CN106204623B - More contrast image synchronizations are shown and the method and device of positioning and demarcating - Google Patents

Abstract

The invention discloses a method and device for synchronously displaying and positioning calibration of multi-contrast images, wherein the method includes: obtaining multiple contrast images of the same part of a living body; performing scanning position information extraction and comparison calculation on the multiple contrast images; According to the position comparison results on the multiple contrast images, the multiple contrast images are displayed synchronously in sub-windows; the window where the real mouse pointer is located is used as the target window, and according to the position of the mouse pointer on the target window image and the multiple contrasts Comparing the position on the image, calculate the corresponding position on other window images and display the virtual mouse pointer at this position. The invention can realize synchronously displaying multiple contrast images and synchronously positioning and marking position information in multiple windows.

Description

Method and device for synchronous display and positioning calibration of multi-contrast images

technical field

The invention relates to the technical field of medical clinical imaging, in particular to a method and device for synchronous display and positioning calibration of multi-contrast images.

Background technique

With the development of clinical image diagnosis technology, in order to improve the accuracy of disease diagnosis, clinical doctors often diagnose and analyze diseases by analyzing images of various contrasts. For the diagnosis of a certain part of the disease, sometimes the same imaging modality is used, such as computerized tomography (Computed Tomography, CT), magnetic resonance imaging (Magnetic Resonance Imaging, MRI), ultrasound imaging (Ultrasound, US) and positron imaging. Emission computed tomography (Positron Emission Computed Tomography, PET), etc., using one imaging modality to obtain several images with different contrasts, and then making a diagnosis according to the appearance of the lesion in different contrast images; sometimes combining multiple imaging modalities The advantages of using a variety of imaging modalities to diagnose diseases, such as PET/CT is a combination of positron emission tomography and electronic computer tomography, PET/MRI is a combination of positron emission tomography and magnetic resonance imaging, etc. . The obtained medical images generally comply with the DICOM (Digital Imaging and Communication in Medicine) standard, which includes all information exchange protocols for medical digital image collection, archiving, communication, display, and query.

At present, when doctors perform multi-contrast image diagnosis, they often need to switch between multiple contrast images, or display them on multiple screens, and then compare them with the naked eye, or manually select the same position of each image for comparison. This method is not only very inefficient but also difficult to perform accurate comparison, especially the comparison of high-resolution images, which adds additional difficulty to doctors, and it is difficult to accurately select the same position for comparison.

Contents of the invention

An embodiment of the present invention provides a method for synchronous display and positioning calibration of multi-contrast images, so as to realize synchronous display of multiple contrast images and synchronous positioning and calibration position information in multiple windows. The method includes:

Obtain multiple contrast images of the same part of the organism;

performing scanning position information extraction and comparison calculation on the multiple contrast images;

The scanning position information extraction and comparison calculation of multiple contrast images includes

Preprocessing the scanning position information of multiple contrast images, so that multiple contrast images have the same scanning layer position information and scanning layer position information,

Extracting the position information of the scanning layer and the position information of the scanning layer of the various contrast images, and comparing and calculating the deviation;

The preprocessing of the scanning position information of the various contrast images includes: checking whether the various contrast images have scanning position deviations, and performing multi-window synchronous display of the various contrast images when the various contrast images do not have scanning position deviations, When multiple contrast images have scanning position deviations, perform registration calculations on multiple contrast images, calculate position deviations of multiple contrast images, and perform multi-window synchronous processing on multiple contrast images;

Synchronously displaying the multiple contrast images in windows according to the position comparison results on the multiple contrast images, including; if the position comparison results on the multiple contrast images indicate the scan levels of the multiple contrast images If the position information is different, according to the scanning layer number and scanning layer thickness of the target window image, the scanning layer thickness of other window images, and the scanning position deviation between other window images and the target window image, find the adjacent layers of other window images and display them synchronously;

Taking the window where the real mouse pointer is located as the target window, according to the mouse pointer position on the target window image and the position comparison results on the multiple contrast images, calculate the corresponding position on other window images and display the virtual mouse pointer at this position.

