CN106539084A - One kind improves memory health food and preparation method thereof - Google Patents
One kind improves memory health food and preparation method thereof Download PDFInfo
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- CN106539084A CN106539084A CN201610991226.1A CN201610991226A CN106539084A CN 106539084 A CN106539084 A CN 106539084A CN 201610991226 A CN201610991226 A CN 201610991226A CN 106539084 A CN106539084 A CN 106539084A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 7
- DATAGRPVKZEWHA-YFKPBYRVSA-N N(5)-ethyl-L-glutamine Chemical compound CCNC(=O)CC[C@H]([NH3+])C([O-])=O DATAGRPVKZEWHA-YFKPBYRVSA-N 0.000 claims abstract description 64
- 239000000284 extract Substances 0.000 claims abstract description 63
- 229940026510 theanine Drugs 0.000 claims abstract description 31
- TZCPCKNHXULUIY-RGULYWFUSA-N 1,2-distearoyl-sn-glycero-3-phosphoserine Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC TZCPCKNHXULUIY-RGULYWFUSA-N 0.000 claims abstract description 29
- ZWZWYGMENQVNFU-UHFFFAOYSA-N Glycerophosphorylserin Natural products OC(=O)C(N)COP(O)(=O)OCC(O)CO ZWZWYGMENQVNFU-UHFFFAOYSA-N 0.000 claims abstract description 29
- 239000002994 raw material Substances 0.000 claims abstract description 24
- 239000009429 Ginkgo biloba extract Substances 0.000 claims abstract description 23
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 23
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 23
- 235000008434 ginseng Nutrition 0.000 claims abstract description 23
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- 235000013305 food Nutrition 0.000 claims description 19
- 238000005469 granulation Methods 0.000 claims description 12
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- DWNBOPVKNPVNQG-LURJTMIESA-N (2s)-4-hydroxy-2-(propylamino)butanoic acid Chemical compound CCCN[C@H](C(O)=O)CCO DWNBOPVKNPVNQG-LURJTMIESA-N 0.000 claims 1
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 abstract description 14
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- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
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- ZIIUUSVHCHPIQD-UHFFFAOYSA-N 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide Chemical compound CC1=CC(C)=CC(C)=C1S(=O)(=O)NC1=CC=CC(C(F)(F)F)=C1 ZIIUUSVHCHPIQD-UHFFFAOYSA-N 0.000 description 1
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- DATAGRPVKZEWHA-UHFFFAOYSA-N L-gamma-glutamyl-n-ethylamine Natural products CCNC(=O)CCC(N)C(O)=O DATAGRPVKZEWHA-UHFFFAOYSA-N 0.000 description 1
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- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical group CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 description 1
- 150000008104 phosphatidylethanolamines Chemical class 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- BZQFBWGGLXLEPQ-REOHCLBHSA-N phosphoserine Chemical compound OC(=O)[C@@H](N)COP(O)(O)=O BZQFBWGGLXLEPQ-REOHCLBHSA-N 0.000 description 1
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- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9062—Alpinia, e.g. red ginger or galangal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8988—Gastrodia
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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Abstract
The invention discloses one kind improves memory health food, phosphatidyl serine, theanine, Radix Ginseng Rubra extract, Rhizoma Gastrodiae extract, Fructus Alpinae Oxyphyllae extract, Ginkgo Biloba Extract and food additive Microcrystalline Cellulose and starch in its raw material, are included.By combining glucose metabolism in the mobility machine promotion brain cell for supplementing phosphatidyl serine increase brain bur number, raising brain cell membrane, so that brain cell is more active, the mechanism for promoting memory to concentrate；From the Radix Ginseng Rubra of strengthening the body resistance, improve the theanine of dopamine activity, being equipped with improves Rhizoma Gastrodiae extract, the Ginkgo Biloba Extract of memory, helped with the Fructus Schisandrae Chinensis extrat of supplementing QI for promoting the production of body fluid again and formed as Raw material processing, by strengthening the body resistance, run through blood brain barrier, affect the level of neurotransmitter and improve cerebral function, improve the purpose of memory.This product is safe and effective.The invention also discloses a kind of preparation method for improving memory health food.
