[go: up one dir, main page]

CN106037669A - Finger bio-photon emission spectral distribution graph drawing device and method thereof - Google Patents

Finger bio-photon emission spectral distribution graph drawing device and method thereof Download PDF

Info

Publication number
CN106037669A
CN106037669A CN201610528225.3A CN201610528225A CN106037669A CN 106037669 A CN106037669 A CN 106037669A CN 201610528225 A CN201610528225 A CN 201610528225A CN 106037669 A CN106037669 A CN 106037669A
Authority
CN
China
Prior art keywords
finger
filter plate
photon
luminous intensity
darkroom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610528225.3A
Other languages
Chinese (zh)
Inventor
韩金祥
杨美娜
黄金昭
庞靖祥
范华
刘艳丽
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shandong Provincial Pharmaceutical Biological Tech Research Center
Original Assignee
Shandong Provincial Pharmaceutical Biological Tech Research Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shandong Provincial Pharmaceutical Biological Tech Research Center filed Critical Shandong Provincial Pharmaceutical Biological Tech Research Center
Priority to CN201610528225.3A priority Critical patent/CN106037669A/en
Publication of CN106037669A publication Critical patent/CN106037669A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062Arrangements for scanning
    • A61B5/0064Body surface scanning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

The invention discloses a finger bio-photon emission spectral distribution graph drawing device and a method thereof. The device comprises a darkroom; holes are formed in the front face of the darkroom; photomultiplier tubes are vertically arranged right above the darkroom; an electrically controlled filter wheel is arranged between the darkroom and the photomultiplier tubes; and a plurality of groups of filters are loaded on the filter wheel. Bio-photons spontaneously generated by a finger extending into the darkroom are transmitted to the photomultiplier tubes after passing through one group of filter and then converted into bio-electricity signals, and the bio-electricity signals obtained after conversion are transmitted to a photon counter by the photomultiplier tubes, and the luminous intensity of the finger is obtained by the photon counter; when the filter is non-loaded, the luminous intensity of the filter is obtained; and the photon counter is also connected with a central processing unit, and the central processing unit is used for receiving the luminous intensity of the finger and the luminous intensity of the filter, and calculating the difference between the luminous intensity of the finger and the luminous intensity of the filter to obtain a finger self-luminous intensity, and obtaining a finger spectral distribution graph according to the finger self-luminous intensity.

