CN106730360B - A kind of internal deep therapy instrument - Google Patents
A kind of internal deep therapy instrument Download PDFInfo
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- CN106730360B CN106730360B CN201611270074.2A CN201611270074A CN106730360B CN 106730360 B CN106730360 B CN 106730360B CN 201611270074 A CN201611270074 A CN 201611270074A CN 106730360 B CN106730360 B CN 106730360B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/004—Magnetotherapy specially adapted for a specific therapy
- A61N2/006—Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue
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Abstract
本发明提供一种体内深部治疗仪，其包括可植入体内并用于产生磁场的柔性体、与该柔性体连接的能量源及控制装置，控制装置与能量源连接，柔性体包括液态金属和封装体，液态金属密封在封装体内。本发明提供了一种结构简单、舒适度高且治疗效果好的体内深部治疗仪，以解决现有精神疾病治疗中治疗效果差、舒适度不高的缺陷。
The present invention provides a deep treatment apparatus in the body, which includes a flexible body that can be implanted into the body and used to generate a magnetic field, an energy source and a control device connected to the flexible body, the control device is connected to the energy source, and the flexible body includes liquid metal and a package. body, the liquid metal is sealed in the package. The invention provides a deep body therapy device with simple structure, high comfort and good therapeutic effect, so as to solve the defects of poor therapeutic effect and low comfort in the existing mental disease treatment.
Description
Technical field
The present invention relates to health care equipment technology fields, more particularly, to a kind of internal deep therapy instrument.
Background technique
With the increasing of society's existence and competitive pressure, many people cause many nerves because of work, pressure of study etc.
With spiritual disease, such as depression, stress, anxiety disorder and sleep disturbance.
According to the statistics of the World Health Organization, depression has become the fourth-largest illness in the world, is likely to become and is only second to the year two thousand twenty
The cardiopathic second largest disease.Conservative estimation, the whole world share 3.5 hundred million patients with depression.Depression is in global morbidity
Rate is about 11%, has 15% suicide can be selected to carry out end lives in serious patient, and 2/3 patient once had the thought of suicide,
Every year because the Population size estimation of depression committed suicide is up to 1,000,000.The disease incidence of Chinese depression is 6% or so, by this calculating
There are nearly 90,000,000 patients with depression in China.But since the public is insufficient to the understanding of depression, the Chinese Spirit medical unit 5 in addition
Strength it is insufficient, only 10% patients with depression obtains medical treatment, and remaining 90% about 80,000,000 people is at that " self is supported
It is imperial " state in, China has 250,000 people to die of suicide every year, and 2,000,000 people attempt to commit suicide.
And currently, for mental disease, if the treatment of depression is substantially based on drug and psychotherapy, and be
It is carried out under the background of medical treatment.Although relatively preferable by drug therapy anti-mental disorder effect, there are side effects
Defect.And psychotherapy is although without side-effects, still, therapeutic effect is extremely limited, therefore finds a kind of essence without side-effects
Refreshing disease treatment method become at present treatment mental disease there is an urgent need to.
With the development of science and technology, cranium Neural stem cell (TMS) has been widely used among the treatment of mental disease, and is produced
Raw good mental disease therapeutic effect.Wherein, cranium Neural stem cell is a kind of cortical stimulation method, magnetic signal can undamped ground thoroughly
It crosses skull and stimulates cerebral nerve, be not limited to the stimulation of brains in practical application, peripheral nerve muscle equally can be into
It assassinates and swashs, therefore all cry it for " Neural stem cell " now.Neural stem cell is a kind of physical stimulation form, it is flowed into using changing currents with time
Cerebral magnetic stimulation coil, generates high-intensitive time-varying pulsed magnetic field, and time-varying pulsed magnetic field generates induction field within the organization and inducts
Electric current, induced current make certain excitable tissues generate a kind of excited stimulating method, have it is painless, not damaged, easy to operate,
The advantages that safe and reliable, has a wide range of applications in terms of clinical medicine.
