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CN106361892A - Traditional Chinese medicine decoction for treating pediatric epilepsy, and preparation method and application thereof - Google Patents

Traditional Chinese medicine decoction for treating pediatric epilepsy, and preparation method and application thereof Download PDF

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CN106361892A
CN106361892A CN201610949079.1A CN201610949079A CN106361892A CN 106361892 A CN106361892 A CN 106361892A CN 201610949079 A CN201610949079 A CN 201610949079A CN 106361892 A CN106361892 A CN 106361892A
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黄元清
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a traditional Chinese medicine decoction for treating pediatric epilepsy. The traditional Chinese medicine decoction is prepared from the following raw materials in parts by weight: 35-50 parts of dry Chinese wolfberry tree root, 1-5 parts of dry phoenix tree root and 150-250 parts of fresh ecological pig lean meat. The preparation method comprises the following steps: taking the dry Chinese wolfberry tree root and dry phoenix tree root, respectively cleaning and slicing, taking the fresh ecological pig lean meat, cleaning, and slicing or chopping; mixing the three raw materials according to parts by weight, putting the raw material mixture in a ceramic bowl, adding spring water which just immerses the raw material mixture, putting the raw-material-mixture-containing ceramic bowl in a steamer, and steaming at 80-100 DEG C for 2-2.5 hours; and filtering the steamed raw material mixture, thereby obtaining the decoction. The decoction has the advantages of quick effect taking, no toxic or side effect, definite drug effect, favorable curative effect and no relapse, and can reduce the injuries on the brain neural mechanisms. The preparation method has the advantages of wide material sources, low cost and simple preparation process, and thus, has higher popularization value.

Description

A kind of treat Chinese medicine decoction of children epilepsy and its preparation method and application
Technical field
The present invention relates to field of Chinese herbal and in particular to a kind of treat Chinese medicine decoction of children epilepsy and preparation method thereof and Application.
Background technology
Epilepsy is commonly called as " sheep eclampsia " or " sheep wind ", be a kind of children's period common cause of disease complicated, recurrent exerbation Nervous system syndrome.Caused by the temporary functional disorders of brain of paroxysm, clinical manifestation is taken out for the various forms of of repeated relapsing Outbreak of jerking prolonged and repeated outbreak impact intelligent development.Epilepsy can be divided into essential epilepsy and Secondary cases according to the difference of pathogenic factor Epilepsy.Essential epilepsy except suspected genetic tendency in addition to, no other obvious causes of disease.Often in a certain special age bracket onset, there is spy Levying property clinic and EEG.Secondary epilepsy is symptomatic epilepsy again, is various clear and definite or possible central nervous system Caused by pathological changes, such as brain textural anomaly or the various factors affecting brain function, such as chromosomal abnormality, congenital diseases, perinatal stage damage Wound, wound, infection, poisoning, intracranial tumor, cerebrovascular disease, Nutrition and Metabolism disease etc..
Mainly because children's nervous system development is not complete, cerebral cortex is subject to hyperpyrexia or violent direct stimulation, produces excessively Caused by excited.Lure originator the most common with hyperpyrexia.Most children's syncope, with one's eyes tight shut or half-open, eyeball during convulsions On turn over, gnathospasma, bicker twitch, head to layback, extremity bend and stretch repeatedly, simultaneously because breast, abdominal muscle are tetanic, respiratory standstill, therefore entirely Body anoxia, cyanotic lipses, orthotonus, continue to arrive 1-2 minute in more than ten seconds, but also have only a few children's symptom lighter, consciousness Still clear, just like ordinary person after outbreak.
