CN107156302A - The baby formula milk powder and preparation method of a kind of creaminess fat ball film - Google Patents
The baby formula milk powder and preparation method of a kind of creaminess fat ball film Download PDFInfo
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- CN107156302A CN107156302A CN201710247099.9A CN201710247099A CN107156302A CN 107156302 A CN107156302 A CN 107156302A CN 201710247099 A CN201710247099 A CN 201710247099A CN 107156302 A CN107156302 A CN 107156302A
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- 125000005457 triglyceride group Chemical group 0.000 description 1
- VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/16—Agglomerating or granulating milk powder; Making instant milk powder; Products obtained thereby
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
- A23C9/1526—Amino acids; Peptides; Protein hydrolysates; Nucleic acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
- A23C9/1528—Fatty acids; Mono- or diglycerides; Petroleum jelly; Paraffine; Phospholipids; Derivatives thereof
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Dairy Products (AREA)
Abstract
Description
技术领域technical field
本发明属于食品技术领域，涉及婴儿配方奶粉及制备方法。The invention belongs to the technical field of food and relates to infant formula milk powder and a preparation method.
背景技术Background technique
母乳是婴幼儿最理想的天然食物，母乳中丰富的营养物质为婴幼儿的生长发育提供了能量和营养需求。脂肪是母乳主要成分之一，含量约为3%-5%，为婴儿生长发育提供50%以上的能量和多种脂肪酸，主要以脂肪球的形式分散在乳中，核心为甘油三酯，外部包裹由极性脂和蛋白质等组成的三层生物膜，称为乳脂肪球膜（MFGM）。MFGM上存在的许多膜蛋白，如嗜乳脂蛋、黄嘌呤氧化、还原酶和乳脂肪球表面生长因子8已被证实具有抗癌作用。作为乳脂中最重要组分的磷脂，其中60%-70%都在MFGM上，主要有神经鞘磷脂、卵磷脂等。鞘磷脂对于婴幼儿早期大脑和神经发育具有重要意义，卵磷脂是体内胆碱的储存形式。关于乳脂肪球膜健康效应的研究表明：乳脂肪球膜可以提高婴儿的认知能力；改善代谢模式；具有抗感染作用。通过对母乳和其他哺乳动物乳如牛乳脂质进行比较发现它们的MFGM都是从分泌细胞膜衍生出来的，在组成上相似。因此除人乳外的其他哺乳动物乳MFGM在一定程度上可以替代人乳MFGM。Breast milk is the most ideal natural food for infants and young children. The rich nutrients in breast milk provide energy and nutritional needs for the growth and development of infants and young children. Fat is one of the main components of breast milk, with a content of about 3%-5%. It provides more than 50% of the energy and a variety of fatty acids for the growth and development of the baby. It is mainly dispersed in the milk in the form of fat globules. The core is triglyceride, and the outer A three-layer biological membrane consisting of polar lipids and proteins is called milk fat globule membrane (MFGM). Many membrane proteins present on MFGM, such as butterophilus, xanthine oxidizer, reductase, and milk fat globule surface growth factor 8, have been shown to have anticancer effects. As the most important component of milk fat, phospholipids, 60%-70% of which are on MFGM, mainly include sphingomyelin and lecithin. Sphingomyelin is important for early brain and neurodevelopment in infants and young children, and lecithin is the storage form of choline in the body. Studies on the health effects of milk fat globule membranes have shown that: milk fat globule membranes can improve cognitive abilities of infants; improve metabolic patterns; and have anti-infective effects. By comparing human milk with other mammalian milk such as bovine milk lipids, it is found that their MFGM are derived from secretory cell membranes and are similar in composition. Therefore, other mammalian milk MFGM can replace human milk MFGM to a certain extent.
