CN107349382A - It is a kind of treat ankylosing spondylitis superintend and direct moxibustion powder and preparation method thereof - Google Patents
It is a kind of treat ankylosing spondylitis superintend and direct moxibustion powder and preparation method thereof Download PDFInfo
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- CN107349382A CN107349382A CN201610298067.7A CN201610298067A CN107349382A CN 107349382 A CN107349382 A CN 107349382A CN 201610298067 A CN201610298067 A CN 201610298067A CN 107349382 A CN107349382 A CN 107349382A
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Abstract
It is a kind of treat ankylosing spondylitis superintend and direct moxibustion powder and preparation method thereof, by being prepared below according to weight proportion Chinese medicine material and Western medicine raw material：Chinese medicine material:Pawpaw, caulis piperis futokadsurae, long-nosed pit viper, Polygonum multiflower knotweed, turmeric, sargentodoxa cuneata, lycopodium calvatum, clerodendron trichotomum, caulis sinomenii, smilax, bark of ash, levisticum, madder, giant knotweed, Ligusticum wallichii, bush, the red sage root, safflower, peach kernel, Asian puccoon, folium isatidis, airpotato yam, field pennycress, cymose buckwheat rhizome, centipede, hippocampus, rhizoma homalonemae, scorpio, the root of Chinese clematis, Morinda officinalis, cortex acanthopanacis, Ramulus Taxilli, reticulate millettia, rhizoma cibotii, pyrola, rhizoma Gastrodiae, Rhizoma Corydalis (processed with vinegar), frankincense, myrrh, Moschus, borneol, datura flower；Western medicine raw material：Thiamine Hydrochloride Tablets, vitamin B12 piece.This treatment medicinal powder is according to theory of traditional Chinese medical science, diagnosis and treatment based on an overall analysis of the illness and the patient's condition, the simultaneous cure rate made, can significantly improve patient of sample.
Description
Technical field
The present invention relates to a kind of medicinal powder prepared using Chinese herbal medicine as primary raw material, specifically it is a kind of treat ankylosing spondylitis superintend and direct moxibustion powder and preparation method thereof.
Background technology
Ankylosing spondylitis (AS) is that a kind of cause of disease is unknown, the systemic disease based on middle axis joint chronic inflammation.Mainly involve articulatio sacroiliaca, hip joint, articuli intervertebrales, costovertebral joint, it is the most common with Sacroiliac Joint Disorder, it there are about 1/3 surroundings thereof joint and inflammation occur, and eye, heart, lungs, nervous system and urinary system can be involved.Its main pathology is to change joint and periarticular tissue, the calcification of ligament, interverbebral disc, and rigid spine finally occurs.Thus ankylosing spondylitis is the disease that disability rate is high, has a strong impact on health of people.Ankylosing spondylitis belongs to the category of the traditional Chinese medical science " rheumatism " or " waist disease ", belongs to rheumatism category in doctor trained in Western medicine.This sick site of pathological change is mainly lumbosacral region and ridge, the closest with kidney and governor vessel relation.The kidney being the origin of congenital constitution, and main bone gives birth to marrow, and ridge is full of in kidney system, and the narrow ridge of governor vessel is full of in waist, and the sun of governor's the whole body is particularly close with kidney relation, therefore relevant with kidney qi deficiency governor vessel inanition more than this sick generation.In the case of healthy tendency virtual loss, chill it is puckery heat at the beginning of take advantage of a weak point, numbness resistance governor vessel, QI-blood circulation is not smooth, not general rule disease and cause low-back pain.This disease is occurred in adolescents in male, and patient is rare after 40 years old.Because the mechanism of this sick cause of disease, morbidity is still not clear, so lacking specificity therapeutic method.
