CN106236108A - Intelligence Wicresoft blood glucose continuous monitor system - Google Patents
Intelligence Wicresoft blood glucose continuous monitor system Download PDFInfo
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- CN106236108A CN106236108A CN201610763894.9A CN201610763894A CN106236108A CN 106236108 A CN106236108 A CN 106236108A CN 201610763894 A CN201610763894 A CN 201610763894A CN 106236108 A CN106236108 A CN 106236108A
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- blood glucose
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- 239000008103 glucose Substances 0.000 title claims abstract description 69
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
- A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6802—Sensor mounted on worn items
- A61B5/681—Wristwatch-type devices
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/685—Microneedles
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- A—HUMAN NECESSITIES
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- A61B5/74—Details of notification to user or communication with user or patient ; user input means
- A61B5/746—Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms
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Abstract
The present invention proposes a kind of intelligence Wicresoft blood glucose continuous monitor system, including: sensor probe, monitoring terminal；Described sensor probe connects described monitoring terminal；Described sensor probe is for monitoring the blood sugar concentration of human body；Described monitoring terminal measures blood sugar for human body value in real time, and blood glucose value is wirelessly transmitted to mobile terminal or computer terminal；Described monitoring terminal includes core system, frontend amplifying circuit, power circuit, battery backup system, button and LED display circuit, usb circuit.The present invention can complete the quickly continuous print detection to human blood glucose concentration, and it is little to have wound, and pain is little, and beneficially patient carries out self-monitoring.
Description
Technical field
The present invention relates to sensor technical field, particularly to a kind of intelligence Wicresoft blood glucose continuous monitor system.
Background technology
Diabetes are one of four big diseases of harm human health, and its Symptoms is glucose content in blood and urine
Abnormal.The diabetics that China makes a definite diagnosis at present is about 1.1 hundred million, but deposits according to conservative estimation, prediabetes i.e. blood glucose
Crowd at impaired glucose tolerance is about 1.4 hundred million people, but, this crowd owing to not carrying out actively examination, it is therefore more likely that
Diabetics is progressively developed in the case of not controlling.Lineal relative has diabetics, age more than 45 years old,
The BMI fat personage more than 23, blood pressure blood fat index exceeds standard in health check-up, to suffer from heart, cardiovascular and cerebrovascular disease, gestational diabetes pregnant
The crowds such as woman, polycystic ovary patient, long-term lacking motion, Long-term Hormone and Obese children, broadly fall into the height of diabetes
Danger crowd, it should accept blood glucose inspection in time and on time.
Research finds, whether the first patients with type Ⅰ DM or Second-Type diabetes, be advantageously controlled permissible to blood glucose
Reduce the generation of diabetic complication.So, the permanently effective monitoring to blood glucose has weight for control and treatment diabetes
The meaning wanted.
The blood glucose value of diabetics is affected by diet, motion etc. had larger fluctuation in one day, generally required many
Secondary detect it adjusts dosage and therapeutic strategy with timely.The currently mainly method by adopting finger blood carries out external blood glucose
Detection, every day, repeated detection can bring severe pain and inconvenience to patient undoubtedly.In recent years, for the blood glucose of real-time continuous monitoring
Sensor has become as the focus of research and development, and wherein, needle-like glucose sensor is due to its simple in construction, the implantable advantage such as by force
And paid close attention to widely.How interference with electroactive material complicated and changeable due to internal milieu, strengthen the anti-dry of sensor
Disturb ability, raising sensitivity and response time and become, with the range of linearity etc., the emphasis that implanted detection is researched and developed.
Thrusting wound and patient pain to improve sensitivity, reduction response time reduction, this patent have developed one
By the blood glucose monitoring system based on single needle glucose sensor.Single needle structure is possible not only to reduce the thorn people to human body further
Wound and sensation of pricking, and improve sensitivity because being greatly reduced electrode spacing, reduce response time.Three-electrode system can
Constitute differential configuration, it is possible to effectively get rid of the interference of some internal electric active matter confrontation sensors, be conducive to improving anti-interference
Property.
Summary of the invention
The purpose of the present invention is intended at least solve one of described technological deficiency.
To this end, it is an object of the invention to propose a kind of intelligence Wicresoft blood glucose continuous monitor system, can complete human body blood
The quickly continuous print detection of sugar concentration, and it is little to have wound, and pain is little, and beneficially patient carries out self-monitoring.
