CN107041546A - A kind of amino acid formula powder and preparation method thereof - Google Patents
A kind of amino acid formula powder and preparation method thereof Download PDFInfo
- Publication number
- CN107041546A CN107041546A CN201610081639.6A CN201610081639A CN107041546A CN 107041546 A CN107041546 A CN 107041546A CN 201610081639 A CN201610081639 A CN 201610081639A CN 107041546 A CN107041546 A CN 107041546A
- Authority
- CN
- China
- Prior art keywords
- acid
- amino acid
- formula powder
- mixed
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000843 powder Substances 0.000 title claims abstract description 48
- 235000020616 amino acid formula Nutrition 0.000 title claims abstract description 25
- 238000002360 preparation method Methods 0.000 title claims abstract description 17
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims abstract description 30
- 150000001413 amino acids Chemical class 0.000 claims abstract description 25
- 229910052500 inorganic mineral Inorganic materials 0.000 claims abstract description 17
- 239000011707 mineral Substances 0.000 claims abstract description 17
- DVSZKTAMJJTWFG-SKCDLICFSA-N (2e,4e,6e,8e,10e,12e)-docosa-2,4,6,8,10,12-hexaenoic acid Chemical compound CCCCCCCCC\C=C\C=C\C=C\C=C\C=C\C=C\C(O)=O DVSZKTAMJJTWFG-SKCDLICFSA-N 0.000 claims abstract description 15
- GZJLLYHBALOKEX-UHFFFAOYSA-N 6-Ketone, O18-Me-Ussuriedine Natural products CC=CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O GZJLLYHBALOKEX-UHFFFAOYSA-N 0.000 claims abstract description 15
- 239000005913 Maltodextrin Substances 0.000 claims abstract description 15
- 229920002774 Maltodextrin Polymers 0.000 claims abstract description 15
- 235000020669 docosahexaenoic acid Nutrition 0.000 claims abstract description 15
- KAUVQQXNCKESLC-UHFFFAOYSA-N docosahexaenoic acid (DHA) Natural products COC(=O)C(C)NOCC1=CC=CC=C1 KAUVQQXNCKESLC-UHFFFAOYSA-N 0.000 claims abstract description 15
- IQLUYYHUNSSHIY-HZUMYPAESA-N eicosatetraenoic acid Chemical compound CCCCCCCCCCC\C=C\C=C\C=C\C=C\C(O)=O IQLUYYHUNSSHIY-HZUMYPAESA-N 0.000 claims abstract description 15
- 235000021255 galacto-oligosaccharides Nutrition 0.000 claims abstract description 15
- 150000003271 galactooligosaccharides Chemical class 0.000 claims abstract description 15
- 229940035034 maltodextrin Drugs 0.000 claims abstract description 15
- 229960003080 taurine Drugs 0.000 claims abstract description 15
- 235000015112 vegetable and seed oil Nutrition 0.000 claims abstract description 15
- 239000008158 vegetable oil Substances 0.000 claims abstract description 15
- 229940088594 vitamin Drugs 0.000 claims abstract description 13
- 239000011782 vitamin Substances 0.000 claims abstract description 13
- 235000013343 vitamin Nutrition 0.000 claims abstract description 13
- 229930003231 vitamin Natural products 0.000 claims abstract description 13
- 150000003722 vitamin derivatives Chemical class 0.000 claims abstract description 13
- 229960001231 choline Drugs 0.000 claims abstract description 8
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 claims abstract description 8
- 150000004667 medium chain fatty acids Chemical class 0.000 claims abstract description 8
- 238000007670 refining Methods 0.000 claims abstract description 8
- 239000004480 active ingredient Substances 0.000 claims abstract 2
- 239000002994 raw material Substances 0.000 claims abstract 2
- 239000000463 material Substances 0.000 claims description 44
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 28
- 229940024606 amino acid Drugs 0.000 claims description 23
- 235000001014 amino acid Nutrition 0.000 claims description 23
- 238000001035 drying Methods 0.000 claims description 21
- 235000010755 mineral Nutrition 0.000 claims description 16
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 14
- 235000019742 Vitamins premix Nutrition 0.000 claims description 14
- 238000001816 cooling Methods 0.000 claims description 14
- 238000002156 mixing Methods 0.000 claims description 14
- 239000000203 mixture Substances 0.000 claims description 8
- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 claims description 7
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 7
- 239000001569 carbon dioxide Substances 0.000 claims description 7
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 7
- 229910001873 dinitrogen Inorganic materials 0.000 claims description 7
- 238000004806 packaging method and process Methods 0.000 claims description 7
- 238000009928 pasteurization Methods 0.000 claims description 7
- 239000008213 purified water Substances 0.000 claims description 7
- 229940083466 soybean lecithin Drugs 0.000 claims description 7
- 238000001694 spray drying Methods 0.000 claims description 7
- 230000001954 sterilising effect Effects 0.000 claims description 7
- 238000004659 sterilization and disinfection Methods 0.000 claims description 7
- 239000000126 substance Substances 0.000 claims description 7
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims description 7
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 6
- 238000001704 evaporation Methods 0.000 claims description 6
- 230000000694 effects Effects 0.000 claims description 5
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 4
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 claims description 4
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 claims description 4
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims description 4
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims description 4
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims description 4
- RMRCNWBMXRMIRW-BYFNXCQMSA-M cyanocobalamin Chemical compound N#C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O RMRCNWBMXRMIRW-BYFNXCQMSA-M 0.000 claims description 4
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims description 4
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims description 2
- QDGAVODICPCDMU-UHFFFAOYSA-N 2-amino-3-[3-[bis(2-chloroethyl)amino]phenyl]propanoic acid Chemical compound OC(=O)C(N)CC1=CC=CC(N(CCCl)CCCl)=C1 QDGAVODICPCDMU-UHFFFAOYSA-N 0.000 claims description 2
- 239000001763 2-hydroxyethyl(trimethyl)azanium Substances 0.000 claims description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 2
- 235000019743 Choline chloride Nutrition 0.000 claims description 2
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims description 2
- CKLJMWTZIZZHCS-UHFFFAOYSA-N D-OH-Asp Natural products OC(=O)C(N)CC(O)=O CKLJMWTZIZZHCS-UHFFFAOYSA-N 0.000 claims description 2
- LEVWYRKDKASIDU-QWWZWVQMSA-N D-cystine Chemical compound OC(=O)[C@H](N)CSSC[C@@H](N)C(O)=O LEVWYRKDKASIDU-QWWZWVQMSA-N 0.000 claims description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Natural products NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims description 2
- 239000004471 Glycine Substances 0.000 claims description 2
- CKLJMWTZIZZHCS-UWTATZPHSA-N L-Aspartic acid Natural products OC(=O)[C@H](N)CC(O)=O CKLJMWTZIZZHCS-UWTATZPHSA-N 0.000 claims description 2