Before two thousand yearses, ancient china is early recognized to epilepticss.In Huangdi's Internal Classics, epilepsy two word was had true The definition cut, " insane " is i.e. demented, represents disturbance of consciousness during outbreak;" epilepsy " twitches, and represents spasticity during outbreak.The traditional Chinese medical science , epilepsy, in stage of attack, first has to symptomatic treatment in acute condition to treatment epilepsy origin, controls its outbreak, releases patient as early as possible and faints and take out The state of necessity jerked, preferably to eliminate phlegm for resuscitation, relieving spasm by subduing liver-wind as method for the treatment of, it is fast and act on strong, using different treatments that curative effect is controlled in choosing Approach.In resting stage or catabasises, the state of an illness tends to relaxing, now then with the principle of radical treatment in chronic case, conscientiously meticulously dialectical, recognizes Clear its sick position, characteristic of disease, are controlled it, respectively on the whole with invigorating the spleen for dissipating phlegm, nourishing liver and kidney and tranquilizing mind by nourishing heart as method for the treatment of, except its expectorant, wind Source, with Zhi Qiben, prevent this palindromia.Determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs is showed according to Comprehensive Clinical, domination of pathogen person, to attack based on heresy simultaneously; The person that has virtual image, gives righting.Attack evil conventional relieve dizziness, high fever, infantile convulsions, epilepsy, etc., pathogenic fire purging, promoting blood circulation, the method such as clearing away phlegm, the multiplex liver nourishing of righting, spleen invigorating, nourishing heart, tonification Etc. method.But there is the domination of pathogen and weakened body resistance, while attacking heresy, righting to be taken into account, have exopathogen while weakened body resistance concurrently, then with righting be Main, and with eliminating evil, reach eliminating evil and equal insane final purpose.
At present, though western medicine and medical practitioners have its advantage in terms of controlling epilepsy, too strong inhibitory action can be to cerebral nerve Function damages, and has obvious toxic-side effects, is also easy to produce drug dependence, is easily caused the secondary work such as spirit depressing, dysnoesia With being therefore difficult to be accepted by patients.In addition, informal dress epilepsy Western medicine, it is easily caused medicine and adapts to, want to keep certain treatment Effect must increasing dosage, formed vicious cycle.
Content of the invention
It is an object of the invention to provide a kind of rapid-action, drug effect is definite, one kind of having no toxic side effect treats children epilepsy Chinese medicine decoction and its preparation method and application, to solve the problems, such as to provide in above-mentioned background technology.
For achieving the above object, the following technical scheme of present invention offer:
A kind of Chinese medicine decoction treating children epilepsy, is made up of the following raw material according to weight portion: dry wolfberry tree root 35-50 part, Dry Phoenix tree root 1-5 part, fresh ecology pig lean meat 150-250 part.
As the further scheme of the present invention: a kind of described Chinese medicine decoction treating children epilepsy, by following according to weight The raw material composition of part: dry wolfberry tree root 40-45 part, dry Phoenix tree root 1-3 part, fresh ecology pig lean meat 180-220 part.
As the further scheme of the present invention: a kind of described Chinese medicine decoction treating children epilepsy, by following according to weight The raw material composition of part: 43 parts of dry wolfberry tree root, 2 parts of dry Phoenix tree root, fresh 200 parts of pig lean meat of ecology.
A kind of preparation method of described Chinese medicine decoction treating children epilepsy, comprises the steps of:
1) take dry wolfberry tree root and dry Phoenix tree root, cut into pieces after cleaning respectively, then take fresh ecology pig lean meat, clean section Or chopping;
2) press respective weight portion and prepare dry wolfberry tree root, dry Phoenix tree root and the three kinds of raw material mixing of fresh ecology pig lean meat, will Mixed material is placed in ceramic bowl, adds the spring water of just submergence mixed material, then the ceramic bowl filling mixed material is put into Steam in pot, place 2-2.5 hour at 80-100 DEG C;
3) mixed material filters after steaming, and obtains final product decoction.
A kind of described Chinese medicine decoction treating children epilepsy treats the application in children epilepsy medicine in preparation.