当母乳不能满足需求时，一般选择婴幼儿配方奶粉作为营养补充食品。目前大部分的配方奶粉来源于牛乳，婴幼儿配方粉的基本原则是调节牛乳成分，使其最大程度上与人乳相似。但在脂肪组成上大多数配方奶粉没有使用带有乳脂球膜的牛乳脂肪，而使用了多种植物油配方来模拟母乳脂肪含量及脂肪酸构成，缺少MFGM相关组分。近年来，对MFGM功能的研究已成为热点，MFGM在婴儿生长发育过程中所起到的作用越来越受到重视。关于食用普通奶粉和添加MFGM成分奶粉婴儿的对比研究中发现，在行为方式、认知能力及抗感染能力上，添加了MFGM成分的配方奶粉喂养儿与母乳喂养儿更为相似。因此，为弥补市场上关于不含MFGM成分奶粉的缺失，本研究通过适当的方法对乳脂肪球膜进行完整的提取，使其原有成分和结构受到最小程度的破坏，进而将其添加到配方奶粉中用于减小配方奶粉与母乳之间的差异。When breast milk cannot meet the demand, infant formula milk powder is generally selected as a nutritional supplement. At present, most formula milk powder comes from cow milk. The basic principle of infant formula powder is to adjust the composition of cow milk to make it similar to human milk to the greatest extent. However, in terms of fat composition, most formula milk powder does not use milk fat with milk fat globules, but uses a variety of vegetable oil formulas to simulate breast milk fat content and fatty acid composition, lacking MFGM related components. In recent years, the research on the function of MFGM has become a hot spot, and the role of MFGM in the growth and development of infants has been paid more and more attention. In a comparative study of infants who consumed ordinary milk powder and infants with MFGM-added formula, it was found that formula-fed infants with MFGM-added ingredients were more similar to breast-fed infants in terms of behavior, cognitive ability, and anti-infection ability. Therefore, in order to make up for the lack of MFGM-free milk powder on the market, this study used an appropriate method to completely extract the milk fat globule membrane, so that its original composition and structure were minimally damaged, and then added it to the formula Used in powdered milk to reduce the difference between formula and breast milk.
发明内容Contents of the invention
为解决上述问题，本发明提供了一种含乳脂肪球膜的婴儿配方奶粉及制备方法。In order to solve the above problems, the invention provides an infant formula milk powder containing milk fat globule membrane and a preparation method thereof.
本发明是通过以下技术方案实现的。The present invention is achieved through the following technical solutions.
本发明所述的一种含乳脂肪球膜的婴儿配方奶粉，包括以下组分：脱脂乳粉10-45%，脱盐乳清粉15-40%，浓缩乳清蛋白粉1-8%，乳糖5-15%，植物油10-25%，矿物质0.1-0.56%，维生素0.02-0.5%，乳脂肪球膜0.01-1.5%，其他营养素0.1-0.57%； 其中，所述的其他营养素包括碳酸钙、氯化钙、牛磺酸和胆碱中的一种或多种；所述百分比为各组分占婴儿配方奶粉原料的质量百分比。An infant formula milk powder containing milk fat globule membrane according to the present invention comprises the following components: 10-45% of skimmed milk powder, 15-40% of desalted whey powder, 1-8% of concentrated whey protein powder, lactose 5-15%, vegetable oil 10-25%, minerals 0.1-0.56%, vitamins 0.02-0.5%, milk fat globule membrane 0.01-1.5%, other nutrients 0.1-0.57%; wherein, the other nutrients include calcium carbonate One or more of , calcium chloride, taurine and choline; said percentage is the mass percentage of each component in the raw material of infant formula milk powder.
优选地，脱脂乳粉15-35%，脱盐乳清粉20-35%，浓缩乳清蛋白粉1-6%，乳糖8-15%，植物油10-20%，矿物质0.15-0.5%，维生素0.03-0.35%，乳脂肪球膜0.03-0.85%，其他营养素0.2-0.45%；其中，所述的其他营养素包括碳酸钙、氯化钙、牛磺酸和胆碱中的一种或多种；所述百分比为各组分占婴儿配方奶粉原料的质量百分比。Preferably, skimmed milk powder 15-35%, desalted whey powder 20-35%, concentrated whey protein powder 1-6%, lactose 8-15%, vegetable oil 10-20%, minerals 0.15-0.5%, vitamin 0.03-0.35%, milk fat globule membrane 0.03-0.85%, other nutrients 0.2-0.45%; wherein, the other nutrients include one or more of calcium carbonate, calcium chloride, taurine and choline; The percentages are the mass percentages of each component in the infant formula raw material.
优选地，脱脂乳粉15-30%，脱盐乳清粉20-30%，浓缩乳清蛋白粉2-6%，乳糖8-12%，植物油5-15%，矿物质0.1-0.45%，维生素0.05-0.2%，乳脂肪球膜0.05-0.7%，其他营养素0.25-0.45%；其中，所述的其他营养素包括碳酸钙、氯化钙、牛磺酸和胆碱中的一种或多种；所述百分比为各组分占婴儿配方奶粉原料的质量百分比。Preferably, skimmed milk powder 15-30%, desalted whey powder 20-30%, concentrated whey protein powder 2-6%, lactose 8-12%, vegetable oil 5-15%, minerals 0.1-0.45%, vitamins 0.05-0.2%, milk fat globule membrane 0.05-0.7%, other nutrients 0.25-0.45%; wherein, the other nutrients include one or more of calcium carbonate, calcium chloride, taurine and choline; The percentages are the mass percentages of each component in the infant formula raw material.
