CN106267077B - A kind of Chinese medicine composition for treating mesenteric lymphadenitis and its preparation and application - Google Patents
A kind of Chinese medicine composition for treating mesenteric lymphadenitis and its preparation and application Download PDFInfo
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Classifications
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Abstract
The invention discloses a kind of Chinese medicine composition for treating mesenteric lymphadenitis and its preparation and application, the Chinese medicine composition includes the bulk drug of following parts by weight：50~150 parts of dark plum, 100~200 parts of corydalis tuber, 100~200 parts of root tuber of aromatic turmeric, 20~40 parts of cooked aconite, 50~150 parts of cassia twig, 50~150 parts of golden cypress, 20~40 parts of the coptis, 50~150 parts of Radix Angelicae Sinensis, 40~60 parts of pericarpium zanthoxyli, 40~60 parts of rhizoma zingiberis, 15~25 parts of asarum, 100~200 parts of fructus toosendan, 100~200 parts of betel nut.Scientific compatibility of the present invention, each component mutually act synergistically, and anti-inflammatory analgetic, antibacterial detumescence, expelling wind and clearing away cold, clearing heat and detoxicating, benefit yang transforming qi, have the effect of splendid to treatment mesenteric lymphadenitis, cure rate is high, and takes safety.In addition, the Chinese medicine composition of the present invention can be made into a variety of formulations, it is further preferred that, can meet the needs of different patients the effect of capsule.It is also excellent the effect of traditional Chinese medicine composition for treating roundworm disease of the present invention through clinical discovery in addition.
Description
Technical field
The present invention relates to tcm field, more particularly to a kind of Chinese medicine composition and its system for treating mesenteric lymphadenitis
Agent and application.
Background technology
Mesenterium is made up of parietal layer and visceral peritoneum, mainly there is mesostenium and mesocolon, in addition with mesoappendix and
Ovary, mesosalpinx etc..Mesostenium is the peritonaeum for connecting jejunum, ileum and posterior abdominal wall, in sector, is attached to posterior wall of abdomen
Root of mesentery is in part, small intestine edge 6~7m of length of mesentery, inside have on mesenterium artery and vein and its branch, lacteal vessel, neuropile and
Lymph node etc..Mesenterium has abundant lymph distribution, and lymphatic vessel comes from the center in intestinal mucosa capillary clump or intestinal villi
Lacteal vessel, gone together with mesenteric vein, drain into mesentery root lymph node or paraaortic lymph nodes, then through cisterna chyli,
Ductus thoracicus and enter blood circulation.When virus or bacterium infection involve lymphonodi mesenterici, mesenteric lymphadenitis can be produced.It is existing
In technology, mainly using the Western medicine such as anti-infective, antiviral as main treatment, its cure rate is low, and side effect is big, and cures the symptoms, not the disease.
The content of the invention
In view of this, the invention provides a kind of Chinese medicine composition for treating mesenteric lymphadenitis and its preparation and should
With for described Chinese medicine composition to having the effect of splendid to treatment mesenteric lymphadenitis, cure rate is high, and takes safety.
The technological means that the present invention uses is as follows：A kind of Chinese medicine composition for treating mesenteric lymphadenitis, including it is following
The bulk drug of parts by weight：50~150 parts of dark plum, 100~200 parts of corydalis tuber, 100~200 parts of root tuber of aromatic turmeric, 20~40 parts of cooked aconite, osmanthus
50~150 parts of branch, 50~150 parts of golden cypress, 20~40 parts of the coptis, 50~150 parts of Radix Angelicae Sinensis, 40~60 parts of pericarpium zanthoxyli, rhizoma zingiberis 40~60
Part, 15~25 parts of asarum, 100~200 parts of fructus toosendan, 100~200 parts of betel nut.
Preferably, the Chinese medicine composition of the treatment mesenteric lymphadenitis, the bulk drug of following parts by weight is included：Dark plum
80~120 parts, 120~180 parts of corydalis tuber, 120~180 parts of root tuber of aromatic turmeric, 25~35 parts of cooked aconite, 80~120 parts of cassia twig, golden cypress 80~
120 parts, 25~35 parts of the coptis, 80~120 parts of Radix Angelicae Sinensis, 45~55 parts of pericarpium zanthoxyli, 45~55 parts of rhizoma zingiberis, 18~22 parts of asarum, river
Sub 120~180 parts, 120~180 parts of betel nut.
Preferably, the Chinese medicine composition of the treatment mesenteric lymphadenitis, the bulk drug of following parts by weight is included：Dark plum
100 parts, 150 parts of corydalis tuber, 150 parts of root tuber of aromatic turmeric, 30 parts of cooked aconite, 100 parts of cassia twig, 100 parts of golden cypress, 30 parts of the coptis, 100 parts of Radix Angelicae Sinensis,
50 parts of pericarpium zanthoxyli, 50 parts of rhizoma zingiberis, 20 parts of asarum, 150 parts of fructus toosendan, 150 parts of betel nut.
