CN106237038A - 一种治疗带状疱疹遗留神经痛的洗剂及其制备方法 - Google Patents
一种治疗带状疱疹遗留神经痛的洗剂及其制备方法 Download PDFInfo
- Publication number
- CN106237038A CN106237038A CN201610864960.1A CN201610864960A CN106237038A CN 106237038 A CN106237038 A CN 106237038A CN 201610864960 A CN201610864960 A CN 201610864960A CN 106237038 A CN106237038 A CN 106237038A
- Authority
- CN
- China
- Prior art keywords
- parts
- lotion
- distilled water
- preparation
- herpes zoster
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000006210 lotion Substances 0.000 title claims abstract description 18
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 208000007514 Herpes zoster Diseases 0.000 title claims abstract description 11
- 208000004296 neuralgia Diseases 0.000 title abstract description 8
- 239000003814 drug Substances 0.000 claims abstract description 15
- 239000012153 distilled water Substances 0.000 claims abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000000843 powder Substances 0.000 claims abstract description 9
- 238000003756 stirring Methods 0.000 claims abstract description 4
- 210000000582 semen Anatomy 0.000 claims description 11
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 claims description 11
- 235000001892 vitamin D2 Nutrition 0.000 claims description 11
- 239000011653 vitamin D2 Substances 0.000 claims description 11
- 229940079593 drug Drugs 0.000 claims description 5
- 208000002193 Pain Diseases 0.000 abstract description 12
- 208000024891 symptom Diseases 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 6
- 201000010099 disease Diseases 0.000 abstract description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 4
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 229910021532 Calcite Inorganic materials 0.000 abstract 2
- 240000003146 Lobelia chinensis Species 0.000 abstract 2
- 244000233952 Polygonum bistorta Species 0.000 abstract 2
- 235000014258 Polygonum bistorta Nutrition 0.000 abstract 2
- 240000004922 Vigna radiata Species 0.000 abstract 2
- 235000010721 Vigna radiata var radiata Nutrition 0.000 abstract 2
- 235000011469 Vigna radiata var sublobata Nutrition 0.000 abstract 2
- 229940040145 liniment Drugs 0.000 abstract 1
- 239000000865 liniment Substances 0.000 abstract 1
- 238000010926 purge Methods 0.000 abstract 1
- 238000007873 sieving Methods 0.000 abstract 1
- 231100000614 poison Toxicity 0.000 description 9
- 206010040882 skin lesion Diseases 0.000 description 6
- 231100000444 skin lesion Toxicity 0.000 description 6
- 230000001225 therapeutic effect Effects 0.000 description 5
- 239000003440 toxic substance Substances 0.000 description 5
- 239000002574 poison Substances 0.000 description 4
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 206010048768 Dermatosis Diseases 0.000 description 2
- 229930003451 Vitamin B1 Natural products 0.000 description 2
- 229940035676 analgesics Drugs 0.000 description 2
- 239000000730 antalgic agent Substances 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 208000017520 skin disease Diseases 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 229960003495 thiamine Drugs 0.000 description 2
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 2
- 239000011691 vitamin B1 Substances 0.000 description 2
