CN106721422A - The chicken feed of hydroxyl Methionine calcium salt and 25 hydroxycholecalciferols, mixed fodder and application - Google Patents
The chicken feed of hydroxyl Methionine calcium salt and 25 hydroxycholecalciferols, mixed fodder and application Download PDFInfo
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- CN106721422A CN106721422A CN201611075213.6A CN201611075213A CN106721422A CN 106721422 A CN106721422 A CN 106721422A CN 201611075213 A CN201611075213 A CN 201611075213A CN 106721422 A CN106721422 A CN 106721422A
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- 241000287828 Gallus gallus Species 0.000 title claims abstract description 81
- 235000021318 Calcifediol Nutrition 0.000 title claims description 11
- FCNGBJDFPVYGSV-SCGRZTRASA-L calcium;(2s)-2-(hydroxyamino)-4-methylsulfanylbutanoate Chemical compound [Ca+2].CSCC[C@H](NO)C([O-])=O.CSCC[C@H](NO)C([O-])=O FCNGBJDFPVYGSV-SCGRZTRASA-L 0.000 title abstract description 4
- 229930182817 methionine Natural products 0.000 claims abstract description 72
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims abstract description 61
- KIZFHUJKFSNWKO-UHFFFAOYSA-M calcium monohydroxide Chemical compound [Ca]O KIZFHUJKFSNWKO-UHFFFAOYSA-M 0.000 claims abstract description 45
- 238000011161 development Methods 0.000 claims abstract description 8
- 230000037396 body weight Effects 0.000 claims abstract description 7
- 208000021017 Weight Gain Diseases 0.000 claims abstract description 5
- 235000019786 weight gain Nutrition 0.000 claims abstract description 5
- 239000011647 vitamin D3 Substances 0.000 claims description 47
- 235000001465 calcium Nutrition 0.000 claims description 25
- 244000046052 Phaseolus vulgaris Species 0.000 claims description 23
- 235000010627 Phaseolus vulgaris Nutrition 0.000 claims description 23
- 240000008042 Zea mays Species 0.000 claims description 22
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims description 22
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 22
- 235000005822 corn Nutrition 0.000 claims description 22
- 235000013312 flour Nutrition 0.000 claims description 21
- 239000004575 stone Substances 0.000 claims description 21
- 235000012424 soybean oil Nutrition 0.000 claims description 20
- 239000003549 soybean oil Substances 0.000 claims description 20
- 235000013339 cereals Nutrition 0.000 claims description 18
- 235000015099 wheat brans Nutrition 0.000 claims description 17
- 239000011575 calcium Substances 0.000 claims description 16
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 15
- 229910052791 calcium Inorganic materials 0.000 claims description 15
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 12
- JWUBBDSIWDLEOM-XHQRYOPUSA-N (3e)-3-[(2e)-2-[1-(6-hydroxy-6-methylheptan-2-yl)-7a-methyl-2,3,3a,5,6,7-hexahydro-1h-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol Chemical compound C1CCC2(C)C(C(CCCC(C)(C)O)C)CCC2\C1=C\C=C1/CC(O)CCC1=C JWUBBDSIWDLEOM-XHQRYOPUSA-N 0.000 claims description 10
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims description 8
- 235000005911 diet Nutrition 0.000 claims description 8
- 229910052698 phosphorus Inorganic materials 0.000 claims description 8
- 239000011574 phosphorus Substances 0.000 claims description 8
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims description 6
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 claims description 6
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 6
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 6
- 229910021536 Zeolite Inorganic materials 0.000 claims description 6
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims description 6
- 239000000843 powder Substances 0.000 claims description 6
- 239000010457 zeolite Substances 0.000 claims description 6
- 235000019751 broiler diet Nutrition 0.000 claims description 4
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims description 4
- 239000001763 2-hydroxyethyl(trimethyl)azanium Substances 0.000 claims description 3
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 3
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 claims description 3
- 235000019743 Choline chloride Nutrition 0.000 claims description 3
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 3
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 claims description 3
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims description 3
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims description 3
- 229930003427 Vitamin E Natural products 0.000 claims description 3
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 3
- 229960002685 biotin Drugs 0.000 claims description 3
- 235000020958 biotin Nutrition 0.000 claims description 3
- 239000011616 biotin Substances 0.000 claims description 3
- 229960003178 choline chloride Drugs 0.000 claims description 3
- SGMZJAMFUVOLNK-UHFFFAOYSA-M choline chloride Chemical compound [Cl-].C[N+](C)(C)CCO SGMZJAMFUVOLNK-UHFFFAOYSA-M 0.000 claims description 3
- 229910052802 copper Inorganic materials 0.000 claims description 3
- 239000010949 copper Substances 0.000 claims description 3
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 3
- 239000011630 iodine Substances 0.000 claims description 3
- 229910052740 iodine Inorganic materials 0.000 claims description 3
- 229910052742 iron Inorganic materials 0.000 claims description 3
- 239000011572 manganese Substances 0.000 claims description 3
- 229910052748 manganese Inorganic materials 0.000 claims description 3
- 229960003966 nicotinamide Drugs 0.000 claims description 3
- 235000005152 nicotinamide Nutrition 0.000 claims description 3
- 239000011570 nicotinamide Substances 0.000 claims description 3
- 229940055726 pantothenic acid Drugs 0.000 claims description 3
- 235000019161 pantothenic acid Nutrition 0.000 claims description 3
- 239000011713 pantothenic acid Substances 0.000 claims description 3
- 239000011669 selenium Substances 0.000 claims description 3
- 229910052711 selenium Inorganic materials 0.000 claims description 3
