[go: up one dir, main page]

CN106102596A - 可植入医疗装置约束和部署设备 - Google Patents

可植入医疗装置约束和部署设备 Download PDF

Info

Publication number
CN106102596A
CN106102596A CN201580011920.6A CN201580011920A CN106102596A CN 106102596 A CN106102596 A CN 106102596A CN 201580011920 A CN201580011920 A CN 201580011920A CN 106102596 A CN106102596 A CN 106102596A
Authority
CN
China
Prior art keywords
sheath
deployment
implantable device
medical treatment
implantable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201580011920.6A
Other languages
English (en)
Other versions
CN106102596B (zh
Inventor
C·W·欧文
J·D·西尔弗曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WL Gore and Associates Inc
Original Assignee
WL Gore and Associates Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WL Gore and Associates Inc filed Critical WL Gore and Associates Inc
Priority to CN201910476286.3A priority Critical patent/CN110051399B/zh
Publication of CN106102596A publication Critical patent/CN106102596A/zh
Application granted granted Critical
Publication of CN106102596B publication Critical patent/CN106102596B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/856—Single tubular stent with a side portal passage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12122—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder within the heart
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01—Filters implantable into blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01—Filters implantable into blood vessels
    • A61F2/011—Instruments for their placement or removal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/9522—Means for mounting a stent or stent-graft onto or into a placement instrument
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/9522—Means for mounting a stent or stent-graft onto or into a placement instrument
    • A61F2/9525—Means for mounting a stent or stent-graft onto or into a placement instrument using a funnel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/962—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/962—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
    • A61F2/966—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12168—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
    • A61B17/12177—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/00579—Barbed implements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/00592—Elastic or resilient implements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/00597—Implements comprising a membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/00601—Implements entirely comprised between the two sides of the opening
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/00623—Introducing or retrieving devices therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205—Introduction devices
    • A61B2017/12054—Details concerning the detachment of the occluding device from the introduction device
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/9517—Instruments specially adapted for placement or removal of stents or stent-grafts handle assemblies therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/954—Instruments specially adapted for placement or removal of stents or stent-grafts for placing stents or stent-grafts in a bifurcation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01—Filters implantable into blood vessels
    • A61F2002/016—Filters implantable into blood vessels made from wire-like elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2002/9505—Instruments specially adapted for placement or removal of stents or stent-grafts having retaining means other than an outer sleeve, e.g. male-female connector between stent and instrument
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2002/9505—Instruments specially adapted for placement or removal of stents or stent-grafts having retaining means other than an outer sleeve, e.g. male-female connector between stent and instrument
    • A61F2002/9511—Instruments specially adapted for placement or removal of stents or stent-grafts having retaining means other than an outer sleeve, e.g. male-female connector between stent and instrument the retaining means being filaments or wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining
    • Y10T29/49863—Assembling or joining with prestressing of part
    • Y10T29/4987—Elastic joining of parts
    • Y10T29/49872—Confining elastic part in socket

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Prostheses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surgical Instruments (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

公开了一种可植入医疗装置部署系统，该系统采用护套元件(26)和约束构件(32)以在体内递送期间保护可植入医疗装置，同时提供简单、精确和可靠的装置部署。该递送系统构造成使得加载和部署力不直接与装置直径、长度或设计相关，因此允许跨越各种递送装置构造和产品线的更通用递送系统。该部署系统可提供多个优点，包括对涂有药物的可植入装置的更好保护。

