CN106244371A - A kind of blood sugar lowering Rhizoma Polygonati grape health care wine and production technology thereof - Google Patents
A kind of blood sugar lowering Rhizoma Polygonati grape health care wine and production technology thereof Download PDFInfo
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- CN106244371A CN106244371A CN201610619543.0A CN201610619543A CN106244371A CN 106244371 A CN106244371 A CN 106244371A CN 201610619543 A CN201610619543 A CN 201610619543A CN 106244371 A CN106244371 A CN 106244371A
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- Prior art keywords
- vitis viniferae
- fructus vitis
- rhizoma polygonati
- wine
- fructus
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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- Chemical & Material Sciences (AREA)
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Abstract
The present invention provides a kind of blood sugar lowering Rhizoma Polygonati grape health care wine and production technology thereof.Fructus Vitis viniferae is obtained Fructus Vitis viniferae wine liquid through fermentation for the first time: cleaned by Fructus Vitis viniferae after drying up or drying, destemming broken；Pump into fermentation tank, add yeast, temperature control 18 28 DEG C, ferment 6 10 days；When pol reaches 8 10g/L, carry out skin slag separation, obtain Fructus Vitis viniferae wine liquid.In the Fructus Vitis viniferae wine liquid that first time ferments, it is proportionally added into the Chinese medicinal components such as the Rhizoma Polygonati powder, powder of Radix Puerariae and the Fructus Mume that crush, is circulated entrance second time fermentation immediately；Once circulating every 8 hours, temperature controls in the range of 18 28 DEG C later；Circulation 30 40 minutes every time, when pol is less than 4g/L, stop circulation；Quiet fermentation under the room temperature of 68 weeks again, treats that malic acid transfers lactic acid, fermentation ends completely to.The wine pure natural that the inventive method prepares, without adding, has reduction blood glucose, the feature of regulation blood sugar for human body balance, thoroughly meets diabetes Man's Demands, and blood sugar decreasing effect is good.
Description
Technical field
The present invention relates to a kind of blood sugar lowering Rhizoma Polygonati grape health care wine and production technology thereof, belong to technical field of health care food.
Background technology
Wine is the brewed wine of a kind of low wine degree, and with a long history, local flavor is delicious, nutritious, high character, deeply by people
Like.Contained pectic substance, phlegmatic temperament and various organic acid can regulate human metabolism function；Contained mineral (includes trace
Element) and multivitamin, the physiological function of human body can be regulated；Contained glucose, fructose and several amino acids, can direct quilt
Absorption of human body；So, the health care of wine is the most extremely paid close attention in the whole world.Modern medicine proves, it is tired that wine has recovery
Labor, blood circulation promoting, reduction hypertension, reduce blood glucose, prevention coronary heart disease, atherosclerosis, appetite stimulator, help digest
Effect with beauty treatment.The active component resveratrol contained in red wine has anti-angiocardiopathy and anticancer effect, institute
With the brew of, wine with drink the attention being increasingly subject to people.
Although the health care of wine is more complete, but the most mediocre, and individual event function does not highlight, and effect is failed to understand
Aobvious, as what crowd drinks, lack directivity, specific aim, so, it is drunk by people as common low wine degree beverage
With.The most not for suffering from the wine that diabetic population is developed.According to media report, China patient of diabetes
Person nearly 100,000,000 more than, occupies first of the world, and the health diet of these groups of people merits attention.So, " should drink for solving these groups of people
Wine, healthy again " requirement, need research and development to have the grape health care wine of special health-care effect.
Current existing grape health care wine, is not for diabetes patient's research and development, and there is certain weak point.Example
As, the patent of invention of patent No. ZL201410321385.1, disclose a kind of grape brandy health preserving wine, with grape brandy be
Wine base, by weight: Cortex Cinnamomi 2-7%, Fructus Rubi 2-7%, Fructus Lycii 3-10%, Rhizoma Polygonati 2-5%, Radix Puerariae 1-3%, Herba Cistanches 1-
5%, surplus is grape brandy, and using static state low temperature soak technology described six kinds of health care food materials to be brewageed into alcoholic strength is 42-
The grape brandy health preserving wine of 48 degree.There is health invigorating, the effect called forth one's youthful vigor.Its preparation method is, first that Fructus Vitis viniferae is former
Material fermentation is prepared as the grape brandy that alcoholic strength is 42-48 degree.Then by Cortex Cinnamomi 2-7%, Fructus Rubi 2-7%, Chinese holly under room temperature
It is individual month of 2-10 in wine base that Fructus Lycii 3-10%, Rhizoma Polygonati 2-5%, Radix Puerariae 1-3%, Herba Cistanches 1-5% are immersed in grape brandy.So
And, this patent use low temperature soak technology, six kinds health care food materials effective ingredient can not effectively obtain, and directly immersion after shadow
Ring the mouthfeel of grape brandy.For another example, a kind of of application number 201510472735.9 has the Calyx seu fructus physalis Fructus Vitis viniferae improving three-hypers effect
Low-degree health care liquor and preparation method, including following parts by weight of component: Calyx seu fructus physalis fruit 30～50, Fructus Vitis viniferae 200～250, tea polyphenols 5～
7, Fructus Phyllanthi fruit 10～12, Fructus Momordicae 8～14, Rhizoma Polygonati Odorati lixiviating solution 6～8, polygonatum sibiricum red juice 8～10, Radix Puerariae lixiviating solution 3～5, richness
The trichoderma reesei 2～4 of activity containing beta-glucosidase, saccharomyces cerevisiae high activity dried yeast powder 3～5, pectase 2～3, yeast
Polysaccharide 3～5, Raffinose 8～10, succinic acid 6～10, alditol 3～6, caramel dimethyl phthalate 4～7, chitosan 2～3, sulfurous acid
Sodium 1～2, Bentonite porous material 2.3～2.7, polyvinylpyrrolidone 2.4～2.6, appropriate water, form through brew.This health care
Liquor raw material composition is various, and containing more additive.It it not pure natural health-care wine.
Summary of the invention
Present invention aims to the deficiencies in the prior art, it is provided that a kind of blood sugar lowering Rhizoma Polygonati grape health care wine and life thereof
Production. art, the wine pure natural that the method prepares, without adding, there is reduction blood glucose, regulate the feature of blood sugar for human body balance, thorough
The end, meets diabetes Man's Demands, and blood sugar decreasing effect is good.
The technical scheme is that a kind of blood sugar lowering Rhizoma Polygonati grape health care wine, Fructus Vitis viniferae is obtained through fermentation for the first time
Fructus Vitis viniferae wine liquid, is subsequently adding Chinese medicinal components and carries out preparing after second time is fermented；Described Chinese medicinal components can be to have blood sugar lowering to make
Chinese crude drug, such as Rhizoma Polygonati, Radix Puerariae, Fructus Mume.Wherein, every liter of Fructus Vitis viniferae wine liquid adds 8 grams of Rhizoma Polygonati powder, powder of Radix Puerariae 4 grams, Fructus Mume 2 grams.
Described first time ferments: first Fructus Vitis viniferae is used clean water one time, then uses pure water cleaning showers, dry up or dry
After, destemming broken；Broken Fructus Vitis viniferae is pumped into fermentation tank, adds yeast, make Fructus Vitis viniferae enter fermentation phase, temperature control 18 28 as early as possible
DEG C, ferment 6 10 days；When pol reaches 8-10g/L, carry out skin slag separation, obtain Fructus Vitis viniferae wine liquid.
