CN1072449C - Chewing gum with function of promoting absorption of effective components and its preparation - Google Patents
Chewing gum with function of promoting absorption of effective components and its preparation Download PDFInfo
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- CN1072449C CN1072449C CN98110216A CN98110216A CN1072449C CN 1072449 C CN1072449 C CN 1072449C CN 98110216 A CN98110216 A CN 98110216A CN 98110216 A CN98110216 A CN 98110216A CN 1072449 C CN1072449 C CN 1072449C
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Abstract
The present invention relates to chewing gum with the function of promoting the absorption of effective components and a preparation method thereof. The chewing gum is composed of one or several kinds of edible plants capable of adjusting the function of human bodies, a chewing gum base, essence, glycerol, powdered sugar, etc. The chewing gum is characterized in that an oral mucosa absorbent capable of promoting the sufficient absorption of the effective components of the functional plants in the oral cavity is added to the universal chewing gum recipe so as to further enlarge the range of the health function, and the permeation rate of the effective components in the oral cavity is increased more than 10 to 80 times; the bioavailability is increased obviously, and the effective components absorbed through the oral cavity are not affected by the liver and gastrointestinal destructive effects.
Description
The invention belongs to chewing gum and preparation method thereof, particularly relate to and contain that to derive from edible plants be raw-material chewing gum and preparation method.
People can increase salivary gland secretion mucoprotein, globulin, amino acid, ptyalin and lysozyme etc. by chew gum, the mechanism that medicine sees through oral mucosa is simple diffusion, meet PH-and distribute hypothesis, not influenced by the first pass effect of liver and enter whole body circulation through the active ingredient of the edible plants of membrana oralis mucosa absorption, avoided effective ingredients in plant to be subjected to the influence of gastrointestinal content and pH value, reduce that active ingredient concentration peak valley changes in the blood, reduce plant to GI toxic reaction etc.The document that the inventor is related to the present invention by retrieval, the application for a patent for invention of publication number CN1091569A, it relates to a kind of serial Chinese medicine health-care processes for producing chewing gums, relating to crow sends out, increases and look, promote longevity, rejuvenate, remove the newborn addiction and six the treatment aspects that desensitize, but, because the major function of oral mucosa is exactly barrier action to external world,, be difficult to reach the effect of anticipation so its active ingredient is to be difficult for seeing through and effectively being absorbed.Existing commercially available " hair-blacking toothpaste " and through health food--the American ginseng lozenge of the hygienic food and health number (1997) the 203rd of Ministry of Public Health's approval, promptly be the active ingredient that absorbs health products by oral cavity and gingival mucosa, but its infiltration rate and uptake are relatively poor, loss of effective components is bigger, has influenced health-care effect.
The present invention is exactly chewing gum and the preparation method who promotes the active ingredient absorption function that have who provides at the problems referred to above of prior art existence, its main purpose is to add on the one hand the edible plants that can regulate the function of human body effect in prescription, add the oral mucosa absorbent that fully absorbs in the oral cavity that promotes active ingredient on the other hand.
Above-mentioned purpose of the present invention realizes by the following technical solutions: add a kind of in chewing gum formulations or several can regulate the edible plants (hereinafter to be referred as the function plant) of function of human body effect, add the oral mucosa absorbent on the other hand, to reduce the screen-wall effect of oral mucosa, reach and promote the function effective components in plants, thereby can avoid the first pass effect of liver and active ingredient through intestines and stomach the time, to be decomposed or destroy in intraoral abundant absorption.Add the oral mucosa absorbent, the transit dose of effective ingredient in the oral cavity improved more than 10-80 times, the absorption of function effective ingredients in plant is more abundant, and bioavilability significantly improves.
The selected function plant of the present invention is the edible plants with tonic function, and it has highlighted feature edible, that keep healthy, regulate function of human body and go back to nature, has demonstrated fully the feature of medicine food unification.The function plant made pulvis or, add in the manufacturing prescription of general chewing gum, can produce the serial chewing gum that the present invention has unique function through extracting, concentrate, be refined into liquid extract and an amount of oral mucosa absorbent.