At present, mainly there are physical exercise therapy, physiotherapy, medicine and surgical intervention etc..1. physical exercise therapy：Sports therapy is beneficial to various chronic diseases, even more important to AS.The physiological bending of backbone can be kept, prevents deformity；Normal respiratory function is maintained, bone density and intensity is kept, prevents osteoporosis and limbs disuse muscle atrophy etc., can specifically make following move.(1) deeply breathe：Every morning, work and rest time and the motion that all should routinely breathe deeply before sleeping, the mobility that thorax can be maintained maximum of deeply breathing, keep good respiratory function;(2) cervical vertebra moves：Incidence can make forward, backward, to the left, turn right, and end rotation motion, to keep the normal activity degree of cervical vertebra；(3) lumbar vertebrae moves:Every heaven-made waist movement, anteflexion, layback, lateral bending and left rotation and right rotation body, make lumbar spinal column keep normal mobility；(4) limb motion；Push-up, diagonal brace, lower limb anterior flexion and rear stretching, chest expanding exercise and swimming etc. can be made, swimming not only improves quadruped locomotion, contributes to increase PFT again and backbone is kept physiological camber, is the most suitable all-around exercises of AS.2. physical treatment：Physiotherapy is generally available thermotherapy, such as hot bath, basin bath or shower, mineral spring Hot Spring Bath etc., to increase local blood circulation, makes loosening all muscles, mitigates pain, be advantageous to joint motion, keep normal function, prevent deformity.3. drug therapy：Treatment AS medicine can be divided into three classes：1. symptom management is movable, the medicine of course advancement, such as salicylazosulfapyridine are influenceed, methotrexate (MTX), now newest also has " biological agent " benefit match spectrum-tnf antibody fusion protein evident in efficacy, suitable for the AS of state of an illness activity, with the arthritic AS and newly discovered AS in periphery；2. NSAIDs, suitable for night severe pain and stiff patient, it can be taken before sleeping；3. antalgesic and muscle relaxant such as pentazocine, strong pain pyridine Nefopam, are usually used in prolonged application non-steroid anti-inflammatory drug nonresponder.4. operative treatment:Serious backbone hunchback deformity can make corrective procedure after stable disease；Lumbar vertebrae deformity person is feasible, and the correction of Rachis trauma art is bow-backed；The rectifiable cervical vertebra severe deformities of the osteotomy of 7 chest of neck 1；The serious flexion deformity of hip joint, feasible full hip-joint conversion art or arthroplasty of hip, but effect is not ideal enough, it is postoperative easily tetanic again.The physical exercise therapy of prior art, physiotherapy method, the problem of long course for the treatment of, effect difference be present；And medicinal treatment, it is mostly oral western medicine, treatment cost height is present and has the problem of side effect：And there is the problem of patient suffering is big in operative treatment.
Superintend and direct moxibustion and be also known as long-snake moxibustion, be a kind of imposed on governor vessel every medicine or every ginger or the therapy of garlic moxibustion.It is on the backbone of human body to superintend and direct moxibustion（In the spinal column segment of governor vessel described in the traditional Chinese medical science）Impose a kind of characteristic external treatment of traditional Chinese medicine of indirect moxibustion, it is by improvement on the basis of the ancient therapy of the traditional Chinese medical science " paving moxibustion ", suitable for alleviating because of the pain caused by the arthralgias and soft tissue strain and contusion etc. such as the neck caused by chill, heresy are wet, shoulder, waist, leg, treatment is arrogated to oneself especially as the pain caused by ankylosing spondylitis.Its treatment method：The naked back of the body prostrate of patient is made on bed, taking governor vessel big vertebra to the backbone position of Yaoshu(Du 2).After routine disinfection ginger juice is smeared in therapentic part, sprinkled again on therapentic part and superintend and direct moxibustion powder, mulberry paper is covered thereon afterwards, then again in mulberry paper upper berth ginger mud such as scalariform, moxa cone finally is placed above in ginger mud, then light, ginger mud and Chinese mugwort ash are removed after continuous moxibustion treatment, then therapentic part wiped clean with damp and hot towel.Ankylosing spondylitis of the present invention superintends and directs moxibustion powder and coordinates all warps by exciting for the clinical symptoms of patients with ankylosing spondylitis, plays Yin Yang balancing, resists disease and evil, temperature compensation governor vessel, strengthens true strength, warm venting QI-blood, the effect of adjusting actual situation；Multi-medicament use in conjunction plays a part of analgesic, muscle-growing and detumescence, promoting blood circulation and removing blood stasis, dredging collateral, and can treat both principal and secondary aspect of disease, have no side effect, be cheap.
The content of the invention
It is an object of the invention to provide a kind of medicinal powder prepared using Chinese herbal medicine as primary raw material, specifically it is a kind of treat ankylosing spondylitis superintend and direct moxibustion powder and preparation method thereof.