Present invention also offers a kind of Chinese medicinal composition preparation for treating mesenteric lymphadenitis, comprising provided by the invention
The Chinese medicine composition for the treatment of mesenteric lymphadenitis described in any one, the Chinese medicine composition of the treatment mesenteric lymphadenitis
Preparation is granule, oral liquid, pill, one kind of capsule.
Present invention also offers it is described treatment mesenteric lymphadenitis Chinese medicine composition treatment mesenteric lymphadenitis,
Application in roundworm disease.
Beneficial effect：The invention provides a kind of Chinese medicine composition for treating mesenteric lymphadenitis, the Chinese medicine group
In compound dark plum astringe the lung, puckery intestines, claming ascaris, corydalis tuber promoting blood circulation, promoting the circulation of qi, analgesic, root tuber of aromatic turmeric promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral, the cool blood that clears away heart-fire, profit
Courage removing jaundice, cooked aconite mends fire supporing yang, dispelling cold and removing dampness, cassia twig warming meridian, helps yang transforming qi, flat gas that spins, golden cypress heat-clearing and damp-drying drug, rush down
Fire except steaming, detoxifying, invigorate blood circulation, relieve pain, relax bowel, and pericarpium zanthoxyli warming spleen and stomach for dispelling cold, stops by coptis heat-clearing and damp-drying drug, purging intense heat and detonicating, Chinese angelica blood supplementing
Bitterly, eliminating dampness, desinsection, rhizoma zingiberis warming spleen and stomach for dispelling cold, Back to Yang Tongmai, asarum relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping, fructus toosendan relax liver promoting the circulation of qi, analgesic,
Except damp and hot, expelling parasite, betel nut desinsection, disperse accumulations, promoting the circulation of qi, preventing malaria.Scientific compatibility, each component mutually act synergistically, anti-inflammatory analgetic, antibacterial
Detumescence, expelling wind and clearing away cold, clearing heat and detoxicating, benefit yang transforming qi, have the effect of splendid, for 1~3 years old to treatment mesenteric lymphadenitis
The cure rate of pediatric patient be up to 86%, total effective rate and be up to 100%, for more than 4 years old patient cure rate be up to 84%,
Total effective rate is up to 98%.And take safety.In addition, the Chinese medicine composition of the present invention can be made into a variety of formulations, to treatment intestines system
Film lymphnoditis is respectively provided with good effect, it is further preferred that, can meet the needs of different patients the effect of capsule.Sent out in addition through clinic
The effect of existing traditional Chinese medicine composition for treating roundworm disease of the present invention, is also excellent.
Embodiment
Following basis《Chinese Pharmacopoeia》、《Dictionary of medicinal plant》And《Chinese draft》Introduce the nature and flavor of primary raw material medicine, return
Through basic conditions such as, function and applications.
Dark plum:It is sour, puckery, put down.Return liver, spleen, lung, large intestine channel.Astringe the lung, puckery intestines, promote the production of body fluid, claming ascaris.For chronic cough of deficiency lung, chronic diarrhea
Protracted dysentery, abnormal heat are quenched one's thirst, ascariasis of biliary tract vomiting stomachache.
Corydalis tuber:It is pungent, bitter, temperature.Return liver, the spleen channel.Promoting blood circulation, promoting the circulation of qi, analgesic.For chest side of body, epigastric pain, chest impediment and cardialgia, warp
Close dysmenorrhoea, postpartum stasis, tumbling and swelling.
Root tuber of aromatic turmeric:It is pungent, bitter, tremble with fear.Return liver, the heart, lung channel.Promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral, clear away heart-fire cool blood, normalizing gallbladder to cure jaundice.For chest
Side of body shouting pain, chest impediment and cardialgia, closed dysmenorrhea, swollen breasts, pyreticosis coma, epilepsy are gone mad, blood-head tells nosebleed, jaundice.
Cooked aconite:Xin Gan, heat are poisonous.Enter the heart channel of Hang-Shaoyin, the spleen channel, kidney channel.Recuperating depleted yang, mends fire supporing yang, dispelling cold and removing dampness.Control the moon
Refusing yang is contained, loss of YANG due to profuse perspiration, profit is told and faints inverse, trusted subordinate's crymodynia, Spleen diarrhea cold dysentery, tinea pedis oedema infantile chronic fright, wind-cold-dampness arthralgia, Wei lame arrests
Contraction, impotence, Gong Leng is cloudy, the disease of the leakage of subcutaneous ulcer sore and all chronic diseaseses.
Cassia twig:Acrid, sweet, warm.The thoughts of returning home, lung, bladder warp.Sweating expelling pathogenic factors from muscles and skin, warming meridian, helps yang transforming qi, flat gas that spins.For
Anemofrigid cold, coldness and pain in the epigastrium, blood trembles with fear Amenorrhea, joint pain, phlegm and retained fluid, oedema, palpitaition, run quickly globefish.
