CN106728641A - It is a kind of to treat medicine of headache and preparation method thereof - Google Patents
It is a kind of to treat medicine of headache and preparation method thereof Download PDFInfo
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- A61K2236/30—Extraction of the material
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Abstract
Medicine of headache and preparation method thereof is treated the invention discloses a kind of, it is mainly and is prepared from according to a certain weight ratio by Radix Angelicae Sinensis, radix rehmanniae recen, peach kernel, safflower, Fructus Aurantii, the radix paeoniae rubrathe, radix bupleuri, Radix Glycyrrhizae, rascal, medicine of the present invention has benefiting blood and regulating blood circulation, moisturize laxation, regulating the flow of vital energy Xie Yu, soothing the liver relieving stagnant Qi, with middle emergency, the function of dispelling wind and removing obstruction in the meridians, for treating headache instant effect, good effect, does not recur.
Description
Technical field
Medicine of headache and preparation method thereof is treated the present invention relates to a kind of, belongs to the field of Chinese medicines.
Technical background
Headache is clinical common symptom, generally be will be limited to grand outside the head first half, including geisoma, helix upper limb and pillow
Prominent line causes headache to have many reasons with the pain of upper bit.The traditional Chinese medical science then thinks headache with exopathogen invasion, stagnation of liver qi, feelings
Will is disgruntled, eating and drinking without temperance, yin channel consume, and qi and blood is decayed relevant.Because western medicine side effect is big, therefore people are to effectively treatment
There is great demand in the Chinese medicine of headache, up to now, it has not been found that on relevant report of the invention.
The content of the invention
The present inventor have found effectively treatment headache finally according to the checking repeatedly of research and the clinical test of theory of traditional Chinese medical science
Medicine, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of effective treatment headache.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention be selection Radix Angelicae Sinensis, radix rehmanniae recen, peach kernel, safflower, Fructus Aurantii, the radix paeoniae rubrathe, radix bupleuri, Radix Glycyrrhizae, rascal, rhizoma cyperi,
The root of bidentate achyranthes, scorpio medicine are combined preparation, and these drug regimens are caused into each efficacy of drugs produces synergy such that it is able to
Effectively treatment headache.Wherein there is benefiting blood and regulating blood circulation because its nature and flavor sweet, acrid, warm, enters the heart, liver, the spleen channel from Radix Angelicae Sinensis, menstruation regulating stops
Bitterly, the function of moisturize laxation, controls irregular menstruation, and Amenorrhea stomachache , Disorder lumps in the abdomen knot gathers, and uterine bleeding, headache due to deficiency of blood, dizziness, Impotence numbness, intestinal dryness is difficult
Just, weight, ulcer sores, metal-inflicted wound, injury from falling down after dysentery characterized by blood in the stool.From radix rehmanniae recen because its nature and flavor is sweet, tremble with fear, the thoughts of returning home, liver and kidney channel,
There is clearing heat and cooling blood, yin-nourishing, the function of promoting the production of body fluid controls pyreticosis polydipsia, and yin asthenia generating intrinsic heat, hectic fever due to yin labor heat, Heat Diabetes is spitted blood, bleeding from five sense organs or subcutaneous tissue, hair
Spot dermexanthesis.From peach kernel because its nature and flavor bitter sweet, puts down, enter the heart, liver, large intestine channel, there is the blood-breaking row stasis of blood, moisturize the function of sliding warp,
Controlling through closing , Disorder lumps in the abdomen, pyreticosis stores blood, blood-arthralgia, malaria, traumatic injury, blood stasis and swelling pain, the dry constipation of blood.From safflower because its property
Taste is pungent, temperature, enters the heart, Liver Channel, there is invigorate blood circulation, and the function of stasis eliminatings analgesic, controlling through closing , Disorder lumps in the abdomen are had difficult labour, stillborn foetus, and lochia is not