Based on above-mentioned principle,, take following production technology for reaching the object of the invention:
1, the present invention presses surface compositions and selects batching (by weight percentage): function plant liquid extract 1.0～25%, oral mucosa absorbent 0.1～10%, chewing gum base 15～25%, essence 0.5～1.5%, glycerine 0.8～1.5%, surplus are dextrose syrup and Icing Sugar.
More than be the basic components of plain edition chewing gum of the present invention, add the acid type chewing gum and can add tartaric acid 0.5～1.5% in addition.
For making chewing gum have good chewiness and lasting fragrance, available sorbierite (70%), maltodextrin (5-10DE) replace dextrose syrup in addition, and its percentage by weight is sorbierite (70%) 5.0～15%, maltodextrin (5-10DE) 3.0～7.0%.
2, chewing gum base adds refining function plant liquid extract, oral mucosa absorbent and essence in preheating 3 hours at least below 48 degrees centigrade, stirs.
3, other various batchings are divided two batches of addings, stir.
4, tartaric acid in the end adds, and feed temperature should remain on 35-48 degree centigrade, and back cooling, compression moulding, packing stir.
8 kinds of function plants that the embodiment that the present invention selects for use relates to are verified the food plant with unique health care by modern science, and embodiment is as follows:
Embodiment 1: American Ginseng chewing gum and preparation
(1) American Ginseng: different name American ginseng, American ginseng, have the tonifying Qi of refreshing oneself, kidney is supported in enriching yin, the multiple special efficacies such as production of sperm, strengthening spleen and nourishing stomach and anti-ageing beauty treatment of enriching blood.Main component: total saponins of American ginseng, total polysaccharide.
Advantage:
1. antifatigue effect has tangible elimination organism fatigue, and it is powerful to regain one's vigor rapidly.
2. immunoregulation effect can significantly improve body's immunity, strengthens Abwehrkraft des Koepers.
3. resisting oxygen lack.Prolong the body hypoxia-bearing time, have the effect of obviously building up health.
American ginseng is extracted, concentrates, is refined into liquid extract, and its liquid extract is 1: 10 with the pulvis ratio of American ginseng.
(2) press surface compositions than selecting batching (percentage by weight): component is than specification A1 B2 A2 B2 A3 B3 component American ginseng liquid extract 7.5 9.5 11.3 11.3 15 20 matrixs 20 25 22 19 18 15 essence 1.0 1.2 0.8 1.1 0.5 0.7 glycerine 1.5 1.0 0.9 1.2 0.8 1.1 sorbierites 70% 10.0 9.0 12.0 7.0 15.0 11.0 maltodextrin (5-10DE) 3.0 5.0 6.0 7.0 4.0 5.0 tartaric acid---and 0.5---1.0---1.5 NaGC 6.0 2.5 2.0 3.8 4.5 5.5 surpluses are that Icing Sugar is annotated: A is the plain edition chewing gum, and B is for adding the acid type chewing gum.
(3) matrix is below 48 Celsius temperatures preheating 3-4 hour at least, adds American ginseng liquid extract or pulvis, oral mucosa absorbent (NaGC) and essence, stirs.
(4) divide two batches to add other batching, after earlier 1/2 Icing Sugar, 1/2 maltodextrin, 1/2 sorbierite (70%) and glycerine being stirred, add the residue batching again and stir.
(5) tartaric acid adds at last, and feed temperature is the 40-48 degree, cooling compression moulding packing.
(6) usage and dosage: chew, each one, every day 2-4 time, but dosage when needing, it is better to take effect for a long time.
(7) suitable crowd: adult's (be specially adapted to be engaged in nervous mental and heavy physical labor person, stay up late, work overtime, sick empty weakling, boss, manager, driver, student and middle old man's daily health caring).
Embodiment 2: the preparation of ginseng gum drop
(1) genseng: reinforce vital energy, multiple arteries and veins takes off admittedly, reinforces the spleen to benefit the lung, and is promoting production of body fluid and inducing sedation of the mind.Be used for body void and desire to take off, the cold weak pulse of limb, insufficiency of the spleen food is few, and the deficiency syndrome of the lung is breathed with cough, and interior heat is quenched one's thirst, and prolonged illness void is won, the palpitation with fear insomnia, the impotence palace is cold.
