CN106310240A - Chelated iron capsule for resolving depression and tonifying yang and preparing method thereof - Google Patents
Chelated iron capsule for resolving depression and tonifying yang and preparing method thereof Download PDFInfo
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Abstract
The invention discloses a Chelated iron capsule for resolving depression, prepared from the following ingredients, by weight: 50-60 parts of water-chestnut, 20-25 parts of pumpkin seed, 70-80 parts of pagodatree flower bud, 20-30 parts of beef powder, 35-38 parts of black tea juice, 220- 300 parts of fresh pig blood, 5-7 parts of 2709 alkaline protease, 25-30 parts of ferrous chloride, 1.2-2.3 parts of cortex albiziae, 1.6-2.1 parts of tangerine pith, 1.6-2 parts of cassia twig. Anti-anemia effect of the invented care preparing is significantly better than ferrous gluconate and ferrous chloride, and amino acids and small molecular peptides can promote the absorption of iron, so as to improve the effect of iron. Therefore, it is ideal iron preparings, applicable to improve iron-deficiency nutritional anemia; the invention effectively utilizes the waste resources, indirectly protects the environment, and improves the utilization rate of resources.
Description
Technical field
The present invention relates to health medicine technical field, particularly relate to a kind of resolving depression Yiyang chelated iron capsule and preparation side thereof
Method.
Background technology
At present, the preventing and treating of iron deficiency anemia mainly realizes by taking iron supplementary.Existing iron supplementary have ferrous sulfate,
Ferrous chloride, Ferrous gluconate, ferrous lactate etc., although these iron supplementary iron contents are high, but due to them in vivo
Utilization rate is relatively low, and there is metal rust taste in various degree and GI irritation, and research shows, polypeptide chelate iron is a kind of
Novel biology iron, can directly be absorbed by intestinal mucosa cells, and not producing digestive tract stimulates, and bioavailability is high, is preferable
Iron supplementary.
The blood flowed out after slaughtering animal is mainly used in making dish, blood powder, blood sausage and blood beans by China's many slaughterhouses
Oil etc., added value of product is low, also has quite a few blood to be directly discharged into environment, has both wasted the protein resource of preciousness, again
Severe contamination environment around, therefore, utilizes animal blood to prepare polypeptide ferrum to improving the added value of Sanguis sus domestica, profit to Sanguis sus domestica
Have great significance with preserving the ecological environment with going on industrialized developing road.
Summary of the invention
The object of the invention is contemplated to make up the defect of prior art, it is provided that a kind of resolving depression Yiyang chelated iron capsule and system thereof
Preparation Method.
The present invention is achieved by the following technical solutions:
A kind of resolving depression Yiyang chelated iron capsule, is prepared by the raw materials in:
Horse hoof 50-60, Semen Cucurbitae 20-25, Flos Sophorae Immaturus 70-80, beef powder 20-30, black tea draw-off juice 35-38, fresh Sanguis sus domestica 220-300,
2709 alkaline protease 5-7, ferrous chloride 25-30, Cortex Albiziae 1.2-2.3, Vascular aurantii 1.6-2.1, Ramulus Cinnamomi 1.6-2.