To achieve these goals, the present invention provides a kind of intelligence Wicresoft blood glucose continuous monitor system, including: sensor is visited
Pin, monitoring terminal；Described sensor probe connects described monitoring terminal；
Described sensor probe is for monitoring the blood sugar concentration of human body；
Described monitoring terminal measures blood sugar for human body value in real time, and blood glucose value is wirelessly transmitted to mobile terminal or computer
Terminal；
Described monitoring terminal includes core system, frontend amplifying circuit, power circuit, battery backup system, button and LED
Display circuit, usb circuit；
The input of described frontend amplifying circuit connects described sensor probe, the output termination of described frontend amplifying circuit
Described core system, described power circuit connects the power end of described core system, and described battery backup system meets described kernel system
The power end of system, the outfan of described core system is connected with button and LED display circuit, usb circuit respectively, described interior
Core system wireless connects mobile terminal or computer terminal.
Further, also including that shell, described enclosure are provided with monitoring terminal, described sensor probe is inserted in shell
On.
Further, described case surface is additionally provided with system run indicator and bluetooth connects display lamp, and described system is transported
Row display lamp and described bluetooth connect display lamp and connect described button and LED display circuit respectively.
Further, USB interface is also installed in the side of described shell.
Further, described core system selects the microprocessor nRf51822 integrating bluetooth communication.
Further, described frontend amplifying circuit uses the amplifier of MAX4225 model.
Further, the grinding section part coating a thin layer electrically insulating silicone rubber of described sensor probe, needle point will be arranged on
Semicircle groove on working electrode fix with auxiliary electrode, working electrode and auxiliary electrode are covered in Ag/AgC1 reference respectively
Electrode both sides.
Further, described power circuit select TPS62260 model chip as system DC-DC switching power supply,
Selecting BQ24040 is lithium cell charging chip.
Further, described battery backup system selects S-8211CCU as battery discharge protection chip.
Further, described usb circuit includes USB type C interface protection circuit and USB type C interface electricity
Road, described USB type C interface protection circuit connects USB type C interface circuit.
The intelligent Wicresoft blood glucose monitoring system of the present invention is a kind of based on mobile Internet, towards the novel blood glucose of family
Monitoring instrument, it can provide the user continual, long-time blood sugar monitoring, and user wears in arm so that User Activity is empty
Between bigger, improve the convenience of blood glucose monitoring.Acupuncture type blood sampling formula blood glucose meter can be replaced completely, due to mobile network in recent years
Network and the fast development of microelectric technique, the condition of embedded technology application reaches its maturity so that blood sugar monitoring has had more preferable solution
Certainly scheme.Embedded technology have the prominent advantages that low cost, volume are little, application is flexible.
The intelligent Wicresoft blood glucose monitoring system of the present invention can complete the quickly continuous print detection to human blood glucose concentration, and
And it is little to have wound, pain is little, and beneficially patient carries out self-monitoring.This intelligence Wicresoft blood glucose monitoring system uses SOC Mode
NRF51822 blue tooth integrated single-chip microcomputer, be equipped with blood sugar test circuit, power supply and battery circuit, there is simple to operate, power consumption
The advantages such as low, measurement is rapid, and up to 1000 historical datas can be stored, it is simple to patient grasps the change of oneself blood sugar concentration and becomes
Gesture, uses rational application method.
Invention applies wireless Internet transmission technology and Embedded System Design, can give and need the trouble of blood sugar monitoring
Person obtains patient's dynamic glucose signal in the case of normal activity with bigger freedom of movement.Use embedded technology with relatively low
Cost by wireless Internet technologies transmit blood glucose level data to mobile terminal, long-range blood glucose can be achieved by mobile phone A PP
Monitoring, no longer has the requirement of harshness to the position at patient place, effectively overcomes what existing common blood glucose monitoring system cannot network to lack
Point.
Aspect and advantage that the present invention adds will part be given in the following description, and part will become from the following description
Obtain substantially, or recognized by the practice of the present invention.
Accompanying drawing explanation
Above-mentioned and/or the additional aspect of the present invention and advantage are from combining the accompanying drawings below description to embodiment and will become
Substantially with easy to understand, wherein:
Fig. 1 is the structure chart of the present invention；
Fig. 2 is the side view of the present invention；
Fig. 3 is the structured flowchart of the monitoring terminal of the present invention；
Fig. 4 is the circuit theory diagrams of the core system of the present invention；
Fig. 5 is the circuit theory diagrams of the frontend amplifying circuit of the present invention；
Fig. 6 is the circuit theory diagrams of the USB type C interface circuit of the present invention；
Fig. 7 is the circuit theory diagrams of the USB type C interface protection circuit of the present invention；
Fig. 8 is the workflow diagram of the present invention；
Fig. 9 is the software flow pattern of the present invention.