Main component: panaxoside, panaxynol etc.Genseng has " adapting to former " sample effect, can strengthen corticocerebral excited process, improves people's the mentality and the function of muscle power, and antifatigue effect is very remarkable.
Genseng is extracted, concentrates, is refined into liquid extract, and its liquid extract is 1: 10 with genseng pulvis ratio.
(2) press surface compositions than selecting batching (percentage by weight): component is than specification A1 B1 A2 B2 A3 B3 component ginseng liquid extract 4.5 4.0 10.0 12.0 20.0 22.5 matrixs 25 22 20 18 17 15 essence 1.5 1.3 1.0 0.8 0.7 0.5 glycerine 1.0 0.8 1.1 0.9 1.2 1.5 sorbierites 70% 12 11 8.0 7.0 10.0 15 maltodextrin (5-10DE) 7.0 5.0 6.0 4.5 3.0 5.5 tartaric acid---and 1.0---1.0---1.0 TA 1.5 1.5 1.5 1.5 1.5 1.5 surpluses are that Icing Sugar is annotated: A is the plain edition chewing gum, and B is for adding the acid type chewing gum.
(3) matrix is below 48 Celsius temperatures preheating 3-4 hour at least, adds ginseng liquid extract or pulvis, oral mucosa absorbent (TA) and essence, stirs.
(4) add 1/2 Icing Sugar, 1/2 maltodextrin, 1/2 sorbierite (70%) and glycerine stir in batches.
(5) tartaric acid adds at last, and feed temperature is the 35-48 degree, cooling compression moulding packing.
(6) usage and dosage: chew, each one, every day 2 times, but dosage when needing, it is better to take effect for a long time.
(7) taboo: the case of a physically strong patient running a high fever, heat symptom-complex person avoid clothes.
Embodiment 3: the preparation of fruit of Chinese magnoliavine chewing gum
(1) the herbal cloud of the fruit of Chinese magnoliavine (fructus schisandrae): " male sexuality does not rise, clothes one hundred days, and detachable ten woman, 4 o'clock are not exhausted ".
Active ingredient: schizandrin, deoxyschisandrin, schisandrol etc.Its effect is that nerve is had excitation, strong effect.Dosage reaches 9 grams, then causes the motility excitement.Can improve the intellection of human body, increase work efficiency.Fructus schisandrae is similar to genseng, and " adapting to former " sample effect is arranged.
Liquid extract is extracted, concentrated, is refined into to the fruit of Chinese magnoliavine, and its liquid extract is 1: 10 with fruit of Chinese magnoliavine pulvis ratio.
(2) press surface compositions than selecting batching, (percentage by weight): component is than specification A1 B1 A2 B2 A3 B3 component fruit of Chinese magnoliavine liquid extract 2.0 3.5 5.0 8.0 10 15 matrixs 25 20 18 17 19 15 essence 0.7 0.5 1.0 0.6 0.8 1.2 glycerine 1.5 1.0 1.2 1.1 0.7 0.9 sorbierites 70% 15 12 10 8.0 7.0 5.0 maltodextrin, (5-10DE) 3.0 4.0 5.0 6.0 6.5 7.0 tartaric acid---0.6---1.0---, 1.5 propane diols: azone, (4; 1) 5.0 5.5 6.5 8.0 10 9.0 surpluses are that Icing Sugar is annotated:A is the plain edition chewing gum, and B is for adding the acid type chewing gum.
(3) matrix preheating 3 hours at least below 48 Celsius temperatures adds American ginseng liquid extract or pulvis, oral mucosa absorbent (mixture of propane diols and azone), essence stirs.
(4), (5), (6), (7) are with example 1.
Embodiment 4: the preparation of barrenwort chewing gum
(1) barrenwort: another name HERBA EPIMEDII, herbal cloud: " clothes make the people, there is excessive sheep the northwest, closes for hundred times on the one, due to the lid food leaves of pulse plants, so a barrenwort " well for negative and positive.