To achieve the above object, the technical solution adopted by the present invention is：
It is a kind of treat ankylosing spondylitis superintend and direct moxibustion powder, it is characterized in that, be made up of the Chinese medicine material and Western medicine raw material of following weight proportion：
Chinese medicine material：Pawpaw 100g,Caulis piperis futokadsurae 150g,Long-nosed pit viper 100g,Polygonum multiflower knotweed 100g,Turmeric 100g,Sargentodoxa cuneata 120g,Frankincense 50g,Myrrh 50g,Lycopodium calvatum 100g,Clerodendron trichotomum 100g,Caulis sinomenii 100g,Smilax 100g,Bark of ash 100g,Levisticum 100g,Madder 50g,Giant knotweed 150g,Ligusticum wallichii 100g,Bush 50g,Red sage root 150g,Safflower 100g,Peach kernel 100g,Moschus 1g,Borneol 1.5g,Asian puccoon 100g,Folium isatidis 100g,Airpotato yam 50g,Field pennycress 100g,Cymose buckwheat rhizome 100g,Centipede 50g,Hippocampus 3 0g,Rhizoma homalonemae 50g,Scorpio 50g,Root of Chinese clematis 50g,Morinda officinalis 50g,Cortex acanthopanacis 150g,Ramulus Taxilli 100g,Reticulate millettia 150g,Rhizoma cibotii 150g,Pyrola 100g,Rhizoma Gastrodiae 50g,Rhizoma Corydalis (processed with vinegar) 50g,Datura flower 3g；
Western medicine raw material：Thiamine Hydrochloride Tablets（10mg/ pieces）10；Vitamin B12 piece（25ug/ pieces）40；
Above-mentioned raw materials medicine is prepared according to the following steps：
（1）By in above-mentioned Chinese medicine material：Pawpaw 100g,Caulis piperis futokadsurae 150g,Long-nosed pit viper 100g,Polygonum multiflower knotweed 100g,Turmeric 100g,Sargentodoxa cuneata 120g,Lycopodium calvatum 100g,Clerodendron trichotomum 100g,Caulis sinomenii 100g,Smilax 100g,Bark of ash 100g,Levisticum 100g,Madder 50g,Giant knotweed 150g,Ligusticum wallichii 100g,Bush 50g,Red sage root 150g,Safflower 100g,Peach kernel 100g,Asian puccoon 100g,Folium isatidis 100g,Airpotato yam 50g,Field pennycress 100g,Cymose buckwheat rhizome 100g,Centipede 50g,Hippocampus 3 0g,Rhizoma homalonemae 50g,Scorpio 50g,Root of Chinese clematis 50g,Morinda officinalis 50g,Cortex acanthopanacis 150g,Ramulus Taxilli 100g,Reticulate millettia 150g,Rhizoma cibotii 150g,Pyrola 100g,Rhizoma Gastrodiae 50g,Co-grinding is into fine powder after Rhizoma Corydalis (processed with vinegar) 50g is dried,Using being divided into 10 parts after ethylene oxide sterilizing,Plastic packaging is in standby in polybag；
（2）Frankincense 50g, myrrh 50g, Moschus 1g, borneol 1.5g, datura flower 3g are individually ground into fine powder, are well mixed, using being divided into 10 parts after ethylene oxide sterilizing, plastic packaging is in standby in polybag；
（3）Used time takes Thiamine Hydrochloride Tablets（10mg/ pieces）1, vitamin B12 piece（25ug/ pieces）4 are ground into fine powder and step（1）、（2）In standby medicinal powder it is each a well mixed, finally to superintend and direct moxibustion powder.
A kind of method for preparing ankylosing spondylitis and superintending and directing moxibustion powder, it is characterized in that：The bulk drug is prepared according to the following steps：
（1）By in above-mentioned Chinese medicine material：Pawpaw 100g,Caulis piperis futokadsurae 150g,Long-nosed pit viper 100g,Polygonum multiflower knotweed 100g,Turmeric 100g,Sargentodoxa cuneata 120g,Lycopodium calvatum 100g,Clerodendron trichotomum 100g,Caulis sinomenii 100g,Smilax 100g,Bark of ash 100g,Levisticum 100g,Madder 50g,Giant knotweed 150g,Ligusticum wallichii 100g,Bush 50g,Red sage root 150g,Safflower 100g,Peach kernel 100g,Asian puccoon 100g,Folium isatidis 100g,Airpotato yam 50g,Field pennycress 100g,Cymose buckwheat rhizome 100g,Centipede 50g,Hippocampus 3 0g,Rhizoma homalonemae 50g,Scorpio 50g,Root of Chinese clematis 50g,Morinda officinalis 50g,Cortex acanthopanacis 150g,Ramulus Taxilli 100g,Reticulate millettia 150g,Rhizoma cibotii 150g,Pyrola 100g,Rhizoma Gastrodiae 50g,Co-grinding is into fine powder after Rhizoma Corydalis (processed with vinegar) 50g is dried,Using being divided into 10 parts after ethylene oxide sterilizing,Plastic packaging is in standby in polybag；
（2）Frankincense 50g, myrrh 50g, Moschus 1g, borneol 1.5g, datura flower 3g are individually ground into fine powder, are well mixed, using being divided into 10 parts after ethylene oxide sterilizing, plastic packaging is in standby in polybag；
（3）Used time takes Thiamine Hydrochloride Tablets（10mg/ pieces）1, vitamin B12 piece（25ug/ pieces）4 are ground into fine powder and step（1）、（2）In standby medicinal powder it is each a well mixed, finally to superintend and direct moxibustion powder.
