CN106389487A - Compound pharmaceutical composition used for poultry and capable of lowering medicine side effect - Google Patents
Compound pharmaceutical composition used for poultry and capable of lowering medicine side effect Download PDFInfo
- Publication number
- CN106389487A CN106389487A CN201611045584.XA CN201611045584A CN106389487A CN 106389487 A CN106389487 A CN 106389487A CN 201611045584 A CN201611045584 A CN 201611045584A CN 106389487 A CN106389487 A CN 106389487A
- Authority
- CN
- China
- Prior art keywords
- pharmaceutical composition
- poultry
- medicine
- side effect
- compound pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 36
- 150000001875 compounds Chemical class 0.000 title claims abstract description 27
- 244000144977 poultry Species 0.000 title claims abstract description 20
- 230000000694 effects Effects 0.000 title abstract description 4
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 6
- 229960004821 amikacin Drugs 0.000 claims abstract description 13
- LKCWBDHBTVXHDL-RMDFUYIESA-N amikacin Chemical compound O([C@@H]1[C@@H](N)C[C@H]([C@@H]([C@H]1O)O[C@@H]1[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O1)O)NC(=O)[C@@H](O)CCN)[C@H]1O[C@H](CN)[C@@H](O)[C@H](O)[C@H]1O LKCWBDHBTVXHDL-RMDFUYIESA-N 0.000 claims abstract description 13
- 239000000203 mixture Substances 0.000 claims description 19
- 206010061623 Adverse drug reaction Diseases 0.000 claims description 15
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 claims description 15
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 5
- 230000008901 benefit Effects 0.000 abstract description 5
- 235000013305 food Nutrition 0.000 abstract description 4
- 240000001638 Scurrula parasitica Species 0.000 abstract 3
- 239000008159 sesame oil Substances 0.000 abstract 3
- 235000011803 sesame oil Nutrition 0.000 abstract 3
- 241000894006 Bacteria Species 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 description 8
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 238000001035 drying Methods 0.000 description 4
- 239000012467 final product Substances 0.000 description 3
- 244000045947 parasite Species 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 206010059866 Drug resistance Diseases 0.000 description 2
- 229940088710 antibiotic agent Drugs 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 239000003640 drug residue Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 210000000582 semen Anatomy 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000002141 anti-parasite Effects 0.000 description 1
- 239000003443 antiviral agent Substances 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 231100000753 hepatic injury Toxicity 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a compound pharmaceutical composition used for poultry and capable of lowering the medicine side effect. The compound pharmaceutical composition comprises, by weight, 50-100 parts of loranthus parasiticus, 0.01-0.03 part of sesame oil and 10-20 parts of amikacin. The compound pharmaceutical composition has the advantages that the traditional Chinese medicine loranthus parasiticus, the sesame oil and the amikacin are combined to form the compound pharmaceutical composition, the antibacterial medicine tolerance of bacteria can be reversed by adding the loranthus parasiticus and the sesame oil into the amikacin which is the antibacterial medicine, and accordingly the curative effect of the antibacterial medicine can be increased; the compound pharmaceutical composition can greatly lower medicine use cost and medicine residues, high economic benefits can be created for farmers, and food safety is guaranteed at the same time.
Description
Technical field
The present invention relates to a kind of compound medicament composition, particularly to a kind of poultry compound medicine reducing drug side effect
Compositionss.
Background technology
In recent years, in livestock breed aquatics practice, even bacterial infection, viral infectious, parasite infectivity disease
Drug induccd hepatic injury class disease is in trend occurred frequently.The generation of these diseases and evolution, use in a large number during adding preventing and treating is each
Class antibacterials, anti-parasite medicine and antiviral drugs, so that antibacterial or parasite medicine resistance ability strengthen, cause poultry to go out
Existing disease cannot be by the problem of common drug treatment.And antibiotics are using excessive, people food poultry when
Wait and also can be affected, therefore, need a kind of medicine that there is disinfection and deinsectization effect and there is relatively low antibiotic composition at present badly.
The information being disclosed in this background section is merely intended to increase the understanding of the general background to the present invention, and should not
Recognize when being considered or imply in any form that this information structure has been the prior art well known to persons skilled in the art.
Content of the invention
The present invention is directed to above-mentioned technical problem, a kind of poultry compound medicament composition reducing drug side effect of invention, purport
Obtaining a kind of pathogenic bacterium that can murder in poultry body, remove parasite there is the compound medicine of relatively low antibiotic composition again
Compositionss.
For achieving the above object, the technical scheme that the present invention provides is as follows：
A kind of poultry compound medicament composition reducing drug side effect, composed of the following components according to ratio of weight and number：
50～100 parts of Herba Taxilli, 0.01～0.03 part of Oleum sesami, 10～20 parts of amikacin.
Wherein, described Herba Taxilli pulverized 100～180 mesh sieve gained after drying 30～50 minutes through 30～50 DEG C.
Wherein, every 1kg feedstuff adds the poultry compound medicament composition of above-mentioned reduction drug side effect in use
0.1～0.2g.
Compared with prior art, the present invention has the advantages that：
The present invention reduces the poultry compound medicament composition of drug side effect, using herb lorathlorace and Semen Sesami, A meter Ka
Star forms compound medicine, and amikacin is antimicrobial drug, being capable of reverse bacterial pair after adding Herba Taxilli and Oleum sesami in antimicrobial drug
The drug resistance of antimicrobial drug, thus improve the therapeutic effect of antimicrobial drug；Further product of the present invention can be greatly reduced drug cost
And drug residue, it is that raiser creates higher economic benefit, also ensure that food safety simultaneously.