Description

可植入医疗装置约束和部署设备
发明背景
技术领域
本发明涉及用于递送和部署可移植医疗装置的设备和方法。
背景技术
随着复杂的可植入医疗装置和更先进的治疗设备，以及诸如支架、支架-移植物、囊体、过滤器、封堵器等通过最小侵入手术递送和部署的特定医疗装置和处理的逐渐发展，对于发现有效地约束、递送和/或部署这些装置和治疗设备的改进装置和方法越来越关注。
用于递送和部署这些装置的先前装置和方法的示例包括使用外翻套管来约束可植入装置并然后以受控方式就地展开该装置，诸如Austin的美国专利7,285,130、Koss等人的美国申请2008-0281398和Cully等人的PCT申请WO13025470中描述的装置。使用这些文献中所描述的外翻套筒具有多个优点，但对于可有效地安装在多个这些套筒内并从其展开的装置的长度、几何形状、拉伸强度和其它特性都有限制。此外，现有外翻套管部署设备已经受到在部署之前对可植入装置的充分约束与可植入装置在体内所需位置精确和方便部署之间平衡的挑战。
在Armstrong等人的美国专利6,315,792中描述了技术和商业上成功的另一现有约束和递送设备。该设备采用在部署之前约束可植入装置的针织纤维覆盖件，然后移除该覆盖件以允许装置部署在体内所需位置。尽管该设备工作良好，但对于可有效约束和部署的可植入装置的尺寸和类型还有各种限制。该约束和其它纤维约束的一个问题是该纤维覆盖物可能不会从某些装置几何形状或特征平滑安装和/或部署(例如，纤维可能挂住倒钩或可植入装置上的其它特征)。
甚至最近更关注提供覆盖有药物或其它生物活性剂的可植入装置和治疗设备进一步增加了有效约束和递送这些装置的挑战。通过漏斗将涂有药物的装置拉入约束设备的动作有生物活性剂可能在装载和安装过程期间移除和移位的严重风险，这会危及刚部署好的装置的有效性。类似地，部署期间约束构件和可植入装置之间的相互作用还产生生物活性剂可能未保持适当施加到刚完全部署好的装置的风险。
发明内容
本发明提供一种可缩放递送系统，其在体内递送期间保护医疗装置、同时提供简单、精确和可靠的装置部署(deployment,展开)。该递送系统构造成使得加载和部署力(展开力)不直接与装置直径、长度或设计相关，因此提供跨越各种递送的装置构造和产品线的更有用递送系统。
本发明的递送系统的优点有：更可预测的部署力，这种力便于更平稳和更可预测的装置递送(例如通过减小可植入装置与约束件之间的不利相互作用，钩住和导管移位的风险更小)；能够部署(展开)具有不规则特征的装置(例如扇形孔、倒钩、锚固件、顶点和可能否则与部署设备的平稳操作干涉的其它特征)；能够形成具有更小装置递送轮廓的装置；能够将各递送线包含在护套内从而减小或消除部署(展开)期间线的“弓弦现象”；以及能够在制造和递送期间保护可植入装置免受剪切力，这对于保护施加到装置的各种涂层(例如药物或其它生物活性材料)免受损坏或过早释放是尤其有用的。
本发明的另一优点在于其赋予所递送装置以最小应力。在本发明中，递送装置在加载之前被封装并保持封装直到部署(展开)为止。对于药物递送装置，这减少药物损失和颗粒化。这还可能消除装置安装期间装置与工具之间的接触，并在装载和部署(展开)期间将装置与表面剪切隔离开。本发明还可消除装载期间装置的张紧，从而允许更小的可植入装置质量和更小的轮廓。
在本发明的一实施例中，提供一种用于可植入医疗装置的部署系统，包括：可膨胀医疗装置，该可膨胀医疗装置具有较大的部署(展开)直径和用于递送的较小的紧实直径；护套，该护套围绕较小紧实的医疗装置，护套外翻回到自身上，其中护套的外部围绕护套的内部；以及细丝状约束构件，该细丝状约束构件位于护套的内部与外部之间，其中通过对护套和细丝状约束构件同时施加致动力而将医疗装置部署(展开)成较大直径。
在本发明的另一实施例中，提供一种用于将可植入装置加载在部署系统上的方法，包括：提供可植入装置；将可植入装置防止在护套元件内，护套元件包括延伸超过可植入装置的段；提供漏斗和约束元件；在护套的该段上施加拉伸力以将护套元件和可植入装置拉过漏斗，从而将可植入装置紧实(compact，压实，压缩)在护套元件内并进入约束构件，从而将可植入装置约束在紧实状态下；其中护套元件和约束元件构造成在使用时被移除，以部署(展开)可植入装置。
在涉及装置部署的本发明另一实施例中，提供一种医疗装置部署系统，包括：第一护套和第二护套，其中第一和第二护套中的每个通过对连接到第一和第二护套中的每个护套的拉伸构件施加拉伸力而不成比例地被致动，其中在通过施加单个输入力部署(展开)时，输入力可变地分布在各拉伸构件之间。
在本发明的另一实施例中，提供一种医疗装置部署系统，包括：通过转动行星滚动元件而啮合的两个或多个滑轮，其中滑轮中的每个构造成积聚部署线(deployment wire，展开线)，其中部署线致动医疗装置的部署(展开)。
附图说明
包含附图以提供对本发明的进一步理解，并且附图包含在本说明书中并构成本说明书的一部分，附图示出了本发明的实施例，并且与说明一起用于阐释本发明的原理。
图1是约束在本发明的递送和部署设备内的可植入装置的侧剖视图。
图2是在约束于本发明的递送和部署设备内之前可植入装置的侧视图。
图3是围绕图2所示可植入装置的本发明的牵引管护套元件的侧视图。
图4是图3所示护套元件和可植入装置组合通过漏斗被拉入约束构件内的部分剖切的侧视图。
图5是图3所示护套元件和可植入装置组合被径向压缩并然后被拉入约束构件的部分剖切侧视图。
图6示出是在安装在递送导管上之前图4或图5所示过程中形成的护套元件、可植入装置和约束构件组合的侧视图。
图7是示出安装在递送导管上并具有形成为可植入装置部署期间实现护套元件和约束构件的移除的牵拉线的、图6所示护套元件、可植入装置和约束构件组合的部分剖切侧视图。
图8是图7所示可植入装置和递送设备的部分剖切侧视图，可植入装置示出为部分部署。
图9至图12是可用于实现本发明可采用的同时移除多个牵拉线的各种设备的示意图。
图13是可用于实现本发明可采用的同时移除多个牵拉线的差动齿轮的部分剖切俯视图。
图14是可用于实现本发明可采用的同时移除多个牵拉线的差动齿轮的另一实施例的剖视图。
图15是图3所示护套元件和可植入装置组合被拉入传送漏斗的部分剖切侧视图，其中将护套元件的一部分外翻到传送漏斗上。
图16是第二护套元件外翻到传送管上的侧剖视图。
图17是图15所示可植入装置、护套元件和传送漏斗组合和图16所示第二护套元件和传送管组合布置在彼此邻靠定向下的部分剖切侧视图，且示出可植入装置从传送漏斗部分传送到传送管。
图18是图17所示传送过程之后安装在第二护套内的可植入装置的部分剖切侧视图。
具体实施方式
本发明提供约束、递送和/或部署医疗装置的改进设备。本发明可结合可临时或永久部署在患者体内的各种装置使用，包括但不限于支架、支架-移植物、囊体、过滤器、捕集器、封堵器、用于递送药物或其它治疗物质或治疗的装置等。这样，本发明的术语“医疗装置”和“可植入装置”用于宽泛地诠释为涵盖临时或永久放入体内的任何装置。
本发明的设备可用于递送自膨胀装置、通过囊体或其它装置可膨胀的装置、自膨胀/可膨胀混合装置、以及不用于就位时改变尺寸的装置。
下文借助于图示描述本发明的各具体实施例。本领域的技术人员应理解，本发明人并不意图将本发明的范围限于这些特定实施例。
图1示出本发明的安装在导管22上并约束在部署设备24中的可植入装置20，在该情况下是支架或支架-移植物。部署设备24包括具有外层28和内层30的外翻牵引管护套元件26。约束构件32包含在护套元件26的外层28和内层30内。部署设备(展开设备)24包括第一部署线34和第二部署线36，第一部署线34操作地联接成致动护套26，第二部署线36操作地联接成致动约束构件32。
如下文更详细解释的，护套元件26由适于围绕和保护可植入装置的薄柔性材料构成。柔性材料应当具有足够的纵向拉伸强度，从而其可用作牵引管以在制造过程期间有助于将可植入装置20完全拉过紧实设备(压实设备)并进入约束构件32。较佳地，柔性材料应当还具有足够的覆盖和结构完整性，以保护可植入装置上的任何生物活性涂层或其它表面治疗，直到装置最终部署(展开)在体内。可能更理想的是，柔性护套由可辅助下述制造过程的润滑材料构成。
并不要求护套元件26来提供对可植入装置20的任何显著约束，因为该功能(如果需要)可主要由约束构件32来提供。这样，护套元件26可由非常薄而柔性的材料构成，其呈现一定程度的径向顺应性。实际上，可能理想的是护套元件26在纵向拉伸力下经受颈缩，从而辅助制造期间的紧实过程。
护套元件26的柔性材料可由各种不同材料制成，包括但不限于：连续的材料管或材料片；纺织、针织或其它织物材料；诸如毛毡的非织造材料；或两种或多种不同材料的复合材料。用作护套26的合适材料包括材料管或材料片，可包括但不限于：聚四氟乙烯(PTFE)、膨胀型PTFE、聚酯、聚乙烯、尼龙、人造丝、聚酰亚胺、聚酰胺、聚丙烯和/或聚氨酯。
护套元件26可由径向可扩张材料制成和/或其可构造成各种构造。例如，材料可以是径向可扩张的、或径向颈缩的、和/或具有宽范围的强度或其它特性。此外，可能有益的是构造呈打褶护套或螺旋打褶护套形式的护套元件，从而辅助装置的径向顺应或释放。
如图1所示，在本发明的一实施例中，护套元件26由在其尾端处(在图1所示点37处)分裂的连续管构成，从而由与护套26相同材料形成第一部署线34。部署线(展开线)34可例如通过螺旋缠绕、加热或以其他方式操纵分裂管变为带螺纹的结构而形成。此外，诸如聚酰胺、聚酰亚胺、聚四氟乙烯(PTFE)、膨胀型聚四氟乙烯(ePTFE)、聚酯或类似材料制成的线可以单独使用或附加到分裂管使用，以提供更坚固的部署线构造。
对于支架或支架-移植物装置的部署，合适的护套元件26可包括厚度约0.0015至0.15mm、纵向拉伸强度约0.5至10kgf(公斤力)的膨胀型PTFE的管状护套。护套应具有足够的韧性，以承受可能由约束装置施加的任何应变(例如来自支架顶点、翅片、锚固件等的力)。如下文解释的，对于某些应用，可能理想的是当对护套施加纵向拉伸时，护套能够颈缩到中间直径。护套可由任何合适的基体材料制成，包括但不限于管、片和/或纤维(例如材料的编织或辫织物)。
如已经指出的，约束构件32用于为可植入装置20提供有效约束。这样，约束构件32应由会抵抗由可植入装置20递送的任何膨胀力的相对非顺应性材料制成。约束构件32可由各种不同材料制成，包括但不限于：连续的材料管或材料片；纺织、针织或其它织物材料；诸如毛毡的非织造材料；或两种或多种不同材料的复合材料。此外，可能有益的是构造呈打褶护套或螺旋状打褶护套形式的约束构件32，诸如Irwin等人的美国专利8,845,712中公开的，从而辅助装置的径向顺应或释放。用作约束构件32的合适材料包括材料管、材料片或材料纤维，可包括但不限于：聚四氟乙烯(PTFE)、膨胀型PTFE、聚酯、聚乙烯、尼龙、人造丝、聚酰亚胺、聚酰胺、聚丙烯和/或聚氨酯。