Description
Technical field
The invention belongs to technical field of health care food, and in particular to one kind improves memory health food and its preparation side
Method.
Background technology
Hypomnesiss are a kind of dysmnesia, clinically more common, can show as subtracting for remote memory and nearly memory
Move back.It is mainly seen in cerebral organic psychosiss.
Also known as serinephosphatide, diacylglycerol acyl phosphoserine is the phospholipid of a class generally existing to phosphatidyl serine,
The internal layer of cell membrane is usually located at, the phosphoglycerol esters in phosphatide cpd, are one of cell membrane components, with a series of film work(
Can be relevant.Especially in the nervous system of human body.It is one of important composition composition of cell membrane of brain, while to each of brain
Kind of function (especially stablizing to the memory and emotion of brain) plays important adjustment effect, and such as it can affect cell membrane
Mobility, permeability, and the metabolism and synthesis of various enzymes can be activated.There is phosphatidylcholine if in human erythrocyte membrane
(accounting for 19%), sphingomyelins (accounting for 8%), PHOSPHATIDYL ETHANOLAMINE (accounting for 16%) and Phosphatidylserine (accounting for 10%).
Theanine (L-Theanine) is distinctive free amino acid in Folium Camelliae sinensis, and theanine is glutamic acid gamma-buserelin,
It is pleasantly sweet.Find in measure theanine position monoaminess (monoamine) metabolic effect each to brain, theanine can be obvious
Promote mesencephalic centre dopamine (dopamine) release, improve intracerebral dopamine physiologically active.Dopamine is a kind of activation cranial nerve
The central neurotransmitter of cell, its physiologically active are closely related with the emotion state of people.Although people to theanine in the brain
The mechanism of action of pivot nervous system is not fully aware of.But impact of the theanine to spirit and emotion is partly undoubtedly from right
The effect of central neurotransmitter dopamine physiologically active.Certainly antifatigue effect of drinking tea is recognized as to a certain extent from this
One effect.Yokogoshi et al. confirms that in their other experiments taking theanine can directly affect and learn, remember again
Recall the activity of relevant intracerebral central neurotransmitter 5-hydroxy tryptamine.
Rhizoma Gastrodiae is conventional Chinese medicine.Beginning is loaded in《Sheng Nong's herbal classic》, it is classified as top grade, original name " rhizoma gastrodiae ".It is because its stem is like arrow shaft, red
Color.There is flower at end, far sees that arrow such as has plumage, therefore named rhizoma gastrodiae.The name of Rhizoma Gastrodiae first appeared in《Leigong Paozhilun》.Rhizoma Gastrodiae extract is from orchid family
The brown color fine powdered substance extracted in the dry tuber of plant Rhizoma Gastrodiae Gastrodia elata Blume.Rhizoma Gastrodiae is to post
Plant, host are armillaria mellea.Sweet in the mouth；It is mild-natured.Inflammation Zhijing, suppressing the hyperactive liver and subsiding YANG.Shy for dizziness of having a headache, numb limbs and tense tendons, children
Wind, epilepsy clonus, tetanus.To treat the key medicine of dizziness, headache.
Fructus Schisandrae Chinensis extrat extracted is formed for the dry mature fruit of magnoliaceae schisandra.Sour in the mouth, it is sweet, it is warm in nature.
