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CN107183397A - Improve the preparation method of the feed addictive of quail immunologic function - Google Patents

Improve the preparation method of the feed addictive of quail immunologic function Download PDF

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Publication number
CN107183397A
CN107183397A CN201710246692.1A CN201710246692A CN107183397A CN 107183397 A CN107183397 A CN 107183397A CN 201710246692 A CN201710246692 A CN 201710246692A CN 107183397 A CN107183397 A CN 107183397A
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parts
taenian
capsule
stir
hooks
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苫君强
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/70Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75Feeding-stuffs specially adapted for particular animals for birds for poultry
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/20Animal feeding-stuffs from material of animal origin
    • A23K10/22Animal feeding-stuffs from material of animal origin from fish
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8988Gastrodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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Abstract

The invention discloses a kind of preparation method for the feed addictive for improving quail immunologic function, including:Rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian are rinsed with soda water, is rinsed;Drying to its water content is 15%;Using electron beam irradiation;Rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata are ground to form by particle using lapping device, is well mixed, obtains mixed material;Above-mentioned Chinese medicine will be extracted respectively with different concentration ethanol and water, obtain mixing filtrate;Ethanol is evaporated, the solid of water content≤10% is obtained, the solid powder that particle diameter is 200 μm is being ground to form into, then used in outside line light irradiation 10min, that is, obtain the feed addictive of described raising quail immunologic function.The feed addictive disclosed by the invention for improving quail immunologic function can not only effectively improve the survival rate of squealer.

Description

Improve the preparation method of the feed addictive of quail immunologic function
Technical field
The present invention relates to a kind of feed addictive, more particularly to a kind of system for the feed addictive for improving quail immunologic function Preparation Method.
Background technology
With China's expanding economy, birds animal husbandry has also obtained swift and violent development.Current birds raise predominantly big The concentration of scale formula is raised, and this yard feeding pattern is easy to monitor, managed and feeding, and cost-effective, but is due to not extensive Raise, which adds poultry disease infectious rate, once there are part birds to catch an illness, the infection of large area will soon be caused, Directly result in huge economic loss.
The content of the invention
It is an object of the invention to solve at least the above, and provide the advantage that at least will be described later.
It is a still further object of the present invention to provide a kind of feed addictive for improving quail immunologic function, it can not only have Effect improves the survival rate of squealer, and can effectively improve the resistance against diseases of quail.
In order to realize that there is provided a kind of feeding for improving quail immunologic function according to object of the present invention and further advantage The preparation method of feed additives, comprises the following steps:
It includes the raw material of following parts by weight:
10-20 parts of rhizoma Gastrodiae, 5-15 parts of yncaria stem with hooks, 5-15 parts of cassia seed, 10-15 parts of stir-baked FRUCTUS GARDENIAE, 5-15 parts of lophatherum gracile, radix scutellariae 5- 15 parts, 10-15 parts of the capsule of weeping forsythia, 1-10 parts of lotus nut, 5-15 parts of radix achyranthis bidentatae, 10-15 parts of Ligusticum wallichii, 5-15 parts of corydalis tuber, caulis bambusae in taenian 5-10 1-5 parts of part and ostreae testa pulverata;
Step 1, by water and sodium bicarbonate according to mass ratio it is 50:1 mixing, as in water bath sonicator, water bath sonicator is revived Fetch water;
Step 2, the soda water that step 1 is prepared is heated to 45 DEG C, rhizoma Gastrodiae, hook are rinsed using 45 DEG C of soda water Rattan, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian, rinse 10min Afterwards, then with temperature for 60 DEG C of clear water rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, bosom are rinsed The root of bidentate achyranthes, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian 50min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus The sub- heart, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian and ostreae testa pulverata are as in drying unit, at 100 DEG C, dry aqueous to its Measure as 15%;
Using electron beam irradiation rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried and is irradiated, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, light The leaf of bamboo, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata grind to form the particle that particle diameter is 70 μm, The rhizoma Gastrodiae of particle, yncaria stem with hooks will be ground to form, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, prolonged Hu Suo, caulis bambusae in taenian and ostreae testa pulverata are well mixed in the case where rotating speed is 50rpm as in agitating device, obtain mixed material;
Step 5, by the mixed material and the aqueous solution that are mixed to get by step 4 in mass ratio be 1:50 mixing, water bath sonicator, After ultrasonic 20min, at 170 DEG C after refluxing extraction 5h, filtering, obtain the first filtrate and the first filter residue, by the first filter residue with The ethanol solution that volumetric concentration is 85% is 1 in mass ratio:After 15 mixing, water bath sonicator, ultrasonic 30min, flowed back at 150 DEG C Extract after 4h, filtering obtains the second filtrate and the second filter residue, by the second filter residue with being pressed with volumetric concentration for 95% ethanol solution Mass ratio is 1:After 5 mixing, water bath sonicator, ultrasonic 30min, at 130 DEG C after refluxing extraction 4h, filtering obtains the 3rd filtrate, First filtrate, the second filtrate and the 3rd filtrate are mixed, obtain mixing filtrate;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, obtain water content≤ 10% solid, the powder that particle diameter is 200 μm is being ground to form by the solid, then used in outside line light irradiation 10min, that is, obtains described Raising quail immunologic function feed addictive.