- 239000011691 vitamin B1 Substances 0.000 claims description 3
- 239000011715 vitamin B12 Substances 0.000 claims description 3
- 239000011716 vitamin B2 Substances 0.000 claims description 3
- 239000011726 vitamin B6 Substances 0.000 claims description 3
- 235000019165 vitamin E Nutrition 0.000 claims description 3
- 239000011709 vitamin E Substances 0.000 claims description 3
- 229940046009 vitamin E Drugs 0.000 claims description 3
- 239000011652 vitamin K3 Substances 0.000 claims description 3
- 239000011701 zinc Substances 0.000 claims description 3
- 229910052725 zinc Inorganic materials 0.000 claims description 3
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 2
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims description 2
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims description 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 2
- 229960000304 folic acid Drugs 0.000 claims description 2
- 235000019152 folic acid Nutrition 0.000 claims description 2
- 239000011724 folic acid Substances 0.000 claims description 2
- 235000019155 vitamin A Nutrition 0.000 claims description 2
- 239000011719 vitamin A Substances 0.000 claims description 2
- 229940045997 vitamin a Drugs 0.000 claims description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims 2
- MJVAVZPDRWSRRC-UHFFFAOYSA-N Menadione Chemical compound C1=CC=C2C(=O)C(C)=CC(=O)C2=C1 MJVAVZPDRWSRRC-UHFFFAOYSA-N 0.000 claims 1
- 240000007594 Oryza sativa Species 0.000 claims 1
- 235000007164 Oryza sativa Nutrition 0.000 claims 1
- 229910021529 ammonia Inorganic materials 0.000 claims 1
- 235000009566 rice Nutrition 0.000 claims 1
- 239000011782 vitamin Substances 0.000 abstract description 22
- 230000000694 effects Effects 0.000 abstract description 7
- 238000009374 poultry farming Methods 0.000 abstract description 2
- 235000006109 methionine Nutrition 0.000 description 60
- 235000013601 eggs Nutrition 0.000 description 46
- 235000014590 basal diet Nutrition 0.000 description 23
- 239000000047 product Substances 0.000 description 22
- 210000002303 tibia Anatomy 0.000 description 12
- JWUBBDSIWDLEOM-NQZHSCJISA-N 25-hydroxy-3 epi cholecalciferol Chemical compound C1([C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=CC=C1C[C@H](O)CCC1=C JWUBBDSIWDLEOM-NQZHSCJISA-N 0.000 description 10
- 102000002322 Egg Proteins Human genes 0.000 description 9
- 108010000912 Egg Proteins Proteins 0.000 description 9
- 210000003278 egg shell Anatomy 0.000 description 9
- 238000004519 manufacturing process Methods 0.000 description 9
- 229940088594 vitamin Drugs 0.000 description 9
- 229930003231 vitamin Natural products 0.000 description 8
- 235000013343 vitamin Nutrition 0.000 description 8
- 235000021050 feed intake Nutrition 0.000 description 7
- 150000003722 vitamin derivatives Chemical class 0.000 description 7
- 241001465754 Metazoa Species 0.000 description 6
- VZPGZOPEARNTLA-WCCKRBBISA-N calcium;(2s)-2-(hydroxyamino)-4-methylsulfanylbutanoic acid Chemical compound [Ca].CSCC[C@H](NO)C(O)=O VZPGZOPEARNTLA-WCCKRBBISA-N 0.000 description 6
- 230000018109 developmental process Effects 0.000 description 6
- HLBIGQDEEVNODU-RGMNGODLSA-N [Ca].C(CC)N[C@@H](CCO)C(=O)O Chemical compound [Ca].C(CC)N[C@@H](CCO)C(=O)O HLBIGQDEEVNODU-RGMNGODLSA-N 0.000 description 5
- 238000010521 absorption reaction Methods 0.000 description 5
- 210000002966 serum Anatomy 0.000 description 5
- 239000011710 vitamin D Substances 0.000 description 5
- DUAQZVXGEHUXOH-UHFFFAOYSA-N N.[Ca] Chemical compound N.[Ca] DUAQZVXGEHUXOH-UHFFFAOYSA-N 0.000 description 4
- 235000001014 amino acid Nutrition 0.000 description 4
- 150000001413 amino acids Chemical group 0.000 description 4
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- KFSJYZYQSZKRRQ-BYPYZUCNSA-N (2s)-2-(hydroxyamino)-4-methylsulfanylbutanoic acid Chemical compound CSCC[C@H](NO)C(O)=O KFSJYZYQSZKRRQ-BYPYZUCNSA-N 0.000 description 3
- JWUBBDSIWDLEOM-UHFFFAOYSA-N 25-Hydroxycholecalciferol Natural products C1CCC2(C)C(C(CCCC(C)(C)O)C)CCC2C1=CC=C1CC(O)CCC1=C JWUBBDSIWDLEOM-UHFFFAOYSA-N 0.000 description 3
- JWUBBDSIWDLEOM-DCHLRESJSA-N 25-Hydroxyvitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C/C=C1\C[C@@H](O)CCC1=C JWUBBDSIWDLEOM-DCHLRESJSA-N 0.000 description 3
- 239000002207 metabolite Substances 0.000 description 3
- 244000144977 poultry Species 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- WIGIZIANZCJQQY-UHFFFAOYSA-N 4-ethyl-3-methyl-N-[2-[4-[[[(4-methylcyclohexyl)amino]-oxomethyl]sulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide Chemical compound O=C1C(CC)=C(C)CN1C(=O)NCCC1=CC=C(S(=O)(=O)NC(=O)NC2CCC(C)CC2)C=C1 WIGIZIANZCJQQY-UHFFFAOYSA-N 0.000 description 2
- RPHZRUDLEUBFCM-UHFFFAOYSA-L calcium;methanedisulfonate Chemical class [Ca+2].[O-]S(=O)(=O)CS([O-])(=O)=O RPHZRUDLEUBFCM-UHFFFAOYSA-L 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 229960003180 glutathione Drugs 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 230000000474 nursing effect Effects 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 235000018102 proteins Nutrition 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 238000012797 qualification Methods 0.000 description 2
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 2
- BHQCQFFYRZLCQQ-UHFFFAOYSA-N (3alpha,5alpha,7alpha,12alpha)-3,7,12-trihydroxy-cholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)C(O)C2 BHQCQFFYRZLCQQ-UHFFFAOYSA-N 0.000 description 1
- ONFOSYPQQXJWGS-UHFFFAOYSA-N 2-hydroxy-4-(methylthio)butanoic acid Chemical compound CSCCC(O)C(O)=O ONFOSYPQQXJWGS-UHFFFAOYSA-N 0.000 description 1
- PICCHNWCTUUCAQ-UHFFFAOYSA-N 2-hydroxypentanethioic s-acid Chemical class CCCC(O)C(O)=S PICCHNWCTUUCAQ-UHFFFAOYSA-N 0.000 description 1
- 239000004380 Cholic acid Substances 0.000 description 1
- 239000004470 DL Methionine Substances 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 101000693916 Gallus gallus Albumin Proteins 0.000 description 1
- 108010024636 Glutathione Proteins 0.000 description 1
