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CN106525555B - Pretreatment device for detection of irradiated aquatic product derivatives - Google Patents

Pretreatment device for detection of irradiated aquatic product derivatives Download PDF

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Publication number
CN106525555B
CN106525555B CN201610854446.XA CN201610854446A CN106525555B CN 106525555 B CN106525555 B CN 106525555B CN 201610854446 A CN201610854446 A CN 201610854446A CN 106525555 B CN106525555 B CN 106525555B
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China
Prior art keywords
seal case
cylinder
aquatic products
analyte detection
pretreatment unit
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CN201610854446.XA
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CN106525555A (en
Inventor
相兴伟
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Zhejiang Marine Development Research Institute
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Zhejiang Marine Development Research Institute
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Priority to CN201610854446.XA priority Critical patent/CN106525555B/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/4077Concentrating samples by other techniques involving separation of suspended solids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/4077Concentrating samples by other techniques involving separation of suspended solids
    • G01N2001/4088Concentrating samples by other techniques involving separation of suspended solids filtration

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention discloses a kind of derivative analyte detection pretreatment units of irradiation aquatic products, be intended to provide it is a kind of can effectively solve in vacuum because of the poor sealing between cartridge filter and seal case, and the ambient atmos occurred enter in the airtight cavity vacuumized, the pretreatment unit for the problem of causing the intracorporal negative pressure of closed chamber insufficient, influencing the filtration treatment of sample extracting solution.It includes the seal case with sealed internal chamber, the negative-pressure ward mouth being arranged on seal case lateral surface, the placement body for being arranged in outside seal case on top surface and being tightly connected with seal case, is plugged in the intracorporal cartridge filter of housing sleeve and is arranged in the intracorporal adaptive preload sealing mechanism of seal box.