Detailed description of the invention
Embodiments of the invention are described below in detail, and the example of described embodiment is shown in the drawings, the most from start to finish
Same or similar label represents same or similar element or has the element of same or like function.Below with reference to attached
The embodiment that figure describes is exemplary, it is intended to is used for explaining the present invention, and is not considered as limiting the invention.
The present invention provides a kind of intelligence Wicresoft blood glucose continuous monitor system, with reference to attached Fig. 1 and 2, including: sensor probe 1,
Monitoring terminal 2；Sensor probe 1 connects monitoring terminal 2；Also including shell 3, shell 3 is internal is provided with monitoring terminal 2, sensor
Probe 1 is inserted on shell 3.Shell 3 surface is additionally provided with system run indicator 4 and bluetooth connects display lamp 5, and system is run and referred to
Show that lamp 4 and bluetooth connect display lamp 5 and connect the button in monitoring terminal 2 and LED display circuit respectively.The side of shell 3 is also pacified
Dress USB interface 2011.
Wherein, monitoring terminal 2 and shell 3 can be reused, and sensor probe 1 is for user's first use, a monitoring
Periodic process terminates, and sensor probe 1 can disassemble from pedestal, if reused, is filled by USB charge port
After electricity, changing new sensor probe 1 can reuse.System run indicator 4 and bluetooth connect display lamp 5 and can show and fill
Electricity and system running state and bluetooth connect instruction state.
It is specifically described below:
Sensor probe 1 is for monitoring the blood sugar concentration of human body；
Thrusting wound and patient pain to improve sensitivity, reduction response time reduction, sensor probe 1 uses list
Pin glucose sensor, the grinding section part coating a thin layer electrically insulating silicone rubber of sensor probe 1, the semicircle of needle point will be arranged on
Working electrode on groove is fixed with auxiliary electrode, and working electrode and auxiliary electrode are covered in Ag/AgC1 reference electrode two respectively
Side.Single needle structure is used to be possible not only to reduce the thorn people's wound to human body and sensation of pricking further, and because being greatly reduced electrode
Spacing and improve sensitivity, reduce response time.Three-electrode system may make up differential configuration, it is possible to effectively gets rid of some
The interference of internal electric active matter confrontation sensor, is conducive to improving anti-interference.
Single needle type glucose sensor thrusts subcutaneous, and single needle type glucose sensor is to realize Fructus Vitis viniferae based on enzymatic reaction
The Electrochemical Detection of sugar.Glucose can be generated glucose by oxygen molecule oxidation under the catalytic action of glucoseoxidase (GOD)
Acid and hydrogen peroxide (H2O2), and there is between H2O2 concentration and concentration of glucose to be measured strict stoichiometric relationship.Pass through
The generation amount of electrical way measurement H2O2 can obtain the concentration information of glucose to be measured.
First, thrusting subcutaneous by single needle sensor, the chemical equation occurred at enzyme membrane layer is:
β-D-Glucose+O2----→ maltonic acid+H202
Under certain potentials, Pt metal has catalyticing decomposition action to H202, and the reaction equation occurred at electrode is
H202----→02+2H++2e-
The electric charge produced is transferred to enzyme electrode and can be formed electric current, and size of current is proportional with H202 concentration, such that it is able to
Go out the relation of itself and concentration of glucose.
Then, utilize monitoring terminal 2 to measure blood sugar for human body value in real time, and blood glucose value is wirelessly transferred (bluetooth or WIFI)
To mobile terminal (mobile phone A PP) or computer terminal；Can reach to measure in real time the purpose of blood glucose.
As it is shown on figure 3, monitoring terminal 2 includes core system 202, frontend amplifying circuit 203, power circuit 204, standby electricity
Cell system 205, button and LED display circuit 206, usb circuit 201；
The sensor input connection probe 1 of frontend amplifying circuit 203, the output termination kernel of frontend amplifying circuit 203
System 202, power circuit 204 connects the power end of core system 202, and battery backup system 205 connects the power supply of core system 202
End, the outfan of core system 202 is connected with button and LED display circuit 206, usb circuit 201 respectively, core system
202 wireless connections mobile terminal or computer terminals.