- 102000006587 Glutathione peroxidase Human genes 0.000 description 1
- 108700016172 Glutathione peroxidases Proteins 0.000 description 1
- 108060003951 Immunoglobulin Proteins 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 102000019197 Superoxide Dismutase Human genes 0.000 description 1
- 108010012715 Superoxide dismutase Proteins 0.000 description 1
- 229930003316 Vitamin D Natural products 0.000 description 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 230000010256 bone deposition Effects 0.000 description 1
- 230000014461 bone development Effects 0.000 description 1
- 230000037118 bone strength Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 1
- 239000000920 calcium hydroxide Substances 0.000 description 1
- 229910001861 calcium hydroxide Inorganic materials 0.000 description 1
- BRPQOXSCLDDYGP-UHFFFAOYSA-N calcium oxide Chemical compound [O-2].[Ca+2] BRPQOXSCLDDYGP-UHFFFAOYSA-N 0.000 description 1
- 239000000292 calcium oxide Substances 0.000 description 1
- ODINCKMPIJJUCX-UHFFFAOYSA-N calcium oxide Inorganic materials [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 description 1
- 230000003185 calcium uptake Effects 0.000 description 1
- MWKXCSMICWVRGW-UHFFFAOYSA-N calcium;phosphane Chemical compound P.[Ca] MWKXCSMICWVRGW-UHFFFAOYSA-N 0.000 description 1
- BHQCQFFYRZLCQQ-OELDTZBJSA-N cholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 BHQCQFFYRZLCQQ-OELDTZBJSA-N 0.000 description 1
- 229960002471 cholic acid Drugs 0.000 description 1
- 235000019416 cholic acid Nutrition 0.000 description 1
- 230000002301 combined effect Effects 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- KXGVEGMKQFWNSR-UHFFFAOYSA-N deoxycholic acid Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)C(O)C2 KXGVEGMKQFWNSR-UHFFFAOYSA-N 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000012447 hatching Effects 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 102000018358 immunoglobulin Human genes 0.000 description 1
- 229940072221 immunoglobulins Drugs 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000006651 lactation Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- FFEARJCKVFRZRR-UHFFFAOYSA-N methionine Chemical compound CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 description 1
- -1 methionine hydroxy analog calcium salt Chemical class 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
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- 238000011160 research Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
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- 230000036299 sexual function Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
Landscapes
- Fodder In General (AREA)
Abstract
The invention belongs to technical field of poultry farming, it is related to a kind of hydroxyl Methionine calcium salt and 25 hydroxy-vitamine Ds3Chicken feed, mixed fodder and application.Specifically, providing a kind of methionine hydroxy calcium and 25 hydroxy-vitamine Ds3Application in the feed for improving chicken body skeleton development is prepared；And methionine hydroxy calcium and 25 hydroxy-vitamine Ds3Application in the feed for improving chicken body weight gains is prepared；And methionine hydroxy calcium and 25 hydroxy-vitamine Ds3Application in the feed for improving egg quality is prepared, and contain methionine hydroxy calcium and 25 hydroxy-vitamine Ds3Chicken feed and mixed fodder.The effect that is improved to broiler chicken and laying hen quality of the invention.
Description
Technical field
The invention belongs to technical field of poultry farming, it is related to a kind of hydroxyl Methionine calcium salt and 25-hydroxy-vitamin D3's
Chicken feed, mixed fodder and application.
Background technology
Methionine hydroxy calcium is amino acid chelated calcium, and good water solubility is chemical entitled typically by methionine hydroxy analog
In DL-2- hydroxy-4-methylthiobutyric acids and calcium hydroxide or calcium oxide and obtain.MHA-Ca because of its special structural property, no
Only possess the nutrition immune function of methionine, promote calcium uptake, moreover it is possible to part is provided and is more easy to absorb calcium content, and can be in enteron aisle
Directly absorbed by amino acid special modality, infiltration rate is especially fast.
25-hydroxy-vitamin D3It is a kind of vitamin D metabolites, and is main vitamin D3Active metabolite.There is research
Show enteron aisle to 25-OH-D3Absorption be better than to vitamin D3Absorption, because it is not influenceed by cholic acid and fat absorption are bad.
Soares etc. (1995) reports, 25-OH-D3Biological value be vitamin D31-4 times, and 25-OH-D3With the absorption of calcium
Between generally there are positive correlation (Heaney etc., 1997；Reamer etc., 1990；Bell etc., 1988；Francis etc., 1983).
Thus calcium, effective absorption and utilization of phosphorus are promoted, shin bone ash content, bone strength to poultry, calcium level have improvement result.
Chinese patent literature discloses a kind of 25- hydroxy-vitamins D3Purposes [application for improving animal life power
Number：200680051835.3], it is related to 25- hydroxy-vitamins D3For improving at least in the gestational period and/or the female of nursing period
The purposes of the general health status of animal.Further relate to 25- hydroxy-vitamins D3Purposes in animal reproduction.More specifically,
It is related to 25- hydroxy-vitamins D3For improve the litter size in pig reproductive process and porkling vitality purposes and
Subtract for providing the preferable physique of sow and gilt, improving gestation backfat gain, reduction lactation backfat loss
Purposes that is a small amount of and increasing nursing period Feed consumption.Above-mentioned file is not instructed or implied：Use methionine hydroxy calcium and 25- hydroxyls
The combination of base vitamine D3 can be to the feed intake of poultry broiler chicken, skeleton development, body weight gains and the unexpected effect of Egg Quality.