Description

A kind of finger biometric photon radiation spectral distribution graph drawing apparatus and method thereof
Technical field
The invention belongs to biophoton emission field of detecting, particularly relate to a kind of finger biometric photon radiation spectral distribution graph Drawing apparatus and method thereof.
Background technology
Biophoton emission during deriving from body intracellular metabolic various biochemical reactions from upper state to lower state The photon that transition is launched, it is the generation biosis at " molecular level ", and it is that organism itself is intrinsic Attribute, is an inherent function of biosystem, carries structure change and functional metabolism shape in body metabolic processes The information of state, this information lies in the middle of its parameters such as intensity, spectral distribution.Biosystem is in the change of molecular level Change, can cause system biological photon radiation in the change of the aspect such as intensity, spectral distribution, it to the change within biosystem and The impact of external environment has the sensitivity of height, and detection and analysis to body superweak luminescence can disclose inside biosystem Details, show external environment minor way.
The spontaneous biophoton emission of human finger is found in the seventies in last century, but currently without just for human finger Spontaneous biophoton emission draws the device of its radiation spectrum profiles.Additionally, due to the radiation of finger spontaneous photon is the most micro- Weak, the device sensitivity of the existing spontaneous bio-photon of detection human finger is low, operation is complicated and poor stability, even endangers people The health of body finger.
Summary of the invention
In order to solve the shortcoming of prior art, the present invention provides a kind of finger biometric photon radiation spectral distribution graph to draw dress Put and method.This device sensitivity is high, simple to operate, it is possible to indicates the state of health intuitively and has quick, clever Quick, reliable and lossless to human finger advantage.
For achieving the above object, the present invention is by the following technical solutions:
A kind of finger biometric photon radiation spectral distribution graph drawing apparatus, including darkroom, the front in described darkroom is provided with Stretching into the hole of staff, the surface in described darkroom is vertically installed with photomultiplier tube, between described darkroom and photomultiplier tube It is also equipped with filter plate wheel, described filter plate wheel carries the filter plate of some groups of different-wavebands;
Filter plate is for when there being finger in darkroom, the bio-photon of generation spontaneous to the finger in darkroom is filtered, And filtered bio-photon be sent to photomultiplier tube carry out being converted into bioelectrical signals, the bioelectrical signals after conversion by Photomultiplier tube is sent to photon counter, obtains finger luminous intensity under arbitrary group of filter plate;
Described filter plate is additionally operable to when in darkroom without finger, and self-luminous produces optical signal, and light self-luminous produced Signal is sent to photon counter by photomultiplier tube, obtains the luminous intensity of arbitrary group of filter plate self;
Described photon counter is also connected with central processing unit, and described central processing unit is used for receiving finger and filters at arbitrary group Luminous intensity under wave plate and the luminous intensity of arbitrary group of filter plate self, and by strong for the luminescence of the finger under same group of filter plate Degree is poor with the luminous intensity of filter plate self, obtains finger self-luminous intensity under specific band, and then draws out finger Spectral distribution graph.
Described hole outer is fixed with black rubber set, for preventing the entrance of ambient.
Described filter plate wheel is the filter plate wheel of Electronic control.
Described finger biometric photon radiation spectral distribution graph drawing apparatus also includes that high voltage power supply, described high voltage power supply are used for Power supply is provided for photomultiplier tube.
The front in described darkroom is provided with dividing plate in being provided with two circular cavities and darkroom, for realizing right-hand man's bio-light Son detects simultaneously.
Described central processing unit is also connected with display screen.
A kind of method of work of finger biometric photon radiation spectral distribution graph drawing apparatus, including:
Stretching in darkroom by hands by hole, the bio-photon of each finger of opponent is tested:
In test process, the bio-photon of the spontaneous generation of finger in darkroom, after arbitrary group of filter plate filtering, passes Delivering to photomultiplier tube and be converted into bioelectrical signals, the bioelectrical signals after conversion is sent to photon counting by photomultiplier tube Device, the bioelectrical signals received is processed by photon counter, obtains finger luminous intensity under arbitrary group of filter plate;
When in darkroom without finger, the optical signals photomultiplier tube of arbitrary group of filter plate self-luminous generation is sent to photon After enumerator, obtain the luminous intensity of arbitrary group of filter plate self;
By poor to the luminous intensity of the finger under same group of filter plate and the luminous intensity of filter plate self, obtain finger and exist Self-luminous intensity under specific band, and then draw out finger spectral distribution graph.