- FFEARJCKVFRZRR-UHFFFAOYSA-N L-Methionine Natural products CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 claims description 2
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 claims description 2
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims description 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 claims description 2
- 229930064664 L-arginine Natural products 0.000 claims description 2
- 235000014852 L-arginine Nutrition 0.000 claims description 2
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims description 2
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims description 2
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 claims description 2
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims description 2
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims description 2
- 229930195722 L-methionine Natural products 0.000 claims description 2
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 claims description 2
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims description 2
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims description 2
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims description 2
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims description 2
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims description 2
- KEAYESYHFKHZAL-UHFFFAOYSA-N Sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 claims description 2
- 239000004473 Threonine Substances 0.000 claims description 2
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 claims description 2
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims description 2
- 235000004279 alanine Nutrition 0.000 claims description 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 2
- 229960005261 aspartic acid Drugs 0.000 claims description 2
- 239000011575 calcium Substances 0.000 claims description 2
- 229910052791 calcium Inorganic materials 0.000 claims description 2
- 229960005069 calcium Drugs 0.000 claims description 2
- 235000001465 calcium Nutrition 0.000 claims description 2
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 2
- 235000010216 calcium carbonate Nutrition 0.000 claims description 2
- SGMZJAMFUVOLNK-UHFFFAOYSA-M choline chloride Chemical compound [Cl-].C[N+](C)(C)CCO SGMZJAMFUVOLNK-UHFFFAOYSA-M 0.000 claims description 2
- 229960003178 choline chloride Drugs 0.000 claims description 2
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 claims description 2
- 229960002104 cyanocobalamin Drugs 0.000 claims description 2
- 235000000639 cyanocobalamin Nutrition 0.000 claims description 2
- 239000011666 cyanocobalamin Substances 0.000 claims description 2
- 229960003067 cystine Drugs 0.000 claims description 2
- 230000008020 evaporation Effects 0.000 claims description 2
- 239000011552 falling film Substances 0.000 claims description 2
- 229960001781 ferrous sulfate Drugs 0.000 claims description 2
- 239000011790 ferrous sulphate Substances 0.000 claims description 2
- 235000003891 ferrous sulphate Nutrition 0.000 claims description 2
- 229960000304 folic acid Drugs 0.000 claims description 2
- 235000019152 folic acid Nutrition 0.000 claims description 2
- 239000011724 folic acid Substances 0.000 claims description 2
- 229960002885 histidine Drugs 0.000 claims description 2
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 claims description 2
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 claims description 2
- 229910000359 iron(II) sulfate Inorganic materials 0.000 claims description 2
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims description 2
- 235000019341 magnesium sulphate Nutrition 0.000 claims description 2
- 229940099596 manganese sulfate Drugs 0.000 claims description 2
- 239000011702 manganese sulphate Substances 0.000 claims description 2
- 235000007079 manganese sulphate Nutrition 0.000 claims description 2
- SQQMAOCOWKFBNP-UHFFFAOYSA-L manganese(II) sulfate Chemical compound [Mn+2].[O-]S([O-])(=O)=O SQQMAOCOWKFBNP-UHFFFAOYSA-L 0.000 claims description 2
- 229960004452 methionine Drugs 0.000 claims description 2
- 229960003966 nicotinamide Drugs 0.000 claims description 2
- 235000005152 nicotinamide Nutrition 0.000 claims description 2
- 239000011570 nicotinamide Substances 0.000 claims description 2
- 239000001103 potassium chloride Substances 0.000 claims description 2
- 235000011164 potassium chloride Nutrition 0.000 claims description 2
- 229960002477 riboflavin Drugs 0.000 claims description 2
- 235000019192 riboflavin Nutrition 0.000 claims description 2
- 239000002151 riboflavin Substances 0.000 claims description 2
- 239000011684 sodium molybdate Substances 0.000 claims description 2
- 235000015393 sodium molybdate Nutrition 0.000 claims description 2
- TVXXNOYZHKPKGW-UHFFFAOYSA-N sodium molybdate (anhydrous) Chemical compound [Na+].[Na+].[O-][Mo]([O-])(=O)=O TVXXNOYZHKPKGW-UHFFFAOYSA-N 0.000 claims description 2
- UIERGBJEBXXIGO-UHFFFAOYSA-N thiamine mononitrate Chemical compound [O-][N+]([O-])=O.CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N UIERGBJEBXXIGO-UHFFFAOYSA-N 0.000 claims description 2
- 229960002898 threonine Drugs 0.000 claims description 2
- 229940042585 tocopherol acetate Drugs 0.000 claims description 2
- 239000004474 valine Substances 0.000 claims description 2
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 claims description 2
- 235000005282 vitamin D3 Nutrition 0.000 claims description 2
- 239000011647 vitamin D3 Substances 0.000 claims description 2
- 229940021056 vitamin d3 Drugs 0.000 claims description 2
- 238000004073 vulcanization Methods 0.000 claims description 2
- 238000010792 warming Methods 0.000 claims description 2
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 claims description 2
- 229960001763 zinc sulfate Drugs 0.000 claims description 2
- 229910000368 zinc sulfate Inorganic materials 0.000 claims description 2
- 206010016946 Food allergy Diseases 0.000 abstract description 13
- 235000013350 formula milk Nutrition 0.000 abstract description 8
- 150000004676 glycans Chemical class 0.000 abstract description 3
- 235000016709 nutrition Nutrition 0.000 abstract description 3
- 230000035764 nutrition Effects 0.000 abstract description 3
- 229920001282 polysaccharide Polymers 0.000 abstract description 3
- 239000005017 polysaccharide Substances 0.000 abstract description 3
- 230000002265 prevention Effects 0.000 abstract description 3
- 235000018102 proteins Nutrition 0.000 description 8
- 102000004169 proteins and genes Human genes 0.000 description 8
- 108090000623 proteins and genes Proteins 0.000 description 8
- 235000013336 milk Nutrition 0.000 description 7
- 239000008267 milk Substances 0.000 description 7
- 210000004080 milk Anatomy 0.000 description 7
- 102000014171 Milk Proteins Human genes 0.000 description 4
- 108010011756 Milk Proteins Proteins 0.000 description 4
- 235000021239 milk protein Nutrition 0.000 description 4