The content of the invention
Regarding the issue above, the present invention provides a kind of methionine hydroxy calcium and 25-hydroxy-vitamin D3In system
Application in the standby feed for improving chicken body skeleton development.
It is a further object of the present invention to provide a kind of methionine hydroxy calcium and 25-hydroxy-vitamin D3Improve chicken body preparing
Application in the feed of weightening.
Another object of the present invention is to provide a kind of methionine hydroxy calcium and 25-hydroxy-vitamin D3Improve egg preparing
Application in the feed of quality.
Another object of the present invention is to provide a kind of containing methionine hydroxy calcium and 25-hydroxy-vitamin D3Chicken feed.
Another object of the present invention is to provide a kind of containing methionine hydroxy calcium and 25-hydroxy-vitamin D3Mixing raise
Material.
To reach above-mentioned purpose, present invention employs following technical proposal：Methionine hydroxy calcium and 25-hydroxy-vitamin D3
Application in the feed for improving chicken body skeleton development is prepared.
Methionine hydroxy calcium and 25-hydroxy-vitamin D3Application in the feed for improving chicken body weight gains is prepared.
Methionine hydroxy calcium and 25-hydroxy-vitamin D3Application in the feed for improving egg quality is prepared.
One kind contains methionine hydroxy calcium and 25-hydroxy-vitamin D3Chicken feed, described methionine hydroxy calcium is in chicken
Content in feed is 6-42g/kg, described 25-hydroxy-vitamin D3Content in chicken feed is 600-1380ug/kg.
Above-mentioned containing methionine hydroxy calcium and 25-hydroxy-vitamin D3Chicken feed in, described hydroxy methionine
Content of the calcium in chicken feed is 42g/kg, described 25-hydroxy-vitamin D3Content in chicken feed is 1380ug/kg.
Above-mentioned containing methionine hydroxy calcium and 25-hydroxy-vitamin D3Chicken feed in, also include in this chicken feed
Following components：Vitamin A 11000IU/kg, vitamin E 22mg/kg, vitamin K32.0mg/kg, vitamin B1 1.6mg/
Kg, vitamin B26.1mg/kg, vitamin B63.7mg/kg, vitamin B1217mg/kg, pantothenic acid 10.8mg/kg, niacinamide
36.0mg/kg, folic acid 1.0mg/kg, biotin 110mg/kg, Choline Chloride 350mg/kg, copper 5.4mg/kg, iron 75mg/kg,
Zinc 75mg/kg, manganese 110mg/kg, selenium 245mg/kg, iodine 680mg/kg, calcium 9g/kg, available phosphorus 2.1g/kg.
Above-mentioned containing methionine hydroxy calcium and 25-hydroxy-vitamin D3Chicken feed in, described chicken feed is boiling
Stone flour and/or system chaff are used as carrier.
A kind of mixed fodder, above-mentioned any one feed is delivered with weight than 5% and is mixed in daily grain of chicken, forms mixing
Feed.
In above-mentioned mixed fodder, the component containing following mass fraction in described daily grain of chicken：Corn 61.5-65
Part, wheat bran 0-10 parts, dregs of beans 23-28 parts, soybean oil 0-3 parts, stone flour 0-7.5 parts.
In above-mentioned mixed fodder, in 7-21 age in days broiler diets, described daily grain of chicken contains following mass parts
Several components：62 parts of corn, 2 parts of wheat bran, 28 parts of dregs of beans, 2 parts of soybean oil, 1 part of stone flour；
In 22-42 age in days broiler diets, described daily grain of chicken contains the component of following mass fraction：64 parts of corn,
2 parts of wheat bran, 25 parts of dregs of beans, 2 parts of soybean oil, 1 part of stone flour；
In the layer dietses for opening product the last fortnight-open product, described daily grain of chicken contains the component of following mass fraction：Corn
62 parts, 10 parts of wheat bran, 23 parts of dregs of beans；
In the layer dietses for opening product-laying rate 5%, described daily grain of chicken contains the component of following mass fraction：Corn
65 parts, 1 part of wheat bran, 25 parts of dregs of beans, 0.5 part of soybean oil, 3.5 parts of stone flour；
In the layer dietses of laying rate 5%- laying rate 60%, described daily grain of chicken contains the group of following mass fraction
Point：61.5 parts of corn, 24.5 parts of dregs of beans, 2 parts of soybean oil, 7 parts of stone flour；
In the layer dietses that laying rate 60%- terminates, described daily grain of chicken contains the component of following mass fraction：Corn
62 parts, 24 parts of dregs of beans, 1.5 parts of soybean oil, 7.5 parts of stone flour.
Compared with prior art, the advantage of the invention is that：
Methionine hydroxy calcium is methionine hydroxy analog calcium salt, is easy to be absorbed in enteron aisle, in animal body can picture
Methionine equally participates in the synthesis of protein and sulfur-bearing active material, and participates in methyl metabolism process.Limited as poultry first
The analog of acidic amino acid, instead of DL- METHIONINE using can also play oxidation resistance, and improves Fresh Grade Breast and carcass weight.
25-hydroxy-vitamin D of the invention3As vitamin D3The first active metabolite, its active potency better than dimension give birth to
Plain D3, except playing vitamin D3Nutrition sexual function, also promote calcium, phosphorus balance limited absorbent, participate in immunological regulation and growth promotion
Mechanism.And can be used for poult by the incoming hatching egg of parent.
Methionine hydroxy calcium and 25-hydroxy-vitamin D3Be applied in combination and can further adjust body Ca,P metabolism, promote
Skeleton development, its function is better than individually addition methionine hydroxy calcium and 25-hydroxy-vitamin D3Effect, similarly for Egg Quality
There is more excellent effect.