Preferably, in the preparation method of the feed addictive of described raising quail immunologic function, including following weight The raw material of number:
10 parts of rhizoma Gastrodiae, 5 parts of yncaria stem with hooks, 15 parts of cassia seed, 15 parts of stir-baked FRUCTUS GARDENIAE, 5 parts of lophatherum gracile, 15 parts of radix scutellariae, 10 parts of the capsule of weeping forsythia, lotus 1 part of sub- 10 parts of the heart, 15 parts of radix achyranthis bidentatae, 15 parts of Ligusticum wallichii, 5 parts of corydalis tuber, 5 parts of caulis bambusae in taenian and ostreae testa pulverata.
Preferably, in the preparation method of the feed addictive of described raising quail immunologic function, including following weight The raw material of number:
20 parts of rhizoma Gastrodiae, 15 parts of yncaria stem with hooks, 5 parts of cassia seed, 10 parts of stir-baked FRUCTUS GARDENIAE, 15 parts of lophatherum gracile, 5 parts of radix scutellariae, 15 parts of the capsule of weeping forsythia, lotus 5 parts of sub- 1 part of the heart, 5 parts of radix achyranthis bidentatae, 10 parts of Ligusticum wallichii, 15 parts of corydalis tuber, 10 parts of caulis bambusae in taenian and ostreae testa pulverata.
Preferably, in the preparation method of the feed addictive of described raising quail immunologic function, including following weight The raw material of number:
15 parts of rhizoma Gastrodiae, 10 parts of yncaria stem with hooks, 10 parts of cassia seed, 12 parts of stir-baked FRUCTUS GARDENIAE, 10 parts of lophatherum gracile, 10 parts of radix scutellariae, 12 parts of the capsule of weeping forsythia, 2 parts of 6 parts of lotus nut, 10 parts of radix achyranthis bidentatae, 15 parts of Ligusticum wallichii, 10 parts of corydalis tuber, 7 parts of caulis bambusae in taenian and ostreae testa pulverata.
Preferably, in the preparation method of the feed addictive of described raising quail immunologic function, the irradiation of electron beam Dosage is 8Gy.
Preferably, in the preparation method of the feed addictive of described raising quail immunologic function, the irradiation of electron beam Time is 6min..
The present invention at least includes following beneficial effect:
1. a kind of feed addictive for raising quail immunologic function that the present invention is provided, including 10-20 parts of rhizoma Gastrodiae, yncaria stem with hooks 5- 15 parts, 5-15 parts of cassia seed, 10-15 parts of stir-baked FRUCTUS GARDENIAE, 5-15 parts of lophatherum gracile, 5-15 parts of radix scutellariae, 10-15 parts of the capsule of weeping forsythia, lotus nut 1- 1-5 parts of 10 parts, 5-15 parts of radix achyranthis bidentatae, 10-15 parts of Ligusticum wallichii, 5-15 parts of corydalis tuber, 5-10 parts of caulis bambusae in taenian and ostreae testa pulverata, rhizoma Gastrodiae also known as red Arrow, solely shake sesame, from it is female, close from grass, refreshing grass, yellow moccasin flower, Mokpo, RHIZONA GASTRODIAE, DINGFENGCAO, Bai Longpi, be orchid family Gastrodia for many years Raw herbaceous plant, root-like stock is plump, no greenery, capsule obovate elliptic, and often with stem tuber or seminal propagation, its rhizome enters medicinal With treat have a dizzy spell, the disease such as extremity numbness, child convulsion, be rare Chinese medicine, treatment headache and insomnia, hook shared with the precious ganoderma lucidum of fine jade Rattan is used as medicine with the stem branch of buckle, and it has The flat liver of heat-clearing, and dispelling wind and relieving convulsion effect, modern pharmacology experiment also confirms that yncaria stem with hooks has decompression to make With, therefore with very high medical value;The root of radix scutellariae is used as medicine, bitter, cold in nature, there is heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, peace The effects such as tire.Cure mainly warm heat disease, the infection of the upper respiratory tract, cough with lung heat, neonatal jaundice caused by dampness-heat, pneumonia, dysentery, hemoptysis, hot eyes, movement of the foetus not The diseases such as peace, hypertension, carbuncle swells furuncle sore;Lotus nut has antihypertensive effect, liensinine crystallization is proposed from lotus nut, there is of short duration decompression Effect, changes into quaternary ammonium salt, then strong and lasting antihypertensive effect occurs.Oxygen position methyl-liensinine Methylsulfate quaternary ammonium salt is walked to fan Ganglionic blocking action is strong and lasting, but causes not by vagus nerve lasting buck;Spinal cord cat and dog head cross-circulation Its Hypotensive Mechanism mainly peripheral action is all pointed out in experiment.The noncrystalline alkaloid Nn-9 of lotus nut, with stronger antihypertensive effect.It is yellow The clinical antibiotic property of a kind of reed mentioned in ancient books is better than the coptis, and does not develop immunity to drugs, containing more than 20 kinds of alkaloid in corydalis tuber, for promoting qi circulation and relieving pain, Promoting blood circulation to remove blood stasis, traumatic injury etc., caulis bambusae in taenian have clearing heat and eliminating phlegm, relieving restlessness, effect of preventing or arresting vomiting.For phlegm-heat cough, courage fire holds phlegm under the arm, shies Throb with fear not peaceful, vexed insomnia, middle wind phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pernicious vomiting, fetal irritability;Above-mentioned all medicines share is not only The survival rate of squealer can be effectively improved, and can effectively improve the resistance against diseases of quail, it can not only effectively be improved The survival rate of squealer, and can effectively improve the resistance against diseases of quail.
