CN106236248A - A kind of radio frequency ablation device, system and method - Google Patents
A kind of radio frequency ablation device, system and method Download PDFInfo
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- CN106236248A CN106236248A CN201610755684.5A CN201610755684A CN106236248A CN 106236248 A CN106236248 A CN 106236248A CN 201610755684 A CN201610755684 A CN 201610755684A CN 106236248 A CN106236248 A CN 106236248A
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- 238000000034 method Methods 0.000 title claims abstract description 53
- 238000007674 radiofrequency ablation Methods 0.000 title claims abstract description 46
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- 239000002003 electrode paste Substances 0.000 claims abstract description 12
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- 238000002679 ablation Methods 0.000 claims description 25
- 238000009432 framing Methods 0.000 claims description 22
- 238000003384 imaging method Methods 0.000 claims description 15
- 230000002093 peripheral effect Effects 0.000 claims description 12
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- 238000006073 displacement reaction Methods 0.000 description 2
- 230000008030 elimination Effects 0.000 description 2
- 238000003379 elimination reaction Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
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- 206010028980 Neoplasm Diseases 0.000 description 1
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- 239000008280 blood Substances 0.000 description 1
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- 238000001816 cooling Methods 0.000 description 1
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- 238000004070 electrodeposition Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
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- 238000009413 insulation Methods 0.000 description 1
- 238000009940 knitting Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000002324 minimally invasive surgery Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
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- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
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- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
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- A61B2018/00636—Sensing and controlling the application of energy
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- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1405—Electrodes having a specific shape
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1405—Electrodes having a specific shape
- A61B2018/1407—Loop
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Abstract
The invention provides a kind of radio frequency ablation device, system and method, this radio frequency ablation device, including: the first conduit and the second conduit, nested first conduit of the second conduit, coaxial with the first conduit；Comprising at least one annular recess on the tube wall of the first conduit, each annular recess fixes a ring electrode；At least two deformation electrode is arranged in the space between the first conduit and the second conduit；Each ring electrode, each deformation electrode connect control portion by electric lead respectively；Control portion controls the first conduit and at least two deformation electrode stretches out the second conduit, and control first conduit enter non-normal tissue, control at least two deformation electrode paste and invest the outer layer of non-normal tissue, control to produce between at least two deformation electrode and at least one ring electrode alternation radio-frequency current, make non-normal tissue's region protein of alternation radio-frequency current process.The scheme that the present invention provides can be effectively improved and melt efficiency.
Description
Technical field
The present invention relates to technical field of medical instruments, particularly to a kind of radio frequency ablation device, system and method.
Background technology
Radio-frequency ablation technique Application comparison in Minimally Invasive Surgery is extensive, and it is often through ablating electrode inserts improper group
In knitting, by high temperature action, removal is melted in non-normal tissue.
At present, in conventional radio frequency ablation device, ablating electrode is frequently located at the fixed position, top of conduit, by leading
Ablating electrode is inserted in non-normal tissue by pipe, and neutral electrode contact human skin tissue, the deactivation temperature of non-normal tissue is low
In normal structure, within the scope of the temperature that normal structure is acceptable, by forming back flow current between ablating electrode and neutral electrode
Heat up heating, it is achieved the elimination to non-normal tissue.In order to realize the elimination to non-normal tissue, owing to one melts electricity
Pole sphere of action is limited, it is often necessary to constantly adjustment ablating electrode position in non-normal tissue, and the mistake of position adjustment
Journey needs to consume the regular hour, and making to melt needs to spend the longer time, cause melt inefficient.
Summary of the invention
Embodiments provide a kind of radio frequency ablation device, system and method, it is possible to be effectively improved and melt efficiency.
A kind of radio frequency ablation device, including: insulated sleeve, at least one ring electrode, at least two deformation electrode and control
Portion processed, wherein,
Described insulated sleeve includes the first conduit of hollow structure and the second conduit of hollow structure, wherein, described second
Nested described first conduit of conduit, coaxial with described first conduit；
Comprising at least one annular recess on the tube wall of described first conduit, each annular recess is used for fixing a ring
Shape electrode, is connected with described control portion；
Described at least two deformation electrode is arranged in the space between described first conduit and described second conduit；
Each ring electrode, each deformation electrode are respectively by the described control portion of respective electric lead connection, wherein,
The electric lead that each ring electrode is corresponding is arranged in described first conduit, and the electric lead that each deformation electrode is corresponding is arranged
In space between described first conduit and described second conduit, mutually insulated between each electric lead；
Described control portion, is used for controlling described first conduit and at least two deformation electrode stretches out described second conduit, and
Control described first conduit and enter non-normal tissue, control described at least two deformation electrode paste and invest described non-normal tissue
Outer layer, controls to produce between described at least two deformation electrode and at least one ring electrode described alternation radio-frequency current, makes described
Non-normal tissue's region protein of alternation radio-frequency current process.
Preferably, above-mentioned radio frequency ablation device, farther include: at least one temperature sensor, wherein,
In at least one temperature sensor described, each temperature sensor is arranged on the ring electrode of correspondence, connects respectively
Receive described control portion, for sensing the temperature of place ring electrode, and give described control portion by described Temperature Feedback；
Described control portion, for the temperature according to described temperature sensor feedback, adjusts described at least two deformation electrode
With the size that at least one ring electrode described produces alternation radio-frequency current.