- 235000013305 food Nutrition 0.000 description 3
- 206010012438 Dermatitis atopic Diseases 0.000 description 2
- 206010020751 Hypersensitivity Diseases 0.000 description 2
- 208000030961 allergic reaction Diseases 0.000 description 2
- 201000008937 atopic dermatitis Diseases 0.000 description 2
- 230000007062 hydrolysis Effects 0.000 description 2
- 238000006460 hydrolysis reaction Methods 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000002458 infectious effect Effects 0.000 description 2
- 238000001814 protein method Methods 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 1
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 206010002199 Anaphylactic shock Diseases 0.000 description 1
- 208000028185 Angioedema Diseases 0.000 description 1
- 235000017060 Arachis glabrata Nutrition 0.000 description 1
- 244000105624 Arachis hypogaea Species 0.000 description 1
- 235000010777 Arachis hypogaea Nutrition 0.000 description 1
- 235000018262 Arachis monticola Nutrition 0.000 description 1
- 102000011632 Caseins Human genes 0.000 description 1
- 108010076119 Caseins Proteins 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 241000238557 Decapoda Species 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 208000004262 Food Hypersensitivity Diseases 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 102000008192 Lactoglobulins Human genes 0.000 description 1
- 108010060630 Lactoglobulins Proteins 0.000 description 1
- 208000036071 Rhinorrhea Diseases 0.000 description 1
- 206010039101 Rhinorrhoea Diseases 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 241000209140 Triticum Species 0.000 description 1
- 208000024780 Urticaria Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 208000003455 anaphylaxis Diseases 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 235000008452 baby food Nutrition 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 229940021722 caseins Drugs 0.000 description 1
- 208000013116 chronic cough Diseases 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 235000013601 eggs Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 235000019688 fish Nutrition 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 210000003630 histaminocyte Anatomy 0.000 description 1
- 235000020207 hydrolysed-protein milk formula Nutrition 0.000 description 1
- 230000000774 hypoallergenic effect Effects 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 235000014571 nuts Nutrition 0.000 description 1
- 235000020232 peanut Nutrition 0.000 description 1
- 230000009862 primary prevention Effects 0.000 description 1
- 230000004224 protection Effects 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 230000009863 secondary prevention Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000020192 tolerance induction in gut-associated lymphoid tissue Effects 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
It is an object of the invention to disclose a kind of amino acid formula powder and preparation method thereof, the active ingredient contained by it is made up of the raw material of following mass percents:Refining vegetable oil 15 35%, maltodextrin 30 50%, built amino-acid 12 20%, docosahexaenoic acid (DHA) 0.07 0.5%, medium chain fatty acid 6 14%, eicosatetraenoic acid (ARA) 0.1 1.8%, vitamin 0.01 0.1%, mineral matter 1.2 2.4%, FOS(Fos)1 5%, galactooligosaccharide(Gos)1 10%, taurine 0.03 1.0%, L carnitines 0.05 0.5%, choline 0.038 0.240%;It is of great importance using protein-free formula powder for prevention and treatment infant's protein allergies, coordinate with amino acid, vitamin, the formula such as polysaccharide constitutes new amino acid formula powder, to solve the nutrition problem of protein allergies infant, used suitable for the infant of protein allergies, realize the purpose of the present invention.
Description
Technical field
It is more particularly to a kind of not contain amino acid formula powder of protein and preparation method thereof the present invention relates to a kind of amino acid formula powder and preparation method thereof.
Background technology
In recent years, the incidence of infant food allergy is in be gradually increasing trend.Food is relevant in the food hypersenstivity of infant period 90% and milk, egg, soybean, wheat, peanut, fish, shrimp, nut fruits etc. 8.
Milk protein allergy is not tolerated(CMPA/I)It is most common food adverse reaction in baby and underage child, 5%-15% children have doubtful CMPA/I symptom, and the actual incidence of disease is 2%-3%.Simple atopic dermatitis(AD)Middle CMPA/I incidences 37%, CMPA/I children's AD incidences 40%-50% in 1 years old.Some of milk protein such as α-s1 caseins and beta lactoglobulin are anaphylactogens generally acknowledged at present.Under normal circumstances, the allergic reaction of human body will not be caused if both protein can be digested.But, if the digestion power of human body is not enough, both protein may enter human body in undigested form, so as to cause allergic reaction.Medically it is referred to as " milk protein allergy ", its clinical manifestation is one or more following symptoms:Atopic dermatitis, lip or soon swelling, angioedema, non-infectious nettle rash, repeatedly reflux, vomiting and diarrhoea, constipation, have blood in stool, hypoferric anemia, non-infectious runny nose, chronic cough and pant, continue enterospasm even anaphylactic shock etc..
According to the degree hydrolyzed to protein, hypo-allergenic milk powder can be divided into three classes, be amino acid milk powder (AAF), highly hydrolyzed formula milk (eHF) and partial hydrolysis milk powder (pHF) respectively.Due to the immune oral tolerance of appropriate protein hydrolysate formula induction, complete hydrolysis protein prescription avoids activating mast cell, therefore wherein AAF has therapeutic action to milk protein allergy, and pHF has primary prevention effect to High-risk infants, and eHF has secondary prevention/therapeutic action.Amino acid powder is the whole breaks down into amino acids of protein, and the stomach of baby is not directly contacted with protein molecule, thus has blocked anaphylactogen completely, and this can not be referred to as milk powder, because the composition without any " milk ".
Therefore, protein-free formula powder is developed to be of great importance for prevention and treatment infant's protein allergies.Trace element coordinates with amino acid, vitamin as a part indispensable in baby formula milk powder, and the formula such as polysaccharide constitutes new amino acid formula powder, to solve the nutrition problem of protein allergies infant.
The content of the invention
Amino acid formula powder used it is an object of the invention to provide a kind of infant for protein allergies and preparation method thereof, it is more particularly to a kind of not contain amino acid formula powder of protein and preparation method thereof.