After obtaining finger self-luminous intensity under specific band, also include according to different filter plates in different-waveband Quantum efficiency finger self-luminous intensity under specific band is corrected.
Before the method also includes by hole, hands is stretched into darkroom, temperature regulation is controlled to 20 DEG C and ambient humidity Between 40%-50%.This is done to ensure the accuracy of detection finger self-luminous intensity under specific band.
The invention have the benefit that
(1) front in the darkroom of the present invention is provided with dividing plate in being provided with two circular cavities and darkroom, forms double darkroom, is used for Realize right-hand man's bio-photon is detected simultaneously;And the present invention uses high sensitivity and the photoelectricity times without additional refrigeration Increase the bio-photon that pipe detects each finger of hands, improve the measuring accuracy of whole device and make simple to operate, this Invention can indicate the state of health intuitively and have quick, sensitive, reliable and lossless to human finger advantage.
(2) present invention uses the photomultiplier tube of the surface being vertically mounted on darkroom and is arranged on filter plate wheel The filter plate of some groups of different-wavebands, detects the luminous intensity under arbitrary group of filter plate of the finger in darkroom and arbitrary group of filter The luminous intensity of wave plate self, and by the luminous intensity of the luminous intensity of the finger under same group of filter plate Yu filter plate self Differ from, obtain finger self-luminous intensity under specific band, and then draw out finger spectral distribution graph exactly.
Accompanying drawing explanation
Fig. 1 is assembly of the invention structural representation;
Fig. 2 is the method for work schematic flow sheet of assembly of the invention;
Fig. 3 (a) is the distribution of Healthy People left-hand finger spontaneous photon radiation spectrum;
Fig. 3 (b) Healthy People right finger spontaneous photon radiation spectrum is distributed;
Fig. 3 (c) is as a example by cold patients, left-hand finger spontaneous photon radiation spectrum distribution under morbid state;
Fig. 3 (d) is as a example by cold patients, right finger spontaneous photon radiation spectrum distribution under morbid state.
Wherein, 1, darkroom;2, hole;3, photomultiplier tube;4, filter plate wheel;5, photon counter;6, high voltage power supply;7、 Central processing unit.
Detailed description of the invention
The present invention will be further described with embodiment below in conjunction with the accompanying drawings:
As it is shown in figure 1, the finger biometric photon radiation spectral distribution graph drawing apparatus of the present invention includes darkroom 1, photoelectricity times Increase pipe 3, filter plate wheel 4 and photon counter 5.
Wherein, front, darkroom 1 is provided with the hole stretching into staff, and the surface in darkroom 1 is vertically installed with photomultiplier tube 3, it is also equipped with filter plate wheel 4 between described darkroom 1 and photomultiplier tube 3, described filter plate wheel 4 carries some groups of differences The filter plate of wave band.
Darkroom 1 is the important component part of both hands photon detection system, and it acts on is that the measurement for hand spontaneous photon carries For the environment of complete darkness, it is divided into two the dark lattice in left and right, it is simple to right-hand man detects simultaneously.Owing to the photon of hand radiation is the most micro- Weak, therefore the light seal in darkroom is the best, and to avoid the impact of external stray light, this experiment darkroom used is according to hand Luminous that need custom-made, its inwall and periphery are all through blackening process, such as: to whole darkroom surfaces externally and internally all with pitch-dark Even application.
In the present embodiment, front, darkroom 1 has the circular opening 2 of two a diameter of 10cm, hole 2 outer to be respectively fixed with The black rubber glove of long 25cm, its effect be to ensure that arm after hole stretches into darkroom, the contact position, hole of arm and hole 2 Entrance without ambient;Vertically equipped with two photomultiplier tubes 3 directly over darkroom 1, at darkroom 1 upper surface and photomultiplier tube Take turns 4 equipped with automatically controlled filter plate between 3, built with five groups of filter plates, five groups of filter plates be respectively GG395, GG455, GG495, OG550 and RG610, for the measurement of hand spontaneous photon radiation spectrum.
Photomultiplier tube 3 is the core component of both hands spontaneous photon detecting system, and the height of its sensitivity determines whole The system detectivity to hand faint light.Photomultiplier tube 3 (PMT) is a kind of faint optical signal to be converted into and can be visited The electrooptical device of the signal of telecommunication surveyed, it is received by photo-emissive cathode (photocathode), focusing electrode, dynode and electronics Collectors (anode) etc. form, and its operation principle is when low light irradiation to photocathode, and photocathode inspires photoelectron, these photoelectricity Son is pressed focusing electrode electric field and is entered dynode system, and the multiplication obtained by further Secondary Emission is amplified, then after amplification Electronics with anode collect as signal export.Photomultiplier tube of the present invention is that Britain ET Enterprises produces 9235QA type: diameter 51mm (2-inch), end window type is incident, bialkali photocathode, effective photocathode diameter 48mm, wave spectrum Response range is 290nm-630nm, has the features such as high-gain, quick time response, low dark count rate.This device is used up Electricity multiplier tube, without refrigeration, i.e. use of starting shooting, is greatly saved the time that test waits.
