CN106606744A - Combination medicament for treating type 2 diabetes mellitus - Google Patents

Abstract

The invention discloses a combined medicine for treating type Ⅱ diabetes, which is composed of astragalus, ginseng, privet fruit, medlar, Jiaobaizhu, rehmannia glutinosa, kudzu root, curcuma, gallinacea, purslane, dandelion, wood It is made of 16 kinds of herbal medicines such as incense, lichen, white radish, sweet potato leaf, willow leaf and acacia leaf. It has the curative effect of quick effect, short course of treatment, high cure rate and low recurrence rate.

Description

Combination medicine for treating type 2 diabetes

technical field

The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a combination medicine for treating type II diabetes.

Background technique

Diabetes (known as diabetes in Chinese medicine) is a relatively common disease in society at present, and with the improvement of living standards, the incidence of diabetes is getting higher and higher. Western medicine believes that diabetes is a syndrome of sugar, protein, and fat metabolism disorders caused by the lack of insulin in the body or the inability of insulin to play a normal physiological role in target cells. The basic feature of diabetes is long-term high blood sugar, which can damage multiple systems of the body, mainly the cardiovascular system. Prolonged illness can also lead to chronic progressive lesions in the eyes, kidneys, nerves, heart, blood vessels and other tissues, causing functional defects and failure. The symptoms of diabetes can be divided into two categories: a large category is related to metabolic disorders, especially "three more and one less" related to hyperglycemia, which is more common in type 1 diabetes; type 2 diabetes is often not very obvious or only There are partial performances. The main reason for the increase in blood sugar in type 2 diabetes is that the sugar absorbed by the gastrointestinal tract cannot be sent to peripheral parts such as limbs and skin in time. high.

The traditional theory believes that the cause of diabetes is related to the following three factors: 1. Genetic factors. Diabetes is a hereditary disease. Genetic studies have shown that the incidence of diabetes is significantly different between blood relatives and non-blood relatives, and the former is higher than the latter. Out about 5 times. The importance of genetic factors in the etiology of type 1 diabetes is about 50%, while the importance of genetic factors in the etiology of type 2 diabetes is more than 90%; 2. Mental factors have been confirmed by Chinese and foreign scholars in recent times The role of mental factors in the occurrence and development of diabetes is believed to be accompanied by mental tension, emotional agitation and various stress states, which will cause a large amount of secretion of blood sugar-raising hormones, such as growth hormone, norepinephrine, and glucagon. 3. Obesity factors. At present, it is believed that obesity is an important inducing factor of diabetes. 60%-80% of adult diabetic patients are obese before the onset of diabetes. The degree of obesity is positively related to the incidence of diabetes. And with the increase of age, when physical activity gradually decreases, the ratio of human muscle to fat is also changing. From 25 to 75 years old, muscle tissue gradually decreases from 47% to 36% of body weight, while fat Increased from 20% to 36%, which is one of the main reasons for the obvious increase of diabetes in the elderly, especially the obese and fat elderly; Diabetes is induced by overburdening the potentially hypofunctioning insulin β-cells. At present, the concept of "the richer the life, the fuller the body, the more diabetes will increase" has been formed at home and abroad.

