and dead
Die rate.Test group 1-8 action effect is overall more preferable compared with control group 2, and the plant essential oil composition contained by test group 1-8 is more right
There is the problem of safe and non-toxic, not produce drug resistance and remain in vivo according to the antibiotic contained by group 2.In addition, pass through contrast, examination
The salmonella tested in weanling pig excrement corresponding to group 1-8 and the content of C.perfringens are lower compared with control group 1.
Therefore, the composite plant essential oil feed addictive in the embodiment of the present invention can be replaced currently used antibiotic
For feeding weanling pig to improve its growth performance.
For test group 1-8, test group 2-8 compared with test group 1 in above-mentioned pilot project it is possessed better, say
Whether contain carrier in bright plant essential oil composition, there is one surely to influence the growth performance of weanling pig, do not contain containing carrier
Carrier is good.Test group 4-8 possessed better, test group 6-7 relatively experiments in above-mentioned pilot project compared with test group 2-3
Group 4-5 possessed by better, the best results that test group 8 has in all test groups, so as to illustrate test group 8 compared with
The proportioning of each essential oil is more preferably in other test groups.
Test example 2
By taking the plant essential oil composition of the gained of embodiment 8 as an example (namely test group 8 in test example 1), control group is set
3, control group 3 replaces origanum oil with Thymol pure material, according to daily gain of the method in test example 1 to weanling pig, day
Feed intake, feedstuff-meat ratio, diarrhea rate, the death rate and clump count are compared, and its result is as shown in table 2, control group 1 and right in table 2
It is consistent with the control group 1 in test example 1 and control group 2 according to group 2.
The influence of the control group of table 2 and test group to weanling pig
| Control group 1 | Control group 2 | Control group 3 | Test group 8 | |
| Daily gain | 500 | 505 | 535 | 613 |
| Daily ingestion amount | 850 | 852 | 874 | 920 |
| Feedstuff-meat ratio | 1.70 | 1.69 | 1.63 | 1.50 |
| Diarrhea rate | 12.6 | 9.7 | 4.9 | 3 |
| The death rate | 5 | 4 | 3 | 1 |
| Clump count | 6.24 | 5.51 | 2.47 | 2.45 |
Wherein, daily gain and the unit of daily ingestion amount are g, and the unit of diarrhea rate and the death rate is %, the unit of clump count
For logCFU/g.
As can be seen from Table 2, by the way that Thymol pure material is replaced into origanum oil, though the two fungistatic effect risen differs
Less, but in general, the feed that the feed after origanum oil does not replace is replaced by Thymol pure material to weanling pig
The positive effect that production performance rises is worse.Illustrate that other compositions contained in origanum oil in the embodiment of the present invention can be with Chinese cassia tree
The materials such as aldehyde act synergistically, and reach more excellent action effect.
In summary, component selected by the plant essential oil composition of present invention replacement pig starter feed antibiotic derives from naturally
Product, it is safe and non-toxic, there are preferable antibacterial and antiviral functions, piglet feed intake can be lifted.The plant essential oil composition
Preparation method is simple and quick, can be well mixed each composition, avoid essential oil from volatilizing, and covers the penetrating odor of essential oil.Will be above-mentioned
Plant essential oil composition is applied to prepare weanling pig feed as feed addictive, and obtained weanling pig feed significantly improves
The daily ingestion amount of weanling pig, reduce harmful microbe content in feedstuff-meat ratio and intestine of young pigs, and do not cause drug resistance and
In vivo the problem of residual.
Embodiments described above is part of the embodiment of the present invention, rather than whole embodiments.The reality of the present invention
The detailed description for applying example is not intended to limit the scope of claimed invention, but is merely representative of the selected implementation of the present invention
Example.Based on the embodiment in the present invention, what those of ordinary skill in the art were obtained under the premise of creative work is not made
Every other embodiment, belongs to the scope of protection of the invention.
Claims (10)
1. a kind of plant essential oil composition for substituting pig starter feed antibiotic, it is characterised in that include the Chinese cassia tree of 10-20 parts by weight
Aldehyde, the origanum oil of 10-20 parts by weight, the lemongrass phenol of 5-10 parts by weight, the sanguinarine of 5-10 parts by weight, the lemon of 5-15 parts by weight
Aldehyde, the menthones of 10-15 parts by weight, 5-10 parts by weight yellow artemone and 5-10 parts by weight eucalyptus oil.