Preferably, above-mentioned radio frequency ablation device, farther include: localizer, wherein,
Described localizer is arranged on the inwall of described first conduit, is connected with described control portion, is used for obtaining described
The position of one conduit, forms framing signal, and described framing signal is sent to described control portion；
Described control portion, for receiving the described framing signal that described localizer sends, and adjusts according to described framing signal
Whole described first catheter position.
Preferably, above-mentioned radio frequency ablation device, farther include: endoscope, wherein,
Described second conduit outer wall comprises and is parallel to axial groove, and described groove is used for deploying endoscope；
Described endoscope-use, and will in for described first conduit, described at least two deformation electrode and surrounding tissue imaging
Described imaging is transferred to described control portion；
Described control portion, is used for receiving described imaging, according to described imaging, to described first conduit and at least two deformation
Electrode is adjusted.
Preferably, described control portion, including: control dilaton unit and control radio frequency subelement, wherein,
Described control dilaton unit, is used for controlling described first conduit and at least two deformation electrode stretches out described second
Conduit, controls described first conduit and enters non-normal tissue, after non-normal tissue is ubiquitinated, control described first conduit and extremely
Few two deformation electrodes described second conduit of retraction；
Described control radio frequency subelement, is connected with the radio-frequency signal generator of peripheral hardware, occurs for receiving the radio frequency of described peripheral hardware
Device send alternation radio-frequency voltage, and described alternation radio-frequency voltage is sent to described at least two deformation electrode with described at least
One ring electrode, controls to produce between described at least two deformation electrode and at least one ring electrode described alternation radio frequency electrical
Stream.
Preferably, described control radio frequency subelement, it is used for:
Electric lead corresponding for each ring electrode described is connected the first output in the radio-frequency signal generator of described peripheral hardware
End, connects the second outfan in the radio-frequency signal generator of described peripheral hardware, control by electric lead corresponding for each deformation electrode described
In system at least one ring electrode described and described at least two deformation electrode, each deformation electrode receives described first output
End and the radio frequency alternating voltage of described second outfan output.
A kind of radio frequency ablation system, it is characterised in that including: any of the above-described described radio frequency ablation device and radio frequency occur
Device, wherein,
Described radio frequency ablation device is connected with described radio-frequency signal generator, for receiving the alternation that described radio-frequency signal generator sends
Voltage.
A kind of radio-frequency (RF) ablation method realized based on any of the above-described described radio frequency ablation device, including:
Control the first conduit and enter non-normal tissue；
Control at least two deformation electrode paste and invest the outer layer of described non-normal tissue；
Control to produce between described at least two deformation electrode and described first at least one ring electrode supravasal alternation
Radio-frequency current, makes non-normal tissue's region protein of described alternation radio-frequency current process.
Preferably, said method, farther include: the temperature sensor of correspondence is set on each ring electrode；
Produce between described control described at least two deformation electrode and described first at least one ring electrode supravasal
Alternation radio-frequency current, including:
Temperature by described temperature sensor senses place ring electrode；
The temperature arrived according to described temperature sensor senses, adjust described at least two deformation electrode with described at least one
The size of alternation radio-frequency current is produced between ring electrode.
Preferably, said method, farther include: at described first pipe inner wall, localizer is set；
After described control at least two deformation electrode paste invests the outer layer of described non-normal tissue, in described control institute
State before producing alternation radio-frequency current between at least two deformation electrode and described first at least one ring electrode supravasal, enter
One step includes:
Obtained the position of described first conduit by described localizer, form framing signal；
Described first conduit and the position of described at least two deformation electrode is adjusted according to described framing signal.
Embodiments provide a kind of radio frequency ablation device, system and method, this radio frequency ablation device, in insulation
Sleeve pipe includes the first conduit of hollow structure and the second conduit of hollow structure, wherein, nested described first conduit of the second conduit,
Coaxial with described first conduit；Comprising at least one annular recess on the tube wall of the first conduit, each annular recess is for solid
A fixed ring electrode, is connected with control portion；At least two deformation electrode is arranged between the first conduit and described second conduit
In space；Each ring electrode, each deformation electrode connect control portion by respective electric lead respectively, wherein, each
The electric lead that individual ring electrode is corresponding is arranged in the first conduit, and the electric lead that each deformation electrode is corresponding is arranged at first and leads
In space between pipe and the second conduit, mutually insulated between each electric lead；Control portion controls the first conduit and at least two deformation electricity
The second conduit is stretched out in pole, and controls the first conduit and enter non-normal tissue, controls at least two deformation electrode paste and invests improper
The outer layer of tissue, controls to produce between any one ring electrode at least two deformation electrode and at least one ring electrode to hand over
Varying firing rate electric current, makes non-normal tissue's region protein of alternation radio-frequency current process, due to a ring electrode and at least two
Multiple Guan Bi circuit is formed by non-normal tissue between individual deformation electrode, such that it is able to simultaneously from improper group of multiple contact point pairs
Knit and melt, it is possible to be effectively improved and melt efficiency.
Accompanying drawing explanation
In order to be illustrated more clearly that the embodiment of the present invention or technical scheme of the prior art, below will be to embodiment or existing
In having technology to describe, the required accompanying drawing used is briefly described, it should be apparent that, the accompanying drawing in describing below is the present invention
Some embodiments, for those of ordinary skill in the art, on the premise of not paying creative work, it is also possible to according to
These accompanying drawings obtain other accompanying drawing.