Golden cypress:Hardship, tremble with fear.Return kidney, bladder warp.Heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment.For damp-heat dysentery, jaundice urine
Red, with lower pruritus vulvae, puckery pain of heat gonorrhea, tinea pedis impotence is knitted, hectic fever due to yin labor heat, night sweat, seminal emission, sore swollen toxin, eczema wet sore.
The coptis:Hardship, tremble with fear.The thoughts of returning home, spleen, stomach, liver, courage, large intestine channel.Heat-clearing and damp-drying drug, purging intense heat and detonicating.For damp and hot feeling of fullness, vomit
Acid regurgitation is told, rush down dysentery, jaundice, unconsciousness due to high fever, heart-fire hyperactivity, dysphoria and insomnia, palpitation and uneasiness, blood-head tells nosebleed, hot eyes, toothache, is quenched one's thirst,
Carbuncle swells treat sore；Eczema, wet sore are controlled outside, duct is suppurated.
Radix Angelicae Sinensis:Sweet, acrid, warm.Return liver, the heart, the spleen channel.Replenishing and activating blood, menstruction regulating and pain relieving, relax bowel.It is dizzy for blood deficiency chlorosis
Dizzy palpitaition, irregular menstruation, closed dysmenorrhea, asthenia cold abdominalgia, arthralgia pain due to rheumatism, injury from falling down, ulcer sores, dry constipation of intestines.
Pericarpium zanthoxyli:Pungent, temperature is slightly poisonous.Enter spleen, stomach, kidney channel.Warming spleen and stomach for dispelling cold, analgesic, eliminating dampness, desinsection.(1) stomach abdomen crymodynia is controlled,
Vomiting, rush down dysentery, wind-cold-dampness arthralgia, lung cold cough and asthma, colic, roundworm disease.(2) enterobiasis, decocting liquid bowel lavage are controlled；Under pruritus vulvae band, pernio is decocted
Washing；Dentalgia, vinegar, which is decocted to contain, to be gargled.
Rhizoma zingiberis:It is pungent, heat.Returns spleen, stomach, kidney, the heart, lung channel.Warming spleen and stomach for dispelling cold, Back to Yang Tongmai, Wenfei of drink.It is cold for gastral cavity abdomen
Bitterly, vomiting and diarrhea, cold weak pulse of limb, cold drink are breathed with cough.
Asarum:It is pungent, temperature.The thoughts of returning home, lung, kidney channel.Relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping is sensible, Wenfei of drink.For anemofrigid cold,
Headache, toothache, runny nose of having a stuffy nose, allergic rhinitis, nasosinusitis, arthralgia pain due to rheumatism, sputum cough.
Fructus toosendan:Hardship, tremble with fear.Enter liver, stomach, small intestinl channel.Easypro liver promoting qi circulation and relieving pain, except damp and hot, expelling parasite.It is swollen for chest side of body, gastral cavity abdomen
Bitterly, colic, abdominal pain due to enterositosis.
Betel nut:It is bitter, pungent, temperature.Return stomach, large intestine channel.Desinsection, disperse accumulations, promoting the circulation of qi, Li Shui, preventing malaria.For taeniasis, roundworm disease,
Fasciolopsiasis, abdominal pain due to enterositosis, stagnate rush down dysentery, tenesmus, oedema tinea pedis, malaria.
The specific embodiment of the present invention is described below, illustrated embodiment is served only for explaining the present invention, is not intended to
Limit the scope of the present invention.
Embodiment 1
A kind of Chinese medicine composition for treating mesenteric lymphadenitis, include the bulk drug of following weight：
It is dark plum 5g, corydalis tuber 10g, root tuber of aromatic turmeric 10g, cooked aconite 2g, cassia twig 5g, golden cypress 5g, coptis 2g, Radix Angelicae Sinensis 5g, pericarpium zanthoxyli 4g, dry
Ginger 4g, asarum 1.5g, fructus toosendan 10g, betel nut 10g.
Above-mentioned raw materials medicine according to a conventional method boil by decocting.
Embodiment 2
A kind of Chinese medicine composition for treating mesenteric lymphadenitis, include the bulk drug of following weight：
Dark plum 15g, corydalis tuber 20g, root tuber of aromatic turmeric 20g, cooked aconite 4g, cassia twig 15g, golden cypress 15g, coptis 4g, Radix Angelicae Sinensis 15g, pericarpium zanthoxyli
6g, rhizoma zingiberis 6g, asarum 2.5g, fructus toosendan 20g, betel nut 20g.
Above-mentioned raw materials medicine according to a conventional method boil by decocting.