The preparation method of described a kind of resolving depression Yiyang chelated iron capsule, comprises the following steps:
(1) by after Cortex Albiziae, Vascular aurantii, the Ramulus Cinnamomi flooding by 6-9 times amount, medicine juice is filtered to obtain, more spray-dried, obtain Chinese medicine
Powder；
(2) take the clean Flos Sophorae Immaturus to mix homogeneously with beef powder, then be placed on food steamer and fumigate 20-22 minute with black tea draw-off juice；Obtain pot
The interior steamed Flos Sophorae Immaturus, freeze-dried, then pulverize；
(3) take Horse hoof peeling stripping and slicing, Semen Cucurbitae shell is separated with core, pumpkin seed is mixed with the Horse hoof handled well and is placed in squeezing slurry
In machine, being blended into 4-5 times of water, serosity is squeezed in mixing；
(4) taking fresh Sanguis sus domestica, add the sodium citrate of its weight 0.4-0.5%, 2500-3000r/min is centrifuged 14-15min, abandons
Clear liquid, precipitate normal saline cleans, and is subsequently adding the distilled water of 3-4 times of volume, stirs, 50-60 under the conditions of lucifuge
DEG C heating 25-30min, obtain hemoglobin solutions；
(5) above-mentioned hemoglobin solutions is joined in 100-120 times of water, be placed in 40-50 DEG C of water-bath, add mixed liquor weight
2709 alkaline proteases of 2-3%, are 10-11 with sodium hydroxide regulation PH, and insulation reaction 6-7 hour adds acetic acid and adjusts pH value extremely
4-4.5, is incubated 18-20min at 90-95 DEG C, is cooled to room temperature, and 3500-4000r/min is centrifuged 2-3min, takes supernatant, adds
Enter the activated carbon of supernatant weight 1.5-2%, decolour two hours at 45-50 DEG C, sucking filtration, obtain destaining solution；
(6) take above-mentioned destaining solution, add the ascorbic acid of its liquor capacity 1-2%, be subsequently adding ferrous chloride, regulate with acetic acid
PH is 5-5.5, is passed through nitrogen, at room temperature hybrid reaction 8-10min, centrifugal 18-20min under 3500-4000r/min,
The supernatant obtained adds the dehydrated alcohol of its volume 3-5 times, stirring mixing 3-4 hour, sucking filtration, vacuum drying, obtains polypeptide
Chelate iron；
(7) above-mentioned steps gained Semen Cucurbitae shell is dried pulverizing, collect stand-by;
(8) by regrinding after above-mentioned steps gained material mix homogeneously, obtain fine powder, and load capsule, every heavy 1-1.2 gram,
Obtain.
The invention have the advantage that health preparation anti-anemia action effect of the present invention is significantly better than Ferrous gluconate and protochloride
Ferrum, aminoacid and micromolecule polypeptide more can promote the absorption of ferrum, thus improve iron supplement effect, so being comparatively ideal iron supplement system
Agent, it is adaptable to improve iron-deficient nutrition anemia；The present invention is effectively utilized waste resource, indirect protection environment, improves money
Source utilization rate；
Iron supplement of the present invention is effective, is suitable for crowd extensive, and health-care effect ideal has been also added with the food medicines such as Cortex Albiziae, Vascular aurantii, Ramulus Cinnamomi
Material, richness has given resolving stagnation for tranquilization of the present invention, promoting blood circulation and detumescence, activating QI to eliminate phlegm, complement sun, promoting blood circulation, the health-care effect of warming the spleen and stomach.
Detailed description of the invention
A kind of resolving depression Yiyang chelated iron capsule, is prepared by the raw materials in:
Horse hoof 50, Semen Cucurbitae 20, the Flos Sophorae Immaturus 70, beef powder 20, black tea draw-off juice 35, fresh Sanguis sus domestica 220,2709 alkaline protease 5, chlorination
Ferrous iron 25, Cortex Albiziae 1.2, Vascular aurantii 1.6, Ramulus Cinnamomi 1.6.