The property of medicine pharmacology of medicine selected by the present invention is:
Boxthorn root: be also called " Cortex Lycii ", clearind deficient heat Chinese medicine, " book on Chinese herbal medicine is stated ": cure mainly deficient fever, alternate attacks of chills and fever, all see blood disorder, Epistaxis, cough blood, cough, breathe heavily, diseases due to endogenous heat of ZANG FU organs, apoplexy, dizziness, convulsion epilepsy, lumbago, migratory arthralgia, tinea pedis, edema, and fidgets due to deficiency is throbbed with fear, forgetful, urine Obstructed, reddish and whitish turbid urine.
Modern pharmacological research: Cortex Lycii contains the derivant of guanidine, has hypoglycemic activity." Chinese medicine information " is reported: ground Cortex Lycii has reduction to act on to mouse glucose and adrenal gland's disposition hyperglycemia, and diabetic rat model beta Cell of islet form is tied The infringement of structure has certain mitigation to act on.Additionally, also having lipid-loweringing, hypotensive effect, its hypotensive effect is relevant with nervus centraliss, can Can be for blocking SNE and direct vasodilator.In addition to during blood pressure lowering, electrocardiogram is except having that heart rate is slack-off, t ripple lowers, no bright Aobvious change, toxic dose can make guinea pig heart produce the partial or even completeness retardance of Atrioventricular Conduction.
The effect preserved material of Cortex Lycii of cardiovascular system, tincture and decoct are all had bright to anesthetized dog, cat, intravenous rabbit injection Aobvious hypotensive effect, and with decreased heart rate and accelerated breathing;The effect of preserved material is like better than decoct;Repetitively administered can produce degree The tachylaxis not waited.Concentration tincture also presents to not anesthetized rat gavage to anesthetized dog, cat intramuscular injection or decoct and holds Hypotensive effect stable long.The hypotensive effect of Cortex Lycii is relevant with maincenter to be blocked SNE and directly relaxes it is also possible to have Open the effect of blood vessel.In addition to during blood pressure lowering, electrocardiogram is except having that heart rate is slack-off, t ripple lowers, no significant change, toxic dose can make globefish Rat heart produces the partial or even completeness retardance of Atrioventricular Conduction.
Radix firmianae: there is the effect of expelling wind and removing dampness, regulating menstruation, hemostasis, detoxification sore treatment.It is usually used in Fengshi Guanjie pain, spit blood, Control asthma, discharging fresh blood stool, menoxenia, traumatic injury is pleasant, stomach function regulating, help digestion, hernia, oral aphthae in children." Traditional Chinese Medicine in Sichuan will ": " Along top gas, stomach function regulating.Treat for stomachache."
Pig lean meat: there is the effect of kidney-replenishing blood-nourishing, nourshing Yin and drynsessmoistening prescription;Cure mainly consumption of body fluid caused by febrile disease, weakness and emaciation of quenching one's thirst, kidney deficiency and bodily weakness, blood in puerperal Void, cough caused by dryness, constipation, qi-restoratives, YIN nourishing, moisturize, liver nourishing cloudy, moisten skin, profit two just and is only quenched one's thirst.Carnis Sus domestica boil soup drink under can suddenly mend by Fidgety, dry cough, constipation and the difficult labour causing in deficiency of body fluid.Cholesterol content ratio hog is low by 29%, and contains various trace elements With 17 kinds of aminoacid, the linoleic acid content of needed by human body is higher than 2.5 times of hog.Ecological pig meat-like flavor is strong, and nutritional labeling is complete, There are strong body, tonic effect.
The invention has the beneficial effects as follows:
1) treated according to differential diagnosis in tcm, treating both the principal and secondary aspects of a disease, control the principle supporting combination, improper the putting of dry wolfberry tree root suppression nerve Electricity, and dry Phoenix tree root has the effect of soothing the channels and quicking the network vessels, can be used to treat infant in epileptic attack, the whole body bringing because of convulsions Muscle injury, in addition fresh ecology pig lean meat can supplement the nutrients;
2) the Chinese medicinal decoction fixture that the present invention provides have rapid-action, have no toxic side effect, drug effect is definite, good effect, the advantage not recurred, The damage to cerebral nerve mechanism can be reduced;The present invention draw materials extensively, low cost, preparation simple, there is higher promotional value.