Described second time is fermented: be proportionally added into the Chinese medicinal components crushed in the Fructus Vitis viniferae wine liquid that first time ferments:
Rhizoma Polygonati powder, powder of Radix Puerariae and Fructus Mume etc., be circulated so that it is uniformly merge with Fructus Vitis viniferae wine liquid immediately；Carried out one every 8 hours later
Secondary circulation, temperature controls in the range of 18 28 DEG C；Circulation 30 40 minutes every time, when pol is less than 4g/L, stop following
Ring；Quiet fermentation under the room temperature of 68 weeks again, treats that malic acid transfers lactic acid, fermentation ends completely to.
Concrete, the production technology of blood sugar lowering Rhizoma Polygonati grape health care wine of the present invention, step is as follows:
(1) raw material prepares: first by Fructus Vitis viniferae clean water one time, then use pure water cleaning showers, after drying up or drying,
Destemming broken.Seed of Fructus Vitis viniferae can not be injured time broken, but guarantee to scratch Pericarpium Vitis viniferae.Chinese medicinal components is gone the removal of impurity, pulverizes standby
With.
(2) ferment wine brewing
The brew of blood sugar lowering Rhizoma Polygonati grape health care wine is in two stages, it may be assumed that fermentation for the first time and second time fermentation.
Fermentation for the first time: i.e. grape fermentation.Broken Fructus Vitis viniferae is pumped into fermentation tank, adds yeast, make Fructus Vitis viniferae enter as early as possible
Enter the fermentation phase, in the range of temperature control 18 28 DEG C, ferment 6 10 days.When pol reaches 8-10g/L, carry out skin slag separation,
Obtain Fructus Vitis viniferae wine liquid, proceed to second time and ferment.
Second time fermentation: the Fructus Vitis viniferae wine liquid fermented for the first time is added the Chinese medicinal components crushed, is circulated immediately,
Chinese medicinal components is made fully uniformly to merge with Fructus Vitis viniferae wine liquid；Once circulating every 8 hours, temperature controls at 18 28 DEG C later
In the range of.Circulation 30 40 minutes every time, when pol is less than 4g/L, stop circulation.Under the room temperature of 68 weeks quiet again
Ferment, treats that malic acid transfers lactic acid completely to.I.e. fermentation ends.
Then storage aging was no less than 24 months, filtration, fill.
Blood sugar lowering Rhizoma Polygonati grape health care wine of the present invention has significant blood sugar reducing function, it is impossible to the indiscriminate drink of carousing, the most often drinks
Blood sugar for human body can be made to balance, drink at about 100-150ml every time, every day, the amount of drinking was advisable less than 400ml.
Blood sugar lowering Rhizoma Polygonati grape health care wine of the present invention, is to brewage with Fructus Vitis viniferae, Rhizoma Polygonati, Radix Puerariae, Fructus Mume etc. for raw material is fermented
Form, be pure brewed wine, containing the beneficiating ingredient of multiple beneficial health, wherein:
Fructus Vitis viniferae: use the black purple special Fructus Vitis viniferae of wine brewing, such as Cabernet Sauvignon, Cabernet franc, Mei Le etc..Fructus Vitis viniferae contains abundant cyanine
Element, polyphenols, resveratrol, containing abundant aminoacid, protein, vitamin B1, B2, B6, C, P and carotene etc.
Nutritional labeling, containing mineral necessary to a large amount of human bodies, as calcium, phosphorus, potassium, selenium, the trace element such as zinc, have the strongest
Antioxidant activity.Wine is the most healthy beverage, and it can regulate human metabolism, blood circulation promoting, prevent cholesterol
Increase, diuresis can also be played simultaneously, excite liver function and prevent the effect of aging.Long-term drink can prevent vitamin C deficiency, reduce blood
Fat, vessel softening, facilitating digestion.
Rhizoma Polygonati: Compendium of Material Medica records Rhizoma Polygonati: sweet, flat, nontoxic.Invigorating the spleen and replenishing QI, except rheumatism, settling five organs.Clothes are made light of one's life by commiting suicide and are prolonged for a long time
Year is the most hungry.Mend five kinds of strain and seven kinds of impairment, help muscles and bones, resistance to cold and summer-heat, strengthening the spleen stomach, moisten cardiopulmonary.Claim it to obtain the essence of female soil, obtain the pure essence in the world.
Modern medicine study finds, Rhizoma Polygonati contains abundant polygonatum polysaccharide, oligosaccharide, nicotinic acid, lymphatic temperament, aminoacid and zinc, copper, ferrum etc.
The trace element of multiple needed by human, can strengthen cardiac contractile force, increases coronary flow, improves lectin from hemolymph parameter and tremulous pulse medicated porridge sample
Hardening focus.There is kidney tonifying, boosting qi and nourishing yin, spleen invigorating, lung moistening, boosting qi and nourishing yin, lung moistening, the function such as blood sugar lowering, blood fat reducing, blood pressure lowering.For
Treatment weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat such as is quenched one's thirst the disease.Polygonatum polysaccharide is on kidney
Blood glucose that gland causes is too high obvious reduction effect, is the main active of suppression blood glucose regulation blood glucose, to a-glucose
Glycosides enzyme has the strongest inhibitory action, thus delays disaccharidase to be decomposed into the time of monosaccharide under a-glucosidase effect, balance
The infiltration rate of the monosaccharide such as glucose, fructose, reduces the purpose of blood glucose after the meal.The postprandial hyperglycemia of persistence, can
Causing multiple physical function Developmental and Metabolic Disorder and vascular lesion, cause generation and the deterioration of complication, pancreatic function also will enter simultaneously
Suffering damage of one step.Rhizoma Polygonati both tonifying spleen-yins, strengthening the spleen gas again, medicine-food two-purpose, is natural hypoglycemic medicine.
Radix Puerariae: Compendium of Material Medica records Radix Puerariae: property is sweet, pungent, flat, nontoxic.Cure mainly: quench one's thirst, high fever of the body, vomiting, all frauds, rise
Cloudy gas, solves all poison.Radix Puerariae recorded by Chinese medicine voluminous dictionary: [nature and flavor] are sweet, pungent, cool.[return through] returns spleen, stomach warp.[function cures mainly] expelling pathogenic factors from muscles
Bring down a fever, promote the production of body fluid, rash, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, let out
Rush down；Hypertension neck pain.Modern medicine study, Radix Puerariae contains abundant isoflavonoid, such as puerarin, daidzein
The nutritional labelings such as glycosides, Semen arachidis hypogaeae element, also trace element necessary to more than the ten kind of human body such as calcium, selenium, ferrum, copper, phosphorus, potassium, there is solution
Table is brought down a fever, promoting the production of body fluid to quench thirst, and the function of whetting the appetite is all-ages famous and precious tonic, has the good reputation of " Radix Ginseng in thousand ".Have
Significantly reduce blood glucose, blood fat reducing, the effect of reduction serum cholesterol, blood sugar recovery can be rapidly promoted normal.Contained by Radix Puerariae different
This material of flavone compound is a kind of natural phytohormone, and the endocrine of human body can be adjusted by it, cardiac nutrition, expands
Open blood vessel, improve the oxygen metabolism of cardiac muscle, improve microcirculation, reduce vascular resistance, make blood flow increase, therefore available cardiac muscle of preventing and treating lacks
Blood, myocardial infarction, arrhythmia, hypertension, the disease such as arteriosclerosis.