In one embodiment, the adjacent levels of other window images are searched for and displayed synchronously according to the following formula:

N _x =Round[(ΔZ _x +M x S)/S _x ];

Among them, N _X is the adjacent layer of other window images, ΔZ _X is the scanning position deviation between other window images and the target window image; M is the number of scanning layers of the target window image; S is the scanning layer thickness of the target window image; S _X is The scanning layer thickness of other window images; Round[] means rounding calculation.

In one embodiment, according to the mouse pointer position on the target window image and the position comparison results on the multiple contrast images, calculate the corresponding position on other window images and display the virtual mouse pointer at this position, including:

If the position comparison results on the multiple contrast images show that the position information in the scanning layer of the multiple contrast images is different, then according to the position of the mouse pointer on the target window image, and the intra-layer position deviation between other window images and the target window image , calculate the corresponding position on other window images and display the virtual mouse pointer at this position.

In one embodiment, the corresponding position on other window images is calculated according to the following formula and the virtual mouse pointer is displayed at this position:

(X ₁ ,Y ₁ )=(X+ΔX ₁ ,Y+ΔY ₁ );

Among them, (X ₁ , Y ₁ ) is the corresponding position on other window images, (X, Y) is the position of the mouse pointer on the target window image, (ΔX ₁ , ΔY ₁ ) is the intralayer position of other window images and the target window image deviation.

In one embodiment, the method also includes:

According to the operation done by the mouse pointer on the image of the target window, the operation results are displayed synchronously in other windows.

The embodiment of the present invention also provides a multi-contrast image synchronous display and positioning and calibration device, which is used to realize synchronous display of multiple contrast images and synchronous positioning and calibration position information in multiple windows. The device includes:

The image acquisition module is used to obtain multiple contrast images of the same part of the organism;

A position comparison module, configured to perform scanning position information extraction and comparison calculation on the various contrast images;

The position comparison module is further used to: preprocess the scanning position information of various contrast images, so that the various contrast images have the same scanning layer position information and scanning layer position information,

Extracting the position information of the scanning layer and the position information of the scanning layer of the various contrast images, and comparing and calculating the deviation;

The preprocessing of the scanning position information of the various contrast images includes: checking whether the various contrast images have scanning position deviations, and performing multi-window synchronous display of the various contrast images when the various contrast images do not have scanning position deviations, When multiple contrast images have scanning position deviations, perform registration calculations on multiple contrast images, calculate position deviations of multiple contrast images, and perform multi-window synchronous processing on multiple contrast images;

An image display module, configured to synchronously display the multiple contrast images in windows according to the position comparison results on the multiple contrast images, including: if the position comparison results on the multiple contrast images indicate that the multiple If the scanning layer position information of two kinds of contrast images is different, then according to the scanning layer number and scanning layer thickness of the target window image, the scanning layer thickness of other window images, and the scanning position deviation between other window images and the target window image, find the location of other window images. Adjacent to the level and displayed synchronously;

The positioning calibration module is used to use the window where the real mouse pointer is located as the target window, calculate the corresponding position on other window images and display at this position according to the mouse pointer position on the target window image and the position comparison results on the multiple contrast images Virtual mouse pointer.

In one embodiment, the image display module is further configured to search for adjacent levels of other window images and display them synchronously according to the following formula:

N _x =Round[(ΔZ _x +M x S)/S _x ];

Among them, N _X is the adjacent layer of other window images, ΔZ _X is the scanning position deviation between other window images and the target window image; M is the number of scanning layers of the target window image; S is the scanning layer thickness of the target window image; S _X is The scanning layer thickness of other window images; Round[] means rounding calculation.

In one embodiment, the positioning calibration module is further used for:

If the position comparison results on the multiple contrast images show that the position information in the scanning layer of the multiple contrast images is different, then according to the position of the mouse pointer on the target window image, and the intra-layer position deviation between other window images and the target window image , calculate the corresponding position on other window images and display the virtual mouse pointer at this position.

In one embodiment, the positioning calibration module is further used to calculate the corresponding position on other window images according to the following formula and display the virtual mouse pointer at this position:

(X ₁ ,Y ₁ )=(X+ΔX ₁ ,Y+ΔY ₁ );

Among them, (X ₁ , Y ₁ ) is the corresponding position on other window images, (X, Y) is the position of the mouse pointer on the target window image, (ΔX ₁ , ΔY ₁ ) is the intralayer position of other window images and the target window image deviation.