Although this transcranial magnetic stimulation has more significant effect on treatment mental disease, it there is one
A problem is exactly energy dropoff with the intensification for the treatment of site depth, causes cerebral deep tissue that cannot be controlled well
It treats.
In order to solve the above technical problems, one kind is supplied in Chinese patent CN201320100705.1 by shell
The internal magnet therapeutic apparatus that magnetic line of force generator and connecting line in the inner are constituted is filled, although magnet therapeutic apparatus can be installed in body by the device
Power carries out magnetic therapy to patient part using the magnetic line of force launched, and still, since the shell is in hard shape, leads to it in vivo
In use, user experience is poor, especially in the treatment of mental disease, due to its form, it is caused to cannot achieve inside it
Implantation.
Summary of the invention
The present invention provides the internal deep therapy instrument that a kind of structure is simple, comfort level is high and therapeutic effect is good, existing to solve
There is the defect that therapeutic effect is poor, comfort level is not high in mental disease treatment.
According to an aspect of the present invention, a kind of internal deep therapy instrument is provided comprising in an implantable and be used for
The flexible body for generating magnetic field, the energy source and control device connecting with the flexible body, the control device and the energy source connect
It connecing, the flexible body includes liquid metal and flexible encapsulation, and the flexible encapsulation inner surface is equipped with spiral channel,
The liquid metal is encapsulated in the channel, and is equipped with connector in the channel, and the inner surface of the flexible encapsulation is also set
There is the groove body being connected to the endpoint in the channel, is equipped with the first flexible wire in the groove body, and be connected in the connector position
The second flexible wires conducting wire connecting with the energy source, the flexible body pass through first flexible wire and the second flexible wire
It is electrical connected with the control device.
On the basis of above scheme preferably, the liquid metal is the alloy of gallium indium tin.
On the basis of above scheme preferably, the flexible body is cylindrical or patch shape is to implant.
On the basis of above scheme preferably, the liquid metals is GaIn24.5, the GaIn24.5For the conjunction of gallium and indium
The mass ratio of gold, the gallium and indium is 75.5:24.5.
On the basis of above scheme preferably, first flexible wire includes flexible cover and liquid metal, described
Liquid metal is encapsulated in the flexible cover.
On the basis of above scheme preferably, the flexible encapsulation and flexible cover are PDMS.
On the basis of above scheme preferably, the energy source is AC power source, and the voltage that the AC power source generates is
0.1V-36V。
On the basis of above scheme preferably, one is additionally provided between the energy source and control device to adjust the energy
Source exports size of current to change the processing module of magnetic field strength.
On the basis of above scheme preferably, the control device and the processing module pass through bluetooth, infrared or wireless
Electricity is connected by communication.
The application proposes a kind of internal deep therapy instrument, using the electric conductivity of liquid metal, by flexible package body
The channel of setting forms flexible body to realize that the helical form disk of liquid metal is folded, so as to flow through liquid metal by control
Size of current and frequency generate the effect in magnetic field in flexible body, reach to human body deep tissue such as head, back, in body cavity
Intestinal tract, nerve, muscle, the effect of bone etc. magnetic therapy are improved with realizing the purpose for the treatment of nerve and psychosis
Sleep quality relieves pain, and alleviates muscular tone, accelerates local blood circulation, accelerates the treatment such as intestines peristalsis and adjuvant treatment
Purpose.
Since the present invention has good mobility and flexible encapsulation, the first flexible wire, second using liquid metal
The high flexibility of flexible wire improves the comfort level of therapeutic equipment implantation human body of the invention, to realize what therapeutic equipment implanted
Purpose, to increase its therapeutic effect.
Detailed description of the invention
Fig. 1 is a kind of line schematic diagram of internal deep therapy instrument of the invention
Fig. 2 is the schematic diagram that flexible body of the invention is implanted into cerebral cortex；
Fig. 3 is that flexible body of the invention is implanted into subcutaneous backbone schematic diagram in the vicinity；
Fig. 4 is the schematic diagram that flexible body of the invention is implanted into around abdominal cavity intestinal tissue.