Fructus Mume: it is sour, puckery that " Chinese Pharmacopoeia " carries record [nature and flavor] is flat.[return through] returns liver, spleen, lung, large intestine channel.[function cures mainly]
Astringe the lung, astringing intestine to stop diarrhea, promote the production of body fluid, relieving colic caused by ascaris.For chronic cough of deficiency lung, chronic dysentery laxation, deficiency-heat quenches one's thirst, ascariasis of biliary tract vomiting stomachache, ascariasis of biliary tract.Existing
For medical research, Fructus Mume contains citric acid, and malic acid, succinic acid, saccharide compound, paddy stays the compositions such as alcohol, promoting the production of body fluid to quench thirst, is commonly used to
Treat quenching one's thirst and the disease such as calentura is thirsty, dry pharynx of polydipsia as thirsty in diabetics.
Blood sugar lowering Rhizoma Polygonati grape health care wine of the present invention, in addition to having the nutritional labeling of general wine, adds in wine
Polygonatum polysaccharide, the sugar-lowering components such as polyphenols, Radix Puerariae isoflavone, puerarin, organic acid, can effectively draw up and regulate people
Body blood glucose, is greatly improved the function of reducing blood sugar of wine, improves the directivity of the function of wine.Meanwhile, Portugal is added
Trace element necessary to the multiple human body such as aminoacid, protein, vitamin and calcium, selenium, ferrum, copper, phosphorus, potassium in grape wine.
The blood sugar lowering Rhizoma Polygonati grape health care wine of the present invention, rubbing up and interacting of plurality of active ingredients, enhance Fructus Vitis viniferae
The blood sugar lowering element of wine, regulates spleen, stomach, the function of kidney, and nutritious cardiac muscle, expands blood vessel, improves microcirculation, blood pressure lowering, fall
The effects such as fat, cholesterol reducing, softening cardiovascular and cerebrovascular vessel, invigorating the spleen and replenishing QI, nourishing YIN for benefiting the kidney, life prolonging.Myocardial ischemia can be prevented and treated, cardiac muscle
Infarction, blood glucose complication, hypertension, the disease such as hyperlipidemia, arteriosclerosis.
It is added as needed on different Chinese medicinal components, as having the Japanese raisintree fruit of hypoglycemic activity, Rhizoma Polygonati Odorati, Fructus Hippophae, Fructus Mori, the heart of a lotus seed
Semen Coicis etc.；There is the Fructus Crataegi of effect for reducing blood fat；There is the Flos Chrysanthemi of hypotensive activity；The Flos Lonicerae of heat-clearing and toxic substances removing；Mind tranquilizing and the heart calming
Semen Ziziphi Spinosae；The Chinese crude drug of the medicine-food two-purposes such as the Fructus Lycii of nourishing kidney-YIN, Rhizoma Dioscoreae, Arillus Longan, the grape health of available different efficacies
Wine.Preparation method, with as aforementioned, adds in second time fermentation, can be prepared as having blood sugar lowering and/or blood fat reducing, by blood
The grape health care wine of the effects such as pressure, enriching yin and nourishing kidney.
The present invention all innovates on raw material and technique:
1, raw material innovation
(1) vinifera is selected there is special requirement.Must be the Fructus Vitis viniferae age of tree more than 10 years, plant is healthy, fringe
Big Maturity is good, and pol reaches more than 200g/L, the most overhead the Fructus Vitis viniferae of about 60 centimeters.Because the biggest Fructus Vitis viniferae of the age of tree
Nutrient substance is the abundantest, and plant health Fructus Vitis viniferae miscellaneous bacteria infection rate is little, and pol is high.
(2) in wine production, increase the Chinese medicine of the integration of edible and medicinal herbs such as Rhizoma Polygonati, Radix Puerariae, Fructus Mume newly.Polygonatum polysaccharide, is suppression blood
The main active of sugar regulation blood glucose, has the strongest inhibitory action to human body a-glucosidase, thus has delayed disaccharidase
Under a-glucosidase effect, it is decomposed into the time of monosaccharide, slows down the human body infiltration rate to the monosaccharide such as glucose, fructose,
And then reduce the purpose with balance blood sugar.This material of Radix Puerariae isoflavone compounds is a kind of natural phytohormone, energy
Promote that the fast quick-recovery of post-prandial glycemia is normal, and there is the endocrine to human body be adjusted that cardiac nutrition is expanded blood vessel, promoted the production of body fluid
The effect quenched the thirst.Fructus Mume organic acid can exciting salivary secretion, promoting the production of body fluid to quench thirst, to eliminate the thirsty polydipsia of diabetics, calentura mouth
Yearningly, the disease such as dry pharynx has good mitigation.Through fermenting twice, Fructus Vitis viniferae, Rhizoma Polygonati, Radix Puerariae, Fructus Mume plurality of active ingredients are entered
Extraction of having gone rubs up, and adds the medicinal blood sugar reducing component of wine, makes Rhizoma Polygonati wine be provided with regulation spleen, stomach, the merit of kidney
Can be with significant effect of lowering blood sugar.
2, process innovation
(1) physical method control miscellaneous bacteria removal of impurity technique is used.In the pretreatment process of Fructus Vitis viniferae, traditional way is simply gone
Falling the foreign material that grape ear is carried secretly, do not clean, controlling miscellaneous bacteria is to add chemical preservative sulfur dioxide after Grape fragmentation i.e.
Chemical Control.The present invention, on the basis of first time clear water washs, adds again the spray washing of purified water, utilizes purified water
Absorption and reproducibility, the miscellaneous bacteria on physical removal grape berry surface and impurity, be fully achieved instant standard, to reach physical control
The purpose of miscellaneous bacteria.
(2) in fermentation for the first time, grape fermentation is used to shift to an earlier date skin slag separating technology.General wine is when fermentation, sugared
Degree reaches about 5g/L and carries out skin slag separation, i.e. alcohol fermentation terminates.This technique just carries out skin slag about pol 10g/L and divides
From, to increase the Chinese medicinal components effective ingredient precipitations such as the activity of second time fermentation, beneficially Rhizoma Polygonati, Radix Puerariae, Fructus Mume.
(3) in second time fermentation, delayed separating technology is used.I.e. add second time fermentation time, make Fructus Vitis viniferae wine liquid
To Rhizoma Polygonati, Radix Puerariae, Fructus Mume etc., Chinese medicinal components effective ingredient is fully hydrolyzed, water carries and alcohol extraction, makes effective ingredient separate out completely,
Ensure that effect of Rhizoma Polygonati wine.During ferment in second time, can constantly produce heat and carbon dioxide, utilize two
Carbonoxide take taking property, make volatile material in the Chinese medicinal components such as Rhizoma Polygonati, Radix Puerariae, Fructus Mume constantly volatilize, dispelling abnormal flavor, make wine body
Mouthfeel is purer；Contained sugar, starch are constantly degraded under saccharomycetic effect, generate ethanol, add the alcohol thickness of wine body；
Under temperature, water and alcohol function, the sugar-lowering components in the Chinese medicinal components such as Rhizoma Polygonati, Radix Puerariae, Fructus Mume constantly separates out, and (i.e. utilizes Huang
The dissolubility of the effective ingredient such as essence, Radix Puerariae, Fructus Mume, completes the overall process of hydrolysis and alcohol extraction) save Rhizoma Polygonati, Radix Puerariae, Fructus Mume etc.