In one embodiment, the device also includes:

The operation synchronization module is used for synchronously displaying the operation results in other windows according to the operation performed by the mouse pointer on the image of the target window.

In the embodiment of the present invention, multiple contrast images are displayed synchronously in windows according to the position comparison results on the multiple contrast images, which avoids switching between multiple contrast images or displaying them on multiple screens; in the embodiment of the present invention According to the mouse pointer position on the target window image and the position comparison results on various contrast images, calculate the corresponding position on other window images and display the virtual mouse pointer at this position, avoiding the need for doctors to compare with the naked eye or manually select the same image for each image Positions are compared; the implementation process of the embodiment of the present invention is simple and efficient, and can easily achieve accurate comparison, even if it is a comparison of high-resolution images, it will not add additional difficulty to the doctor.

Description of drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings that need to be used in the description of the embodiments will be briefly introduced below. Obviously, the drawings in the following description are only some embodiments of the present invention. For those skilled in the art, other drawings can also be obtained based on these drawings without creative effort. In the attached picture:

1 is a schematic diagram of a method for synchronously displaying and positioning a multi-contrast image in an embodiment of the present invention;

Fig. 2 is a specific example diagram of multi-contrast image synchronous display and positioning calibration in the embodiment of the present invention;

3 is a schematic diagram of multi-window display of different data sources without scanning position deviation in an embodiment of the present invention;

Fig. 4 is a schematic diagram of multi-window display of an image source with layer deviation in an embodiment of the present invention;

Fig. 5 is a schematic diagram of display layer calculation when there is layer deviation in the embodiment of the present invention;

Fig. 6 is a schematic diagram of the synchronous positioning display of each window when there is an intra-layer position deviation in the embodiment of the present invention;

Fig. 7 is a schematic diagram of synchronous operation of each window in the embodiment of the present invention;

Fig. 8 is a schematic diagram of a device for synchronously displaying and positioning a multi-contrast image in an embodiment of the present invention;

FIG. 9 is a diagram of a specific example of a device for synchronously displaying and positioning a multi-contrast image in an embodiment of the present invention.

Detailed ways

In order to make the purpose, technical solutions and advantages of the embodiments of the present invention more clear, the embodiments of the present invention will be further described in detail below in conjunction with the accompanying drawings. Here, the exemplary embodiments and descriptions of the present invention are used to explain the present invention, but not to limit the present invention.

In order to realize synchronous display of multiple contrast images in multiple windows and accurate position synchronous calibration, an embodiment of the present invention provides a method for synchronous display of multiple contrast images and positioning calibration, as shown in Figure 1, the method may include:

Step 101, obtaining multiple contrast images of the same part of the organism;

Step 102, performing scanning position information extraction and comparison calculation on the various contrast images;

Step 103, displaying the multiple contrast images synchronously in windows according to the position comparison results on the multiple contrast images;

Step 104, using the window where the real mouse pointer is located as the target window, according to the mouse pointer position on the target window image and the position comparison results on the multiple contrast images, calculate the corresponding position on other window images and display the virtual mouse pointer at this position .

It can be known from the process shown in Figure 1 that in the embodiment of the present invention, multiple contrast images are displayed synchronously in windows according to the position comparison results on multiple contrast images, avoiding switching between multiple contrast images, or by Display on multiple screens; in the embodiment of the present invention, according to the mouse pointer position on the target window image and the position comparison results on multiple contrast images, calculate the corresponding position on other window images and display the virtual mouse pointer at this position, avoiding the doctor through Compare with the naked eye, or manually select the same position of each image for comparison; the implementation process of the embodiment of the present invention is simple and efficient, and can easily achieve accurate comparison. difficulty.