The preparation method of described a kind of resolving depression Yiyang chelated iron capsule, comprises the following steps:
(1) by after Cortex Albiziae, Vascular aurantii, the Ramulus Cinnamomi flooding by 6 times amount, medicine juice is filtered to obtain, more spray-dried, obtain Chinese medicine powder；
(2) take the clean Flos Sophorae Immaturus to mix homogeneously with beef powder, then be placed on food steamer and fumigate 20 minutes with black tea draw-off juice；Steam in obtaining pot
The good Flos Sophorae Immaturus, freeze-dried, then pulverize；
(3) take Horse hoof peeling stripping and slicing, Semen Cucurbitae shell is separated with core, pumpkin seed is mixed with the Horse hoof handled well and is placed in squeezing slurry
In machine, being blended into 4 times of water, serosity is squeezed in mixing；
(4) taking fresh Sanguis sus domestica, add the sodium citrate of its weight 0.4%, 2500r/min is centrifuged 14min, abandons supernatant, and precipitate is used
Normal saline cleans, and is subsequently adding the distilled water of 3 times of volumes, stirs, and under the conditions of lucifuge, 50 DEG C of heating 25min, obtain blood
Hemoglobin solution；
(5) above-mentioned hemoglobin solutions is joined in 100 times of water, be placed in 40 DEG C of water-baths, add mixed liquor weight 2%
2709 alkaline proteases, are 10 with sodium hydroxide regulation PH, insulation reaction 6 hours, and addition acetic acid tune pH value is to 4,90 DEG C of guarantors
Temperature 18min, is cooled to room temperature, and 3500r/min is centrifuged 2min, takes supernatant, adds the activated carbon of supernatant weight 1.5%,
Decolour two hours at 45 DEG C, sucking filtration, obtain destaining solution；
(6) take above-mentioned destaining solution, add the ascorbic acid of its liquor capacity 1%, be subsequently adding ferrous chloride, use vinegar acid for adjusting pH
Being 5, be passed through nitrogen, at room temperature hybrid reaction 8min, under 3500r/min, centrifugal 18min, adds in the supernatant obtained
The dehydrated alcohol of its volume 3 times, stirring mixing 3 hours, sucking filtration, vacuum drying, obtain polypeptide chelate iron；
(7) above-mentioned steps gained Semen Cucurbitae shell is dried pulverizing, collect stand-by;
(8) by regrinding after above-mentioned steps gained material mix homogeneously, obtain fine powder, and load capsule, every weight 1 gram, to obtain final product.
Claims (2)
1. resolving depression Yiyang chelated iron capsule, it is characterised in that be prepared by the raw materials in:
Horse hoof 50-60, Semen Cucurbitae 20-25, Flos Sophorae Immaturus 70-80, beef powder 20-30, black tea draw-off juice 35-38, fresh Sanguis sus domestica 220-300,
2709 alkaline protease 5-7, ferrous chloride 25-30, Cortex Albiziae 1.2-2.3, Vascular aurantii 1.6-2.1, Ramulus Cinnamomi 1.6-2.
The preparation method of a kind of resolving depression Yiyang the most as claimed in claim 1 chelated iron capsule, it is characterised in that include following step
Rapid:
(1) by after Cortex Albiziae, Vascular aurantii, the Ramulus Cinnamomi flooding by 6-9 times amount, medicine juice is filtered to obtain, more spray-dried, obtain Chinese medicine
Powder；
(2) take the clean Flos Sophorae Immaturus to mix homogeneously with beef powder, then be placed on food steamer and fumigate 20-22 minute with black tea draw-off juice；Obtain pot
The interior steamed Flos Sophorae Immaturus, freeze-dried, then pulverize；
(3) take Horse hoof peeling stripping and slicing, Semen Cucurbitae shell is separated with core, pumpkin seed is mixed with the Horse hoof handled well and is placed in squeezing slurry
In machine, being blended into 4-5 times of water, serosity is squeezed in mixing；
(4) taking fresh Sanguis sus domestica, add the sodium citrate of its weight 0.4-0.5%, 2500-3000r/min is centrifuged 14-15min, abandons
Clear liquid, precipitate normal saline cleans, and is subsequently adding the distilled water of 3-4 times of volume, stirs, 50-60 under the conditions of lucifuge
DEG C heating 25-30min, obtain hemoglobin solutions；
(5) above-mentioned hemoglobin solutions is joined in 100-120 times of water, be placed in 40-50 DEG C of water-bath, add mixed liquor weight
