CN107019551A - A kind of carried medicine sustained-release, flushing and vacuum suction steel plate - Google Patents

Abstract

The invention discloses a drug-loaded slow-release, flushing and negative pressure suction steel plate, which comprises a steel plate, screw holes are distributed on the steel plate, flushing branch pipes and suction pipes are distributed inside the steel plate, wherein the flushing branch pipes are connected to the main flushing pipe, and the suction pipes The pipe is connected to the suction main pipe, and both the flushing main pipe and the suction main pipe pass through the upper surface of the steel plate; the upper surface of the steel plate is distributed with leakage holes connected with the flushing branch pipe, and the upper surface of the steel plate and the side of the steel plate are distributed with A suction hole in communication with the flushing branch. The present invention effectively solves the problem of infection control of internal plants, has the functions of drug slow release, negative pressure suction and flushing, does not need to take out the internal plants when the infection is serious, and the fracture can continue to heal without secondary fixation, thereby saving Medical resources, reducing the suffering and economic burden of patients.

Description

A drug-loaded slow-release, flushing and negative pressure suction steel plate

technical field

The invention relates to an orthopedic internal plant, in particular to a drug-loaded slow-release, flushing and negative pressure suction steel plate, which is used to solve the infection problem in the application of the internal plant.

Background technique

The advancement of implants is one of the important components of the development of modern orthopedics. Internal fixation of fractures represented by bone plates, screws, and intramedullary nails is currently a routine treatment technique in trauma orthopedics, and artificial joint replacement is an effective method for treating advanced osteoarthritis, eliminating joint pain and improving function; Known as a great breakthrough in the field of orthopedics in the 20th century. According to statistics, more than 800,000 orthopedic implant surgeries are performed in Europe every year. In the United States, more than 200,000 patients undergo joint replacement every year, and as of 2010, a total of more than 4.4 million patients in the United States received internal fixation for fractures. Since 2005, there have been more than 400,000 casualties in traffic accidents in my country every year, and the vast majority of patients have one or more fractures and need internal fixation surgery.

One of the greatest risks with implant applications is infection. Studies have shown that in the absence of foreign objects such as internal plants, 100,000 bacteria per gram of tissue can cause infection. However, in the presence of a foreign body, the number of bacteria required for infection dropped dramatically, with as little as 100 bacteria per gram of tissue contamination leading to a fatal infection. The study showed an infection rate of 1.6 percent after primary hip replacement and an average infection rate of 1.3 percent after primary knee replacement. However, the average infection rate after the initial internal fixation of fractures is greater than 5%, especially the infection rate after the initial internal fixation of open fractures is as high as 30%. The most worrying and thorny problem for medical staff is the infection of internal plants. In spite of strict preoperative disinfection, intraoperative aseptic operation and application of antibiotics and other powerful measures, the occurrence of infection cannot be avoided. Implant infection is a catastrophic event after orthopedic surgery. Once implant infection occurs, fractures are difficult to heal, which not only brings great pain to patients, but also wastes a lot of medical and health resources, causing huge economic losses to the country and individuals. It goes without saying that the control of plant infection is of great significance.

At present, in the clinical treatment of internal plant infection, methods such as taking out the internal plant, thoroughly debridement, placing antibiotic beads, etc. are mostly used, and re-implant the internal plant after the infection is controlled; however, the current method will seriously delay the healing time and bring pain to the patient. came a heavy economic burden.

Contents of the invention

In view of the problems existing in the above-mentioned prior art, the purpose of the present invention is to provide a drug-loaded slow-release, flushing and negative pressure suction steel plate to solve the infection problem during the application of internal plants, thereby reducing the application risk of internal plants, Reduce the pain and economic burden of patients; it is mainly used for patients with open fractures.

In order to achieve the above tasks, the present invention adopts the following technical solutions:

A drug-loaded slow-release, flushing and negative-pressure suction steel plate, comprising a steel plate, screw holes are distributed on the steel plate, flushing branch pipes and suction pipes are distributed inside the steel plate, wherein the flushing branch pipes are connected to the main flushing pipe, and the suction pipes are connected to the suction pipe. The suction main pipe, the flushing main pipe and the suction main pipe all pass through the upper surface of the steel plate;

The upper surface of the steel plate is distributed with leakage holes communicating with the flushing branch pipe, and the upper surface of the steel plate and the side of the steel plate are distributed with suction holes connected with the flushing branch pipe.