Fig. 1 is the cross-sectional view of a kind of radio frequency ablation device that one embodiment of the invention provides；
Fig. 2 is the structural representation of a kind of radio frequency ablation device that another embodiment of the present invention provides；
Fig. 3 is the structural representation of a kind of radio frequency ablation device that another embodiment of the present invention provides；
Fig. 4 is the structural representation of a kind of radio frequency ablation device that another embodiment of the present invention provides；
Fig. 5 is that the first conduit of providing of another embodiment of the present invention, deformation electrode are positioned at the upward view of the second conduit；
Fig. 6 is the structural representation of a kind of radio frequency ablation system that one embodiment of the invention provides；
Fig. 7 is the flow chart of a kind of radio-frequency (RF) ablation method that one embodiment of the invention provides；
Fig. 8 is the structural representation of a kind of radio frequency ablation device that another embodiment of the present invention provides；
Fig. 9 is the flow chart of a kind of radio-frequency (RF) ablation method that another embodiment of the present invention provides.
Detailed description of the invention
For making the purpose of the embodiment of the present invention, technical scheme and advantage clearer, below in conjunction with the embodiment of the present invention
In accompanying drawing, the technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is
The a part of embodiment of the present invention rather than whole embodiments, based on the embodiment in the present invention, those of ordinary skill in the art
The every other embodiment obtained on the premise of not making creative work, broadly falls into the scope of protection of the invention.
As it is shown in figure 1, the embodiment of the present invention provides a kind of radio frequency ablation device, it is characterised in that including: insulated sleeve
101, at least one ring electrode 102, at least two deformation electrode 103 and control portion 104, wherein,
Described insulated sleeve 101 includes the first conduit 1011 of hollow structure and the second conduit 1012 of hollow structure, its
In, nested described first conduit 1011 of described second conduit 1012, coaxial with described first conduit 1011；
Comprising at least one annular recess on the tube wall of described first conduit 1011, each annular recess is used for fixing one
Individual ring electrode 102, is connected with described control portion 104；
Described at least two deformation electrode 103 is arranged at the sky between described first conduit 1011 and described second conduit 1012
In gap；
Each ring electrode 102, each deformation electrode 103 connect described control portion by respective electric lead respectively
104, wherein, the electric lead of each ring electrode 103 correspondence is arranged in described first conduit 1011, each deformation electrode
The electric lead of 102 correspondences is arranged in the space between described first conduit 1011 and described second conduit 1012, between each electric lead
Mutually insulated；
Described control portion 104, is used for controlling described first conduit 1011 and at least two deformation electrode 103 stretches out described
Two conduits 1012, and control described first conduit 1011 and enter non-normal tissue, control described at least two deformation electrode 103 and paste
Invest the outer layer of described non-normal tissue, control described at least two deformation electrode 103 and at least one ring electrode 102 described
Produce alternation radio-frequency current, make non-normal tissue's region protein of described alternation radio-frequency current process.
In the embodiment shown in fig. 1, control the first conduit by control portion and at least two deformation electrode stretches out second
Conduit, and control the first conduit and enter non-normal tissue, control at least two deformation electrode paste and invest the outer layer of non-normal tissue,
Control to produce between any one ring electrode at least two deformation electrode and at least one ring electrode alternation radio-frequency current,
Make non-normal tissue's region protein of alternation radio-frequency current process, due between a ring electrode and at least two deformation electrode
Multiple Guan Bi circuit is formed by non-normal tissue, such that it is able to melt from multiple contact point pair non-normal tissues simultaneously,
Can be effectively improved and melt efficiency.
As in figure 2 it is shown, in an alternative embodiment of the invention, above-mentioned radio frequency ablation device, farther include: at least one temperature
Degree sensor 201, wherein,
In at least one temperature sensor 201 described, each temperature sensor is arranged on the ring electrode 102 of correspondence,
It is connected respectively to described control portion 104, for sensing the temperature of place ring electrode, and gives described control by described Temperature Feedback
Portion 104；
Described control portion 104, for the temperature according to described temperature sensor 201 feedback, adjusts described at least two shape
The size of alternation radio-frequency current is produced between variable electrode 103 and at least one ring electrode 102 described.
The temperature sensor arranged on ring electrode by this embodiment, this temperature sensor can be monitored and be produced on electrode
Raw temperature, and Temperature Feedback according to the temperature of feedback, can be adjusted the electric current by electrode to control portion, doctor, thus protects
The temperature that card electrode produces is in controlled range, owing to non-normal tissue's temperature tolerance is poor, i.e. at ratio under relatively low electrode temperature,
Non-normal tissue can be made ubiquitinated, damage without normal tissue, electrode temperature can be made by this temperature sensor
Degree control in the reasonable scope, it is ensured that non-normal tissue can than relatively rapid proteinised while, protection normal structure peace
Quan Xing.
As it is shown on figure 3, in an alternative embodiment of the invention, above-mentioned radio frequency ablation device farther includes: localizer 301,
Wherein,
Described localizer 301 is arranged on the inwall of described first conduit 1011, is connected with described control portion 104, is used for
Obtain the position of described first conduit 1011, form framing signal, and described framing signal is sent to described control portion 104；
Described control portion 104, for receiving the described framing signal that described localizer 301 sends, and according to described location
Signal adjusts described first conduit 1011 position.