To achieve these goals, amino acid formula powder of the present invention is prepared from by the component of following mass percent:
Refining vegetable oil 15-35%, maltodextrin 30-50%, built amino-acid 12-20%, docosahexaenoic acid (DHA) 0.07-0.5%, medium chain fatty acid 6-14%, eicosatetraenoic acid (ARA) 0.1-1.8%, vitamin 0.01-0.1%, mineral matter 1.2-2.4%, FOS(Fos)1-5%, galactooligosaccharide(Gos)1-10%, taurine 0.03-1.0%, VBT 0.05-0.5%, choline 0.038-0.240%.
According to one embodiment of the present invention, the built amino-acid is selected from following one or more of free amino acids:ALANINE, L-arginine, L-Aspartic acid, CYSTINE, L- glycine, L-Histidine, ILE, L-Leu, 1B, L-Methionine, L-phenylalanine, L-PROLINE, Serine, L-threonine, L-Trp, TYR, Valine, Glu.
According to one embodiment of the present invention, the mineral matter is selected from following one or more:Calcium carbonate, magnesium sulfate, potassium chloride, natrium nitrosum, ferrous sulfate, zinc sulfate, manganese sulfate, copper sulphate, vulcanization iodine, sodium molybdate.
According to one embodiment of the present invention, the vitamin is selected from following one or more:Axerophtholum aceticum, Vitamin D3, dl- α-D-α-tocopherol acetate, phytondione, L-AA, Thiamin mononitrate, puridoxine hydrochloride, riboflavin, hydrochloric acid cyanocobalamin, D-VB5 calcium, folic acid, niacinamide, Choline Chloride, Bio.
The preparation method of the amino acid formula powder of the present invention, comprises the following steps:
(1)Dispensing:By the maltodextrin weighed by predetermined ratio, FOS, galactooligosaccharide, mineral substance premix, taurine, VBT, 3.0-5.0 times of the 40-55 DEG C of pure water with alleged material gross weight is added, is sufficiently stirred for, temporary storage tank A is placed in after being well mixed;By the vegetable oil weighed by predetermined ratio, medium chain triglyceride, soybean lecithin, docosahexaenoic acid
(DHA), be sufficiently mixed after eicosatetraenoic acid (ARA) and liposoluble vitamin premix it is uniform after be placed in temporary storage tank B;
(2)Pasteurize:After material in temporary storage tank A, temporary storage tank B is mixed, be placed in pasteurization machine, 80-100 DEG C maintains 5-10 minutes, after be quickly cooled to 35-45 DEG C;
(3)Mix homogeneous:Water soluble vitamin premix is added after 10.0-20.0 times of dissolved in purified water for claiming material gross weight, be added to the mixed material after sterilization, be placed in homogeneous in high pressure homogenizer, be heated up to 60-70 DEG C, pressure condition is 10-20MPa.After be cooled to less than 10 DEG C keep in;
(4)Concentration:It is 15-25 ° of B é that mixed material is concentrated into Baume degrees;
(5)Spray drying:Material after concentration is spray-dried, drying condition is:Pressure 15-20MPa, 150-240 DEG C of EAT, temperature of outgoing air is 70-90 DEG C;
(6)Fluidized bed drying is cooled down:Using fluidized bed drying and cooling, it is 2.0-3.0Wt% to control logistics water content, after cooling, obtains base stock powder;
(7)Batch mixing:The built amino-acid premix weighed by predetermined ratio is added in base stock powder, is placed in three-dimensional dry-mixed machine, batch mixing 20-30 minutes;
(8)Packaging:Packed using vacuum nitrogen gas or carbon dioxide.
According to one embodiment of the present invention, the concentration step is concentrated to be concentrated in vacuo using double-effect falling film evaporator, and the first effect vacuum is 30-42kPa, and evaporating temperature is 70-75 DEG C;Second effect vacuum is 60-70kPa, and evaporating temperature is 45-52 DEG C.
According to one embodiment of the present invention, the concentration step evaporates to be concentrated by evaporation under the conditions of the mixed material after homogeneous is warming up into 60-70 DEG C.
Amino acid formula powder of the present invention and preparation method thereof, compared with prior art, it is of great importance using protein-free formula powder for prevention and treatment infant's protein allergies, coordinate with amino acid, vitamin, the formula such as polysaccharide constitutes new amino acid formula powder, to solve the nutrition problem of protein allergies infant, used suitable for the infant of protein allergies, realize the purpose of the present invention.
Embodiment
In order that the technical means, the inventive features, the objects and the advantages of the present invention are easy to understand, the present invention is expanded on further with reference to specific embodiment.
Embodiment
1
Amino acid formula powder by component it is as follows:
Refining vegetable oil 20%, maltodextrin 45%, built amino-acid 16%, docosahexaenoic acid (DHA) 0.3%, medium chain fatty acid 9.8%, eicosatetraenoic acid (ARA) 0.48%, vitamin 0.07%, mineral matter 1.8%, FOS(Fos)2%, galactooligosaccharide(Gos)4%, taurine 0.3%, VBT 0.2%, choline 0.05%.
Preparation method is as follows:
(1)Dispensing:By the maltodextrin weighed by predetermined ratio, FOS, galactooligosaccharide, mineral substance premix, taurine, VBT, 3.0-5.0 times of the 40-55 DEG C of pure water with alleged material gross weight is added, is sufficiently stirred for, temporary storage tank A is placed in after being well mixed;By the vegetable oil weighed by predetermined ratio, medium chain triglyceride, soybean lecithin, docosahexaenoic acid
(DHA), be sufficiently mixed after eicosatetraenoic acid (ARA) and liposoluble vitamin premix it is uniform after be placed in temporary storage tank B;
(2)Pasteurize:After material in temporary storage tank A, temporary storage tank B is mixed, be placed in pasteurization machine, 80-100 DEG C maintains 5-10 minutes, after be quickly cooled to 35-45 DEG C;
(3)Mix homogeneous:Water soluble vitamin premix is added after 10.0-20.0 times of dissolved in purified water for claiming material gross weight, be added to the mixed material after sterilization, be placed in homogeneous in high pressure homogenizer, be heated up to 60-70 DEG C, pressure condition is 10-20MPa.After be cooled to less than 10 DEG C keep in;
(4)Concentration:It is 15-25 ° of B é that mixed material is concentrated into Baume degrees;
(5)Spray drying:Material after concentration is spray-dried, drying condition is:Pressure 15-20MPa, 150-240 DEG C of EAT, temperature of outgoing air is 70-90 DEG C;
(6)Fluidized bed drying is cooled down:Using fluidized bed drying and cooling, it is 2.0-3.0Wt% to control logistics water content, after cooling, obtains base stock powder;
(7)Batch mixing:The built amino-acid premix weighed by predetermined ratio is added in base stock powder, is placed in three-dimensional dry-mixed machine, batch mixing 20-30 minutes;
(8)Packaging:Packed using vacuum nitrogen gas or carbon dioxide.