2709 alkaline proteases of 2-3%, are 10-11 with sodium hydroxide regulation PH, and insulation reaction 6-7 hour adds acetic acid and adjusts pH value extremely
4-4.5, is incubated 18-20min at 90-95 DEG C, is cooled to room temperature, and 3500-4000r/min is centrifuged 2-3min, takes supernatant, adds
Enter the activated carbon of supernatant weight 1.5-2%, decolour two hours at 45-50 DEG C, sucking filtration, obtain destaining solution；
(6) take above-mentioned destaining solution, add the ascorbic acid of its liquor capacity 1-2%, be subsequently adding ferrous chloride, regulate with acetic acid
PH is 5-5.5, is passed through nitrogen, at room temperature hybrid reaction 8-10min, centrifugal 18-20min under 3500-4000r/min,
The supernatant obtained adds the dehydrated alcohol of its volume 3-5 times, stirring mixing 3-4 hour, sucking filtration, vacuum drying, obtains polypeptide
Chelate iron；
(7) above-mentioned steps gained Semen Cucurbitae shell is dried pulverizing, collect stand-by;
(8) by regrinding after above-mentioned steps gained material mix homogeneously, obtain fine powder, and load capsule, every heavy 1-1.2 gram,
Obtain.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610713571.9A CN106310240A (en) | 2016-08-24 | 2016-08-24 | Chelated iron capsule for resolving depression and tonifying yang and preparing method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610713571.9A CN106310240A (en) | 2016-08-24 | 2016-08-24 | Chelated iron capsule for resolving depression and tonifying yang and preparing method thereof |
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| CN106310240A true CN106310240A (en) | 2017-01-11 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107691761A (en) * | 2017-11-09 | 2018-02-16 | 桐城市雨润生物科技有限公司 | A kind of pig blood chelates rich ferritin powder and preparation method thereof |
| US10472596B2 (en) | 2017-06-27 | 2019-11-12 | Ecolab Usa Inc. | Non-phosphorous transition metal control in laundry applications |
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| CN101375702A (en) * | 2008-09-12 | 2009-03-04 | 中国农业大学 | Hemoglobin polypeptide powder and preparation method thereof |
| CN101731628A (en) * | 2010-01-19 | 2010-06-16 | 浙江大学 | Method for preparing casein peptide chelated iron |
| CN102051392A (en) * | 2009-10-29 | 2011-05-11 | 上海鸿儒科技发展有限公司 | Chlorhematin and preparation method thereof as well as blood-enriching pharmaceutical composition |
| CN105420323A (en) * | 2015-12-23 | 2016-03-23 | 吉林大学 | Phytochelatin iron supplementation powder containing iron and preparation method of phytochelatin iron supplementation powder |
| CN105561286A (en) * | 2016-01-20 | 2016-05-11 | 吉林大学 | Red date iron replenishment drink containing peptide and iron-chelating peptide and preparation method |
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2016
- 2016-08-24 CN CN201610713571.9A patent/CN106310240A/en active Pending
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|---|---|---|---|---|
| CN101375702A (en) * | 2008-09-12 | 2009-03-04 | 中国农业大学 | Hemoglobin polypeptide powder and preparation method thereof |
| CN102051392A (en) * | 2009-10-29 | 2011-05-11 | 上海鸿儒科技发展有限公司 | Chlorhematin and preparation method thereof as well as blood-enriching pharmaceutical composition |
| CN101731628A (en) * | 2010-01-19 | 2010-06-16 | 浙江大学 | Method for preparing casein peptide chelated iron |
| CN105420323A (en) * | 2015-12-23 | 2016-03-23 | 吉林大学 | Phytochelatin iron supplementation powder containing iron and preparation method of phytochelatin iron supplementation powder |
| CN105561286A (en) * | 2016-01-20 | 2016-05-11 | 吉林大学 | Red date iron replenishment drink containing peptide and iron-chelating peptide and preparation method |
Non-Patent Citations (1)
| Title |
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| 郑炯: "血红蛋白多肽螯合铁的制备及其抗贫血功能研究", 《中国优秀硕士学位论文全文数据库 工程科技Ⅰ辑》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10472596B2 (en) | 2017-06-27 | 2019-11-12 | Ecolab Usa Inc. | Non-phosphorous transition metal control in laundry applications |
| CN107691761A (en) * | 2017-11-09 | 2018-02-16 | 桐城市雨润生物科技有限公司 | A kind of pig blood chelates rich ferritin powder and preparation method thereof |
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Application publication date: 20170111 |