Core system 202 selects the microprocessor nRf51822 integrating bluetooth communication of SOC structure.This chip has
Bluetooth communication chip and 32 kernel integral structures, can be connected by bluetooth and mobile terminal (mobile phone A PP) or computer terminal
Connecing, smart machine APP interconnects with cloud platform server, and server uses Ali's Cloud Server.When monitoring terminal is connected to cloud clothes
After business device, user or medical monitoring personnel can utilize the browser net of mobile phone or computer end anywhere at any time
The monitoring terminal of user side is managed and checks and analyze by page, and the physiological feature signal that dynamic web page demonstrates can conduct
The foundation of diagnosis.This system combines remote medical monitor with embedded system, can design data acquisition accurately, fortune
Safe and reliable, the wireless remote medical treatment monitoring system of feature richness of row.
Fig. 4 is the circuit theory diagrams of core system.
NRF51822 is a Bluetooth chip with ARM Cortex-M0 as core, wherein Cortex-M0 processor based on
One high integration, 32 bit processor kernels of low-power consumption, use 3 level production line von Karman structure (Von
Neumann architecture).By the design of simple, powerful instruction set and optimization comprehensively, (offer includes one
Individual monocycle multiplier is at interior high-end process hardware), Cortex-M0 processor can realize high efficiency.
NRF51822 chip major function includes:
1, flash memory and 16kB RAM on 256kB sheet；
2, numeral and mixed signal periphery, including SPI, 2-wire, ADC and quadrature decoder；
3, PI passage；
When 4, joining LDO on sheet power range be 1.8-3.6V, LDO bypass mode be 1.75-1.95V；
5, on sheet, drop-down DC/DC transducer is used for 3V battery (such as, button cell)；
6, apply in Bluetooth Low Energy, be not required to outside 32kHz crystal, escapable cost and circuit board space；
7,6x6mm 48 foot QFN encapsulation, it is provided that at most up to 32 GPIO；
8, complete bluetooth protocol stack (to the linking layer of configuration file).
9, the S110 of nRF51822 be can download, royalty-free, precompile binary system Bluetooth Low Energy storehouse, can be independently programmable
And renewal.Function includes:
10, the asynchronous and API of event-driven SVC；
Protection when 11, running；
12, GATT, GAP and L2CAP rank API；
13, periphery and broadcasting equipment role；
14, GATT client and server；
The non-parallel multi-protocols operation of 15 and 2.4GHz RF specialized protocols；
16, the code less than 128kB and the RAM of 6kB, leaves the flash memory more than 128kB and 10kB for application program
RAM；
17, compared with the dual chip application using previous generation nRF8001, the nRF51822 running S110 storehouse reduces height
Reach the power consumption of 50%.
18, S110 storehouse and nRF51822 cooperate plus nRF518SDK, and nRF518 comprises comprehensive Bluetooth Low Energy
Configuration file, service and example set of applications.
It is 450m by external diameter and surface has sputtered 20nm/200nm thickness Ti/Pt thin film that sensor probe thrusts the part of skin
Rustless steel empty micropin fixing within the molds, grind micropin by mould along the direction with needle tubing axis parallel, until mill
Till removing 1/2 needle tubing.First it is fixed with on needle point in the working electrode of GOD and the semicircle groove of auxiliary electrode and grinds section
Place is respectively coated with a thin layer electrically insulating silicone rubber, then working electrode and auxiliary electrode is covered in Ag/AgC1 reference electrode respectively
Both sides, and it is put in cold curing 24h in clean culture dish.The insulation asked of each electrode is completed by the electrically insulating silicone rubber coated, and treats
After being fully cured, at micropin rear end lead-in wire in case test uses.
Free electron can be produced in blood at enzyme electrode.Owing to electrode two ends exist driving voltage, just have orientation electricity
Stream flows through electrode.This driving voltage is that the 1.5V voltage stabilizing provided by ADC is produced by electric resistance partial pressure, about exists
About 300mV, it can produce directional current.Due to the measurement of A/D modular converter is voltage, so needing to turn this directional current
Change voltage into, and carry out certain amplification.
Native system uses the frontend amplifying circuit shown in Fig. 5 to realize electric current to the conversion of voltage and amplification.
In Fig. 5, frontend amplifying circuit uses the amplifier of MAX4225 model.
Power circuit selects the chip of TPS62260 model as system DC-DC switching power supply, provides steady for system
Determining DC voltage, selecting BQ24040 is lithium cell charging chip.