Wherein, filter plate is for when having finger in darkroom 1, and the bio-photon of generation spontaneous to the finger in darkroom 1 enters Row filtering, and filtered bio-photon is sent to photomultiplier tube carries out being converted into bioelectrical signals, the biology after conversion The signal of telecommunication is sent to photon counter 5 by photomultiplier tube 3, obtains finger luminous intensity under arbitrary group of filter plate;
Filter plate is additionally operable to when in darkroom without finger, and self-luminous produces optical signal, and optical signal self-luminous produced It is sent to photon counter 5 by photomultiplier tube 3, obtains the luminous intensity of arbitrary group of filter plate self.
The photon counter 5 used in the present embodiment is the C9744 type that Hamamatsu company of Japan produces, such as Fig. 3 institute Show.This type photon counter 5 can be converted into the single photoelectron in photomultiplier tube 3 by incorporated amplifier and discriminator circuit The digital signal of 5V shows.C9744 type photon counter has high-velocity electrons circuit, can realize the measurement of 107s-1, have ÷ 10 and ÷ 1 two grades, wherein one grade can be selected according to the intensity of measured signal.
Photon counter 5 is also connected with central processing unit 7, and described central processing unit 7 is used for receiving finger and filters at arbitrary group Luminous intensity under wave plate and the luminous intensity of arbitrary group of filter plate self, and by strong for the luminescence of the finger under same group of filter plate Degree is poor with the luminous intensity of filter plate self, obtains finger self-luminous intensity under specific band, and then draws out finger Spectral distribution graph.
Wherein, finger biometric photon radiation spectral distribution graph drawing apparatus also includes high voltage power supply, and described high voltage power supply is used In providing power supply for photomultiplier tube.High voltage power supply in the present embodiment is the PM20SP that Sens-Tech company produces, its effect It is to provide the most adjustable, stable and almost without ripple High voltage output for photomultiplier tube.PM20SP type high voltage power supply passes through one Potentiometer is read in the accurate dialing of individual 10 turns, and to realize output the most adjustable from 0-maximum, has that noise is low, stability is high and short-term The feature of drift.
In specific implementation process, central processing unit is also connected with display screen, and display screen draws out finger for display directly perceived Spectral distribution graph.
The specific works flow process of the finger biometric photon radiation spectral distribution graph drawing apparatus of the present invention is:
(1) prepare before test.Within two hours, opening laboratory air-conditioning in advance, temperature regulates to 20 DEG C, and ambient humidity controls Between 40%-50%.Due to this experiment to be obtained be hand spontaneous photon radiation, therefore experiment before need to carry out secretly hand Adaptation processes to mask the ambient impact on skin delayed luminescence.Before experiment, experimenter must be with normal saline or tap water Hand is cleaned up, after naturally drying, puts on preprepared black glove, quiet wait 30 minutes immediately.
(2) parameter is arranged.Testing results software, now can hear filter plate wheel start rotate, system starts self-inspection, wait be System self-inspection completes, and completes the setting of relevant parameter at operation interface.
(3) test process:
1. after startup self-detection process terminates, before the radiation test of finger spontaneous photon, it is necessary first in test experiments darkroom Noise and the spontaneous fluorescence intensity of different filter plate self.Parameter is arranged ibid.
2., after the dark adaptation time of 30 minutes has arrived, experimenter adjusts posture and sits up straight before experiment porch;
3. the both hands having on black glove are put in experiment magazine, by under glove picking in experiment magazine, it is therefore an objective to keep away Exempt from hand again by external light influence;
4. being respectively placed in by corresponding for right-hand man finger fingertip to be measured fixes at groove immediately below left-right photo multiplier tube camera lens, Then clicking on " Measure ", start counting up, now filter plate state is in " No filter ", a finger tip be completed after more Change another root finger.Finger measuring sequence is as follows: the thumb → forefinger → middle finger → third finger → little finger of toe;
5., after the 3rd pacing amount, change filter plate, obtain GG395, GG455, GG495 successively by above-mentioned measuring method, Measurement data under OG550, RG610 difference filter plate;
6. being measured, data derive, analyzing and processing;
(4) data process.As a example by thumb, first the thumb spontaneous luminescence intensity recorded is deducted making an uproar of filter plate itself Sound, i.e. (finger spontaneous photon intensity+filter plate luminous intensity)-filter plate luminous intensity, obtain thumb under different filter plates The luminous intensity of itself, after secondly the light intensity under previous filter plate deducts, the light intensity under a filter plate obtains between two wavelength Finger photon intensity, finally combines different filter plate quantum efficiency in different-waveband, is corrected the numerical value between wave band, Spectral distribution graph is drawn in units of 100nm.
(5) test result.