Embodiment
2
Amino acid formula powder by component it is as follows:
Refining vegetable oil 16%, maltodextrin 42%, built amino-acid 15.5%, docosahexaenoic acid (DHA) 0.18%, medium chain fatty acid 12%, eicosatetraenoic acid (ARA) 0.6%, vitamin 0.08%, mineral matter 1.94%, FOS(Fos)4.6%, galactooligosaccharide(Gos)5.8%, taurine 0.8%, VBT 0.4%, choline 0.1%.
Preparation method is as follows:
(1)Dispensing:By the maltodextrin weighed by predetermined ratio, FOS, galactooligosaccharide, mineral substance premix, taurine, VBT, 3.0-5.0 times of the 40-55 DEG C of pure water with alleged material gross weight is added, is sufficiently stirred for, temporary storage tank A is placed in after being well mixed;By the vegetable oil weighed by predetermined ratio, medium chain triglyceride, soybean lecithin, docosahexaenoic acid
(DHA), be sufficiently mixed after eicosatetraenoic acid (ARA) and liposoluble vitamin premix it is uniform after be placed in temporary storage tank B;
(2)Pasteurize:After material in temporary storage tank A, temporary storage tank B is mixed, be placed in pasteurization machine, 80-100 DEG C maintains 5-10 minutes, after be quickly cooled to 35-45 DEG C;
(3)Mix homogeneous:Water soluble vitamin premix is added after 10.0-20.0 times of dissolved in purified water for claiming material gross weight, be added to the mixed material after sterilization, be placed in homogeneous in high pressure homogenizer, be heated up to 60-70 DEG C, pressure condition is 10-20MPa.After be cooled to less than 10 DEG C keep in;
(4)Concentration:It is 15-25 ° of B é that mixed material is concentrated into Baume degrees;
(5)Spray drying:Material after concentration is spray-dried, drying condition is:Pressure 15-20MPa, 150-240 DEG C of EAT, temperature of outgoing air is 70-90 DEG C;
(6)Fluidized bed drying is cooled down:Using fluidized bed drying and cooling, it is 2.0-3.0Wt% to control logistics water content, after cooling, obtains base stock powder;
(7)Batch mixing:The built amino-acid premix weighed by predetermined ratio is added in base stock powder, is placed in three-dimensional dry-mixed machine, batch mixing 20-30 minutes;
(8)Packaging:Packed using vacuum nitrogen gas or carbon dioxide.
Embodiment
3
Amino acid formula powder by component it is as follows:
Refining vegetable oil 16%, maltodextrin 50%, built amino-acid 17.5%, docosahexaenoic acid (DHA) 0.2%, medium chain fatty acid 6%, eicosatetraenoic acid (ARA) 1.1%, vitamin 0.1%, mineral matter 2.4%, FOS(Fos)2.1%, galactooligosaccharide(Gos)3.1%, taurine 0.9%, VBT 0.5%, choline 0.1%.
Preparation method is as follows:
(1)Dispensing:By the maltodextrin weighed by predetermined ratio, FOS, galactooligosaccharide, mineral substance premix, taurine, VBT, 3.0-5.0 times of the 40-55 DEG C of pure water with alleged material gross weight is added, is sufficiently stirred for, temporary storage tank A is placed in after being well mixed;By the vegetable oil weighed by predetermined ratio, medium chain triglyceride, soybean lecithin, docosahexaenoic acid
(DHA), be sufficiently mixed after eicosatetraenoic acid (ARA) and liposoluble vitamin premix it is uniform after be placed in temporary storage tank B;
(2)Pasteurize:After material in temporary storage tank A, temporary storage tank B is mixed, be placed in pasteurization machine, 80-100 DEG C maintains 5-10 minutes, after be quickly cooled to 35-45 DEG C;
(3)Mix homogeneous:Water soluble vitamin premix is added after 10.0-20.0 times of dissolved in purified water for claiming material gross weight, be added to the mixed material after sterilization, be placed in homogeneous in high pressure homogenizer, be heated up to 60-70 DEG C, pressure condition is 10-20MPa.After be cooled to less than 10 DEG C keep in;
(4)Concentration:It is 15-25 ° of B é that mixed material is concentrated into Baume degrees;
(5)Spray drying:Material after concentration is spray-dried, drying condition is:Pressure 15-20MPa, 150-240 DEG C of EAT, temperature of outgoing air is 70-90 DEG C;
(6)Fluidized bed drying is cooled down:Using fluidized bed drying and cooling, it is 2.0-3.0Wt% to control logistics water content, after cooling, obtains base stock powder;
(7)Batch mixing:The built amino-acid premix weighed by predetermined ratio is added in base stock powder, is placed in three-dimensional dry-mixed machine, batch mixing 20-30 minutes;
(8)Packaging:Packed using vacuum nitrogen gas or carbon dioxide.
Embodiment
4
Amino acid formula powder by component it is as follows:
Refining vegetable oil 15%, maltodextrin 30%, built amino-acid 20%, docosahexaenoic acid (DHA) 0.5%, medium chain fatty acid 14%, eicosatetraenoic acid (ARA) 1.8%, vitamin 0.9%, mineral matter 2.36%, FOS(Fos)5%, galactooligosaccharide(Gos)10%, taurine 0.1%, VBT 0.1%, choline 0.24%.