约束构件32可有效地由细丝状材料制成，诸如Armstrong等人的美国专利6,315,792(“Armstrong等人专利”)中描述的，其全文以参见的方式纳入本文。该专利中描述的针织约束构件提供非常有效的装置约束，但在部署(展开)期间易于从可植入装置散开(松开)。如已经指出的，Armstrong等人专利的约束已经证实在可植入装置递送和部署(展开)中是非常精确且有效的。但是，通过将Armstrong等人专利的约束构件32与外翻护套元件26组合，已经证实有显著优点。已经确定，如果Armstrong等人专利中描述的细丝状约束构件单独使用，则各纤维会钩在某些可植入装置结构的各特征上(例如某些形式的锚固件、倒钩、支架顶点等)，这会造成制造期间约束构件的安装困难和/或部署(展开)期间约束构件的释放困难。通过将Armstrong等人专利的细丝状约束构件构造夹在外翻的护套元件26内，护套元件26用于覆盖和隔离可植入装置20上的任何有问题的特征，使得约束构件32可在制造期间容易地安装在可植入装置20上并然后在部署(展开)期间容易地从可植入装置20移除。该优点大大增强了现在能使用Armstrong等人专利的设备成功部署的各种可植入装置。
第二部署线36可包括与约束构件26相同的材料，诸如当根据Armstrong等人专利的某些实施例形成约束构件26时。或者，诸如聚酰胺、聚酰亚胺、聚四氟乙烯、膨胀型聚四氟乙烯、聚酯或类似材料制成的其它材料可以单独使用或附加到部署线36以提供更坚固的构造。
图2至图8示出用于构造本发明的部署设备24的过程。图2示出在安装到本发明的部署设备24内之前诸如支架或支架-移植物的可植入装置20。在图3中，可植入装置20放置在护套元件26内。
在图4中，图3所示的护套元件26和可植入装置20组合通过漏斗38被拉入约束构件32内。如已经指出的，护套元件26正用作牵引管，以提供光滑和均匀的表面以有助于方便可植入装置20通过漏斗38进入约束构件32。在这方面，可施加到可植入装置20的任何涂层因此受保护而免于漏斗38和约束构件32磨损。此外，无论在通过漏斗38缩拉的过程期间护套元件26经受何种程度的任何颈缩，该颈缩力进一步辅助可植入装置20紧实。
应理解，护套元件26还将可植入装置20与将装置20拉动穿过漏斗38并进入约束构件32所需的力隔离开。在更常规的紧实过程中，栓系线通常被施加到可植入装置20的一端，以拉动可植入装置通过漏斗进入约束构件内。这样，可植入装置必须由允许其承受将其紧实到其递送尺寸所必须的相当大的纵向力的材料和方式构造(即，如果可植入装置不足够坚固，则其会在紧实过程期间在栓系线的力下受损)。对于更长的可植入装置构造和当采取更大的紧实比时，紧实力变得显著更大。通过使用本发明的护套元件来沿可植入装置的整个长度施加牵引力，能够有效地紧实可植入装置，该可植入装置否则会太脆弱以至于不能经受通过常规牵引线的紧实和/或以至于不能施加比先前可能大得多的紧实力(且因此实现大得多的紧实比)。在这方面，护套元件在紧实和装载过程中为可植入装置提供增大的轴向长度。
图5中示出替代紧实过程。在该实施例中，图3所示护套元件26和可植入装置20组合通过诸如径向挤压装置的压缩设备40来进行紧实。在该实施例中，护套元件26便于紧实的可植入装置更容易地拉出压缩设备并进入约束构件32，具有先前指出的所有优点。
无论是通过图4或图5所示的过程还是通过如图6所示的任何其它合适的装置紧实，一旦可植入装置20被紧实到约束构件32内，都有从紧实装置20的两侧延伸的额外的护套元件26。如图7所示，约束装置20然后可安装在递送导管22上，且额外的护套元件26可然后向外翻回到约束构件32上，以将约束构件32夹在护套元件26的内层30与外层28内。部署线34然后可附连到护套元件26或从护套元件26形成。同样，部署线36然后可附连到约束构件32或从约束构件32形成(例如，如果约束构件32由针织材料构造而成，诸如Armstrong等人专利描述的，则部署线36可包括由散开的约束构件32形成的线绳)。
应理解，对于某些应用，护套元件26也可用作单层。采用单层护套元件的优点是有机会提供减小的递送轮廓和减小的部署线长度。
一旦以本文所述方式构造，则可植入装置20和部署设备24可以以常规方式递送至患者体内所需处理部位。但是，应当理解，将可植入装置20封装在护套元件26内可在递送过程期间提供了对可植入装置20的附加保护。如已经指出的，当可植入装置20设有药物或其它生物活性涂层时，理想的是涂层在达到预期部署部位之前不会暴露。在某些约束结构、诸如开口网或开口细丝状编织物等的情况下，药物涂层将必然在到达预期部署部位之前很久就暴露于血液和组织，这会导致涂层从装置的可能磨损以及生物活性材料在体内不希望位置的不期望的释放。但是，通过使用本发明的护套元件26，可确保生物活性涂层免受损坏或过早释放，无论约束装置的结构可能如何打开。
一旦将约束装置20适当地定位在体内，则装置20可通过致动两个部署线34和36而释放，约束构件32和护套元件26中的每个在致动时被拉离装置。图8中示出该过程，示出可植入装置20开始从部署设备24部署。
尽管在提供既包括护套元件又包括约束构件的部署设备时有多个显著优点，但已经确定当试图从受约束可植入装置同时去除两个覆盖件时是一个挑战。因为护套元件26和约束构件32由不同材料构成且包括不同形式，它们不太会以相同的速率或相同的方式收缩。此外，根据构造，各部署线可能并非以线性速率致动，因此需要对每根线的致动速率的一定程度调节。这给临床医生提出了试图同时但以不同速率致动两根部署线34和36的不希望的挑战。
本发明人已经确定该挑战可通过采用各种不同机构中的一种来完全解决，各种不同机构允许临床医生对部署设备24施加单个部署力，同时不同机构自动调节每根部署线34和36的致动速率。
图9至图12是可用于实现本发明可采用的同时移除多个牵拉线的各种设备。图9示出两根部署线34各36分别在其终端42和44处附连在一起的差动结构的最简单形式，采用滑轮46使得立即适应每根部署线34、36上变化的缩回速率。临床医生仅对滑轮和护套元件施加单个部署力48，且约束构件将以相同的速率缩回，同时两者之间的任何速率差被滑轮46校正。
图10示出差动结构的另一种形式，由此任何撤回速率差都是预先计算的且使用不同的固定比的滑轮50、52来以其预定速率撤回每根部署线34、36。
图11示出差动结构的又一种形式，由此弹簧或其它无源位移机构54与部署线34关联，部署线34确定为在部署(展开)期间需要最松散(即需要较慢撤回的部署线)。这样，临床医生能以均匀速率拉动两根线，但各线将以其适当的差别速率有效撤回。
图12示出差动机构的又一形式，由此采用离合驱动器56，以使得被驱动的滑轮58以设定的速率收回部署线36之一，且被驱动的滑轮58与第二滑轮62之间的摩擦界面60提供离合机构，使得部署线34将以较慢的速率积聚。
图13总示出更复杂的差动机构。在该实施例中，设置两个滑轮64、66，每个滑轮分别与部署线34、36关联。滑轮锥齿轮68a、68b和行星锥齿轮70a、70b安装在两个滑轮64、66之间，从而允许每个滑轮64、66的不同致动速率。临床医生致动的拇指轮72设置成通过一端固定有拇指轮的中心杆致动行星齿轮，且类似于图12所示的离合机构，行星齿轮70a、70b用于适应两个滑轮64、66之间的不同致动速率。各锥齿轮可选择成以适当的速率致动每个滑轮。例如，可建立滑轮64和66的转动量总和为例如拇指轮72的输入转动量的2倍。
图14中示出类似的差动机构。在该实施例中，滑轮74和76分别与每个部署线(未示出)关联且分别附连到环形齿轮78、80。行星齿轮82、84分别设有与行星齿轮直接啮合的由临床医生致动的拇指轮86。
应理解，本文所述的各种差动机构仅是说明性的且在本发明的范围内可采用任何这些或其它机构。其它各种改进和改良也在本发明的范围内，包括马达或其它驱动机构可代替例如在图13和14的实施例中的拇指轮。
对于某些应用，可能有益的是在可植入装置的最终紧实和安装以进行递送之前将可植入装置传送到中间紧实直径。例如，通过在多个步骤中紧实可植入装置，可使用更薄且不那么牢固的护套可用于最终的装置紧实和递送，这可能允许期望的更小的装置递送尺寸。一种实现方法是用图15至18所示的附加处理步骤更改以上图2至6所示的安装程序。
在图15中，图3所示的护套元件26和可植入装置20组合被拉入传送漏斗88，护套26的一段90外翻到传送漏斗88上(外翻到传送漏斗的外面)。可植入装置20在传送漏斗88内的紧实可通过对该段90施加拉伸92从而将护套26和装置20拉入漏斗88来实现。一旦可植入装置20定位在传送漏斗80的末端94处，则装置准备传送。
图16示出外翻到传送管98外(上)的第二护套元件96。第二护套元件96构造成直径比护套元件26的直径小。传送管98由基本上非顺应性材料构成，诸如金属或塑料海波管。传送管98的直径大约等于传送漏斗88的末端94的直径。第二护套在传送管98的外侧上的部分100可以被紧实或“挤压”以使得在下述传送步骤中第二护套更容易致动。
为了实现可植入装置20从护套元件26到第二护套元件98的传送，图15中所示的可植入装置20、护套元件26、以及传送漏斗88组合放置成与图16所示的第二护套元件96和传送管98处于邻抵的定向，如图17所示。通过对护套元件26施加拉伸92并同时对第二护套元件98施加拉伸102，如图17所示，可植入装置20将从传送漏斗88和护套元件26传送到传送管98和第二护套元件96内。该传送在图17中示出部分完成。
一旦可植入装置20完全传送到第二护套元件96内，则装置20和第二护套98可从传送管移除，如图18所示。可植入装置20现包含在小直径和/或包含在比图3所示的装置和护套更薄壁厚的护套内。在该阶段，组合的装置和护套可如参照先前图4至6所描述那样进一步处理。
从图15至18的该描述应理解，本发明可通过多种方式实践，由此可植入装置可在制造过程期间部分紧实到一个或多个中间直径。
如已经解释的，本发明提供优于现有医疗装置部署设备的更多优点，包括但不限于：
(1)本发明提供了在体内递送期间保护医疗装置的递送系统，同时提供可缩放以在各种可植入装置形状和尺寸上使用的简单、精确且可靠的装置部署。
(2)递送系统构造成使得加载和部署(展开)力不直接与装置直径、长度或设计相关，因此允许跨越各种递送装置构造和产品线的更通用递送系统。在这方面，约束可植入装置并部署(展开)可植入装置所需的力可与可植入装置的长度和其它特性无关。
(3)通过采用护套元件以在可植入装置的外侧上呈现更一致的表面，部署力在递送期间可以更平稳，从而使导管运动最少(例如，可以避免由于可植入装置与约束件之间的不利相互作用而增加递送力)。类似地，本发明可适应具有不规则特征(例如扇形孔、倒钩、锚固件、顶点和可能否则与部署设备的平稳操作干涉的其它特征)的装置的部署。
(4)护套元件的使用可有助于减小装置递送轮廓，这既通过允许紧实力与装置纵向拉伸强度无关联、又通过在可植入装置的外侧上提供可能更润滑的表面而允许更方便装置的紧实来实现。通过消除加载期间装置的直接张紧，本发明还允许较低的可植入装置质量和较低轮廓。
(5)本发明可构造成将各递送线包含在护套元件内，从而减少或消除部署期间线的“弓弦现象”。
(6)通过在装载之前封装可植入装置并保持其封装直到部署(展开)，本发明赋予可植入装置以最小应力。对于药物递送装置，这可减少制造和使用时在搬运(操作)装置期间的药物损失和颗粒化。在这方面，装置的封装可在装置装载和安装期间减少或消除装置与工具之间的接触，并还可在递送和部署(展开)期间将装置与表面剪切和其它损坏隔离开。
对于本领域技术人员来说明显的是，可在本发明内作出各种修改和变型而不脱离本发明的精神或范围。因此，本发明旨在涵盖其任何改型和变型，只要它们落在所附权利要求及其等同物的范围内即可。