Battery backup system selects S-8211CCU as battery discharge protection chip.
Usb circuit includes USB type C interface protection circuit and USB type C interface circuit, USB type C
Interface protective circuit connects USB type C interface circuit, and USB type C interface circuit includes USB interface.
Fig. 6 is the circuit theory diagrams of USB type C interface circuit.
Fig. 7 is the circuit theory diagrams of USB type C interface protection circuit.
Button and LED display circuit, button is responsible for start and wireless connections operation, the operation of LED display circuit control system
Display lamp and bluetooth connect display lamp, it is provided that run and connect instruction.
The intelligent Wicresoft blood glucose continuous monitor system of the present invention is portable hardware configuration, rational hardware circuit design
It it is the basis of product stable operation.According to the functional requirement of bracelet, design Embedded ware circuit and the most embedding
Enter formula c program.System uses the high performance chips of low-power consumption to combine discrete component, and embedded hardware circuit is with high performance ARM
32 Cortex-M0 family chips are as CPU, and this chip is MCU+BLE integration SOC structure, in conjunction with necessary single needle sensing
Device and amplifying circuit, peripheral hardware circuit, voltage stabilizing and charging circuit and protection circuit etc., jointly realize sampling, data interaction
Etc. function
The intelligent Wicresoft blood glucose continuous monitor system of the present invention, in programming, uses the MDK of KEIL company to compile
Journey.
Keil C is the Single Chip C Language software development system that Keil Software company of the U.S. produces, with compilation phase
Ratio, C language functionally, structural, readable, maintainable on have obvious advantage, thus be easy to learn and use.With crossing compilation language
Re-use C after speech to develop, know from experience more deep.
Keil C51 software provides abundant built-in function and powerful Integrated Development debugging acid, full Windows circle
Face.Additionally the important point, as long as the assembly code generated after having a look compiling, just can realize the target generation that Keil C generates
Code efficiency is the highest, and the assembly code that most statements generate is the compactest, it is readily appreciated that.More can embody when developing large software
The advantage of high-level language.
Intelligence Wicresoft blood glucose continuous monitor system possesses blood sugar test, data send and receives, and sends emergency warning information
Etc. function, as shown in Figure 8 and Figure 9.In programming, embedded type C language is used to be designed.
In order to realize these functions, whole system can be divided into following several pattern: park mode, sensor test blood
Sugar pattern.Park mode is arranged for realizing low-power consumption.System is not when detecting blood glucose and when not having host computer to call
Just entering park mode, now nRF51822 system is in low power consumpting state, and the power supply of other peripheral components is cut off, whole system
The power consumption of system is down to minimum；Test blood glucose pattern is when intervalometer needs to carry out blood sugar test or when host computer wakes up up
The pattern that blood glucose meter is entered.In this mode, system will detect sensor voltage, and trip temperature of going forward side by side compensates, and then give hemorrhage
Sugar concentration value measurement result；User can be become by the average blood sugar in smart mobile phone inquiry random time section and change of blood sugar
Gesture, in order to patient takes correctly taking drugs mode.In order to reach the purpose of low-power consumption, utilizing battery more fully, native system also has
Having sleeping function automatically, when user stops operation more than 20s, no matter under which pattern, system all can auto-returned dormancy mould
Formula.
Measure after terminating every time, data will be turned to report and report to the police subprogram.First by measurement result and warning bound
Value compares, as do not transfinited, then and normal transmission testing result；As out-of-limit, then start warning, and export measurement result and out-of-limit carry
Show symbol.
C language subprogram is as follows:
The intelligent Wicresoft blood glucose continuous monitor system of the present invention is a kind of based on mobile Internet, novel towards family
Blood sugar monitoring instrument, it can provide the user continual, long-time blood sugar monitoring, and user wears in arm so that user lives
Dynamic space is bigger, improve the convenience of blood glucose monitoring.Acupuncture type blood sampling formula blood glucose meter can be replaced completely, owing to moving in recent years
Dynamic network and the fast development of microelectric technique, the condition of embedded technology application reaches its maturity so that blood sugar monitoring has had more preferably
Solution.Embedded technology have the prominent advantages that low cost, volume are little, application is flexible.
Intelligent Wicresoft blood glucose monitoring system integrated application wireless Internet transmission technology that the design makes and embedded
System designs, and obtains patient's moving in the case of normal activity with bigger freedom of movement can to the patient needing blood sugar monitoring
State blood glucose signal.Embedded technology is used to transmit blood glucose level data to mobile phone system with relatively low cost by wireless Internet technologies
System, can achieve long-range blood glucose by mobile phone A PP and guard, and no longer has a harsh requirement to the position at patient place, effective gram
Take the shortcoming that existing common blood glucose monitoring system cannot be networked.