During can judging body intracellular metabolic on the whole by human body spontaneous luminescent spectrum feature, oxidation is freely The level of base, thus evaluate the health status of body.Physics and the principles of chemistry research of bioluminescence are thought, only sharp when occurring Send out state molecule when ground state transition, just have luminescence phenomenon, in other words, archebiosis light sources is in biomacromolecule new old generation From upper state to the photon of lower state transition radiation, the photon that interior free yl isoreactivity oxygen is discharged, available body during thanking Table superweak luminescence characterizes.Photon emission with metabolism mechanism is thought, intracellular highly active peroxylradicals carry out chemically composited instead During Ying, generate singlet oxygen or excited state carbonyl, when they return to ground state, then give off the photon of different-waveband.In a large number Experimentation show, be embedded in the membrane bound enzyme complex NADPH of cell membrane, mitochondrial membrane, chloroplast membranes, phagosome film etc. Oxidase can be by oxygen (O2) it is converted into ultra-oxygen anion free radical (O2 ·-), O2 ·-Hydrogen peroxide is generated by dismutation reaction (H2O2), H2O2React through Fenton and then change into hydroxyl radical free radical (HO·).There is the HO of higher reproducibility·Thin by oxidation Intracellular includes various types of biomacromolecules of lipid, protein and nucleic acid, ultimately generate triplet excited state carbonyl (3R= O*), substance (1P*) and triple (3P*) excited state pigment and singlet oxygen (1O2).Triplet excited state carbonyl (3R=O*) from upper state To lower state transition produce 350-550nm wave band photon, substance (1P*) and triple (3P*) excited state pigment transition correspondence respectively 550-750nm and 750-1000nm wave band, singlet oxygen transition produces the photon of 634nm and 1270nm wave band.
When body is in morbid state, spectrally can embody at finger spontaneous luminescence.Finger spontaneous luminescence spectrum The peak feature (such as peak intensity, peak position, the quantity at peak) of distribution is possibly as the characteristic index of body metabolic activity, logical Cross test and analyze finger spontaneous luminescence spectral characteristic under different physio-pathological condition, comparing the difference of its spectral distribution feature, I.e. can determine whether the health status of body.
Under health status shown in human body right-hand man finger spectral distribution such as Fig. 3 (a) and Fig. 3 (b).Under morbid state, human body is left Shown in right finger spectral distribution such as Fig. 3 (c) and Fig. 3 (d).From such as Fig. 3 (a) and Fig. 3 (b) it can be seen that ten handss of Healthy People Referring to that spontaneous luminescence strength is apparently higher than other wave band between 495-550nm, prompting health status people ten refers to have relatively at this wave band Strong photon radiation, the i.e. peak value of Healthy People ten finger tip spectral distribution occur between 495-550nm.At this section, every The light intensity numerical value of finger is the most different, shows as left hand and is followed successively by thumb, middle finger, forefinger, little finger of toe and the third finger from high to low, The right hand is followed successively by thumb, middle finger, little finger of toe, forefinger and the third finger.
From Fig. 3 (c) and Fig. 3 (d) it can be seen that refer to that spectral distribution is compared with Healthy People ten, in the right-hand man of cold patients Refer to, nameless and little finger of toe spectrum peak occurs in that Red Shift Phenomena, i.e. spectrum peak moves to 550-610nm from 495-550nm, fixed From the point of view of Liang, i.e. cold patients right-hand man's middle finger, the third finger and little finger of toe light intensity is obvious at the ratio of 550-610nm with 495-550nm Higher than Healthy People (left hand: p=0.007;The right hand: p=0.005).Test result shows, is in the human body of morbid state, and it is raw The distribution of object light sub-radiation spectrum deviates with normal value.
The front in the darkroom of the present invention is provided with dividing plate in being provided with two circular cavities and darkroom, form double darkroom, for real Now right-hand man's bio-photon is detected simultaneously;And the present invention uses high sensitivity and the photomultiplier transit without additional refrigeration Pipe detects the bio-photon of each finger of hands, improves the measuring accuracy of whole device and makes simple to operate, this The bright state that can indicate health intuitively and there is quick, sensitive, reliable and lossless to human finger advantage.
If the present invention uses the photomultiplier tube of the surface being vertically mounted on darkroom and is arranged on filter plate wheel The filter plate of dry group different-waveband, detects the luminous intensity under arbitrary group of filter plate of the finger in darkroom and arbitrary group of filtering The luminous intensity of sheet self, and the luminous intensity of the luminous intensity of the finger under same group of filter plate with filter plate self is made Difference, obtains finger self-luminous intensity under specific band, and then draws out finger spectral distribution graph exactly.
Although the detailed description of the invention of the present invention is described by the above-mentioned accompanying drawing that combines, but not the present invention is protected model The restriction enclosed, one of ordinary skill in the art should be understood that on the basis of technical scheme, and those skilled in the art are not Need to pay various amendments or deformation that creative work can make still within protection scope of the present invention.