Description

Irradiate the derivative analyte detection pretreatment unit of aquatic products
Technical field
The present invention relates to irradiation aquatic products derivative detection fields, and in particular to a kind of derivative analyte detection use of irradiation aquatic products Pretreatment unit.
Background technique
It is directed to increasingly serious irradiation Safety of Aquatic Products problem at present, gradually carries out the derivative analyte detection skill of irradiation aquatic products Art research studies to the comprehensive of aquatic products quality and systematically the monitoring and irradiation of irradiation aquatic products, promotes aquatic products peace Full control, to guarantee the quality safety of aquatic products.In the derivative analyte detection of irradiation aquatic products, after the sample pre-treatments of aquatic products Resulting sample extracting solution needs are filtered processing, and the liquid after filtration treatment just can be carried out instrument analysis.
Negative pressure filtration mode is the aquatic products sample extracting solution pretreatment in current irradiation aquatic products derivative detection process A kind of mode used when filtering.Current this kind of negative pressure filtration device generally includes aspiration pump, closed case and cartridge filter, and The placement through-hole communicated with the inner cavity of closed case is set on the top surface of closed case, and what cartridge filter can be taken off is plugged in placement In through-hole, and the bottom surface of cartridge filter is equipped with filter membrane interlayer.Sample extracting solution is injected in cartridge filter in practical work process, And vacuumized by inner cavity of the aspiration pump to seal case, so that the sample extracting solution in cartridge filter is made to penetrate filter membrane, Obtain fluid sample to be checked.This kind of negative pressure filtration device during vacuumizing, in order to avoid place through-hole and cartridge filter it Between generate gas leakage, it is common practice to sealing ring directly is set between through-hole and cartridge filter placing;But this sealing means Sealing effect is often bad, in the vacuum of seal case inner cavity, as the negative pressure of seal case inner cavity increases, often holds Leakage problem easily is generated between placement through-hole and cartridge filter, causes ambient atmos to enter seal case inner cavity, influences sample and mention Take the filtration treatment of liquid.On the other hand, in actual use, since cartridge filter needs often to take out cleaning and dress sample, make The sealing ring between through-hole and cartridge filter must be placed to be easy to loosen, generate gap, this also results in extraneous in vacuum The problem of gas enters seal case inner cavity, influences the filtration treatment of sample extracting solution.
Summary of the invention
It can effectively solve vacuumizing the purpose of the present invention is to overcome the shortcomings in the prior art and to provide one kind In the process because of the poor sealing between cartridge filter and seal case, and the ambient atmos occurred enter the airtight cavity vacuumized It is interior, the irradiation aquatic products derivative for the problem of causing the intracorporal negative pressure of closed chamber insufficient, influencing the filtration treatment of sample extracting solution Pretreatment unit is used in detection.
The technical scheme is that
A kind of derivative analyte detection pretreatment unit of irradiation aquatic products includes that the seal case with sealed internal chamber, setting exist Negative-pressure ward mouth on seal case lateral surface, the placement for being arranged in outside seal case on top surface and being tightly connected with seal case Body is plugged in the intracorporal cartridge filter of housing sleeve and is arranged in the intracorporal adaptive preload sealing mechanism of seal box, the sealing The medial surface of the sealed internal chamber of cabinet is equipped with the first interface communicated with seal case lateral surface, the axis for placing body It is vertically arranged, places the upper and lower ends opening of body, place the conical sleeve that the lower part of body is gradually reduced from top to bottom for internal diameter, The lower ending opening for placing body is communicated with the sealed internal chamber of seal case, and the medial surface of the conical sleeve is equipped with the first sealing Circle;The cartridge filter successively includes upper cylinder, middle tapered sleeve and lower cylinder from top to bottom, and the internal diameter of the upper cylinder is greater than lower cylinder Internal diameter, the internal diameter of middle tapered sleeve is gradually reduced from top to bottom, and the lateral surface of the upper cylinder is equipped with the second sealing ring, under described It is successively arranged filter membrane interlayer, first partition and second partition in cylinder from top to bottom, on the lower cylinder and is located at filter membrane The pick-and-place mouth through the inside and outside side of lower cylinder is equipped between interlayer and first partition;The adaptive preload sealing mechanism includes Vertical cylinder body on the inner bottom surface of seal case, setting are set in the intracorporal piston body of vertical cylinder and piston rod, and piston rod Upper end be located at the top of vertical cylinder body, on the vertical cylinder body medial surface and be located above piston body and be equipped with upper limit position block, erect The lateral surface of straight-cylinder body is equipped with the second interface being connected to vertical cylinder body and balance through-hole, and second interface is located at upper limit position block Top, balance through-hole are located at below piston body, are tightly connected between the second interface and first interface by first pipe, institute It states and is equipped with reset spring between piston body and vertical cylinder body inner bottom surface,