Claims (32)

1.一种用于可植入医疗装置的部署系统，包括：
可膨胀医疗装置，所述可膨胀医疗装置具有较大的部署直径和用于递送的较小的紧实直径；
护套，所述护套围绕较小的紧实的医疗装置，所述护套外翻回到自身上，其中所述护套的外部围绕所述护套的内部；
细丝状约束构件，所述细丝状约束构件位于所述护套的所述内部与外部之间，其中所述医疗装置通过对所述护套和所述细丝状约束构件同时施加致动力而部署成较大直径。
2.如权利要求1所述的部署系统，其特征在于，所述可膨胀医疗装置是自膨胀的。
3.如权利要求1所述的部署系统，其特征在于，所述护套呈管状，且所述护套的所述外部同轴围绕所述护套的所述内部。
4.如权利要求1所述的部署系统，其特征在于，同时致动力致使所述护套和所述约束构件以不同速率撤回。
5.如权利要求4所述的部署系统，其特征在于，两个不同速率包括变化的差别速率。
6.如权利要求1所述的部署系统，其特征在于，所述可植入装置包括生物活性涂层，且所述护套用于在所述装置操作期间保护所述涂层。
7.如权利要求6所述的部署系统，其特征在于，所述生物活性涂层包括药物涂层。
8.如权利要求1所述的部署系统，其特征在于，所述护套包括螺旋状打褶的护套。
9.如权利要求1所述的部署系统，其特征在于，所述可植入装置具有有限的轴向长度，并通过由所述护套提供的增大的轴向长度在递送期间受到免于损坏的保护。
10.如权利要求1所述的部署系统，其特征在于，所述护套和约束构件的相互作用用于将部署力与所述可植入装置的长度脱开关联。
11.如权利要求1所述的部署系统，其特征在于，所述约束构件在施加拉伸力时散开。
12.如权利要求1所述的部署系统，其特征在于，所述护套包括在施加拉伸力时散开的细丝。
13.一种用于可植入医疗装置的部署系统，包括：
可膨胀医疗装置，所述可膨胀医疗装置具有较大的部署直径和用于递送的较小的紧实直径；
第一护套，所述第一护套围绕较小的紧实的自膨胀医疗装置，所述护套外翻回到自身上，其中所述第一护套的外部围绕所述第一护套的内部；
第二护套，所述第二护套位于所述第一护套的所述内部与外部之间，其中所述第一护套和所述第二护套通过对所述第一护套和所述叠护套施加两个分开的拉伸力而被移除。
14.如权利要求13所述的部署系统，其特征在于，所述可膨胀医疗装置是自膨胀的。
15.如权利要求13所述的部署系统，其特征在于，所述第一护套的所述外部同轴地围绕所述第一护套的所述内部。
16.如权利要求13所述的部署系统，其特征在于，两个分开的拉伸力致使所述第一护套和第二护套以两个不同速率撤回。
17.如权利要求16所述的部署系统，其特征在于，所述两个不同速率包括变化的差别速率。
18.如权利要求13所述的部署系统，其特征在于，所述可植入装置包括生物活性涂层，且所述第一护套用于在所述装置递送期间保护所述涂层。
19.如权利要求18所述的部署系统，其特征在于，所述生物活性涂层包括药物涂层。
20.如权利要求13所述的部署系统，其特征在于，所述第一护套包括螺旋状打褶的护套。
21.如权利要求13所述的部署系统，其特征在于，所述可植入装置具有有限的轴向长度，并通过由所述第一护套提供的增大的轴向长度在递送期间受到免于损坏的保护。
22.如权利要求13所述的部署系统，其特征在于，所述第一护套和所述第二护套的相互作用用于将部署力与所述可植入装置的长度脱开关联。
23.如权利要求13所述的部署系统，其特征在于，所述第二护套包括在施加拉伸力时散开的细丝。
24.如权利要求13所述的部署系统，其特征在于，所述第一护套包括在施加拉伸力时散开的细丝。
25.一种将可植入装置加载在部署系统上的方法，包括：
提供可植入装置；
将所述可植入装置放置在护套元件内，所述护套元件包括延伸超过所述可植入装置的段；
提供漏斗和约束元件；
在所述护套的所述段上施加拉伸力以将所述护套元件和所述可植入装置拉过所述漏斗，从而将所述可植入装置紧实在所述护套元件内并进入所述约束元件，从而将所述可植入装置约束在紧实状态下；
其中所述护套元件和约束元件构造成在使用时被移除以部署所述可植入装置。
26.如权利要求25所述的方法，其特征在于，还包括：
在所述可植入装置通过所述漏斗紧实之后，所述可植入装置在使用之前进一步被紧实。
27.如权利要求25所述的方法，其特征在于，还包括：
提供用于所述护套元件的第一部署线，并提供用于所述约束元件的第二部署线；以及
将所述第一部署线和所述第二部署线布置成基本上同时致动以实现部署。
28.一种医疗装置部署系统，包括：
第一护套和第二护套，其中所述第一和第二护套中的每个通过对连接到每个所述第一和第二护套的拉伸构件施加拉伸力而不成比例地被致动，其中在通过施加单个输入力部署时，所述输入力可变地分布在所述拉伸构件之间。
29.如权利要求28所述的部署系统，其特征在于，输入力通过使用滑轮可变地分布在所述拉伸构件之间。
30.如权利要求28所述的部署系统，其特征在于，输入力通过使用差动元件可变地分布在所述拉伸构件之间。
31.如权利要求28所述的部署系统，其特征在于，输入力通过使用离合机构可变地分布在所述拉伸构件之间。
32.一种医疗装置部署系统，包括：
通过转动行星滚动元件而啮合的两个或多个滑轮，其中所述滑轮中的每个构造成积聚部署线，其中所述部署线致动医疗装置的部署。
CN201580011920.6A 2014-03-06 2015-03-06 可植入医疗装置约束和部署设备 Active CN106102596B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910476286.3A CN110051399B (zh) 2014-03-06 2015-03-06 可植入医疗装置约束和部署设备

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461949100P 2014-03-06 2014-03-06
US61/949,100 2014-03-06
US14/639,699 US10966850B2 (en) 2014-03-06 2015-03-05 Implantable medical device constraint and deployment apparatus
US14/639,699 2015-03-05
PCT/US2015/019271 WO2015134917A2 (en) 2014-03-06 2015-03-06 Implantable medical device constraint and deployment apparatus

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201910476286.3A Division CN110051399B (zh) 2014-03-06 2015-03-06 可植入医疗装置约束和部署设备

Publications (2)

Publication Number Publication Date
CN106102596A true CN106102596A (zh) 2016-11-09
CN106102596B CN106102596B (zh) 2019-06-28

Family

ID=54016261

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201580011920.6A Active CN106102596B (zh) 2014-03-06 2015-03-06 可植入医疗装置约束和部署设备
CN201910476286.3A Active CN110051399B (zh) 2014-03-06 2015-03-06 可植入医疗装置约束和部署设备

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201910476286.3A Active CN110051399B (zh) 2014-03-06 2015-03-06 可植入医疗装置约束和部署设备

Country Status (10)

Country Link
US (3) US10966850B2 (zh)
EP (2) EP4049632A3 (zh)
JP (3) JP6870986B2 (zh)
KR (1) KR20160130268A (zh)
CN (2) CN106102596B (zh)
AU (2) AU2015226907B2 (zh)
BR (1) BR112016020044A8 (zh)
CA (2) CA2940704C (zh)
ES (1) ES2924403T3 (zh)
WO (1) WO2015134917A2 (zh)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110292462A (zh) * 2018-03-21 2019-10-01 美敦力瓦斯科尔勒公司 变速缩回机构递送系统和方法
CN110381888A (zh) * 2017-03-09 2019-10-25 美敦力瓦斯科尔勒公司 用于带支架的假体递送装置的张力管理装置
CN111212619A (zh) * 2017-10-11 2020-05-29 W.L.戈尔及同仁股份有限公司 可植入医疗设备约束和展开装置
CN112638320A (zh) * 2018-08-31 2021-04-09 W.L.戈尔及同仁股份有限公司 用于使可植入医疗装置转向的设备、系统和方法
CN112789012A (zh) * 2018-10-05 2021-05-11 W.L.戈尔及同仁股份有限公司 约束机构和相关联的方法
CN112789009A (zh) * 2018-10-05 2021-05-11 W.L.戈尔及同仁股份有限公司 用于选择性展开的约束机构及相关联的方法
CN113038907A (zh) * 2018-07-06 2021-06-25 库克医学技术有限责任公司 储存装置、装载装置、递送系统、套件、以及相关方法
US11801155B2 (en) 2014-03-06 2023-10-31 W. L. Gore & Associates, Inc. Implantable medical device constraint and deployment apparatus
US11857407B2 (en) 2014-01-10 2024-01-02 W. L. Gore & Associates, Inc. Implantable intraluminal device
US11903856B1 (en) 2013-03-05 2024-02-20 W. L. Gore & Associates, Inc. Tapered sleeve
US12076227B2 (en) 2012-03-13 2024-09-03 W. L. Gore & Associates, Inc. External steerable fiber for use in endoluminal deployment of expandable devices
US12257166B2 (en) 2011-11-14 2025-03-25 W. L. Gore & Associates, Inc. External steerable fiber for use in endoluminal deployment of expandable devices