During specific implementation, multiple contrast images of the same part of the living body are obtained first. Multiple-contrast images can be obtained with clinical imaging techniques, which can be multiple scans from one imaging modality, such as magnetic resonance imaging (MRI) with transverse relaxation time-weighted images (T2WI) and longitudinal relaxation time-weighted images ( T1WI); or several sets of images from different imaging modalities, such as magnetic resonance images and positron emission tomography (PET). Multi-contrast images may also be referred to as multi-image data sources. As shown in Figure 2, each contrast image is used as an image source, and each image source can be unified into the same format, such as DICOM format, and the number of image sources can be increased or decreased at will according to clinical diagnosis needs.

After obtaining multiple contrast images of the same part of the living body, scan position information extraction and comparison calculation are performed on the multiple contrast images, and then the multiple contrast images are synchronized by windows according to the position comparison results on the multiple contrast images show. For example, in the example in Figure 1, since the medical image in DICOM format contains scanning position information, in order to facilitate the comparison of images with multiple windows at the same position, it is necessary to extract and compare the scanning position information of DICOM images from different image data sources . The scanning position information may include various information related to the scanning position. For example, in one embodiment, performing scanning position information extraction and comparison calculation on multiple contrast images may include extracting scan slice position information and scan intra-slice position information of multiple contrast images, and performing comparison to calculate deviation. The position information of the scanning layer may include the number of scanning layers and the thickness of the scanning layer.

In the example in Figure 2, medical images in DICOM format include all information such as image acquisition, archiving, communication, display, and query. As shown in Figure 2, first read the DICOM files of each image source, and preprocess the image scanning position information. When the scanning position information of each image source is the same, for example, multiple scanning protocols in magnetic resonance imaging use the The same positioning parameters, or simultaneous scans of multi-modal imaging (such as PET/MRI), etc., at this time, multiple data sources have the same scanning layer position information and scanning intra-layer position information. Through preprocessing, check whether the multi-data source has scanning position deviation in the X, Y or Z direction. If the multi-data source has no position deviation, the obtained image source can be directly imported into each window for comparison and display. The number of windows can be determined by the number of data sources, and the window size can be automatically optimized and adjusted on the display according to the number of windows. Fig. 3 is a schematic diagram of multi-window display of different data sources without scanning position deviation in the embodiment of the present invention. As shown in Fig. 3, three kinds of contrast image sources are displayed layer by layer in three image display windows, and the image sources displayed in each window are all In the same position, only the image contrast of each image signal source is different.

When the scanning position of each image source is not exactly the same, each image source will have a position deviation. The position deviation can be in the direction of the slice, that is, the Z direction, or it can be the position deviation within the slice, that is, the X, Y direction. In order to synchronize the images displayed in each window, it is necessary to perform registration calculations on each data source, and calculate the position deviation of each data source. This position deviation includes rigid deviations in the three directions of X, Y, and Z. Those skilled in the art are familiar with, The calculation of the position deviation can be realized by using a corresponding algorithm.

During specific implementation, multiple contrast images are displayed synchronously in different windows according to the position comparison results on the multiple contrast images, including: if the position comparison results on the multiple contrast images indicate that the scanning level position information of the multiple contrast images is different, then According to the scanning layer number and scanning layer thickness of the target window image, the scanning layer thickness of other window images, and the scanning position deviation between other window images and the target window image, find the adjacent layers of other window images and display them synchronously.

Fig. 4 is a schematic diagram of multi-window display of an image source with layer deviation in an embodiment of the present invention. As shown in Figure 4, when each data source has a position deviation, if the position deviation is in the Z direction of the layer, the layers displayed by the remaining windows are determined according to the layer where the target window stays. The target window can be any window, and the target window is determined according to the position of the real mouse pointer. As shown in Figure 4, the second window is defined as the target window. For the convenience of illustration, the second picture is shown as the target window in Figure 3-7, and any window can be selected as the target window in practical applications.

During specific implementation, the adjacent layers of other window images can be searched and displayed synchronously according to the following formula:

N _x =Round[(ΔZ _x +M x S)/S _x ];

Among them, N _X is the adjacent layer of other window images, ΔZ _X is the scanning position deviation between other window images and the target window image; M is the number of scanning layers of the target window image; S is the scanning layer thickness of the target window image; S _X is The scanning layer thickness of other window images; Round[] means rounding calculation.