The localizer arranged by above-described embodiment is capable of at least one ring in the first conduit and the first conduit
The location of shape electrode, can position deformation electrode according to location, thus ensure the accuracy of ablation range.
As shown in Figure 4, in an alternative embodiment of the invention, above-mentioned radio frequency ablation device, it is characterised in that wrap further
Include: endoscope 401, wherein,
Described second conduit 1012 outer wall comprises and is parallel to axial groove, and described groove is used for deploying endoscope 401；
Described endoscope 401 is used for as described first conduit 1011, described at least two deformation electrode 103 and surrounding tissue
Imaging, and described imaging is transferred to described control portion 104；
Described control portion 104, is used for receiving described imaging, according to described imaging, to described first conduit 1011 and at least
Two deformation electrodes 103 are adjusted.
By above-mentioned endoscope, can receive the first conduit and at least two according to the imaged shape etc. of non-normal tissue
The interelectrode adjustment of individual deformation, makes adjustment process visual by imaging, thus ensure that the accuracy of adjustment.
In an alternative embodiment of the invention, described control portion, it is characterised in that including: control dilaton unit and control
Radio frequency subelement (not shown), wherein,
Described control dilaton unit, is used for controlling described first conduit 1011 and at least two deformation electrode 103 stretches out
Described second conduit 1012, controls described first conduit 1011 and enters non-normal tissue, after non-normal tissue is ubiquitinated, controls
Described first conduit 1011 and at least two deformation electrode 1012 are retracted described second conduit 1012；Can arrange in this process
First catheter length is more than the second catheter length, makes the first conduit stretch out the second conduit by push-and-pull or rotation the first conduit
Outside, enter in non-normal tissue, it addition, in order to enable the first conduit to enter non-normal tissue smoothly, can be arranged
One end of one conduit is needle-like, and this needle-like end enters non-normal tissue.
Described control radio frequency subelement, is connected with the radio-frequency signal generator of peripheral hardware, occurs for receiving the radio frequency of described peripheral hardware
The alternation radio-frequency voltage that device sends, and described alternation radio-frequency voltage is sent to described at least two deformation electrode 103 with described
At least one ring electrode 102, controls to produce between described at least two deformation electrode 103 and at least one ring electrode 102 described
Raw alternation radio-frequency current.In this process, can arrange according to the size of non-normal tissue there is the ring electrode that electric current passes through
Number, such as: when non-normal tissue is less, only one ring electrode can be set and power, then, at least two deformation electricity
Pole just forms closed-loop path with this ring electrode, still can realize multiconductor and melt, when non-normal tissue is bigger, and can
It is set to 2 ring electrodes power, then, in the middle part of at least two deformation electrode in fractal variable electrode and these 2 ring electrodes
Ring electrode 1 forms closed-loop path, and another part deformation electrode is formed with the ring electrode 2 in these 2 ring electrodes and closes back
Road, is effectively guaranteed the accuracy melted and melts efficiency.What deserves to be explained is, above-mentioned control partial deformation electrode is with ring-type
Electrode 1 forms closed-loop path, and another part deformation electrode and ring electrode 2 form the implementation of closed-loop path can be by control
The length that different deformation electrode processed stretches out the second conduit is different so that different deformation electrode from different ring-type interelectrode relatively
Distance difference, the formation closed-loop path that relative distance is nearer.
In an embodiment of the invention, described control radio frequency subelement, for by right for each ring electrode 102 described
The electric lead answered connects the first outfan in the radio-frequency signal generator of described peripheral hardware, by corresponding for each deformation electrode 103 described
Electric lead connect the second outfan in the radio-frequency signal generator of described peripheral hardware, control at least one ring electrode 102 He described
In described at least two deformation electrode 103, each deformation electrode receives described first outfan and described second outfan output
Radio frequency alternating voltage.Achieved by this process and provide radio frequency alternating voltage, compared with DC voltage, radio frequency into closed-loop path
Alternating voltage it can be avoided that material influence by voltage in normal structure produce the displacement such as blood flow in blood vessel if subjected to
The impact of DC voltage makes the part ion in blood move to a direction, and another part ion moves to other direction,
Normal tissue produces impact, and alternating voltage then avoids the generation of this displacement, protects the safety of normal structure
Property.
In order to the relation represented between the first conduit, deformation electrode and the second conduit become apparent from, as it is shown in figure 5,
Can find out intuitively from figure, the first conduit 1011 is coaxial with the second conduit 1012, and the first conduit 1011 and the second conduit
Having space between 1012, filling deformation electrode 103 on this space, it addition, can also arrange groove on the second conduit, endoscope sets
It is placed in this groove.When carrying out ablation operation, the first conduit 1011 and deformation electrode 103 all can receive the control in control portion,
Stretch out the second conduit 1012.
As shown in Figure 6, the embodiment of the present invention provides a kind of radio frequency ablation system, including: any of the above-described described radio frequency disappears
Melt equipment 601 and radio-frequency signal generator 602, wherein,
Described radio frequency ablation device 601 is connected with described radio-frequency signal generator 602, is used for receiving described radio-frequency signal generator 602
The alternating voltage sent.