Embodiment 3
A kind of Chinese medicine composition for treating mesenteric lymphadenitis, include the bulk drug of following weight：
Dark plum 8g, corydalis tuber 12g, root tuber of aromatic turmeric 12g, cooked aconite 2.5g, cassia twig 8g, golden cypress 8g, coptis 2.5g, Radix Angelicae Sinensis 8g, pericarpium zanthoxyli
4.5g, rhizoma zingiberis 4.5g, asarum 1.8g, fructus toosendan 12g, betel nut 12g.
Above-mentioned raw materials medicine according to a conventional method boil by decocting.
Embodiment 4
A kind of Chinese medicine composition for treating mesenteric lymphadenitis, include the bulk drug of following weight：
Dark plum 12g, corydalis tuber 18g, root tuber of aromatic turmeric 18g, cooked aconite 3.5g, cassia twig 12g, golden cypress 12g, coptis 3.5g, Radix Angelicae Sinensis 12g,
Pericarpium zanthoxyli 5.5g, rhizoma zingiberis 5.5g, asarum 2.2g, fructus toosendan 18g, betel nut 18g.
Above-mentioned raw materials medicine according to a conventional method boil by decocting.
Embodiment 5
A kind of Chinese medicine composition for treating mesenteric lymphadenitis, include the bulk drug of following weight：
Dark plum 10g, corydalis tuber 15g, root tuber of aromatic turmeric 10g, cooked aconite 2g, cassia twig 10g, golden cypress 10g, coptis 3g, Radix Angelicae Sinensis 10g, pericarpium zanthoxyli
5g, rhizoma zingiberis 5g, asarum 2g, fructus toosendan 10g, betel nut 10g.
Above-mentioned raw materials medicine according to a conventional method boil by decocting.
Embodiment 6
A kind of Chinese medicine composition for treating mesenteric lymphadenitis, include the bulk drug of following weight：
Dark plum 10g, corydalis tuber 15g, root tuber of aromatic turmeric 20g, cooked aconite 4g, cassia twig 10g, golden cypress 10g, coptis 3g, Radix Angelicae Sinensis 10g, pericarpium zanthoxyli
5g, rhizoma zingiberis 5g, asarum 2g, fructus toosendan 20g, betel nut 20g.
Above-mentioned raw materials medicine according to a conventional method boil by decocting.
Embodiment 7
A kind of Chinese medicine composition for treating mesenteric lymphadenitis, include the bulk drug of following weight：
Dark plum 10g, corydalis tuber 15g, root tuber of aromatic turmeric 15g, cooked aconite 3g, cassia twig 10g, golden cypress 10g, coptis 3g, Radix Angelicae Sinensis 10g, pericarpium zanthoxyli
5g, rhizoma zingiberis 5g, asarum 2g, fructus toosendan 15g, betel nut 15g.
Above-mentioned raw materials medicine according to a conventional method boil by decocting.
Embodiment 8
A kind of Chinese medicine composition for treating mesenteric lymphadenitis, include the bulk drug of following weight：
Dark plum 5g, corydalis tuber 7.5g, root tuber of aromatic turmeric 7.5g, cooked aconite 1.5g, cassia twig 5g, golden cypress 5g, coptis 1.5g, Radix Angelicae Sinensis 5g, river
Green pepper 2.5g, rhizoma zingiberis 2.5g, asarum 1g, fructus toosendan 7.5g, betel nut 7.5g.
Above-mentioned raw materials medicine according to a conventional method boil by decocting.
A kind of traditional Chinese medicine composition for treating mesenteric lymphadenitis for treating mesenteric lymphadenitis of the present invention has notable
Effect, in order to verify its advantage, by the present invention a kind of Chinese medicine composition for treating mesenteric lymphadenitis it is each
Embodiment is tested, and test method and result are as follows：
First, clinical data
1st, basic document：Mesenteric lymphadenitis patient 400 is collected altogether；1~test group of test group 8, every group 50.
Test group 1：This group 50,4~15 years old age 40,15~40 years old 10.
Test group 2：This group 50,4~15 years old age 40,15~40 years old 10.
Test group 3：This group 50,4~15 years old age 40,15~40 years old 10.
Test group 4：This group 50,4~15 years old age 40,15~40 years old 10.
Test group 5：This group 50,4~15 years old age 40,15~40 years old 10.
Test group 6：This group 50,4~15 years old age 40,15~40 years old 10.
Test group 7：This group 50,4~15 years old age 40,15~40 years old 10.
Test group 8：This group 50,1~3 years old age.
2nd, clinical manifestation：Often in upper respiratory tract infection symptoms such as 1~2 day sense general malaise of premorbid, pharyngalgia, heatings.After
And suffer from abdominal pain, more around left lower quadrant and navel, often in paroxysmal, such as coil buckling sample.Occurring pain after feed again can vomit
Tell food.To have a medical check-up and see flush, lip is pale, congestion of throat, and abdominal tenderness is distributed by bottom right to upper left in diagonal more, but with
Right Lower Abdomen is obvious, more without muscle tonue and Blumberg's sign.