Specific embodiment
With reference to the accompanying drawings and examples, specific embodiments of the present invention will be described in further detail.Implement below
Example is not intended to limit the scope of the invention for illustrating the present invention.
Refering to Figure 1, a kind of internal deep therapy instrument of the invention, including in an implantable and for generating magnetic
The flexible body of field, the energy source 4 and control device connecting with the flexible body, control device are connect with energy source 4, and flexible body includes
One liquid metal 1 and a packaging body 2, liquid metal 1 are sealed in packaging body 2, and flexible body passes through conducting wire 3 and energy source electrical property phase
Even.
Wherein, flexible encapsulation inner surface of the invention is equipped with spiral channel, and liquid metal is encapsulated in the channel
It is interior, and it is equipped with connector in the channel, and the inner surface of flexible encapsulation is additionally provided with the groove body being connected to the endpoint in channel, groove body
It is inside equipped with the first flexible wire, and is connected with the second flexible wires conducting wire connecting with energy source in the connector position, flexible body is logical
It crosses the first flexible wire and the second flexible wire is electrical connected with control device.
The present invention has good mobility using liquid metal, can need to mould different moulding according to different, meet
The needs to implant, meanwhile, using flexible encapsulation of the invention, the high flexibility of the first flexible wire, the second flexible wire,
To improve the comfort level that the present invention implants, thus to improve therapeutic effect of the invention.
In use, changing the shape of flexible body according to the position specifically treated, as flexible body is designed to winding tissue
The patch shape of formula or spiral cylindrical is to implant.After implanting, only reserve two conducting wires 3 be connected in vitro, with
Energy source 4 is electrical connected, to provide operating current by energy source 4 for flexible body, to generate magnetic field.By caused by flexible body
Magnetic field is to achieve the purpose that directly to treat pathological tissues.Preferably, which is liquid metal conducting wire.
Such as be implanted into cerebral cortex, can excited deep brain area neuron, adjust the release strength of neurotransmitter, intracerebral
The effects of concentration of neuromodulator, has the function that treat the nervous system disease, such as alleviates depression, improve sleep etc., such as Fig. 2 institute
Show.If being implanted in peripheral nerve, the position of musculature or neuromuscular contact generates a certain amount of magnetic field at the position,
DOMS and chronic pain head and postoperative pain can be alleviated, even elimination swelling improves tissue cell activity and enhancing people
The effect of body immunity, as shown in Figure 3.If being implanted in around enteron aisle, the nerve that stimulation is connected with enteron aisle may can be passed through
Activity generates the effect for promoting intestines peristalsis, as shown in Figure 4.
A kind of internal deep therapy instrument of the invention, the generation body using liquid metal 1 as magnetic field utilize liquid metal
1 liquid fluidity can and good thermal conductivity, flexible body can be designed to different shape, different size of magnetic field generating body,
To meet the needs of implantation human body.Meanwhile the high fluidity energy being had using liquid metal 1, to improve relaxing for implantation human body
Appropriateness.
The present invention provides a kind of comfort level high internal deep therapy instrument, compared with traditional external flexible body treatment,
Since it is implanted in inside of human body pathological tissues portion, caused by can effectively overcoming traditional external flexible body treatment magnetic field weak
The defect of therapeutic effect difference, is greatly improved its therapeutic effect.
As the first preferred embodiment of the invention, energy source 4 of the invention is AC power source, and the AC power source
Operating voltage be 0.1V-36V guarantee the safety of human body therapy that is, while guaranteeing its therapeutic effect.