The upper end of the piston rod is equipped with the connecting rod radially extended, and the second partition is equipped with piston rod and crosses mouth, living Stopper rod crosses the surface that mouth is located at piston rod, and the edge that piston rod crosses mouth is equipped with connecting rod corresponding with connecting rod and crosses mouth.
Cartridge filter can not only be taken out dress sample or clear by the derivative analyte detection pretreatment unit of the irradiation aquatic products of this programme Wash, and can effectively solve in vacuum because of the poor sealing between cartridge filter and seal case, and the external world occurred Gas enters in the airtight cavity vacuumized, causes the intracorporal negative pressure of closed chamber insufficient, influences the filtration treatment of sample extracting solution The problem of.
Preferably, further including vaccum-pumping equipment, sealed between vaccum-pumping equipment and negative-pressure ward mouth by second pipe Connection.
Preferably, be additionally provided with conical hopper in lower cylinder, conical hopper between filter membrane interlayer and first partition, The medial surface of the top edge of conical hopper and lower cylinder is tightly connected, the pick-and-places mouth be located at conical hopper and first partition it Between.
Preferably, being additionally provided with the filtrate storage container of upper end opening, the upper end of filtrate storage container in first partition Opening.
Preferably, on vertical cylinder body medial surface and being located at below piston body equipped with lower position block, the balance through-hole position In the lower section of lower position block.
Preferably, seal case lateral surface is equipped with the third interface being connected with the sealed internal chamber of seal case, and Third interface is equipped with controlled valve.
Preferably, second partition is located at the lower end of lower cylinder.
Preferably, filter membrane interlayer is close to the upper end of lower cylinder.
Preferably, the taper of the medial surface of conical sleeve is identical as the taper of the lateral surface of middle tapered sleeve.
Preferably, the upper end opening for placing body is located at the top of the outer top surface of seal case, the lower end of body is placed Opening is located at the lower section of the outer top surface of seal case, and the top surface of the lateral surface and seal case of placing body is tightly connected.
The beneficial effects of the present invention are: not only cartridge filter can be taken out dress sample or cleaning, but also can effectively solve taking out Because of the poor sealing between cartridge filter and seal case in vacuum process, and the ambient atmos occurred enter the closed chamber vacuumized In vivo, the problem of causing the intracorporal negative pressure of closed chamber insufficient, influencing the filtration treatment of sample extracting solution.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram of the derivative analyte detection pretreatment unit of irradiation aquatic products of the invention.
Fig. 2 is the schematic diagram of the section structure in Fig. 1 at A-A.
In figure: seal case 1, third interface 11, controlled valve 12, negative-pressure ward mouth 13, first interface 14, first pipe 15, place body 2, conical sleeve 21, the first sealing ring 22, cartridge filter 3, upper cylinder 31, the second sealing ring 32, middle tapered sleeve 33, mistake Filter membrane interlayer 34, lower cylinder 35, conical hopper 36, pick and place mouth 37, first partition 38, second partition 39, piston rod cross mouth 310, Connecting rod crosses mouth 311, and filtrate storage container 4 is adaptive to pre-tighten sealing mechanism 5, vertical cylinder body 51, piston rod 52, upper limit position block 53, piston body 54, reset spring 55, lower position block 56, balance through-hole 57, connecting rod 58, second interface 59.
Specific embodiment
Present invention is further described in detail with specific embodiment with reference to the accompanying drawing:
As shown in Figure 1, a kind of derivative analyte detection pretreatment unit of irradiation aquatic products includes vaccum-pumping equipment, with closed The seal case 1 of inner cavity, is arranged outside seal case on top surface simultaneously the negative-pressure ward mouth 13 being arranged on seal case lateral surface With seal case be tightly connected placement body 2, be plugged in the intracorporal cartridge filter 3 of housing sleeve and setting seal box it is intracorporal from It adapts to pre-tighten sealing mechanism 5.The vaccum-pumping equipment of the present embodiment is aspiration pump.Pass through between vaccum-pumping equipment and negative-pressure ward mouth Second pipe is tightly connected.
The medial surface of the sealed internal chamber of seal case is equipped with the first interface 14 communicated with seal case lateral surface.Sealing Cabinet lateral surface is equipped with the third interface 11 being connected with the sealed internal chamber of seal case, and third interface is equipped with switch valve Door 12.The controlled valve of the present embodiment is manual switch valve or electromagnetic switch valve.
Place the axis vertical setting of body.Place the upper and lower ends opening of body.The upper end opening for placing body is located at The top of the outer top surface of seal case.The lower ending opening of placement body is located at the lower section of the outer top surface of seal case.Place body Lateral surface and seal case top surface be tightly connected.Place the conical sleeve that the lower part of body is gradually reduced from top to bottom for internal diameter 21.The lower ending opening for placing body is communicated with the sealed internal chamber of seal case.The medial surface of conical sleeve is equipped with the first sealing ring 22.The medial surface of conical sleeve is equipped with annular mounting groove, and the first sealing ring is arranged in interior annular mounting groove.