Composition: flavone compound, urge excessive effect.
Barrenwort is extracted, concentrates, is refined into liquid extract, and its liquid extract is 1: 10 with barrenwort pulvis ratio.
(2) press surface compositions than selecting batching (percentage by weight): component is than specification A1 B1 A2 B2 A3 B3 component barrenwort liquid extract 3.0 5.0 10 15 22.5 25 matrixs 25 22 20 18 16 15 essence 1.5 1.2 0.9 0.9 0.5 0.7 glycerine 1.5 1.2 1.0 0.8 0.6 0.5 sorbierites 70% 13 10.0 11.0 12.0 0.8 0.6 tartaric acid---and 0.6---0.9---1.3Azone 1.5 2.0 3.0 3.5 4.0 4.5 surpluses are that Icing Sugar and dextrose syrup are annotated: A is the plain edition chewing gum, and B is for adding the acid type chewing gum.
(3) matrix preheating 3 hours at least below 48 Celsius temperatures adds barrenwort liquid extract or pulvis, dodecyl ammonia heterocycle heptanone (Azone) and essence, stirs.
(4) divide two batches of addings, first adds 1/2 Icing Sugar,, 1/2 sorbierite (70%) and whole glycerine stirs; All the other second batch of addings.
(5) tartaric acid adds at last, and feed temperature is the 35-48 degree, cooling compression moulding packing.
(6) usage and dosage: chew, each one, every day 2-4 time, dosage when needing, it is better to take effect for a long time.
(7) be not suitable for the crowd: children are difficult for taking.
Embodiment 5: the preparation of frutus cnidii chewing gum:
(1) frutus cnidii: herbal cloud: " impotence in male, strong man is cloudy, good color, big Yiyang thing ".
Active ingredient: cumarin, Osthole.
Frutus cnidii is extracted, concentrates, is refined into liquid extract, and its liquid extract is 1: 10 with frutus cnidii pulvis ratio.
(2) press surface compositions than selecting batching (percentage by weight): component is than specification A1 B1 A2 B2 A3 B3 component frutus cnidii liquid extract 2.0 4.0 8.0 10 15 20 matrixs 23 25 21 17 18 15 essence 1.4 1.3 1.0 0.9 0.6 0.8 glycerine 1.5 1.2 1.0 0.9 0.8 0.5 sorbierites 70% 13 10.0 11.0 12.0 0.8 0.6 maltodextrin (5-10DE) 5.0 4.0 3.0 4.5 6.0 7.0 tartaric acid---0.5---1.0---1.4Azone: propane diols (1: 2) 2.5 3.5 4.0 4.5 6.0 7.0 surpluses are that Icing Sugar is annotated: A is the plain edition chewing gum, and B is for adding the acid type chewing gum.
(3), (4), (5), (6), (7), (8) are with embodiment 4.
Embodiment 6: the preparation of safflower chewing gum
(1) safflower: composition: glycosides displayed, as carthamin, safflower quinone glucoside, neocarthamin etc.
Its effect:
1. excited heart reduces coronary resistance, increases coronary flow.
2. to expeirmental myocardial ischemia, hard plug of cardiac muscle or arrhythmia cordis etc. have antagonism in various degree.
3. has the microcirculation of improvement.
4. has effect for reducing blood fat.
5. has the heat of raising effect.
(2) press surface compositions than selecting batching (percentage by weight): component is than specification A1 B1 A2 B2 A3 B3 component safflower liquid extract 4.0 6.0 12 14 20 22 matrixs 23 25 22 19 17 15 essence 0.5 0.7 0.8 1.0 1.2 1.5 glycerine 0.5 0.7 1.5 1.2 0.8 0.6 sorbierites 70% 13 10.0 11.0 12.0 0.8 0.6 maltodextrin (5-10DE) 5.0 4.0 3.0 4.5 6.0 7.0 tartaric acid---and 0.6---0.9---1.3 oral mucosa absorbent 5.0 5.5 6.0 7.0 8.0 9.0 surpluses are that Icing Sugar is annotated: A is the plain edition chewing gum, and B is for adding the acid type chewing gum.