3rd, Excluded cases：Other diseases such as appendicitis, lymphadenitis tuberculosa.
2nd, treatment method and the course for the treatment of
Test group 1：A kind of Chinese medicine composition (embodiment 1) for treating mesenteric lymphadenitis of the present invention, 1 dose of day, water
Decoct to divide 2 times and warmly take use, 7 days are 1 course for the treatment of, take 1~3 course for the treatment of.
Test group 2：A kind of Chinese medicine composition (embodiment 2) for treating mesenteric lymphadenitis of the present invention, 1 dose of day, water
Decoct to divide 2 times and warmly take use, 7 days are 1 course for the treatment of, take 1~3 course for the treatment of.
Test group 3：A kind of Chinese medicine composition (embodiment 3) for treating mesenteric lymphadenitis of the present invention, 1 dose of day, water
Decoct to divide 2 times and warmly take use, 7 days are 1 course for the treatment of, take 1~3 course for the treatment of.
Test group 4：A kind of Chinese medicine composition (embodiment 4) for treating mesenteric lymphadenitis of the present invention, 1 dose of day, water
Decoct to divide 2 times and warmly take use, 7 days are 1 course for the treatment of, take 1~3 course for the treatment of.
Test group 5：A kind of Chinese medicine composition (embodiment 5) for treating mesenteric lymphadenitis of the present invention, 1 dose of day, water
Decoct to divide 2 times and warmly take use, 7 days are 1 course for the treatment of, take 1~3 course for the treatment of.
Test group 6：A kind of Chinese medicine composition (embodiment 6) for treating mesenteric lymphadenitis of the present invention, 1 dose of day, water
Decoct to divide 2 times and warmly take use, 7 days are 1 course for the treatment of, take 1~3 course for the treatment of.
Test group 7：A kind of Chinese medicine composition (embodiment 7) for treating mesenteric lymphadenitis of the present invention, 1 dose of day, water
Decoct to divide 2 times and warmly take use, 7 days are 1 course for the treatment of, take 1~3 course for the treatment of.
Test group 8：A kind of Chinese medicine composition (embodiment 8) for treating mesenteric lymphadenitis of the present invention, 1 dose of day, water
Decoct to divide 2 times and warmly take use, 3 days are 1 course for the treatment of.Take 1~3 course for the treatment of.
3rd, treatment results
Curative effect judging standard：Cure：Stomachache and simultaneous disease disappear, and body temperature is normal, and belly color ultrasound shows that lymphonodi mesenterici is extensive
It is multiple normal.Effectively：Symptom mitigation or the disappearances such as stomachache, body temperature is normal, and belly color ultrasound shows that lymphonodi mesenterici reduces.It is invalid：
Colic symptoms improve less, and belly color ultrasound shows that mesenterium film lymph node is unchanged.Total effective=healing+effectively.Total effective rate
=(cure+effectively)/total number of cases.
1st, the case number of cases of the therapeutic effect of each test group is as shown in table 1 below：
| Case load (example) | Fully recover (example) | Effectively (example) | Invalid (example) | Total effective (example) | |
| Test group 1 | 50 | 36 | 8 | 6 | 44 |
| Test group 2 | 50 | 35 | 9 | 6 | 44 |
| Test group 3 | 50 | 38 | 7 | 5 | 45 |
| Test group 4 | 50 | 39 | 7 | 4 | 46 |
| Test group 5 | 50 | 41 | 6 | 3 | 47 |
| Test group 6 | 50 | 40 | 8 | 2 | 48 |
| Test group 7 | 50 | 42 | 7 | 1 | 49 |
| Test group 8 | 50 | 43 | 7 | 0 | 50 |
2nd, the case percentage of the therapeutic effect of each test group is as shown in table 2 below：
| Fully recover (%) | Effectively (%) | Invalid (%) | Total effective (%) | |
| Test group 1 | 72 | 16 | 12 | 88 |
| Test group 2 | 70 | 18 | 12 | 88 |
| Test group 3 | 76 | 14 | 10 | 90 |
| Test group 4 | 78 | 14 | 8 | 92 |
| Test group 5 | 82 | 12 | 6 | 94 |
| Test group 6 | 80 | 16 | 4 | 96 |
| Test group 7 | 84 | 14 | 2 | 98 |
| Test group 8 | 86 | 14 | 0 | 100 |
3rd, model case
1. money so-and-so, man 5 years old, after parent tells that cause on the 1st suffers from sense during patient assessment, with stomachache, in paroxysmal, with the right side
Based on the light tenderness of lower abdomen, no Blumberg's sign, through ultrasound diagnosis, mesenteric lymphadenitis is diagnosed as.Take drug therapy 1 of the present invention
After the course for the treatment of, colic symptoms are taken a turn for the better, and are fully recovered after taking 1 course for the treatment of again, and follow-up is discontinued over 3 months without recurrence.