优选地，所述脱盐乳清粉为D70和/或D90。Preferably, the desalted whey powder is D70 and/or D90.
优选地，所述乳糖为无水乳糖。Preferably, the lactose is anhydrous lactose.
本发明所述碳酸钙的添加量为0.15-0.35%，所述氯化钙的添加量为0.1-0.2%，所述牛磺酸的添加量为0.01-0.05%，所述胆碱的添加量为0.04-0.08%，所述百分比为各组分占婴儿配方奶粉原料的质量百分比。The addition amount of calcium carbonate described in the present invention is 0.15-0.35%, the addition amount of described calcium chloride is 0.1-0.2%, the addition amount of described taurine is 0.01-0.05%, the addition amount of described choline It is 0.04-0.08%, and the percentage is the mass percentage of each component in the raw material of infant formula milk powder.
本发明所述乳脂肪球膜，是来自奶牛乳、水牛乳、牦牛乳、山羊乳、绵羊乳、猪乳、马乳、驴乳等的一种；所述乳脂肪球膜的添加量为0.01-1.5%。The milk fat globule film of the present invention is a kind of from cow milk, buffalo milk, yak milk, goat milk, sheep milk, pig milk, horse milk, donkey milk, etc.; the addition amount of the milk fat globule film is 0.01 -1.5%.
本发明所述乳脂肪球膜，是采用经典方法提取的，最大程度保证乳脂肪球膜完整性不受破坏。The milk fat globule membrane of the present invention is extracted by a classical method, which ensures that the integrity of the milk fat globule membrane is not damaged to the greatest extent.
本发明所述的一种含乳脂肪球膜婴儿配方奶的制备方法，按如下步骤。A method for preparing milk fat globule membrane-containing infant formula according to the present invention comprises the following steps.
1）按经典提取方法从原料乳中提取乳脂肪球膜。1) Extract the milk fat globule membrane from the raw milk according to the classical extraction method.
2）将脱脂乳粉、脱盐乳清粉、浓缩乳清蛋白粉、乳糖、矿物质、维生素混合，得料液A。2) Mix skimmed milk powder, desalted whey powder, concentrated whey protein powder, lactose, minerals, and vitamins to obtain feed liquid A.
3）将料液A与乳脂肪球膜、植物油和其他营养素混合，得料液B。3) Mix feed liquid A with milk fat globule film, vegetable oil and other nutrients to obtain feed liquid B.
4）采用高速分散机将料液B在8000-12000 r/min分散50-120 s。4) Use a high-speed disperser to disperse the liquid B at 8000-12000 r/min for 50-120 s.
5）采用高压均质机、高压动态微射流、胶体磨中的一种或者多种在10-70MPa 下对步骤4）所得料液进行均质。5) Use one or more of high-pressure homogenizer, high-pressure dynamic micro-jet, and colloid mill to homogenize the feed liquid obtained in step 4) at 10-70MPa.
6）将步骤4）所得样品采用适当的干燥方法如喷雾干燥和冷冻干燥等进行干燥，得到粉状产品，灭菌，真空包装。6) The sample obtained in step 4) is dried by an appropriate drying method such as spray drying and freeze drying to obtain a powder product, sterilized, and vacuum-packed.