(3) matrix preheating 3 hours at least below 48 Celsius temperatures adds safflower liquid extract or pulvis, oral mucosa absorbent (for dodecyl ammonia heterocycle heptanone Azone is 1: 3 than propane diols) and essence, stirs.
(4), (5), (6) are with embodiment 4.
(7) suitable crowd: cardiovascular and cerebrovascular diseases, the auxiliary health care of hyperlipemia.
(8) be not suitable for the crowd: teenage inedibility below 18.
Embodiment 7: the preparation of cortex acanthopanacis chewing gum:
(1) cortex acanthopanacis composition: Syringin, multiple lignin glucoside, periplocin etc.
Its effect:
1. have than genseng better " adapting to former " sample effect, can significantly improve the low anti-ability of body.
2. can postpone the generation of tumour, stop the transfer of tumour.
3. have hypoglycemic activity, and the blood sugar that when insulin causes hypoglycemia, can raise.
4. reduce people's basic metabolism, anti-emergencing action aspect is better than panaxoside.
Cortex acanthopanacis is extracted, concentrates, is refined into liquid extract, and its liquid extract is 1: 10 with cortex acanthopanacis pulvis ratio.
(2) press surface compositions than selecting batching (percentage by weight):
Component is than specification A1 B1 A2 B2 A3 B3
---1.5---0.5---1.0Lepaloine 1.0 1.5 2.5 3.5 4.5 5.5 surpluses are that Icing Sugar and dextrose syrup are annotated: A is the plain edition chewing gum to component cortex acanthopanacis liquid extract 7.0 9.3 11 17.5 22.5 25 matrixs 25 20 19 18 17 15 essence 0.5 0.7 0.9 1.1 1.3 1.5 glycerine, 1.5 1.2 1.0 0.9 0.5 0.7 maltodextrins (5-10DE) 3.0 5.0 4.0 6.0 7.0 3.5 tartaric acid, and B is for adding the acid type chewing gum.
Lepaloine is the natural oral cavity mucosa absorption agent of extracting from ledum palustre dilatatum.
(3), (4), (5), (6), (7) are with example 1.
Embodiment 8: the preparation of ganoderma lucidum chewing gum
(1) glossy ganoderma composition: ganodermal drop, 17 seed amino acids and various trace elements and organic germanium.
Its effect: the yang-tonifying of establishing the yang function, nourishing heart clears away heart-fire, and supports the lung clearing lung-heat, the nourishing the stomach clearing stomach, the benefit that makes eye bright is smart.Tool significantly improves body's immunity, increases leucocyte.
Glossy ganoderma is prepared liquid extract, and its liquid extract is 1: 10 with glossy ganoderma pulvis ratio.
(2) press surface compositions than selecting batching (percentage by weight):
Component is than specification A1 B1 A2 B2 A3 B3 component glossy ganoderma liquid extract 7.5 9.5 11.3 11.3 15 20 matrixs 20 25 22 19 18 15 essence 1.0 1.2 0.8 1.1 0.5 0.7 glycerine 1.5 1.0 0.9 1.2 0.8 1.1 tartaric acid, and---0.5---1.0---1.5Azone 1.5 2.0 2.5 3.0 4.0 4.5 surpluses are that Icing Sugar and dextrose syrup are annotated: A is the plain edition chewing gum, and B is for adding the acid type chewing gum.
(3) matrix preheating 3 hours at least below 48 Celsius temperatures adds glossy ganoderma liquid extract (or pulvis), Azone and essence, stirs.
(4) divide two batches to add other batching, after earlier 1/2 Icing Sugar, 1/2 dextrose syrup and glycerine being stirred, add residue Icing Sugar and dextrose syrup again and stir.
(5) tartaric acid adds at last, and feed temperature is the 40-48 degree, stirs, and packs after the cooling compression moulding.
(6) usage and dosage: chew, each one, every day 2-4 time, but dosage when needing, it is better to take effect for a long time.
(7) suitable crowd: all-ages.
Advantage of the present invention is:
1, the peculiar taste that has namely kept general chewing gum makes again the effect scope of chewing gum further Enlarge.
