CN106305717A - Disinfectant special for hand-foot-mouth viruses - Google Patents
Disinfectant special for hand-foot-mouth viruses Download PDFInfo
- Publication number
- CN106305717A CN106305717A CN201610645326.9A CN201610645326A CN106305717A CN 106305717 A CN106305717 A CN 106305717A CN 201610645326 A CN201610645326 A CN 201610645326A CN 106305717 A CN106305717 A CN 106305717A
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- CN
- China
- Prior art keywords
- foot
- hand
- liquid
- mouth disease
- disease virus
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
- A01N31/16—Oxygen or sulfur directly attached to an aromatic ring system with two or more oxygen or sulfur atoms directly attached to the same aromatic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/02—Acyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to the field of prevention, diagnosis and treatment of hand-foot-mouth diseases, in particular to a formula and preparation method of a disinfectant special for hand-foot-mouth viruses. The disinfectant is prepared from, by weight, 0.3-0.6% of trichloro hydroxydiphenyl ether, 15-60% of alcohol, 1.0-5.0% of an acidity conditioning agent, 0.5-3.0% of a surface active agent, 0.5-3.0% of a humectant and the balance water. The trichloro hydroxydiphenyl ether is dissolved into the alcohol and stirred to be uniform to obtain a solution A; the acidity conditioning agent, the surface active agent and the humectant are added into the water and stirred to be uniform to obtain a solution B; the solution A is added into the solution B to be stirred for 2 h, and packaging can be performed till uniform and colorless transparent liquid is obtained. The disinfectant can effectively kill hand-foot-mouth viruses, is high in sterilization speed and high in drying speed, will not pollute the environment, is free of non-toxic grade practically, has no toxic or side effect on the human body, and has the skin care effect.
Description
Technical field
The present invention relates to hand-foot-mouth disease prevention and diagnosis and treatment field, particularly to a kind of Special sterilizing killing hand-foot-mouth disease virus
The formula of liquid and preparation method.
Background technology
Hand-foot-mouth disease is global infectious disease, and the four seasons all can fall ill, especially with summer and autumn common.In recent years, hand-foot-mouth disease
It is domestic common epidemic infectious diseases, is common in less than 5 years old child, this sick popular period, kindergarten and nursery school can occur
Group contagion and family controller morbidity, severe patient can cause the diseases such as myocarditis, pulmonary edema, meningitis.
Domestic there is presently no is specifically designed to the disinfectant solution killing hand-foot-mouth disease virus, and people kill hand-foot-mouth disease virus in selection
Disinfectant solution time some blindly.
During prevention hand-foot-mouth disease, owing to not killing the Special sterilizing liquid of hand-foot-mouth disease virus, people are often according to routine
Preventive measure prevention hand-foot-mouth disease, such as with 75% alcohol disinfection solution, lysol disinfectant solution, chlorine-containing disinfectant, ultraviolet photograph
The method such as penetrate.But these conventional measures all exist certain defect, people do not accomplish the effective prevention to hand-foot-mouth disease, such as
Brothers' Aphthovirus is not acted on by 75% alcohol disinfection solution, lysol disinfectant solution etc.；Chlorine-containing disinfectant is big to skin irritation；Purple
Outside line radiation time length, carry and in-convenience in use.
Treatment stage, also not used for the Special sterilizing liquid for the treatment of hand-foot-mouth disease.Medical personnel are general when treating to infant
Can select iodine-containing disinfectant or hand disinfectant product, but on market, Operand or the hands series products that disappears is a lot, the formula of different manufacturers,
Quality control standard is the most different, it is possible to the iodine-containing disinfectant of medical personnel's selection or hand disinfectant product can not kill
Hand-foot-mouth disease virus.
It addition, medical personnel are before and after to hand-foot-mouth disease infant diagnosis and treatment, it is intended to carry out the sterilization of hand, if the hands selected
Disinfectant solution can not effectively kill hand-foot-mouth disease virus, the most easily causes the propagation of hand-foot-mouth disease.
Summary of the invention
It is an object of the invention to provide a kind of hand-foot-mouth disease virus Special sterilizing liquid and preparation method thereof.The sterilization of the present invention
Liquid can not only quickly kill hand-foot-mouth disease virus, and has good safety, has no side effect human body, easy to use soon
Prompt.