Claims (9)

1. a finger biometric photon radiation spectral distribution graph drawing apparatus, it is characterised in that including darkroom, described darkroom is just Face is provided with the hole stretching into staff, and the surface in described darkroom is vertically installed with photomultiplier tube, described darkroom and photoelectricity times Increase and between pipe, be also equipped with filter plate wheel, described filter plate wheel carries the filter plate of some groups of different-wavebands;
Filter plate is for when there being finger in darkroom, the bio-photon of generation spontaneous to the finger in darkroom is filtered, and will Filtered bio-photon is sent to photomultiplier tube and carries out being converted into bioelectrical signals, and the bioelectrical signals after conversion is by photoelectricity Multiplier tube is sent to photon counter, obtains finger luminous intensity under arbitrary group of filter plate;
Described filter plate is additionally operable to when in darkroom without finger, and self-luminous produces optical signal, and optical signal self-luminous produced It is sent to photon counter by photomultiplier tube, obtains the luminous intensity of arbitrary group of filter plate self;
Described photon counter is also connected with central processing unit, and described central processing unit is used for receiving finger at arbitrary group of filter plate Under luminous intensity and the luminous intensity of arbitrary group of filter plate self, and by the luminous intensity of the finger under same group of filter plate with The luminous intensity of filter plate self is poor, obtains finger self-luminous intensity under specific band, and then draws out finger spectrum Scattergram.
2. a kind of finger biometric photon radiation spectral distribution graph drawing apparatus as claimed in claim 1, it is characterised in that described Hole outer is fixed with black rubber set, for preventing the entrance of ambient.
3. a kind of finger biometric photon radiation spectral distribution graph drawing apparatus as claimed in claim 1, it is characterised in that described Filter plate wheel is the filter plate wheel of Electronic control.
4. a kind of finger biometric photon radiation spectral distribution graph drawing apparatus as claimed in claim 1, it is characterised in that described Finger biometric photon radiation spectral distribution graph drawing apparatus also includes high voltage power supply, and described high voltage power supply is used for as photomultiplier tube Power supply is provided.
5. a kind of finger biometric photon radiation spectral distribution graph drawing apparatus as claimed in claim 1, it is characterised in that described The front in darkroom is provided with dividing plate in being provided with two circular cavities and darkroom, examines right-hand man's bio-photon for realization simultaneously Survey.
6. a kind of finger biometric photon radiation spectral distribution graph drawing apparatus as claimed in claim 3, it is characterised in that described Central processing unit is also connected with display screen.
7. the work side of the finger biometric photon radiation spectral distribution graph drawing apparatus as described in claim 1-6 is arbitrary Method, it is characterised in that including:
Stretching in darkroom by hands by hole, the bio-photon of each finger of opponent is tested:
In test process, the bio-photon of the spontaneous generation of finger in darkroom, after arbitrary group of filter plate filtering, is sent to Photomultiplier tube is also converted into bioelectrical signals, and the bioelectrical signals after conversion is sent to photon counter by photomultiplier tube, The bioelectrical signals received is processed by photon counter, obtains finger luminous intensity under arbitrary group of filter plate;
When in darkroom without finger, the optical signals photomultiplier tube of arbitrary group of filter plate self-luminous generation is sent to photon counting After device, obtain the luminous intensity of arbitrary group of filter plate self;
By poor to the luminous intensity of the finger under same group of filter plate and the luminous intensity of filter plate self, obtain finger specific Self-luminous intensity under wave band, and then draw out finger spectral distribution graph.
8. the method for work of finger biometric photon radiation spectral distribution graph drawing apparatus as claimed in claim 7, its feature exists In, after obtaining finger self-luminous intensity under specific band, also include according to different filter plate amounts in different-waveband Finger self-luminous intensity under specific band is corrected by sub-efficiency.
9. the method for work of finger biometric photon radiation spectral distribution graph drawing apparatus as claimed in claim 7, its feature exists In, before the method also includes by hole, hands is stretched into darkroom, temperature regulation is controlled to 20 DEG C and ambient humidity Between 40%-50%.
CN201610528225.3A 2016-07-05 2016-07-05 Finger bio-photon emission spectral distribution graph drawing device and method thereof Pending CN106037669A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610528225.3A CN106037669A (en) 2016-07-05 2016-07-05 Finger bio-photon emission spectral distribution graph drawing device and method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610528225.3A CN106037669A (en) 2016-07-05 2016-07-05 Finger bio-photon emission spectral distribution graph drawing device and method thereof