The natural sex composition of Chinese medicinal components, polyphenols, polygonatum polysaccharide, Radix Puerariae isoflavone, puerarin, organic acid in strengthening wine
And the sugar-lowering components such as biologically active peptide.Meanwhile, add aminoacid in wine, protein, vitamin and calcium, selenium, ferrum, copper,
Trace element necessary to the multiple human body such as phosphorus, potassium.
Detailed description of the invention
Below by embodiment, the invention will be further described, but the practical range of the present invention is not limited to this.
Embodiment one
1, the selection of raw material
(1) Fructus Vitis viniferae: the Fructus Vitis viniferae age of tree is more than 10 years, and plant is healthy, and the big Maturity of fringe is good, and pol in 200g/kg, kind is
Cabernet Sauvignon, weight 5000kg.
(2) Rhizoma Polygonati: SHENGHUANG essence, individual big plumpness, body weight matter is hard and softness person is preferred.Surface brown color, section yellow-white, sugar
Property foot, free from admixture.
(3) Radix Puerariae: Wild Pueraria, with matter hard and weigh, tangent plane is coarse, rich mealiness, and containing a large amount of fibers, seen from transverse section by
The concentric circles that fiber is formed, longitudinal section fibres visible is alternate with bisque, forms longitudinal grin, and that hears is tasteless, and mouth gustation is micro-sweet.
(4) Fructus Mume: natural sun-dried Fructus Mume, individual pork is thick.
2, cleaning is broken
(1) Fructus Vitis viniferae: Fructus Vitis viniferae, before broken, first used clean water one time, then used pure water cleaning showers, dried up by Fructus Vitis viniferae
Or after drying, destemming broken.Seed of Fructus Vitis viniferae can not be injured time broken, but guarantee to scratch Pericarpium Vitis viniferae.
(2) Rhizoma Polygonati: go the removal of impurity, is ground into fine granularity.
(3) Radix Puerariae: go the removal of impurity, is ground into fine granularity.
(4) Fructus Mume: go the removal of impurity, flattens the shape that is cut into small pieces.
3 ferment wine brewings
Fermentation for the first time, i.e. to grape fermentation.Broken Fructus Vitis viniferae is pumped into fermentation tank, adds yeast (yeast immediately
Access amount is this area conventional amount used), make Fructus Vitis viniferae enter the fermentation phase as early as possible, control temperature in the range of 18 28 DEG C,
Ferment 6 days.Wine liquid pol is 10g/L, is separated by skin slag, obtains Fructus Vitis viniferae wine liquid 3150kg, proceeds to second time and ferments.
Second time fermentation: the Fructus Vitis viniferae wine liquid fermented for the first time is added the Rhizoma Polygonati powder 25.2kg crushed, powder of Radix Puerariae
12.6kg, Fructus Mume 6.3kg (adding proportion is that every liter of Fructus Vitis viniferae wine liquid adds 8 grams of Rhizoma Polygonati powder, powder of Radix Puerariae 4 grams, Fructus Mume 2 grams) are carried out immediately
Circulation, makes Rhizoma Polygonati powder, powder of Radix Puerariae, Fructus Mume fully uniformly merge with Fructus Vitis viniferae wine liquid.Once circulated every 8 hours, temperature later
Degree controls in the range of 18 28 DEG C.Circulation 30 minutes every time, Time Continuous is 7 days, and pol is 3.8g/L, stops circulation,
Enter quiet fermentation under room temperature.Through 6 weeks normal temperature fermentation, malic acid transferred lactic acid completely to.
4, storage
The wine liquid fermented is separated, removes Rhizoma Polygonati, Radix Puerariae, Fructus Mume precipitate, inject storage in storage tank, use nitrogen
Sealing gland wine face, tightens upper cover, enters the storage aging phase.Store 24 months.
5, filter
With plate-sheet-type microfroc filter, the Rhizoma Polygonati wine stored is filtered, remove the bulky grain thing in wine liquid further
Money and floating thing, make wine body sparkling and crystal-clear bright.
6, fill
With ultraviolet, bottle stopper is sterilized, use purified water wash bottle, enter automatic filling line, complete fill, gland, labeling, dress
Case.General flavone content 285mg/L, sugar-free extract 23.5mg/L.
Embodiment two
1, the selection of raw material
(1) Fructus Vitis viniferae: the Fructus Vitis viniferae age of tree is more than 10 years, and plant is healthy, and the big Maturity of fringe is good, and pol in 210g/kg, kind is
Cabernet Sauvignon, weight 10000kg.
(2) Rhizoma Polygonati: SHENGHUANG essence, individual big plumpness, body weight matter is hard and softness person is preferred.Surface brown color, section yellow-white, sugar
Property foot, free from admixture.
(3) Radix Puerariae: Wild Pueraria, matter weighs firmly, tangent plane is coarse, rich mealiness, and containing a large amount of fibers, transverse section is visible by fibre
The concentric circles that dimension is formed, longitudinal section fibres visible is alternate with bisque, forms longitudinal grin, and that hears is tasteless, and mouth gustation is micro-sweet.
(4) Fructus Mume: natural sun-dried Fructus Mume, individual pork is thick.
(5) Fructus Crataegi: big with fruit, meat thick, core is little, the red person of skin is preferred.
2, cleaning is broken
(1) Fructus Vitis viniferae: Fructus Vitis viniferae, before broken, first used clean water one time, then used pure water cleaning showers, dried up by Fructus Vitis viniferae
Or after drying, destemming broken.Seed of Fructus Vitis viniferae can not be injured time broken, but guarantee to scratch Pericarpium Vitis viniferae.
(2) Rhizoma Polygonati: go the removal of impurity, is ground into fine granularity.
(3) Radix Puerariae: go the removal of impurity, is ground into fine granularity.
(4) Fructus Mume: go the removal of impurity, flattens the shape that is cut into small pieces.
(5) Fructus Crataegi: go the removal of impurity, flattens the shape that is cut into small pieces.
3, ferment wine brewing
Fermentation for the first time, i.e. to grape fermentation.Broken Fructus Vitis viniferae is pumped into fermentation tank, adds yeast (yeast immediately
Access amount is this area conventional amount used), make Fructus Vitis viniferae enter the fermentation phase as early as possible, control temperature in the range of 18 28 DEG C,
Ferment 7 days.Wine liquid pol is 8.5g/L, is separated by skin slag, obtains Fructus Vitis viniferae wine liquid 6250kg, proceeds to second time and ferments.
Second time fermentation: the Rhizoma Polygonati powder 50kg that the Fructus Vitis viniferae wine liquid fermented for the first time addition is crushed, powder of Radix Puerariae 25kg,
(adding proportion is that every liter of Fructus Vitis viniferae wine liquid adds 8 grams of Rhizoma Polygonati powder, powder of Radix Puerariae 4 grams, Fructus Mume 2 grams, Fructus Crataegi 4 for Fructus Mume 12.5kg, Fructus Crataegi 25kg
Gram) be circulated immediately, make Rhizoma Polygonati powder, powder of Radix Puerariae, dark plum and hawthorn etc. fully uniformly merge with Fructus Vitis viniferae wine liquid.The least every 8
Shi Jinhang once circulates, and temperature controls in the range of 18 28 DEG C.Circulation 30 minutes every time, Time Continuous is 7 days, and pol is
3.7g/L, stops circulation, enters quiet fermentation under room temperature.Through 45 days normal temperature fermentation, malic acid transferred lactic acid completely to.
