CN106421471A - Traditional Chinese medicine preparation for treating kidney calculi - Google Patents

Abstract

The invention belongs to the technical field of research and development of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation for treating kidney stones. A traditional Chinese medicine preparation for treating kidney stones, which is prepared from the following raw materials in parts by weight: 15-30 parts of Desmodium, 10-20 parts of Haijinsha, 9-16 parts of Atractylodes Rhizome, 15-30 parts of Radix Astragali, and 12 parts of Rhizoma Imperatae ‑17 parts, Polyporus 11‑19 parts, Poria cocos 9‑18 parts, mallow seeds 10‑14 parts, honeysuckle vine 13‑17 parts, red thistle 25‑35 parts, false pineapple 15‑25 parts, chicken gizzard 15‑30 parts, Eucommia 10‑20 parts, Achyranthes bidentata 15‑22 parts and licorice 6‑9 parts. The traditional Chinese medicine preparation for treating kidney stones of the invention has less toxic and side effects, significant curative effect, treats both symptoms and root causes, and has a low recurrence rate after cure; the Chinese medicine preparation for treating kidney stones of the invention has a simple preparation method, low cost, easy operation, and easy popularization and application.

Description

A kind of traditional Chinese medicine preparation for treating kidney stones

technical field

The invention belongs to the technical field of research and development of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation for treating kidney stones and a preparation method thereof.

Background technique

Kidney stones are one of the most common diseases of the urinary system. There are records about the cause of disease, symptoms and treatment of stone disease in the medical literature of the motherland before two thousand years. Along with the raising of people's material living standard, the improvement of nutritional status has aggravated the irrationality of diet allocation, and the raising of high-protein, high-sugar diet composition makes the sickness rate of kidney stone constantly rise. In the past 30 years, the causes of kidney stone formation and specific molecular defects have been clarified, most nephrolithiasis can be specifically diagnosed, and a variety of drugs have been proven to be effective in the treatment of kidney stones.

At present, it is believed that the occurrence of stones is due to the combined action of various factors that increase the concentration of crystal substances in urine or reduce the solubility, and crystals are precipitated in a supersaturated state, grow and accumulate locally, and finally form stones. The individual differences in the formation of kidney stones are relatively large. Clinically, stones are usually divided into four categories: calcium stones, infection stones, uric acid stones, and cystine stones. The treatment of kidney stones has made great progress in recent years. Many patients who needed surgery in the past can now undergo extracorporeal shock wave fragmentation or non-open surgery to remove stones.

However, no matter whether it is surgery to remove stones or physical crushing and removal of stones, it is impossible to radically cure kidney stones. Authoritative data show that the recurrence rate of urinary stones is as high as 96.5%. 87.6% of patients suffer from low back pain or abdominal pain for a long time. 69% of patients are often accompanied by hematuria or pyuria due to organ damage. Urinary stones come one after another, and the stone disease is often repeated, causing the patient to suffer unbearably. Western medicine treatment mainly uses inorganic or/and organic acidic drugs to dissolve stones and expel stones, but its therapeutic effect is very small, and its side effects are relatively large, so it is mostly used as adjuvant therapy. Therefore, need Chinese medicine scientific research personnel to need to develop a kind of prescription exquisite, and the Chinese medicine formula with good therapeutic effect, to reach the purpose of efficient, thorough treatment kidney calculus patient.

The information disclosed in this Background section is only for enhancing the understanding of the general background of the present invention and should not be taken as an acknowledgment or any form of suggestion that the information constitutes the prior art that is already known to those skilled in the art.

Contents of the invention

In order to solve the above problems, the object of the present invention is to provide a Chinese medicine preparation for treating kidney stones and a preparation method thereof.

The technical scheme provided by the present invention is:

A traditional Chinese medicine preparation for treating kidney stones, which is prepared from the following raw materials in parts by weight: 15-30 parts of Desmodium chinensis, 10-20 parts of Haijinsha, 9-16 parts of Atractylodes Rhizome, 15-30 parts of Radix Astragali, and 12 parts of Rhizoma Imperatae -17 parts, Polyporus 11-19 parts, Poria cocos 9-18 parts, mallow seeds 10-14 parts, honeysuckle vine 13-17 parts, red thistle 25-35 parts, fake pineapple 15-25 parts, chicken gizzard 15-30 parts, Eucommia 10-20 parts, Achyranthes bidentata 15-22 parts and licorice 6-9 parts.