Specific embodiment
With reference to the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, shows So, described embodiment is only embodiments of the invention, and those of ordinary skill in the art are not making creative work Under the premise of the every other embodiment that obtained, broadly fall into the scope of protection of the invention.
Embodiment 1
In the embodiment of the present invention, a kind of Chinese medicine decoction treating children epilepsy, it is made up of the following raw material according to weight portion: dry Chinese holly 43 parts of Qi tree root, 2 parts of dry Phoenix tree root, fresh 200 parts of pig lean meat of ecology.
1) take dry wolfberry tree root and dry Phoenix tree root, cut into pieces after cleaning respectively, then take fresh ecology pig lean meat, clean Section or chopping;2) press respective weight portion to prepare dry wolfberry tree root, dry Phoenix tree root and fresh ecology three kinds of raw materials of pig lean meat Mixing, mixed material is placed in ceramic bowl, adds the spring water of just submergence mixed material, then will fill the pottery of mixed material Bowl is put in pot and is steamed, and places 2.5 hours at 80-100 DEG C;3) mixed material filters after steaming, and obtains final product decoction.
Embodiment 2
In the embodiment of the present invention, a kind of Chinese medicine decoction treating children epilepsy, it is made up of the following raw material according to weight portion: dry Chinese holly 45 parts of Qi tree root, 3 parts of dry Phoenix tree root, fresh 200 parts of pig lean meat of ecology.
1) take dry wolfberry tree root and dry Phoenix tree root, cut into pieces after cleaning respectively, then take fresh ecology pig lean meat, clean Section or chopping;2) press respective weight portion to prepare dry wolfberry tree root, dry Phoenix tree root and fresh ecology three kinds of raw materials of pig lean meat Mixing, mixed material is placed in ceramic bowl, adds the spring water of just submergence mixed material, then will fill the pottery of mixed material Bowl is put in pot and is steamed, and places 2.5 hours at 80-100 DEG C;3) mixed material filters after steaming, and obtains final product decoction.
Embodiment 3
In the embodiment of the present invention, a kind of Chinese medicine decoction treating children epilepsy, it is made up of the following raw material according to weight portion: dry Chinese holly 42 parts of Qi tree root, 2 parts of dry Phoenix tree root, fresh 180 parts of pig lean meat of ecology.
1) take dry wolfberry tree root and dry Phoenix tree root, cut into pieces after cleaning respectively, then take fresh ecology pig lean meat, clean Section or chopping;2) press respective weight portion to prepare dry wolfberry tree root, dry Phoenix tree root and fresh ecology three kinds of raw materials of pig lean meat Mixing, mixed material is placed in ceramic bowl, adds the spring water of just submergence mixed material, then will fill the pottery of mixed material Bowl is put in pot and is steamed, and places 2 hours at 80-100 DEG C;3) mixed material filters after steaming, and obtains final product decoction.
, through the treatment to nearly hundred patients, therapeutic effect is notable, and toxic and side effects are little, and allusion quotation shape case is as follows for the present invention:
1st, patient: what xx, man, one-year-old half, address: Changsha, Hunan illness symptom: first visit was on 2 11st, 2011.2011 On August 22, infants are suffered from diarrhoea suddenly without reason, are diagnosed as normal;The unexpected syncope of on December 2nd, 2011 infant, partly open, eyeball On turn over, gnathospasma, bicker twitch, head to layback, extremity bend and stretch repeatedly, continue more than ten seconds, afterwards slowly revival, action extensive Multiple normal;Infant recurs again within 2 10th, 2011.Treatment: take above-mentioned Chinese medicine decoction, one daily, after three doses of medication Recurrence that so far there are no.
