CN106548020A - Automatic prompting system for drug interference on test results of test items - Google Patents
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- 230000002452 interceptive effect Effects 0.000 claims description 5
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- 238000012986 modification Methods 0.000 description 2
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Abstract
Description
技术领域technical field
本发明涉及药物对检验项目检测结果干扰的自动提示系统,主要涉及临床检验医学中药物对检验项目检测结果干扰的提示装置。The invention relates to an automatic prompting system for the interference of drugs on the test results of test items, and mainly relates to a prompt device for the interference of drugs on the test results of test items in clinical laboratory medicine.
背景技术Background technique
临床检验医学是医学科学的重要组成部分,各种检验结果为临床疾病的诊断治疗提。因此,保证检验结果的准确性和可靠性是临床实验室质量管理的核心问题。国内外究报道,某些治疗药物可以影响血液中多种成分浓度的检测,呈现正干扰或负干扰。治疗药物对检验结果的分析干扰是一个重要的普遍存在的问题,不仅导致对检验结果错误解释、误诊、而且使患者承受不必要的进一步检查,增加了患者的的医疗费用,给患者的诊断和治疗存在不利的影响,但国内对此尚未引起足够的重视,相关的文献报道也不多,无论检验工作者和临床医师在解释实验室检测结果时,均未考虑到药物的影响。此外,检验工作者通常不能实时了解临床的用药情况,临床医生也不了解哪些药物会对哪些检验项目造成干扰,因此,造成检验结果的准确性和可靠性不够满意的问题。Clinical laboratory medicine is an important part of medical science, and various test results provide guidance for the diagnosis and treatment of clinical diseases. Therefore, ensuring the accuracy and reliability of test results is the core issue of clinical laboratory quality management. Domestic and foreign studies have reported that some therapeutic drugs can affect the detection of the concentration of various components in blood, showing positive or negative interference. The interference of therapeutic drugs on the analysis of test results is an important and common problem, which not only leads to misinterpretation and misdiagnosis of test results, but also makes patients suffer from unnecessary further examinations, which increases the medical expenses of patients, and the diagnosis and treatment of patients. There are adverse effects of treatment, but this has not been paid enough attention in China, and there are not many related literature reports. Neither laboratory workers nor clinicians have considered the influence of drugs when interpreting laboratory test results. In addition, laboratory workers usually cannot understand the clinical drug use in real time, and clinicians do not know which drugs will interfere with which test items. Therefore, the accuracy and reliability of the test results are not satisfactory.
发明内容Contents of the invention
本发明的目的是提供药物对检验项目检测结果干扰的自动提示系统,它嵌入到现有医院的医院信息管理系统HIS或者实验室信息管理系统LIS中,能及时给临床医生和检验工作者进行相关提示,对于减少药物对检验项目的干扰,提高检测结果的准确性和可靠性,为临床医生的诊断提供更有力的数据支持。The purpose of the present invention is to provide an automatic reminder system for the interference of drugs on the test results of test items. It is embedded in the hospital information management system HIS or laboratory information management system LIS of the existing hospital, and can provide relevant information to clinicians and test workers in time. It is suggested that to reduce the interference of drugs on test items, improve the accuracy and reliability of test results, and provide more powerful data support for clinicians' diagnosis.
本发明的目的是通过如下技术方案来实现的:The purpose of the present invention is achieved through the following technical solutions:
药物对检验项目检测结果干扰的自动提示系统,包括安装在医院信息管理系统HIS或者实验室信息管理系统LIS中的药物干扰检验自动提示程序模块,该药物干扰检验自动提示程序模块主要包括数据库系统,该数据库系统针对每个检验项目收集对其检验结果产生干扰的药物而形成,在临床医生开具检验项目检查医嘱时或在完成的检验报告时自动调用上述的数据库系统,并在数据库系统上查找到对该检验项目检测结果产生干扰的药物,然后显示药物干扰提示信息。The automatic reminder system for the interference of drugs on the test results of test items includes an automatic reminder program module for drug interference testing installed in the hospital information management system HIS or laboratory information management system LIS. The automatic reminder program module for drug interference testing mainly includes a database system, The database system is formed by collecting drugs that interfere with the test results for each test item. When the clinician issues a test item inspection doctor's order or when the test report is completed, the above-mentioned database system is automatically invoked, and found on the database system. For drugs that interfere with the test result of the test item, a drug interference prompt message will be displayed.