2. a kind of method of the feed addictive for raising quail immunologic function that the present invention is provided, by water and sodium bicarbonate according to Mass ratio is 50:1 mixing, as in water bath sonicator, water bath sonicator obtains soda water;The soda water that step 1 is prepared adds Heat to 45 DEG C, using 45 DEG C soda water rinse rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, Radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian, are rinsed after 10min, then rinse rhizoma Gastrodiae, yncaria stem with hooks, Cassia with the clear water that temperature is 60 DEG C Son, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian 50min;It will be rushed by step 2 Rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and bamboo after washing Eat and ostreae testa pulverata is as in drying unit, at 100 DEG C, drying to its water content is 15%;Using electron beam irradiation rhizoma Gastrodiae, Yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata;Adopt With lapping device by the rhizoma Gastrodiae after step 3 is dried and is irradiated, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, Lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata grind to form the particle that particle diameter is 70 μm, will grind to form the day of particle Fiber crops, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata As in agitating device, it is well mixed in the case where rotating speed is 50rpm, obtains mixed material;The mixing being mixed to get by step 4 is former Material is 1 in mass ratio with the aqueous solution:After 50 mixing, water bath sonicator, ultrasonic 20min, at 170 DEG C after refluxing extraction 5h, filtering, The first filtrate and the first filter residue are obtained, the ethanol solution for being 85% by the first filter residue and with volumetric concentration is 1 in mass ratio:15 mix Close, water bath sonicator, after ultrasonic 30min, at 150 DEG C after refluxing extraction 4h, filtering obtains the second filtrate and the second filter residue, will Second filter residue and the ethanol solution for being 95% with volumetric concentration are 1 in mass ratio:After 5 mixing, water bath sonicator, ultrasonic 30min, At 130 DEG C after refluxing extraction 4h, filtering obtains the 3rd filtrate, and first filtrate, the second filtrate and the 3rd filtrate are mixed, Obtain mixing filtrate;At 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, and obtains water content≤10% Solid, grinding to form particle diameter be 200 μm of powder by the solid, then used in outside line light irradiation 10min, that is, obtain described carry The feed addictive of high quail immunologic function;The present invention is essentially consisted in rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, Huang A kind of reed mentioned in ancient books, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata grind to form the particle of 70 μm of particle diameter, and it is conducive to second Extraction of the alcohol to active ingredient therein, while using the above-mentioned Chinese medicine of electron beam irradiation in the present invention, has not only acted as sterilization Effect, and can effectively remove aflatoxin therein, it is ensured that the quality of additive, while using three extracting process Effectively raise the extraction yield of traditional Chinese medicine ingredients.
Further advantage, target and the feature of the present invention embodies part by following explanation, and part will also be by this The research and practice of invention and be understood by the person skilled in the art.
Embodiment
The present invention is described in further detail below, to make those skilled in the art being capable of evidence with reference to specification word To implement.
It should be appreciated that such as " having ", "comprising" and " comprising " term used herein do not allot one or many The presence or addition of individual other elements or its combination.
Embodiment 1,
A kind of feed addictive for improving quail immunologic function is present embodiments provided, including:
Rhizoma Gastrodiae 10Kg, yncaria stem with hooks 5Kg, cassia seed 15Kg, stir-baked FRUCTUS GARDENIAE 15Kg, lophatherum gracile 5Kg, radix scutellariae 15Kg, capsule of weeping forsythia 10Kg, lotus Sub- heart 10Kg, radix achyranthis bidentatae 15Kg, Ligusticum wallichii 15Kg, corydalis tuber 5Kg, caulis bambusae in taenian 5Kg and ostreae testa pulverata 1Kg.
This implementation discloses a kind of method for the feed addictive for preparing and improving quail immunologic function and comprised the following steps:
Step 1, by water and sodium bicarbonate according to mass ratio it is 50:1 mixing, as in water bath sonicator, water bath sonicator is revived Fetch water;
Step 2, the soda water that step 1 is prepared is heated to 45 DEG C, rhizoma Gastrodiae, hook are rinsed using 45 DEG C of soda water Rattan, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian, rinse 10min Afterwards, then with temperature for 60 DEG C of clear water rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, bosom are rinsed The root of bidentate achyranthes, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian 50min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus The sub- heart, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian and ostreae testa pulverata are as in drying unit, at 100 DEG C, dry aqueous to its Measure as 15%;
Using electron beam irradiation rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried and is irradiated, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, light The leaf of bamboo, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata grind to form the particle that particle diameter is 70 μm, The rhizoma Gastrodiae of particle, yncaria stem with hooks will be ground to form, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, prolonged Hu Suo, caulis bambusae in taenian and ostreae testa pulverata are well mixed in the case where rotating speed is 50rpm as in agitating device, obtain mixed material;
Step 5, by the mixed material and the aqueous solution that are mixed to get by step 4 in mass ratio be 1:50 mixing, water bath sonicator, After ultrasonic 20min, at 170 DEG C after refluxing extraction 5h, filtering, obtain the first filtrate and the first filter residue, by the first filter residue with The ethanol solution that volumetric concentration is 85% is 1 in mass ratio:After 15 mixing, water bath sonicator, ultrasonic 30min, flowed back at 150 DEG C Extract after 4h, filtering obtains the second filtrate and the second filter residue, by the second filter residue with being pressed with volumetric concentration for 95% ethanol solution Mass ratio is 1:After 5 mixing, water bath sonicator, ultrasonic 30min, at 130 DEG C after refluxing extraction 4h, filtering obtains the 3rd filtrate, First filtrate, the second filtrate and the 3rd filtrate are mixed, obtain mixing filtrate;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, obtain water content≤ 10% solid, the powder that particle diameter is 200 μm is being ground to form by the solid, then used in outside line light irradiation 10min, that is, obtains described Raising quail immunologic function feed addictive.