Cartridge filter successively includes upper cylinder 31, middle tapered sleeve 33 and lower cylinder 35 from top to bottom.The outer diameter of upper cylinder, which is less than, to be put Set the internal diameter of body.The internal diameter of upper cylinder is greater than the internal diameter of lower cylinder.The internal diameter of middle tapered sleeve is gradually reduced from top to bottom.Conical sleeve Medial surface taper it is identical as the taper of the lateral surface of middle tapered sleeve.The lateral surface of upper cylinder is equipped with the second sealing ring 32.The Two sealing rings are located at upper cylinder and place between body.First sealing ring is between conical sleeve and middle tapered sleeve.
Filter membrane interlayer 34, first partition 38 and second partition 39 are successively arranged in lower cylinder from top to bottom.Second partition Positioned at the lower end of lower cylinder.Filter membrane interlayer is close to the upper end of lower cylinder.Conical hopper 36, conical hopper are additionally provided in lower cylinder Between filter membrane interlayer and first partition.The medial surface of the top edge of conical hopper and lower cylinder is tightly connected.Lower cylinder The pick-and-place mouth 37 being equipped between filter membrane interlayer and first partition through the inside and outside side of lower cylinder is gone up and is located at, the present embodiment Mouth is picked and placed between conical hopper and first partition.The filtrate storage container 4 of upper end opening is additionally provided in first partition.Filter The upper end opening of liquid storage container.Filtrate storage container can be introduced/taken out by pick-and-place mouth.
The adaptive sealing mechanism that pre-tightens includes the vertical cylinder body 51 being arranged on the inner bottom surface of seal case, is arranged vertical The intracorporal piston body 54 of cylinder and piston rod 52, and the upper end of piston rod is located at the top of vertical cylinder body.The lower end of piston rod and work Cock body is connected.Piston rod is vertically arranged.On vertical cylinder body medial surface and it is located above piston body equipped with upper limit position block 53.Vertically On cylinder body medial surface and it is located at below piston body equipped with lower position block 56.The lateral surface of vertical cylinder body is equipped with to be connected with vertical cylinder body Logical second interface 59 and balance through-hole 57.Second interface is located above upper limit position block.Lead between second interface and first interface The sealed connection of first pipe 15 is crossed, first pipe is located in seal case.Balance through-hole is located at below piston body, the present embodiment Balance through-hole is located at the lower section of lower position block.Reset spring 55 is equipped between piston body and vertical cylinder body inner bottom surface.
As shown in Figure 1 and Figure 2, the upper end of piston rod is equipped with the connecting rod 58 radially extended.Second partition is equipped with piston rod Cross mouth 310.It is circular hole that piston rod, which crosses mouth, and the internal diameter that piston rod crosses mouth is greater than the outer diameter of piston rod.Piston rod crosses mouth and is located at piston The surface of bar.The edge that piston rod crosses mouth is equipped with connecting rod corresponding with connecting rod and crosses mouth 311.
The irradiation aquatic products of the present embodiment derive the specifically used as follows of analyte detection pretreatment unit:
First, cartridge filter is inserted into and places body, and so that connecting rod is passed through corresponding connecting rod and crosses mouth, is located at connecting rod The top of second partition;Then, cartridge filter is rotated by 90 °, so that connecting rod is crossed mouth with connecting rod and be staggered, as shown in Figure 2.
Second, sample extracting solution to be filtered is placed in cartridge filter, and controlled valve is closed.
Third is opened vaccum-pumping equipment and is vacuumized to the sealed internal chamber of seal case;
During vacuumizing: due to the vertical inner chamber of cylinder block above piston body by first interface, first pipe and Second interface is connected to outside air, and the vertical inner chamber of cylinder block below piston body by balance through-hole and seal case it is close Inner cavity connection is closed, thus the air pressure of the vertical inner chamber of cylinder block in vacuum below piston body reduces, and drives piston body Piston rod moves down, and by connecting rod by the past drop-down of entire cartridge filter, so that the lateral surface of middle tapered sleeve be made to be pressed on the first sealing On circle, and as the negative pressure of the sealed internal chamber of seal case increases, the pressure that middle tapered sleeve is pressed on the first sealing ring is also got over Greatly, and then in guaranteeing reliable sealed connection is formed between tapered sleeve and conical sleeve, guarantee to place close between body and cartridge filter Envelope connection, can effectively solve in vacuum because of the poor sealing between cartridge filter and seal case, and the external world occurred Gas enters in the airtight cavity vacuumized, causes the intracorporal negative pressure of closed chamber insufficient, influences the filtration treatment of sample extracting solution The problem of.
Meanwhile during vacuumizing, the sample extracting solution to be filtered in cartridge filter penetrates filter membrane interlayer, cocurrent Enter in filtrate storage container.
4th, after the completion of the sample extracting solution filtering to be filtered in cylinder to be filtered, vaccum-pumping equipment is closed, and opens Controlled valve, so that piston body be made to move up reset under the action of reset spring;Then, cartridge filter is rotated by 90 °, makes to connect Bar and connecting rod cross mouth to just;Followed by cartridge filter can above being mentioned, thus filtrate storage container one by cartridge filter and thereon With by being removed on placement body.