As second of preferred embodiment of the invention, it is gallium indium tin that liquid metal 1 of the invention, which is liquid metal,
Alloy or gallium-indium alloy, it is preferred that liquid metals of the invention is GaIn24.5, and GaIn24.5For the alloy of gallium and indium, described in
The mass ratio of gallium and indium is 75.5:24.5
As second of preferred embodiment of the invention, packaging body 2 of the invention be with biocompatibility well and not
The PDMS reacted with liquid metal 1.By packaging body 2 seal liquid metal 1, prevent liquid metal 1 directly with in-vivo tissue phase
Contact generates adverse reaction, and plays the form of fixed liquid metal 1, to meet the needs of different therapentic parts.
As the third preferred embodiment of the invention, in order to realize the volume adjusting to internal magnetic field size.The present invention
One is additionally provided between energy source 4 and control device to adjust the energy source 4 output size of current to change magnetic field strength
Processing module 6.The processing module 6 is used for the control signal of receiving control device, converts the control signal to and is used to control energy
The electrical control signals in amount source 4, the signal frequency and intensity issued by control energy source 4 are produced with reaching change flexible body
The purpose of the intensity size of magnetisation field.
For the ease of being routed and using, control device of the invention and the processing module 6 preferably by bluetooth, it is infrared or
Radio communication is connected.
For the technical solution that present invention be described in more detail, use process of the invention will be detailed below:
1. clinician does conventional pre-operative preparation, sterilization of instruments etc..
2. planned the form of the magnetic therapy material in implantation, such as patch type or cylindric.Material is implanted into
Patient's privileged site, and continue to monitor patient body temperature and various physical signs.
3. being connected two liquid metal conducting wires are reserved in vitro and with external power supply and signal processing module.
4. may be implemented in the electromagnetic field that deep tissue generates appropriate intensity by control module.
5. if please being stopped using immediately patient generates any discomfort reaction.
The application proposes a kind of internal deep therapy instrument, and the size of current and frequency of liquid metal 1 are flowed through by controlling, can
It realizes the effect for generating space magnetic field, reaches to human body deep tissue such as head, back, intestinal tract in body cavity, nerve, flesh
Meat, the effect of bone etc. magnetic therapy reach treatment nerve and psychosis, improve sleep quality, relieve pain, alleviate flesh
Meat is nervous, accelerates local blood circulation, accelerates the purpose of the treatment and adjuvant treatment such as intestines peristalsis.
Finally, the present processes are only preferable embodiment, it is not intended to limit the scope of the present invention.It is all
Within the spirit and principles in the present invention, any modification, equivalent replacement, improvement and so on should be included in protection of the invention
Within the scope of.
Claims (9)
Priority Applications (1)
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| CN201611270074.2A CN106730360B (en) | 2016-12-30 | 2016-12-30 | A kind of internal deep therapy instrument |
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| CN201611270074.2A CN106730360B (en) | 2016-12-30 | 2016-12-30 | A kind of internal deep therapy instrument |
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| CN106730360B true CN106730360B (en) | 2019-03-01 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108057173A (en) * | 2017-12-08 | 2018-05-22 | 丰润（泉州）健康科技有限公司 | A kind of physical therapy device and its processing technology |
| CN109330642B (en) * | 2018-08-03 | 2020-05-01 | 云南靖创液态金属热控技术研发有限公司 | Auxiliary stretching device for endoscopic surgery |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105658272A (en) * | 2013-09-06 | 2016-06-08 | Med-El电气医疗器械有限公司 | Cochlear implant electrode with liquid metal alloy |
| CN105944228A (en) * | 2016-04-25 | 2016-09-21 | 清华大学 | Implanted flexible neural electrode based on liquid metal and production method |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20150080637A1 (en) * | 2013-09-16 | 2015-03-19 | The General Hospital Corporation | Microscopic magnetic coils for neural stimulation |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105658272A (en) * | 2013-09-06 | 2016-06-08 | Med-El电气医疗器械有限公司 | Cochlear implant electrode with liquid metal alloy |
| CN105944228A (en) * | 2016-04-25 | 2016-09-21 | 清华大学 | Implanted flexible neural electrode based on liquid metal and production method |
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