At present, the treatment of diabetes at home and abroad is divided into two types: traditional Chinese medicine and western medicine. Western medicine mainly relies on insulin, which takes a long time to take and has many side effects, and microvascular lesions may occur; biguanide drugs have low curative effect and large side effects. Chinese medicine has a long history of treating diabetes in my country. In recent times, more and more traditional Chinese medicine prescriptions have been released to the world. However, looking at these technologies, most of them are aimed at solving the deficiency of both yin and yang in diabetes, supplemented by drugs for promoting blood circulation and removing blood stasis. , the therapeutic effect is not satisfactory. Such as the Chinese medicine for treating diabetes disclosed in CN101700354B patent, its formula is: 1-5 parts of American ginseng, 2-6 parts of Anemarrhena, 1-5 parts of gypsum, 3-8 parts of balsam pear, 2-6 parts of silkworm cocoons, 1-5 parts of astragalus, 1-5 parts of Chinese yam, 1-5 parts of raw land, 1-5 parts of Scrophulariaceae, 1-5 parts of Adenophora, 1-5 parts of Ophiopogon japonicus, 1-5 parts of Polygonatum Polygonatum, 1-5 parts of Polygonatum, 1-5 parts of Trichosanthum Fen 5 parts, 1-5 parts of gallinacea, 1-5 parts of coptis, 1-5 parts of cornus, 2-7 parts of medlar, 2-7 parts of privet fruit, 1-5 parts of epimedium; CN103751344A discloses A medicine for treating diabetes, which is composed of active ingredients and/or chemically acceptable carriers, and the active ingredients are made of 5-15 parts of aconite, 1-5 parts of cinnamon, 5-15 parts of Morinda officinalis, etc.

Contents of the invention

Aiming at the defects of the prior art, the invention provides a combination medicine for treating type Ⅱ diabetes, which can effectively treat type Ⅱ diabetes, has high cure rate and low recurrence rate.

The technical solution adopted to achieve the above object is: a combined medicine for treating type II diabetes, which is made of the following medicines in parts by weight: 15-20 parts of astragalus, 15-20 parts of ginseng, 10-15 parts of Ligustrum lucidum , 15-25 parts of medlar, 10-15 parts of Jiaobaizhu, 15-20 parts of Rehmannia glutinosa, 15-20 parts of kudzu root, 8-10 parts of turmeric, 10-15 parts of gallinaceous gold, 8-10 parts of purslane, 8-10 parts of dandelion, 5-8 parts of woody fragrance, 20-30 parts of lichen, 20-30 parts of white radish leaves, 20-30 parts of sweet potato leaves, 15-20 parts of willow leaves, 15-20 parts of acacia leaves.

The combined medicine for treating type Ⅱ diabetes is made of the following medicines in parts by weight:

15 parts of astragalus, 15 parts of ginseng, 10 parts of Ligustrum lucidum, 20 parts of medlar, 10 parts of Jiaobaizhu, 15 parts of Rehmannia glutinosa, 15 parts of kudzu root, 10 parts of turmeric, 15 parts of gallinaceous gold, 10 parts of purslane, dandelion 10 parts, 5 parts of woody fragrance, 30 parts of lichen, 30 parts of white radish leaves, 30 parts of sweet potato leaves, 20 parts of willow leaves, and 20 parts of acacia leaves. The scheme of this embodiment is suitable for patients with early type Ⅱ diabetes.

The combined medicine for treating type Ⅱ diabetes is made of the following medicines in parts by weight:

20 parts of astragalus, 20 parts of ginseng, 15 parts of Ligustrum lucidum, 25 parts of medlar, 10 parts of Jiaobaizhu, 20 parts of Rehmannia glutinosa, 20 parts of kudzu root, 8 parts of turmeric, 10 parts of gallinaceous gold, 8 parts of purslane, dandelion 8 parts, 8 parts of woody fragrance, 20 parts of lichen, 20 parts of white radish leaves, 20 parts of sweet potato leaves, 15 parts of willow leaves, and 15 parts of acacia leaves. The scheme of this embodiment is suitable for patients with type Ⅱ diabetes mellitus in the middle and late stages.

The white radish leaves and sweet potato leaves are picked before the Mid-Autumn Festival, and the willow leaves and acacia leaves are picked before the Qingming Festival.

The white radish leaves, sweet potato leaves, willow leaves and acacia leaves are dried at low temperature, and the drying temperature does not exceed 50°C.

The white radish leaves, sweet potato leaves, willow leaves and acacia leaves are vacuum-dried at room temperature.