Return lung, heart channel.With astringent or styptic treatment for spontaneous sweating, the effect of supplementing QI for promoting the production of body fluid of convergence.Fructus Schisandrae Chinensis containing volatile oil, organic acid, vitamin, lignin, three
Various chemical compositions such as terpene and polysaccharide.Modern pharmacological research finds that schisandrol extract can be reduced because chemical substance causes
Serum transaminase rising is acted on, can obvious inducing mouse and rat liver microsomes cytochrome P-450 activity, the solution of enhancing liver
Malicious function, moreover it is possible to improve resistivity of the body to oxygen free radical injury, and the biological conjunction of hepatic protein and glycogen can be promoted
Into prompting Fructus Schisandrae Chinensis have good protective effect to chemical liver injury.The research such as Zhang Minghua shows that Fructus Schisandrae Chinensis are to four chlorinations
Serum glutamic pyruvic transminase caused by the hepatic injury that carbon, thioacetamide and second quinestrol are caused is raised has reduction to make
With while the high serum glutamic pyruvic transminase of hepatitis can also reduced.The hepatocyte histochemistry of animal shows that Fructus Schisandrae Chinensis can
Mitigate the chemical substance dysbolismus that toxics hepatitis are damaged, slightly increase hepatic glycogen, mitigate hepatic cell fattydegeneration, in mitigation
The pathogenic factor of poison is to stem cell mitochondrion and lysosomal destruction.The research such as Xu Keyu finds that Chinese magnoliavine fruit polysaccharide extract is to liver
Cell has significant protective effect, and this effect may be with its antagonism CCl4Lipid peroxidation pair caused by toxic metabolite
The damage of liver subcellular structure is relevant.Separately there are some researches show, Fructus Schisandrae Chinensis and its kernel ethanol extraction to carbon tetrachloride caused rabbit,
Rat and mouse liver injury cause glutamate pyruvate transaminase to raise obvious reduction effect, while can also be third turn of the high paddy of hepatitis
Ammonia enzyme is reduced, moreover it is possible to mitigate the substance metabolism obstacle of toxic liver injury, promotes the effect of hepatocyte internal protein.Pharmacopeia is recommended
Amount 2～6g/ days, Fructus Schisandrae Chinensis extrat withdrawal ratio are 10:1, it is 300g to be converted to crude drug amount, and this product consumption is 1.8g/ days.
It is existing improve memory health food in also do not find by take phosphatidyl serine, theanine, Radix Ginseng Rubra extract,
The health food that the raw materials such as Ginkgo Biloba Extract, Rhizoma Gastrodiae extract, Fructus Alpinae Oxyphyllae extract, Fructus Schisandrae Chinensis extrat compounding is constituted.
The content of the invention
It is an object of the present invention to provide one kind is with phosphatidyl serine, Radix Ginseng Rubra extract, theanine, Rhizoma Gastrodiae extract, Semen Ginkgo
Leaf extract, Fructus Alpinae Oxyphyllae extract, Fructus Schisandrae Chinensis extrat are main component with the health food for improving memory effect.
Present invention also offers a kind of preparation method for improving memory health food.
The present invention is adopted the following technical scheme that：
One kind improves memory health food, and phosphatidyl serine and theanine are included in the raw material of its food.
Further, also include in the raw material of the food Radix Ginseng Rubra extract, Rhizoma Gastrodiae extract, Fructus Alpinae Oxyphyllae extract,
Ginkgo Biloba Extract.
Further, food additive Microcrystalline Cellulose and starch are also included in the raw material of the food.
Further, the proportioning raw materials in the food are：
Phosphatidyl serine 60-180 weight portions
Radix Ginseng Rubra extract 50-140 weight portions
Theanine 10-100 weight portions
Rhizoma Gastrodiae extract 10-100 weight portions
Ginkgo Biloba Extract 10-100 weight portion
Fructus Alpinae Oxyphyllae extract 10-100 weight portions
Fructus Schisandrae Chinensis extrat 10-100 weight portions.