As a preference, the traditional Chinese medicine preparation for treating kidney stones is made of the following raw materials in parts by weight: 20 parts of Desmodium, 18 parts of Haijinsha, 15 parts of Atractylodes Rhizome, 16 parts of Radix Astragali, 13 parts of Rhizoma Imperatae, Polyporus 15 parts, Poria cocos 15 parts, mallow seed 13 parts, honeysuckle vine 15 parts, red thistle 27 parts, false pineapple 21 parts, chicken gizzard 22 parts, eucommia ulmoides 16 parts, achyranthes bidentata 19 parts and licorice 7 parts.

The present invention also provides the preparation method of the Chinese medicine preparation for the treatment of kidney stones, comprising the following steps:

(1) Desmodium, seaweed, Atractylodes macrocephala, Astragalus root, Imperatae rhizome, Poria cocos, Poria cocos, mallow seed, honeysuckle vine, red thistle, false pineapple, chicken gizzard, ulmoides, achyranthes bidentata and licorice in parts by weight ;

(2) Mix and wash the raw materials of the above-mentioned Chinese medicines, put them into a decoction casserole or earthen pot, add clean water, add water until the medicine surface is soaked by 3-4cm, soak for 30-40min before decocting, Then, boil it with strong fire, then switch to slow fire decoction, turn off the fire when each dose is decocted to 180-200mL of medicine juice, filter out the medicine residue, take medicine juice, and obtain the traditional Chinese medicine preparation for treating kidney stones.

Compared with the prior art, the present invention has the following beneficial effects:

(1) The traditional Chinese medicine preparation for treating kidney stones of the present invention is simple in formula, easy to take, low in cost, and less in pain for patients. At the same time, effective health care for the patient's kidneys will make the patient's damaged kidneys recover as soon as possible, and the treatment will take effect quickly and the cure rate will be high.

(2) The preparation method of the traditional Chinese medicine preparation for treating kidney stones of the present invention is simple, low in cost, easy to operate, and easy to popularize and apply.

detailed description

The present invention will be described in further detail below in conjunction with specific examples. The Chinese herbal medicine mentioned in the embodiment is prescribed medicinal parts according to the Pharmacopoeia

Embodiment 1 :

A traditional Chinese medicine preparation for treating kidney stones, which is made of the following raw materials in parts by weight: 15g of Desmodium syringae, 10g of Haijinsha, 9g of Atractylodes Rhizoma Atractylodes Rhizome, 15g of Radix Astragali, 12g of Rhizoma Imperatae, 11g of Poria cocos, 9g of Poria cocos, and 10g of mallow seeds , honeysuckle vine 13g, red thistle 25g, fake pineapple 15g, chicken gizzard 15g, Eucommia 10g, achyranthes bidentata 15g and licorice 6g.

The preparation method of the Chinese medicinal preparation for the treatment of kidney stones, comprises the following steps:

(1) Desmodium, seaweed, Atractylodes macrocephala, Astragalus, Imperatae, Polyporus cocos, Poria cocos, mallow seed, honeysuckle vine, red thistle, false pineapple, chicken gizzard, eucommia, achyranthes bidentata and licorice in parts by weight ;

(2) Then mix and wash the raw materials of the above-mentioned Chinese medicines, put them into a decoction casserole or earthen pot, add clean water, add water until the medicine surface is soaked by 3cm, soak for 30 minutes before decocting, and then use strong fire Boil, then switch to slow fire decoction, turn off the heat when each dose is decocted to 180mL of medicine juice, filter off the medicine residue, take the medicine juice, and obtain the traditional Chinese medicine preparation for treating kidney stones.