Specific embodiment
It is described in detail with reference to specific embodiment, it is to be understood that protection scope of the present invention is not subject to specifically
The restriction of embodiment.
Embodiment 1
A kind of poultry compound medicament composition reducing drug side effect, weighs following components in units of g：Herba Taxilli
500g, Oleum sesami 0.01g, amikacin 10g, then by Herba Taxilli and Oleum sesami mixing and stirring, add grind into powder
In the amikacin of shape, extrude slabbing or graininess, obtain final product；Wherein, Herba Taxilli pulverized 100 after drying 50 minutes through 30 DEG C
Mesh sieve gained.
Every 1kg feedstuff adds 0.1g to the poultry compound medicament composition of above-mentioned reduction drug side effect in use.
Embodiment 2
A kind of poultry compound medicament composition reducing drug side effect, weighs following components in units of g：Herba Taxilli
100g, Oleum sesami 0.03g, amikacin 20g, then by Herba Taxilli and Oleum sesami mixing and stirring, add grind into powder
In the amikacin of shape, extrude slabbing or graininess, obtain final product；Wherein, Herba Taxilli pulverized 180 after drying 30 minutes through 50 DEG C
Mesh sieve gained.
Every 1kg feedstuff adds 0.2g to the poultry compound medicament composition of above-mentioned reduction drug side effect in use.
Embodiment 3
A kind of poultry compound medicament composition reducing drug side effect, weighs following components in units of g：Herba Taxilli
90g, Oleum sesami 0.02g, amikacin 15g, then by Herba Taxilli and Oleum sesami mixing and stirring, addition is ground into powder
Amikacin in, extruding slabbing or graininess, obtain final product；Wherein, Herba Taxilli pulverized 140 mesh after drying 40 minutes through 40 DEG C
Sieve gained.
Every 1kg feedstuff adds 0.1g to the poultry compound medicament composition of above-mentioned reduction drug side effect in use.
The present invention reduces the poultry compound medicament composition of drug side effect, using herb lorathlorace and Semen Sesami, A meter Ka
Star forms compound medicine, and amikacin is antimicrobial drug, being capable of reverse bacterial pair after adding Herba Taxilli and Oleum sesami in antimicrobial drug
The drug resistance of antimicrobial drug, thus improve the therapeutic effect of antimicrobial drug；Further product of the present invention can be greatly reduced drug cost
And drug residue, it is that raiser creates higher economic benefit, also ensure that food safety simultaneously.
The description of the aforementioned specific illustrative embodiment to the present invention illustrate that and illustration purpose.These descriptions
It is not wishing to limit the invention to disclosed precise forms, and it will be apparent that according to above-mentioned teaching, can much be changed
And change.The purpose of selecting and describing the exemplary embodiment is that explaining that the certain principles of the present invention and its reality should
With so that those skilled in the art be capable of and utilize the present invention various different exemplary and
Various different selections and change.The scope of the present invention is intended to be limited by claims and its equivalents.
Claims (3)
1. a kind of poultry compound medicament composition reducing drug side effect is it is characterised in that according to ratio of weight and number by following
Group is grouped into：50～100 parts of Herba Taxilli, 0.01～0.03 part of Oleum sesami, 10～20 parts of amikacin.
2. compound medicament composition according to claim 1 it is characterised in that：Described Herba Taxilli is dried through 30～50 DEG C
100～180 mesh sieve gained were pulverized after 30～50 minutes.
3. compound medicament composition according to claim 1 it is characterised in that：The poultry of described reduction drug side effect
Every 1kg feedstuff adds 0.1～0.2g to compound medicament composition in use.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611045584.XA CN106389487A (en) | 2016-11-24 | 2016-11-24 | Compound pharmaceutical composition used for poultry and capable of lowering medicine side effect |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611045584.XA CN106389487A (en) | 2016-11-24 | 2016-11-24 | Compound pharmaceutical composition used for poultry and capable of lowering medicine side effect |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106389487A true CN106389487A (en) | 2017-02-15 |
Family
ID=58082931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611045584.XA Pending CN106389487A (en) | 2016-11-24 | 2016-11-24 | Compound pharmaceutical composition used for poultry and capable of lowering medicine side effect |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106389487A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103933086A (en) * | 2014-04-25 | 2014-07-23 | 广西大学 | Creat/amikacin-containing compound medicine for livestock and fowl |
| CN103948692A (en) * | 2014-05-14 | 2014-07-30 | 广西南宁市桃源兽药厂 | Red paeonia/amikacin-containing compound medicine for livestock and fowl |
| CN103989725A (en) * | 2014-05-28 | 2014-08-20 | 广西大学 | Acalypha australis L. and amikacin containing compound medicine for livestock and poultry |
-
2016
- 2016-11-24 CN CN201611045584.XA patent/CN106389487A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103933086A (en) * | 2014-04-25 | 2014-07-23 | 广西大学 | Creat/amikacin-containing compound medicine for livestock and fowl |
| CN103948692A (en) * | 2014-05-14 | 2014-07-30 | 广西南宁市桃源兽药厂 | Red paeonia/amikacin-containing compound medicine for livestock and fowl |
| CN103989725A (en) * | 2014-05-28 | 2014-08-20 | 广西大学 | Acalypha australis L. and amikacin containing compound medicine for livestock and poultry |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170215 |