Publications (1)

Publication Number Publication Date
CN106037669A true CN106037669A (en) 2016-10-26

Family

ID=57201123

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610528225.3A Pending CN106037669A (en) 2016-07-05 2016-07-05 Finger bio-photon emission spectral distribution graph drawing device and method thereof

Country Status (1)

Country Link
CN (1) CN106037669A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111000531A (en) * 2019-12-26 2020-04-14 新绎健康科技有限公司 Method and device for evaluating body changes before and after exercise
CN118464878A (en) * 2024-05-11 2024-08-09 山东第一医科大学(山东省医学科学院) A rapid detection device and method for bioluminescence intensity of traditional Chinese medicine decoction

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507562A (en) * 1980-10-17 1985-03-26 Jean Gasiot Methods for rapidly stimulating luminescent phosphors and recovering information therefrom
WO2010146134A2 (en) * 2009-06-17 2010-12-23 W.O.M World Of Medicine Ag Device and method for multi-photon fluorescence microscopy for obtaining information from biological tissue
CN102048523A (en) * 2010-11-19 2011-05-11 山东省医药生物技术研究中心 Device and method for quantitative measurement of symptom in traditional Chinese medicine by use of human bio-photon radiation
CN203688443U (en) * 2013-12-23 2014-07-02 西安理工大学 Biological ultraweak photon radiation spectroscopic detector
EP2813174A1 (en) * 2013-06-11 2014-12-17 Spiess Media Systems Asc, Corp. Wearable modular sensor system
US20160007855A1 (en) * 2014-07-09 2016-01-14 National Taiwan University Image detection system for diagnosing physiologic status of organ having fluorescent matter