上述药物干扰提示信息包括对检验结果产生正干扰的药物和对检验结果产生负干扰的药物。The above drug interference prompt information includes drugs that positively interfere with test results and drugs that negatively interfere with test results.
上述的药物干扰检验自动提示程序模块还包括比对单元,比对单元在医院信息管理系统HIS中查找到近期病人临床用药的情况并与数据库系统中的干扰药物进行对比分析,进一步提示病人近期临床用药对检验项目检测结果产生正干扰或者负干扰。The above-mentioned automatic reminder program module for drug interference test also includes a comparison unit, which finds the recent clinical drug use of patients in the hospital information management system HIS and compares and analyzes it with the interfering drugs in the database system to further remind the patient of recent clinical symptoms. Drugs have positive or negative interference on the test results of the test items.
上述的医院信息管理系统HIS包含若干个供临床医生使用的医生计算机终端系统,当临床医生在医生计算机终端系统开具检验项目检查医嘱时,药物干扰检验自动提示程序模块启动,并在该医生计算机终端系统显示该检验项目检测结果产生干扰的药物的提示信息,临床医生在了解病人近期的用药情况下,结合该检验项目检测结果产生干扰的药物的提示信息,决定是否提交该检验项目的请求。The above-mentioned hospital information management system HIS includes several doctor computer terminal systems for clinicians. When the clinician issues a doctor’s order for inspection items on the doctor computer terminal system, the drug interference test automatic prompt program module starts, and the computer terminal of the doctor The system displays the reminder information of the drug that interferes with the test result of the test item, and the clinician decides whether to submit the request for the test item based on the patient’s recent drug use and the prompt information of the drug that interferes with the test result of the test item.
上述所述的实验室信息管理系统LIS在出具针对某个检验项目的检验报告时,会启动药物干扰检验自动提示程序模块,自动将对上述检验项目检测结果产生干扰的药物的提示信息写入检验报告中,以供医生查考。When the laboratory information management system LIS mentioned above issues an inspection report for a certain inspection item, it will start the automatic reminder program module for drug interference inspection, and automatically write the reminder information of the drug that interferes with the test results of the above inspection items into the inspection report. In the report, for the doctor's review.
本发明与现有技术相比具有如下优点:Compared with the prior art, the present invention has the following advantages:
1)本发明公开了药物对检验项目检测结果干扰的自动提示系统,包括药物干扰检验自动提示程序模块,该药物干扰检验自动提示程序模块主要包括数据库系统,该数据库系统针对每个检验项目收集对其检验结果产生干扰的药物而形成,在临床医生开具检验项目检查医嘱时或在完成的检验报告时自动调用上述的数据库系统,在数据库系统上查找到对该检验项目检测结果产生干扰的药物,然后显示药物干扰提示信息,以避免对临床的诊疗造成误诊,减少患者不必要的检测费用,提示临床停药或改用其他药物后再进行检测。可以极好地保证检测结果的准确性。1) The present invention discloses an automatic reminder system for the interference of drugs on the test results of inspection items, including an automatic reminder program module for drug interference inspection. The automatic reminder program module for drug interference inspection mainly includes a database system. It is formed by drugs that interfere with the test results. When the clinician issues a doctor's order for the test item or when the test report is completed, the above-mentioned database system is automatically called, and the drug that interferes with the test result of the test item is found on the database system. Then display drug interference prompt information to avoid misdiagnosis of clinical diagnosis and treatment, reduce unnecessary testing costs for patients, and prompt clinical drug withdrawal or switch to other drugs before testing. Can excellently guarantee the accuracy of the test results.