2. Zhang, female 7 years old, after parent tells that cause on the 2nd suffers from sense during patient assessment, there is Right Lower Abdomen pain, in paroxysm
Property, abdomen is soft, there is light tenderness, no Blumberg's sign, through ultrasound diagnosis, is diagnosed as mesenteric lymphadenitis.Take drug therapy 1 of the present invention
After the individual course for the treatment of, colic symptoms are taken a turn for the better, and are fully recovered after taking 1 course for the treatment of again, and follow-up is discontinued over the past half year without recurrence.
3. Lin, man 14 years old, after parent tells that cause on the 2nd suffers from sense during patient assessment, there is Right Lower Abdomen and navel week pain, be in
Paroxysmal, such as coil buckling sample, abdomen is soft, has light tenderness, no Blumberg's sign, through ultrasound diagnosis, is diagnosed as mesenteric lymphadenitis.Take this
After 1 course for the treatment of of invention drug therapy, colic symptoms take a turn for the better, and are fully recovered after taking 1 course for the treatment of again, continue to take 1 course for the treatment of consolidation afterwards
Curative effect, follow-up are discontinued over the past half year without recurrence.
4th, adverse reaction is observed
In Ureteral Calculus case, adverse reaction patient is found no, shows that one kind of the present invention treats mesenteric lymph
It is safe and reliable to tie scorching Chinese medicine composition.
Shown by above-mentioned clinical test, Chinese medicine composition of the present invention is to treatment mesenteric lymphadenitis patient tool
There is the effect of splendid, be up to 86%, total effective rate for the cure rate of the pediatric patient of 1~3 years old and be up to 100%, suffer within more than 4 years old
The cure rate of person is up to 84%, total effective rate and is up to 98%.Wherein, test group 3~4 is better than the therapeutic effect of test group 1~2,
Show that embodiment 3~4 is more preferable compared to the effect of 1~2 pair for the treatment of mesenteric lymphadenitis of embodiment；And test group 7 is than test group 3
~4 therapeutic effect is more preferable, it is known that compared to embodiment 1~4, embodiment 7 is optimal to the effect for treating mesenteric lymphadenitis
, the weight ratio of each component of embodiment 7 is most preferred so that each component synergy is optimal.In addition, test group 7 is than experiment
Group 5~6 therapeutic effect it is good, show embodiment 7 compared to each component of embodiment 5~6 synergy more preferably, show component root tuber of aromatic turmeric,
Cooked aconite, river, betel nut have large effect to curative effect；Test group 5 is better than the therapeutic effect of test group 1, i.e., embodiment 5 is compared
The effect of embodiment 1, more preferably the effect of test group 6 is better than the therapeutic effect of test group 2, i.e., embodiment 6 compares embodiment 2, was more
It is good, show that component dark plum, corydalis tuber, cassia twig, golden cypress, the coptis, Radix Angelicae Sinensis, pericarpium zanthoxyli, rhizoma zingiberis, asarum have large effect to curative effect.Separately
Outside, embodiment 8 is relative is reduced, special to supply young children and take, therapeutic effect it is further preferred that.To sum up, embodiment 7 to treatment 4 years old with
The effect of dorsal mesentery lymphnoditis patient, is more excellent, while embodiment 8 has extraordinary treatment to the patient for the treatment of less than 4 years old
Effect.Illustrate a kind of Chinese medicine composition for treating mesenteric lymphadenitis provided by the invention, each component mutually acts synergistically, to controlling
Treating mesenteric lymphadenitis has significant curative effect, and safe, has no toxic side effect.
In a further embodiment, a kind of Chinese medicine composition for treating mesenteric lymphadenitis of the invention passes through conventional side
Method is prepared into granule, oral liquid, pill, capsule, and treatment mesenteric lymphadenitis is respectively provided with good effect, especially capsule
The effect of agent, is more preferably.
Other inventor also has found the Chinese medicine composition of the treatment mesenteric lymphadenitis to treatment by clinical case
Roundworm disease also has good effect.Roundworm disease is due to that roundworm parasitizes enteron aisle, and with paroxysm navel pain abdomen pain, recurrent exerbation is
The parasitic disease of main clinical manifestation.78 roundworm patients are collected altogether.Its diagnosis basis, administrated method, the course for the treatment of, treatment standard
And clinical effectiveness is as follows：
Diagnosis basis：1. paroxysmal navel week stomachache, often breaks out suddenly, lead to without fixed place, can voluntarily alleviate.2. there can be heating cough
Cough or wheal group occur in asthma, blood-stained sputum, skin, kind of sleeping is ground one's teeth in sleep, and is salivated, rhiocnesmus.Sick lean and haggard long, look irritated,
Reject roundworm or discharge roundworm.3. the visible blue class of sclera, there is white pityriasis simplex in face, has the granular dot of white chestnut on the inside of lip, refers to
First piebald.The accessible streak roundworm group of belly, when it is poly- when dissipate.4. unhygienic diet and the vomiting of ascaris, row's ascarid history.5. microscopy of defecating is visible
Roundworm egg, acidophic cell can increase.6. it may occur in which the complication such as ascarid of biliary tract, ascaris intestinal obstruction.