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10213329B2 (en) 2011-08-12 2019-02-26 W. L. Gore & Associates, Inc. Evertable sheath devices, systems, and methods
US9993251B2 (en) 2014-05-02 2018-06-12 W. L. Gore & Associates, Inc. Anastomosis devices
US11712230B2 (en) 2014-05-02 2023-08-01 W. L. Gore & Associates, Inc. Occluder and anastomosis devices
US11724075B2 (en) * 2017-04-18 2023-08-15 W. L. Gore & Associates, Inc. Deployment constraining sheath that enables staged deployment by device section
US10406012B2 (en) * 2017-04-26 2019-09-10 Medtronic Vascular, Inc. Mechanical delivery systems for an endovascular device
EP3806783B1 (en) * 2018-06-14 2025-03-05 W. L. Gore & Associates, Inc. System and method for on-device constraining mechanism construction
KR102610812B1 (ko) * 2019-02-15 2023-12-06 보스톤 싸이엔티픽 싸이메드 인코포레이티드 스텐트 전달 시스템
CN113473934A (zh) * 2019-02-22 2021-10-01 W.L.戈尔及同仁股份有限公司 致动线储存系统和方法
US11259944B2 (en) * 2019-06-27 2022-03-01 Cook Medical Technologies Llc Stent deployment system with unwrapping deployment constraint
US20210321995A1 (en) * 2020-04-17 2021-10-21 Boston Scientific Scimed, Inc. Devices, systems, and methods for accessing a body lumen
CN116056668A (zh) * 2020-06-11 2023-05-02 爱德华兹生命科学公司 用于假体瓣膜递送设备的刚性编织物构件
WO2022140635A1 (en) * 2020-12-23 2022-06-30 Boston Scientific Scimed Inc. Facilitate delivery of devices with high friction - braid
CN117045303B (zh) * 2023-08-16 2024-02-02 南京思脉德医疗科技有限公司 一种栓塞弹簧圈输送系统的换丝装置

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6315792B1 (en) * 1998-06-15 2001-11-13 Gore Enterprise Holdings, Inc. Remotely removable covering and support
US20050240254A1 (en) * 2004-04-27 2005-10-27 Michael Austin Stent delivery system
US20080281398A1 (en) * 2007-05-07 2008-11-13 Koss Alexander K Stent delivery and deployment system
US20090182411A1 (en) * 2008-01-15 2009-07-16 Irwin Craig W Pleated deployment sheath
CN104023677A (zh) * 2011-08-12 2014-09-03 W.L.戈尔及同仁股份有限公司 可外翻套管装置、系统和方法