Further, the proportioning raw materials in the food are preferably：
Phosphatidyl serine 80-160 weight portions
Radix Ginseng Rubra extract 60-120 weight portions
Theanine 30-90 weight portions
Rhizoma Gastrodiae extract 30-90 weight portions
Ginkgo Biloba Extract 30-90 weight portion
Fructus Alpinae Oxyphyllae extract 30-90 weight portions
Fructus Schisandrae Chinensis extrat 30-90 weight portions.
Further, the proportioning raw materials in the food are preferably：
Phosphatidyl serine 100-140 weight portions
Radix Ginseng Rubra extract 80-100 weight portions
Theanine 40-80 weight portions
Rhizoma Gastrodiae extract 40-80 weight portions
Ginkgo Biloba Extract 40-80 part
Fructus Alpinae Oxyphyllae extract 40-80 weight portions
Fructus Schisandrae Chinensis extrat 40-80 weight portions.
Further, the proportioning raw materials in the food are preferably：
120 weight portion of phosphatidyl serine
90 weight portion of Radix Ginseng Rubra extract
60 weight portion of theanine
60 weight portion of Rhizoma Gastrodiae extract
60 weight portion of Ginkgo Biloba Extract
60 weight portion of Fructus Alpinae Oxyphyllae extract
60 weight portion of Fructus Schisandrae Chinensis extrat.
Further, the content of the raw material Phosphatidylserine in above-mentioned food must not be less than 10%.
Further, the food is tablet form.
A kind of a kind of preparation method for improving memory health food as above, comprises the steps：
1. dispensing：Take phosphatidyl serine 60-180 weight portions, Radix Ginseng Rubra extract 50-140 weight portions, theanine 10-100 weight
Part, Rhizoma Gastrodiae extract 10-100 weight portions, Ginkgo Biloba Extract 10-100 weight portion, Fructus Alpinae Oxyphyllae extract 10-100 weight portions,
Fructus Schisandrae Chinensis extrat 10-100 weight portions, then add starch 1-80 weight portions and Microcrystalline Cellulose 20-100 weight portion, mix 10-
Make which uniform within 30 minutes；
2. pelletize：With 70-90% ethanol soft materials, the granulation of 16 mesh sieves, 55-60 DEG C of drying, 14 mesh sieve granulate；
3. tabletting：Piece weight 0.6g/ pieces, control ambient temperature 18-25 DEG C, relative humidity 45%-60%；
4. coating：Bag uniform compact film-coat, controls ambient temperature 18-25 DEG C, relative humidity 45%-60%.
In above-mentioned raw materials, the Phosphatidylserine is turned with soybean lecithin and L-Serine as raw material using phospholipase
After changing reaction, purified concentration, then through secondarily purified, pack after being dried and be obtained.The content of Phosphatidylserine must not be less than
10%。
In above-mentioned raw materials, theanine carries out flocculation treatment, Jing macroporous resins point by primary raw material of tea polyphenols to tea polyphenols
Theanine is obtained from purification.Phosphatidyl serine and theanine compounding can be improved to improving memory action effect.Radix Ginseng Rubra is carried
It is with the enterprise for extracting production qualification to take thing, Ginkgo Biloba Extract, Fructus Alpinae Oxyphyllae extract, Rhizoma Gastrodiae extract, Fructus Schisandrae Chinensis extrat
Industry production is provided.This product increases brain bur number, improves brain with reference to phosphatidyl serine is supplemented in line with safely and effectively principle
The mobility machine of cell membrane promotes glucose metabolism in brain cell, so that brain cell is more active, the machine for promoting memory to concentrate
Reason, on the basis of with reference to amount of literature data, from the Radix Ginseng Rubra of strengthening the body resistance, improves the theanine of dopamine activity, is equipped with
Improve Rhizoma Gastrodiae extract, the Ginkgo Biloba Extract of memory, then help with the Fructus Schisandrae Chinensis extrat of supplementing QI for promoting the production of body fluid as Raw material processing
Into, by strengthening the body resistance, run through blood brain barrier, affect neurotransmitter level and improve cerebral function, improve memory
Purpose.