本发明婴儿配方奶粉中的乳脂肪球膜，含有多种具有生理功能的膜蛋白，主要有黄嘌呤氧化还原酶、嗜乳脂蛋白、乳凝集素和黏液素等。黄嘌呤氧化还原酶已经证实在乳腺的发育、肠道的抗菌和组织损伤中具有一定的作用；嗜乳脂蛋白是一种与脂肪滴相关的蛋白质是免疫球蛋白家族中的一员；乳凝集素又称为乳脂肪球表皮生长因子是具有免疫源性的亲脂性糖蛋白；黏液素是黏膜物理防御的重要组成成分可能与上皮感染和炎症反应有关。除此之外，乳脂肪球膜上还含有多种极性脂如卵磷脂、鞘磷脂等。卵磷脂是体内胆碱的储存形式；鞘磷脂除了对婴幼儿大脑神经发育和认知能力有重要意义外，还被证实具有抗癌功能。研究表明，在配方奶粉中添加乳脂肪球膜对婴幼儿发育初期神经和免疫系统的发展有积极作用，而这一直是当前婴幼儿配方奶粉所缺少的。除此之外，乳脂肪球膜能提高婴幼儿的认知发展，达到与母乳喂养的婴幼儿相似的认知发育水平，并且降低中耳炎的感染比率，其成分及功能的发现，对婴儿配方食品进一步模拟母乳、提高喂养效果具有重要意义。在与母乳为期12个月的试验对比中，这种有添加乳脂肪球膜奶粉的婴幼儿喂养成长率与母乳喂养效果非常相似。The milk fat globule membrane in the infant formula milk powder of the present invention contains a variety of membrane proteins with physiological functions, mainly including xanthine oxidoreductase, butterophilic protein, lactoagglutinin, mucin and the like. Xanthine oxidoreductase has been confirmed to have a certain role in mammary gland development, intestinal antibacterial and tissue damage; butterophilin is a protein associated with fat droplets and is a member of the immunoglobulin family; lactagglutinin Also known as milk fat globules, epidermal growth factor is an immunogenic lipophilic glycoprotein; mucin is an important component of mucosal physical defense and may be related to epithelial infection and inflammatory responses. In addition, the milk fat globule membrane also contains a variety of polar lipids such as lecithin, sphingomyelin and so on. Lecithin is the storage form of choline in the body; sphingomyelin is not only important for infant brain neurodevelopment and cognitive ability, but also has anti-cancer function. Research has shown that the addition of milk fat globule membranes to formula has a positive effect on the development of the nervous and immune systems in early infant development, which has been lacking in current infant formulas. In addition, the milk fat globule membrane can improve the cognitive development of infants and young children, reach a level of cognitive development similar to that of breastfed infants, and reduce the infection rate of otitis media. It is of great significance to further simulate breast milk and improve the feeding effect. In a 12-month trial compared with breast milk, infants and young children fed this formula with added milk fat globule membranes had very similar growth rates to breastfeeding.
具体实施方式detailed description
下面结合实例对本发明作进一步说明。Below in conjunction with example the present invention will be further described.
实施例1。Example 1.
本实施实例婴幼儿配方奶粉配方如下：脱脂乳粉35%，脱盐乳清粉30%，浓缩乳清蛋白粉7%，乳糖12%，植物油15%，矿物质0.18%，维生素0.15%，乳脂肪球膜0.3%，碳酸钙0.2%，氯化钙0.15%，牛磺酸0.02%。In this implementation example, the formula of infant formula milk powder is as follows: 35% skimmed milk powder, 30% desalted whey powder, 7% concentrated whey protein powder, 12% lactose, 15% vegetable oil, 0.18% mineral matter, 0.15% vitamin, milk fat Membrane 0.3%, Calcium Carbonate 0.2%, Calcium Chloride 0.15%, Taurine 0.02%.
制备：1）按经典的提取方法从原料乳中提取乳脂肪球膜。Preparation: 1) Extract the milk fat globule membrane from the raw milk according to the classic extraction method.
2）将脱脂乳粉、脱盐乳清粉、浓缩乳清蛋白粉、乳糖、矿物质、维生素混合，得料液A。2) Mix skimmed milk powder, desalted whey powder, concentrated whey protein powder, lactose, minerals, and vitamins to obtain feed liquid A.
3）将料液A与乳脂肪球膜、植物油和其他营养素混合，得料液B。3) Mix feed liquid A with milk fat globule film, vegetable oil and other nutrients to obtain feed liquid B.
4）采用高速分散机将料液B在8000-12000 r/min分散50-120 s。4) Use a high-speed disperser to disperse the liquid B at 8000-12000 r/min for 50-120 s.
5）采用用高压均质机、高压动态微射流、胶体磨中的一种或者多种在10-70 MPa下对步骤4）所得料液进行均质。5) Use one or more of high-pressure homogenizer, high-pressure dynamic micro-jet, and colloid mill to homogenize the feed liquid obtained in step 4) at 10-70 MPa.
6）将步骤4）所得样品采用适当的干燥方法如喷雾干燥和冷冻干燥等进行干燥，得到粉状产品，灭菌，真空包装。 6) The sample obtained in step 4) is dried by an appropriate drying method such as spray drying and freeze drying to obtain a powder product, sterilized, and vacuum-packed.
实施例2。Example 2.