In the example shown in FIG. 4 , it is assumed that the layer thicknesses of the image data source images are S ₁ , S ₂ , and S ₃ , and the positional deviations between the remaining windows 1 and 2 and the target window are ΔZ ₁ and ΔZ ₂ . Fig. 5 is a schematic diagram of display level calculation when there is a level deviation in the embodiment of the present invention. As shown in Fig. 5, when the target window stays at the M level, the remaining windows 1 and 2 will respectively stay at the level closest to the target window, namely : Round[(ΔZ ₁ +M×S ₂ )/S ₁ ] and Round[(ΔZ ₂ +M×S ₂ )/S ₃ ].

After multiple contrast images are displayed synchronously in sub-windows, according to the mouse pointer position on the target window image and the position comparison results on the multiple contrast images, calculate the corresponding positions on other window images and display the virtual mouse pointer at this position . In the example of FIG. 3 , the mouse pointers are all at the same position in multiple windows of different data sources without scanning position deviation.

In other embodiments, if the position comparison results on the multiple contrast images show that the position information in the scanning layer of the multiple contrast images is different, then according to the position of the mouse pointer on the target window image, and the layers of other window images and the target window image Calculate the corresponding position on other window images and display the virtual mouse pointer at this position. Fig. 6 is a schematic diagram of the synchronous positioning display of each window when there is a position deviation in the layer in the embodiment of the present invention. As shown in Fig. The position where the mouse pointer stays, calculates the positioning position of other window pointers.

Specifically, the corresponding position on other window images can be calculated according to the following formula and the virtual mouse pointer can be displayed at this position:

(X ₁ ,Y ₁ )=(X+ΔX ₁ ,Y+ΔY ₁ );

Among them, (X ₁ , Y ₁ ) is the corresponding position on other window images, (X, Y) is the position of the mouse pointer on the target window image, (ΔX ₁ , ΔY ₁ ) is the intralayer position of other window images and the target window image deviation.

In the example in Figure 6, assuming that the position deviation of the data source is in the X and Y directions, the position deviations of the other windows and the image source of the target window are (ΔX ₁ , ΔY ₁ ) and (ΔX ₂ , ΔY ₂ ), respectively. When the target When the mouse pointer of the window stays at (X _a , Y _b ), the mouse pointer corresponding to the image of the other window 1 stays at (X _a +ΔX ₁ ,Y _a +ΔY ₁ ), and the mouse pointer corresponding to the image of the other window 2 Stay at (X _a +ΔX ₂ , Y _a +ΔY ₂ ) position.

As shown in Figure 3 and Figure 6, when the real mouse pointer appears in a certain window (i.e. the target window), corresponding mouse pointers will also appear in other windows. This mouse pointer is a virtual mouse pointer, and can also be defined as other pointers , and the positions of the image data sources pointed by the mouse pointers in each sub-window are consistent. In short, the display of images from multiple data sources is synchronous, and position calibration can be performed synchronously. When the data source image of the target window changes, the other window images are automatically and synchronously displayed according to the position of the target window image, realizing synchronous comparison and display of multiple data source images. When the real mouse pointer stays on the data source of the target window, the mouse pointer will also appear at the same image position in other windows.

During specific implementation, the method in the embodiment of the present invention may further include: synchronously displaying the operation results in other windows according to the operation performed by the mouse pointer on the image of the target window. When any operation is performed on the data source image of the target window, other windows will also perform synchronous actions. When an operation is performed on the displayed image of a certain target window, such as a page turning operation, other windows also perform corresponding actions. When the sketch calculation operation is performed on the image of a certain target window, the other windows will also make the same action response at the corresponding position. Fig. 7 is a schematic diagram of synchronous operation of each window in the embodiment of the present invention. As shown in Figure 7, when various operations are performed on the image of the target window, such as delineating the region of interest, measuring the average value and variance of the signal in the region of interest, other windows will also be operated at the same position, and each image source has a position When there is a deviation, operate on the basis of the position deviation. This can provide synchronization of the data sources of each window, not only to turn pages synchronously, but also to accurately and synchronously locate the tissue positions of different windows, which is convenient for doctors to compare the performance of each image source corresponding to the same tissue position.