Specific embodiment
With reference to embodiment, the present invention is described in more detail.But skilled in the art realises that, following embodiments
It is not limiting the scope of the invention, any improvement made on the basis of the present invention and change, all in the guarantor of the present invention
Within the scope of shield.
Embodiment 1
Step one：Dispensing
Take 120 parts of phosphatidyl serine, 60 parts of theanine, 80 parts of Radix Ginseng Rubra extract, 40 parts of Ginkgo Biloba Extract, Rhizoma Gastrodiae extract
60 parts, 40 parts of Fructus Alpinae Oxyphyllae extract, 60 parts of Fructus Schisandrae Chinensis extrat, then add 80 parts of 60 parts of appropriate amount of starch and Microcrystalline Cellulose, mix
Conjunction makes uniform for 20 minutes.
Step 2：Granulation
With 85% ethanol soft material, the granulation of 16 mesh sieves, 55-60 DEG C of drying, 14 mesh sieve granulate.
Step 3：Tabletting
Tabletting, piece weight 0.6g/ pieces, controls ambient temperature 18-25 DEG C, relative humidity 45%-60%.
Step 4：Coating
Bag uniform compact film-coat, controls ambient temperature 18-25 DEG C, relative humidity 45%-60%.
Embodiment 2
Step one：Dispensing
Take 80 parts of 100 parts of phosphatidyl serine, 60 parts of theanine and Radix Ginseng Rubra extract, 60 parts of Ginkgo Biloba Extract, Rhizoma Gastrodiae extraction
60 parts of thing, 50 parts of Fructus Alpinae Oxyphyllae extract, 40 parts of Fructus Schisandrae Chinensis extrat, then add 90 parts of 60 parts of appropriate amount of starch and Microcrystalline Cellulose,
Mixing makes uniform for 20 minutes.
Step 2：Granulation
With 80% ethanol soft material, the granulation of 16 mesh sieves, 55-60 DEG C of drying, 14 mesh sieve granulate.
Step 3：Tabletting
Tabletting, piece weight 0.6g/ pieces, controls ambient temperature 18-25 DEG C, relative humidity 45%-60%.
Step 4：Coating
Bag uniform compact film-coat, controls ambient temperature 18-25 DEG C, relative humidity 45%-60%.
Embodiment 3
Step one：Dispensing
Take 100 parts of 180 parts of phosphatidyl serine, 80 parts of theanine and Radix Ginseng Rubra extract, 40 parts of Ginkgo Biloba Extract, Rhizoma Gastrodiae extraction
40 parts of thing, 40 parts of Fructus Alpinae Oxyphyllae extract, 40 parts of Fructus Schisandrae Chinensis extrat, then add 50 parts of 30 parts of appropriate amount of starch and Microcrystalline Cellulose,
Mixing makes uniform for 30 minutes.
Step 2：Granulation
With 85% ethanol soft material, the granulation of 16 mesh sieves, 55-60 DEG C of drying, 14 mesh sieve granulate.
Step 3：Tabletting
Tabletting, piece weight 0.6g/ pieces, controls ambient temperature 18-25 DEG C, relative humidity 45%-60%.
Step 4：Coating
Bag uniform compact film-coat, controls ambient temperature 18-25 DEG C, relative humidity 45%-60%.
Embodiment 4
Step one：Dispensing
Take 100 parts of 60 parts of phosphatidyl serine, 80 parts of theanine and Radix Ginseng Rubra extract, 80 parts of Ginkgo Biloba Extract, Rhizoma Gastrodiae extraction
80 parts of thing, 60 parts of Fructus Alpinae Oxyphyllae extract, 80 parts of Fructus Schisandrae Chinensis extrat, then add 40 parts of 20 parts of appropriate amount of starch and Microcrystalline Cellulose,
Mixing makes uniform for 10 minutes.