For laying hen, during 25-hydroxyvitamin D3 can be by the incoming egg of parent, but vitamine D3 cannot, also promote
Enter 25-hydroxyvitamin D3 to reduce rate of broken eggs, improve eggshell quality, improve the function of hatchable egg rate.
Specific embodiment
Reagent used in following embodiments, unless otherwise specified, can be commercially available from routine biochemistry reagent shop.With
Quantitative data in lower embodiment, is respectively provided with three repetitions and tests, results averaged.
Embodiment 1
One kind contains methionine hydroxy calcium and 25-hydroxy-vitamin D3Chicken feed, by 6g methionine hydroxy calciums,
0.6mg25- hydroxy-vitamine Ds3It is well mixed with 999.4g system chaffs, obtains hydroxy methionine calcium content for 6g/kg, 25- hydroxyls
Vitamin D3Content is the chicken feed of 600ug/kg.
Embodiment 2
One kind contains methionine hydroxy calcium and 25-hydroxy-vitamin D3Chicken feed, by 42g methionine hydroxy calciums,
1.38mg25- hydroxy-vitamine Ds3It is well mixed with 995.8g zeolite powders, hydroxy methionine calcium content is obtained for 42g/kg, 25-
Hydroxy-vitamine D3Content is the chicken feed of 1380ug/kg.
Embodiment 3
One kind contains methionine hydroxy calcium and 25-hydroxy-vitamin D3Chicken feed, by 42g methionine hydroxy calciums,
0.6mg25- hydroxy-vitamine Ds3, 500g zeolite powders and 495.8g system chaff be well mixed, obtaining hydroxy methionine calcium content is
42g/kg, 25-hydroxy-vitamin D3Content is the chicken feed of 600ug/kg.
Embodiment 4
One kind contains methionine hydroxy calcium and 25-hydroxy-vitamin D3Chicken feed, by 6g methionine hydroxy calciums,
1.38mg25- hydroxy-vitamine Ds3It is well mixed with 998.4g zeolite powders, hydroxy methionine calcium content is obtained for 6g/kg, 25- hydroxyls
Base vitamin D3Content is the chicken feed of 1380ug/kg.
Embodiment 5
One kind contains methionine hydroxy calcium and 25-hydroxy-vitamin D3Chicken feed, by 6g methionine hydroxy calciums,
1.1mg25- hydroxy-vitamine Ds3, 115.8g system chaffs and 883.4g zeolite powders it is well mixed, obtaining hydroxy methionine calcium content is
6g/kg, 25-hydroxy-vitamin D3Content is the chicken feed of 1100ug/kg.
Embodiment 6
The present embodiment can be in optional embodiment 1-5 methionine hydroxy calcium and 25-hydroxy-vitamin D3Combination, and add
Various vitamins, trace element, conventional mineral matter, salt, amino acid, enzyme preparation and carrier, carrier selection zeolite powder and/or system
Chaff, so that hydroxy methionine calcium content is formed for 6-42g/kg, 25-hydroxy-vitamin D3Content is 600-1380ug/kg, dimension life
Plain A 11000IU/kg, vitamin E 22mg/kg, vitamin K32.0mg/kg, vitamin B11.6mg/kg, vitamin B2
6.1mg/kg, vitamin B63.7mg/kg, vitamin B1217mg/kg, pantothenic acid 10.8mg/kg, niacinamide 36.0mg/kg, leaf
Sour 1.0mg/kg, biotin 110mg/kg, Choline Chloride 350mg/kg, copper 5.4mg/kg, iron 75mg/kg, zinc 75mg/kg, manganese
110mg/kg, selenium 245mg/kg, iodine 680mg/kg, calcium 9g/kg, the chicken feed of available phosphorus 2.1g/kg.
Embodiment 7
A kind of mixed fodder, including the embodiment 1-6 of 5%wt chicken feed, and 95wt% daily grain of chicken.
It will be appreciated by those skilled in the art that daily grain of chicken can be the food of various suitable chicken feed.
In the present embodiment, as preferred scheme, daily grain of chicken includes the group of corn, wheat bran, dregs of beans, soybean oil and stone flour
Close.
Embodiment 8
A kind of mixed fodder, including 5kg embodiments 1-6 any one chicken feed, and basal diet 95kg, basal diet
Including corn 61.5-65kg, wheat bran 0-10kg, dregs of beans 23-28kg, soybean oil 0-3kg, stone flour 0-7.5kg, mixed fodder gross weight
100kg。
Embodiment 9
A kind of mixed fodder, including 5kg embodiments 1-6 any one chicken feed, and basal diet 95kg, basal diet
Including corn 62kg, wheat bran 2kg, dregs of beans 28kg, soybean oil 2kg, stone flour 1kg, mixed fodder gross weight 100kg.
Embodiment 10
A kind of mixed fodder, it is adaptable to 7-21 age in days Broiler chicks, including 5kg embodiments 1-6 any one chicken feed, and
Basal diet 95kg, basal diet includes corn 62kg, wheat bran 2kg, dregs of beans 28kg, soybean oil 2kg, stone flour 1kg, mixed fodder
Gross weight 100kg.
Embodiment 11
A kind of mixed fodder, it is adaptable to 22-42 age in days Broiler chicks, including 5kg embodiments 1-6 any one chicken feed, with
And basal diet 95kg, basal diet include corn 64kg, wheat bran 2kg, dregs of beans 25kg, soybean oil 2kg, stone flour 1kg.
Embodiment 12
A kind of mixed fodder, it is adaptable to open the laying hen of product the last fortnight-open product, including any one breeders of 5kg embodiments 1-6 are raised
Material, and basal diet 95kg, basal diet include corn 62kg, wheat bran 10kg, dregs of beans 23kg, mixed fodder gross weight 100kg.