Based on the same inventive concept, an embodiment of the present invention also provides a device for synchronously displaying and positioning multi-contrast images, as described in the following embodiments. Since the problem-solving principle of the device is similar to the method for synchronous display of multi-contrast images and positioning calibration, the implementation of the device can refer to the implementation of the method for synchronous display of multi-contrast images and positioning calibration, and the repetition will not be repeated.

Fig. 8 is a schematic diagram of a device for synchronous display and positioning calibration of multi-contrast images in an embodiment of the present invention. The device can realize synchronous display and synchronous position calibration of multiple contrast images at the same position. As shown in Figure 8, the device may include:

An image obtaining module 801, configured to obtain multiple contrast images of the same part of the organism;

A position comparison module 802, configured to perform scanning position information extraction and comparison calculation on the various contrast images;

An image display module 803, configured to synchronously display the multiple contrast images in windows according to the position comparison results on the multiple contrast images;

The positioning calibration module 804 is used to use the window where the real mouse pointer is located as the target window, and calculate the corresponding position on other window images according to the position of the mouse pointer on the target window image and the position comparison results on the various contrast images and place the window at this position Displays the virtual mouse pointer.

During specific implementation, the position comparison module 802 may be further configured to: extract the position information of the scanning slice and the position information within the scan slice of the various contrast images, and compare and calculate the deviation.

During specific implementation, the image display module 803 can be further used for:

If the position comparison results on the multiple contrast images indicate that the scan layer position information of the multiple contrast images is different, then according to the number of scan layers and the scan layer thickness of the target window image, the scan layer thickness of other window images, and The scanning position deviation between other window images and the target window image, find the adjacent layers of other window images and display them synchronously.

During specific implementation, the image display module 803 can be further used to search for adjacent levels of other window images and display them synchronously according to the following formula:

N _x =Round[(ΔZ _x +M x S)/S _x ];

Among them, N _X is the adjacent layer of other window images, ΔZ _X is the scanning position deviation between other window images and the target window image; M is the number of scanning layers of the target window image; S is the scanning layer thickness of the target window image; S _X is The scanning layer thickness of other window images; Round[] means rounding calculation.

During specific implementation, the positioning calibration module 804 can be further used to:

If the position comparison results on the multiple contrast images show that the position information in the scanning layer of the multiple contrast images is different, then according to the position of the mouse pointer on the target window image, and the intra-layer position deviation between other window images and the target window image , calculate the corresponding position on other window images and display the virtual mouse pointer at this position.

During specific implementation, the positioning calibration module 804 can be further used to calculate the corresponding position on other window images according to the following formula and display the virtual mouse pointer at this position:

(X ₁ ,Y ₁ )=(X+ΔX ₁ ,Y+ΔY ₁ );

Among them, (X ₁ , Y ₁ ) is the corresponding position on other window images, (X, Y) is the position of the mouse pointer on the target window image, (ΔX ₁ , ΔY ₁ ) is the intralayer position of other window images and the target window image deviation.

FIG. 9 is a diagram of a specific example of a device for synchronously displaying and positioning a multi-contrast image in an embodiment of the present invention. As shown in Figure 9, in this example, the device shown in Figure 8 may also include:

The operation synchronization module 901 is used for synchronously displaying the operation results in other windows according to the operation performed by the mouse pointer on the image of the target window.

To sum up, in the embodiment of the present invention, multiple contrast images are synchronously displayed in windows according to the position comparison results on the multiple contrast images, which avoids switching between multiple contrast images or displaying them on multiple screens; In the embodiment of the present invention, according to the mouse pointer position on the target window image and the position comparison results on various contrast images, the corresponding position on other window images is calculated and the virtual mouse pointer is displayed at this position, which avoids the doctor from making a comparison with the naked eye, or Manually select the same position of each image for comparison; the implementation process of the embodiment of the present invention is simple and efficient, and can easily achieve accurate comparison, even if it is a comparison of high-resolution images, no additional difficulty will be added to the doctor.

Furthermore, the embodiment of the present invention also provides the synchronization of data sources of each window, which not only can turn pages synchronously, but also accurately and synchronously locate the tissue positions of different windows, so that doctors can compare the performance of each image source corresponding to the same tissue position. In conclusion, the embodiment of the present invention provides a solution for multi-window diagnosis, comparison and measurement.