Preparation method is as follows:
(1)Dispensing:By the maltodextrin weighed by predetermined ratio, FOS, galactooligosaccharide, mineral substance premix, taurine, VBT, 3.0-5.0 times of the 40-55 DEG C of pure water with alleged material gross weight is added, is sufficiently stirred for, temporary storage tank A is placed in after being well mixed;By the vegetable oil weighed by predetermined ratio, medium chain triglyceride, soybean lecithin, docosahexaenoic acid
(DHA), be sufficiently mixed after eicosatetraenoic acid (ARA) and liposoluble vitamin premix it is uniform after be placed in temporary storage tank B;
(2)Pasteurize:After material in temporary storage tank A, temporary storage tank B is mixed, be placed in pasteurization machine, 80-100 DEG C maintains 5-10 minutes, after be quickly cooled to 35-45 DEG C;
(3)Mix homogeneous:Water soluble vitamin premix is added after 10.0-20.0 times of dissolved in purified water for claiming material gross weight, be added to the mixed material after sterilization, be placed in homogeneous in high pressure homogenizer, be heated up to 60-70 DEG C, pressure condition is 10-20MPa.After be cooled to less than 10 DEG C keep in;
(4)Concentration:It is 15-25 ° of B é that mixed material is concentrated into Baume degrees;
(5)Spray drying:Material after concentration is spray-dried, drying condition is:Pressure 15-20MPa, 150-240 DEG C of EAT, temperature of outgoing air is 70-90 DEG C;
(6)Fluidized bed drying is cooled down:Using fluidized bed drying and cooling, it is 2.0-3.0Wt% to control logistics water content, after cooling, obtains base stock powder;
(7)Batch mixing:The built amino-acid premix weighed by predetermined ratio is added in base stock powder, is placed in three-dimensional dry-mixed machine, batch mixing 20-30 minutes;
(8)Packaging:Packed using vacuum nitrogen gas or carbon dioxide.
Embodiment
5
Amino acid formula powder by component it is as follows:
Refining vegetable oil 35%, maltodextrin 35.502%, built amino-acid 12%, docosahexaenoic acid (DHA) 0.07%, medium chain fatty acid 14%, eicosatetraenoic acid (ARA) 0.1%, vitamin 0.01%, mineral matter 1.2%, FOS(Fos)1%, galactooligosaccharide(Gos)1%, taurine 0.03%, VBT 0.05%, choline 0.038%.
Preparation method is as follows:
(1)Dispensing:By the maltodextrin weighed by predetermined ratio, FOS, galactooligosaccharide, mineral substance premix, taurine, VBT, 3.0-5.0 times of the 40-55 DEG C of pure water with alleged material gross weight is added, is sufficiently stirred for, temporary storage tank A is placed in after being well mixed;By the vegetable oil weighed by predetermined ratio, medium chain triglyceride, soybean lecithin, docosahexaenoic acid
(DHA), be sufficiently mixed after eicosatetraenoic acid (ARA) and liposoluble vitamin premix it is uniform after be placed in temporary storage tank B;
(2)Pasteurize:After material in temporary storage tank A, temporary storage tank B is mixed, be placed in pasteurization machine, 80-100 DEG C maintains 5-10 minutes, after be quickly cooled to 35-45 DEG C;
(3)Mix homogeneous:Water soluble vitamin premix is added after 10.0-20.0 times of dissolved in purified water for claiming material gross weight, be added to the mixed material after sterilization, be placed in homogeneous in high pressure homogenizer, be heated up to 60-70 DEG C, pressure condition is 10-20MPa.After be cooled to less than 10 DEG C keep in;
(4)Concentration:It is 15-25 ° of B é that mixed material is concentrated into Baume degrees;
(5)Spray drying:Material after concentration is spray-dried, drying condition is:Pressure 15-20MPa, 150-240 DEG C of EAT, temperature of outgoing air is 70-90 DEG C;
(6)Fluidized bed drying is cooled down:Using fluidized bed drying and cooling, it is 2.0-3.0Wt% to control logistics water content, after cooling, obtains base stock powder;
(7)Batch mixing:The built amino-acid premix weighed by predetermined ratio is added in base stock powder, is placed in three-dimensional dry-mixed machine, batch mixing 20-30 minutes;
(8)Packaging:Packed using vacuum nitrogen gas or carbon dioxide.
General principle, principal character and the advantages of the present invention of the present invention has been shown and described above.It should be understood by those skilled in the art that; the present invention is not limited to the above embodiments; the principle of the simply present invention described in above-described embodiment and specification; various changes and modifications of the present invention are possible without departing from the spirit and scope of the present invention, and these changes and improvements are both fallen within the range of claimed invention.The protection domain of application claims is defined by appended claims and its equivalent.
Claims (7)
1. a kind of amino acid formula powder, it is characterised in that the active ingredient contained by it is made up of the raw material of following mass percents:
Refining vegetable oil 15-35%, maltodextrin 30-50%, built amino-acid 12-20%, docosahexaenoic acid (DHA) 0.07-0.5%, medium chain fatty acid 6-14%, eicosatetraenoic acid (ARA) 0.1-1.8%, vitamin 0.01-0.1%, mineral matter 1.2-2.4%, FOS(Fos)1-5%, galactooligosaccharide(Gos)1-10%, taurine 0.03-1.0%, VBT 0.05-0.5%, choline 0.038-0.240%.
2. amino acid formula powder according to claim 1, it is characterised in that the built amino-acid is selected from following one or more of free amino acids:ALANINE, L-arginine, L-Aspartic acid, CYSTINE, L- glycine, L-Histidine, ILE, L-Leu, 1B, L-Methionine, L-phenylalanine, L-PROLINE, Serine, L-threonine, L-Trp, TYR, Valine, Glu.
3. amino acid formula powder according to claim 1, it is characterised in that the mineral matter is selected from following one or more:Calcium carbonate, magnesium sulfate, potassium chloride, natrium nitrosum, ferrous sulfate, zinc sulfate, manganese sulfate, copper sulphate, vulcanization iodine, sodium molybdate.
4. amino acid formula powder according to claim 1, it is characterised in that the vitamin is selected from following one or more:Axerophtholum aceticum, Vitamin D3, dl- α-D-α-tocopherol acetate, phytondione, L-AA, Thiamin mononitrate, puridoxine hydrochloride, riboflavin, hydrochloric acid cyanocobalamin, D-VB5 calcium, folic acid, niacinamide, Choline Chloride, Bio.