- 235000010374 vitamin B1 Nutrition 0.000 description 2
- 206010006784 Burning sensation Diseases 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 241000701085 Human alphaherpesvirus 3 Species 0.000 description 1
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 240000005498 Setaria italica Species 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 238000001467 acupuncture Methods 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 210000001217 buttock Anatomy 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 210000001061 forehead Anatomy 0.000 description 1
- 210000001624 hip Anatomy 0.000 description 1
- 229960001680 ibuprofen Drugs 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 229960005321 mecobalamin Drugs 0.000 description 1
- JEWJRMKHSMTXPP-BYFNXCQMSA-M methylcobalamin Chemical compound C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O JEWJRMKHSMTXPP-BYFNXCQMSA-M 0.000 description 1
- 235000007672 methylcobalamin Nutrition 0.000 description 1
- 239000011585 methylcobalamin Substances 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 230000008058 pain sensation Effects 0.000 description 1
- 235000002252 panizo Nutrition 0.000 description 1
- 230000001314 paroxysmal effect Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 238000000554 physical therapy Methods 0.000 description 1
- MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 description 1
- 229960004919 procaine Drugs 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 239000003507 refrigerant Substances 0.000 description 1
- 230000001932 seasonal effect Effects 0.000 description 1
- 230000037384 skin absorption Effects 0.000 description 1
- 231100000274 skin absorption Toxicity 0.000 description 1
- 230000037380 skin damage Effects 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001364 upper extremity Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明涉及一种治疗带状疱疹遗留神经痛的洗剂及其制备方法，药方是：由三棵针100一10份，100一10份，半边莲100一10份，寒水石100一10份，绿豆100一10份，蚤休100一10份，拳参100一10份，蒸馏水3000一200份。制备方法是：将三棵针、半边莲、寒水石、绿豆、蚤休、拳参，磨成细粉，过100目筛，然后将药粉入蒸馏水中搅匀即可，分装塑料瓶中备用。有益效果是：药效通过皮肤吸收，可较快较好发挥清热泻火解毒功效，疗效非常显著，搽药后立即产生一种清凉舒适痛止的感觉。关键是使热清火降，毒邪清解，则肌肤得以安宁，不用单纯止痛药物，神经疼痛症状即随之消失，病能治愈。
Description
技术领域
本发明涉及一种中药洗剂，具体为一种治疗带状疱疹遗留神经痛的洗剂及其制备方法。
背景技术
带状疱疹西医认为属于由带状疱疹病毒引起的皮肤病，开始皮肤损害如粟粒状簇集性疱疹，虽然经过药物治疗病毒杀灭疱疹完全消退后，但最主要突出症状特点是，绝大多数患者遗留神经痛的症状却有增无减。通过临床中观察，疼痛症状轻重不一，一般年青人痛感较轻，遗留神经痛时间较短，中老年人尤其是老年人疼痛最为剧烈，甚时如汤泼火灼，针刺样痛，呈阵发性，难以忍受，重时根本不能睡眠。大多数患者皮损处触之均有灼热感，肤色潮红或暗红，遗留神经痛时间较长，个别可达数月或几年。是一年四季中最常见多发的皮肤病变，患者非常痛苦。
西药治疗一般采用维生素B1、B12注射，内服维生素B1、甲钴胺胶囊、芬必得等营养神经止痛药物。及普鲁卡因封闭，针刺、理疗等。经多例患者反应认为效果不明显，或根本不见效。按中医理论观点辨证，属于火热之邪未得及时清解，蕴聚于皮肤化毒所发。火不清，热不降，毒不解，则肌肤难以安宁。因此，迄今仍乏一种对带状疱疹遗留神经痛，不用注射服药，确有较好疗效直接外用的中药洗剂。
发明内容
发明目的：为解除带状疱疹遗留神经痛给患者造成痛苦，治疗关键是使火热毒邪尽快得以清解，应发明研制出一种治疗此病效果显著的中药洗剂直接外用，为发明此药之目的。
本发明是这样实现的：一种治疗带状疱疹遗留神经痛的洗剂，是由三棵针100一10份，100一10份，半边莲100一10份，寒水石100一10份，绿豆100一10份，蚤休100一10份，拳参100一10份，蒸馏水3000一200份。
本发明所述的洗剂最佳配比范围是：三棵针10份，半边莲10份，寒水石10份，绿豆10份，蚤休10份，拳参10份，蒸馏水200份。
本发明所述的洗剂制备方法是：将三棵针、半边莲、寒水石、绿豆、蚤休、拳参，磨成细粉，过100目筛，然后将药粉入蒸馏水中搅匀即可，分装塑料瓶中备用。
本发明的用药依据是：三棵针，味苦，性寒。现代研究，含有小孽硷，功可清热解毒，临床验之，对红热痛皮肤病变，本品外用疗效较好；半边莲，味苦，性寒。清热解毒功效颇佳。《生草药性备要》：“敷疮消肿毒”；寒水石，味辛、咸，性寒。功可清热泻火。《本经》：“主皮中如火烧”。《别录》：“除时气热盛”；绿豆，味甘，性寒。外敷为清热解毒之良药，《开宝本草》：“治热”；蚤休，味苦，性凉。苦以泄降，寒能清热，具解毒消肿定痛之功；拳参，味苦，性寒。本品外用清热解毒功效较强。《中药志》：“清热解毒，散结消肿”。