Claims (10)

1. a kind of derivative analyte detection pretreatment unit of irradiation aquatic products, characterized in that including the seal box with sealed internal chamber Body, the negative-pressure ward mouth being arranged on seal case lateral surface are arranged outside seal case on top surface and seal with seal case The placement body of connection is plugged in the intracorporal cartridge filter of housing sleeve and is arranged in the intracorporal adaptive preload sealer of seal box Structure, the medial surface of the sealed internal chamber of the seal case are equipped with the first interface communicated with seal case lateral surface,
The axis vertical setting for placing body, places the upper and lower ends opening of body, place body lower part be it is interior without leave The conical sleeve being gradually reduced under above, the lower ending opening for placing body are communicated with the sealed internal chamber of seal case, the conical sleeve Medial surface be equipped with the first sealing ring;
The cartridge filter successively includes upper cylinder, middle tapered sleeve and lower cylinder from top to bottom, and the internal diameter of the upper cylinder is greater than lower circle The internal diameter of cylinder, the internal diameter of middle tapered sleeve are gradually reduced from top to bottom, and the lateral surface of the upper cylinder is equipped with the second sealing ring, described It is successively arranged filter membrane interlayer, first partition and second partition in lower cylinder from top to bottom, on the lower cylinder and is located at filtering The pick-and-place mouth through the inside and outside side of lower cylinder is equipped between film interlayer and first partition;
The adaptive preload sealing mechanism includes the vertical cylinder body being arranged on the inner bottom surface of seal case, is arranged in vertical cylinder Intracorporal piston body and piston rod, and the upper end of piston rod is located at the top of vertical cylinder body, on the vertical cylinder body medial surface simultaneously Upper limit position block is equipped with above piston body, the lateral surface of vertical cylinder body is equipped with the second interface being connected to vertical cylinder body and puts down Weigh through-hole, and second interface is located above upper limit position block, and balance through-hole is located at below piston body, and the second interface connects with first It is tightly connected between mouthful by first pipe, reset spring is equipped between the piston body and vertical cylinder body inner bottom surface,
The upper end of the piston rod is equipped with the connecting rod radially extended, and the second partition is equipped with piston rod and crosses mouth, piston rod The surface that mouth is located at piston rod is crossed, the edge that piston rod crosses mouth is equipped with connecting rod corresponding with connecting rod and crosses mouth.
2. the derivative analyte detection pretreatment unit of irradiation aquatic products according to claim 1, characterized in that further include taking out very Null device is tightly connected between vaccum-pumping equipment and negative-pressure ward mouth by second pipe.
3. the derivative analyte detection pretreatment unit of irradiation aquatic products according to claim 1, characterized in that the lower cylinder It is inside additionally provided with conical hopper, conical hopper is between filter membrane interlayer and first partition, the top edge of conical hopper and lower circle The medial surface of cylinder is tightly connected, and the pick-and-place mouth is between conical hopper and first partition.
4. the derivative analyte detection pretreatment unit of irradiation aquatic products according to claim 1, characterized in that described first every The filtrate storage container of upper end opening, the upper end opening of filtrate storage container are additionally provided on plate.
5. the derivative analyte detection pretreatment unit of irradiation aquatic products according to claim 1, characterized in that the vertical cylinder On internal side and it is located at below piston body equipped with lower position block, the balance through-hole is located at the lower section of lower position block.
6. the derivative analyte detection pretreatment unit of irradiation aquatic products according to claim 1, characterized in that the seal box Outside is equipped with the third interface being connected with the sealed internal chamber of seal case, and third interface is equipped with controlled valve.
7. the derivative analyte detection pretreatment unit of irradiation aquatic products according to claim 1, characterized in that described second every Plate is located at the lower end of lower cylinder.
8. the derivative analyte detection pretreatment unit of irradiation aquatic products according to claim 1, characterized in that the filter membrane Interlayer is close to the upper end of lower cylinder.
9. the derivative analyte detection pretreatment unit of irradiation aquatic products according to claim 1, characterized in that the conical sleeve Medial surface taper it is identical as the taper of the lateral surface of middle tapered sleeve.
10. the derivative analyte detection pretreatment unit of irradiation aquatic products according to claim 1, characterized in that the placement The upper end opening of body is located at the top of the outer top surface of seal case, and the lower ending opening for placing body is located at the outer top of seal case The top surface of the lower section in face, the lateral surface and seal case of placing body is tightly connected.
CN201610854446.XA 2016-09-27 2016-09-27 Pretreatment device for detection of irradiated aquatic product derivatives Active CN106525555B (en)