Beneficial effects of the present invention：
1. many medicine comprehensive improvements, treat both principal and secondary aspect of disease.Ankylosing spondylitis of the present invention superintends and directs moxibustion powder and coordinates all warps by exciting for the clinical symptoms of patients with ankylosing spondylitis, plays Yin Yang balancing, resists disease and evil, temperature compensation governor vessel, strengthens true strength, warm venting QI-blood, the effect of adjusting actual situation；Multi-medicament use in conjunction plays a part of analgesic, muscle-growing and detumescence, promoting blood circulation and removing blood stasis, dredging collateral, and can treat both principal and secondary aspect of disease, have no side effect, be cheap.
2. Chinese medicine coordinates Western medicine application, nerve fiber, the metabolism of muscle activity and function can be maintained normal, promote development and the maturation of red blood cell, human body hematopoietic function is in normal condition, prevent pernicious anaemia；Nervous system health is safeguarded, the effect for the treatment of is doubled.
Embodiment
With reference to specific embodiment, the invention will be further described：
Medicinal powder of the present invention is according to theory of traditional Chinese medical science, diagnosis and treatment based on an overall analysis of the illness and the patient's condition, using multi-medicament use in conjunction, coordinate all warps by exciting for the clinical symptoms of patients with ankylosing spondylitis, play Yin Yang balancing, resist disease and evil, temperature compensation governor vessel, strengthen true strength, warm venting QI-blood, adjust actual situation the effect of；Multi-medicament use in conjunction plays a part of analgesic, muscle-growing and detumescence, promoting blood circulation and removing blood stasis, dredging collateral, and can treat both principal and secondary aspect of disease, have no side effect, be cheap.
Embodiment
The Chinese medicine material composition of the present invention：
It is a kind of treat ankylosing spondylitis superintend and direct moxibustion powder, it is characterized in that, be made up of the Chinese medicine material and Western medicine raw material of following weight proportion：
Chinese medicine material：Pawpaw 100g,Caulis piperis futokadsurae 150g,Long-nosed pit viper 100g,Polygonum multiflower knotweed 100g,Turmeric 100g,Sargentodoxa cuneata 120g,Frankincense 50g,Myrrh 50g,Lycopodium calvatum 100g,Clerodendron trichotomum 100g,Caulis sinomenii 100g,Smilax 100g,Bark of ash 100g,Levisticum 100g,Madder 50g,Giant knotweed 150g,Ligusticum wallichii 100g,Bush 50g,Red sage root 150g,Safflower 100g,Peach kernel 100g,Moschus 1g,Borneol 1.5g,Asian puccoon 100g,Folium isatidis 100g,Airpotato yam 50g,Field pennycress 100g,Cymose buckwheat rhizome 100g,Centipede 50g,Hippocampus 3 0g,Rhizoma homalonemae 50g,Scorpio 50g,Root of Chinese clematis 50g,Morinda officinalis 50g,Cortex acanthopanacis 150g,Ramulus Taxilli 100g,Reticulate millettia 150g,Rhizoma cibotii 150g,Pyrola 100g,Rhizoma Gastrodiae 50g,Rhizoma Corydalis (processed with vinegar) 50g,Datura flower 3g；
Western medicine raw material：Thiamine Hydrochloride Tablets（10mg/ pieces）10；Vitamin B12 piece（25ug/ pieces）40；
Above-mentioned raw materials medicine is prepared according to the following steps：
（1）By in above-mentioned Chinese medicine material：Pawpaw 100g,Caulis piperis futokadsurae 150g,Long-nosed pit viper 100g,Polygonum multiflower knotweed 100g,Turmeric 100g,Sargentodoxa cuneata 120g,Lycopodium calvatum 100g,Clerodendron trichotomum 100g,Caulis sinomenii 100g,Smilax 100g,Bark of ash 100g,Levisticum 100g,Madder 50g,Giant knotweed 150g,Ligusticum wallichii 100g,Bush 50g,Red sage root 150g,Safflower 100g,Peach kernel 100g,Asian puccoon 100g,Folium isatidis 100g,Airpotato yam 50g,Field pennycress 100g,Cymose buckwheat rhizome 100g,Centipede 50g,Hippocampus 3 0g,Rhizoma homalonemae 50g,Scorpio 50g,Root of Chinese clematis 50g,Morinda officinalis 50g,Cortex acanthopanacis 150g,Ramulus Taxilli 100g,Reticulate millettia 150g,Rhizoma cibotii 150g,Pyrola 100g,Rhizoma Gastrodiae 50g,Co-grinding is into fine powder after Rhizoma Corydalis (processed with vinegar) 50g is dried,Using being divided into 10 parts after ethylene oxide sterilizing,Plastic packaging is in standby in polybag；
（2）Frankincense 50g, myrrh 50g, Moschus 1g, borneol 1.5g, datura flower 3g are individually ground into fine powder, mixing is divided into 10 parts after using ethylene oxide sterilizing, and plastic packaging is in standby in polybag；
（3）Used time takes Thiamine Hydrochloride Tablets（10mg/ pieces）1, vitamin B12 piece（25ug/ pieces）4 are ground into fine powder and step（1）、（2）In standby medicinal powder it is each a well mixed, finally to superintend and direct moxibustion powder.