Those skilled in the art should understand that the embodiments of the present invention may be provided as methods, systems, or computer program products. Accordingly, the present invention can take the form of an entirely hardware embodiment, an entirely software embodiment, or an embodiment combining software and hardware aspects. Furthermore, the present invention may take the form of a computer program product embodied on one or more computer-usable storage media (including but not limited to disk storage, CD-ROM, optical storage, etc.) having computer-usable program code embodied therein.

The present invention is described with reference to flowchart illustrations and/or block diagrams of methods, apparatus (systems), and computer program products according to embodiments of the invention. It should be understood that each procedure and/or block in the flowchart and/or block diagram, and a combination of procedures and/or blocks in the flowchart and/or block diagram can be realized by computer program instructions. These computer program instructions may be provided to a general purpose computer, special purpose computer, embedded processor, or processor of other programmable data processing equipment to produce a machine such that the instructions executed by the processor of the computer or other programmable data processing equipment produce a An apparatus for realizing the functions specified in one or more procedures of the flowchart and/or one or more blocks of the block diagram.

These computer program instructions may also be stored in a computer-readable memory capable of directing a computer or other programmable data processing apparatus to operate in a specific manner, such that the instructions stored in the computer-readable memory produce an article of manufacture comprising instruction means, the instructions The device realizes the function specified in one or more procedures of the flowchart and/or one or more blocks of the block diagram.

These computer program instructions can also be loaded onto a computer or other programmable data processing device, causing a series of operational steps to be performed on the computer or other programmable device to produce a computer-implemented process, thereby The instructions provide steps for implementing the functions specified in the flow chart or blocks of the flowchart and/or the block or blocks of the block diagrams.

The specific embodiments described above have further described the purpose, technical solutions and beneficial effects of the present invention in detail. It should be understood that the above descriptions are only specific embodiments of the present invention and are not intended to limit the scope of the present invention. Protection scope, within the spirit and principles of the present invention, any modification, equivalent replacement, improvement, etc., shall be included in the protection scope of the present invention.

Claims (10)