2)物干扰提示信息包括对检验结果产生正干扰的药物和对检验结果产生负干扰的药物。提示效果更佳,有利于提示临床停药或改用其他药物后再进行检测。2) The drug interference prompt information includes drugs that positively interfere with the test results and drugs that negatively interfere with the test results. The prompting effect is better, and it is beneficial to prompt clinical drug withdrawal or switch to other drugs before testing.
3)上述的药物干扰检验自动提示程序模块还包括比对单元,比对单元在医院信息管理系统HIS中查找到近期病人临床用药的情况并与数据库系统中的干扰药物进行对比分析,进一步提示病人近期临床用药对检验项目检测结果产生正干扰或者负干扰,以利用医生对检验项目检测结果的准确性、可信性做一个较好的评估。3) The above-mentioned automatic reminder program module for drug interference test also includes a comparison unit, which finds the recent clinical drug use of patients in the hospital information management system HIS and compares and analyzes it with the interfering drugs in the database system to further remind the patient The recent clinical medication has positive or negative interference on the test results of the test items, so that doctors can make a better assessment of the accuracy and reliability of the test results.
附图说明Description of drawings
图1为现有医院中检验项目的信息流向方框图;Fig. 1 is a block diagram of information flow of inspection items in existing hospitals;
图2为现有实验室的自动化流水线检测系统的方框图;Fig. 2 is the block diagram of the automatic assembly line inspection system of existing laboratory;
图3是本发明的临床医生开具检验项目检查医嘱时的流程图;Fig. 3 is the flowchart when the clinician of the present invention issues the inspection item inspection doctor's order;
图4为本发明的医院信息管理系统HIS完成检验报告时流程图。Fig. 4 is a flow chart when the hospital information management system HIS of the present invention completes the inspection report.
图5是为本发明的药物对检验项目检测结果干扰的自动提示系统的组成结构图。Fig. 5 is a structural diagram of the automatic reminder system for the interference of the medicine on the test result of the test item according to the present invention.
具体实施方式detailed description
为使本发明实施例的目的、技术方案和优点更加清楚,下面将结合本发明实施例中的附图,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments It is a part of embodiments of the present invention, but not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.
如图1所示,本发明的医院信息管理系统HIS与实验室信息管理系统LIS进行连接和通信,医院信息管理系统HIS包括许多子系统组成,例如:医生计算机终端系统、计费系统、药物物流系统等,在此不再叙述;临床医生开具检验项目检查医嘱是通过医生计算机终端系统来实现。实验室信息管理系统LIS接收医院信息管理系统HIS发送过来的检验项目请求,经过实验室的检验设备采集检测数据后形成检验报告,然后实验室信息管理系统LIS将检验报告发回医院信息管理系统HIS,临床医生通过医生计算机终端系统可以查看检验报告,阅读检验结果。目前的大医院的实验室都都基本实验检验自动化,包括实验室流水线数据管理系统和实验室流水线检测系统,实验室流水线数据管理系统控制实验室流水线检测系统,实验室流水线数据管理系统与实验室信息管理系统LIS连接通信。As shown in Figure 1, the hospital information management system HIS of the present invention is connected and communicated with the laboratory information management system LIS. The hospital information management system HIS includes many subsystems, such as: doctor computer terminal system, billing system, drug logistics The system, etc., will not be described here; the doctor's order for inspection items and inspections issued by clinicians is realized through the doctor's computer terminal system. The laboratory information management system LIS receives the inspection item request sent by the hospital information management system HIS, and forms an inspection report after the inspection data is collected by the laboratory inspection equipment, and then the laboratory information management system LIS sends the inspection report back to the hospital information management system HIS , Clinicians can check the test report and read the test results through the doctor's computer terminal system. At present, the laboratories of large hospitals are basically automated in experimental testing, including laboratory assembly line data management system and laboratory assembly line detection system, laboratory assembly line data management system controls laboratory assembly line detection system, laboratory assembly line data management system and laboratory Information management system LIS connection communication.