Family Cites Families (199)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR8208063A (pt) 1981-09-16 1984-01-10 Hans Ivar Wallsten Dispositivo para aplicacao em vasos sanguineos ou outros locais de dificil acesso e seu emprego
IT1186142B (it) 1984-12-05 1987-11-18 Medinvent Sa Dispositivo di impiantazione transluminale
SE455834B (sv) 1986-10-31 1988-08-15 Medinvent Sa Anordning for transluminal implantation av en i huvudsak rorformig, radiellt expanderbar protes
US4921479A (en) 1987-10-02 1990-05-01 Joseph Grayzel Catheter sheath with longitudinal seam
US5064435A (en) 1990-06-28 1991-11-12 Schneider (Usa) Inc. Self-expanding prosthesis having stable axial length
US5389100A (en) 1991-11-06 1995-02-14 Imagyn Medical, Inc. Controller for manipulation of instruments within a catheter
FR2688401B1 (fr) 1992-03-12 1998-02-27 Thierry Richard Endoprothese expansible pour organe tubulaire humain ou animal, et outil de mise en place.
US5425765A (en) 1993-06-25 1995-06-20 Tiefenbrun; Jonathan Surgical bypass method
US5571135A (en) * 1993-10-22 1996-11-05 Scimed Life Systems Inc. Stent delivery apparatus and method
US5989280A (en) * 1993-10-22 1999-11-23 Scimed Lifesystems, Inc Stent delivery apparatus and method
US5445646A (en) * 1993-10-22 1995-08-29 Scimed Lifesystems, Inc. Single layer hydraulic sheath stent delivery apparatus and method
EP1010406B1 (en) 1994-06-08 2005-02-02 Cardiovascular Concepts, Inc. Endoluminal graft
US5824041A (en) 1994-06-08 1998-10-20 Medtronic, Inc. Apparatus and methods for placement and repositioning of intraluminal prostheses
US6264684B1 (en) 1995-03-10 2001-07-24 Impra, Inc., A Subsidiary Of C.R. Bard, Inc. Helically supported graft
US5647857A (en) * 1995-03-16 1997-07-15 Endotex Interventional Systems, Inc. Protective intraluminal sheath
DE69626108T2 (de) * 1995-04-14 2003-11-20 Boston Scientific Ltd., St. Michael Stentanbringungsvorrichtung mit rollmembran
DE19531659C2 (de) 1995-08-29 1998-07-02 Ernst Peter Prof Dr M Strecker Stent
GB9518400D0 (en) 1995-09-08 1995-11-08 Anson Medical Ltd A surgical graft/stent system
US6042605A (en) 1995-12-14 2000-03-28 Gore Enterprose Holdings, Inc. Kink resistant stent-graft
EP0950385A3 (en) 1995-12-14 1999-10-27 Prograft Medical, Inc. Stent-graft deployment apparatus and method
US5928279A (en) 1996-07-03 1999-07-27 Baxter International Inc. Stented, radially expandable, tubular PTFE grafts
CA2211249C (en) 1996-07-24 2007-07-17 Cordis Corporation Balloon catheter and methods of use
CA2263672A1 (en) 1996-08-26 1998-03-05 Transvascular, Inc. Methods and apparatus for transmyocardial direct coronary revascularization
US6254628B1 (en) * 1996-12-09 2001-07-03 Micro Therapeutics, Inc. Intracranial stent
EP2298241A3 (en) 1996-12-03 2011-11-02 Atrium Medical Corporation Multi-stage prothesis
US6352561B1 (en) 1996-12-23 2002-03-05 W. L. Gore & Associates Implant deployment apparatus
US6004328A (en) 1997-06-19 1999-12-21 Solar; Ronald J. Radially expandable intraluminal stent and delivery catheter therefore and method of using the same
US20100030256A1 (en) 1997-11-12 2010-02-04 Genesis Technologies Llc Medical Devices and Methods
AUPP083597A0 (en) 1997-12-10 1998-01-08 William A Cook Australia Pty Ltd Endoluminal aortic stents
JP4197842B2 (ja) 1998-01-26 2008-12-17 アンソン メディカル リミテッド 強化移植片
US6203550B1 (en) 1998-09-30 2001-03-20 Medtronic, Inc. Disposable delivery device for endoluminal prostheses
US6544278B1 (en) * 1998-11-06 2003-04-08 Scimed Life Systems, Inc. Rolling membrane stent delivery system
US6059813A (en) 1998-11-06 2000-05-09 Scimed Life Systems, Inc. Rolling membrane stent delivery system
US6113608A (en) 1998-11-20 2000-09-05 Scimed Life Systems, Inc. Stent delivery device
DE60037691T2 (de) * 1999-01-22 2009-01-02 Gore Enterprise Holdings, Inc., Newark Verfahren zum Zusammendrücken einer Endoprothese
US6398758B1 (en) 1999-02-16 2002-06-04 Stephen C. Jacobsen Medicament delivery system
JP4138144B2 (ja) 1999-03-31 2008-08-20 テルモ株式会社 管腔内留置物
US6428550B1 (en) 1999-05-18 2002-08-06 Cardica, Inc. Sutureless closure and deployment system for connecting blood vessels
US6478814B2 (en) 1999-06-14 2002-11-12 Scimed Life Systems, Inc. Stent securement sleeves and optional coatings and methods of use
US6364904B1 (en) 1999-07-02 2002-04-02 Scimed Life Systems, Inc. Helically formed stent/graft assembly
US6533806B1 (en) 1999-10-01 2003-03-18 Scimed Life Systems, Inc. Balloon yielded delivery system and endovascular graft design for easy deployment
US6383171B1 (en) * 1999-10-12 2002-05-07 Allan Will Methods and devices for protecting a passageway in a body when advancing devices through the passageway
US7201770B2 (en) * 2000-03-21 2007-04-10 Cordis Corporation Everting balloon stent delivery system having tapered leading edge
WO2001083017A1 (en) * 2000-05-02 2001-11-08 Wilson-Cook Medical, Inc. Introducer device for catheters o.t.l. with eversible sleeve
SE522805C2 (sv) * 2000-06-22 2004-03-09 Jan Otto Solem Stentappliceringssystem
US6607552B1 (en) 2000-09-18 2003-08-19 Scimed Life Systems, Inc. Rolling socks
US6733520B2 (en) 2000-09-22 2004-05-11 Scimed Life Systems, Inc. Sandwich striped sleeve for stent delivery
US6645242B1 (en) 2000-12-11 2003-11-11 Stephen F. Quinn Bifurcated side-access intravascular stent graft
US6899727B2 (en) * 2001-01-22 2005-05-31 Gore Enterprise Holdings, Inc. Deployment system for intraluminal devices
US6733521B2 (en) 2001-04-11 2004-05-11 Trivascular, Inc. Delivery system and method for endovascular graft
US6676693B1 (en) 2001-06-27 2004-01-13 Advanced Cardiovascular Systems, Inc. Apparatus and method for delivering a self-expanding stent
US20030004561A1 (en) 2001-06-28 2003-01-02 Steve Bigus Peeling sheath for self-expanding stent
US6949112B1 (en) 2001-07-26 2005-09-27 Advanced Cardiovascular Systems, Inc. Medical device formed of polyester copolymer
AUPR847301A0 (en) 2001-10-26 2001-11-15 Cook Incorporated Endoluminal prostheses for curved lumens
US20060292206A1 (en) 2001-11-26 2006-12-28 Kim Steven W Devices and methods for treatment of vascular aneurysms
US7147656B2 (en) * 2001-12-03 2006-12-12 Xtent, Inc. Apparatus and methods for delivery of braided prostheses
US7147661B2 (en) 2001-12-20 2006-12-12 Boston Scientific Santa Rosa Corp. Radially expandable stent
US20100016943A1 (en) 2001-12-20 2010-01-21 Trivascular2, Inc. Method of delivering advanced endovascular graft
GB0203177D0 (en) 2002-02-11 2002-03-27 Anson Medical Ltd An improved control mechanism for medical catheters
JP4208075B2 (ja) 2002-03-25 2009-01-14 クック インコーポレイティド 二股の／枝分かれした血管用プロテーゼ
US6911039B2 (en) 2002-04-23 2005-06-28 Medtronic Vascular, Inc. Integrated mechanical handle with quick slide mechanism
US6830575B2 (en) * 2002-05-08 2004-12-14 Scimed Life Systems, Inc. Method and device for providing full protection to a stent
JP4624779B2 (ja) 2002-05-16 2011-02-02 クック インコーポレイテッド プロテーゼを係止するフレキシブルな「かえし」
US20040097957A1 (en) * 2002-10-18 2004-05-20 Marc Jaker Medical device, drug delivery and lab sampling system utilizing an inverting sheath technology
US20040087886A1 (en) 2002-10-30 2004-05-06 Scimed Life Systems, Inc. Linearly expandable ureteral stent
GB0327306D0 (en) 2003-11-24 2003-12-24 Angiomed Gmbh & Co Catheter device
US7753945B2 (en) 2003-01-17 2010-07-13 Gore Enterprise Holdings, Inc. Deployment system for an endoluminal device
US7198636B2 (en) 2003-01-17 2007-04-03 Gore Enterprise Holdings, Inc. Deployment system for an endoluminal device
US7318836B2 (en) 2003-03-11 2008-01-15 Boston Scientific Scimed, Inc. Covered stent
US8262671B2 (en) 2003-03-14 2012-09-11 Oscor Inc. Vascular introducer having hemostatic valve with integral seal
US20050049675A1 (en) 2003-03-28 2005-03-03 Board Of Regents, The University Of Texas System Medical devices and related methods
US7530963B2 (en) 2003-04-24 2009-05-12 Wisconsin Alumni Research Foundation Method of maintaining patency of opening in third ventricle floor
EP1501175B1 (en) * 2003-07-01 2006-05-24 Alcatel Method to prevent saturation of an inductor coil and inductor coil circuits for realising such a method
US7651519B2 (en) 2003-09-16 2010-01-26 Cook Incorporated Prosthesis deployment system
US20050059923A1 (en) 2003-09-17 2005-03-17 Ricardo Gamboa Fenestration with intrinsic means of selective closure incorporated to a tubular body and used in interventional cardiovascular procedures
US7425219B2 (en) 2003-10-10 2008-09-16 Arshad Quadri System and method for endoluminal grafting of bifurcated and branched vessels
DE602004018169D1 (de) 2003-10-10 2009-01-15 Cook William Europ Stent-fenster
EP3050542B1 (en) 2003-10-14 2022-03-16 Cook Medical Technologies LLC Introducer for an iliac side branch device
US7695508B2 (en) * 2003-10-16 2010-04-13 Minvasys Sa Catheter system for stenting bifurcated vessels
US20050131515A1 (en) 2003-12-16 2005-06-16 Cully Edward H. Removable stent-graft
US7468070B2 (en) * 2004-01-23 2008-12-23 Boston Scientific Scimed, Inc. Stent delivery catheter
WO2005088437A1 (en) * 2004-03-11 2005-09-22 Redsky Mobile Inc. Restricted user interface navigation
JP2006006648A (ja) 2004-06-25 2006-01-12 Terumo Corp 血管接合具および血管接合装置
US20050288766A1 (en) 2004-06-28 2005-12-29 Xtent, Inc. Devices and methods for controlling expandable prostheses during deployment
US8308789B2 (en) * 2004-07-16 2012-11-13 W. L. Gore & Associates, Inc. Deployment system for intraluminal devices
US7955370B2 (en) * 2004-08-06 2011-06-07 Boston Scientific Scimed, Inc. Stent delivery system
US7393358B2 (en) * 2004-08-17 2008-07-01 Boston Scientific Scimed, Inc. Stent delivery system
CN100352406C (zh) 2004-08-17 2007-12-05 微创医疗器械(上海)有限公司 组合式可任意方向弯曲的覆膜支架
US9706997B2 (en) 2004-08-27 2017-07-18 Rox Medical, Inc. Device and method for establishing an artificial arterio-venous fistula
US7347868B2 (en) * 2004-10-26 2008-03-25 Baronova, Inc. Medical device delivery catheter
US8262720B2 (en) * 2004-12-02 2012-09-11 Nitinol Development Corporation Prosthesis comprising dual tapered stent
US7918880B2 (en) * 2005-02-16 2011-04-05 Boston Scientific Scimed, Inc. Self-expanding stent and delivery system
US7828837B2 (en) 2005-02-17 2010-11-09 Khoury Medical Devices, LLC. Vascular endograft
US7632296B2 (en) 2005-03-03 2009-12-15 Boston Scientific Scimed, Inc. Rolling membrane with hydraulic recapture means for self expanding stent
FR2885794B1 (fr) * 2005-05-19 2007-08-17 Perouse Soc Par Actions Simpli Necessaire de largage d'un organe de traitement d'une cavite et procede de preparation d'un organe de traitement associe
US7938851B2 (en) 2005-06-08 2011-05-10 Xtent, Inc. Devices and methods for operating and controlling interventional apparatus
US7935141B2 (en) * 2005-08-17 2011-05-03 C. R. Bard, Inc. Variable speed stent delivery system
JP5000656B2 (ja) 2005-08-22 2012-08-15 インセプト・リミテッド・ライアビリティ・カンパニー フレア展開ステント、ならびにこれを製造・使用する装置および方法
US20070142904A1 (en) 2005-12-20 2007-06-21 Boston Scientific Scimed, Inc. Bifurcated stent with multiple locations for side branch access
TW200732412A (en) * 2006-02-23 2007-09-01 Pont Taiwan Ltd Du Non-halogen composition having phosphor-containing epoxy resin
US20070208350A1 (en) * 2006-03-06 2007-09-06 Gunderson Richard C Implantable medical endoprosthesis delivery systems
JP2009530060A (ja) 2006-03-20 2009-08-27 エックステント・インコーポレーテッド 連結されたプロテーゼセグメントの展開装置及び方法
US9211206B2 (en) * 2006-04-13 2015-12-15 Medtronic Vascular, Inc. Short handle for a long stent