As it is shown in fig. 7, the embodiment of the present invention provides a kind of based on penetrating that any of the above-described described radio frequency ablation device realizes
Frequently ablation method, this radio-frequency (RF) ablation method may include steps of:
Step 701: control the first conduit and enter non-normal tissue；
Step 702: control at least two deformation electrode paste and invest the outer layer of described non-normal tissue；
Step 703: control between described at least two deformation electrode and described first at least one ring electrode supravasal
Produce alternation radio-frequency current, make non-normal tissue's region protein of described alternation radio-frequency current process.
In an embodiment of the invention, in order to realize radiofrequency ablation procedures is carried out temperature control, it is to avoid temperature is too high
The injury of normal tissue, it is ensured that above-mentioned radio frequency ablation device uses the safety of process, said method, farther includes:
The temperature sensor of correspondence is set on each ring electrode；The detailed description of the invention of step 703, including: by described temperature
The temperature of sensor sensing place ring electrode；The temperature arrived according to described temperature sensor senses, adjusts described at least two
The size of alternation radio-frequency current is produced between deformation electrode and at least one ring electrode described.Such as: the temperature on ring electrode 1
Sensor a senses that Current Temperatures is 20 DEG C, then by this Temperature Feedback to control portion, control portion is by increasing for ring electrode 1
Voltage thinks that ring electrode 1 heats；The most such as: the temperature sensor a on ring electrode 1 senses that Current Temperatures is 50 DEG C, super
Crossed the ability to bear of normal structure, then by this Temperature Feedback to control portion, control portion by for ring electrode 1 reduce voltage with
For ring electrode 1 cooling etc..
In an embodiment of the invention, in order to ensure the accuracy of radio-frequency (RF) ablation position, said method farther includes:
At described first pipe inner wall, localizer is set；After step 702, before step 703, farther include: by described
Localizer obtains the position of described first conduit, forms framing signal；According to described framing signal adjust described first conduit and
The position of described at least two deformation electrode.Such as: non-normal tissue is positioned at position 1, and current first conduit is positioned at position 2,
Then positioner feedback goes out this position 2, and doctor can adjust the first conduit according to this position 2, makes the first conduit be in position 1, then,
According to the position of the first conduit, the position of deformation electrode can be adjusted accordingly, thus ensure the accuracy melted.
As a example by the radio frequency ablation device shown in Fig. 8, launching explanation radio-frequency (RF) ablation method, the method can include walking as follows
Rapid:
Step 900: the temperature sensor of correspondence is set on each ring electrode；
As shown in Figure 8, after the first conduit 8011 and at least two deformation electrode 802 stretch out the second conduit 8012, often
It is provided with the temperature sensor 805 of correspondence on one ring electrode, radio-frequency (RF) ablation can be fed back in time by this temperature sensor
Temperature, with the temperature for feedback, adjust in time output voltage or the output electric current etc. of radio-frequency (RF) ablation.
Step 901: localizer is set at the first pipe inner wall；
As shown in Figure 8, the localizer 807 that the first conduit 8011 inwall is arranged, owing to the first conduit is to insert improper group
Knit such as inside tumor, then by localizer is arranged on the first conduit, it is possible to contribute to positioning accurately, by location
The device location to the first conduit, feeds back framing signal, and position can be adjusted, separately by doctor according to the framing signal of feedback
Outward, orient the position of each ring electrode in the first conduit by this localizer, contribute to doctor's control portion 804, will
Deformation electrode 803 is arranged near ring electrode 802.Such as: when there being 3 ring electrodes on the first conduit, due to improper portion
Bit comparison is little, and only one of which ring electrode enters into improper position, then of only position improper to this entrance, control portion
Ring electrode is powered, then, need to be arranged at deformation electrode the neighbouring ability of the ring electrode at the improper position of this entrance
Closed-loop path can be formed, it is achieved radio-frequency (RF) ablation.What deserves to be explained is, in order to realize positioning for ring electrode exactly, Ke Yi
Ring electrode is arranged around this localizer 807.
Step 902: control the first conduit and at least two deformation electrode stretches out the second conduit；
As shown in Figure 8, after the first conduit 8011 and at least two deformation electrode 803 stretch out the second conduit 8012, at least two
Individual deformation electrode 803 is distributed in umbrella, in this process, can control different deformation electrodes 803 by control portion 804 and stretch out
Different length, thus be distributed to by different deformation electrodes 803 near different ring electrodes 802, contributes to being formed multiple
Closed-loop path, such as: when two ring electrodes of needs (ring electrode 1 and ring electrode 2) carry out radio-frequency (RF) ablation, can be by 5
Individual deformation electrode is scattered in around ring electrode 1, is scattered in around ring electrode 2 by other 5 deformation electrodes, thus builds respectively
Vertical for ring electrode 1 and the current loop of ring electrode 2, it is achieved that multiple spot radio-frequency (RF) ablation.
Step 903: the first conduit enters non-normal tissue；
As shown in Figure 8, the top of the first conduit 8011 is needle-like, and this acicular texture can make the first conduit 8011 can be suitable
Profit enters in non-normal tissue, along with the entrance of the first conduit, the ring electrode 802 being positioned on the first conduit 8011 also into
Inside non-normal tissue.