Embodiment 2,
A kind of feed addictive for improving quail immunologic function is present embodiments provided, including:
Rhizoma Gastrodiae 20Kg, yncaria stem with hooks 15Kg, cassia seed 5Kg, stir-baked FRUCTUS GARDENIAE 10Kg, lophatherum gracile 15Kg, radix scutellariae 5Kg, capsule of weeping forsythia 15Kg, lotus Sub- heart 1Kg, radix achyranthis bidentatae 5Kg, Ligusticum wallichii 10Kg, corydalis tuber 15Kg, caulis bambusae in taenian 10Kg and ostreae testa pulverata 5Kg.
This implementation discloses a kind of method for the feed addictive for preparing and improving quail immunologic function and comprised the following steps:
Step 1, by water and sodium bicarbonate according to mass ratio it is 50:1 mixing, as in water bath sonicator, water bath sonicator is revived Fetch water;
Step 2, the soda water that step 1 is prepared is heated to 45 DEG C, rhizoma Gastrodiae, hook are rinsed using 45 DEG C of soda water Rattan, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian, rinse 10min Afterwards, then with temperature for 60 DEG C of clear water rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, bosom are rinsed The root of bidentate achyranthes, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian 50min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus The sub- heart, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian and ostreae testa pulverata are as in drying unit, at 100 DEG C, dry aqueous to its Measure as 15%;
Using electron beam irradiation rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried and is irradiated, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, light The leaf of bamboo, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata grind to form the particle that particle diameter is 70 μm, The rhizoma Gastrodiae of particle, yncaria stem with hooks will be ground to form, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, prolonged Hu Suo, caulis bambusae in taenian and ostreae testa pulverata are well mixed in the case where rotating speed is 50rpm as in agitating device, obtain mixed material;
Step 5, by the mixed material and the aqueous solution that are mixed to get by step 4 in mass ratio be 1:50 mixing, water bath sonicator, After ultrasonic 20min, at 170 DEG C after refluxing extraction 5h, filtering, obtain the first filtrate and the first filter residue, by the first filter residue with The ethanol solution that volumetric concentration is 85% is 1 in mass ratio:After 15 mixing, water bath sonicator, ultrasonic 30min, flowed back at 150 DEG C Extract after 4h, filtering obtains the second filtrate and the second filter residue, by the second filter residue with being pressed with volumetric concentration for 95% ethanol solution Mass ratio is 1:After 5 mixing, water bath sonicator, ultrasonic 30min, at 130 DEG C after refluxing extraction 4h, filtering obtains the 3rd filtrate, First filtrate, the second filtrate and the 3rd filtrate are mixed, obtain mixing filtrate;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, obtain water content≤ 10% solid, the powder that particle diameter is 200 μm is being ground to form by the solid, then used in outside line light irradiation 10min, that is, obtains described Raising quail immunologic function feed addictive.
Embodiment 3,
A kind of feed addictive for improving quail immunologic function is present embodiments provided, including:
Rhizoma Gastrodiae 15Kg, yncaria stem with hooks 10Kg, cassia seed 10Kg, stir-baked FRUCTUS GARDENIAE 12Kg, lophatherum gracile 10Kg, radix scutellariae 10Kg, capsule of weeping forsythia 12Kg, Lotus nut 6Kg, radix achyranthis bidentatae 10Kg, Ligusticum wallichii 15Kg, corydalis tuber 10Kg, caulis bambusae in taenian 7Kg and ostreae testa pulverata 2Kg.
This implementation discloses a kind of method for the feed addictive for preparing and improving quail immunologic function and comprised the following steps:
Step 1, by water and sodium bicarbonate according to mass ratio it is 50:1 mixing, as in water bath sonicator, water bath sonicator is revived Fetch water;
Step 2, the soda water that step 1 is prepared is heated to 45 DEG C, rhizoma Gastrodiae, hook are rinsed using 45 DEG C of soda water Rattan, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian, rinse 10min Afterwards, then with temperature for 60 DEG C of clear water rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, bosom are rinsed The root of bidentate achyranthes, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian 50min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus The sub- heart, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian and ostreae testa pulverata are as in drying unit, at 100 DEG C, dry aqueous to its Measure as 15%;
Using electron beam irradiation rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried and is irradiated, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, light The leaf of bamboo, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata grind to form the particle that particle diameter is 70 μm, The rhizoma Gastrodiae of particle, yncaria stem with hooks will be ground to form, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, prolonged Hu Suo, caulis bambusae in taenian and ostreae testa pulverata are well mixed in the case where rotating speed is 50rpm as in agitating device, obtain mixed material;
Step 5, by the mixed material and the aqueous solution that are mixed to get by step 4 in mass ratio be 1:50 mixing, water bath sonicator, After ultrasonic 20min, at 170 DEG C after refluxing extraction 5h, filtering, obtain the first filtrate and the first filter residue, by the first filter residue with The ethanol solution that volumetric concentration is 85% is 1 in mass ratio:After 15 mixing, water bath sonicator, ultrasonic 30min, flowed back at 150 DEG C Extract after 4h, filtering obtains the second filtrate and the second filter residue, by the second filter residue with being pressed with volumetric concentration for 95% ethanol solution Mass ratio is 1:After 5 mixing, water bath sonicator, ultrasonic 30min, at 130 DEG C after refluxing extraction 4h, filtering obtains the 3rd filtrate, First filtrate, the second filtrate and the 3rd filtrate are mixed, obtain mixing filtrate;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, obtain water content≤ 10% solid, the powder that particle diameter is 200 μm is being ground to form by the solid, then used in outside line light irradiation 10min, that is, obtains described Raising quail immunologic function feed addictive.