The inventor combines traditional cognition, and through investigation and research on the lifestyle and structure of modern society, believes that with the affluence of life, the diet loses restraint, overnutrition, life is more static and less active, digestion and absorption functions are weakened, and people are under mental stress for a long time Liver and kidney are overwhelmed, various organs and blood system are stagnant and detoxified, and other living conditions are the main factors that induce diabetes. Over time, more and more stasis accumulates, the body becomes weaker and heavier, and the accumulated weight is difficult to return. Obesity and edema cause this syndrome. Therefore, the incidence of diabetes has become higher and higher in recent times, and the onset period has been advancing. Modern Western medicine seeks to control long-term medication, and its side effects are likely to cause other diseases. Patients live in fear, and their mental burden is getting heavier and heavier. Traditional Chinese medicine mostly treats deficiency syndromes, with Yin and Yang tonic as the first priority, or supplemented with medicines that cool blood, nourish blood, activate blood and remove blood stasis. New stasis. Therefore, the present invention starts with eliminating blood stasis and blood endotoxins in the body and internal organs, and also performs heat-clearing and detoxifying, cooling blood and nourishing blood, promoting blood circulation and removing blood stasis, soothing the liver and relieving stagnation, rectifying the source, and then nourishing yin and nourishing yang, consolidating the root and strengthening the body. At the end, in order to achieve the effect of treating both symptoms and root causes, endow patients with a strong body.

Main advantage of the present invention is:

The combined medicine for treating type Ⅱ diabetes of the present invention first breaks blood stasis and detoxifies, clears heat and relieves stagnation, removes blood stasis, and rectifies the root causes, so that glutinous rice can be taken in, blood can flow forward, sugar poison can be eliminated, and insulin cells can be regenerated. Then nourish yin and tonify yang, so that the patient's body is strong as before, and diabetes can be cured, so it can receive the curative effect of quick effect, short course of treatment, high cure rate and low recurrence rate. At the same time, the drug has no toxic and side effects, and has a unique curative effect on obesity, high blood pressure, high blood fat, and fatty liver. It can also receive good effects on weight loss, beauty, and diabetes prevention.

detailed description

The combined medicine for treating type Ⅱ diabetes of the present invention is made of the following medicines in parts by weight: 15-20 parts of astragalus, 15-20 parts of ginseng, 10-15 parts of Ligustrum lucidum, 15-25 parts of wolfberry, coriander 10-15 parts of Atractylodes macrocephala, 15-20 parts of Rehmannia glutinosa, 15-20 parts of kudzu root, 8-10 parts of turmeric, 10-15 parts of gallinaceous gold, 8-10 parts of purslane, 8-10 parts of dandelion, and 5 parts of woody fragrance -8 parts, 20-30 parts of lichens, 20-30 parts of white radish leaves, 20-30 parts of sweet potato leaves, 15-20 parts of willow leaves, 15-20 parts of acacia leaves. Among them: white radish leaves and sweet potato leaves can be picked before the Mid-Autumn Festival, and willow leaves and acacia leaves can be picked before the Qingming solar term. ℃, or dry under vacuum at room temperature. After all the medicinal materials are prepared, they are crushed separately, passed through a 200-300 mesh sieve to make a fine powder and used directly or made into a water pill according to a conventional method. When taking it, take 9-15 grams each time, 3 times a day, after meals, and 30 days is a course of treatment.

Embodiment one

The combined medicine for treating type Ⅱ diabetes mellitus of the present invention, the weight ratio of each component can be: 15 parts of astragalus, 15 parts of ginseng, 10 parts of Ligustrum lucidum, 15 parts of medlar, 10 parts of Jiaobaizhu, Rehmannia glutinosa 15 parts, kudzu root 15 parts, turmeric 8 parts, gallinacea 10 parts, purslane 8 parts, dandelion 8 parts, woody 5 parts, lichen 20 parts, white radish leaves 20 parts, sweet potato leaves 20 parts, willow leaves 15 parts, 15 parts of acacia leaves.