OK, hemostasis is had a pain, carbuncle swells, injury from falling down.From Fructus Aurantii because its nature and flavor toil, cool, enter lung, spleen, large intestine channel, there is relieving stagnant Qi,
Row phlegm, the function of disperse accumulations, it is stagnant to control chest diaphragm phlegm, the feeling of stuffiness in chest, coerces swollen, dyspepsia, and gas is vomitted inverse, weight, prolapse of the anus, the prolapse of uterus after diarrhea.Choosing
With the radix paeoniae rubrathe because its is bitter in taste, it is slightly cold, return liver warp has clearing heat and cooling blood, and the function of blood stasis removing analgesic is controlled epidemic heat syndrome and gone mad, nosebleed of spitting blood
Blood, red eye, swell pain, liver-depressed hypochondrium pain, closed dysmenorrhea , Epilepsy lump in the abdomen stomachache, injury from falling down, carbuncle swells sore.From radix bupleuri because its nature and flavor
Hardship, cool, enter liver, gallbladder channel have with inducing diaphoresis, and soothing the liver, the function of rising Yang controls fevers and chills alternate, and fullness in the chest and hypochondriac pain, bitter taste is deaf, headache
It is dizzy, malaria, lower sharp prolapse of the anus, irregular menstruation, metroptosis.From Radix Glycyrrhizae because its property sweet taste, enters spleen, stomach, lung channel, have
With middle emergency, moistening lung, removing toxic substances, the function of coordinating the drug actions of a prescription processs, deficiency of food weakness of the spleen and the stomach with controlling, and loose stool of suffering from abdominal pain, overstrain generates heat, consumptive lung disease
Cough, palpitaition shies carbuncle, raw with controlling abscess of throat, peptic ulcer, ulcer sores, antidote poison and poisons by food.It is from rascal
Because its nature and flavor toil, tepor, enter liver, gallbladder channel, there is a soothing the liver relieving stagnant Qi, the function of dissipating bind dissolving phlegm controls chest side of body gastral cavity pain, hernia,
Dyspepsia, breast is swollen, newborn core, chronic malaria addiction block.From rhizoma cyperi because the pungent slight bitter of its nature and flavor is dry, put down, enter liver, tri-jiao channel have qi-regulating solution
It is strongly fragrant, the function of menstruation regulating is relieved pain, control liver-stomach disharmony, depression of QI, the chest and abdomen distending pain in hypochondrium, phlegm and retained fluid feeling of fullness, irregular menstruation, uterine bleeding band
Under.From the root of bidentate achyranthes because its nature and flavor sweetness and bitterness is sour, put down, enter liver and kidney channel, life scattered blood stasis, the function of subduing inflammation controls gonorrhoea, urine
Blood, Amenorrhea , Disorder lumps in the abdomen, difficult labour, placenta retension, postpartum blood stasis stomachache, larynx numbness, carbuncle swells, traumatic injury, ripe use filling liver kidney, strengthening the bones and muscles,
Control control waist and knee ostalgia, spasm of limbs, Impotence numbness.From scorpio because its nature and flavor is salty pungent, put down, it is poisonous, there is wind-dispelling, only convulsion, dredging collateral, solution
The function of poison, controls convulsion , Dian Epilepsy, and apoplexy, hemiplegia, Kou Yan wo are oblique, antimigraine, arthralgia pain due to rheumatism, lockjaw, lymph node
Tuberculosis, rubella sore swells.
Specific embodiment
The drug dose of instant component is also that inventor summarizes what is drawn by largely groping, and the consumption of each component is following heavy
All there is preferable curative effect in the range of amount：
10-20 grams of Radix Angelicae Sinensis, 10-20 grams of radix rehmanniae recen, 15-25 grams of peach kernel, 10-20 grams of safflower, 5-15 grams of Fructus Aurantii, 5-15 grams of the radix paeoniae rubrathe,
3-7 grams of radix bupleuri, 3-7 grams of Radix Glycyrrhizae, 5-15 grams of rascal, 5-15 grams of rhizoma cyperi, 10-20 grams of the root of bidentate achyranthes, 5-8 grams of scorpio.
Preferably：
15 grams of Radix Angelicae Sinensis, 15 grams of radix rehmanniae recen, 20 grams of peach kernel, 15 grams of safflower, 10 grams of Fructus Aurantii, 10 grams of the radix paeoniae rubrathe, 5 grams of radix bupleuri, 5 grams of Radix Glycyrrhizae,
10 grams of rascal, 10 grams of rhizoma cyperi, 15 grams of the root of bidentate achyranthes, 6 grams of scorpio.