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507562A (en) * 1980-10-17 1985-03-26 Jean Gasiot Methods for rapidly stimulating luminescent phosphors and recovering information therefrom
WO2010146134A2 (en) * 2009-06-17 2010-12-23 W.O.M World Of Medicine Ag Device and method for multi-photon fluorescence microscopy for obtaining information from biological tissue
CN102048523A (en) * 2010-11-19 2011-05-11 山东省医药生物技术研究中心 Device and method for quantitative measurement of symptom in traditional Chinese medicine by use of human bio-photon radiation
EP2813174A1 (en) * 2013-06-11 2014-12-17 Spiess Media Systems Asc, Corp. Wearable modular sensor system
CN203688443U (en) * 2013-12-23 2014-07-02 西安理工大学 Biological ultraweak photon radiation spectroscopic detector
US20160007855A1 (en) * 2014-07-09 2016-01-14 National Taiwan University Image detection system for diagnosing physiologic status of organ having fluorescent matter

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
YANG MEINA, PANG JIANG XIANG, ET AL: "Spectral discrimination between healthy people and cold patients using spontaneous photon emission", 《BIOMEDICAL OPTICS EXPRESS》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111000531A (en) * 2019-12-26 2020-04-14 新绎健康科技有限公司 Method and device for evaluating body changes before and after exercise
CN118464878A (en) * 2024-05-11 2024-08-09 山东第一医科大学(山东省医学科学院) A rapid detection device and method for bioluminescence intensity of traditional Chinese medicine decoction
CN118464878B (en) * 2024-05-11 2025-02-18 山东第一医科大学(山东省医学科学院) Quick detection equipment and method for bioluminescence intensity of traditional Chinese medicine decoction

Similar Documents

Publication Publication Date Title
US11668844B2 (en) System and method for the detection of gamma radiation from a radioactive analyte
CN1253127C (en) Examination of breast tissue using time-resolved spectroscopy
EP2813866A1 (en) Photodetector and computed tomography apparatus
US20100126882A1 (en) Electrochemical biosensor measuring system
Quickenden et al. Weak luminescence from the yeast Saccharomyces cerevisiae and the existence of mitogenetic radiation
ES2735283T3 (en) Procedure for determining the radiation dose deposited in a scintillator by an ionizing radiation and associated device
CN109864747A (en) Multi-mode analyte sensor optoelectronic interface
Inaba et al. Development of an ultra-high sensitive photon counting system and its application to biomedical measurements
CN106037669A (en) Finger bio-photon emission spectral distribution graph drawing device and method thereof
CN105353398B (en) A kind of on-line measurement system and method for radon and thorium emanation and its daughter concentration
JP2010133879A (en) Radiation measuring apparatus
CN111413726B (en) Radon measuring instrument and calibration method thereof
CN205994487U (en) A kind of finger biometric photon radiation spectral distribution graph drawing apparatus
JP4399971B2 (en) ECT device
CN111938664B (en) Wearable intelligent noninvasive blood glucose monitoring device based on microfluidic technology
US10258297B2 (en) Medical Diagnostic-imaging apparatus
CN110954935B (en) A Radon Measurement Device Based on Ionization Chamber and Semiconductor Detector
Morozov et al. Adaptive algorithms of position and energy reconstruction in Anger-camera type detectors: experimental data processing in ANTS
WO2006117475A1 (en) Gamma camera for localizing sentinel nodes
CN212181043U (en) Control circuit of emanometer
Nodari et al. Radon fast detection and environmental monitoring with a portable wireless system
CN111610553A (en) A scintillation hand-held spectrometer based on sql digitization method and its spectrum forming method
CN106236022B (en) System for early screening breast cancer by using biological photon radiation of organism
CN102435325A (en) Single photon counter for identifying non-illumination thermal electron noise pulse
KR20170027220A (en) Apparatus and method for measuring ripening degree using light-emitting microorganisms

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20161026

RJ01 Rejection of invention patent application after publication