5. a kind of preparation method of amino acid formula powder, it is characterised in that comprise the following steps:
(1)Dispensing:By the maltodextrin weighed by predetermined ratio, FOS, galactooligosaccharide, mineral substance premix, taurine, VBT, 3.0-5.0 times of the 40-55 DEG C of pure water with alleged material gross weight is added, is sufficiently stirred for, temporary storage tank A is placed in after being well mixed;By the vegetable oil weighed by predetermined ratio, medium chain triglyceride, soybean lecithin, docosahexaenoic acid (DHA), be sufficiently mixed after eicosatetraenoic acid (ARA) and liposoluble vitamin premix it is uniform after be placed in temporary storage tank B;
(2)Pasteurize:After material in temporary storage tank A, temporary storage tank B is mixed, be placed in pasteurization machine, 80-100 DEG C maintains 5-10 minutes, after be quickly cooled to 35-45 DEG C;
(3)Mix homogeneous:Water soluble vitamin premix is added after 10.0-20.0 times of dissolved in purified water for claiming material gross weight, be added to the mixed material after sterilization, be placed in homogeneous in high pressure homogenizer, be heated up to 60-70 DEG C, pressure condition is 10-20MPa;After be cooled to less than 10 DEG C keep in;
(4)Concentration:It is 15-25 ° of B é that mixed material is concentrated into Baume degrees;
(5)Spray drying:Material after concentration is spray-dried, drying condition is:Pressure 15-20MPa, 150-240 DEG C of EAT, temperature of outgoing air is 70-90 DEG C;
(6)Fluidized bed drying is cooled down:Using fluidized bed drying and cooling, it is 2.0-3.0Wt% to control logistics water content, after cooling, obtains base stock powder;
(7)Batch mixing:The built amino-acid premix weighed by predetermined ratio is added in base stock powder, is placed in three-dimensional dry-mixed machine, batch mixing 20-30 minutes;
(8)Packaging:Packed using vacuum nitrogen gas or carbon dioxide.
6. the preparation method of amino acid formula powder according to claim 5, it is characterised in that the concentration step is concentrated to be concentrated in vacuo using double-effect falling film evaporator, the first effect vacuum is 30-42kPa, evaporating temperature is 70-75 DEG C;Second effect vacuum is 60-70kPa, and evaporating temperature is 45-52 DEG C.
7. the preparation method of amino acid formula powder according to claim 5, it is characterised in that the concentration step evaporates to be concentrated by evaporation under the conditions of the mixed material after homogeneous is warming up into 60-70 DEG C.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610081639.6A CN107041546A (en) | 2016-02-05 | 2016-02-05 | A kind of amino acid formula powder and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610081639.6A CN107041546A (en) | 2016-02-05 | 2016-02-05 | A kind of amino acid formula powder and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN107041546A true CN107041546A (en) | 2017-08-15 |
Family
ID=59543689
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610081639.6A Pending CN107041546A (en) | 2016-02-05 | 2016-02-05 | A kind of amino acid formula powder and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN107041546A (en) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108294306A (en) * | 2018-04-03 | 2018-07-20 | 健行天下生物技术有限公司 | A kind of full nutrition special medicine purposes formula food of amino acid pattern |
CN108795437A (en) * | 2018-03-27 | 2018-11-13 | 和和乐和(天津)环境科技有限公司 | A kind of soil remediation complexing agent based on maltodextrin |
CN108936690A (en) * | 2018-03-14 | 2018-12-07 | 山东梵和生物科技有限公司 | A kind of amino acid formula powder and preparation method thereof |
CN108991503A (en) * | 2018-07-11 | 2018-12-14 | 谢碧平 | A kind of baby's special formulation powder rich in microelement |
CN109497533A (en) * | 2019-01-03 | 2019-03-22 | 贝因美(杭州)食品研究院有限公司 | A kind of agalasisa glycoprotein amino acid infant formula and preparation method thereof suitable for food protein allergy baby |
CN110122881A (en) * | 2019-05-09 | 2019-08-16 | 海普诺凯营养品有限公司 | A kind of alimentation composition promoting child height development |
CN110663958A (en) * | 2019-10-23 | 2020-01-10 | 汕头市培芝食品有限公司 | Complementary food containing amino acid powder for infants and preparation method thereof |
WO2020010895A1 (en) * | 2018-07-10 | 2020-01-16 | 宁波特壹食品有限公司 | Amino acid-based formula powder and preparation method thereof |
CN117837750A (en) * | 2024-01-16 | 2024-04-09 | 费森尤斯卡比华瑞制药有限公司 | Formula powder preparation method, device, computer readable medium and formula powder |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1358500A (en) * | 2000-12-13 | 2002-07-17 | 诺瓦提斯营养股份公司 | Baby preparation containing free amino-acid and nucleotide |
US20040265462A1 (en) * | 2003-06-24 | 2004-12-30 | University Of Kansas Medical Center | Nutritional supplement |
CN101795579A (en) * | 2006-08-04 | 2010-08-04 | Shs国际有限公司 | Protein free formula |
CN101848649A (en) * | 2007-11-07 | 2010-09-29 | 美赞臣营养品公司 | The method that is used to reduce the bitter taste of no albumen and hydrolyzed infant prescription and improves its taste |
CN101978841A (en) * | 2010-08-31 | 2011-02-23 | 浙江贝因美科工贸股份有限公司 | Protein allergy-resisting and nutritious infant formula milk powder |
CN102083330A (en) * | 2008-07-07 | 2011-06-01 | 雀巢产品技术援助有限公司 | A nutritional composition with free amino acids and structured lipids |
CN104012657A (en) * | 2014-05-21 | 2014-09-03 | 澳优乳业(中国)有限公司 | Amino acid humanized infant formula milk powder and preparation method thereof |
CN104054828A (en) * | 2014-06-23 | 2014-09-24 | 中恩(天津)营养科技有限公司 | Infant formula milk powder resisting protein allergy and preparation method thereof |
CN104968217A (en) * | 2013-02-12 | 2015-10-07 | 乌列·科斯勒 | non-dairy formula |
CN105029393A (en) * | 2015-04-10 | 2015-11-11 | 劲膳美生物科技股份有限公司 | Medical formula food for children |
-
2016