The application method of the present invention：It is II levels that order, which is diagnosed as ankylosing spondylitis Pain Grading,：X ray examinations：Articulatio sacroiliaca sawtooth sample changes, part ligament calcification, Minor articulus destruction of bone.The naked back of the body prostrate of 25~58mm/h of erythrocyte sedimentation rate patient is on bed, taking governor vessel big vertebra to the backbone position of Yaoshu(Du 2).To smear ginger juice in therapentic part after 75% alcohol disinfecting, sprinkled again on therapentic part and superintend and direct moxibustion powder, mulberry paper is covered thereon afterwards, then moxa cone finally is placed above in ginger mud, then lights in mulberry paper upper berth ginger mud such as scalariform again, ginger mud and Chinese mugwort ash are removed after continuous moxibustion treatment, then therapentic part is wiped clean with damp and hot towel, once, 10 times are a course for the treatment of for treatment in every 5 days.
Pharmacology analysis of the present invention
In raw material of the present invention：1. pawpaw, caulis piperis futokadsurae, long-nosed pit viper, Polygonum multiflower knotweed, turmeric, sargentodoxa cuneata-promoting blood circulation, swelling and pain relieving, dispelling wind and removing obstruction in the meridians；2. frankincense, myrrh-promoting blood circulation and stopping pain, detumescence and promoting granulation；3. lycopodium calvatum, clerodendron trichotomum, caulis sinomenii-relaxing tendons and activating collaterals；4. smilax, bark of ash, levisticum-removing toxic substances, dampness removing is easing joint movement；5. madder, giant knotweed, Ligusticum wallichii, bush, the red sage root, peach kernel, safflower, Rhizoma Corydalis (processed with vinegar)-promoting blood circulation, swelling and pain relieving；6. Moschus, borneol-blood circulation promoting and dispersing pathogen accumulation, swelling and pain relieving;7. Asian puccoon, folium isatidis, field pennycress, airpotato yam, cymose buckwheat rhizome-removing toxicity for detumescence, promoting blood circulation and removing blood stasis；8. rhizoma Gastrodiae, scorpio, centipede-strengthening the bones and muscles, blood circulation promoting and dispersing pathogen accumulation, swelling and pain relieving；9. Morinda officinalis, rhizoma homalonemae, cortex acanthopanacis, Ramulus Taxilli, reticulate millettia, rhizoma cibotii, pyrola, hippocampus-wind-damp dispelling, filling liver kidney, strengthening the bones and muscles；10. datura flower, the root of Chinese clematis-relieving spasm and pain；11. vitamin B1, vitamin B12 piece-maintenance nerve fiber, the metabolism of muscle activity and function are normal.
1. promoting blood circulation, swelling and pain relieving, dispelling wind and removing obstruction in the meridians：The active factors in pawpaw, caulis piperis futokadsurae, long-nosed pit viper, Polygonum multiflower knotweed, turmeric, sargentodoxa cuneata in raw material can play promoting blood circulation, swelling and pain relieving, the effect of dispelling wind and removing obstruction in the meridians rapidly.Modern pharmacological research shows：Pawpaw contains a variety of chemical compositions, mainly there is the compositions such as first Pentacyclic triterpene saponins compounds, lignanoid's glycosides compound, flavonoids and phenol, has analgesia, the pharmacological activity of anti-inflammatory；The active ingredients such as the ketone that contains in caulis piperis futokadsurae, alcohol, alkaloids, volatile oil, there is anti-inflammatory, analgesic, oxidation resistant effect；The active ingredients such as the amino acid and protein in long-nosed pit viper also have analgesia, calm antithrombus formation well, promote the effect of blood flow, diseased region can be promoted to recover normal function rapidly；Polygonum multiflower knotweed master contains rheum emodin, and Physcion, also this glucoside of acetyl containing Polygonum multiflower knotweed have the function that calmness, dredging the channel, antipruritic；Curcumin and volatile oil contained by turmeric have anti-inflammatory, antimycotic and oxidation resistant effect；The main chemical compositions of sargentodoxa cuneata have phenolic acid class, Anthraquinones, flavonoids, total saposins, tannin class etc., and its pharmacological action also has the effect such as antibacterial, antiviral, anti-inflammatory, antitumor.