Further, the drug-loaded slow-release, flushing and negative pressure suction steel plate also includes a slow-release flushing bag, and the inside of the slow-release flushing bag is separated by two partitions into a first side bag, a second side bag and a side bag on both sides. The middle bag in the middle is provided with a first one-way valve on both diaphragms, and the first one-way valve only allows fluid to flow into the middle bag from the first side bag or the second side bag; the middle bag is provided with There is an intubation matched with the flushing main pipe, and a second one-way valve is arranged in the intubation.

Further, the suction pipe is distributed on the edge of the steel plate, forming a closed loop; the flushing branch pipe is distributed on both sides of the screw hole.

Further, the steel plate has a rectangular structure, the main flushing pipe is located at the center of the upper surface of the steel plate, and the branch flushing pipes are distributed along the length direction of the steel plate on both sides of the main flushing pipe, and are finally connected by the first connecting pipe to the flushing mains.

Further, the suction pipe includes a first suction pipe and a second suction pipe, wherein the first suction pipe is distributed at the edge of the steel plate in the longitudinal direction, the second suction pipe is distributed at the edge of the steel plate in the width direction, and the first suction pipe , The ends of the second suction pipe are connected, and both pass through the side or end surface of the steel plate.

Further, the suction hole includes a first suction hole and a second suction hole, wherein the first suction hole is distributed on the edge of the upper surface of the steel plate, and the second suction hole is distributed on the side and end surface of the steel plate, Both the first suction hole and the second suction hole communicate with the first suction pipe or the second suction pipe.

Further, the first side bag, the second side bag and the middle bag have the same volume and are all air bags.

Compared with the prior art, the present invention has the following technical characteristics:

1. The present invention can realize the sustained-release function of the drug, and the effective concentration of the drug can be achieved locally on the wound surface without systemic application of antibiotics, thereby reducing the dosage of the drug and improving the effect of the drug; the drug in the present invention can be released in stages , can have a better therapeutic effect, and the drug release process is non-invasive, without incision;

2. The drug release and negative pressure washing process in the present invention are very simple to operate, which can effectively reduce the number of operations, thereby reducing the risk of surgery, reducing the pain and economic burden of patients, and improving the work efficiency of medical staff;

3. In the present invention, negative pressure suction can be used to suck out the drainage fluid for qualitative culture to clarify bacteria, so that sensitive antibiotics can be used to wash the wound surface in a targeted manner to achieve better therapeutic effect; in addition, the negative pressure suction effect can be achieved by suction The traction stimulation promotes the formation of fresh granulation tissue at the micropores on the surface of the steel plate, which is beneficial to the healing of deep tissues;

4. The present invention solves the problem of implant infection control. It is not necessary to take out the implant when the infection is severe, and the fracture site can continue to heal without secondary fixation; and the steel plate can be removed after the fracture has healed to a certain extent, and then cleaned thoroughly. Innovative, the medical device effectively saves medical resources and has a good prospect for transformation.

Description of drawings

Fig. 1 is a schematic top view of the overall structure of the present invention;

Fig. 2 is the side structure schematic diagram of Fig. 1 (the A direction view of Fig. 1);

Fig. 3 is the schematic view of the end face structure of Fig. 1 (the B direction view of Fig. 1);

Fig. 4 is a schematic sectional view taken along the line C-C of Fig. 1;

Fig. 5 is a structural schematic diagram of the matching part of the slow-release flushing bag and the steel plate;

The symbols in the figure represent: 1—steel plate, 2—flushing main pipe, 3—first connecting pipe, 4—flushing branch pipe, 5—suction main pipe, 6—second connecting pipe, 7—leakage hole, 8—screw Hole, 9—suction tube, 91—first suction tube, 92—second suction tube, 10—suction hole, 101—first suction hole, 102—second suction hole, 11—intubation tube, 12— Sustained-release flushing bag, 121—middle bag, 122—first side bag, 123—second side bag, 13—first one-way valve.

detailed description

According to the above technical scheme, as shown in Figures 1 to 5, a drug-loaded slow-release, flushing and negative pressure suction steel plate of the present invention includes a steel plate 1, and screw holes 8 are distributed on the steel plate 1; the steel plate 1 serves as The implant is implanted into the patient's body, the bone nail is screwed in through the screw hole 8, and the broken ends of the fracture site are fixed together by the steel plate 1.

The interior of the steel plate 1 is distributed with a flushing branch pipe 4 and a suction pipe 9, wherein the flushing branch pipe 4 is connected to the flushing main pipe 2, the suction pipe 9 is connected to the suction main pipe 5, and both the flushing main pipe 2 and the suction main pipe 5 pass through the upper surface of the steel plate 1; The upper surface of the steel plate 1 is distributed with leakage holes 7 communicating with the flushing branch pipe 4 , and the upper surface of the steel plate 1 and the side of the steel plate 1 are distributed with suction holes 10 communicating with the flushing branch pipe 4 .