4, storage (aging)
The wine liquid fermented is separated, removes Rhizoma Polygonati, Radix Puerariae, dark plum and hawthorn precipitate, inject storage in storage tank
Hide, seal wine face with nitrogen, tighten upper cover, enter the storage aging phase.Store 24 months.
5, filter
With plate-sheet-type microfroc filter, the Rhizoma Polygonati wine stored is filtered, remove the bulky grain thing in wine liquid further
Money and floating thing, make wine body brilliant crystal-clear bright.
6, fill
With ultraviolet, bottle stopper is sterilized, use purified water wash bottle, enter automatic filling line, complete fill, gland, labeling, dress
Case.General flavone content 288mg/L, sugar-free extract 24mg/L.
Embodiment three
1, the selection of raw material
(1) Fructus Vitis viniferae: the Fructus Vitis viniferae age of tree is more than 10 years, and plant is healthy, and the big Maturity of fringe is good, and pol in 215g/kg, kind is
Cabernet Sauvignon, weight 15000kg.
(2) Rhizoma Polygonati: SHENGHUANG essence, individual big plumpness, body weight matter is hard and softness person is preferred.Surface brown color, section yellow-white, sugar
Property foot, free from admixture.
(3) Radix Puerariae: Wild Pueraria, matter weighs firmly, tangent plane is coarse, rich mealiness, and containing a large amount of fibers, transverse section is visible by fibre
The concentric circles that dimension is formed, longitudinal section fibres visible is alternate with bisque, forms longitudinal grin, and that hears is tasteless, and mouth gustation is micro-sweet.
(4) Fructus Mume: natural sun-dried Fructus Mume, individual pork is thick.
(5) Rhizoma Dioscoreae: selecting high-quality Rhizoma Dioscoreae, Rhizoma dioscoreae is optimal.
(6) Fructus Lycii: high-quality lycium barbarum.
2, cleaning is broken
(1) Fructus Vitis viniferae: Fructus Vitis viniferae, before broken, first used clean water one time, then used pure water cleaning showers, dried up by Fructus Vitis viniferae
Or after drying, destemming broken.Seed of Fructus Vitis viniferae can not be injured time broken, but guarantee to scratch Pericarpium Vitis viniferae.
(2) Rhizoma Polygonati: go the removal of impurity, is ground into fine granularity.
(3) Radix Puerariae: go the removal of impurity, is ground into fine granularity.
(4) Fructus Mume: go the removal of impurity, flattens the shape that is cut into small pieces.
(5) Rhizoma Dioscoreae: remove impurity, separately size, bubble profit to thoroughly, is cut sheet, is dried.
(6) Fructus Lycii: go the removal of impurity, is ground into fine granularity.
3, ferment wine brewing
Fermentation for the first time, i.e. to grape fermentation.Broken Fructus Vitis viniferae is pumped into fermentation tank, adds yeast (yeast immediately
Access amount is this area conventional amount used), make Fructus Vitis viniferae enter the fermentation phase as early as possible, control temperature in the range of 18 28 DEG C,
Ferment 7 days.Wine liquid pol is 9g/L, is separated by skin slag, obtains Fructus Vitis viniferae wine liquid 9450kg, proceeds to second time and ferments.
Second time fermentation: the Fructus Vitis viniferae wine liquid fermented for the first time is added the Rhizoma Polygonati powder 75.6kg crushed, powder of Radix Puerariae
37.8kg, Fructus Mume 19.8kg, Rhizoma Dioscoreae 19.8kg, Fructus Lycii 19.8kg (adding proportion be every liter of Fructus Vitis viniferae wine liquid add 8 grams of Rhizoma Polygonati powder,
Powder of Radix Puerariae 4 grams, Fructus Mume 2 grams, Rhizoma Dioscoreae 2 grams, Fructus Lycii 2 grams) it is circulated immediately, make Rhizoma Polygonati powder, powder of Radix Puerariae, Fructus Mume, Rhizoma Dioscoreae, Chinese holly
Fructus Lyciis etc. fully uniformly merge with Fructus Vitis viniferae wine liquid.Once circulating every 8 hours, temperature controls the model at 18 28 DEG C later
In enclosing.Circulation 30 minutes every time, Time Continuous is 7 days, and pol is 3.9g/L, stops circulation, enters quiet fermentation under room temperature.Through 49
It normal temperature fermentation, malic acid transfers lactic acid completely to.
4, storage
The wine liquid fermented is separated, removes the precipitate such as Rhizoma Polygonati, Radix Puerariae, Fructus Mume, Rhizoma Dioscoreae, Fructus Lycii, inject storage
Hide storage in tank, seal wine face with nitrogen, tighten upper cover, enter the storage aging phase.Store 24 months.
5, filter
With plate-sheet-type microfroc filter, the Rhizoma Polygonati wine stored is filtered, remove the bulky grain thing in wine liquid further
Money and floating thing, make wine body brilliant crystal-clear bright.
6, fill
With ultraviolet, bottle stopper is sterilized, use purified water wash bottle, enter automatic filling line, complete fill, gland, labeling, dress
Case.General flavone content 280mg/L, sugar-free extract 24.6mg/L.
Embodiment four
1, the selection of raw material
(1) Fructus Vitis viniferae: the Fructus Vitis viniferae age of tree is more than 10 years, and plant is healthy, and the big Maturity of fringe is good, and pol in 221g/kg, kind is
Cabernet Sauvignon, weight 16000kg.
(2) Rhizoma Polygonati: SHENGHUANG essence, individual big plumpness, body weight matter is hard and softness person is preferred.Surface brown color, section yellow-white, sugar
Property foot, free from admixture.
(3) Radix Puerariae: Wild Pueraria, matter weighs firmly, tangent plane is coarse, rich mealiness, and containing a large amount of fibers, transverse section is visible by fibre
The concentric circles that dimension is formed, longitudinal section fibres visible is alternate with bisque, forms longitudinal grin, and that hears is tasteless, and mouth gustation is micro-sweet.
(4) Fructus Mume: natural sun-dried Fructus Mume, individual pork is thick.
(5) Flos Chrysanthemi: natural high-quality Flos Chrysanthemi Indici.
2, cleaning is broken
(1) Fructus Vitis viniferae: Fructus Vitis viniferae, before broken, first used clean water one time, then used pure water cleaning showers, dried up by Fructus Vitis viniferae
Or after drying, destemming broken.Seed of Fructus Vitis viniferae can not be injured time broken, but guarantee to scratch Pericarpium Vitis viniferae.
(2) Rhizoma Polygonati: go the removal of impurity, is ground into fine granularity.
(3) Radix Puerariae: go the removal of impurity, is ground into fine granularity.
(4) Fructus Mume: go the removal of impurity, flattens the shape that is cut into small pieces.
(5) Flos Chrysanthemi: go the removal of impurity, pulverizes.