The preparation method of medicine of the present invention is as follows
First, get the raw materials ready
1st, Radix Angelicae Sinensis：Impurity is picked, is cleaned, vexed profit is slightly dried in the air, and section is dried；
2nd, radix rehmanniae recen：Impurity is removed, is cleaned, slightly moistened, cut sheet, dried, weed out chip；
3rd, peach kernel：Remove duricrust impurity, put boiling water pot in boil to crust microcreping, pull out, immersion cold water in, stranding remove kind of a skin, dry,
Winnow with a dustpan net；
4th, safflower：Net impurity is picked, cauline leaf, base of a fruit head is removed, dried；
5th, Fructus Aurantii：Flesh, core are removed, edulcoration slightly soaks, pulls out, softens, pinching doubling with hand, section is dried；
6th, the radix paeoniae rubrathe：Crude drug is taken, impurity is removed, size stepping is cleaned, run through, shave, dries, and weeds out chip；
7th, radix bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, pulled out, section in time, dries immediately after running through；
8th, Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, dry；
9th, rascal：Net impurity is picked, is soaked in water, pulled out, run through, cut into slices, dried；
10th, rhizoma cyperi：Impurity is picked, particle is ground into, winnow with a dustpan fine, soft fur and smalls；
11st, the root of bidentate achyranthes：Impurity is picked, is cleaned, softened, go reed, segment is dried；
12nd, scorpio：Clear water floats the matter that desalts, and dries, or low baking temperature roasting is used.
2nd, prepare
1st, by the Radix Angelicae Sinensis after processing, radix rehmanniae recen, peach kernel, safflower, Fructus Aurantii, the radix paeoniae rubrathe, radix bupleuri, Radix Glycyrrhizae, rascal, rhizoma cyperi, the root of bidentate achyranthes, scorpio
It is put into decocting container, adds water for the first time 6 times and measure, after immersion 100 minutes, fries by intense fire to boil and rise, then with being cooked by slow fire 20 minutes,
First time decoction liquor is filtered to obtain, first time decoction liquor is poured into container；
2nd, the dregs of a decoction of filtering are added into 4 times of amounts, is boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor；
3rd, will decoction liquor mixing and stirring twice, be divided into 2 doses and take.
Radix Angelicae Sinensis has a benefiting blood and regulating blood circulation in prescription, menstruction regulating and pain relieving, and the function of moisturize laxation is monarch drug in a prescription；Rhizoma cyperi regulating the flow of vital energy Xie Yu, controls liver
Stomach is got along well, depression of QI；Rascal has a soothing the liver relieving stagnant Qi, the function of dissipating bind dissolving phlegm, and the two is ministerial drug, three taste medicines play jointly enrich blood and
Blood, menstruction regulating and pain relieving, regulating the flow of vital energy Xie Yu, soothing the liver relieving stagnant Qi, the effect of dissipating bind dissolving phlegm, treatment headache effect comprehensively, and with benefiting blood and regulating blood circulation, is managed
Gas solution is strongly fragrant, can be effected a permanent cure based on soothing the liver relieving stagnant Qi, and scorpio has wind-dispelling, only convulsion, dredging collateral, and the function of removing toxic substances is adjutant, and Radix Glycyrrhizae has delays with
It is anxious, moistening lung, removing toxic substances, the function of coordinating the drug actions of a prescription, to make medicine, is to take stopgap measures with remaining all medicines.
Medicine of the present invention has benefiting blood and regulating blood circulation, moisturize laxation, regulating the flow of vital energy Xie Yu, soothing the liver relieving stagnant Qi, and middle emergency, dispelling wind and removing obstruction in the meridians
Function, has a headache for treating, short treating period, instant effect, non-relapse after healing.
Specific embodiment：
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these test examples include medicine of the present invention
The animal toxicity test report of thing and clinical observation on the therapeutic effect data.
The animal toxicity test report of [test example 1] medicine of the present invention：
Rabbit 30 is taken, male and female dual-purpose, 2.0-2.5kg of body weight is divided to two groups, and every group 15, one of which is tested for overdose
Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is given for administration by gavage
Medicine, twice daily, takes medicine continuously 7 days, the reaction of observation administration daily, as a result shows that two groups of rabbit activities, diet are normal, and medicine is without bad
Toxic and side effect.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1st, physical data
Accept Headache Clinic patient totally 26 for medical treatment.
2nd, diagnostic criteria
Classical symptom is nausea, and vomiting is dizzy, distending pain, vexed pain, the symptom such as head lock ring sense.
3rd, treatment method
From above-mentioned medicament, taken to patient, each take 1 dose, early daily, evening respectively takes 1 time, continuously takes 7 days.