The present invention attempts to be realized the length of the blood glucose level data of substantial amounts of high-risk group by mobile Internet+cloud database platform
Phase storage and accumulation, play good assosting effect for the medication of patient and treatment, equally, for China set up one general
The big data platform in the Internet blood glucose basis play a good start.
Although above it has been shown and described that embodiments of the invention, it is to be understood that above-described embodiment is example
Property, it is impossible to be interpreted as limitation of the present invention, those of ordinary skill in the art is without departing from the principle of the present invention and objective
In the case of above-described embodiment can be changed within the scope of the invention, revise, replace and modification.The scope of the present invention
Extremely it is equal to by claims and limits.
Claims (10)
1. an intelligent Wicresoft blood glucose continuous monitor system, it is characterised in that including: sensor probe, monitoring terminal；Described biography
Sensor probe connects described monitoring terminal；
Described sensor probe is for monitoring the blood sugar concentration of human body；
Described monitoring terminal measures blood sugar for human body value in real time, and blood glucose value is wirelessly transmitted to mobile terminal or computer eventually
End；
Described monitoring terminal includes that core system, frontend amplifying circuit, power circuit, battery backup system, button and LED show
Circuit, usb circuit；
The input of described frontend amplifying circuit connects described sensor probe, and the output termination of described frontend amplifying circuit is described
Core system, described power circuit connects the power end of described core system, and described battery backup system connects described core system
Power end, the outfan of described core system is connected with button and LED display circuit, usb circuit respectively, described kernel system
System wireless connections mobile terminal or computer terminal.
2. intelligence Wicresoft as claimed in claim 1 blood glucose continuous monitor system, it is characterised in that: also include shell, described outside
Being provided with monitoring terminal inside shell, described sensor probe is inserted on shell.
3. intelligence Wicresoft as claimed in claim 2 blood glucose continuous monitor system, it is characterised in that: described case surface is additionally provided with
System run indicator and bluetooth connect display lamp, described system run indicator and described bluetooth connection display lamp and connect respectively
Described button and LED display circuit.
4. intelligence Wicresoft as claimed in claim 2 blood glucose continuous monitor system, it is characterised in that: the side of described shell is also pacified
Dress USB interface.
5. intelligence Wicresoft as claimed in claim 1 blood glucose continuous monitor system, it is characterised in that: described core system selects collection
The microprocessor nRf51822 that bluetooth communication is integrated.
6. intelligence Wicresoft as claimed in claim 1 blood glucose continuous monitor system, it is characterised in that: described frontend amplifying circuit is adopted
Amplifier by MAX4225 model.
7. intelligence Wicresoft as claimed in claim 1 blood glucose continuous monitor system, it is characterised in that: grinding of described sensor probe
Mill section part coating a thin layer electrically insulating silicone rubber, the working electrode on the semicircle groove being arranged on needle point is solid with auxiliary electrode
Fixed, working electrode and auxiliary electrode are covered in Ag/AgC1 reference electrode both sides respectively.
8. intelligence Wicresoft as claimed in claim 1 blood glucose continuous monitor system, it is characterised in that: described power circuit is selected
The chip of TPS62260 model is as system DC-DC switching power supply, and selecting BQ24040 is lithium cell charging chip.
9. intelligence Wicresoft as claimed in claim 1 blood glucose continuous monitor system, it is characterised in that: described battery backup system is selected
With S-8211CCU as battery discharge protection chip.
10. intelligence Wicresoft as claimed in claim 1 blood glucose continuous monitor system, it is characterised in that: described usb circuit bag
Including USB type C interface protection circuit and USB type C interface circuit, described USB type C interface protection circuit connects
USB type C interface circuit.
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| CN109907763A (en) * | 2017-12-12 | 2019-06-21 | 研能科技股份有限公司 | Blood sugar detection device |
| CN113892948A (en) * | 2021-09-30 | 2022-01-07 | 南京康博智慧健康研究院有限公司 | A smart blood sugar monitoring watch and working method |
| CN115397313A (en) * | 2020-01-23 | 2022-11-25 | 威孚姆技术公司 | Auxiliary Data for Improving the Performance of Continuous Glucose Monitoring Systems |
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