Embodiment two

The combined medicine for the treatment of type Ⅱ diabetes of the present invention, the parts by weight of its components can also be: 18 parts of astragalus, 18 parts of ginseng, 13 parts of Ligustrum lucidum, 20 parts of medlar, 13 parts of Jiaobaizhu, 18 parts of Rehmannia glutinosa, 18 parts of kudzu root, 9 parts of turmeric, 13 parts of gallinaceous gold, 9 parts of purslane, 6 parts of dandelion, 6 parts of woody fragrance, 25 parts of lichen, 25 parts of white radish sprouts, 25 parts of sweet potato leaves, willow 17 parts of leaves, 17 parts of acacia leaves.

Embodiment three

The combined medicine for treating type Ⅱ diabetes mellitus of the present invention, the weight ratio of each component can also be: 20 parts of astragalus, 20 parts of ginseng, 15 parts of Ligustrum lucidum, 25 parts of medlar, 15 parts of Jiaobaizhu, 20 parts of Rehmannia glutinosa, 20 parts of kudzu root, 10 parts of turmeric, 15 parts of gallinacea, 10 parts of purslane, 10 parts of dandelion, 8 parts of woody fragrance, 30 parts of lichen, 30 parts of white radish sprouts, 30 parts of sweet potato leaves, willow 20 parts of leaves, 20 parts of acacia leaves.

Embodiment Four

15 parts of astragalus, 15 parts of ginseng, 10 parts of Ligustrum lucidum, 20 parts of medlar, 10 parts of Jiaobaizhu, 15 parts of Rehmannia glutinosa, 15 parts of kudzu root, 10 parts of turmeric, 15 parts of gallinaceous gold, 10 parts of purslane, dandelion 10 parts, 5 parts of woody fragrance, 30 parts of lichen, 30 parts of white radish leaves, 30 parts of sweet potato leaves, 20 parts of willow leaves, and 20 parts of acacia leaves. The protocol of this example is suitable for patients with early type Ⅱ diabetes and patients with obesity, hyperlipidemia and fatty liver.

Embodiment five

20 parts of astragalus, 20 parts of ginseng, 15 parts of Ligustrum lucidum, 25 parts of medlar, 10 parts of Jiaobaizhu, 20 parts of Rehmannia glutinosa, 20 parts of kudzu root, 8 parts of turmeric, 10 parts of gallinaceous gold, 8 parts of purslane, dandelion 8 parts, 8 parts of woody fragrance, 20 parts of lichen, 20 parts of white radish leaves, 20 parts of sweet potato leaves, 15 parts of willow leaves, and 15 parts of acacia leaves. The scheme of this embodiment is suitable for patients with type Ⅱ diabetes mellitus in the middle and late stages.

The drug combination of the present invention has been clinically tested in the First Affiliated Hospital of Nanyang Medical College since 2012, and has treated 128 diabetic patients, including 79 males, accounting for 61.7%; 49 females, accounting for 48.3%; the youngest 45 years old, the oldest was 79 years old, and the average age was 58 years old; 43 cases were 45-55 years old, 52 cases were 55-65 years old, and 33 cases were over 65 years old; the shortest course of disease was 6 months, and the longest was 10 years and 3 months The average course of disease was 6 years and 5 months. After drug treatment of the present invention, symptoms such as diabetes, hypertension, and hyperlipidemia disappeared completely, and 112 cases were stable without recurrence, and the cure rate was 87.5%; 8 cases were partially improved by the symptoms, and the total effective rate was 93.8%; There were 8 cases of recurrence after 1 year of taking the medicine, and the recurrence rate was 7.1%.

Typical cases

Case 1

Chen, male, 36 years old, self-employed owner in Tanghe County, Nanyang City, first visit on March 6, 2012, self-reported diabetes for half a year, dizziness, headache, limb weakness, lack of energy, hospital diagnosis of fasting blood sugar 11.0, no urine sugar, glycosylation Hemoglobin 6.3, fasting insulin 5.4, the body is fat. The method of taking the medicine is 10g each time, three times a day, once in the morning, lunch and dinner. After taking the medicine for three courses, after the hospital examination, all the indicators returned to normal, and the subjective symptoms disappeared; After each time, the weight loss was 9kg, and the body and mind were healthy. After three years of follow-up visits, all indicators did not rebound after drug withdrawal.