US20080028139A1 (en) * 2006-07-27 2008-01-31 Cypher Robert E Content-addressable memory that supports a priority ordering between banks
US9585743B2 (en) 2006-07-31 2017-03-07 Edwards Lifesciences Cardiaq Llc Surgical implant devices and methods for their manufacture and use
US20080140173A1 (en) 2006-08-07 2008-06-12 Sherif Eskaros Non-shortening wrapped balloon
GB0618516D0 (en) 2006-09-20 2006-11-01 Angiomed Ag Hand-held actuator device
US8257431B2 (en) 2006-11-01 2012-09-04 Boston Scientific Scimed, Inc. Multi-furcated ePTFE grafts and stent-graft prostheses and methods of making the same
US8167926B2 (en) 2006-11-07 2012-05-01 Cook Medical Technologies Llc Fenestration for stent graft arrangements and stent graft including the same
US7655034B2 (en) 2006-11-14 2010-02-02 Medtronic Vascular, Inc. Stent-graft with anchoring pins
US20080140003A1 (en) * 2006-12-06 2008-06-12 Advanced Cardiovascular Systems, Inc. Balloon catheter having a regrooming sheath and method for collapsing an expanded medical device
US20080167705A1 (en) * 2007-01-10 2008-07-10 Cook Incorporated Short wire stent delivery system with splittable outer sheath
US8088154B2 (en) * 2007-03-31 2012-01-03 Cook Medical Technologies Llc Medical device delivery system with sheath separation
US8540760B2 (en) 2007-07-11 2013-09-24 Cook Medical Technologies Llc Tubular devices having reversible components for deployment of endoluminal occluders and related methods and systems
US8617114B2 (en) * 2007-07-13 2013-12-31 Abbott Cardiovascular Systems Inc. Drug coated balloon catheter
US8690823B2 (en) * 2007-07-13 2014-04-08 Abbott Cardiovascular Systems Inc. Drug coated balloon catheter
US9149379B2 (en) 2007-07-16 2015-10-06 Cook Medical Technologies Llc Delivery device
US20090043376A1 (en) 2007-08-08 2009-02-12 Hamer Rochelle M Endoluminal Prosthetic Conduit Systems and Method of Coupling
US20090099638A1 (en) 2007-10-11 2009-04-16 Med Institute, Inc. Motorized deployment system
EP2227185B1 (en) 2007-11-07 2013-05-01 Cook Medical Technologies LLC Apparatus for introducing expandable intraluminal prosthesis
US8328861B2 (en) 2007-11-16 2012-12-11 Trivascular, Inc. Delivery system and method for bifurcated graft
US20090143759A1 (en) 2007-11-30 2009-06-04 Jacques Van Dam Methods, Devices, Kits and Systems for Defunctionalizing the Cystic Duct
US8758421B2 (en) * 2008-01-30 2014-06-24 Boston Scientific Scimed, Inc. Medical systems and related methods
WO2009102441A1 (en) 2008-02-11 2009-08-20 William A. Cook Australia Pty. Ltd. Curve forming apparatus and curvable stent graft
DE102008012113A1 (de) 2008-03-02 2009-09-03 Transcatheter Technologies Gmbh Stent, welcher vom expandierten Zustand erneut im Durchmesser kontrolliert verringerbar ist
US20100036360A1 (en) 2008-04-25 2010-02-11 Nellix, Inc. Stent graft delivery system
DE102008021060A1 (de) * 2008-04-26 2009-10-29 Biotronik Vi Patent Ag Einführvorrichtung mit einer Freisetzeinrichtung zur Freisetzung eines von einem Katheter getragenen Gegenstandes sowie Freisetzeinrichtung einer Einführvorrichtung
WO2009145901A1 (en) 2008-05-29 2009-12-03 Med Institute, Inc. Low profile composite endoluminal prostheses
TW201000160A (en) 2008-06-25 2010-01-01 Univ Nat Taiwan The control system of catheter feeder
JP5134729B2 (ja) 2008-07-01 2013-01-30 エンドロジックス、インク カテーテルシステム
EP2328524B1 (en) * 2008-07-02 2019-01-16 Cook Medical Technologies LLC Deployment assembly
US20100003647A1 (en) * 2008-07-04 2010-01-07 Wendell Brown System and Method for Automated Meal Recommendations
US8109985B2 (en) 2008-07-23 2012-02-07 Boston Scientific Scimed, Inc. Occlusion crossing device and method
US7976574B2 (en) * 2008-08-08 2011-07-12 Advanced Cardiovascular Systems, Inc. Delivery system with variable delivery rate for deploying a medical device
US8721714B2 (en) * 2008-09-17 2014-05-13 Medtronic Corevalve Llc Delivery system for deployment of medical devices
US8790387B2 (en) * 2008-10-10 2014-07-29 Edwards Lifesciences Corporation Expandable sheath for introducing an endovascular delivery device into a body
WO2010048052A1 (en) 2008-10-22 2010-04-29 Boston Scientific Scimed, Inc. Shape memory tubular stent with grooves
GB2464978B (en) 2008-10-31 2010-10-20 Cook William Europ Introducer for deploying a stent graft in a curved lumen
EP2352464B1 (en) 2008-12-03 2013-01-23 Angiomed GmbH & Co. Medizintechnik KG Retractable catheter
GB0822110D0 (en) 2008-12-03 2009-01-07 Angiomed Ag Catheter sheath for implant delivery
GB0822106D0 (en) 2008-12-03 2009-01-07 Angiomed Ag Retractable catheter
GB0823716D0 (en) 2008-12-31 2009-02-04 Angiomed Ag Stent delivery device with rolling stent retaining sheath
US8326437B2 (en) * 2009-03-04 2012-12-04 W. L. Gore & Associates, Inc. Atraumatic lead removal sheath
US9301863B2 (en) 2009-03-10 2016-04-05 Medtronic Vascular, Inc. Prosthesis delivery apparatus and methods
US8968381B2 (en) * 2009-04-15 2015-03-03 Cook Medical Technologies Llc Everting deployment system and handle
US20110009943A1 (en) 2009-07-09 2011-01-13 Paul Ram H Delivery system with medical device release by evertable sleeve
US8936634B2 (en) * 2009-07-15 2015-01-20 W. L. Gore & Associates, Inc. Self constraining radially expandable medical devices
US8435282B2 (en) * 2009-07-15 2013-05-07 W. L. Gore & Associates, Inc. Tube with reverse necking properties
WO2011017189A1 (en) * 2009-08-04 2011-02-10 Wilson-Cook Medical Inc. Roll sleeve mechanism for proximal release stent delivery device
EP2490629B1 (en) 2009-10-20 2019-05-22 Cook Medical Technologies, LLC Rotational controlled deployment device
US20110118817A1 (en) * 2009-11-17 2011-05-19 Boston Scientific Scimed, Inc. Stent delivery system
US20110118765A1 (en) 2009-11-18 2011-05-19 Aguirre Andres F Anastomosis stent
GB0921237D0 (en) 2009-12-03 2010-01-20 Angiomed Ag Stent device delivery system and method of making such
GB0921236D0 (en) 2009-12-03 2010-01-20 Angiomed Ag Stent device delivery system and method of making such
US8016872B2 (en) * 2009-12-22 2011-09-13 Cook Medical Technologies Llc Deployment and dilation with an expandable roll sock delivery system
DE102009060228B4 (de) 2009-12-23 2014-12-04 Acandis Gmbh & Co. Kg Medizinische Vorrichtungen
US20120296408A1 (en) 2010-01-25 2012-11-22 Jones Donald K Methods and systems for performing vascular reconstruction
US20110208292A1 (en) 2010-02-19 2011-08-25 Abbott Laboratories Hinged sheath assembly and method of use
US9226826B2 (en) * 2010-02-24 2016-01-05 Medtronic, Inc. Transcatheter valve structure and methods for valve delivery
US9119738B2 (en) 2010-06-28 2015-09-01 Colibri Heart Valve Llc Method and apparatus for the endoluminal delivery of intravascular devices
US8337542B2 (en) * 2010-07-14 2012-12-25 Cook Medical Technologies Llc Delivery system for simultaneous deployment of intraluminal device
EP2629706B1 (en) 2010-10-21 2017-08-16 Boston Scientific Scimed, Inc. Stent delivery system with a rolling membrane
GB201017834D0 (en) * 2010-10-21 2010-12-01 Angiomed Ag System to deliver a bodily implant
US9468547B2 (en) 2010-11-11 2016-10-18 W. L. Gore & Associates, Inc. Deployment of endoluminal devices
US9414944B2 (en) * 2010-11-11 2016-08-16 W. L. Gore & Associates, Inc. Deployment sleeve shortening mechanism
JP2012105188A (ja) 2010-11-12 2012-05-31 Sony Corp 画像出力装置、画像出力方法、画像処理装置、画像処理方法、プログラム、および撮像装置
US8753386B2 (en) 2010-11-15 2014-06-17 W. L. Gore & Associates, Inc. Stent-graft having facing side branch portals
US20140018610A1 (en) * 2010-12-20 2014-01-16 Walter von Pechmann Endoscopic mesh delivery system with integral mesh stabilizer and vaginal probe
US8657866B2 (en) * 2010-12-22 2014-02-25 Cook Medical Technologies Llc Emergency vascular repair prosthesis deployment system
US8641752B1 (en) * 2011-01-20 2014-02-04 W. L. Gore & Associates, Inc. Integrated sheath and deployment
US9114000B2 (en) 2011-03-14 2015-08-25 Cook Medical Technologies Llc Apparatus and methods to enhance bonding in endoluminal prostheses
US8945212B2 (en) 2011-04-01 2015-02-03 W. L. Gore & Associates, Inc. Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom
CN102166142A (zh) * 2011-04-07 2011-08-31 北京畅想天行医疗技术有限公司 十二指肠-空肠内置套管输送器
US10335296B2 (en) 2011-05-17 2019-07-02 The University Of Kentucky Research Foundation Graft within a graft endoluminal graft
ES2568377T3 (es) 2011-06-21 2016-04-28 Endospan Ltd Sistema endovascular con endoprótesis que solapan circunferencialmente
RU2013157208A (ru) 2011-06-24 2015-07-27 Тейджин Арамид Б.В. Параллельный синтетический жгут
KR101311756B1 (ko) 2011-07-06 2013-09-26 신경민 인체 기관의 인접 조직 연결 시술용 스텐트
AU2012209013B2 (en) 2011-08-02 2013-11-14 Cook Medical Technologies Llc Delivery device having a variable diameter introducer sheath
JP5717592B2 (ja) 2011-08-31 2015-05-13 Ｊｕｎｋｅｎ Ｍｅｄｉｃａｌ株式会社 管状器官の治療装置
EP2604233A3 (de) 2011-12-14 2013-12-11 Biotronik AG Freigabevorrichtung zum Lösen eines medizinischen Implantats von einen Katheter und Katheter mit einer Freigabevorrichtung sowie Verfahren zum Herstellen eines Klemmkörpers einer Freigabevorrichtung zum Lösen eines medizinischen Implantats von einen Katheter und Katheter mit einer Freigabevorrichtung sowie Verfahren zum Herstellen eines Klemmkörpers einer Freigabevorrichtung und Verfahren zum Klemmen eines Imp-lantats in einem solchen
US9375308B2 (en) 2012-03-13 2016-06-28 W. L. Gore & Associates, Inc. External steerable fiber for use in endoluminal deployment of expandable devices
US9370413B2 (en) 2012-04-12 2016-06-21 Sanford Health Combination double-barreled and debranching stent graft and methods for use
US8968384B2 (en) 2012-04-27 2015-03-03 Medtronic Vascular, Inc. Circumferentially constraining sutures for a stent-graft
US9132025B2 (en) 2012-06-15 2015-09-15 Trivascular, Inc. Bifurcated endovascular prosthesis having tethered contralateral leg
US9387105B2 (en) 2012-11-12 2016-07-12 W.L. Gore & Associates, Inc Sleeves for expandable medical devices and methods of making the same
EP2745812B1 (en) 2012-12-19 2017-01-18 Cook Medical Technologies LLC Repositionable diameter constraints
US10350096B2 (en) 2012-12-26 2019-07-16 Cook Medical Technologies Llc Expandable stent-graft system having diameter reducing connectors
US9308349B2 (en) 2013-02-08 2016-04-12 Vention Medical Advanced Components, Inc. Universal catheter handle
US9763819B1 (en) 2013-03-05 2017-09-19 W. L. Gore & Associates, Inc. Tapered sleeve
US9254204B2 (en) 2013-03-15 2016-02-09 Cook Medical Technologies Llc Stents having barbs protected during delivery
CN105188827B (zh) 2013-05-07 2018-10-16 圣犹达医疗用品电生理部门有限公司 用于可偏转导管的转向致动器
US9445928B2 (en) * 2013-05-30 2016-09-20 Medtronic Vascular, Inc. Delivery system having a single handed deployment handle for a retractable outer sheath
US9907641B2 (en) 2014-01-10 2018-03-06 W. L. Gore & Associates, Inc. Implantable intraluminal device
US10966850B2 (en) 2014-03-06 2021-04-06 W. L. Gore & Associates, Inc. Implantable medical device constraint and deployment apparatus
US10195064B2 (en) 2014-08-15 2019-02-05 W. L. Gore & Associates, Inc. Endoprosthesis delivery systems with improved retraction
EP3028680B1 (en) 2014-12-04 2017-11-29 Cook Medical Technologies LLC Delivery device handle assembly for the sequential deployment of a prosthesis
US10231815B2 (en) 2015-01-16 2019-03-19 Cook Medical Technologies Llc Spiral bird's nest filter
US20170281382A1 (en) 2016-04-05 2017-10-05 Bolton Medical, Inc. Delivery systems with introducer and distal sheaths and methods of use
CN111212619B (zh) 2017-10-11 2023-07-25 W.L.戈尔及同仁股份有限公司 可植入医疗设备约束和展开装置