1. A method for multi-contrast image synchronous display and positioning calibration, characterized in that, comprising: Obtain multiple contrast images of the same part of the organism; performing scanning position information extraction and comparison calculation on the multiple contrast images; The scanning position information extraction and comparison calculation for multiple contrast images includes: Preprocessing the scanning position information of multiple contrast images, so that multiple contrast images have the same scanning layer position information and scanning layer position information, Extracting the position information of the scanning layer and the position information of the scanning layer of the various contrast images, and comparing and calculating the deviation; The preprocessing of the scanning position information of the various contrast images includes: checking whether the various contrast images have scanning position deviations, and performing multi-window synchronous display of the various contrast images when the various contrast images do not have scanning position deviations, When multiple contrast images have scanning position deviations, perform registration calculations on multiple contrast images, calculate position deviations of multiple contrast images, and perform multi-window synchronous processing on multiple contrast images; Synchronously displaying the multiple contrast images in windows according to the position comparison results on the multiple contrast images, including; if the position comparison results on the multiple contrast images indicate the scan levels of the multiple contrast images If the position information is different, according to the scanning layer number and scanning layer thickness of the target window image, the scanning layer thickness of other window images, and the scanning position deviation between other window images and the target window image, find the adjacent layers of other window images and display them synchronously; Taking the window where the real mouse pointer is located as the target window, according to the mouse pointer position on the target window image and the position comparison results on the multiple contrast images, calculate the corresponding position on other window images and display the virtual mouse pointer at this position. 2. The method according to claim 1, characterized in that, the adjacent layers of other window images are searched for and displayed synchronously according to the following formula: N _x =Round[(ΔZ _x +M x S)/S _x ]; Among them, N _X is the adjacent layer of other window images, ΔZ _X is the scanning position deviation between other window images and the target window image; M is the number of scanning layers of the target window image; S is the scanning layer thickness of the target window image; S _X is The scanning layer thickness of other window images; Round[] means rounding calculation. 3. The method according to claim 1, wherein, according to the mouse pointer position on the target window image and the position comparison results on the multiple contrast images, calculate the corresponding position on other window images and display the virtual mouse at this position pointers, including: If the position comparison results on the multiple contrast images show that the position information in the scanning layer of the multiple contrast images is different, then according to the position of the mouse pointer on the target window image, and the intra-layer position deviation between other window images and the target window image , calculate the corresponding position on other window images and display the virtual mouse pointer at this position. 4. The method according to claim 3, characterized in that, the corresponding positions on other window images are calculated according to the following formula and the virtual mouse pointer is displayed at this position: (X ₁ ,Y ₁ )=(X+ΔX ₁ ,Y+ΔY ₁ ); Among them, (X ₁ , Y ₁ ) is the corresponding position on other window images, (X, Y) is the position of the mouse pointer on the target window image, (ΔX ₁ , ΔY ₁ ) is the intralayer position of other window images and the target window image deviation. 5. The method according to any one of claims 1 to 4, further comprising: According to the operation done by the mouse pointer on the image of the target window, the operation results are displayed synchronously in other windows. 6. A device for synchronously displaying and positioning a multi-contrast image, characterized in that it comprises: The image acquisition module is used to obtain multiple contrast images of the same part of the organism; A position comparison module, configured to perform scanning position information extraction and comparison calculation on the various contrast images; The position comparison module is further used to: preprocess the scanning position information of various contrast images, so that the various contrast images have the same scanning layer position information and scanning layer position information, Extracting the position information of the scanning layer and the position information of the scanning layer of the various contrast images, and comparing and calculating the deviation; The preprocessing of the scanning position information of the various contrast images includes: checking whether the various contrast images have scanning position deviations, and performing multi-window synchronous display of the various contrast images when the various contrast images do not have scanning position deviations, When multiple contrast images have scanning position deviations, perform registration calculations on multiple contrast images, calculate position deviations of multiple contrast images, and perform multi-window synchronous processing on multiple contrast images; An image display module, configured to synchronously display the multiple contrast images in windows according to the position comparison results on the multiple contrast images, including: if the position comparison results on the multiple contrast images indicate that the multiple If the scanning layer position information of two kinds of contrast images is different, then according to the scanning layer number and scanning layer thickness of the target window image, the scanning layer thickness of other window images, and the scanning position deviation between other window images and the target window image, find the location of other window images. Adjacent to the level and displayed synchronously; The positioning calibration module is used to use the window where the real mouse pointer is located as the target window, calculate the corresponding position on other window images and display at this position according to the mouse pointer position on the target window image and the position comparison results on the multiple contrast images Virtual mouse pointer. 7. The device according to claim 6, wherein the image display module is further used to search for adjacent layers of other window images and display them synchronously according to the following formula: N _x =Round[(ΔZ _x +M x S)/S _x ]; Among them, N _X is the adjacent layer of other window images, ΔZ _X is the scanning position deviation between other window images and the target window image; M is the number of scanning layers of the target window image; S is the scanning layer thickness of the target window image; S _X is The scanning layer thickness of other window images; Round[] means rounding calculation. 8. The device according to claim 6, wherein the positioning and calibration module is further used for: If the position comparison results on the multiple contrast images show that the position information in the scanning layer of the multiple contrast images is different, then according to the position of the mouse pointer on the target window image, and the intra-layer position deviation between other window images and the target window image , calculate the corresponding position on other window images and display the virtual mouse pointer at this position. 9. The device according to claim 8, wherein the positioning calibration module is further used to calculate the corresponding position on other window images according to the following formula and display the virtual mouse pointer at this position: (X ₁ ,Y ₁ )=(X+ΔX ₁ ,Y+ΔY ₁ ); Among them, (X ₁ , Y ₁ ) is the corresponding position on other window images, (X, Y) is the position of the mouse pointer on the target window image, (ΔX ₁ , ΔY ₁ ) is the intralayer position of other window images and the target window image deviation. 10. The device according to any one of claims 6 to 9, further comprising: The operation synchronization module is used for synchronously displaying the operation results in other windows according to the operation performed by the mouse pointer on the image of the target window.