本发明的有益效果是：该洗剂搽于病变部位后，药效通过皮肤吸收，可较快较好发挥清热泻火解毒功效。根据临床中患者用后反应，疗效非常显著，搽药后立即产生一种清凉舒适痛止的感觉。由于抓住了病之主因，用药治疗关键是使热清火降，毒邪清解，则肌肤得以安宁，不用单纯止痛药物，神经疼痛症状即随之消失，病能治愈，确实为患者解除了痛苦，均愿接受此法。
洗剂的使用方法：用前摇匀，棉签蘸搽患处，每日6一8次，或不拘次数，有热痛感即搽，直至皮损处红热痛症状全部消失，肤色正常。
临床疗效观察：共治疗137例，男52例，女85例，年龄21一86岁。病程2一17个月。皮损发于身体一侧额部、面部、颈部、季肋部、腰部、腹、臀部、上、下肢等。所有病例均符合带状疱疹遗留神经痛的诊断标准。
疗效评定：痊愈：以皮损处灼热疼痛症状完全消失，肌肤恢复正常之色；好转：皮损处灼热疼痛症状明显消退，肤色基本正常。无效：皮损及灼热疼痛症状基本无改变。
治疗结果：137例中，痊愈112例，好转25例。
具体方式实施
下面用具体实施例来说明本发明的技术特征
实施例一：三棵针20g，半边莲，20g，寒水石20g，绿豆20g，蚤休20g，拳参 20g，蒸馏水600ML。
该洗剂的制备方法是：将三棵针、半边莲、寒水石、绿豆、蚤休、拳参，磨成细粉，过100目筛，然后将药粉入蒸馏水中搅匀，分装塑料瓶中备用。
实施例二：三棵针50g，半边莲50g，寒水石50g，绿豆50g，蚤休50g，拳参50g，蒸馏水1700ML。
该洗剂的制备过程按上述实施例一制备工艺加工即可。
实施例三：三棵针10g，半边莲10g，寒水石10g，绿豆10g，蚤休10g，拳参10g，蒸馏水200ML。
该洗剂的制备过程按上述实施例一制备工艺加工即可。
从实践中对三个实施例方案进行了疗效比较，认为实施例三疗效优于实施例一、实施例二，所以实施例三为最佳实施例，临床治疗效果好。
Claims (3)
1.一种治疗带状疱疹遗留神经痛的洗剂，其特征在于它配方中包含的中药材重量份为：三棵针100一10份，100一10份，半边莲100一10份，寒水石100一10份，绿豆100一10份，蚤休100一10份，拳参100一10份，蒸馏水3000一200份。
2.如权利要求1所述的一种治疗带状疱疹遗留神经痛的洗剂，其特征在于它配方中包含的中药材重量份为：三棵针10份，半边莲10份，寒水石10份，绿豆10份，蚤休10份，拳参10份，蒸馏水200份。
3.一种治疗带状疱疹遗留神经痛的洗剂的制备方法：将三棵针、半边莲、寒水石、绿豆、蚤休、拳参，磨成细粉，过100目筛，然后将药粉入蒸馏水中搅匀即可，分装瓶中备用。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610864960.1A CN106237038A (zh) | 2016-09-30 | 2016-09-30 | 一种治疗带状疱疹遗留神经痛的洗剂及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610864960.1A CN106237038A (zh) | 2016-09-30 | 2016-09-30 | 一种治疗带状疱疹遗留神经痛的洗剂及其制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106237038A true CN106237038A (zh) | 2016-12-21 |
Family
ID=57612013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610864960.1A Pending CN106237038A (zh) | 2016-09-30 | 2016-09-30 | 一种治疗带状疱疹遗留神经痛的洗剂及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106237038A (zh) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1304764A (zh) * | 2000-11-24 | 2001-07-25 | 王玉玺 | 脓胞型植物痤疮晚用霜 |
-
2016
- 2016-09-30 CN CN201610864960.1A patent/CN106237038A/zh active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1304764A (zh) * | 2000-11-24 | 2001-07-25 | 王玉玺 | 脓胞型植物痤疮晚用霜 |
Non-Patent Citations (1)
| Title |
|---|
| 马建国: "《马建国皮肤病外治方药选编》", 31 October 2010, 中医古籍出版社 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102488869B (zh) | 一种用于筋骨疼痛的中药外用搽剂 | |
| CN102793883A (zh) | 一种治疗椎间盘突出、颈椎病、骨质增生的膏药 | |
| CN102008610B (zh) | 一种治疗骨质增生的中药组合物 | |
| CN109966413A (zh) | 一种用于治疗化疗药物所致的周围神经病变的中药外用制剂 | |
| CN102349989B (zh) | 一种治疗颈椎病的中药 | |
| CN102406899B (zh) | 治疗乳腺增生的中药制剂 | |
| CN104027532A (zh) | 一种治疗风湿的中药热敷贴 | |
| CN102335246B (zh) | 治疗骨刺的中药组合物 | |
| CN105031331A (zh) | 一种治疗痛经的肚脐贴剂及其制备方法 | |
| CN103463261A (zh) | 一种治疗腰椎间盘突出的中药制剂 | |
| CN103191271A (zh) | 一种祛痛消炎膏的制备方法 | |
| CN106237038A (zh) | 一种治疗带状疱疹遗留神经痛的洗剂及其制备方法 | |
| CN102949507B (zh) | 一种治疗腰腿痛的中药洗剂及其制备方法 | |
| CN100364603C (zh) | 一种中草药外用组合物 | |
| CN104971286A (zh) | 一种治疗肩腰腿不适症的中药组合物 | |
| CN104173932A (zh) | 一种治疗颈椎病的中药组合物 | |
| CN102772676A (zh) | 治疗实证眩晕的中药 | |
| CN102343081A (zh) | 一种治疗疼痛病纯中药制剂的灸具及治疗疼痛病的纯中药制剂 | |
| CN109620944B (zh) | 一种具有祛风除湿、强筋健骨的中药组合物及其制备方法 | |
| CN114209738A (zh) | 一种清热祛风通络的中药组合物和中药药酒及其制备方法 | |
| CN104784633A (zh) | 一种治疗臀上皮神经炎的外用中药制剂 | |
| CN105194577A (zh) | 一种治疗乳腺增生的药剂 | |
| CN104083465A (zh) | 坐骨神经痛合并腰肌劳损药酒及制法 | |
| CN106511826A (zh) | 一种治疗颈椎病的中药组合物 | |
| CN100408073C (zh) | 治疗腰椎管狭窄症的中成药 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20161221 |