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Application Number Priority Date Filing Date Title
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CN106525555B true CN106525555B (en) 2019-01-25

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115762309A (en) * 2022-11-21 2023-03-07 李琳琳 A chemical solubility demonstration test device and test method

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CN105107247A (en) * 2015-07-17 2015-12-02 浙江省海洋水产研究所 Suction type aquaculture tail water particle scavenging equipment
CN105158048A (en) * 2015-08-18 2015-12-16 浙江省海洋水产研究所 Suction type solid-liquid separator
CN105148577A (en) * 2015-07-01 2015-12-16 浙江省海洋水产研究所 Negative pressure suction type filter for aquatic product detection
CN204944924U (en) * 2015-09-06 2016-01-06 中国人民解放军63653部队 The continuous enrichment and separation device of colloid in a kind of Rotary Water
CN105372095A (en) * 2015-12-11 2016-03-02 国家深海基地管理中心 Deep-sea organism suction-type multistage concentration sampling device

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CN105148577A (en) * 2015-07-01 2015-12-16 浙江省海洋水产研究所 Negative pressure suction type filter for aquatic product detection
CN105107247A (en) * 2015-07-17 2015-12-02 浙江省海洋水产研究所 Suction type aquaculture tail water particle scavenging equipment
CN105158048A (en) * 2015-08-18 2015-12-16 浙江省海洋水产研究所 Suction type solid-liquid separator
CN204944924U (en) * 2015-09-06 2016-01-06 中国人民解放军63653部队 The continuous enrichment and separation device of colloid in a kind of Rotary Water
CN105372095A (en) * 2015-12-11 2016-03-02 国家深海基地管理中心 Deep-sea organism suction-type multistage concentration sampling device

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Denomination of invention: Pre treatment device for detecting derivatives of irradiated aquatic products

Granted publication date: 20190125

Pledgee: Industrial and Commercial Bank of China Limited Zhoushan Branch

Pledgor: ZHEJIANG MARINE DEVELOPMENT Research Institute

Registration number: Y2024330002355