2. promoting blood circulation and stopping pain, detumescence and promoting granulation：The active factors in frankincense, myrrh in raw material can play promoting blood circulation and stopping pain, the effect of detumescence and promoting granulation rapidly.Modern pharmacological research shows：Both medicines also contain a variety of antibiotic, and resin contained therein, natural gum, volatile oil have stronger analgesic activity, good analgesic activity can be played to patient.
3. relaxing tendons and activating collaterals：Lycopodium calvatum, clerodendron trichotomum, caulis sinomenii in raw material play the role of good relaxing tendons and activating collaterals.Modern pharmacological research shows：Lycopodium calvatum contains the sterols such as terpenoid, cupreol such as the alkaloid such as lycopodine, rod lycoclavanin alkali, lycopod triol, the alcohol ketone of lycopod four, and vanillic acid, forulic acid etc., Clavatol extract have obvious analgesic activity；Clerodendron trichotomum contains benzyl carbinol glycosides, brass, alkaloid etc., has the function that anti-inflammatory, anti-oxidant, calm；Caulis sinomenii master containing alkaloid, sterol, there is dispelling wind and eliminating pain, anti-inflammatory.
4. removing toxic substances, dampness removing is easing joint movement：Smilax, bark of ash, levisticum in raw material have removing toxic substances well, dampness removing, easing joint movement effect.Modern pharmacological research shows：The many kinds of substance such as pachymaran, protein, lecithin has anticancer, the effect of dispersing swelling and dissipating binds contained by smilax, and contained Astilbin has obvious analgesic activity.Gentianin contained by bark of ash has the function that anti-inflammatory.Active ingredient contained by levisticum has calmness, hypnosis, analgesic effect, and there is antiinflammatory action, contained bergapten, xanthotoxin etc. to have photosensitive and antitumor action for contained osthole and xanthotoxin.
5. promoting blood circulation, swelling and pain relieving：Madder, giant knotweed in raw material, Ligusticum wallichii, bush, the red sage root, peach kernel, safflower, Rhizoma Corydalis (processed with vinegar) have promoting blood circulation, the effect of swelling and pain relieving.Modern pharmacological research shows：Contained triterpenes, saponin(e, amino acid, flavones, sugar and a variety of inorganic elements in madder, giant knotweed, Ligusticum wallichii, bush, the red sage root, peach kernel, safflower, Rhizoma Corydalis (processed with vinegar), there is antifatigue, anti anoxia, immunological regulation, treat the effect such as sore carbuncle.
6. blood circulation promoting and dispersing pathogen accumulation, swelling and pain relieving：Moschus, borneol in raw material play the role of blood circulation promoting and dispersing pathogen accumulation, swelling and pain relieving.Modern pharmacological research shows：Contained cinnaldehydrum in Moschus, ketone, alkenes composition, alkaloids, volatile oil act on very strong analgesia, anti-inflammatory etc..Borneol also has anti-inflammatory, analgesia, bidirectional modulation nervous system, improves the effect of other drugs bioavilability.
7. removing toxicity for detumescence, promoting blood circulation and removing blood stasis：Asian puccoon, folium isatidis, field pennycress, airpotato yam, cymose buckwheat rhizome in raw material have very strong removing toxicity for detumescence, effect promoting blood circulation and removing blood stasis.Modern pharmacological research shows：Contained alkaloid in Asian puccoon, folium isatidis, field pennycress, airpotato yam, cymose buckwheat rhizome, non-alkaloid and kind more than 20 have calmness, spasmolysis, immunological regulation, anti-radiation, antineoplastic effective composition, so as to improve oedema, the pain that back caused by acute ankylosing spondylitis is organized.
8. strengthening the bones and muscles, blood circulation promoting and dispersing pathogen accumulation, swelling and pain relieving：Rhizoma Gastrodiae, scorpio, centipede in raw material can effective strengthening the bones and muscles, blood circulation promoting and dispersing pathogen accumulation, swelling and pain relieving.Modern pharmacological research shows：Contained water-soluble polysaccharide, methanol, glucosides have calmness, hypnosis, increase the effect of intelligence, cerebrum tonifying, brain tonic, improving eyesight, anti-inflammatory, immune enhancing in rhizoma Gastrodiae, to the elderly's anti-aging, extend the life-span, to a middle-aged person's dispelling fatigue, keep abundant muscle power, teenager is strengthened and remembered, it is highly beneficial to improve eyesight；There is scorpion venom in scorpio detumescence to stop convulsion, analgesic effect；Fat oil, cholesterine, formic acid volatile oil in centipede have the function that antitumor, antibacterial, promote immunologic function.