Case 2

Zhang, female, 62 years old, a retired cadre in Neixiang County, Nanyang City. The patient reported that she had been suffering from diabetes for about 7 years. She felt weak, had frequent urination, low back pain and easy sprains. She went to the hospital to check urine sugar++ and fasting blood sugar. 8.7, no treatment measures are taken, and self-control diet is maintained. Until July 2012, the patient suddenly developed symptoms such as blurred vision, pain in hands and feet, palpitation, shortness of breath, itching all over the body, mouth ulcers, insomnia, fatigue, and rash. Diagnosed with type 2 diabetes by a city-level hospital, hospitalized, taking insulin Novolin twice a day, 26 units of Novolin half an hour before lunch, and 22 units of Novolin before meals in the afternoon. Complications did not decrease but increased (urinary protein ++++, urine sugar ++++, premature heartbeat, arrhythmia, multiple hepatic and renal cysts, 1/3 tooth loss and cloudy eyes. The person is yellow and black and thin, weighing one Within a month, she lost 20kg sharply, lacked energy and speech, insomnia and anxiety, and lost confidence in healing. On March 5, 2013, she came to the hospital for treatment. The clinical body was blue and gray, scorched and emaciated, whispering and lazy. , fishy mouth and bad breath. The doctor's advice is to take the combination medicine of the present invention, each 15g, every day 3 times, take after morning, noon and dinner, and stop injecting insulin. After taking the medicine for 40 days, the patient's drinking water and nocturia decreased, hypoglycemia disappeared, and the remaining symptoms disappeared After continuing to take the medicine for four months, the clinical symptoms disappeared, and the mental state was greatly improved. The physical and chemical indicators of glycosylated hemoglobin were 6.8, urine protein and fatty liver disappeared, urine sugar was +, and the weight increased by 3kg. The patient's confidence was greatly increased. The doctor ordered to continue taking medicine Maintenance, 10g each time, once a day in the morning and evening, after taking 4 courses of treatment, after reexamination, the patient's physical and chemical indicators were normal, vision, heart, etc. returned to normal, after B-ultrasound examination, liver and kidney cysts disappeared, and the body returned to health. Return visit for three years, no repeat.

Case 3

He Mou, male, 72 years old, a farmer in Nanzhao County, Nanyang City, came to see a doctor on August 2, 2014. He reported diabetes for 10 years, subjective symptoms of fatigue, dry mouth and thirst, frequent urination, high blood pressure, and hyperlipidemia. The human body is haggard, black and thin, mentally exhausted, and under heavy pressure. Long-term use of oral insulin, metformin and other hypoglycemic drugs has poor effects. Take the combination medicine of the present invention, each 15g, every day 3 times, respectively obey once in the morning, middle and evening meals. After taking three courses of treatment, the symptoms of dry mouth, thirst, polyuria and frequent urination were alleviated, and blood pressure returned to normal; after taking the medicine for three courses, all indicators returned to normal after hospital examination, and all the subjective symptoms disappeared; 10g each time, 2 times a day, once in the morning and evening after meals. After a follow-up visit for three years, her complexion was radiant, her body and mind were healthy, and all indicators did not rebound after stopping the drug.