Embodiment 13
A kind of mixed fodder, it is adaptable to open the laying hen of product-laying rate 5%, including any one breeders of 5kg embodiments 1-6 are raised
Material, and basal diet 95kg, basal diet include corn 65kg, wheat bran 1kg, dregs of beans 25kg, soybean oil 0.5kg, stone flour
3.5kg, mixed fodder gross weight 100kg.
Embodiment 14
A kind of mixed fodder, it is adaptable to which the laying hen of laying rate 5%- laying rate 60%, including 5kg embodiments 1-6 is any one
Breeding hen feed, and basal diet 95kg, basal diet include corn 61.5kg, dregs of beans 24.5kg, soybean oil 2kg, stone flour
7kg, mixed fodder gross weight 100kg.
Embodiment 15
A kind of mixed fodder, it is adaptable to the laying hen that laying rate 60%- terminates, including any one breeders of 5kg embodiments 1-6 are raised
Material, and basal diet 95kg, basal diet include corn 62kg, dregs of beans 24kg, soybean oil 1.5kg, stone flour 7.5kg, mixing
Feed gross weight 100kg.
Application examples 1
7-42 ages in days broiler is selected for subjects, from the chicken feed 5kg and embodiment 10 or 11 of embodiment 2
Basal diet 95kg is mixed to form mixed fodder.
Subjects are divided into 4 groups, and A groups are control groups with containing methionine and vitamin D3Replace the hydroxyl egg in mixed fodder
Propylhomoserin calcium and 25-hydroxy-vitamin D3, B groups are the methionine hydroxy calciums during methionine replaces mixed fodder, and C groups are vitamin Ds3
Replace the 25-hydroxy-vitamin D in mixed fodder3, D groups feed with above-mentioned mixed fodder.
As shown in Table 1, A groups will be less than other groups in per day feed intake, average daily gain, and feed-weight ratio is higher than remaining
Group.Two groups of B, C gaps in production performance index are little.And the per day feed intake and average daily gain expression effect of D groups are most
Good, better than remaining each group, feed-weight ratio is minimum.Illustrate that this product can improve the efficiency of feed utilization of Broiler chicks, improve its production performance,
Combined effect is more preferable.
Influence of this product of table 1 to 7-42 age in days broiler growth performances
Application examples 2
7-42 ages in days broiler is selected for subjects, from the chicken feed 5kg and embodiment 10 or 11 of embodiment 2
Basal diet 95kg is mixed to form mixed fodder.
Subjects are divided into 4 groups, and A groups are control groups with containing methionine and vitamin D3Replace the hydroxyl egg in mixed fodder
Propylhomoserin calcium and 25-hydroxy-vitamin D3, B groups are the methionine hydroxy calciums during methionine replaces mixed fodder, and C groups are vitamin Ds3
Replace the 25-hydroxy-vitamin D in mixed fodder3, D groups feed with above-mentioned mixed fodder.
As shown in Table 2, A groups are below other groups on tibia length, the dry weight of shin bone half and shin bone calcium content.B group shin bones
Phosphorus content is slightly below A groups, illustrates that methionine hydroxy calcium can not improve the utilization rate of phosphorus.C groups are with B groups in tibia length, shin bone
It is very nearly the same in half dry weight and shin bone calcium.And D groups are in addition to shin bone ash weight/half dry weight index, remaining index is superior to other groups,
Illustrate 25-OH-D3There are reciprocal effects with methionine hydroxy calcium.
Understand, the chicken feed of embodiment 2 can promote Broiler chicks calcium, phosphorus to absorb, and promote bone development, improve the calcium phosphorus of shin bone
Deposition, reduces the rickety risk of Broiler chicks.
Influence of this product of table 2 to 7-42 age in days broiler Tibia Developments
Application examples 3
7-42 ages in days broiler is selected for subjects, from the chicken feed 5kg and embodiment 10 or 11 of embodiment 2
Basal diet 95kg is mixed to form mixed fodder.
Subjects are divided into 4 groups, and A groups are control groups with containing methionine and vitamin D3Replace the hydroxyl egg in mixed fodder
Propylhomoserin calcium and 25-hydroxy-vitamin D3, B groups are the methionine hydroxy calciums during methionine replaces mixed fodder, and C groups are vitamin Ds3
Replace the 25-hydroxy-vitamin D in mixed fodder3, D groups feed with above-mentioned mixed fodder.
As shown in table 3,25-OH-D3Or after methionine hydroxy calcium is substituted, different immunoglobulins have different width in serum
The raising of degree, illustrates that its immunity just constantly strengthens.It is former but the content of Phos has no significant difference between each group in serum
The preliminary stage of animal is acted on because of the active component for being this product, the animal later stage has possessed the ability of self regulating and control.Serum calcium
Content and Tibia Development index (example 2) being consistent property.
Influence of this product of table 3 to 7-42 age in days broiler sero-immunity indexs
Application examples 4
7-42 ages in days broiler is selected for subjects, from the chicken feed 5kg and embodiment 10 or 11 of embodiment 2
Basal diet 95kg is mixed to form mixed fodder.
Subjects are divided into 4 groups, and A groups are control groups with containing methionine and vitamin D3Replace the hydroxyl egg in mixed fodder
Propylhomoserin calcium and 25-hydroxy-vitamin D3, B groups are the methionine hydroxy calciums during methionine replaces mixed fodder, and C groups are vitamin Ds3
Replace the 25-hydroxy-vitamin D in mixed fodder3, D groups feed with above-mentioned mixed fodder.
Shown in the result of table 4,25-OH-D3Or after methionine hydroxy calcium is substituted, improve superoxide dismutase in serum
The content of SOD, glutathione peroxidase DSH-Px, reductive glutathione GSH and TAC T-AOC, and drop
The low content of MDA MDA, illustrates that this product can improve the oxidation resistance of body.