Embodiment 2 :

A traditional Chinese medicine preparation for treating kidney stones, which is made from the following raw materials in parts by weight: 30g of Desmodium chinensis, 20g of Rhizoma Atractylodes Rhizome, 16g of Atractylodes Rhizoma Atractylodes Rhizome, 30g of Radix Astragali, 17g of Rhizoma Imperatae, 19g of Poria cocos, 18g of Poria cocos, and 14g of mallow seeds , honeysuckle vine 17g, red thistle 35g, fake pineapple 25g, chicken gizzard 30g, eucommia 20g, achyranthes bidentata 22g and licorice 9g.

The preparation method of the Chinese medicinal preparation for the treatment of kidney stones, comprises the following steps:

(1) Desmodium, seaweed, Atractylodes macrocephala, Astragalus root, Imperatae rhizome, Poria cocos, Poria cocos, mallow seed, honeysuckle vine, red thistle, false pineapple, chicken gizzard, ulmoides, achyranthes bidentata and licorice in parts by weight ;

(2) Mix and wash the raw materials of the above-mentioned traditional Chinese medicines, put them into a decoction casserole or earthen pot, add clean water, add water until the surface of the medicine is soaked by 4cm, soak for 40 minutes before decocting, and then use strong fire Boil, then use slow fire to decoct, turn off the heat when each dose is decocted to 200mL of medicinal juice, filter off the medicinal residue, take the medicinal juice, and obtain the traditional Chinese medicine preparation for treating kidney stones.

Embodiment 3 :

A traditional Chinese medicine preparation for treating kidney stones, which is made of the following raw materials in parts by weight: 20g of Desmodium, 15g of Rhizoma Atractylodes Rhizome, 12g of Atractylodes Rhizome, 25g of Radix Astragali, 15g of Rhizome Imperatae, 15g of Poria cocos, 13g of Poria cocos, and 12g of mallow seed , honeysuckle vine 15g, red thistle 30g, fake pineapple 20g, chicken gizzard 20g, eucommia 15g, achyranthes bidentata 18g and licorice 8g.

The preparation method of the Chinese medicinal preparation for the treatment of kidney stones, comprises the following steps:

(1) Desmodium, seaweed, Atractylodes macrocephala, Astragalus root, Imperatae rhizome, Poria cocos, Poria cocos, mallow seed, honeysuckle vine, red thistle, false pineapple, chicken gizzard, ulmoides, achyranthes bidentata and licorice in parts by weight ;

(2) Then mix and wash the above-mentioned Chinese medicine raw materials, put them into a decocting casserole or earthen pot, add clean water, add water until the medicine surface is soaked by 3.5cm, soak for 35 minutes before decocting, and then use force Bring to a boil over high heat, then decoct with slow fire, turn off the heat when each dose is decocted to 190mL of medicine juice, filter out the medicine residue, take the medicine juice, and then obtain the traditional Chinese medicine preparation for treating kidney stones.

Embodiment 4 : the effect test of Chinese medicine preparation of the present invention

(1) General information

Inclusion criteria: Pain and discomfort in the waist and kidney area or lower abdomen, frequent urination, urgency, dysuria, kidney stones diagnosed by renal B-ultrasound, X-ray or contrast imaging; stone diameter less than 10mm; normal renal function; no urinary tract obstruction below the stone . Selected 400 examples altogether, treatment group 300 examples (divided into 3 groups at random, namely treatment group 1, treatment group 2 and treatment group 3), wherein male 150 examples, female 150 examples, age 46-75 years old, average age 60.5 years old, The disease course was 1-5 years; the control group consisted of 100 cases, including 48 males and 52 females, aged 45-74 years, with an average age of 59.5 years, and the disease course was 1-4 years.

(2) Research methods

Treatment group: Treatment groups 1-3 respectively took the traditional Chinese medicine preparation prepared by the method in Example 1-3 of the present invention, 1 dose per day, divided into 3 doses, 1 dose each in the morning, noon and evening, after meals, and delivered with warm boiled water. Take it, drink more than 1500mL of water every day. A course of treatment is 30 days, taking 3 courses of treatment continuously.