3, ferment wine brewing
Fermentation, i.e. to grape fermentation, pumps into fermentation tank by broken Fructus Vitis viniferae, adds yeast (yeast immediately for the first time
Access amount is this area conventional amount used), make Fructus Vitis viniferae enter the fermentation phase as early as possible, control temperature in the range of 18 28 DEG C,
Ferment 7 days.Wine liquid pol is 9.5g/L, is separated by skin slag, obtains Fructus Vitis viniferae wine liquid 10240kg, proceeds to second time and ferments.
Second time fermentation: the Rhizoma Polygonati powder 82kg that the Fructus Vitis viniferae wine liquid fermented for the first time addition is crushed, powder of Radix Puerariae 41kg,
(adding proportion is that every liter of Fructus Vitis viniferae wine liquid adds 8 grams of Rhizoma Polygonati powder, powder of Radix Puerariae 4 grams, Fructus Mume 2 grams, chrysanthemum for Fructus Mume 20.5kg, Flos Chrysanthemi 30.75kg
Spend 3 grams) it is circulated immediately, make Rhizoma Polygonati powder, powder of Radix Puerariae, Fructus Mume, Flos Chrysanthemi fully uniformly merge with Fructus Vitis viniferae wine liquid.Later every 8
Hour once circulating, temperature controls in the range of 18 28 DEG C.Circulation 30 minutes every time, Time Continuous is 8 days, pol
For 2.9g/L, stop circulation, enter quiet fermentation under room temperature.Through 49 days normal temperature fermentation, malic acid transferred lactic acid completely to.
4, storage
The wine liquid fermented is separated, removes the precipitate such as Rhizoma Polygonati, Radix Puerariae, Fructus Mume, Flos Chrysanthemi, inject storage in storage tank
Hide, seal wine face with nitrogen, tighten upper cover, enter the storage aging phase.Store 24 months.
5, filter
With plate-sheet-type microfroc filter, the Rhizoma Polygonati wine stored is filtered, remove the bulky grain thing in wine liquid further
Money and floating thing, make wine body brilliant crystal-clear bright.
6, fill
With ultraviolet, bottle stopper is sterilized, use purified water wash bottle, enter automatic filling line, complete fill, gland, labeling, dress
Case.General flavone content 283mg/L, sugar-free extract 25.2mg/L.
Embodiment five
1, the selection of raw material
(1) Fructus Vitis viniferae: the Fructus Vitis viniferae age of tree is more than 10 years, and plant is healthy, and the big Maturity of fringe is good, and pol in 230g/kg, kind is
Cabernet Sauvignon, weight 18000kg.
(2) Rhizoma Polygonati: SHENGHUANG essence, individual big plumpness, body weight matter is hard and softness person is preferred.Surface brown color, section yellow-white, sugar
Property foot, free from admixture.
(3) Radix Puerariae: Wild Pueraria, matter weighs firmly, tangent plane is coarse, rich mealiness, and containing a large amount of fibers, transverse section is visible by fibre
The concentric circles that dimension is formed, longitudinal section fibres visible is alternate with bisque, forms longitudinal grin, and that hears is tasteless, and mouth gustation is micro-sweet.
(4) Fructus Mume: natural sun-dried Fructus Mume, individual pork is thick.
(5) Flos Chrysanthemi: natural high-quality Flos Chrysanthemi Indici.
(6) Fructus Crataegi: big with fruit, meat thick, core is little, the red person of skin is preferred.
(7) Semen Ziziphi Spinosae: oblate or flat ellipse, surface aubergine or puce, smooths glossy or has the excellent of crackle
Matter Semen Ziziphi Spinosae.
2, cleaning is broken
(1) Fructus Vitis viniferae: Fructus Vitis viniferae, before broken, first used clean water one time, then used pure water cleaning showers, dried up by Fructus Vitis viniferae
Or after drying, destemming broken.Seed of Fructus Vitis viniferae can not be injured time broken, but guarantee to scratch Pericarpium Vitis viniferae.
(2) Rhizoma Polygonati: go the removal of impurity, is ground into fine granularity.
(3) Radix Puerariae: go the removal of impurity, is ground into fine granularity.
(4) Fructus Mume: go the removal of impurity, flattens the shape that is cut into small pieces.
(5) Flos Chrysanthemi: go the removal of impurity, pulverizes.
(6) Fructus Crataegi: go the removal of impurity, flattens the shape that is cut into small pieces.
(7) Semen Ziziphi Spinosae: go the removal of impurity, pulverizes.
3, ferment wine brewing
Fermentation for the first time, i.e. to grape fermentation.Broken Fructus Vitis viniferae is pumped into fermentation tank, adds yeast (yeast immediately
Access amount is this area conventional amount used), make Fructus Vitis viniferae enter the fermentation phase as early as possible, control in the range of temperature 18 28 DEG C, fermentation 8
My god.Wine liquid pol is 8.8g/L, is separated by skin slag, obtains Fructus Vitis viniferae wine liquid 10240kg, proceeds to second time and ferments.
Second time fermentation: the Rhizoma Polygonati powder 82kg that the Fructus Vitis viniferae wine liquid fermented for the first time addition is crushed, powder of Radix Puerariae 41kg,
(adding proportion is that every liter of Fructus Vitis viniferae wine liquid adds Rhizoma Polygonati for Fructus Mume 20.5kg, Flos Chrysanthemi 30.75kg, Fructus Crataegi 30.75kg, Semen Ziziphi Spinosae 20.5kg
8 grams of powder, powder of Radix Puerariae 4 grams, Fructus Mume 2 grams, Flos Chrysanthemi 3 grams, Fructus Crataegi 3 grams, Semen Ziziphi Spinosae 2 grams) it is circulated immediately, make Rhizoma Polygonati powder, Radix Puerariae
Powder, Fructus Mume, Flos Chrysanthemi powder, Fructus Crataegi, spiny jujuba seed powder etc. fully uniformly merge with Fructus Vitis viniferae wine liquid.Once followed every 8 hours later
Ring, temperature controls in the range of 18 28 DEG C.Circulation 30 minutes every time, Time Continuous is 8 days, and pol is 2.9g/L, stops
Circulation, enters quiet fermentation under room temperature.Through 49 days normal temperature fermentation, malic acid transferred lactic acid completely to.
4, storage
The wine liquid fermented is separated, removes the precipitate such as Rhizoma Polygonati, Radix Puerariae, Fructus Mume, Flos Chrysanthemi, Fructus Crataegi, Semen Ziziphi Spinosae, note
Enter storage in storage tank, seal wine face with nitrogen, tighten upper cover, enter the storage aging phase.Store 24 months.
5, filter
With plate-sheet-type microfroc filter, the Rhizoma Polygonati wine stored is filtered, remove the bulky grain thing in wine liquid further
Money and floating thing, make wine body brilliant crystal-clear bright.
6, fill
With ultraviolet, bottle stopper is sterilized, use purified water wash bottle, enter automatic filling line, complete fill, gland, labeling, dress
Case.General flavone content 290mg/L, sugar-free extract 26.1mg/L.
Embodiment six
Rhizoma Polygonati grape health care wine embodiment one to five obtained, specification is 750ml/ bottle, 17%vol, delivers to city-level food
Product drug inspections inspection center, tests, and inspection project has: color and luster, clarity, fragrance, taste, style, alcoholic strength, total
Sugar, volatile acid (with Acetometer), total sulfur dioxide are (with SO2Meter), sugar-free extract, flavone, ferrum, copper, lead, potassium sorbate, methanol,
Pathogenic bacterium (Salmonella, staphylococcus aureus, shigella), total plate count, coliform, benzoic acid and sodium benzoate, peace
Match honey, saccharin sodium, cyclamate, amaranth and aluminum color lake, carmine and aluminum color lake thereof.Assay is shown in Table 1.