Embodiment 4,
A kind of feed addictive for improving quail immunologic function is present embodiments provided, including:
Rhizoma Gastrodiae 15Kg, yncaria stem with hooks 10Kg, cassia seed 10Kg, stir-baked FRUCTUS GARDENIAE 12Kg, lophatherum gracile 10Kg, radix scutellariae 10Kg, capsule of weeping forsythia 13Kg, Lotus nut 5Kg, radix achyranthis bidentatae 10Kg, Ligusticum wallichii 12Kg, corydalis tuber 10Kg, caulis bambusae in taenian 13Kg and ostreae testa pulverata 3Kg.
This implementation discloses a kind of method for the feed addictive for preparing and improving quail immunologic function and comprised the following steps:
Step 1, by water and sodium bicarbonate according to mass ratio it is 50:1 mixing, as in water bath sonicator, water bath sonicator is revived Fetch water;
Step 2, the soda water that step 1 is prepared is heated to 45 DEG C, rhizoma Gastrodiae, hook are rinsed using 45 DEG C of soda water Rattan, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian, rinse 10min Afterwards, then with temperature for 60 DEG C of clear water rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, bosom are rinsed The root of bidentate achyranthes, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian 50min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus The sub- heart, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian and ostreae testa pulverata are as in drying unit, at 100 DEG C, dry aqueous to its Measure as 15%;
Using electron beam irradiation rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried and is irradiated, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, light The leaf of bamboo, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata grind to form the particle that particle diameter is 70 μm, The rhizoma Gastrodiae of particle, yncaria stem with hooks will be ground to form, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, prolonged Hu Suo, caulis bambusae in taenian and ostreae testa pulverata are well mixed in the case where rotating speed is 50rpm as in agitating device, obtain mixed material;
Step 5, by the mixed material and the aqueous solution that are mixed to get by step 4 in mass ratio be 1:50 mixing, water bath sonicator, After ultrasonic 20min, at 170 DEG C after refluxing extraction 5h, filtering, obtain the first filtrate and the first filter residue, by the first filter residue with The ethanol solution that volumetric concentration is 85% is 1 in mass ratio:After 15 mixing, water bath sonicator, ultrasonic 30min, flowed back at 150 DEG C Extract after 4h, filtering obtains the second filtrate and the second filter residue, by the second filter residue with being pressed with volumetric concentration for 95% ethanol solution Mass ratio is 1:After 5 mixing, water bath sonicator, ultrasonic 30min, at 130 DEG C after refluxing extraction 4h, filtering obtains the 3rd filtrate, First filtrate, the second filtrate and the 3rd filtrate are mixed, obtain mixing filtrate;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, obtain water content≤ 10% solid, the powder that particle diameter is 200 μm is being ground to form by the solid, then used in outside line light irradiation 10min, that is, obtains described Raising quail immunologic function feed addictive.
Embodiment 5,
A kind of feed addictive for improving quail immunologic function is present embodiments provided, including:
Rhizoma Gastrodiae 11Kg, yncaria stem with hooks 14Kg, cassia seed 7Kg, stir-baked FRUCTUS GARDENIAE 135Kg, lophatherum gracile 8Kg, radix scutellariae 12Kg, capsule of weeping forsythia 11Kg, Lotus nut 7Kg, radix achyranthis bidentatae 9Kg, Ligusticum wallichii 11Kg, corydalis tuber 9Kg, caulis bambusae in taenian 8Kg and ostreae testa pulverata 4Kg.