9. wind-damp dispelling, filling liver kidney, strengthening the bones and muscles：A variety of alkaloids that Morinda officinalis, rhizoma homalonemae in raw material, cortex acanthopanacis, Ramulus Taxilli, reticulate millettia, rhizoma cibotii, pyrola, hippocampus contain, volatile oil have a very strong wind-damp dispelling, filling liver kidney, the effect of strengthening the bones and muscles, and modern pharmacological research shows：The steroid saponin that contains in Morinda officinalis, rhizoma homalonemae, cortex acanthopanacis, Ramulus Taxilli, reticulate millettia, rhizoma cibotii, pyrola, hippocampus, flavonoid glycoside, amino acid etc. have the function that antitumor, hemostasis, analgesia, regulation are immune.
10. relieving spasm and pain：The active ingredient of datura flower, the root of Chinese clematis in raw material has the function that relieving spasm and pain, and modern pharmacological research shows：Alkaloid in datura flower has anesthesia, spasmolysis, analgesic effect to diseased region, the root of Chinese clematis is the key medicine for the treatment of numbness pain contraction, the compositions such as contained protoanemonin, sugared saponin also have the function that anti-inflammation, can prevent injury due to oedema, caused by inflammatory infiltration.
11. safeguard metabolism and the function of neural myelin：Vitamin B1, vitamin B12 in raw material can safeguard metabolism and the function of neural myelin, promote the reparation of injured nerve root, and nerve fiber, the metabolism of muscle activity and function can be maintained normal, promote development and the maturation of red blood cell, human body hematopoietic function is set to be in normal condition, prevent pernicious anaemia, safeguard nervous system health.
Pharmacodynamics statistics of the present invention：
1. general clinical data：Choose the same period and move in our hospital, it is II levels to be diagnosed as ankylosing spondylitis Pain Grading：X ray examinations：Articulatio sacroiliaca sawtooth sample changes, part ligament calcification, Minor articulus destruction of bone.25~58mm/h of erythrocyte sedimentation rate patient 218, is randomly divided into two groups；Treatment group 109, man 73, female 36；It is 18.48~39.42 years old age, average 26.32 years old；Control group 109, man 68, female 40 are 17.72~41.34 years old age, average 27.82 years old；The two random groups patient compares in sex, age, nutrition condition etc., no significant difference（P ＞ 0.05）.
2. treatment method：Control group patient give conventional therapy：The medicines such as Indomethacin, brufen and feldene taken before sleeping 50 days be a course for the treatment of；Treatment group patient treats on the basis of conventional therapy plus with moxibustion treatment is superintended and directed, and once, 10 times are a course for the treatment of for treatment in every 5 days.
3. evaluation index：Reference《New Chinese medicine guideline of clinical investigations》The effect of middle standard：1. clinical recovery：Tcm clinical practice symptom, sign disappear or basic disappearance, syndrome integral reduce >=95%；It is 2. effective：Tcm clinical practice symptom, sign disappear or basic disappearance, syndrome integral reduce >=70%；It is 3. effective：Tcm clinical practice symptom, sign disappear or basic disappearance, syndrome integral reduce >=30%；It is 4. invalid：Tcm clinical practice symptom, sign are not improved or aggravated, and syndrome integral reduces ﹤ 30%.
4. statistical method：Using the progress data analysis of SPSS13.0 statistical analysis softwares, between two groups, curative effect compares is examined using x2, and measurement data is examined using t, and p ﹤ 0.05 are that difference is statistically significant.
Table 1：Two groups of patient outcomes compare [example after a course for the treatment of（%）]
Note：The p of χ 2=11.74 compared with control group<0.05 there were significant differences
Table 2：Two groups of patient outcomes compare [example after two courses for the treatment of（%）]
Note：The p of χ 2=15.82 compared with control group<0.05 there were significant differences
5. conclusion：Two groups of patient outcomes compare after two courses for the treatment of, understand that the cure rate for the treatment of group is statistically significant apparently higher than control group, difference by table 1, table 2（P ＜ 0.05）.Medicinal powder of the present invention applies the infringement to human body for avoiding oral application Western medicine outside simultaneously and partial closure is damaged to caused by patient and the feared state of mind.