本实施实例婴幼儿配方奶粉配方如下：脱脂乳粉35%，脱盐乳清粉30%，浓缩乳清蛋白粉7%，乳糖12%，植物油15%，矿物质0.18%，维生素0.15%，乳脂肪球膜0.2%，碳酸钙0.2%，氯化钙0.17%，牛磺酸0.04%，胆碱0.06%。In this implementation example, the formula of infant formula milk powder is as follows: 35% skimmed milk powder, 30% desalted whey powder, 7% concentrated whey protein powder, 12% lactose, 15% vegetable oil, 0.18% mineral matter, 0.15% vitamin, milk fat Membrane 0.2%, Calcium Carbonate 0.2%, Calcium Chloride 0.17%, Taurine 0.04%, Choline 0.06%.
制备：1）按经典的提取方法从原料乳中提取乳脂肪球膜。Preparation: 1) Extract the milk fat globule membrane from the raw milk according to the classic extraction method.
2）将脱脂乳粉、脱盐乳清粉、浓缩乳清蛋白粉、乳糖、矿物质、维生素混合，得料液A。2) Mix skimmed milk powder, desalted whey powder, concentrated whey protein powder, lactose, minerals, and vitamins to obtain feed liquid A.
3）将料液A与乳脂肪球膜、植物油和其他营养素混合，得料液B。3) Mix feed liquid A with milk fat globule film, vegetable oil and other nutrients to obtain feed liquid B.
4）采用高速分散机将料液B在8000-12000 r/min分散50-120 s。 4) Use a high-speed disperser to disperse the liquid B at 8000-12000 r/min for 50-120 s.
5）采用用高压均质机、高压动态微射流、胶体磨中的一种或者多种在10-70 MPa下对步骤4）所得料液进行均质。 5) Use one or more of high-pressure homogenizer, high-pressure dynamic micro-jet, and colloid mill to homogenize the feed liquid obtained in step 4) at 10-70 MPa.
6）将步骤4）所得样品采用适当的干燥方法如喷雾干燥和冷冻干燥等进行干燥，得到粉状产品，灭菌，真空包装。 6) The sample obtained in step 4) is dried by an appropriate drying method such as spray drying and freeze drying to obtain a powder product, sterilized, and vacuum-packed.
实施例3。Example 3.
本实施实例婴幼儿配方奶粉配方如下：脱脂乳粉35%，脱盐乳清粉30%，浓缩乳清蛋白粉7%，乳糖12%，植物油15%，矿物质0.38%，维生素0.15%，乳脂肪球膜0.1%，碳酸钙0.2%，氯化钙0.15%，牛磺酸0.02%。In this implementation example, the formula of infant formula milk powder is as follows: 35% skimmed milk powder, 30% desalted whey powder, 7% concentrated whey protein powder, 12% lactose, 15% vegetable oil, 0.38% mineral matter, 0.15% vitamin, milk fat Membrane 0.1%, Calcium Carbonate 0.2%, Calcium Chloride 0.15%, Taurine 0.02%.
制备：1）按经典的提取方法从原料乳中提取乳脂肪球膜。Preparation: 1) Extract the milk fat globule membrane from the raw milk according to the classic extraction method.
2）将脱脂乳粉、脱盐乳清粉、浓缩乳清蛋白粉、乳糖、矿物质、维生素混合，得料液A。2) Mix skimmed milk powder, desalted whey powder, concentrated whey protein powder, lactose, minerals, and vitamins to obtain feed liquid A.
3）将料液A与乳脂肪球膜、植物油和其他营养素混合，得料液B。3) Mix feed liquid A with milk fat globule film, vegetable oil and other nutrients to obtain feed liquid B.
4）采用高速分散机将料液B在8000-12000 r/min分散50-120 s。4) Use a high-speed disperser to disperse the liquid B at 8000-12000 r/min for 50-120 s.
5）采用用高压均质机、高压动态微射流、胶体磨中的一种或者多种在10-70 MPa下对步骤4）所得料液进行均质。5) Use one or more of high-pressure homogenizer, high-pressure dynamic micro-jet, and colloid mill to homogenize the feed liquid obtained in step 4) at 10-70 MPa.
6）将步骤4）所得样品采用适当的方法如喷雾干燥和冷冻干燥等进行干燥，得到粉状产品，灭菌，真空包装。 6) The sample obtained in step 4) is dried by an appropriate method such as spray drying and freeze drying to obtain a powder product, sterilized, and vacuum-packed.
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