Control group: Oral Urostone (Jilin Wantong Pharmaceutical Group), three times a day, 4 grams each time, drinking more than 1500mL of water every day. During the treatment period, the patients in the two groups drank more water and did more jumping exercises. Patients with pain were given anisodamine 5-10 mg intramuscularly or orally, and those with urinary tract infection were given antibiotics. One course of treatment was 30 days, and three courses of treatment were taken continuously.

(3) Judgment criteria for curative effect

Healed: Symptoms and signs disappeared, sand and stones were discharged with the naked eye, B-ultrasound and abdominal plain film examination of kidneys, ureters, and bladder were normal.

Improvement: Symptoms and signs disappeared, and B-ultrasound and abdominal plain film examination showed that the stones moved down or became smaller.

Ineffective: Symptoms, signs and examinations did not improve significantly.

(4) Research results

After 30 days of treatment, the curative effects of the two groups are compared in Table 1.

The effect test of the Chinese medicine preparation of the present invention of table 1

As can be seen from Table 1, the effective rates in Examples 1-3 are all above 90%; while in the control group, 25 cases were cured, 33 cases improved, 42 cases were ineffective, and the effective rate was 58%. In a word, the cure rate and total effective rate of kidney stones prepared by the traditional Chinese medicine preparation prepared by the method in Examples 1-3 of the present invention are significantly higher than those of the control group.

The foregoing descriptions of specific exemplary embodiments of the present invention have been presented for purposes of illustration and description. These descriptions are not intended to limit the invention to the precise form disclosed, and obviously many modifications and variations are possible in light of the above teaching. The exemplary embodiments were chosen and described in order to explain the specific principles of the invention and its practical application, thereby enabling others skilled in the art to make and use various exemplary embodiments of the invention, as well as various Choose and change. It is intended that the scope of the invention be defined by the claims and their equivalents.

Claims (3)

1. A Chinese medicine preparation for the treatment of kidney stones, characterized in that, it is made of the following raw materials in parts by weight: 15-30 parts of Desmodium, 10-20 parts of Haijinsha, 9-16 parts of Atractylodes Rhizome, 15-30 parts of Radix Astragali 30 parts, 12-17 parts of Imperata rhizome, 11-19 parts of Polyporus cocos, 9-18 parts of Poria cocos, 10-14 parts of mallow seed, 13-17 parts of honeysuckle, 25-35 parts of red thistle, 15- 25 parts, chicken gizzard 15-30 parts, Eucommia 10-20 parts, Achyranthes bidentata 15-22 parts and licorice 6-9 parts. 2. The Chinese medicine preparation for the treatment of kidney stones according to claim 1, characterized in that, it is made of the following raw materials in parts by weight: 20 parts of Desmodium, 18 parts of Haijinsha, 15 parts of Atractylodes Rhizome, 16 parts of Radix Astragali, 13 parts of Rhizoma Imperatae, 15 parts of Polyporus cocos, 15 parts of Poria cocos, 13 parts of mallow seed, 15 parts of honeysuckle, 27 parts of red thistle, 21 parts of false pineapple, 22 parts of chicken gizzard, 16 parts of Eucommia, 19 parts of achyranthes bidentata And licorice 7 parts. 3. the preparation method of the Chinese medicine preparation for the treatment of kidney stones according to claim 1 or 2, is characterized in that, comprises the following steps: (1) Desmodium, seaweed, Atractylodes macrocephala, Astragalus root, Imperatae rhizome, Poria cocos, Poria cocos, mallow seed, honeysuckle vine, red thistle, false pineapple, chicken gizzard, ulmoides, achyranthes bidentata and licorice in parts by weight ; (2) Mix and wash the raw materials of the above-mentioned Chinese medicines, put them into a decoction casserole or earthen pot, add clean water, add water until the medicine surface is soaked by 3-4cm, soak for 30-40min before decocting, Then, boil it with strong fire, then switch to slow fire decoction, turn off the fire when each dose is decocted to 180-200mL of medicine juice, filter out the medicine residue, take medicine juice, and obtain the traditional Chinese medicine preparation for treating kidney stones.