This implementation discloses a kind of method for the feed addictive for preparing and improving quail immunologic function and comprised the following steps:
Step 1, by water and sodium bicarbonate according to mass ratio it is 50:1 mixing, as in water bath sonicator, water bath sonicator is revived Fetch water;
Step 2, the soda water that step 1 is prepared is heated to 45 DEG C, rhizoma Gastrodiae, hook are rinsed using 45 DEG C of soda water Rattan, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian, rinse 10min Afterwards, then with temperature for 60 DEG C of clear water rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, bosom are rinsed The root of bidentate achyranthes, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian 50min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus The sub- heart, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian and ostreae testa pulverata are as in drying unit, at 100 DEG C, dry aqueous to its Measure as 15%;
Using electron beam irradiation rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried and is irradiated, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, light The leaf of bamboo, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata grind to form the particle that particle diameter is 70 μm, The rhizoma Gastrodiae of particle, yncaria stem with hooks will be ground to form, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, prolonged Hu Suo, caulis bambusae in taenian and ostreae testa pulverata are well mixed in the case where rotating speed is 50rpm as in agitating device, obtain mixed material;
Step 5, by the mixed material and the aqueous solution that are mixed to get by step 4 in mass ratio be 1:50 mixing, water bath sonicator, After ultrasonic 20min, at 170 DEG C after refluxing extraction 5h, filtering, obtain the first filtrate and the first filter residue, by the first filter residue with The ethanol solution that volumetric concentration is 85% is 1 in mass ratio:After 15 mixing, water bath sonicator, ultrasonic 30min, flowed back at 150 DEG C Extract after 4h, filtering obtains the second filtrate and the second filter residue, by the second filter residue with being pressed with volumetric concentration for 95% ethanol solution Mass ratio is 1:After 5 mixing, water bath sonicator, ultrasonic 30min, at 130 DEG C after refluxing extraction 4h, filtering obtains the 3rd filtrate, First filtrate, the second filtrate and the 3rd filtrate are mixed, obtain mixing filtrate;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, obtain water content≤ 10% solid, the powder that particle diameter is 200 μm is being ground to form by the solid, then used in outside line light irradiation 10min, that is, obtains described Raising quail immunologic function feed addictive.
Embodiment 6,
A kind of feed addictive for improving quail immunologic function is present embodiments provided, including:
Rhizoma Gastrodiae 13Kg, yncaria stem with hooks 11Kg, cassia seed 11Kg, stir-baked FRUCTUS GARDENIAE 11Kg, lophatherum gracile 11Kg, radix scutellariae 11Kg, capsule of weeping forsythia 11Kg, Lotus nut 8Kg, radix achyranthis bidentatae 11Kg, Ligusticum wallichii 11Kg, corydalis tuber 11Kg, caulis bambusae in taenian 8Kg and ostreae testa pulverata 4Kg.
This implementation discloses a kind of method for the feed addictive for preparing and improving quail immunologic function and comprised the following steps:
Step 1, by water and sodium bicarbonate according to mass ratio it is 50:1 mixing, as in water bath sonicator, water bath sonicator is revived Fetch water;
Step 2, the soda water that step 1 is prepared is heated to 45 DEG C, rhizoma Gastrodiae, hook are rinsed using 45 DEG C of soda water Rattan, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian, rinse 10min Afterwards, then with temperature for 60 DEG C of clear water rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, bosom are rinsed The root of bidentate achyranthes, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian 50min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus The sub- heart, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian and ostreae testa pulverata are as in drying unit, at 100 DEG C, dry aqueous to its Measure as 15%;
Using electron beam irradiation rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried and is irradiated, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, light The leaf of bamboo, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata grind to form the particle that particle diameter is 70 μm, The rhizoma Gastrodiae of particle, yncaria stem with hooks will be ground to form, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, prolonged Hu Suo, caulis bambusae in taenian and ostreae testa pulverata are well mixed in the case where rotating speed is 50rpm as in agitating device, obtain mixed material;
Step 5, by the mixed material and the aqueous solution that are mixed to get by step 4 in mass ratio be 1:50 mixing, water bath sonicator, After ultrasonic 20min, at 170 DEG C after refluxing extraction 5h, filtering, obtain the first filtrate and the first filter residue, by the first filter residue with The ethanol solution that volumetric concentration is 85% is 1 in mass ratio:After 15 mixing, water bath sonicator, ultrasonic 30min, flowed back at 150 DEG C Extract after 4h, filtering obtains the second filtrate and the second filter residue, by the second filter residue with being pressed with volumetric concentration for 95% ethanol solution Mass ratio is 1:After 5 mixing, water bath sonicator, ultrasonic 30min, at 130 DEG C after refluxing extraction 4h, filtering obtains the 3rd filtrate, First filtrate, the second filtrate and the 3rd filtrate are mixed, obtain mixing filtrate;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, obtain water content≤ 10% solid, the powder that particle diameter is 200 μm is being ground to form by the solid, then used in outside line light irradiation 10min, that is, obtains described Raising quail immunologic function feed addictive.
Embodiment 7,
A kind of feed addictive for improving quail immunologic function is present embodiments provided, including:
Rhizoma Gastrodiae 15Kg, yncaria stem with hooks 10Kg, cassia seed 10Kg, stir-baked FRUCTUS GARDENIAE 14Kg, lophatherum gracile 13Kg, radix scutellariae 13Kg, capsule of weeping forsythia 11Kg, Lotus nut 6Kg, radix achyranthis bidentatae 14Kg, Ligusticum wallichii 12Kg, corydalis tuber 13Kg, caulis bambusae in taenian 9Kg and ostreae testa pulverata 3Kg.