Administrated method and the course for the treatment of are：A kind of Chinese medicine composition (embodiment 7) for treating mesenteric lymphadenitis of the present invention,
1 dose of day, decocting, which divides 2 times, warmly takes use, and 7 days are 1 course for the treatment of, take 1~3 course for the treatment of.
Diagnoses and treatment standard：Cure：Symptom disappears, and microscopy worm's ovum is repeatedly negative, and blood routine examination is normal.Take a turn for the better：Symptom
There is improvement, microscopy worm's ovum is not turned out cloudy.It is invalid：Symptom is unchanged, and microscopy worm's ovum is positive.Total effective=(recovery from illness+improvement), it is total effective
Rate=(recovery from illness+improvement)/total number of cases * 100%.
It is as shown in table 3 below for the case number of cases of roundworm disease patient outcomes：
It is as shown in table 4 below for the case percentage of roundworm disease therapeutic effect：
| Case type | Cure (%) | Take a turn for the better (%) | Invalid (%) | Total effective (%) |
| Roundworm disease | 82 | 10 | 8 | 92 |
Roundworm disease model case：
1. Chen, female 8 years old.After 1 day cause of private prosecution eats pungent raw and cold food during patient assessment, that night dashes forward in sleep
So there is right upper quadrant of the abdomen pain, bore top pain in paroxysmal, and back part diffuses to the right.Simultaneously with Nausea and vomiting, tell as in stomach
Tolerant and misery.When stop when sending out, it is toss about and feel uneasy during breaking-out, sweat all over, peripheral coldness.Take 1 treatment of drug therapy of the present invention
Cheng Hou, stomachache take a turn for the better, and the symptom such as Nausea and vomiting disappears, and is fully recovered after taking 1 course for the treatment of again, continue to take 1 course for the treatment of consolidation treatment afterwards
Effect, follow-up are discontinued over the past half year without recurrence.
2. Mr. Wang, male 12 years old.3 days causes of private prosecution and classmate have a dinner party after edible spicy hot chafing dish and cold drink during patient assessment, when
There is right upper quadrant of the abdomen pain suddenly in evening, and top is bored bitterly in paroxysmal, and back part diffuses to the right, when stop when sending out, while with night
Grind one's teeth in sleep, Nausea and vomiting, tell as gastric content and misery.After taking 1 course for the treatment of of drug therapy of the present invention, stomachache takes a turn for the better, nausea,
The symptoms such as vomiting are disappeared, and are fully recovered after taking 1 course for the treatment of again, and follow-up is discontinued over 3 months without recurrence.
3. Zhang, man 14 years old.After 3 days causes of private prosecution eat a large amount of barbecues and cold drink during patient assessment, there is the right side suddenly in that night
Upper abdomen and navel week pain, top pain is bored in paroxysmal, and back part diffuses to the right, when when sending out only simultaneously with Nausea and vomiting, tell
For gastric content and misery.After taking 1 course for the treatment of of drug therapy of the present invention, stomachache takes a turn for the better, and the symptom such as Nausea and vomiting disappears, again
Fully recovered after taking 1 course for the treatment of, follow-up is discontinued over the past half year without recurrence.
Shown by clinical test, a kind of Chinese medicine composition for treating mesenteric lymphadenitis provided by the invention, treated
The cure rate of roundworm disease is 82%, total effective rate 92%, it is seen that Chinese medicine composition provided by the invention is to treating roundworm disease
With it is preferable the effect of.
In summary, a kind of Chinese medicine composition for treating mesenteric lymphadenitis provided by the present invention, dark plum is held back in side
Lung, puckery intestines, claming ascaris, corydalis tuber promoting blood circulation, promoting the circulation of qi, analgesic, root tuber of aromatic turmeric promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral, the cool blood that clears away heart-fire, normalizing gallbladder to cure jaundice are ripe attached
Sub- mends fire supporing yang, dispelling cold and removing dampness, cassia twig warming meridian, helps yang transforming qi, flat gas that spins, golden cypress heat-clearing and damp-drying drug, purging intense heat, except steaming, solution
Poison, coptis heat-clearing and damp-drying drug, purging intense heat and detonicating, Chinese angelica blood supplementing are invigorated blood circulation, relieve pain, relaxed bowel, and pericarpium zanthoxyli warming spleen and stomach for dispelling cold, analgesic, eliminating dampness, are killed
Worm, rhizoma zingiberis warming spleen and stomach for dispelling cold, Back to Yang Tongmai, asarum relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping, fructus toosendan relax liver promoting the circulation of qi, analgesic, except damp and hot, drive
Worm, betel nut desinsection, disperse accumulations, promoting the circulation of qi, preventing malaria.Scientific compatibility, each component mutually act synergistically, anti-inflammatory analgetic, antibacterial detumescence, wind-dispelling
Cold dispelling, clearing heat and detoxicating, benefit yang transforming qi, have the effect of splendid, for the patient's of 1~3 years old to treatment mesenteric lymphadenitis
Cure rate is up to 86%, total effective rate and is up to 100%, is up to 84%, total effective rate for the cure rate of more than 4 years old patient and is up to
98%.And take safety.In addition, the Chinese medicine composition of the present invention can be made into a variety of formulations, it is equal to treatment mesenteric lymphadenitis
With good effect, it is further preferred that, can meet the needs of different patients the effect of capsule.It is of the present invention through clinical discovery in addition
Traditional Chinese medicine composition for treating roundworm disease the effect of it is also excellent.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
God any modification, equivalent substitution and improvements done etc., should be included within the scope of protection of the invention with principle.