如图2所示,本发明所提供的流水线检测系统包括轨道传送模块、进样和出样模块、预分析处理模块、多台流水线分析仪器以及后分析处理模块,轨道传送模块把进样和出样模块、预分析处理模块、多台流水线分析仪器以及后分析处理模块依次连接起来;As shown in Figure 2, the assembly line detection system provided by the present invention includes a rail transport module, a sample feeding and sample discharging module, a pre-analysis processing module, a plurality of pipeline analysis instruments and a post analysis processing module, and the rail transfer module transfers the sample feeding and sample discharging The sample module, pre-analysis and processing module, multiple pipeline analysis instruments and post-analysis and processing modules are connected in sequence;
所述流水线检测系统中,轨道传送模块将样本试管从进样和出样模块移到多台流水线分析仪器,然后移到后分析处理模块。In the pipeline detection system, the track transport module moves the sample test tubes from the sample injection and sample discharge modules to multiple pipeline analysis instruments, and then to the post-analysis and processing module.
进样和出样模块是流水线检测系统的中心组件。流水线检测系统含有至少一个进样和出样模块。进样和出样模块通过可配置的输入和输出输送道装载和卸载样本试管。The sampling and sampling module is the central component of the pipeline inspection system. The pipeline detection system includes at least one sample injection and sample output module. The sample injection and output modules load and unload sample tubes through configurable input and output conveyors.
所述预分析处理模块包括离心模块、去盖模块、去膜模块以及分杯模块。预分析处理模块提供流水线检测系统需要的额外功能,例如离心、去盖、解除密封、以及样本等分。其中离心模块可以对样本进行自动离心分离,去盖模块可以拆开主样本试管的塑料螺旋盖和压力封盖,去膜模块可以去除被封膜模块密封的样本试管上的铝箔密封,分杯模块可以通过现有主样本试管产生辅助样本试管。The pre-analysis and processing module includes a centrifugation module, a cap removal module, a film removal module and a cupping module. The Pre-Analytical Processing module provides additional functions required by pipeline testing systems, such as centrifugation, decapping, desealing, and sample aliquoting. Among them, the centrifuge module can automatically centrifuge the samples, the cover removal module can disassemble the plastic screw cap and pressure cover of the main sample test tube, the membrane removal module can remove the aluminum foil seal on the sample test tube sealed by the film sealing module, and the cupping module Secondary sample tubes can be created from existing primary sample tubes.
多台流水线分析仪器是流水线检测系统1的关键仪器,根据需求用于检测、分析样本试管的相关数据。A plurality of pipeline analysis instruments are the key instruments of the pipeline detection system 1, which are used to detect and analyze relevant data of sample test tubes according to requirements.
所述后分析处理模块包括封膜模块、子管回盖模块以及冷冻储存模块,进而完成自动处理循环。在分析和处理后,封膜模块使用铝箔卷上的铝箔来密封试管。将铝箔密封片切割,然后热封到每个塑料样本试管上。每个铝箔卷含有16,000个密封片。子管回盖模块可以将螺旋盖放在分杯模块产生的辅助样本试管上。冷冻储存模块将密封的样本试管保存在温度受控的环境中,它含有储存工作台和自动冷冻机(可以是恒温冰箱)。The post-analysis processing module includes a sealing film module, a sub-tube capping module, and a frozen storage module, thereby completing an automatic processing cycle. After analysis and processing, the sealing module uses aluminum foil on a foil roll to seal the tubes. Aluminum foil seals were cut and heat sealed to each plastic sample tube. Each foil roll contains 16,000 seals. The sub-tube capping module can place screw caps on auxiliary sample tubes produced by the sub-cupping module. The refrigerated storage module stores sealed sample tubes in a temperature-controlled environment and contains storage benches and automated freezers (which can be thermostatic refrigerators).