In this process, doctor can be imaged as by the endoscope 806 being arranged in the groove on the second conduit 8012 wall
The raw position representing non-normal tissue, and carry out catheter position by the localizer 807 being arranged on the first conduit 8011 inwall
Location, to insert the precise location of non-normal tissue.
Step 904: control at least two deformation electrode paste and invest the outer layer of described non-normal tissue；
By at least two deformation electrode 803 is attached to non-normal tissue so that ring electrode 802, non-normal tissue
A part and deformation electrode 803 form closed-loop path, by for ring electrode 802 and deformation electrode 803 input voltage, make ring
Shape electrode 802 and deformation electrode 803 heat up, so that the non-normal tissue's albumen around ring electrode 802 and deformation electrode 803
Change.
Step 905: obtained the position of the first conduit by localizer, forms framing signal；
Step 906: adjust the first conduit and the position of at least two deformation electrode according to framing signal；
Step 905 and the detailed description of the invention of step 906: known the position of the first conduit by this localizer 807 are permissible
Know whether this first conduit is positioned at non-normal tissue position, or whether this first conduit is positioned at the suitable of non-normal tissue
Position, can carry out as much as possible melting by adjusting the position of the first conduit, reduce and melt number of times non-normal tissue.Extremely
The position of few two deformation electrodes 803 is the most relevant, such as to the position of the first catheter position and the first conduit upper annular electrode:
The ring electrode of energising is positioned at the location A of non-normal tissue, then being arranged by partial deformation electrode 803 can be with reach A
Nearest non-normal tissue's outer layer, thus contribute to setting up electricity loop.
Step 907: control between described at least two deformation electrode and described first at least one ring electrode supravasal
Produce alternation radio-frequency current；
In this step, can be optionally deformation electrode and ring electrode input radio frequency electric current, such as: when with ring-type electricity
When pole A and corresponding with A 3 current loops that deformation electrode constructs are as radio-frequency (RF) ablation loop, can be only to this ring-type electricity
Pole A and corresponding with A 3 deformation electrodes apply voltage and form radio-frequency current.The most such as: with ring electrode A and corresponding with A 3
Current loop, ring electrode B and corresponding with B 3 current loops that deformation electrode constructs that individual deformation electrode constructs are made
During for radio-frequency (RF) ablation loop, respectively this ring electrode A and corresponding with A 3 deformation electrodes can be applied voltage, ring electrode
B and corresponding with B 3 deformation electrodes apply voltage and form radio-frequency current.
Step 908: by the temperature of described temperature sensor senses place ring electrode；
With determine temperature whether in radio-frequency (RF) ablation temperature range, such as: when temperature is increased to 50 DEG C may be to normal group
Being woven into injury, relatively low temperature then can not realize melting, and this step then provides radio frequency by temperature sensor for doctor
The Current Temperatures melted.
Step 909: the temperature arrived according to described temperature sensor senses, adjusts described at least two deformation electrode with described
The size of alternation radio-frequency current is produced between at least one ring electrode；
When Current Temperatures is relatively low, doctor can realize increasing temperature by increasing loop current, when Current Temperatures is too high, and doctor
Life can realize reducing temperature, so that temperature controls in more rational scope by reducing loop current.
Step 910: make non-normal tissue's region protein of described alternation radio-frequency current process.
The process of this proteinised process i.e. non-normal tissue inactivation, this proteinised non-normal tissue can be by surrounding
Normal structure is absorbed.What deserves to be explained is, although whole process is capable of multiple spot and melts, disposable by anon-normal as far as possible
Often ablation of tissue falls, but repeatedly disappears for its mode that can still be by the embodiment of the present invention of bigger non-normal tissue
Melt, radio-frequency current can be controlled for smaller non-normal tissue and flow through number and the number of deformation electrode of ring electrode,
As controlled radio-frequency current only by a ring electrode and a deformation electrode, single point ablation can be carried out, illustrate that the present invention is real
Radio frequency ablation device and the radio-frequency (RF) ablation method of executing example offer have motility, and it can carry out changeable control by control portion.
According to such scheme, various embodiments of the present invention, at least have the advantages that
1. the insulated sleeve in radio frequency ablation device includes the first conduit of hollow structure and the second conduit of hollow structure,
Wherein, nested described first conduit of the second conduit, coaxial with described first conduit；At least one is comprised on the tube wall of the first conduit
Annular recess, each annular recess is used for fixing a ring electrode, is connected with control portion；At least two deformation electrode is arranged
In space between the first conduit and described second conduit；Each ring electrode, each deformation electrode are respectively by each
Electric lead connect control portion, wherein, the electric lead that each ring electrode is corresponding is arranged in the first conduit, each deformation
The electric lead that electrode is corresponding is arranged in the space between the first conduit and the second conduit, mutually insulated between each electric lead；Control portion
Control the first conduit and at least two deformation electrode stretches out the second conduit, and control the first conduit and enter non-normal tissue, control
At least two deformation electrode paste invests the outer layer of non-normal tissue, controls at least two deformation electrode and at least one ring electrode
In any one ring electrode between produce alternation radio-frequency current, make non-normal tissue's region protein of alternation radio-frequency current process
Change, owing to forming multiple Guan Bi circuit by non-normal tissue between a ring electrode and at least two deformation electrode, thus can
To melt from multiple contact point pair non-normal tissues simultaneously, it is possible to be effectively improved and melt efficiency.