This implementation discloses a kind of method for the feed addictive for preparing and improving quail immunologic function and comprised the following steps:
Step 1, by water and sodium bicarbonate according to mass ratio it is 50:1 mixing, as in water bath sonicator, water bath sonicator is revived Fetch water;
Step 2, the soda water that step 1 is prepared is heated to 45 DEG C, rhizoma Gastrodiae, hook are rinsed using 45 DEG C of soda water Rattan, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian, rinse 10min Afterwards, then with temperature for 60 DEG C of clear water rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, bosom are rinsed The root of bidentate achyranthes, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian 50min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus The sub- heart, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian and ostreae testa pulverata are as in drying unit, at 100 DEG C, dry aqueous to its Measure as 15%;
Using electron beam irradiation rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried and is irradiated, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, light The leaf of bamboo, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata grind to form the particle that particle diameter is 70 μm, The rhizoma Gastrodiae of particle, yncaria stem with hooks will be ground to form, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, prolonged Hu Suo, caulis bambusae in taenian and ostreae testa pulverata are well mixed in the case where rotating speed is 50rpm as in agitating device, obtain mixed material;
Step 5, by the mixed material and the aqueous solution that are mixed to get by step 4 in mass ratio be 1:50 mixing, water bath sonicator, After ultrasonic 20min, at 170 DEG C after refluxing extraction 5h, filtering, obtain the first filtrate and the first filter residue, by the first filter residue with The ethanol solution that volumetric concentration is 85% is 1 in mass ratio:After 15 mixing, water bath sonicator, ultrasonic 30min, flowed back at 150 DEG C Extract after 4h, filtering obtains the second filtrate and the second filter residue, by the second filter residue with being pressed with volumetric concentration for 95% ethanol solution Mass ratio is 1:After 5 mixing, water bath sonicator, ultrasonic 30min, at 130 DEG C after refluxing extraction 4h, filtering obtains the 3rd filtrate, First filtrate, the second filtrate and the 3rd filtrate are mixed, obtain mixing filtrate;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, obtain water content≤ 10% solid, the powder that particle diameter is 200 μm is being ground to form by the solid, then used in outside line light irradiation 10min, that is, obtains described Raising quail immunologic function feed addictive
Compliance test result example:
Feed formulation:By embodiment 1-5 prepare raising quail immunologic function feed addictive respectively with quail feed It is 1 according to mass ratio:77 are mixed to get addition feed, obtain the feeding feed that reference numeral is 1-5;
Subjects:The healthy disease-free squealer of 120 broken shells 3 days;
The foundation of test group and blank group:By 120 subjects, in the form of every group 20, it is divided into test group 1, examination Test group 2, test group 3, test group 4, test group 5 and blank group;
The feeding feed that the feeding of test group 1 numbering is 1, daily feeding 5 times, feeding 30 days;The feeding of test group 2 numbering is 2 Feeding feed, daily feeding 5 times, feeding 30 days;The feeding feed that the feeding of test group 3 numbering is 3, daily feeding 5 times, feeding 30 days;The feeding feed that the feeding of test group 4 numbering is 4, daily feeding 5 times, feeding 30 days;The feeding of test group 5 numbering be 5 feed Eat feed, daily feeding 5 times, feeding 30 days;Blank group feeding is not added with the feed of additive of the present invention, daily feeding 5 times, feeding 30 days.
The survival rate of squealer is detected after 30 days, one is the results are shown in Table.
Table one
Test group 1 Test group 2 Test group 3 Test group 4 Test group 5 Blank group
Survival rate 93% 95% 95% 94% 94% 81%
As can be seen from Table I, feed addition of the feeding added with the embodiment 1-5 raising quail immunologic functions prepared The survival rate of the squealer of the feeding feed of agent is apparently higher than un-added.
Although embodiment of the present invention is disclosed as above, it is not restricted in specification and embodiment listed With it can be applied to various suitable the field of the invention completely, can be easily for those skilled in the art Other modification is realized, therefore under the universal limited without departing substantially from claim and equivalency range, the present invention is not limited In specific details.

Claims (6)

1. a kind of preparation method for the feed addictive for improving quail immunologic function, it is characterised in that comprise the following steps:
It includes the raw material of following parts by weight:
10-20 parts of rhizoma Gastrodiae, 5-15 parts of yncaria stem with hooks, 5-15 parts of cassia seed, 10-15 parts of stir-baked FRUCTUS GARDENIAE, 5-15 parts of lophatherum gracile, radix scutellariae 5-15 Part, 10-15 parts of the capsule of weeping forsythia, 1-10 parts of lotus nut, 5-15 parts of radix achyranthis bidentatae, 10-15 parts of Ligusticum wallichii, 5-15 parts of corydalis tuber, 5-10 parts of caulis bambusae in taenian With 1-5 parts of ostreae testa pulverata;
Step 1, by water and sodium bicarbonate according to mass ratio it is 50:1 mixing, as in water bath sonicator, water bath sonicator obtains soda Water;
Step 2, the soda water that step 1 is prepared is heated to 45 DEG C, rhizoma Gastrodiae, yncaria stem with hooks, certainly are rinsed using 45 DEG C of soda water Pine torch, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian, are rinsed after 10min, then use Temperature rinses rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, river for 60 DEG C of clear water Rhizome of chuanxiong, corydalis tuber and caulis bambusae in taenian 50min;