Table 1 Rhizoma Polygonati of the present invention grape health care wine assay
Below in conjunction with animal function test and try out case to further illustrate its beneficial effect.
Animal function test example
1. material
1.1 subject material: Rhizoma Polygonati grape health care wine of the present invention
1.2 laboratory animal
Kunming mouse, body weight 18-22g, in room temperature (24 ± 2) DEG C, the test chamber of relative humidity (55 ± 10) % is raised,
Freely drink water, fed granules feedstuff.
2. method
The research to diabetic mice hypoglycemic activity of the 2.1 Rhizoma Polygonati grape health care wines of the present invention
Take the kunming mice 60 of body weight 18-22g, often group 20, male and female half and half.It is made into 2% 4 oxygen phonetic with normal saline
Pyridine injection, by the dosage of alloxan solution 200mg/kg, carries out lumbar injection to the mice after fasting 12h.Raise continuously
3d, after fasting 12h, eye socket is taken a blood sample, and separates serum, measures fasting glucose, using blood glucose value more than 13mmol/L as diabetes mould
Type mice.
After modeling successfully, choose diabetic mice 40, often organize 20, female half and half, it is randomly divided into Rhizoma Polygonati Fructus Vitis viniferae
Health promoting wine group and model control group.Separately take the close normal Kunming mouse of quality 20, female half and half, as normal control
Group.Rhizoma Polygonati grape health care wine group gavage 0.3ml every day Rhizoma Polygonati grape health care wine.Model control group and Normal group feed gavage
The normal saline of same volume, once a day, continuous 15d.
Observing the change of mice macroscopic features, and fasting 12h after last gavage every day, eye socket is taken a blood sample, 3500r/min from
Heart 10min, separates and collects serum, measures fasting glucose.
The research to high blood lipid model mice effect for reducing blood fat of the 2.2 Rhizoma Polygonati grape health care wines of the present invention
Taking the kunming mice 60 of body weight 18-22g, often group 20, male and female half and half, be randomly divided into Rhizoma Polygonati grape health care wine
Group, model control group and Normal group.Rhizoma Polygonati grape health care wine group, model control group mice feed high lipid food, the most right
According to group feeding normal feedstuff, feed two weeks continuously.After modeling successfully, Rhizoma Polygonati grape health care wine group gavage 0.3ml every day Rhizoma Polygonati Portugal
Grape health promoting wine.Model control group and Normal group feed the normal saline of gavage same volume, continuous two weeks.After last is administered
Fasting 12h, eye socket blood sampling, 3500r/min is centrifuged 10min, separates and collects serum, measures TG, TC, HDL-C and LDL-C in serum
Content.
3. result
The 3.1 Rhizoma Polygonati grape health care wines of the present invention result of study to diabetic mice hypoglycemic activity
Table 2 Rhizoma Polygonati grape health care wine on the impact of diabetic mice blood glucose (N=20) mmol/L
Note: * * p ＜ 0.01, * p ＜ 0.05 compared with model control group.
As shown in Table 2, the blood sugar concentration pole of model control group is significantly higher than Normal group.Show diabetic mice
Modeling success.Comparing with model control group, Rhizoma Polygonati grape health care wine group blood sugar concentration reduces extremely notable, shows Rhizoma Polygonati grape health
Diabetic mice is reduced blood glucose by wine group certain impact.
The 3.2 Rhizoma Polygonati grape health care wines of the present invention result of study to high blood lipid model mice effect for reducing blood fat
Table 3 Rhizoma Polygonati grape health care wine to TG in high blood lipid model mice serum, the impact of TC, HDL-C, LDL-C (n
=20) mmol/L
Note: compare * * p ＜ 0.01, * p ＜ 0.05 with model control group.
As shown in Table 3, model control group serum TG is significantly higher than Normal group, shows that high blood lipid model is set up.Gavage
After drinking, Rhizoma Polygonati grape health care wine group compares Rhizoma Polygonati grape health with model control group, and TG has pole to significantly reduce, and shows Rhizoma Polygonati Fructus Vitis viniferae
Health promoting wine has pole remarkable effect to reducing serum TG；HDL-C raises extremely notable, shows that Rhizoma Polygonati grape health care wine can effectively raise
HDL-C.Other two changes are less significant compared with model control group.
Show that through results of animal diabetic mice is had necessarily by the Rhizoma Polygonati grape health care wine of gavage 0.3ml/d
Hypoglycemic activity, high blood lipid model mice is had effect for reducing blood fat.
Try out example
1. Zhang, man, 59 years old.There is thirsty, polydipsia, polyuria without bright reason before 4 years in patient, gradually becomes thin and lower limb float
Swollen grade shows, high through examination in hospital blood glucose, is diagnosed as: type Ⅱdiabetes mellitus, gives the antidiabetic drug such as metformin hydrochloride, gliclazide
Thing therapeutic effect is inconspicuous, after while taking hypoglycemic medicine, take the embodiment of the present invention one blood sugar lowering Rhizoma Polygonati Fructus Vitis viniferae protect
Strong wine, every day twice (lunch, dinner), each 100ml, after taking two weeks, to survey blood glucose and be gradually reduced, symptom is clearly better.Clothes
After a course for the treatment of (one month being a course for the treatment of), hypoglycemic medicine dose halves, and thirsty, polydipsia, polyuria etc. show and gradually disappear
Lose, spirit, complexion and and edema of lower limbs be clearly better.After continuing to take two courses for the treatment of, blood glucose is normal, stable, and hypoglycemic medicine stops
Clothes, advise reasonable diet, moderate exercise, follow up a case by regular visits to half a year, have no recurrence.
2. the Meng so-and-so, man, 64 years old.Diabetes mellitus 3 years, at ordinary times self-induction polyorexia, thirsty polydipsia, weak, loose stool etc.
Performance.Survey between fasting glucose 8.2-10.0mmol/l, between post-prandial glycemia 12.6-17.5mmol/l, glucose in urine 2-3+；Take always
Treating with hypoglycemic medicine and subcutaneous insulin injections, weight time light during symptom, glycemic control is undesirable.Through taking the embodiment of the present invention
One blood sugar lowering Rhizoma Polygonati grape health care wine 2 courses for the treatment of (month being a course for the treatment of) for the treatment of, gradually successively decrease insulin dosage, above-mentioned disease
Shape alleviates, and disables insulin after continuing to take 2 courses for the treatment of, and all malaise symptoms disappear, glycemic control 6.2-7.4mmol/l it
Between, glucose in urine (-), continue to strengthen blood glucose after treating 1 course for the treatment of normal, stable, be now in a good state of health.