Step 2：Granulation
With 70% ethanol soft material, the granulation of 16 mesh sieves, 55-60 DEG C of drying, 14 mesh sieve granulate.
Step 3：Tabletting
Tabletting, piece weight 0.6g/ pieces, controls ambient temperature 18-25 DEG C, relative humidity 45%-60%.
Step 4：Coating
Bag uniform compact film-coat, controls ambient temperature 18-25 DEG C, relative humidity 45%-60%.
Embodiment 5
Step one：Dispensing
Take 80 parts of 160 parts of phosphatidyl serine, 30 parts of theanine and Radix Ginseng Rubra extract, 50 parts of Ginkgo Biloba Extract, Rhizoma Gastrodiae extraction
80 parts of thing, 60 parts of Fructus Alpinae Oxyphyllae extract, 60 parts of Fructus Schisandrae Chinensis extrat, then add 45 parts of 35 parts of appropriate amount of starch and Microcrystalline Cellulose,
Mixing makes uniform for 25 minutes
Step 2：Granulation
With 75% ethanol soft material, the granulation of 16 mesh sieves, 55-60 DEG C of drying, 14 mesh sieve granulate.
Step 3：Tabletting
Tabletting, piece weight 0.6g/ pieces, controls ambient temperature 18-25 DEG C, relative humidity 45%-60%.
Step 4：Coating
Bag uniform compact film-coat, controls ambient temperature 18-25 DEG C, relative humidity 45%-60%.
Claims (10)
1. one kind improves memory health food, it is characterised in that phosphatidyl serine and tea are included in the raw material of the food
Propylhomoserin.
2. one kind according to claim 1 improves memory health food, it is characterised in that in the raw material of the food also
Include Radix Ginseng Rubra extract, Rhizoma Gastrodiae extract, Fructus Alpinae Oxyphyllae extract, Ginkgo Biloba Extract.
3. one kind according to claim 2 improves memory health food, it is characterised in that in the raw material of the food also
Include food additive Microcrystalline Cellulose and starch.
4. one kind according to claim 2 improves memory health food, it is characterised in that the raw material in the food is matched somebody with somebody
Than for：
Phosphatidyl serine 60-180 weight portions
Radix Ginseng Rubra extract 50-140 weight portions
Theanine 10-100 weight portions
Rhizoma Gastrodiae extract 10-100 weight portions
Ginkgo Biloba Extract 10-100 weight portion
Fructus Alpinae Oxyphyllae extract 10-100 weight portions
Fructus Schisandrae Chinensis extrat 10-100 weight portions.
5. one kind according to claim 2 improves memory health food, it is characterised in that the raw material in the food is matched somebody with somebody
Than for：
Phosphatidyl serine 80-160 weight portions
Radix Ginseng Rubra extract 60-120 weight portions
Theanine 30-90 weight portions
Rhizoma Gastrodiae extract 30-90 weight portions
Ginkgo Biloba Extract 30-90 weight portion
Fructus Alpinae Oxyphyllae extract 30-90 weight portions
Fructus Schisandrae Chinensis extrat 30-90 weight portions.
6. one kind according to claim 2 improves memory health food, it is characterised in that the raw material in the food is matched somebody with somebody
Than for：
Phosphatidyl serine 100-140 weight portions
Radix Ginseng Rubra extract 80-100 weight portions
Theanine 40-80 weight portions
Rhizoma Gastrodiae extract 40-80 weight portions
Ginkgo Biloba Extract 40-80 part
Fructus Alpinae Oxyphyllae extract 40-80 weight portions
Fructus Schisandrae Chinensis extrat 40-80 weight portions.
7. one kind according to claim 2 improves memory health food, it is characterised in that the raw material in the food is matched somebody with somebody
Than for：
120 weight portion of phosphatidyl serine
90 weight portion of Radix Ginseng Rubra extract
60 weight portion of theanine
60 weight portion of Rhizoma Gastrodiae extract
60 weight portion of Ginkgo Biloba Extract
60 weight portion of Fructus Alpinae Oxyphyllae extract
60 weight portion of Fructus Schisandrae Chinensis extrat.