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6315792B1 (en) * 1998-06-15 2001-11-13 Gore Enterprise Holdings, Inc. Remotely removable covering and support
US20050240254A1 (en) * 2004-04-27 2005-10-27 Michael Austin Stent delivery system
US20080281398A1 (en) * 2007-05-07 2008-11-13 Koss Alexander K Stent delivery and deployment system
US20090182411A1 (en) * 2008-01-15 2009-07-16 Irwin Craig W Pleated deployment sheath
CN104023677A (zh) * 2011-08-12 2014-09-03 W.L.戈尔及同仁股份有限公司 可外翻套管装置、系统和方法

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12257166B2 (en) 2011-11-14 2025-03-25 W. L. Gore & Associates, Inc. External steerable fiber for use in endoluminal deployment of expandable devices
US12076227B2 (en) 2012-03-13 2024-09-03 W. L. Gore & Associates, Inc. External steerable fiber for use in endoluminal deployment of expandable devices
US11903856B1 (en) 2013-03-05 2024-02-20 W. L. Gore & Associates, Inc. Tapered sleeve
US11857407B2 (en) 2014-01-10 2024-01-02 W. L. Gore & Associates, Inc. Implantable intraluminal device
US11801155B2 (en) 2014-03-06 2023-10-31 W. L. Gore & Associates, Inc. Implantable medical device constraint and deployment apparatus
CN110381888A (zh) * 2017-03-09 2019-10-25 美敦力瓦斯科尔勒公司 用于带支架的假体递送装置的张力管理装置
CN111212619A (zh) * 2017-10-11 2020-05-29 W.L.戈尔及同仁股份有限公司 可植入医疗设备约束和展开装置
US11540933B2 (en) 2017-10-11 2023-01-03 W. L. Gore & Associates, Inc. Implantable medical device constraint and deployment apparatus
CN110292462A (zh) * 2018-03-21 2019-10-01 美敦力瓦斯科尔勒公司 变速缩回机构递送系统和方法
CN113038907A (zh) * 2018-07-06 2021-06-25 库克医学技术有限责任公司 储存装置、装载装置、递送系统、套件、以及相关方法
CN112638320A (zh) * 2018-08-31 2021-04-09 W.L.戈尔及同仁股份有限公司 用于使可植入医疗装置转向的设备、系统和方法
CN112789009A (zh) * 2018-10-05 2021-05-11 W.L.戈尔及同仁股份有限公司 用于选择性展开的约束机构及相关联的方法
CN112789012B (zh) * 2018-10-05 2024-06-07 W.L.戈尔及同仁股份有限公司 约束机构和相关联的方法
CN112789012A (zh) * 2018-10-05 2021-05-11 W.L.戈尔及同仁股份有限公司 约束机构和相关联的方法
US12220336B2 (en) 2018-10-05 2025-02-11 W. L. Gore & Associates, Inc. Constraining mechanisms for selective deployment and associated methods

Also Published As

Publication number Publication date
JP2021062229A (ja) 2021-04-22
AU2018202564A1 (en) 2018-05-10
JP2017511725A (ja) 2017-04-27
ES2924403T3 (es) 2022-10-06
CN110051399A (zh) 2019-07-26
CN106102596B (zh) 2019-06-28
CA2940704C (en) 2020-04-21
CA3074339A1 (en) 2015-09-11
KR20160130268A (ko) 2016-11-10
EP3113728A2 (en) 2017-01-11
CA2940704A1 (en) 2015-09-11
WO2015134917A3 (en) 2015-12-03
AU2015226907B2 (en) 2018-01-18
US20210186725A1 (en) 2021-06-24
CA3074339C (en) 2022-12-20
AU2018202564B2 (en) 2019-07-04
EP3113728B1 (en) 2022-05-11
JP7286610B2 (ja) 2023-06-05
EP4049632A3 (en) 2022-12-14
WO2015134917A2 (en) 2015-09-11
JP6870986B2 (ja) 2021-05-12
US20240033115A1 (en) 2024-02-01
US20150250630A1 (en) 2015-09-10
BR112016020044A8 (pt) 2020-03-31
US11801155B2 (en) 2023-10-31
EP4049632A2 (en) 2022-08-31
AU2015226907A1 (en) 2016-10-06
US10966850B2 (en) 2021-04-06
CN110051399B (zh) 2022-04-08
JP2023052544A (ja) 2023-04-11

Similar Documents

Publication Publication Date Title
CN106102596A (zh) 可植入医疗装置约束和部署设备
US11000395B2 (en) Sleeve retraction system
US9610183B2 (en) Friction fiber sleeve retraction system
CN101945623B (zh) 用于修补血管畸形的覆膜支架及相关方法
US10004624B2 (en) Device to release a self-expanding implant
CA2636450A1 (en) Device for rapid repair of body conduits
CN102131481A (zh) 将支架装入护套内的方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant