CN106178256A - Intelligent gastrointestinal physical therapy device - Google Patents
Intelligent gastrointestinal physical therapy device Download PDFInfo
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- CN106178256A CN106178256A CN201610540262.6A CN201610540262A CN106178256A CN 106178256 A CN106178256 A CN 106178256A CN 201610540262 A CN201610540262 A CN 201610540262A CN 106178256 A CN106178256 A CN 106178256A
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- 238000000554 physical therapy Methods 0.000 title claims abstract description 124
- 230000002496 gastric effect Effects 0.000 title claims abstract description 87
- 230000000638 stimulation Effects 0.000 claims abstract description 40
- 230000000968 intestinal effect Effects 0.000 claims abstract description 6
- 230000000694 effects Effects 0.000 claims description 32
- 230000000737 periodic effect Effects 0.000 claims description 20
- 238000002560 therapeutic procedure Methods 0.000 claims description 16
- 238000013507 mapping Methods 0.000 claims description 9
- 230000007274 generation of a signal involved in cell-cell signaling Effects 0.000 claims description 6
- 235000012054 meals Nutrition 0.000 claims description 3
- 230000000291 postprandial effect Effects 0.000 claims description 3
- 238000011282 treatment Methods 0.000 abstract description 16
- 238000000034 method Methods 0.000 abstract description 12
- 210000002784 stomach Anatomy 0.000 abstract description 3
- 238000010586 diagram Methods 0.000 description 10
- 230000006870 function Effects 0.000 description 5
- 238000006467 substitution reaction Methods 0.000 description 3
- 230000005611 electricity Effects 0.000 description 2
- 238000011269 treatment regimen Methods 0.000 description 2
- 238000012795 verification Methods 0.000 description 2
- 201000004569 Blindness Diseases 0.000 description 1
- 208000018522 Gastrointestinal disease Diseases 0.000 description 1
- 238000009795 derivation Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000005714 functional activity Effects 0.000 description 1
- 230000005176 gastrointestinal motility Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/08—Arrangements or circuits for monitoring, protecting, controlling or indicating
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- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Electrotherapy Devices (AREA)
Abstract
The present invention relates to a kind of intelligent gastrointestinal physical therapy device, described device includes: collecting unit, and acquisition target Gastroenteric Electrical parameter before accepting interim physical therapy, described Gastroenteric Electrical parameter includes stomach electrical quantity and/or intestinal electrical quantity；Physiologic parameters signal generating unit, uses Gastroenteric Electrical parameter weighting described in many group weight coefficient sequence pair to sue for peace to generate corresponding multiple intermediate value netp, p=1 ..., N, N are the number of parameters in physiologic parameters, and based on each intermediate value netpGenerate corresponding physiologic parameters up；Electrical stimulation signal signal generating unit, based on physiologic parameters u1,…,uNGenerate electrical stimulation signal.By the Gastroenteric Electrical parameter of acquisition target, and using the weighted sum of Gastroenteric Electrical parameter as crucial intermediate value, generate physiologic parameters according to this key intermediate value, to apply physical therapy treatment targetedly.Said process is got involved substantially without doctor, can effectively reduce treatment cost, and can generate Physical therapy schemes pointedly.
Description
Technical Field
The invention relates to the field of biomedical electronic equipment, in particular to an intelligent gastrointestinal physiotherapy device.
Background
Gastrointestinal motility is necessarily accompanied by bioelectrical activity of the stomach and intestine, commonly referred to as "gastric and intestinal electricity". With the intensive research on the electrical characteristics of the stomach, the biosensing technology and the electronic technology are widely applied to medical instruments and are rapidly developed. In the prior art, weak gastrointestinal electrical signals with very low frequency on the body surface of a human body can be guided out, interference factors are eliminated, a gastrointestinal electrogram is recorded, and a specific treatment scheme is formulated and generated according to the recorded gastrointestinal electrogram, for example, electrical activity of a gastrointestinal pacing point can be driven by external current stimulation, so that disordered gastrointestinal electricity is promoted to generate a 'following-resonance effect', and accordingly, gastrointestinal functional activity is restored or changed, and the purpose of eliminating or relieving gastrointestinal functional diseases is achieved.
In the prior art, various electronic medical devices for detecting and treating gastrointestinal electrical information appear on the market, and generally, a physiotherapy scheme needs to be formulated by a doctor according to the detected gastrointestinal electrical information for treating a patient; another class of products does not require physician intervention, but only involves a few fixed treatment regimens. The above product has the following disadvantages: 1. physician intervention adds cost to the treatment and the physician experience is limited; 2. several fixed treatment regimens do not meet the therapeutic needs of different gastrointestinal disorders in different patients.
Disclosure of Invention
Technical problem
In view of this, the technical problem to be solved by the present invention is how to generate a targeted physiotherapy plan that can achieve a good physiotherapy effect with reduced intervention of a doctor.
Solution scheme
The invention provides an intelligent gastrointestinal physiotherapy device, which comprises: the acquisition unit is used for acquiring gastrointestinal electrical parameters of a subject before the subject receives the staged physical therapy, wherein the gastrointestinal electrical parameters comprise gastric electrical parameters and/or intestinal electrical parameters; a physiotherapeutic parameter generation unit for generating multiple intermediate values net by weighted summation of multiple groups of weight coefficient sequencespN, N is the number of parameters in the physiotherapy parameters and is based on each intermediate value netpGenerating corresponding physical therapy parameters up(ii) a An electrical stimulation signal generation unit based on the physical therapy parameter u1,…,uNAn electrical stimulation signal is generated.
In a possible implementation, each intermediate value netpCan generate corresponding u based on the same mapping rulep。
In a possible implementation, each intermediate value netpCorresponding physical therapy parameters upThe intervals may be monotonically increasing.
In a possible implementation, each intermediate value netpCorresponding physical therapy parameters upThe relationship between may be one of the following: u. ofp＝f(netp)＝λa·netp+ b, wherein, λaIs a predefined constant greater than zero, b is a predefined constant;wherein λ isbIs a predefined constant greater than zero.
In one possible implementation, the gastrointestinal electrical parameter may include some or all of: main frequency, main power, postprandial power ratio before meal, main frequency instability coefficient; and/or the treatment parameters may include some or all of the following: signal wave frequency, signal wave duty cycle, carrier frequency, carrier amplitude, and carrier waveform shape.
In one possible implementation, the gastrointestinal electrical parameter may also include a frequency of the second harmonic and/or a power of the second harmonic.
In one possible implementation, the apparatus may further include: and the weight coefficient adjusting unit is used for adjusting part or all of the plurality of groups of weight coefficient sequences based on the acquired gastrointestinal electrical parameters for subsequent physical therapy parameter generation under the condition that a preset weight adjusting condition is met.
In one possible implementation, the apparatus may further include: a judging unit, which judges whether to adjust part or all of the multiple groups of weight coefficient sequences based on the times that the physiotherapy effect does not reach the preset expectation in the completed multiple times of stage physiotherapy and the times that the physiotherapy effect reaches the preset expectation; and the weight coefficient adjusting unit adjusts part or all of the plurality of groups of weight coefficient sequences for subsequent physical therapy parameter generation when the judging unit judges that part or all of the plurality of groups of weight coefficient sequences are adjusted.
In a possible implementation manner, in the determining unit, in the case that it is determined that some or all of the plurality of sets of weight coefficient sequences are adjusted, counting of the number of times that the physiotherapy effect does not reach the predetermined expectation and the number of times that the physiotherapy effect reaches the predetermined expectation may be restarted.
In one possible implementation, for each of the phased treatments, if ebef≤γeafterIf the periodic physiotherapy does not meet the preset expectation; if epre＞γeafterIf so, the periodic physiotherapy is considered to reach the preset expectation; wherein, vi_optideal for gastrointestinal electrical parameter numbered iA value; v. ofi_befThe value of the gastrointestinal electrical parameter with the number i is acquired by the acquisition unit before the stage physical therapy; v. ofi_afterThe value of the gastrointestinal electrical parameter with the serial number i is acquired by the acquisition unit after the stage physical therapy; γ is a predefined constant equal to or greater than 1; m is the number of parameters in the gastrointestinal electrical parameters.
In a possible implementation manner, in the determining unit, the determining may include:
initialization w1＝Z,w20, and Z is a preset value;
after each time of the periodic physiotherapy of the multiple periodic physiotherapy, if the physiotherapy effect of the periodic physiotherapy does not reach the predetermined expectation, for w1,w2The following adjustments were made:if the effect of the periodic physiotherapy reaches the predetermined expectation, for w1,w2The following adjustments were made: w is a1＝w1-1,w2＝w2+1；
At w1≥w2In the case of (3), it can be determined that the weight coefficient sequence is not adjusted; if w is1＜w2It may be determined to adjust some or all of the plurality of sets of weighting coefficient sequences.
In one possible implementation manner, in the weight coefficient adjusting unit, the adjusting may include: adjusted based on Wherein,in the last stage of physiotherapyGenerating an intermediate value netpA weighting factor corresponding to the gastrointestinal electrical parameter numbered i;for adjusted, in generating intermediate value netpA weighting factor corresponding to the gastrointestinal electrical parameter numbered i; v. ofi_preIs the value of the gastrointestinal electrical parameter with the number i which is collected before the last periodic physiotherapy is carried out; v. ofi_optThe ideal value of the gastrointestinal electrical parameter numbered i, η is a predefined constant parameter.
In one possible implementation, in the electrostimulation signal generating unit, the physiotherapeutic parameter u is based onp，u1,…,uNGenerating the electrical stimulation signal may include: according to dj＝Rj·Gj·AjGenerating the electrical stimulation signal, wherein j is a serial number of a discrete sample of an electrical stimulation waveform; rjDescribing the electrical stimulation signals generatedWherein f issTo sample the frequency u1Is the frequency of signal wave in physical therapy parameters, u2The duty ratio of a signal wave in the physical therapy parameters; gjAs a function of the carrier frequency and the shape of the carrier waveform of the electrical stimulation signal generated, GjIs determined based on the carrier frequency and the carrier waveform shape in the physical therapy parameters; a. thejAs a function of the amplitude of the electrical stimulation signal generated, AjIs determined based on the carrier amplitude in the therapy parameters.
In one possible implementation, the carrier waveform shape of the electrical stimulation signal may be selected from: sine waves, sawtooth waves, pulse waves, and exponential waves.
Advantageous effects
By collecting the gastrointestinal electrical parameters of the subject and taking the weighted sum of the gastrointestinal electrical parameters as a key intermediate value, the physiotherapeutic parameters are generated according to the key intermediate value to apply targeted physiotherapeutic treatment. The above process basically does not need doctor intervention, can effectively reduce treatment cost, and can generate a targeted geographic treatment scheme. And a large number of verifications prove that the physiotherapy parameters generated by the invention are applied to carry out targeted geographic therapy on patients, so that a good physiotherapy effect can be obtained.
Other features and aspects of the present invention will become apparent from the following detailed description of exemplary embodiments, which proceeds with reference to the accompanying drawings.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate exemplary embodiments, features, and aspects of the invention and, together with the description, serve to explain the principles of the invention.
Fig. 1 illustrates a block diagram of an intelligent gastrointestinal physiotherapy apparatus according to an example of an embodiment of the present invention.
Figure 2 shows a schematic diagram of the process of generating a therapy parameter from a gastrointestinal electrical parameter.
Fig. 3a shows an exemplary mapping rule diagram according to an embodiment of the invention.
Fig. 3b shows a schematic diagram of another exemplary mapping rule according to an embodiment of the invention.
Fig. 4 illustrates a waveform diagram of an electrical stimulation signal according to an example of an embodiment of the present invention.
Fig. 5 is a diagram illustrating an adjustment of the weighting coefficients based on gastrointestinal electrical parameters according to an exemplary application of an embodiment of the present invention.
Detailed Description
Various exemplary embodiments, features and aspects of the present invention will be described in detail below with reference to the accompanying drawings. In the drawings, like reference numbers can indicate functionally identical or similar elements. While the various aspects of the embodiments are presented in drawings, the drawings are not necessarily drawn to scale unless specifically indicated. In the present invention, "·" represents a numerical multiplication unless otherwise specified.
The word "exemplary" is used exclusively herein to mean "serving as an example, embodiment, or illustration. Any embodiment described herein as "exemplary" is not necessarily to be construed as preferred or advantageous over other embodiments.
Furthermore, in the following detailed description, numerous specific details are set forth in order to provide a better understanding of the present invention. It will be understood by those skilled in the art that the present invention may be practiced without some of these specific details. In some instances, methods, procedures, components, and circuits that are well known to those skilled in the art have not been described in detail so as not to obscure the present invention.
Example 1
Fig. 1 illustrates a block diagram of an intelligent gastrointestinal physiotherapy apparatus according to an example of an embodiment of the present invention. As shown in fig. 1, the apparatus mainly includes: the acquisition unit 101 is used for acquiring gastrointestinal electrical parameters of a subject before the subject receives a staged physical therapy, wherein the gastrointestinal electrical parameters comprise a gastric electrical parameter and/or an intestinal electrical parameter; a physical therapy parameter generating unit 102 for performing a weighted summation of the gastrointestinal electrical parameters by using a plurality of sets of weighting coefficient sequences to generate a plurality of corresponding intermediate values netpN, N is the number of parameters in the physiotherapy parameters and is based on each intermediate value netpGenerating corresponding physical therapy parameters up(ii) a An electrical stimulation signal generation unit 103 based on the physical therapy parameter u1,…,uNAn electrical stimulation signal is generated.
In this example, the electrical stimulation signal is generated by acquiring the gastrointestinal electrical parameters of the subject, performing weighted summation on the acquired gastrointestinal electrical parameters by using a plurality of sets of weighting coefficient sequences to generate a plurality of corresponding key intermediate values, and generating corresponding physical therapy parameters based on each key intermediate value, so as to apply targeted physical therapy. The above process basically needs no doctor intervention, can effectively reduce the treatment cost, and is not limited by the experience of doctors. In addition, because the electrical stimulation signals for treatment are automatically generated according to the acquired gastrointestinal electrical parameters, the blindness of the previous treatment is avoided, and the treatment is more targeted. And a large number of verifications prove that the physiotherapy parameters generated by the invention are applied to carry out targeted geographic therapy on patients, so that a good physiotherapy effect can be obtained.
Acquisition unit 101
In this embodiment, before the subject receives the periodic physical therapy, the acquisition unit 101 may acquire the gastrointestinal electrical parameters of the subject and transmit the gastrointestinal electrical parameters to the physical therapy parameter generation unit 102, so as to generate the electrical stimulation signal for physical therapy. Wherein the gastrointestinal electrical parameter may comprise a gastrointestinal electrical parameter and/or a gastrointestinal electrical parameter. In one possible implementation, the physiotherapeutic parameters may be selected according to gastro-intestinal electrical detection criteria, in general, for example, the gastro-intestinal electrical parameters may include some or all of the following: main frequency, main power, postprandial power ratio before meal, main frequency instability coefficient and the like. In another possible implementation, in order to make the generated electrical stimulation signal more accurate, the gastrointestinal electrical parameter may further include the frequency of the second harmonic and/or the power of the second harmonic, and the parameter may reflect the characteristics of the electrical parameter waveform in very detail, so as to make the physical therapy effect better.
The acquisition unit 101 may be any component known to those skilled in the art that can acquire gastrointestinal electrical parameters of a subject, may be a component available in the existing market that can acquire gastrointestinal electrical parameters of a subject, or may be a combination of multiple modules that implement different functions according to actual needs by those skilled in the art, so as to acquire gastrointestinal electrical parameters of a subject. This embodiment is not limited thereto.
Physical therapy parameter generation unit 102
In one possible implementation, physiotherapyThe parameter generating unit 102 may receive the gastrointestinal electrical parameters from the acquiring unit 101, perform weighted summation on the gastrointestinal electrical parameters by using a plurality of sets of weighting coefficient sequences to generate a plurality of corresponding intermediate values, and generate a corresponding therapy parameter based on each intermediate value. For example, the therapy parameter generation unit 102 may receive a plurality of gastrointestinal electrical parameters, e.g., v, from the acquisition unit 1011,...vq,..vMQ is 1.., M is the number of parameters in the gastrointestinal electrical parameters acquired by the acquisition unit 101, v isqThe qth gastrointestinal electrical parameter (gastric electrical parameter or intestinal electrical parameter). For each physical therapy parameter upThere is a sequence of weight coefficients corresponding theretoCan pass throughFirst obtaining a key intermediate value netpThen based on the key intermediate value netpGenerating corresponding physical therapy parameters up. Sequence of weight coefficientsMay be predefined by those skilled in the art based on past experience, wherein each weight value may be a constant value greater than or equal to 0. Figure 2 shows a schematic diagram of the process of generating a therapy parameter from a gastrointestinal electrical parameter. In this example, for each therapy parameter upIn generating its intermediate value netpWhen taking into account all of the acquired gastrointestinal electrical parameters (i.e., theEach of which may not be 0).
In one possible implementation, the therapy parameters may be selected according to the requirements of the therapy method to be used, for example, if a medium frequency therapy method is to be used, the therapy parameters may include some or all of the following: signal wave frequency, signal wave duty cycle, carrier frequency, carrier amplitude, carrier waveform shape, and the like.
In a possible implementation, each intermediate value netpCorresponding u may all be generated based on the same mapping rulep. In this example, since each netpAnd upThe same mapping rule is adopted, so that the complexity of the algorithm is facilitated to be simplified, and the generated physical therapy parameters have better matching degree.
In a possible implementation, each intermediate value netpCorresponding physical therapy parameters upThe intervals may be monotonically increasing. For example, in one example, each intermediate value netpCorresponding physical therapy parameters upThe relation between, i.e. the mapping rule, may be up＝f(netp)＝λanetp+ b, wherein, λaIs a predefined constant greater than zero and b is a predefined constant, as shown in fig. 3 a. In another example, the mapping rule may also beWherein λ isbIs a predefined constant greater than zero, as shown in fig. 3 b. In another example, the mapping rule may also be other rules fitted from empirical results of clinical stages.
The therapy parameter generation unit 102 may be implemented by a general-purpose processor in combination with logic instructions, or may be implemented by dedicated hardware circuitry. The physiotherapeutic parameter generating unit 102 may also be obtained by any suitable technical means by those skilled in the art.
Electrical stimulation signal generation unit 103
In this example, the electrical stimulation signal generation unit 103 may be based on the physical therapy parameter u from the physical therapy parameter generation unit 1021,…,uNAn electrical stimulation signal is generated. In one possible implementation, d may be based onj＝Rj·Gj·AjGenerating the electrical stimulation signal, wherein j is a serial number of a discrete sample of an electrical stimulation waveform;wherein f issTo sample the frequency u1The frequency of the signal wave in the physical therapy parameters; u. of2The duty ratio of a signal wave in the physical therapy parameters; mod represents a modulo operation; [ x ] of]Expressing a rounding operation, namely taking the maximum integer less than or equal to x; gjAs a function of the carrier frequency and the shape of the carrier waveform of the electrical stimulation signal generated, GjIs determined based on the carrier frequency and the carrier waveform shape in the physical therapy parameters; a. thejAs a function of the amplitude of the electrical stimulation signal generated, AjIs determined based on the carrier amplitude in the therapy parameters.
In this example, the carrier waveform shape of the electrical stimulation signal may include some or all of: sine waves, sawtooth waves, pulse waves, and exponential waves.
In a specific application example, taking preparation for adopting the medium-frequency physiotherapy method as an example, in general, f can be set to ensure higher accuracy of obtaining an electrical stimulation signals≥10u1。
Fig. 4 is a screen display image showing a waveform diagram of a certain exemplary electrical stimulation signal including a sine wave, a sawtooth wave, a pulse wave, and an exponential wave. It is understood that the partial characters in fig. 4 cannot be clearly displayed due to the limitation of resolution, but the unclear characters do not affect the technical solution and the technical effect of the present invention understood by those skilled in the art.
The electrical stimulation signal generation unit 103 may be implemented by a general-purpose processor in combination with logic instructions, or may be implemented by dedicated hardware circuitry. The physical therapy parameter generating unit 103 can also be obtained by any suitable technical means by those skilled in the art.
In a possible implementation manner, the apparatus further includes a weight coefficient adjusting unit, and in a case that a preset weight adjusting condition is satisfied, some or all of the plurality of sets of weight coefficient sequences may be adjusted for subsequent therapy parameter generation based on the acquired gastrointestinal electrical parameter. Those skilled in the art can set appropriate weight adjustment conditions as needed, and set which weight coefficients in the multiple sets of weight coefficient sequences are adjusted as needed, for example, all weight coefficients in all weight coefficient sequences may be adjusted, all weight coefficients in partial weight coefficient sequences may be adjusted, partial weight coefficients in each weight coefficient sequence may be adjusted, or partial weight coefficients in partial weight coefficient sequences may be adjusted. By utilizing the weight coefficient adjusting unit, the weight coefficient sequence can be continuously optimized to be close to the optimal value, so that the optimal physiotherapy electric signal for each patient can be generated conveniently, and the optimal physiotherapy effect can be obtained. The optimal value is difficult to determine when the instrument leaves a factory, and intelligent learning and evolution of the gastrointestinal physiotherapy device can be realized through the weight coefficient adjusting unit.
In a possible implementation, the apparatus may further include a judging unit and a weight coefficient adjusting unit. The judging unit can judge whether to adjust part or all of the multiple groups of weight coefficient sequences based on the times that the physiotherapy effect does not reach the preset expectation in the multiple-stage physiotherapy and the times that the physiotherapy effect reaches the preset expectation, so that the improper weight coefficients can be adjusted in time, the low efficiency caused by too frequent adjustment can be avoided, and the wrong adjustment of the weight coefficients caused by accidental wrong measurement of a certain time can be avoided. In a case where the determination unit determines to adjust part or all of the plurality of sets of weight coefficient sequences, the weight coefficient adjustment unit may adjust part or all of the plurality of sets of weight coefficient sequences. The weight coefficient adjustment can be performed by any means deemed suitable by the person skilled in the art.
In one example, in the determination unit, in a case where it is determined that some or all of the plurality of sets of weight coefficient sequences are adjusted, counting of the number of times the physical therapy effect does not reach the predetermined expectation and the number of times the physical therapy effect reaches the predetermined expectation may be restarted.
In one example, for each of the phased treatments, if ebef≤γeafterIf the periodic physiotherapy does not meet the preset expectation, the physiotherapy effect is not good; if epre＞γeafterThen, the periodic physiotherapy can be considered to reach the preset expectation, and the physiotherapy effect is better. Wherein, vi_optmay be an ideal value for the gastrointestinal electrical parameter numbered i; v. ofi_befThe value of the gastrointestinal electrical parameter with the number i collected by the collecting unit before the stage physical therapy; v. ofi_afterThe value of the gastrointestinal electrical parameter with the number i collected by the collecting unit after the periodic physiotherapy can be used as the value; γ may be a predefined constant equal to or greater than 1; m may be the number of parameters in the gastrointestinal electrical parameter.
For example, in the determination unit, w may be initialized1＝Z,w20, and Z is a preset value; after each time of periodic physiotherapy, if the physiotherapy effect of the periodic physiotherapy is judged not to reach the preset expectation, the treatment can be performed on the w1,w2The following adjustments were made:if the physiotherapy effect of the stage physiotherapy reaches the preset expectation, the treatment can be performed on the w1,w2The following adjustments were made: w is a1＝w1-1,w2＝w2+1. At w1≥w2Under the condition of (1), the physical therapy time is considered to be short or the physical therapy effect is considered to be good, and the weight coefficient sequence can be judged not to be adjusted temporarily; at w1＜w2In the case of (1), the physiotherapy effect for the period of time is considered to be unsatisfactory, and it can be determined that a plurality of sets of weighting coefficients are requiredSome or all of the sequences are adjusted. At w1＜w2In the case of (3), w may be initialized again1＝Z,w2When it is 0, the next round of statistics is started.
In the above-described embodiments, the weight adjustment unit may perform the adjustment using the following gradient descent learning process. Can be adjusted based on the following formula Wherein,for generating an intermediate value net in the last-stage physiotherapypA weighting factor corresponding to the gastrointestinal electrical parameter numbered i;for adjusted, in generating intermediate value netpThe weight coefficient corresponding to the gastrointestinal electrical parameter with number i can be used in the subsequent physiotherapySubstitutionTo generate a netpFurther generate corresponding physical therapy parameters up；vi_preIs the value of the gastrointestinal electrical parameter with the number i which is collected before the last periodic physiotherapy is carried out; v. ofi_optI, i.e., the gastrointestinal electrical parameter of the subject in a healthy condition, and η, a predefined constant parameter, which may be referred to as a learning rate, u, i.e., a physiotherapeutic parameterp＝f(netp) Step size along gradient direction;for derivation operations, e.g. inIn the case of (a) in (b),fig. 5 is a diagram illustrating an adjustment of the weighting coefficients based on gastrointestinal electrical parameters according to an exemplary application of an embodiment of the present invention. In this example, when the adjustment is confirmed, for example, a preset weight adjustment condition is satisfied or it is judged by the judgment unit that the adjustment is necessary, the weight coefficient adjustment unit may adjust all the weight parameters using the above-described gradient descent learning process.
The judging unit and/or the weight coefficient adjusting unit are/is realized by a general processor combined with logic instructions, and can also be realized by a special hardware circuit. The determining unit and/or the weight coefficient adjusting unit may be implemented by any other suitable technical means by those skilled in the art.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.
Claims (14)
1. An intelligent gastrointestinal physiotherapy device, characterized in that the device comprises:
the acquisition unit is used for acquiring gastrointestinal electrical parameters of a subject before the subject receives the staged physical therapy, wherein the gastrointestinal electrical parameters comprise gastric electrical parameters and/or intestinal electrical parameters;
a physiotherapeutic parameter generation unit for generating multiple intermediate values net by weighted summation of multiple groups of weight coefficient sequencespN, N is the number of parameters in the physiotherapy parameters and is based on each intermediate value netpGenerating corresponding physical therapy parametersup；
An electrical stimulation signal generation unit based on the physical therapy parameter u1,…,uNAn electrical stimulation signal is generated.
2. Device according to claim 1, characterised in that each intermediate value netpAll generate corresponding u based on the same mapping rulep。
3. Device according to claim 1, characterised in that each intermediate value netpCorresponding physical therapy parameters upThe interval is monotonically increasing.
4. Device according to any one of claims 3, characterised in that each intermediate value netpCorresponding physical therapy parameters upThe relationship between is one of the following:
up＝f(netp)＝λa·netp+ b, wherein, λaIs a predefined constant greater than zero, b is a predefined constant;
wherein λ isbIs a predefined constant greater than zero.
5. The apparatus of claim 1,
the gastrointestinal electrical parameters include some or all of the following: main frequency, main power, postprandial power ratio before meal, main frequency instability coefficient;
and/or the physical therapy parameters include some or all of the following: signal wave frequency, signal wave duty cycle, carrier frequency, carrier amplitude, and carrier waveform shape.
6. The device of claim 5, wherein the gastrointestinal electrical parameter further comprises a frequency of a second harmonic and/or a power of the second harmonic.
7. The apparatus of claim 1, further comprising:
and the weight coefficient adjusting unit is used for adjusting part or all of the plurality of groups of weight coefficient sequences based on the acquired gastrointestinal electrical parameters for subsequent physical therapy parameter generation under the condition that a preset weight adjusting condition is met.
8. The apparatus of claim 1, further comprising:
the judging unit judges whether to adjust part or all of the multiple groups of weight coefficient sequences based on the times that the physiotherapy effect does not reach the preset expectation in the completed multiple times of stage physiotherapy and the times that the physiotherapy effect reaches the preset expectation;
and the weight coefficient adjusting unit is used for adjusting part or all of the plurality of groups of weight coefficient sequences for subsequent generation of physical therapy parameters under the condition that the judging unit judges that part or all of the plurality of groups of weight coefficient sequences are adjusted.
9. The apparatus according to claim 8, wherein in the judging unit, in the case where it is judged that some or all of the plurality of sets of the weight coefficient sequences are adjusted, counting of the number of times the physiotherapy effect does not reach the predetermined expectation and the number of times the physiotherapy effect reaches the predetermined expectation is restarted.
10. The apparatus according to claim 8, wherein, in the judging unit, for each of the periodical physiotherapy,
if ebef≤γeafterIf the periodic physiotherapy does not meet the preset expectation;
if epre＞γeafterThen the stage physical therapy is considered to reach the predetermined expectation；
Wherein,vi_optis an ideal value of the gastrointestinal electrical parameter with the number i; v. ofi_befThe value of the gastrointestinal electrical parameter with the number i is acquired by the acquisition unit before the stage physical therapy; v. ofi_afterThe value of the gastrointestinal electrical parameter with the serial number i is acquired by the acquisition unit after the stage physical therapy; γ is a predefined constant equal to or greater than 1; m is the number of parameters in the gastrointestinal electrical parameters.
11. The apparatus according to claim 8, wherein in the judging unit, the judging includes:
initialization w1＝Z,w20, and Z is a preset value;
after each time of the periodic physiotherapy of the multiple periodic physiotherapy, if the physiotherapy effect of the periodic physiotherapy does not reach the predetermined expectation, for w1,w2The following adjustments were made:if the effect of the periodic physiotherapy reaches the predetermined expectation, for w1,w2The following adjustments were made: w is a1＝w1-1,w2＝w2+1；
At w1≥w2Under the condition of (1), judging not to adjust the weight coefficient sequence; if w is1＜w2And judging to adjust part or all of the multiple groups of weight coefficient sequences.
12. The apparatus according to any one of claims 7-11, wherein in the weight coefficient adjusting unit, the adjusting comprises:
adjusted based on
Wherein,for generating an intermediate value net in the last-stage physiotherapypA weighting factor corresponding to the gastrointestinal electrical parameter numbered i;for adjusted, in generating intermediate value netpTime corresponds to the numberA weight coefficient for the gastrointestinal electrical parameter of i; v. ofi_preIs the value of the gastrointestinal electrical parameter with the number i which is collected before the last periodic physiotherapy is carried out; v. ofi_optThe ideal value of the gastrointestinal electrical parameter numbered i, η is a predefined constant parameter.
13. The apparatus according to claim 1, wherein the electrical stimulation signal generating unit generates the electrical stimulation signal based on the physical therapy parameter up，u1,…,uNGenerating the electrical stimulation signal includes:
according to dj＝Rj·Gj·AjGenerating the electrical stimulation signal, wherein j is a serial number of a discrete sample of an electrical stimulation waveform;wherein f issTo sample the frequency u1Is the frequency of signal wave in physical therapy parameters, u2The duty ratio of a signal wave in the physical therapy parameters; gjAs a function of the carrier frequency and the shape of the carrier waveform of the electrical stimulation signal generated, GjIs determined based on the carrier frequency and the carrier waveform shape in the physical therapy parameters; a. thejAs a function of the amplitude of the electrical stimulation signal generated, AjIs determined based on the carrier amplitude in the therapy parameters.
14. The apparatus of claim 13, wherein the carrier waveform shape of an electrical stimulation signal comprises some or all of:
sine waves, sawtooth waves, pulse waves, and exponential waves.
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