2. the plant essential oil composition according to claim 1 for substituting pig starter feed antibiotic, it is characterised in that including
The cinnamic acid of 12-18 parts by weight, the origanum oil of 12-18 parts by weight, the lemongrass phenol of 6-9 parts by weight, 6-9 weight
Part the sanguinarine, the citral of 7-13 parts by weight, the menthones of 11-14 parts by weight, 6-9 parts by weight it is described
The eucalyptus oil of yellow artemone and 6-9 parts by weight.
3. the plant essential oil composition according to claim 2 for substituting pig starter feed antibiotic, it is characterised in that including 15
The cinnamic acid of parts by weight, the origanum oil of 15 parts by weight, the lemongrass phenol of 7.5 parts by weight, 7.5 parts by weight it is described
Sanguinarine, the citral of 10 parts by weight, the menthones of 12.5 parts by weight, the yellow artemone and 7.5 of 7.5 parts by weight
The eucalyptus oil of parts by weight.
4. the plant essential oil composition of the replacement pig starter feed antibiotic according to claim any one of 1-3, its feature exist
In including the carrier of 5-45 parts by weight, the carrier is 5-10 including weight ratio：1 corn flour and dregs of beans.
5. a kind of preparation method for the plant essential oil composition for substituting pig starter feed antibiotic, it is characterised in that including following step
Suddenly：As the proportioning of the plant essential oil composition of the replacement pig starter feed antibiotic as described in claim any one of 1-3, institute is mixed
State cinnamic acid, the origanum oil, the lemongrass phenol, the sanguinarine, the citral, the menthones, the yellow artemone and
The eucalyptus oil, essential oil thing is obtained, is then embedded.
6. preparation method according to claim 5, it is characterised in that the plants essential oil for substituting pig starter feed antibiotic
Composition also includes the carrier of 5-45 parts by weight, and the carrier is 5-10 including weight ratio：1 corn flour and dregs of beans, during preparation,
The essential oil thing is mixed with the corn flour and the dregs of beans, mixture is obtained, is then embedded again.
7. preparation method according to claim 6, it is characterised in that comprise the following steps：By the mixture with
Wall material is by weight 2-4：1 mixing, spray drying；The wall material is 4-5 including weight ratio：2-4 soybean protein isolate and
Arabic gum.
8. preparation method according to claim 7, it is characterised in that the EAT of spray drying be 180-190 DEG C or
Charging rate is 54-58mL/min.
9. the plant essential oil composition of the replacement pig starter feed antibiotic as described in claim any one of 1-4 adds as feed
Application of the agent in weanling pig feed is prepared.
10. the plant essential oil composition according to claim 9 for substituting pig starter feed antibiotic exists as feed addictive
Prepare the application in weanling pig feed, it is characterised in that replacement described in 100-300mg is added in every kilogram of weanling pig feed
The plant essential oil composition of pig starter feed antibiotic.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110201035A (en) * | 2019-06-21 | 2019-09-06 | 刘春海 | A kind of fowl plant essential oil composition and its preparation method and application |
| CN111084279A (en) * | 2019-12-31 | 2020-05-01 | 广东瑞生科技集团有限公司 | Novel feed additive and preparation method thereof |
| CN115316532A (en) * | 2022-08-08 | 2022-11-11 | 青岛农业大学 | Substitute of antibiotic growth promoter for fattening pig feed and application thereof |
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| CN103082093A (en) * | 2013-01-31 | 2013-05-08 | 武汉工业学院 | Coated natural plant essential oil feed additive and application thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110201035A (en) * | 2019-06-21 | 2019-09-06 | 刘春海 | A kind of fowl plant essential oil composition and its preparation method and application |
| CN110201035B (en) * | 2019-06-21 | 2021-08-24 | 辽宁菲迪饲料科技有限责任公司 | Plant essential oil composition for poultry and preparation method and application thereof |
| CN111084279A (en) * | 2019-12-31 | 2020-05-01 | 广东瑞生科技集团有限公司 | Novel feed additive and preparation method thereof |
| CN115316532A (en) * | 2022-08-08 | 2022-11-11 | 青岛农业大学 | Substitute of antibiotic growth promoter for fattening pig feed and application thereof |
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