A kind of hand-foot-mouth disease virus Special sterilizing liquid, it includes the component of following each percetage by weight:
Trichloro hydroxyl diphenyl ether: 0.3%～0.6%
Alcohol: 15%～60%
Acid regulator: 1.0%～5.0%
Surfactant: 0.5%～3.0%
Wetting agent: 0.5%～3.0%
Water: surplus
The present invention uses wide-spectrum bactericide trichloro hydroxyl diphenyl ether to be major antibacterial agent, then be aided with sterilization extensively, effect can
The ethanol leaned on or isopropanol, play the synergic remove of its two kinds of Fungicidal substances, more efficient kills hand-foot-mouth disease virus, reaches
Prevent and treat the purpose of hand-foot-mouth disease.
The present invention uses acid regulator to be to regulate disinfectant solution pH range to 2.0～4.0 so that it is can play this
The maximum bactericidal effect of invention, acid regulator can use one or more in lactic acid, malic acid, tartaric acid, sorbic acid.
The present invention uses surfactant to contribute to strengthening the trichloro hydroxyl diphenyl ether penetrating power to brothers' Aphthovirus, by force
Change the sterilizing ability of the present invention, more effectively kill hand-foot-mouth disease virus, additionally aid the lasting sterilizing ability of enhancing, surface activity simultaneously
Agent can use the one in cocoanut fatty acid diethanolamide, fatty alcohol-polyoxyethylene ether, alkylphenol polyoxyethylene or
Several.
The present invention uses wetting agent to help to maintain the moistening of skin, is effectively improved maculopapule, bleb that hand-foot-mouth disease causes
The rash infringement to skin, wetting agent can use in aloe, shea butter, Mel, Sorbitol, propylene glycol, glycerol
One or more.
The preparation method of any one hand-foot-mouth disease virus Special sterilizing liquid of the present invention, by described each component and content:
(1) trichloro hydroxyl diphenyl ether being dissolved in alcohol, stir to obtain A liquid；
(2) acid regulator, surfactant, wetting agent being added to the water, stir to obtain B liquid；
(3) A liquid is joined in B liquid, stir 2 hours, get final product fill to uniform colorless transparency liquid.
The present invention can quickly, effectively kill hand-foot-mouth disease virus, and rate of drying is fast, stability is high, environmentally safe, reality
Nontoxic level, to human non-toxic's side effect, have skin care effect simultaneously.The present invention can be used for the skin degerming of hand-foot-mouth disease patient；Medical matters
Personnel in diagnosis and treatment, nurse the sick before and after's hand-wrist bones；Non-disposable instrument used in diagnosis and treatment, the process that nurses the sick, article
And the sterilization of the facility such as sick bed, tables and chairs；Prophylactic disinfection；Can effectively prevent infection and the outburst of hand-foot-mouth disease.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be further described:
The present invention provides a kind of hand-foot-mouth disease virus Special sterilizing liquid, and it includes the component of following each percetage by weight:
Trichloro hydroxyl diphenyl ether: 0.3%～0.6%
Alcohol: 15%～60%
Acid regulator: 1.0%～5.0%
Surfactant: 0.5%～3.0%
Wetting agent: 0.5%～3.0%
Water: surplus
Embodiment 1
(1) weigh trichloro hydroxyl diphenyl ether 2.5kg, join and 80L ethanol is stirred well to all dissolve, obtain A liquid；
(2) weigh 21kg lactic acid, cocoanut fatty acid diethanolamide 10kg, Sorbitol 500g join 100kg water
In be stirred well to all dissolve and obtain B liquid；
(3) B liquid is joined in the A liquid being stirred continuously, add water to 500L, be sufficiently stirred for mixing and i.e. obtain disinfectant solution.
Embodiment 2
(1) weigh trichloro hydroxyl diphenyl ether 2.5kg, join 10L isopropanol, 200L ethanol are stirred well to the most molten
Solution obtains A liquid；
(2) weigh 20kg malic acid, alkylphenol polyoxyethylene 1kg, propylene glycol 500g join in 100kg water and fully stir
Mix to all dissolving and obtain B liquid；
(3) B liquid is joined in the A liquid being stirred continuously, add water to 500L, be sufficiently stirred for mixing and i.e. obtain disinfectant solution.
Claims (6)
1. a hand-foot-mouth disease virus Special sterilizing liquid, it includes the component of following each percetage by weight:
Trichloro hydroxyl diphenyl ether: 0.3%～0.6%
Alcohol: 15%～60%
Acid regulator: 1.0%～5.0%
Surfactant: 0.5%～3.0%
Wetting agent: 0.5%～3.0%
Water: surplus.