2, increase the secretion of saliva by chew gum, effective ingredient is easily absorbed.
3, add the oral mucosa absorbent in the chewing gum, active ingredient is improved at the permeability in oral cavity More than 10-80 times, its bioavilability obviously improves.
4, the active ingredient by buccal absorption is not subjected to the impact of the first pass effect of liver to enter the whole body Circulation has avoided active ingredient to be subjected to the impact of gastrointestinal content pH value, reduces function plant in the blood The peak valley of active ingredient concentration changes, and reduces and pays reaction etc. to stomach toxicity.
5, adopt maltodextrin, 70% concentration sorbierite, replacement glucose syrup, make the chewing gum tool Good chewiness and permanent fragrant are arranged.
6, several chewing gums are matched, and effect is better.
Claims (6)
1, a kind of chewing gum with promotion active ingredient absorption function, contain edible plants, chewing gum base, essence, glycerine Icing Sugar and the dextrose syrup surplus of regulating the function of human body effect, it is characterized in that in general chewing gum formulations, adding the oral mucosa absorbent 0.1-10% (by weight percentage) of the abundant absorption of active ingredient in the oral cavity that promotes the function plant.
2, according to the described chewing gum with promotion active ingredient absorption function of claim 1, the edible plants that it is characterized in that the effect of said adjusting function of human body is one or more in American Ginseng, genseng, the fruit of Chinese magnoliavine, barrenwort, frutus cnidii, the safflower.
3, according to claim 1 or 2 described chewing gums with promotion active ingredient absorption function, the edible plants that it is characterized in that the effect of said adjusting function of human body is a liquid extract, its content is 1.0-25%, and said chewing gum base is that 15-25%, essence are that 0.5-1.5%, glycerine Icing Sugar and dextrose syrup are surplus.
4, according to the described chewing gum of claim 1 with promotion active ingredient absorption function, it is characterized in that available sorbierite, maltodextrin replace dextrose syrup, its percentage by weight is 70% sorbierite 5.0-15%, maltodextrin 3.0-7.0%.
5, according to the described chewing gum of claim 1, it is characterized in that adding the acid type chewing gum and can add tartaric acid in addition with promotion active ingredient absorption function.
6, according to the described preparation method of claim 1 with the chewing gum that promotes the active ingredient absorption function, it is characterized in that chewing gum base preheating 3 hours at least below 48 Celsius temperatures, add function plant liquid extract, oral mucosa absorbent and essence, after stirring, divide two batches of addings with other various raw materials again, tartaric acid in the end adds.
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| Application Number | Priority Date | Filing Date | Title |
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| CN98110216A CN1072449C (en) | 1998-05-21 | 1998-05-21 | Chewing gum with function of promoting absorption of effective components and its preparation |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98110216A CN1072449C (en) | 1998-05-21 | 1998-05-21 | Chewing gum with function of promoting absorption of effective components and its preparation |
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| Publication Number | Publication Date |
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| CN1205841A CN1205841A (en) | 1999-01-27 |
| CN1072449C true CN1072449C (en) | 2001-10-10 |
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| CN98110216A Expired - Fee Related CN1072449C (en) | 1998-05-21 | 1998-05-21 | Chewing gum with function of promoting absorption of effective components and its preparation |
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| CN102302081A (en) * | 2011-08-26 | 2012-01-04 | 吉林紫鑫药业股份有限公司 | Ginseng and xylitol chewing gums and production process thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1106627A (en) * | 1994-11-25 | 1995-08-16 | 不二制油株式会社 | Production of chewing gum containing water soluble plant fibres and low caloric food |
| CN1144665A (en) * | 1995-09-04 | 1997-03-12 | 宋士杰 | Non-sugar defat chewing gum |
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1998
- 1998-05-21 CN CN98110216A patent/CN1072449C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1106627A (en) * | 1994-11-25 | 1995-08-16 | 不二制油株式会社 | Production of chewing gum containing water soluble plant fibres and low caloric food |
| CN1144665A (en) * | 1995-09-04 | 1997-03-12 | 宋士杰 | Non-sugar defat chewing gum |
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| CN1205841A (en) | 1999-01-27 |
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