Claims (6)
1. a kind of Chinese medicine composition for treating mesenteric lymphadenitis, it is characterised in that be made up of the bulk drug of following parts by weight：
50 ~ 150 parts of dark plum, 100 ~ 200 parts of corydalis tuber, 100 ~ 200 parts of root tuber of aromatic turmeric, 20 ~ 40 parts of cooked aconite, 50 ~ 150 parts of cassia twig, golden cypress 50 ~
150 parts, 20 ~ 40 parts of the coptis, 50 ~ 150 parts of Radix Angelicae Sinensis, 40 ~ 60 parts of pericarpium zanthoxyli, 40 ~ 60 parts of rhizoma zingiberis, 15 ~ 25 parts of asarum, fructus toosendan 100 ~
200 parts, 100 ~ 200 parts of betel nut.
2. a kind of Chinese medicine composition for treating mesenteric lymphadenitis according to claim 1, it is characterised in that by following
The bulk drug composition of parts by weight：80 ~ 120 parts of dark plum, 120 ~ 180 parts of corydalis tuber, 120 ~ 180 parts of root tuber of aromatic turmeric, 25 ~ 35 parts of cooked aconite, osmanthus
80 ~ 120 parts of branch, 80 ~ 120 parts of golden cypress, 25 ~ 35 parts of the coptis, 80 ~ 120 parts of Radix Angelicae Sinensis, 45 ~ 55 parts of pericarpium zanthoxyli, 45 ~ 55 parts of rhizoma zingiberis, asarum
18 ~ 22 parts, 120 ~ 180 parts of fructus toosendan, 120 ~ 180 parts of betel nut.
3. a kind of Chinese medicine composition for treating mesenteric lymphadenitis according to claim 1, it is characterised in that by following
The bulk drug composition of parts by weight：100 parts of dark plum, 150 parts of corydalis tuber, 150 parts of root tuber of aromatic turmeric, 30 parts of cooked aconite, 100 parts of cassia twig, golden cypress 100
Part, 30 parts of the coptis, 100 parts of Radix Angelicae Sinensis, 50 parts of pericarpium zanthoxyli, 50 parts of rhizoma zingiberis, 20 parts of asarum, 150 parts of fructus toosendan, 150 parts of betel nut.
4. a kind of Chinese medicinal composition preparation for treating mesenteric lymphadenitis, it is characterised in that by any one of claim 1 ~ 3 institute
The Chinese medicine composition for the treatment mesenteric lymphadenitis stated is made, the Chinese medicinal composition preparation of the treatment mesenteric lymphadenitis
For granule, oral liquid, pill, capsule one kind.
5. the Chinese medicine composition of the treatment mesenteric lymphadenitis described in any one of claim 1 ~ 3 is preparing treatment mesenterium leaching
Fawn on the application in the medicine of inflammation.
6. the Chinese medicine composition of the treatment mesenteric lymphadenitis described in any one of claim 1 ~ 3 is preparing treatment roundworm disease
Application in medicine.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101168038A (en) * | 2007-09-29 | 2008-04-30 | 罗华祥 | Traditional Chinese medicine for treating biliary ascariasis |
| CN102309737A (en) * | 2010-07-01 | 2012-01-11 | 李青 | Traditional Chinese medicine pill for relieving colic caused by ascaris and alleviating pain |
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2016
- 2016-08-30 CN CN201610768890.XA patent/CN106267077B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101168038A (en) * | 2007-09-29 | 2008-04-30 | 罗华祥 | Traditional Chinese medicine for treating biliary ascariasis |
| CN102309737A (en) * | 2010-07-01 | 2012-01-11 | 李青 | Traditional Chinese medicine pill for relieving colic caused by ascaris and alleviating pain |
Non-Patent Citations (1)
| Title |
|---|
| 乌梅汤治疗小儿肠系膜淋巴结炎47例临床观察;薛付春等;《中医临床研究》;20141231;第6卷(第4期);第113-114页 * |
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