2nd, patient: Lee xx, female, six years old, address: Guangzhou, Guangdong illness symptom: first visit was in August in 2013 23 days. On June 2nd, 2013 infant no suddenly children's syncope, partly open, eyeball turns over, gnathospasma, bicker twitch, head to layback, Extremity bend and stretch repeatedly, continue more than ten seconds, and slowly revival, action recover normal afterwards;By weekly slowly deteriorating it is afterwards The recurrence of one day two or three times;Its household carries her to see a doctor to various big hospital, all cannot be carried out making a definite diagnosis, and therefore also cannot be carried out treating. Treatment: take above-mentioned Chinese medicine decoction, one daily, recurrence that after eight doses of medication, so far there are no.
Above it should be understood that although this specification is been described by according to embodiment, but not each embodiment only wraps Containing an independent technology official documents and correspondence, only for clarity, those skilled in the art should for this narrating mode of description Using description as an entirety, the technical scheme in each embodiment can also form those skilled in the art through appropriately combined Understandable other embodiment.

Claims (5)

1. a kind of Chinese medicine decoction treating children epilepsy is it is characterised in that be made up of the following raw material according to weight portion: dry wolfberry Tree root 35-50 part, dry Phoenix tree root 1-5 part, fresh ecology pig lean meat 150-250 part.
2. a kind of Chinese medicine decoction treating children epilepsy according to claim 1 is it is characterised in that by following according to weight The raw material composition of part: dry wolfberry tree root 40-45 part, dry Phoenix tree root 1-3 part, fresh ecology pig lean meat 180-220 part.
3. a kind of Chinese medicine decoction treating children epilepsy according to claim 1 is it is characterised in that by following according to weight The raw material composition of part: 43 parts of dry wolfberry tree root, 2 parts of dry Phoenix tree root, fresh 200 parts of pig lean meat of ecology.
4. the preparation method according to a kind of arbitrary described Chinese medicine decoction treating children epilepsy of claim 1-3, its feature exists In comprising the steps of: 1) take dry wolfberry tree root and dry Phoenix tree root, cut into pieces after cleaning respectively, then take fresh ecology Pig lean meat, cleans section or shreds;2) press respective weight portion to prepare dry wolfberry tree root, dry Phoenix tree root and fresh ecological pig Three kinds of raw material mixing of lean meat, mixed material are placed in ceramic bowl, add the spring water of just submergence mixed material, then will fill mixed The ceramic bowl closing raw material puts into steaming in pot, places 2-2.5 hour at 80-100 DEG C;3) mixed material filters after steaming, and obtains final product Decoction.
5. according to a kind of arbitrary described Chinese medicine decoction treating children epilepsy of claim 1-3 in preparation treatment children epilepsy medicine Application in thing.
CN201610949079.1A 2016-10-26 2016-10-26 Traditional Chinese medicine decoction for treating pediatric epilepsy, and preparation method and application thereof Pending CN106361892A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1279968A (en) * 2000-04-21 2001-01-17 张艳 Chinese medicine for curing epilepsy and its producing method
CN1615949A (en) * 2004-09-16 2005-05-18 唐玉厚 Medicine for treating epilepsia
CN103316225A (en) * 2013-06-21 2013-09-25 王辉 Traditional Chinese medicine for treating epilepsy and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1279968A (en) * 2000-04-21 2001-01-17 张艳 Chinese medicine for curing epilepsy and its producing method
CN1615949A (en) * 2004-09-16 2005-05-18 唐玉厚 Medicine for treating epilepsia
CN103316225A (en) * 2013-06-21 2013-09-25 王辉 Traditional Chinese medicine for treating epilepsy and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王贵淼等: "《家庭良方》", 28 February 1983, 浙江科学技术出版社出版 *

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