- 2016-02-05 CN CN201610081639.6A patent/CN107041546A/en active Pending
Patent Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1358500A (en) * | 2000-12-13 | 2002-07-17 | 诺瓦提斯营养股份公司 | Baby preparation containing free amino-acid and nucleotide |
US20040265462A1 (en) * | 2003-06-24 | 2004-12-30 | University Of Kansas Medical Center | Nutritional supplement |
CN101795579A (en) * | 2006-08-04 | 2010-08-04 | Shs国际有限公司 | Protein free formula |
CN101848649A (en) * | 2007-11-07 | 2010-09-29 | 美赞臣营养品公司 | The method that is used to reduce the bitter taste of no albumen and hydrolyzed infant prescription and improves its taste |
CN102083330A (en) * | 2008-07-07 | 2011-06-01 | 雀巢产品技术援助有限公司 | A nutritional composition with free amino acids and structured lipids |
CN103892271A (en) * | 2008-07-07 | 2014-07-02 | 雀巢产品技术援助有限公司 | Nutritional composition with free amino acids and structured lipids |
CN101978841A (en) * | 2010-08-31 | 2011-02-23 | 浙江贝因美科工贸股份有限公司 | Protein allergy-resisting and nutritious infant formula milk powder |
CN104968217A (en) * | 2013-02-12 | 2015-10-07 | 乌列·科斯勒 | non-dairy formula |
CN104012657A (en) * | 2014-05-21 | 2014-09-03 | 澳优乳业(中国)有限公司 | Amino acid humanized infant formula milk powder and preparation method thereof |
CN104054828A (en) * | 2014-06-23 | 2014-09-24 | 中恩(天津)营养科技有限公司 | Infant formula milk powder resisting protein allergy and preparation method thereof |
CN105029393A (en) * | 2015-04-10 | 2015-11-11 | 劲膳美生物科技股份有限公司 | Medical formula food for children |
Non-Patent Citations (1)
Title |
---|
纽迪希亚特配营养旗舰店: "纽康特neocate氨基酸配方适用食物蛋白过敏婴儿英国原装进口400g", 《HTTPS://DETAIL.TMALL.COM/ITEM.HTM?SPM=A1Z10.1-B-S.W5003-22307186634.6.17611760YS9K5A&ID=37264157388&SCENE=TAOBAO_SHOP》 * |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108936690A (en) * | 2018-03-14 | 2018-12-07 | 山东梵和生物科技有限公司 | A kind of amino acid formula powder and preparation method thereof |
CN108795437A (en) * | 2018-03-27 | 2018-11-13 | 和和乐和(天津)环境科技有限公司 | A kind of soil remediation complexing agent based on maltodextrin |
CN108294306A (en) * | 2018-04-03 | 2018-07-20 | 健行天下生物技术有限公司 | A kind of full nutrition special medicine purposes formula food of amino acid pattern |
WO2020010895A1 (en) * | 2018-07-10 | 2020-01-16 | 宁波特壹食品有限公司 | Amino acid-based formula powder and preparation method thereof |
CN110693004A (en) * | 2018-07-10 | 2020-01-17 | 杨国民 | Amino acid formula powder and preparation method thereof |
CN108991503A (en) * | 2018-07-11 | 2018-12-14 | 谢碧平 | A kind of baby's special formulation powder rich in microelement |
CN109497533A (en) * | 2019-01-03 | 2019-03-22 | 贝因美(杭州)食品研究院有限公司 | A kind of agalasisa glycoprotein amino acid infant formula and preparation method thereof suitable for food protein allergy baby |
CN110122881A (en) * | 2019-05-09 | 2019-08-16 | 海普诺凯营养品有限公司 | A kind of alimentation composition promoting child height development |
CN110663958A (en) * | 2019-10-23 | 2020-01-10 | 汕头市培芝食品有限公司 | Complementary food containing amino acid powder for infants and preparation method thereof |
CN117837750A (en) * | 2024-01-16 | 2024-04-09 | 费森尤斯卡比华瑞制药有限公司 | Formula powder preparation method, device, computer readable medium and formula powder |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN107041546A (en) | A kind of amino acid formula powder and preparation method thereof | |
US8835383B2 (en) | Method for controlling the digestive coagulation of proteins | |
EP2442673B1 (en) | Nutritional powders comprising spray dried hmb | |
EP2757898B1 (en) | Powdered nutritional formulations including spray-dried plant protein | |
JP5892948B2 (en) | Nutritional emulsion containing calcium HMB | |
AU2007280272A1 (en) | Protein free formula | |
CN103491973B (en) | For preventing the infant formula product of cardiovascular disease | |
TW200816933A (en) | Nutritional formulations containing octenyl succinate anhydride-modified tapioca starch | |
CN110663958A (en) | Complementary food containing amino acid powder for infants and preparation method thereof | |
EP2797431A1 (en) | Reduced calorie infant formulas containing specific whey to casein ratios | |
CN104619181B (en) | Method for preparing protein-containing composition for reducing digestive coagulation | |
EP2869707B2 (en) | Method for producing a protein and lipid comprising composition with reduced digestive coagulation | |
ES2776433T3 (en) | Nutrition of infants with hydrolyzed proteins, ionic calcium and palmitic acid | |
CN110074189A (en) | A kind of infant's diatery supplement and preparation method thereof adding human milk oligosaccharides | |
JP2750467B2 (en) | Peptide mixture and enteral nutrition composition | |
US20170295836A1 (en) | Nutritional powders comprising spray dried hmb | |
CN107105739A (en) | Infant nutrition containing aminosal and palmitic acid | |
EP3574770A1 (en) | Amino acid-containing composition | |
WO2020252949A1 (en) | Protein composite for preventing and relieving sarcopenia in patients suffering from type 2 diabetes, and preparation method | |
CN100364969C (en) | Water soluble vitamins D2 preparation method | |
CN112167347B (en) | Infant formula milk powder containing gastrointestinal regulating peptide and preparation method thereof | |
CN119184309A (en) | Nutritional composition containing extensively hydrolyzed casein, food and use thereof | |
HK1165227B (en) | Nutritional powders comprising spray dried hmb | |
HK1200060B (en) | Powdered nutritional formulations including spray-dried plant protein | |
JP2005154401A (en) | Deodorizing composition for feces |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20181012 Address after: 315336 <1-1>, <1-2>, <1-3>, <1-4>, 18 building 77, Binhai two road, Hangzhou Bay New District, Ningbo, Zhejiang. Applicant after: Ningbo te Yi Food Co., Ltd. Address before: 200061 606, room 1, 381 Wan Ping South Road, Xuhui District, Shanghai. Applicant before: Shanghai tappuah Trading Co. Ltd. |
|
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170815 |