In this solution, the liquid leakage hole 7 has multiple functions, for example, antibiotic particles can be preset in the liquid leakage hole 7, and when the wound surface needs to be sterilized, the medicine can be pushed to the wound surface through gas or liquid to achieve local anti-inflammation; and Leakage hole 7 can also be used as a liquid outlet when cleaning the wound surface. Use the main flushing pipe 2 to connect to the flushing system. When necessary, the wound is flushed, and the flushing liquid is sucked out by the main suction pipe 5 to form a circulation system. The suction holes 10 are distributed on the upper surface and the side of the steel plate 1, and the wound area liquid can be extracted by using the suction holes 10, and the wound surface can also be circulated and rinsed with the flushing main pipe 2.

In order to better cooperate with the above-mentioned drug release and flushing functions, the drug-loaded slow-release, flushing and negative pressure suction steel plate in this plan also includes a slow-release flushing bag 12, and the interior of the slow-release flushing bag 12 is divided into two parts by two partitions. The first side bag 122 on the side, the second side bag 123 and the middle bag 121 in the middle, wherein the first check valve 13 is arranged on the two partitions, and the first check valve 13 only allows the fluid to flow from the first side bag. 122 or the second side bag 123 flows into the middle bag 121; the middle bag 121 is provided with an intubation tube 11 matched with the flushing main pipe 2, and a second one-way valve is arranged in the intubation tube 11.

The slow-release flushing bag 12 and the steel plate 1 are of a detachable structure, and can be plugged and unplugged with the flushing main pipe 2 through the intubation tube 11 . The sustained-release flushing bag 12 is a soft bag, for example, an air bag made of rubber. The purpose of arranging the three capsules is to push the medicine at different times after the steel plate 1 is placed, so as to facilitate the gradual and sustained release of the medicine. The volumes (volumes) of the three capsules can be the same or different. When the volume is the same, a certain amount of medicine can be released to the wound each time. The fluid mentioned above refers to liquid or gas.

In the embodiment shown in FIG. 1 , a preferred steel plate 1 structure is shown. Wherein: the suction tube 9 is distributed at the edge of the steel plate 1, forming a closed loop; the suction tube 9 at the edge can better realize suction and recovery of effusion and flushing fluid. The flushing branch pipes 4 are distributed on both sides of the screw holes 8 .

Further, the steel plate 1 has a rectangular structure, the flushing main pipe 2 is located at the center of the upper surface of the steel plate 1, and the flushing branch pipes 4 are distributed along the length direction of the steel plate 1 on both sides of the flushing main pipe 2, and finally pass through the first The guide tube 3 is connected to the flushing main pipe 2 ; the suction tube 9 is finally connected to the suction main pipe 5 through the second guide tube 6 . In order to facilitate the formation of a circuit when flushing the wound surface, in this solution, two main suction pipes 5 are arranged symmetrically on both sides of the main flushing pipe 2 .

As shown in Figures 1 to 4, the suction pipe 9 includes a first suction pipe 91 and a second suction pipe 92, wherein the first suction pipe 91 is distributed on the edge of the steel plate 1 in the longitudinal direction, and the second suction pipe 92 is distributed on the edge of the steel plate 1. At the edge in the width direction, the ends of the first suction pipe 91 and the second suction pipe 92 communicate with each other, and both pass through the side surface or end surface of the steel plate 1 . The suction hole 10 includes a first suction hole 101 and a second suction hole 102, wherein the first suction hole 101 is distributed on the edge of the upper surface of the steel plate 1, and the second suction hole 102 is distributed on the side and end surface of the steel plate 1 , the first suction hole 101 and the second suction hole 102 are all in communication with the first suction pipe 91 or the second suction pipe 92; taking the first suction hole 101 as an example, the one located on one side of the upper surface in the longitudinal direction The first suction hole 101 communicates with the first suction pipe 91 , and the first suction hole 101 on one side in the width direction communicates with the second suction pipe 92 .

When the device is in use, antibiotic solution of predetermined concentration can be stored in advance in the flushing main pipe 2 and the flushing branch pipe 4. After the fracture fixation wound is completely closed, the whole device is inside the tissue, and the slow-release flushing bag 12 is pressed three times after the operation. Press the middle capsule 121 once, and then press the first side capsule 122 and the second side capsule 123 twice. When the three capsules have the same volume, the antibiotic solution can be squeezed to the wound surface in equal volume during the three extrusion processes. middle. This method does not require systemic application of antibiotics, and the effective concentration of the drug can be achieved locally, and the drug can be released slowly in stages.