Claims (2)
1. it is a kind of treat ankylosing spondylitis superintend and direct moxibustion powder, it is characterized in that, be made up of the Chinese medicine material and Western medicine raw material of following weight proportion：
Chinese medicine material：Pawpaw 100g,Caulis piperis futokadsurae 150g,Long-nosed pit viper 100g,Polygonum multiflower knotweed 100g,Turmeric 100g,Sargentodoxa cuneata 120g,Frankincense 50g,Myrrh 50g,Lycopodium calvatum 100g,Clerodendron trichotomum 100g,Caulis sinomenii 100g,Smilax 100g,Bark of ash 100g,Levisticum 100g,Madder 50g,Giant knotweed 150g,Ligusticum wallichii 100g,Bush 50g,Red sage root 150g,Safflower 100g,Peach kernel 100g,Moschus 1g,Borneol 1.5g,Asian puccoon 100g,Folium isatidis 100g,Airpotato yam 50g,Field pennycress 100g,Cymose buckwheat rhizome 100g,Centipede 50g,Hippocampus 3 0g,Rhizoma homalonemae 50g,Scorpio 50g,Root of Chinese clematis 50g,Morinda officinalis 50g,Cortex acanthopanacis 150g,Ramulus Taxilli 100g,Reticulate millettia 150g,Rhizoma cibotii 150g,Pyrola 100g,Rhizoma Gastrodiae 50g,Rhizoma Corydalis (processed with vinegar) 50g,Datura flower 3g；
Western medicine raw material：Thiamine Hydrochloride Tablets（10mg/ pieces）10；Vitamin B12 piece（25ug/ pieces）40；
Above-mentioned raw materials medicine is prepared according to the following steps：
（1）By in above-mentioned Chinese medicine material：Pawpaw 100g,Caulis piperis futokadsurae 150g,Long-nosed pit viper 100g,Polygonum multiflower knotweed 100g,Turmeric 100g,Sargentodoxa cuneata 120g,Lycopodium calvatum 100g,Clerodendron trichotomum 100g,Caulis sinomenii 100g,Smilax 100g,Bark of ash 100g,Levisticum 100g,Madder 50g,Giant knotweed 150g,Ligusticum wallichii 100g,Bush 50g,Red sage root 150g,Safflower 100g,Peach kernel 100g,Asian puccoon 100g,Folium isatidis 100g,Airpotato yam 50g,Field pennycress 100g,Cymose buckwheat rhizome 100g,Centipede 50g,Hippocampus 3 0g,Rhizoma homalonemae 50g,Scorpio 50g,Root of Chinese clematis 50g,Morinda officinalis 50g,Cortex acanthopanacis 150g,Ramulus Taxilli 100g,Reticulate millettia 150g,Rhizoma cibotii 150g,Pyrola 100g,Rhizoma Gastrodiae 50g,Co-grinding is into fine powder after Rhizoma Corydalis (processed with vinegar) 50g is dried,Using being divided into 10 parts after ethylene oxide sterilizing,Plastic packaging is in standby in polybag；
（2）Frankincense 50g, myrrh 50g, Moschus 1g, borneol 1.5g, datura flower 3g are individually ground into fine powder, are well mixed, using being divided into 10 parts after ethylene oxide sterilizing, plastic packaging is in standby in polybag；
（3）Used time takes Thiamine Hydrochloride Tablets（10mg/ pieces）1, vitamin B12 piece（25ug/ pieces）4 are ground into fine powder and step（1）、（2）In standby medicinal powder it is each a well mixed, finally to superintend and direct moxibustion powder.
2. a kind of method for preparing ankylosing spondylitis and superintending and directing moxibustion powder, it is characterized in that：The bulk drug is prepared according to the following steps：
（1）By in above-mentioned Chinese medicine material：Pawpaw 100g,Caulis piperis futokadsurae 150g,Long-nosed pit viper 100g,Polygonum multiflower knotweed 100g,Turmeric 100g,Sargentodoxa cuneata 120g,Lycopodium calvatum 100g,Clerodendron trichotomum 100g,Caulis sinomenii 100g,Smilax 100g,Bark of ash 100g,Levisticum 100g,Madder 50g,Giant knotweed 150g,Ligusticum wallichii 100g,Bush 50g,Red sage root 150g,Safflower 100g,Peach kernel 100g,Asian puccoon 100g,Folium isatidis 100g,Airpotato yam 50g,Field pennycress 100g,Cymose buckwheat rhizome 100g,Centipede 50g,Hippocampus 3 0g,Rhizoma homalonemae 50g,Scorpio 50g,Root of Chinese clematis 50g,Morinda officinalis 50g,Cortex acanthopanacis 150g,Ramulus Taxilli 100g,Reticulate millettia 150g,Rhizoma cibotii 150g,Pyrola 100g,Rhizoma Gastrodiae 50g,Co-grinding is into fine powder after Rhizoma Corydalis (processed with vinegar) 50g is dried,Using being divided into 10 parts after ethylene oxide sterilizing,Plastic packaging is in standby in polybag；
（2）Frankincense 50g, myrrh 50g, Moschus 1g, borneol 1.5g, datura flower 3g are individually ground into fine powder, are well mixed, using being divided into 10 parts after ethylene oxide sterilizing, plastic packaging is in standby in polybag；
（3）Used time takes Thiamine Hydrochloride Tablets（10mg/ pieces）1, vitamin B12 piece（25ug/ pieces）4 are ground into fine powder and step（1）、（2）In standby medicinal powder it is each a well mixed, finally to superintend and direct moxibustion powder.
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