2. by arranging temperature sensor on ring electrode, so that control portion can be according to the letter of temperature sensor feedback
Number it is adjusted to the output voltage of ring electrode, to realize adjusting the temperature i.e. temperature of radio-frequency (RF) ablation of ring electrode, makes temperature protect
Hold and non-normal tissue can be made ubiquitinated, and don't affect the scope of normal structure, it is achieved that temperature-controllable, can protect simultaneously
The safety of card normal structure.
3. by arranging localizer, it is possible to according to the framing signal of localizer, the first conduit is arranged in non-normal tissue
Relatively rational position, meanwhile, facilitates deformation electrode to find the ring electrode in the first conduit accurately by localizer, is formed and close back
Road, it is ensured that the accuracy of radio-frequency (RF) ablation, can be effectively improved the efficiency of radio-frequency (RF) ablation simultaneously.
4. by arranging endoscope so that doctor directly can know non-normal tissue position by endoscopic imaging accurately
Put and relativeness between the first conduit and deformation electrode and non-normal tissue, and make first to lead according to the imaging of this endoscope
Pipe and deformation electrode move to non-normal tissue, further ensure the accuracy of radio-frequency (RF) ablation process.
5. control described first conduit by control dilaton unit and at least two deformation electrode stretches out described second and leads
Pipe, controls described first conduit and enters non-normal tissue, after non-normal tissue is ubiquitinated, control described first conduit and at least
Two deformation electrodes described second conduits of retraction；It is i.e. the first conduit and the protection of at least two deformation electrode with the second conduit
Set, in use, controls the first conduit and at least two deformation electrode stretches out the second conduit, when stopping using, controls first
Conduit and at least two deformation electrode are retracted the second conduit, make radio frequency ablation device have certain motility, owing to not making
Used time, the first conduit and at least two deformation electrode are retracted the second conduit, conveniently store and carry, simultaneously by by energising
Electric lead is arranged in conduit, it is ensured that the safety of electric lead.
It should be noted that in this article, the relational terms of such as first and second etc is used merely to an entity
Or operation separates with another entity or operating space, and not necessarily require or imply existence between these entities or operation
The relation of any this reality or order.And, term " includes ", " comprising " or its any other variant are intended to non-
Comprising of exclusiveness, so that include that the process of a series of key element, method, article or equipment not only include those key elements,
But also include other key elements being not expressly set out, or also include being consolidated by this process, method, article or equipment
Some key elements.In the case of there is no more restriction, statement the key element " including " and limiting, do not arrange
Except there is also other same factor in including the process of described key element, method, article or equipment.
One of ordinary skill in the art will appreciate that: all or part of step realizing said method embodiment can be passed through
The hardware that programmed instruction is relevant completes, and aforesaid program can be stored in the storage medium of embodied on computer readable, this program
Upon execution, perform to include the step of said method embodiment；And aforesaid storage medium includes: ROM, RAM, magnetic disc or light
In the various medium that can store program code such as dish.
Last it should be understood that the foregoing is only presently preferred embodiments of the present invention, it is merely to illustrate the skill of the present invention
Art scheme, is not intended to limit protection scope of the present invention.All made within the spirit and principles in the present invention any amendment,
Equivalent, improvement etc., be all contained in protection scope of the present invention.
Claims (10)
1. a radio frequency ablation device, it is characterised in that including: insulated sleeve, at least one ring electrode, at least two deformation
Electrode and control portion, wherein,
Described insulated sleeve includes the first conduit of hollow structure and the second conduit of hollow structure, wherein, described second conduit
Nested described first conduit, coaxial with described first conduit；
Comprising at least one annular recess on the tube wall of described first conduit, each annular recess is used for fixing a ring-type electricity
Pole, is connected with described control portion；
Described at least two deformation electrode is arranged in the space between described first conduit and described second conduit；
Each ring electrode, each deformation electrode connect described control portion by respective electric lead respectively, wherein, each
The electric lead that individual ring electrode is corresponding is arranged in described first conduit, and the electric lead that each deformation electrode is corresponding is arranged at institute
State in the space between the first conduit and described second conduit, mutually insulated between each electric lead；
Described control portion, is used for controlling described first conduit and at least two deformation electrode stretches out described second conduit, and control
Described first conduit enters non-normal tissue, controls described at least two deformation electrode paste and invests outside described non-normal tissue
Layer, controls to produce between described at least two deformation electrode and at least one ring electrode described alternation radio-frequency current, makes described friendship
Non-normal tissue's region protein of varying firing rate electric current process.
Radio frequency ablation device the most according to claim 1, it is characterised in that farther include: at least one temperature sensing
Device, wherein,
In at least one temperature sensor described, each temperature sensor is arranged on the ring electrode of correspondence, is connected respectively to
Described control portion, for sensing the temperature of place ring electrode, and gives described control portion by described Temperature Feedback；
Described control portion, for the temperature according to described temperature sensor feedback, adjusts described at least two deformation electrode and institute
State at least one ring electrode and produce the size of alternation radio-frequency current.