Influence of this product of table 4 to 7-42 age in days broiler Serum antioxidant indices
Application examples 5
18 week old commodity eggs are subjects, from the chicken feed 5kg and embodiment 13,14 or 15 of embodiment 1
Basal diet 95kg is mixed to form mixed fodder.Subjects are divided into 4 groups, and A groups are control groups with containing methionine and vitamin D3
Replace the methionine hydroxy calcium and 25-hydroxy-vitamin D in mixed fodder3, B groups are the hydroxyls during methionine replaces mixed fodder
Methionine calcium salt, C groups are vitamin Ds3The 25-hydroxyvitamin D3 in mixed fodder is replaced, D groups are fed with above-mentioned mixed fodder.
Experimental period is 2 weeks, the end off-test of 20 week old.
Such as table 5, compared with A groups, 25-OH-D3Or methionine hydroxy calcium substitute after can improve laying rate, average egg weight and
Feed intake so that chicken group enters first term (laying rate up to 5%) as early as possible.Each production performance of D groups is superior to other groups, shows this product
Product can be used on laying hen, and improve Chicken in Initial Laying Period production performance.Meanwhile, laying hen body weight gradually increases, and egg does not occur
The excessively fat phenomenon of chicken body weight.
Influence of this product of table 5 to the first term production performance of 18-20 week old commodity egg
Application examples 6
21 week old commodity eggs are selected for subjects, from the chicken feed 5kg and embodiment 13,14 or 15 of embodiment 2
Basal diet 95kg be mixed to form mixed fodder.Subjects are divided into 4 groups, and A groups are control groups with containing methionine and vitamin
D3Replace the methionine hydroxy calcium and 25-hydroxy-vitamin D in mixed fodder3, B groups are the hydroxyls during methionine replaces mixed fodder
Base Methionine calcium salt, C groups are vitamin Ds3Replace the 25-hydroxy-vitamin D in mixed fodder3, D groups feed with above-mentioned mixed fodder.
Experimental period is 7 weeks, during off-test, per 2 pieces of eggs of repeated collection, determines Egg Quality.
During such as table 6 and the week old of table 7,27 end, only A groups are not up to peak of laying eggs (laying rate is more than 80%), remaining each group
Egg-laying peak is reached.25-OH-D3Or can improve average egg weight and feed intake after methionine hydroxy calcium replacement so that chicken
Group reaches peak of laying eggs as early as possible.Meanwhile, laying hen weight gain is normal, the excessively fat phenomenon of laying hen body weight does not occur.
Influence of this product of table 6 to 21-27 week old commodity egg production performances
Influence of this product of table 7 to 21-27 week old commodity egg Egg Qualities
25-OH-D3Or after hydroxyl egg ammonia calcium is substituted, the egg shape index of egg has no bigger difference, concentrates on 1.28-1.30
(being shown in Table 7)；Hangh unit is the important indicator for weighing Chicken Albumin quality, and hangh unit more high protein is more sticky, albumen product
Matter is better.According to grade grade scale, hangh unit ＞ 72 is AA grades, and 72 ＞ hangh units ＞ 60 are A grades, and hangh unit ＜ 60 is
B grades.In this experiment, hangh unit reaches AA grades (hangh unit ＞ 72), illustrates this product to egg quality and has no adverse effects.
Compared with C groups, the shell thickness of B groups is thicker, illustrates that hydroxy methionine can improve shell thickness.The eggshell of D groups is thick
Degree is maximum with eggshell ratio increase rate, and effect is best.
25-OH-D3Or after hydroxyl egg ammonia calcium is substituted, shell thickness can be increased, and the ratio of eggshell is improved, improve eggshell matter
Amount, reduces rate of broken eggs, so as to increase the qualification rate of commodity egg.
Application examples 7
28 week old commodity eggs are selected for subjects, from the chicken feed 5kg and embodiment 13,14 or 15 of embodiment 3
Basal diet 95kg be mixed to form mixed fodder.
Subjects are divided into 4 groups, and A groups are control groups with containing methionine and vitamin D3Replace the hydroxyl egg in mixed fodder
Propylhomoserin calcium and 25-hydroxy-vitamin D3, B groups are the methionine hydroxy calciums during methionine replaces mixed fodder, and C groups are vitamin Ds3
Replace the 25-hydroxy-vitamin D in mixed fodder3, D groups feed with above-mentioned mixed fodder.Experimental period was 6 weeks, at the 34th week
Sampling.
Such as table 8,25-OH-D3Or laying rate, average egg weight and feed intake can be improved after methionine hydroxy calcium replacement, drop
Low feedstuff-egg ratio.C groups are high compared with B groups laying rate, but average egg weight is but lower than B groups with feed intake.Each production performance of D groups is superior to
Other groups, show that this product can be used on laying hen, and can improve the production performance of laying hen.
Influence of this product of table 8 to 28-34 week old commodity egg production performances
25-OH-D3Or after hydroxyl egg ammonia calcium is substituted, the egg shape index of egg has no very big difference；According to hangh unit
In measurement index, this experiment, hangh unit reaches AA grades (hangh unit ＞ 72), and this product has no bad shadow to egg quality
Ring.
Compared with C groups, the shell thickness of B groups is thicker, illustrates that hydroxy methionine can improve shell thickness.The eggshell of D groups is thick
Degree is maximum with eggshell ratio increase rate, and effect is best.
25-OH-D3Or after hydroxyl egg ammonia calcium is substituted, shell thickness can be increased, and the ratio of eggshell is improved, improve eggshell matter
Amount, reduces rate of broken eggs, so as to increase the qualification rate of commodity egg.
Influence of this product of table 9 to 28-34 week old commodity egg Egg Qualities
Specific embodiment described herein is only to the spiritual explanation for example of the present invention.Technology neck belonging to of the invention
The technical staff in domain can be made various modifications or supplement to described specific embodiment or be replaced using similar mode
Generation, but without departing from spirit of the invention or surmount scope defined in appended claims.
Claims (10)
1. methionine hydroxy calcium and 25-hydroxy-vitamin D3Application in the feed for improving chicken body skeleton development is prepared.