如图3、图4所示,本发明的药物对检验项目检测结果干扰的自动提示系统,包括安装在医院信息管理系统HIS或者实验室信息管理系统LIS中的药物干扰检验自动提示程序模块,该药物干扰检验自动提示程序模块主要包括数据库系统,该数据库系统针对每个检验项目收集对其检验结果产生干扰的药物而形成,在临床医生开具检验项目检查医嘱时或在完成的检验报告时自动调用上述的数据库系统,并在数据库系统上查找到对该检验项目检测结果产生干扰的药物,然后显示药物干扰提示信息。As shown in Fig. 3 and Fig. 4, the automatic reminder system for the interference of the medicine on the test item test result of the present invention includes an automatic reminder program module for the drug interference inspection installed in the hospital information management system HIS or the laboratory information management system LIS, the The automatic reminder program module for drug interference test mainly includes a database system, which is formed by collecting drugs that interfere with the test results for each test item, and is automatically invoked when the clinician issues a test item inspection order or when the test report is completed The above-mentioned database system, and find the drug that interferes with the test result of the test item on the database system, and then display the drug interference prompt information.
药物干扰提示信息包括对检验结果产生正干扰的药物和对检验结果产生负干扰的药物。药物干扰检验自动提示程序模块还包括比对单元,比对单元在医院信息管理系统HIS中查找到近期病人临床用药的情况并与数据库系统中的干扰药物进行对比分析,进一步提示病人近期临床用药对检验项目检测结果产生正干扰或者负干扰。The drug interference prompt information includes drugs that positively interfere with test results and drugs that negatively interfere with test results. The automatic reminder program module for drug interference test also includes a comparison unit, which finds the recent clinical drug use of patients in the hospital information management system HIS and compares and analyzes it with the interfering drugs in the database system, further reminding the patient of the recent clinical drug use. The test results of the test items produce positive or negative interference.
医院信息管理系统HIS包含若干个供临床医生使用的医生计算机终端系统,当临床医生在医生计算机终端系统开具检验项目检查医嘱时,药物干扰检验自动提示程序模块启动,并在该医生计算机终端系统显示该检验项目检测结果产生干扰的药物的提示信息,临床医生在了解病人近期的用药情况下,结合该检验项目检测结果产生干扰的药物的提示信息,决定是否提交该检验项目的请求。The hospital information management system HIS includes several doctor computer terminal systems for clinicians. When the clinician issues a doctor's order for inspection items on the doctor computer terminal system, the automatic prompt program module for drug interference testing starts and is displayed on the doctor computer terminal system. The prompt information of the drug that interferes with the test result of the test item. The clinician decides whether to submit the request for the test item after knowing the patient’s recent drug use and combining the prompt information of the drug that interferes with the test result of the test item.
上述的实验室信息管理系统LIS在出具针对某个检验项目的检验报告时,会启动药物干扰检验自动提示程序模块,自动将对上述检验项目检测结果产生干扰的药物的提示信息写入检验报告中,以供医生查考。When the above-mentioned laboratory information management system LIS issues a test report for a certain test item, it will start the drug interference test automatic prompt program module, and automatically write the prompt information of the drug that interferes with the test results of the above test item into the test report , for the doctor to check.
本发明在临床医生开具检验项目时,可实时读取临床用药情况,并可根据数据库的情况实时提示临床医生在使用的药物会对某项检验项目造成正干扰或负干扰,或者实验室信息管理系统LIS在完成检验报告时,可在出具检验报告时实时读取标本采集时间及用药情况,自动在检验报告上备注干扰情况,提示临床停药或改用其他药物后再进行检测。本发明的药物对检验项目检测结果干扰的自动提示系统可以极好地保证检测结果的准确性。目前国内尚未见相关本发明内容的研究报道。The present invention can read the clinical medication situation in real time when the clinician prescribes the test item, and can prompt the clinician in real time according to the situation of the database that the medicine used by the clinician will cause positive or negative interference to a certain test item, or laboratory information management When the system LIS completes the test report, it can read the sample collection time and medication status in real time when the test report is issued, and automatically note the interference on the test report, prompting clinical withdrawal or switching to other drugs before testing. The automatic prompting system for the interference of the medicine on the test result of the test item of the present invention can excellently guarantee the accuracy of the test result. There is no research report related to the content of the present invention in China at present.