If there are signs of infection during the fracture healing period, a 2 cm minimally invasive incision can be made, the slow-release irrigation bag 12 is removed, the external negative pressure drainage irrigation system is connected with the irrigation main pipe 2 and the suction main pipe 5, and the necrotic tissue near the implant, Pus, tissue exudate, etc. are drained out of the body, and physiological saline, disinfectant, etc. can be poured into the flushing port for flushing, and the suction main pipe 5 then drains the flushing liquid out of the body again, thereby forming a circulatory system.

The device is easy to operate and can reduce the number of operations. The drug-loaded slow-release, flushing and negative pressure suction plate was implanted in the first operation, and the plate 1 was removed in the second operation after infection control and fracture healing. There were 2 operations in total, and 1 implant was implanted. The conventional clinical treatment process for implant infection: ① Take out the implant, implant antibiotic bone cement, and temporarily fix it with an external fixator (the first operation); ② After the infection is well controlled, remove the antibiotic bone cement and remove the external fixator. Re-implantation of internal fixation (second operation); ③Because the patient may develop chronic osteomyelitis, the implant needs to be removed again after the fracture heals. A total of 3 operations, 2 implant implants, 1 bone cement implantation, and 1 exoskeleton fixation.

Claims (7)

1. screw hole is distributed with a kind of carried medicine sustained-release, flushing and vacuum suction steel plate, including steel plate (1), described steel plate (1) (8), it is characterised in that flushing is distributed with inside described steel plate (1) and is in charge of (4) and suction tube (9), it is in charge of wherein rinsing (4) flushing house steward (2) is connected to, suction tube (9) is connected to suction house steward (5), rinses house steward (2), suction house steward (5) and pass Steel plate (1) upper surface；

The upper surface of described steel plate (1) is distributed with is in charge of the liquid-leaking nozzle (7) that (4) are connected with the flushing, in steel plate (1) upper table Face and steel plate (1) are distributed with sideways is in charge of the suction hole (10) that (4) are connected with the flushing.

2. carried medicine sustained-release as claimed in claim 1, flushing and vacuum suction steel plate, it is characterised in that described carried medicine sustained-release, Rinse and vacuum suction steel plate also include a sustained release and rinses capsule (12), sustained release rinse capsule (12) it is internal by two separates into For the intermediate bladder (121) of the first side capsule (122), the second side capsule (123) and middle part of both sides, wherein being all provided with two partitions The first check valve (13) is equipped with, the first check valve (13) only allows fluid to be flowed into from the first side capsule (122) or the second side capsule (123) To intermediate bladder (121)；The intubation (11) with described flushing house steward (2) cooperation, intubation are provided with described intermediate bladder (121) (11) the second check valve is provided with.

3. carried medicine sustained-release as claimed in claim 1, flushing and vacuum suction steel plate, it is characterised in that described suction tube (9) The edge of steel plate (1) is distributed in, in closed-loop path；The both sides that (4) are distributed in the screw hole (8) are in charge of in described flushing.

4. carried medicine sustained-release as claimed in claim 1, flushing and vacuum suction steel plate, it is characterised in that described steel plate (1) is Cuboid structure, described flushing house steward (2) is located at steel plate (1) upper surface center, and described flushing is in charge of (4) and is rinsing total Length direction distribution of (2) both sides along steel plate (1) is managed, and connecting leg (3) is led eventually through first and is connected to described flushing house steward (2)。

5. carried medicine sustained-release as claimed in claim 1, flushing and vacuum suction steel plate, it is characterised in that described suction tube (9) Including the first suction tube (91) and the second suction tube (92), wherein the first suction tube (91) is distributed in steel plate (1) length direction Edge, the second suction tube (92) is distributed in the edge of steel plate (1) width, the first suction tube (91), the second suction tube (92) end connection, and pass side or the end face of steel plate (1).

6. carried medicine sustained-release as claimed in claim 1, flushing and vacuum suction steel plate, it is characterised in that described suction hole (10) the first suction hole (101) and the second suction hole (102) are included, wherein the first suction hole (101) is distributed in steel plate (1) At top surface edge, the second suction hole (102) is distributed on steel plate (1) side and end face, the first suction hole (101), second Suction hole (102) is connected with described the first suction tube (91) or the second suction tube (92).

7. carried medicine sustained-release as claimed in claim 2, flushing and vacuum suction steel plate, it is characterised in that the first described side capsule (122), the second side capsule (123) and intermediate bladder (121) volume are identical, and are air bag.