2. methionine hydroxy calcium and 25-hydroxy-vitamin D3Application in the feed for improving chicken body weight gains is prepared.
3. methionine hydroxy calcium and 25-hydroxy-vitamin D3Application in the feed for improving egg quality is prepared.
4. it is a kind of to contain methionine hydroxy calcium and 25-hydroxy-vitamin D3Chicken feed, it is characterised in that described hydroxyl egg ammonia
Content of the sour calcium in chicken feed is 6-42g/kg, described 25-hydroxy-vitamin D3Content in chicken feed is 600-
1380ug/kg。
5. according to claim 4 containing methionine hydroxy calcium and 25-hydroxy-vitamin D3Chicken feed, it is characterised in that
Content of the described methionine hydroxy calcium in chicken feed is 42g/kg, described 25-hydroxy-vitamin D3In chicken feed
Content is 1380ug/kg.
6. according to claim 5 containing methionine hydroxy calcium and 25-hydroxy-vitamin D3Chicken feed, it is characterised in that
Also include following components in this chicken feed：Vitamin A 11000IU/kg, vitamin E 22mg/kg, vitamin K3 2.0mg/
Kg, vitamin B11.6mg/kg, vitamin B26.1mg/kg, vitamin B63.7mg/kg, vitamin B1217mg/kg, pantothenic acid
10.8mg/kg, niacinamide 36.0mg/kg, folic acid 1.0mg/kg, biotin 110mg/kg, Choline Chloride 350mg/kg, copper
5.4mg/kg, iron 75mg/kg, zinc 75mg/kg, manganese 110mg/kg, selenium 245mg/kg, iodine 680mg/kg, calcium 9g/kg, available phosphorus
2.1g/kg。
7. methionine hydroxy calcium and 25-hydroxy-vitamin D are contained according to claim 4-6 any one3Chicken feed,
Characterized in that, described chicken feed is using zeolite powder and/or system chaff as carrier.
8. a kind of mixed fodder, it is characterised in that throw the chicken feed described in claim 4-7 any one than 5% with weight
Mixing in daily grain of chicken is put into, mixed fodder is formed.
9. mixed fodder according to claim 8, it is characterised in that containing following mass fraction in described daily grain of chicken
Component：Corn 61.5-65 parts, wheat bran 0-10 parts, dregs of beans 23-28 parts, soybean oil 0-3 parts, stone flour 0-7.5 parts.
10. mixed fodder according to claim 9, it is characterised in that in 7-21 age in days broiler diets, described chicken
Daily ration contains the component of following mass fraction：62 parts of corn, 2 parts of wheat bran, 28 parts of dregs of beans, 2 parts of soybean oil, 1 part of stone flour；
In 22-42 age in days broiler diets, described daily grain of chicken contains the component of following mass fraction：64 parts of corn, wheat bran 2
Part, 25 parts of dregs of beans, 2 parts of soybean oil, 1 part of stone flour；
In the layer dietses for opening product the last fortnight-open product, described daily grain of chicken contains the component of following mass fraction：Corn 62
Part, 10 parts of wheat bran, 23 parts of dregs of beans；
In the layer dietses for opening product-laying rate 5%, described daily grain of chicken contains the component of following mass fraction：65 parts of corn,
1 part of wheat bran, 25 parts of dregs of beans, 0.5 part of soybean oil, 3.5 parts of stone flour；
In the layer dietses of laying rate 5%- laying rate 60%, described daily grain of chicken contains the component of following mass fraction：It is beautiful
61.5 parts of rice, 24.5 parts of dregs of beans, 2 parts of soybean oil, 7 parts of stone flour；
In the layer dietses that laying rate 60%- terminates, described daily grain of chicken contains the component of following mass fraction：Corn 62
Part, 24 parts of dregs of beans, 1.5 parts of soybean oil, 7.5 parts of stone flour.
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| CN109123181A (en) * | 2018-08-14 | 2019-01-04 | 播恩生物技术股份有限公司 | Improve laying hen bone density and the premixed feed of eggshell quality and preparation method thereof |
| CN109805208A (en) * | 2019-04-04 | 2019-05-28 | 张金春 | A kind of chicken feed and preparation method thereof of midwifery high nutritive value egg |
| CN112655836A (en) * | 2020-12-18 | 2021-04-16 | 广西北海市旺海生物科技有限公司 | Compound feed beneficial to improving bone strength of broiler chicken |
| CN113598284A (en) * | 2021-08-16 | 2021-11-05 | 广东省农业科学院动物科学研究所 | Application of 25-OH-VD3 in improving ovarian development and egg-laying performance |
| CN113749195A (en) * | 2021-10-20 | 2021-12-07 | 山东畜牧兽医职业学院 | A kind of VD3-rich chicken feed and production method of VD3-rich eggs |
| CN114521535A (en) * | 2022-03-22 | 2022-05-24 | 四川农业大学 | Feeding method for improving bone quality of laying hens |
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| CN109805208A (en) * | 2019-04-04 | 2019-05-28 | 张金春 | A kind of chicken feed and preparation method thereof of midwifery high nutritive value egg |
| CN112655836A (en) * | 2020-12-18 | 2021-04-16 | 广西北海市旺海生物科技有限公司 | Compound feed beneficial to improving bone strength of broiler chicken |
| CN113598284A (en) * | 2021-08-16 | 2021-11-05 | 广东省农业科学院动物科学研究所 | Application of 25-OH-VD3 in improving ovarian development and egg-laying performance |
| CN113749195A (en) * | 2021-10-20 | 2021-12-07 | 山东畜牧兽医职业学院 | A kind of VD3-rich chicken feed and production method of VD3-rich eggs |
| CN114521535A (en) * | 2022-03-22 | 2022-05-24 | 四川农业大学 | Feeding method for improving bone quality of laying hens |
| CN116349796A (en) * | 2023-04-11 | 2023-06-30 | 湖南金汇龙科技有限公司 | Feed for improving skeletal development of chickens and preparation and application thereof |
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