4th, efficacy assessment standard
It is effective：Headache syndromes disappear, and constitution recovers normal, recovery from illness；
Take a turn for the better：Patients ' vomiting, dizzy, the symptom mitigation of head lock ring sense, headache syndromes are clearly better, and constitution is progressively extensive
It is multiple；
It is invalid：Improvement standard person is not reached.
5th, treatment results（See the table below）
In above-mentioned treatment, with drug therapy headache of the present invention 26, as a result effective 21, obvious effective rate is 80.77%, good
Turn 4, improvement rate is 15.38%, and invalid 1, total effective rate is 96.15%.
Claims (3)
1. a kind of medicine for treating headache, it is characterised in that：It is made up of the bulk drug in following weight range：
10-20 grams of Radix Angelicae Sinensis, 10-20 grams of radix rehmanniae recen, 15-25 grams of peach kernel, 10-20 grams of safflower, 5-15 grams of Fructus Aurantii, 5-15 grams of the radix paeoniae rubrathe,
3-7 grams of radix bupleuri, 3-7 grams of Radix Glycyrrhizae, 5-15 grams of rascal, 5-15 grams of rhizoma cyperi, 10-20 grams of the root of bidentate achyranthes, 5-8 grams of scorpio.
2. medicine according to claim 1, wherein the consumption of each bulk drug is：
15 grams of Radix Angelicae Sinensis, 15 grams of radix rehmanniae recen, 20 grams of peach kernel, 15 grams of safflower, 10 grams of Fructus Aurantii, 10 grams of the radix paeoniae rubrathe, 5 grams of radix bupleuri, 5 grams of Radix Glycyrrhizae,
10 grams of rascal, 10 grams of rhizoma cyperi, 15 grams of the root of bidentate achyranthes, 6 grams of scorpio.
3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps：
（One）Get the raw materials ready
（1）Radix Angelicae Sinensis：Impurity is picked, is cleaned, vexed profit is slightly dried in the air, and section is dried；
（2）Radix rehmanniae recen：Impurity is removed, is cleaned, slightly moistened, cut sheet, dried, weed out chip；
（3）Peach kernel：Remove duricrust impurity, put boiling water pot in boil to crust microcreping, pull out, immersion cold water in, stranding remove kind of a skin, shine
It is dry, winnow with a dustpan net；
（4）Safflower：Net impurity is picked, cauline leaf, base of a fruit head is removed, dried；
（5）Fructus Aurantii：Flesh, core are removed, edulcoration slightly soaks, pulls out, softens, pinching doubling with hand, section is dried；
（6）The radix paeoniae rubrathe：Crude drug is taken, impurity is removed, size stepping is cleaned, run through, shave, dries, and weeds out chip；
（7）Radix bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, pulled out, section in time, dries immediately after running through；
（8）Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, dry；
（9）Rascal：Net impurity is picked, is soaked in water, pulled out, run through, cut into slices, dried；
（10）Rhizoma cyperi：Impurity is picked, particle is ground into, winnow with a dustpan fine, soft fur and smalls；
（11）The root of bidentate achyranthes：Impurity is picked, is cleaned, softened, go reed, segment is dried；
（12）Scorpio：Clear water floats the matter that desalts, and dries, or low baking temperature roasting is used；
（Two）Prepare
（1）By the Radix Angelicae Sinensis after processing, radix rehmanniae recen, peach kernel, safflower, Fructus Aurantii, the radix paeoniae rubrathe, radix bupleuri, Radix Glycyrrhizae, rascal, rhizoma cyperi, the root of bidentate achyranthes, complete
Scorpion is put into decocting container, is added water 6 times and is measured, and after soaking 100 minutes, is fried by intense fire to boil and is risen, then with being cooked by slow fire 20 minutes, is filtered
First time decoction liquor is obtained, first time decoction liquor is poured into container；
（2）The dregs of a decoction of filtering are added water 4 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor；
（3）Decoction liquor mixing and stirring twice is incited somebody to action, is divided into 2 doses and is taken.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104758528A (en) * | 2015-03-26 | 2015-07-08 | 孙红梅 | Traditional Chinese medicine composition for treating headache |
Non-Patent Citations (1)
| Title |
|---|
| 周文泉等主编: "《中医老年病临床研究》", 31 July 1995, 北京出版社 * |
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