3. king so-and-so, female, 51 years old.Patient's health before this is always fine, has found hypertension, height the when of health check-up in 2014
Blood fat, high blood viscosity symptom, blood pressure can have 120 180, the diseases such as dizziness, headache, general weakness often occurs.In February, 2015
The part laboratory indexes of 25 days is as follows: triglyceride 1.79, T-CHOL 6.25, HDL1 .33, low-density lipoprotein
White 3.51.Usually have a liking for because of patient drinking, start to drink the grape health care wine of the embodiment of the present invention five in June, 2015,7 days
After, the situation of dizzy headache just alleviates, and the time blood pressure less than month just drops to 90 130, and to examination in hospital, blood fat is also
Drop.The laboratory indexes on July 17th, 2015 is: triglyceride 1.16, T-CHOL 5.28, HDL1 .15, low
Density lipoprotein 3.82.Continuing to take one month, on August 17th, 2015, again chemically examine, the index of above-mentioned item is: triglyceride
0.99, T-CHOL 3.97, HDL1 .23, low density lipoprotein, LDL 2.41.Follow up a case by regular visits to blood pressure so far the most stable, respectively
Item index is the most normal.
4. Chen, female, 49 years old, patient often felt polyorexia, thirsty polydipsia, dizziness, headache, general weakness before 2 years.Warp
Inspection suffers from the diseases such as hypertension, hyperlipidemia, hyperglycemia, and on March 4th, 2015, part laboratory indexes was as follows: glucose 9.69, sweet
Oil three esters 15.57, T-CHOL 14.29, HDL1 .03, low density lipoprotein, LDL 7.86.Having eaten a lot of medicine, blood pressure is anti-
Multiple instability, makes patient the most worried.Therefore start on the basis of drug administration, drink the embodiment of the present invention from March 15th, 2015
The grape health care wine of five, after 1 course for the treatment of, on April 5th, 2015 chemically examines again, and These parameters is: glucose 7.98, triglyceride
8.92, T-CHOL 9.81, HDL1 .36, low density lipoprotein, LDL 4.02.Again chemically examine after persistently drinking half a year: Portugal
Grape sugar 5.94, triglyceride 1.92, T-CHOL 5.90, HDL1 .42, low density lipoprotein, LDL 2.02.
Conclusion: the patient often suffering from diabetes should forbid drinking, because on the one hand, drinking and can increase burden of liver,
And the liver detoxification ability of diabetes patient is poor, drinks and will certainly increase the weight of the burden of liver and cause damage.Meanwhile, it is also easy to send out
Raw hyperlipemia and metabolism disorder.Diabetes are mainly caused by hypoinsulinism.Drink and pancreas can be made to be upset and shadow
Ring the composition of its juice.Wine inherently high heat food, every gram of ethanol can produce 7 kilocalories of heats, diabetes patient's system the most out of control,
Just can cause that sb.'s illness took a turn for the worse.And the most not for suffering from the wine that diabetic population is developed.So, for solving
The requirement that these groups of people " should drink, healthy again ", needs research and development to have the grape health care wine of special health-care effect.The present invention
Use the Chinese crude drug with hypoglycemic activity to prepare with wine co-fermentation, belong to mild health care beverage.Grind through zoopery
Study carefully and show that Rhizoma Polygonati grape health care wine of the present invention has certain blood sugar lowering, the effect of blood fat reducing.And can drink in period of taking medicine.
Some patients is tried out voluntarily, shows that reducing blood sugar and blood fat is respond well.
Claims (8)
1. a blood sugar lowering Rhizoma Polygonati grape health care wine, is characterized in that, Fructus Vitis viniferae is obtained Fructus Vitis viniferae wine liquid, then through fermentation for the first time
Add Chinese medicinal components to carry out preparing after second time is fermented.
2. blood sugar lowering Rhizoma Polygonati grape health care wine as claimed in claim 1, is characterized in that, described Chinese medicinal components includes Rhizoma Polygonati, Pueraria lobota
Root, Fructus Mume.
3. blood sugar lowering Rhizoma Polygonati grape health care wine as claimed in claim 2, is characterized in that, described Chinese medicinal components consumption is, every liter
Fructus Vitis viniferae wine liquid adds Rhizoma Polygonati 8 grams, Radix Puerariae 4 grams, Fructus Mume 2 grams.
4. blood sugar lowering Rhizoma Polygonati grape health care wine as claimed in claim 2 or claim 3, is characterized in that, described Chinese medicinal components also includes trifoliate orange
One in son, Rhizoma Polygonati Odorati, Fructus Hippophae, Fructus Mori, Semen Coicis, Fructus Crataegi, Flos Chrysanthemi, Flos Lonicerae, Semen Ziziphi Spinosae, Fructus Lycii, Rhizoma Dioscoreae, Arillus Longan
Or it is several.
5. blood sugar lowering Rhizoma Polygonati grape health care wine as claimed in claim 1, is characterized in that, described first time ferments: by Fructus Vitis viniferae first
By clean water one time, then use pure water cleaning showers, after drying up or drying, destemming broken；Broken Fructus Vitis viniferae is pumped into and sends out
Ferment tank, adds yeast, makes Fructus Vitis viniferae enter fermentation phase, temperature control 18 28 DEG C as early as possible, ferment 6 10 days；When pol reaches 8-
During 10g/L, carry out skin slag separation, obtain Fructus Vitis viniferae wine liquid.
6. the blood sugar lowering Rhizoma Polygonati grape health care wine as described in claim 1-5 is arbitrary, is characterized in that, described second time is fermented: to
The Fructus Vitis viniferae wine liquid fermented for the first time is proportionally added into Chinese medicinal components, is circulated immediately, make Chinese medicinal components fully and Fructus Vitis viniferae
Wine liquid uniformly merges；Once circulating every 8 hours, temperature controls in the range of 18 28 DEG C later；Circulation every time
30 40 minutes, when pol is less than 4g/L, stop circulation；Quiet fermentation under the room temperature of 68 weeks again, treats that malic acid turns completely
For lactic acid, fermentation ends.
7. the blood sugar lowering Rhizoma Polygonati grape health care wine as described in claim 1-5 is arbitrary, is characterized in that, described Fructus Vitis viniferae, uses the age of tree
More than 10 years, plant is healthy, and the big Maturity of fringe is good, and pol reaches more than 200g/L, overhead the Fructus Vitis viniferae of about 60 centimeters.
8. the production technology of the arbitrary described blood sugar lowering Rhizoma Polygonati grape health care wine of claim 1-5, is characterized in that, step is as follows:
(1) raw material prepares: first by Fructus Vitis viniferae clean water one time, then use pure water cleaning showers, after drying up or drying, destemming
Broken；Chinese medicinal components is gone the removal of impurity, pulverizes standby；
(2) ferment wine brewing
Fermentation for the first time, i.e. grape fermentation: broken Fructus Vitis viniferae is pumped into fermentation tank, add yeast, make Fructus Vitis viniferae enter as early as possible and send out
The ferment phase, in the range of temperature control 18 28 DEG C, ferment 6 10 days, when pol reaches 8-10g/L, carry out skin slag separation, obtain Portugal
Grape wine liquid, proceeds to second time and ferments；
Second time fermentation: the Fructus Vitis viniferae wine liquid fermented for the first time is added the Chinese medicinal components crushed, is circulated immediately, in making
Medicine component fully uniformly merges with Fructus Vitis viniferae wine liquid；Once circulating every 8 hours, temperature controls the model at 18 28 DEG C later
In enclosing；Circulation 30 40 minutes every time, when pol is less than 4g/L, stop circulation；Quiet fermentation under the room temperature of 68 weeks again, treats
Malic acid transfers lactic acid, i.e. fermentation ends completely to；
Then storage aging was no less than 24 months, filtration, fill.
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