Radio frequency ablation device the most according to claim 1, it is characterised in that farther include: localizer, wherein,
Described localizer is arranged on the inwall of described first conduit, is connected with described control portion, is used for obtaining described first and leads
The position of pipe, forms framing signal, and described framing signal is sent to described control portion；
Described control portion, for receiving the described framing signal that described localizer sends, and adjusts institute according to described framing signal
State the first catheter position.
Radio frequency ablation device the most according to claim 1, it is characterised in that farther include: endoscope, wherein,
Described second conduit outer wall comprises and is parallel to axial groove, and described groove is used for deploying endoscope；
Described endoscope-use is in for described first conduit, described at least two deformation electrode and surrounding tissue imaging, and by described
Imaging is transferred to described control portion；
Described control portion, is used for receiving described imaging, according to described imaging, to described first conduit and at least two deformation electrode
It is adjusted.
Described control portion the most according to claim 1, it is characterised in that including: control dilaton unit and control radio frequency
Subelement, wherein,
Described control dilaton unit, is used for controlling described first conduit and at least two deformation electrode stretches out described second and leads
Pipe, controls described first conduit and enters non-normal tissue, after non-normal tissue is ubiquitinated, control described first conduit and at least
Two deformation electrodes described second conduits of retraction；
Described control radio frequency subelement, is connected with the radio-frequency signal generator of peripheral hardware, sends out for receiving the radio-frequency signal generator of described peripheral hardware
The alternation radio-frequency voltage sent, and described alternation radio-frequency voltage is sent to described at least two deformation electrode with described at least one
Ring electrode, controls to produce between described at least two deformation electrode and at least one ring electrode described alternation radio-frequency current.
Radio frequency ablation device the most according to claim 1, it is characterised in that described control radio frequency subelement, is used for:
Electric lead corresponding for each ring electrode described is connected the first outfan in the radio-frequency signal generator of described peripheral hardware, will
The electric lead that each deformation electrode described is corresponding connects the second outfan in the radio-frequency signal generator of described peripheral hardware, controls described
In at least one ring electrode and described at least two deformation electrode, each deformation electrode receives described first outfan and institute
State the radio frequency alternating voltage of the second outfan output.
7. a radio frequency ablation system, it is characterised in that including: the arbitrary described radio frequency ablation device of claim 1 to 6 and penetrating
Frequency generator, wherein,
Described radio frequency ablation device is connected with described radio-frequency signal generator, for receiving the alternation electricity that described radio-frequency signal generator sends
Pressure.
8. the radio-frequency (RF) ablation method realized based on the arbitrary described radio frequency ablation device of claim 1 to 6, its feature exists
In, including:
Control the first conduit and enter non-normal tissue；
Control at least two deformation electrode paste and invest the outer layer of described non-normal tissue；
Control to produce between described at least two deformation electrode and described first at least one ring electrode supravasal alternation radio frequency
Electric current, makes non-normal tissue's region protein of described alternation radio-frequency current process.
Method the most according to claim 8, it is characterised in that farther include: it is right to arrange on each ring electrode
The temperature sensor answered；
Alternation is produced between described control described at least two deformation electrode and described first at least one ring electrode supravasal
Radio-frequency current, including:
Temperature by described temperature sensor senses place ring electrode；
The temperature arrived according to described temperature sensor senses, adjusts described at least two deformation electrode and described at least one is ring-type
The size of alternation radio-frequency current is produced between electrode.
Method the most according to claim 8 or claim 9, it is characterised in that farther include: set at described first pipe inner wall
Put localizer；
After described control at least two deformation electrode paste invests the outer layer of described non-normal tissue, described in described control extremely
Before producing alternation radio-frequency current between two deformation electrodes and described first at least one ring electrode supravasal less, further
Including:
Obtained the position of described first conduit by described localizer, form framing signal；
Described first conduit and the position of described at least two deformation electrode is adjusted according to described framing signal.
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| WO2019015003A1 (en) * | 2017-07-20 | 2019-01-24 | 常州朗合医疗器械有限公司 | Radiofrequency ablation catheter and system |
| CN110772315A (en) * | 2018-07-31 | 2020-02-11 | 贺利氏德国有限两合公司 | Catheter with segmented electrodes and method of making same |
| CN114376718A (en) * | 2022-02-21 | 2022-04-22 | 安徽省立医院(中国科学技术大学附属第一医院) | Arrhythmia radio frequency ablation protection device |
| CN118252600A (en) * | 2024-04-17 | 2024-06-28 | 北京先瑞达医疗科技有限公司 | Radiofrequency ablation device and control method |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2019015003A1 (en) * | 2017-07-20 | 2019-01-24 | 常州朗合医疗器械有限公司 | Radiofrequency ablation catheter and system |
| CN110772315A (en) * | 2018-07-31 | 2020-02-11 | 贺利氏德国有限两合公司 | Catheter with segmented electrodes and method of making same |
| CN114376718A (en) * | 2022-02-21 | 2022-04-22 | 安徽省立医院(中国科学技术大学附属第一医院) | Arrhythmia radio frequency ablation protection device |
| CN114376718B (en) * | 2022-02-21 | 2022-07-22 | 安徽省立医院(中国科学技术大学附属第一医院) | Arrhythmia radio frequency ablation protection device |
| CN118252600A (en) * | 2024-04-17 | 2024-06-28 | 北京先瑞达医疗科技有限公司 | Radiofrequency ablation device and control method |
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