该药物干扰检验自动提示程序模块主要包括数据库系统,该数据库系统针对每个检验项目收集对其检验结果产生干扰的药物而形成,该数据库包括如下字段:检验项目名称、正干扰药物和负干扰药物,如表1所示,当临床医生在医生计算机终端系统开具检验项目检查医嘱时,药物干扰检验自动提示程序模块启动,并在该医生计算机终端系统显示该检验项目检测结果产生干扰的药物的提示信息,当然临床医生也可在医院信息管理系统HIS中可以查找到患者ID号(即身份识别号)、即将进行或者已经完成的检测项目、患者正在用药名称、起始用药和结束用药时间和剂量等相关信息,临床医生根据这些信息进行判断,也可以利用药物干扰检验自动提示程序模块还包括比对单元,比对单元在医院信息管理系统HIS中查找到近期病人临床用药的情况并与数据库系统中的干扰药物进行对比分析,进一步提示病人近期临床用药对检验项目检测结果产生正干扰或者负干扰。The automatic reminder program module for drug interference test mainly includes a database system, which is formed by collecting drugs that interfere with the test results for each test item. The database includes the following fields: test item name, positive interference drug and negative interference drug , as shown in Table 1, when a clinician issues a doctor’s order for inspection items on the doctor’s computer terminal system, the drug interference inspection automatic reminder program module starts, and the doctor’s computer terminal system displays the reminder of the drug that interferes with the test result of the inspection item Of course, clinicians can also find the patient ID number (identification number), upcoming or completed test items, the name of the patient who is taking medication, the time and dose of starting and ending medication in the hospital information management system HIS And other relevant information, clinicians can make judgments based on these information, and can also use the drug interference test to automatically prompt the program module. It also includes a comparison unit, which finds the recent clinical drug use of patients in the hospital information management system HIS and compares it with the database system The interfering drugs in the test were compared and analyzed to further prompt the patient's recent clinical medication to have positive or negative interference on the test results of the test items.
表1Table 1
如图5所示,药物干扰检验自动提示程序模块主要包括接口启动单元、数据库系统、比对单元,当检测到临床医生在医生计算机终端系统开具检验项目检查医嘱时或者者实验室信息管理系统LIS在完成检验报告时,自动启动接口启动单元并获取患者ID号(即身份识别号)、即将进行或者已经完成的检测项目等信息,然后启动数据库系统,并在数据库系统上查找到对该检验项目检测结果产生干扰的药物,然后显示药物干扰提示信息。或者接口启动单元先通知比对单元,比对单元在医院信息管理系统HIS中可以查找到患者ID号(即身份识别号)、即将进行或者已经完成的检测项目、患者正在用药名称、起始用药和结束用药时间和剂量等相关信息,然后调用数据库系统,利用检测项目去查找到产生干扰的药物名称,将产生干扰的药物名称再与患者正在用药名称对比,并来判断起始用药和结束用药时间和剂量等相关信息,得出提示信息。As shown in Figure 5, the automatic reminder program module for drug interference testing mainly includes an interface startup unit, a database system, and a comparison unit. When the inspection report is completed, the interface startup unit is automatically started and information such as the patient ID number (identification number), upcoming or completed inspection items is obtained, and then the database system is started, and the inspection item is found on the database system Drugs that interfere with the detection results, and then display drug interference prompts. Or the interface start unit first notifies the comparison unit, and the comparison unit can find the patient ID number (identification number), the test items to be carried out or completed, the name of the patient's medication, and the initial medication in the hospital information management system HIS and related information such as the time and dosage of the drug, and then call the database system, use the detection items to find the name of the drug that interferes, compare the name of the drug that caused the interference with the name that the patient is taking, and judge the starting and ending of the drug Relevant information such as time and dose can be used to obtain prompt information.
最后应说明的是:以上实施例仅用以说明本发明的技术方案,而非对其限制;尽管参照前述实施例对本发明进行了详细的说明,本领域的普通技术人员应当理解:其依然可以对前述各实施例所记载的技术方案进行修改,或者对其中部分技术特征进行等同替换;而这些修改或者替换,并不使相应技术方案的本质脱离本发明各实施例技术方案的精神和范围。Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: it can still be Modifications are made to the technical solutions described in the foregoing embodiments, or equivalent replacements are made to some of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the various embodiments of the present invention.
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