8. the one kind according to any one of claim 1-7 improves memory health food, it is characterised in that the food
The content of the raw material Phosphatidylserine in product must not be less than 10%.
9. the one kind according to any one of claim 1-7 improves memory health food, it is characterised in that the food
Product are tablet form.
10. a kind of a kind of preparation method for improving memory health food as claimed in claim 3, comprises the steps：
1. dispensing：Take phosphatidyl serine 60-180 weight portions, Radix Ginseng Rubra extract 50-140 weight portions, theanine 10-100 weight
Part, Rhizoma Gastrodiae extract 10-100 weight portions,
Ginkgo Biloba Extract 10-100 weight portion, Fructus Alpinae Oxyphyllae extract 10-100 weight portions, Fructus Schisandrae Chinensis extrat 10-100 weight
Part, then add starch 1-80 weight portions and Microcrystalline Cellulose 20-100 weight portion, mixing 10-30 minutes make which uniform；
2. pelletize：With 70-90% ethanol soft materials, the granulation of 16 mesh sieves, 55-60 DEG C of drying, 14 mesh sieve granulate；
3. tabletting：Piece weight 0.6g/ pieces, control ambient temperature 18-25 DEG C, relative humidity 45%-60%；
4. coating：Bag uniform compact film-coat, controls ambient temperature 18-25 DEG C, relative humidity 45%-60%.
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| CN107343892A (en) * | 2017-06-14 | 2017-11-14 | 芜湖福民生物药业股份有限公司 | Traditional Chinese medicine oral liquid and preparation method thereof |
| CN108094990A (en) * | 2017-12-12 | 2018-06-01 | 北京康比特体育科技股份有限公司 | It is a kind of to improve mental energy jelly |
| CN108185427A (en) * | 2018-02-11 | 2018-06-22 | 成都图径生物科技有限公司 | Composition for relieving asthenopia containing flake, theanine and phosphatidylserine |
| CN108651996A (en) * | 2018-03-26 | 2018-10-16 | 广东康侨药业有限公司 | A kind of brain tonic and intelligence development alimentation composition and its application |
| CN116584655A (en) * | 2023-05-22 | 2023-08-15 | 陕西中科通大生命科学技术有限公司 | A nutritional composition for improving brain intelligence, and its preparation method |
| CN118121640A (en) * | 2024-02-05 | 2024-06-04 | 联合理论有限公司 | Composition and soft capsule for treating attention deficit hyperactivity disorder of children as well as preparation method and application of composition and soft capsule |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107343892A (en) * | 2017-06-14 | 2017-11-14 | 芜湖福民生物药业股份有限公司 | Traditional Chinese medicine oral liquid and preparation method thereof |
| CN108094990A (en) * | 2017-12-12 | 2018-06-01 | 北京康比特体育科技股份有限公司 | It is a kind of to improve mental energy jelly |
| CN108185427A (en) * | 2018-02-11 | 2018-06-22 | 成都图径生物科技有限公司 | Composition for relieving asthenopia containing flake, theanine and phosphatidylserine |
| CN108651996A (en) * | 2018-03-26 | 2018-10-16 | 广东康侨药业有限公司 | A kind of brain tonic and intelligence development alimentation composition and its application |
| CN116584655A (en) * | 2023-05-22 | 2023-08-15 | 陕西中科通大生命科学技术有限公司 | A nutritional composition for improving brain intelligence, and its preparation method |
| CN118121640A (en) * | 2024-02-05 | 2024-06-04 | 联合理论有限公司 | Composition and soft capsule for treating attention deficit hyperactivity disorder of children as well as preparation method and application of composition and soft capsule |
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