Case 4

Li, male, 49 years old, a self-employed merchant in Wolong District, Nanyang City, came to the hospital for treatment on July 9, 2012, and reported that he had been obese for 7 years, with chest tightness, fatigue, wheezing when sitting and lying down, and frequent chest pains, severe affect labor. Clinical examination, height 1.68m, weight 106.5kg, and hypertension, hyperlipidemia, fatty liver, edema embolism. Take the combination medicine of the present invention according to the doctor's order, each 15g, 3 times a day, take it after morning, noon and dinner, and stop eating greasy, alcoholic beverages. After taking the medicine for 30 days, the body weight decreased by 4.2kg, and the subjective symptoms such as wheezing and chest pain disappeared; After a course of treatment, the body weight was reduced by 15kg after examination, and symptoms such as fatigue, high blood pressure, high blood fat, fatty liver, and edema disappeared, and she moved freely. The doctor ordered to continue to take the medicine, 10g each time, once a day after breakfast and dinner, limit greasy food, avoid drinking alcohol and water; after another six courses of treatment, after examination, the weight was reduced to 72kg, the body was normal, the spirit was restored, the work was vigorous, and the spirit was hale and hearty , very happy; a return visit a year later, the weight was reduced to 67kg, and there was no rebound.

Finally, it is noted that the above embodiments are only used to illustrate the technical solution of the present invention without limitation, other modifications or equivalent replacements made by those skilled in the art to the technical solution of the present invention, as long as they do not depart from the spirit and spirit of the technical solution of the present invention All should be included in the scope of the claims of the present invention.

Claims (6)

1. A combined medicine for the treatment of type Ⅱ diabetes, characterized in that: it is made of the following medicines in parts by weight: 15-20 parts of Radix Astragali, 15-20 parts of Radix Ginseng, 10-15 parts of Ligustrum lucidum, Lycium barbarum 15-25 parts, 10-15 parts of Jiaobaizhu, 15-20 parts of rehmannia glutinosa, 15-20 parts of kudzu root, 8-10 parts of turmeric, 10-15 parts of gallinaceous gold, 8-10 parts of purslane, 8- dandelion 10 parts, 5-8 parts of woody fragrance, 20-30 parts of lichen, 20-30 parts of white radish leaves, 20-30 parts of sweet potato leaves, 15-20 parts of willow leaves, 15-20 parts of acacia leaves. 2. the combined medicine for the treatment of type 2 diabetes as claimed in claim 1, characterized in that: it is made of the following medicines by weight: 15 parts of astragalus, 15 parts of ginseng, 10 parts of Ligustrum lucidum, 20 parts of medlar, 10 parts of Jiaobaizhu, 15 parts of Rehmannia glutinosa, 15 parts of kudzu root, 10 parts of turmeric, 15 parts of gallinaceous gold, 10 parts of purslane, dandelion 10 parts, 5 parts of woody fragrance, 30 parts of lichen, 30 parts of white radish leaves, 30 parts of sweet potato leaves, 20 parts of willow leaves, and 20 parts of acacia leaves. 3. The combined medicine for treating type Ⅱ diabetes as claimed in claim 1, characterized in that: it is made from the following medicines by weight: 20 parts of astragalus, 20 parts of ginseng, 15 parts of Ligustrum lucidum, 25 parts of medlar, 10 parts of Jiaobaizhu, 20 parts of Rehmannia glutinosa, 20 parts of kudzu root, 8 parts of turmeric, 10 parts of gallinaceous gold, 8 parts of purslane, dandelion 8 parts, 8 parts of woody fragrance, 20 parts of lichen, 20 parts of white radish leaves, 20 parts of sweet potato leaves, 15 parts of willow leaves, and 15 parts of acacia leaves. 4. The combined medicine for treating type 2 diabetes according to any one of claims 1-3, characterized in that: the white radish leaves and sweet potato leaves are picked before the Mid-Autumn Festival, and the willow leaves and acacia leaves are picked before the Qingming Festival. pick. 5. The combined medicine for treating type 2 diabetes according to any one of claims 1-3, characterized in that: the white radish leaves, sweet potato leaves, willow leaves and acacia leaves are dried at low temperature, and the drying temperature is not over 50°C. 6. The combined medicine for treating type 2 diabetes according to any one of claims 1-3, characterized in that: the white radish leaves, sweet potato leaves, willow leaves and acacia leaves are vacuum-dried at room temperature.