Step 3, the rhizoma Gastrodiae by after step 2 is rinsed, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, Radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber and caulis bambusae in taenian and ostreae testa pulverata are as in drying unit, at 100 DEG C, and drying to its water content is 15%;
Using electron beam irradiation rhizoma Gastrodiae, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, river Rhizome of chuanxiong, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata;
Step 4, using lapping device by the rhizoma Gastrodiae after step 3 is dried and is irradiated, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, henon bamboo Leaf, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, corydalis tuber, caulis bambusae in taenian and ostreae testa pulverata grind to form the particle that particle diameter is 70 μm, will Grind to form the rhizoma Gastrodiae of particle, yncaria stem with hooks, cassia seed, stir-baked FRUCTUS GARDENIAE, lophatherum gracile, radix scutellariae, the capsule of weeping forsythia, lotus nut, radix achyranthis bidentatae, Ligusticum wallichii, prolong recklessly Rope, caulis bambusae in taenian and ostreae testa pulverata are well mixed in the case where rotating speed is 50rpm as in agitating device, obtain mixed material;
Step 5, by the mixed material and the aqueous solution that are mixed to get by step 4 in mass ratio be 1:50 mixing, water bath sonicator, ultrasound After 20min, at 170 DEG C after refluxing extraction 5h, filtering obtains the first filtrate and the first filter residue, by the first filter residue and and volume The ethanol solution that concentration is 85% is 1 in mass ratio:After 15 mixing, water bath sonicator, ultrasonic 30min, the refluxing extraction at 150 DEG C After 4h, filtering obtains the second filtrate and the second filter residue, by the second filter residue with pressing quality with volumetric concentration for 95% ethanol solution Than for 1:After 5 mixing, water bath sonicator, ultrasonic 30min, at 130 DEG C after refluxing extraction 4h, filtering obtains the 3rd filtrate, by institute The first filtrate, the second filtrate and the mixing of the 3rd filtrate are stated, obtains mixing filtrate;
Step 6, at 100 DEG C, the ethanol in the mixing filtrate that step 5 is obtained is evaporated, and obtains water content≤10% Solid, is grinding to form the powder that particle diameter is 200 μm, then used in outside line light irradiation 10min, that is, obtain described raising by the solid The feed addictive of quail immunologic function.
2. the preparation method of the feed addictive of quail immunologic function is improved as claimed in claim 1, it is characterised in that including The raw material of following parts by weight:
10 parts of rhizoma Gastrodiae, 5 parts of yncaria stem with hooks, 15 parts of cassia seed, 15 parts of stir-baked FRUCTUS GARDENIAE, 5 parts of lophatherum gracile, 15 parts of radix scutellariae, 10 parts of the capsule of weeping forsythia, lotus nut 1 part of 10 parts, 15 parts of radix achyranthis bidentatae, 15 parts of Ligusticum wallichii, 5 parts of corydalis tuber, 5 parts of caulis bambusae in taenian and ostreae testa pulverata.
3. the preparation method of the feed addictive of quail immunologic function is improved as claimed in claim 1, it is characterised in that including The raw material of following parts by weight:
20 parts of rhizoma Gastrodiae, 15 parts of yncaria stem with hooks, 5 parts of cassia seed, 10 parts of stir-baked FRUCTUS GARDENIAE, 15 parts of lophatherum gracile, 5 parts of radix scutellariae, 15 parts of the capsule of weeping forsythia, lotus nut 5 parts of 1 part, 5 parts of radix achyranthis bidentatae, 10 parts of Ligusticum wallichii, 15 parts of corydalis tuber, 10 parts of caulis bambusae in taenian and ostreae testa pulverata.
4. the preparation method of the feed addictive of quail immunologic function is improved as claimed in claim 1, it is characterised in that including The raw material of following parts by weight:
15 parts of rhizoma Gastrodiae, 10 parts of yncaria stem with hooks, 10 parts of cassia seed, 12 parts of stir-baked FRUCTUS GARDENIAE, 10 parts of lophatherum gracile, 10 parts of radix scutellariae, 12 parts of the capsule of weeping forsythia, lotus seeds 2 parts of 6 parts of the heart, 10 parts of radix achyranthis bidentatae, 15 parts of Ligusticum wallichii, 10 parts of corydalis tuber, 7 parts of caulis bambusae in taenian and ostreae testa pulverata.
5. the preparation method of the feed addictive of quail immunologic function is improved as claimed in claim 1, it is characterised in that electronics The irradiation dose of beam is 8Gy.
6. the preparation method of the feed addictive of quail immunologic function is improved as claimed in claim 1, it is characterised in that electronics The exposure time of beam is 6min.
CN201710246692.1A 2017-04-16 2017-04-16 Improve the preparation method of the feed addictive of quail immunologic function Pending CN107183397A (en)

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CN103652442A (en) * 2013-12-04 2014-03-26 浙江大学 Feed additive for improving growth immune function of broilers, preparation method and application
CN104147586A (en) * 2014-09-11 2014-11-19 东北农业大学 Chinese herbal medicine composition and fodder for preventing and treating cold irritable enteritis of quails
CN104509686A (en) * 2013-09-27 2015-04-15 任白宝 Feed capable of strengthening quail immunity
CN105533253A (en) * 2016-01-05 2016-05-04 闫冷 Feed additive for treating quail disease

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CN102450515A (en) * 2010-12-06 2012-05-16 山东六和集团有限公司 Laying hen feed and traditional Chinese medicine feed additive used by same
CN102450523A (en) * 2010-12-06 2012-05-16 山东六和集团有限公司 Feed for meat ducks and traditional Chinese medicine additive thereof
CN102450517A (en) * 2010-12-06 2012-05-16 山东六和集团有限公司 Broiler feed and traditional Chinese medicine additive used by same
CN104509686A (en) * 2013-09-27 2015-04-15 任白宝 Feed capable of strengthening quail immunity
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