A kind of hand-foot-mouth disease virus Special sterilizing liquid the most according to claim 1, is characterized in that: alcohol use 95% ethanol or
Isopropanol.
A kind of hand-foot-mouth disease virus Special sterilizing liquid the most according to claim 1, is characterized in that: acid regulator uses breast
One or more in acid, malic acid, tartaric acid, sorbic acid.
A kind of hand-foot-mouth disease virus Special sterilizing liquid the most according to claim 1, is characterized in that: surfactant uses Cortex cocois radicis
One or more in fatty acid oil diglycollic amide, fatty alcohol-polyoxyethylene ether, alkylphenol polyoxyethylene.
A kind of hand-foot-mouth disease virus Special sterilizing liquid the most according to claim 1, is characterized in that: wetting agent employing aloe,
One or more in shea butter, Mel, Sorbitol, propylene glycol, glycerol.
6. according to the preparation method of a kind of hand-foot-mouth disease virus Special sterilizing liquid described in any claim in claim 1 to 5,
It is characterized in that:
(1) trichloro hydroxyl diphenyl ether being dissolved in alcohol, stir to obtain A liquid；
(2) acid regulator, surfactant, wetting agent being added to the water, stir to obtain B liquid；
(3) A liquid is joined in B liquid, stir 2 hours, get final product fill to uniform colorless transparency liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610645326.9A CN106305717A (en) | 2016-08-02 | 2016-08-02 | Disinfectant special for hand-foot-mouth viruses |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610645326.9A CN106305717A (en) | 2016-08-02 | 2016-08-02 | Disinfectant special for hand-foot-mouth viruses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106305717A true CN106305717A (en) | 2017-01-11 |
Family
ID=57739620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610645326.9A Pending CN106305717A (en) | 2016-08-02 | 2016-08-02 | Disinfectant special for hand-foot-mouth viruses |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106305717A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107372495A (en) * | 2017-08-07 | 2017-11-24 | 马洪训 | Wide spectrum disease control disinfection solution |
| CN109288822A (en) * | 2018-08-24 | 2019-02-01 | 杭州氢源素生物科技有限公司 | A kind of viral Special sterilizing liquid and preparation method thereof containing polyglycerol ester |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1264292A (en) * | 1997-06-04 | 2000-08-23 | 普罗克特和甘保尔公司 | Leave-on antimicrobial compositons |
| CN101091487A (en) * | 2007-06-18 | 2007-12-26 | 四川大学 | Antisepsis spraying agent in use for die plate of alginate, and preparation method |
| CN101658469A (en) * | 2009-09-10 | 2010-03-03 | 上海泛亚生命科技有限公司 | Cleaning-free hand sanitizer and preparation thereof |
| CN104604849A (en) * | 2015-02-15 | 2015-05-13 | 中国人民解放军疾病预防控制所 | Handwash-free disinfectant and preparation method thereof |
-
2016
- 2016-08-02 CN CN201610645326.9A patent/CN106305717A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1264292A (en) * | 1997-06-04 | 2000-08-23 | 普罗克特和甘保尔公司 | Leave-on antimicrobial compositons |
| CN101091487A (en) * | 2007-06-18 | 2007-12-26 | 四川大学 | Antisepsis spraying agent in use for die plate of alginate, and preparation method |
| CN101658469A (en) * | 2009-09-10 | 2010-03-03 | 上海泛亚生命科技有限公司 | Cleaning-free hand sanitizer and preparation thereof |
| CN104604849A (en) * | 2015-02-15 | 2015-05-13 | 中国人民解放军疾病预防控制所 | Handwash-free disinfectant and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107372495A (en) * | 2017-08-07 | 2017-11-24 | 马洪训 | Wide spectrum disease control disinfection solution |
| CN109288822A (en) * | 2018-08-24 | 2019-02-01 | 杭州氢源素生物科技有限公司 | A kind of viral Special sterilizing liquid and preparation method thereof containing polyglycerol ester |
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| Date | Code | Title | Description |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information | ||
| CB02 | Change of applicant information |
Address after: 253000 Shandong city of Dezhou province Dexing Tianqu Industrial Park Road No. 268 Applicant after: Shandong Anjie tech Disinfection Technology Co. Ltd. Address before: 253000 Shandong city of Dezhou province Dexing Tianqu Industrial Park Road No. 268 Applicant before: Prompt high-tech sterilized articles therefrom Co., Ltd is pacified in Dezhou |
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| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170111 |