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CN105983178A - Pace-making generation device - Google Patents

Pace-making generation device Download PDF

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Publication number
CN105983178A
CN105983178A CN201510054434.4A CN201510054434A CN105983178A CN 105983178 A CN105983178 A CN 105983178A CN 201510054434 A CN201510054434 A CN 201510054434A CN 105983178 A CN105983178 A CN 105983178A
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current
signal
resistance
voltage
input
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CN201510054434.4A
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CN105983178B (en
Inventor
王晶
尹鹏
易明生
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Shenzhen Comen Medical Instruments Co Ltd
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Shenzhen Comen Medical Instruments Co Ltd
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Abstract

The present invention relates to a pace-making generation device. The device comprises: an impedance detection unit configured to detect the impedance value of a patient to output the impedance value of the patient; a constant flow source configured to connect with the patient and output the pace-making current to the patient; a microprocessor configured to output simulation voltage to the constant flow source according to a target pace-making current signal so as to control the constant flow source to output the pace-making current and configured to receive the resistance value and determine a target voltage value according to the resistance value and the target pace-making current signal and then output regulation signals; and boost unit configured to receive the regulation signals, regulate the pace-making voltage according to the regulation signals and connect with the patient to output the pace-making voltage to the patient. The pace-making generation device can effectively ensure the safety of the current and the voltage loaded on a patient's body so as to ensure the safety of the patient.

Description

Pacemaking generation device
Technical field
The present invention relates to technical field of medical instruments, particularly relate to pacemaking generation device.
Background technology
Need that patient is carried out external noinvasive pace-making in clinical emergency aid and treatment occasion and give treatment to effect timely to obtain Really.Defibrillation monitor has noinvasive pacing function, it is possible to produces some strength and the electric pulse of width, and leads to Cross electrode and be released to heart, stimulate cardiac muscle such that it is able to the bradycardia after defibrillation is treated.Body Outer human body breast resistance scope more internal impedance width, general range is from 20 ohm~200 ohm.In view of each Planting difference and the contact impedance of skin of human body, the paced impedance ranges that defibrillation monitor sets is generally 20 ohm~750 ohm, and clinical effective stimulus pulse current excursion 5mA~200mA.Therefore act on Voltage range in human body is 0.1V~150V.Owing to electric pulse directly acts on human body cardiac stimulus, too high Voltage and excessive electric current patient will be damaged, therefore need to pace-making during to acting on human body Pace-making voltage and current carry out real-time monitoring, when occur overtension or electric current excessive time stop pace-making Output, protects patient.
Tradition pacing system uses the mode of hardware protection to the voltage protection of pacing circuitry, and protection point sets substantially It is set to the maximum operating voltage of pacemaker.And when the impedance of patient is relatively low, due to pace-making protection point voltage Set too high, after being loaded into human body, still patient can be damaged.The electric current of traditional pacing system controls It is by sampling resistor, pacemaker current to be sampled, sends into microprocessor after ADC digital and carry out judging electricity Stream is the most normal, if current anomaly, then cuts off pace-making loop;The method uses software to realize.And use Electric current is controlled to have the disadvantage that (1) software sampling by software mode, has certain time delay;(2) when soft When part sampling makes mistakes, human body can be damaged by too high pacemaker current.
Summary of the invention
Based on this, it is necessary to for the problems referred to above, it is provided that the pace-making of a kind of safety that can effectively ensure that patient Generating means.
A kind of pacemaking generation device, including: impedance detection unit, for detecting the resistance value of patient and exporting; Constant-current source, for being connected with patient and exporting pacemaker current to described patient;Microprocessor, respectively with described Impedance detection unit, described constant-current source connect;Described microprocessor is for defeated according to target pacemaker current signal Go out analog voltage give described constant-current source, thus control described constant-current source output pacemaker current;Described microprocessor It is additionally operable to receive described resistance value, and determines target according to described resistance value and described target pacemaker current signal Output regulation signal after magnitude of voltage;And boosting unit, it is connected with described microprocessor, is used for receiving described Regulation signal also adjusts pace-making voltage according to described regulation signal;Described boosting unit is additionally operable to be connected with patient Pace-making voltage is exported to described patient.
Wherein in an embodiment, also include Overvoltage protecting unit;Described Overvoltage protecting unit is connected to institute State between boosting unit and described microprocessor;Described Overvoltage protecting unit is for exporting described boosting unit Pace-making voltage carry out sampling and when there is overvoltage in sampled voltage output overvoltage signal to described boosting unit and Described microprocessor;Described Overvoltage protecting unit includes first order overvoltage crowbar and second level overvoltage protection Circuit;Described first order overvoltage crowbar is for protecting voltage signal ratio by described sampled voltage with the first order Relatively and at described sampled voltage it is more than output overvoltage signal when the described first order protects voltage signal;Described second Level overvoltage crowbar is for comparing described sampled voltage and in described sampling with second level protection voltage signal Voltage is more than output overvoltage signal during the protection voltage signal of the described second level;Described first order protection voltage signal Voltage signal is protected less than the described second level.
Wherein in an embodiment, described first order protection voltage signal is adjustable voltage signal, by described Microprocessor is set according to described target voltage values;Described second level protection voltage signal is fixed voltage Signal, determines according to the maximum operating voltage of described pacemaking generation device.
Wherein in an embodiment, described first order overvoltage crowbar includes the first comparator, the first electricity Resistance and the first diode;The input of described first comparator is respectively sampled voltage input and the first order is protected Protect voltage signal inputs;The outfan of described first comparator respectively with described first resistance, described first Diode connects;Described first resistance is also connected with power input;The negative electrode of described first diode also with Described microprocessor, described boosting unit connect;Described second level overvoltage crowbar include the second comparator, Second resistance, the 3rd resistance, the 4th resistance and the second diode;The input of described second comparator divides Do not protect voltage signal inputs for sampled voltage input and the second level;Described second level protection voltage signal Formed by described second resistance and described 3rd electric resistance partial pressure;The outfan of described second comparator respectively with institute State the 4th resistance, the second diode connects;Described 4th resistance is also connected with described power input;Described The negative electrode of the second diode also negative electrode with described first diode is connected.
Wherein in an embodiment, also include over-current protecting unit and current sampling unit;Described electric current is adopted Sample unit is connected with described constant-current source, samples for the pacemaker current exporting described constant-current source and exports Sample rate current;Described over-current protecting unit respectively with described current sampling unit, described constant-current source and described Microprocessor connects;Described over-current protecting unit includes first order current foldback circuit and second level overcurrent protection Circuit;Described first order current foldback circuit is for by described sample rate current and first order protective current signal ratio Relatively and described sample rate current more than the described first order protective current signal time output overcurrent signal;Described second Level current foldback circuit is for comparing described sample rate current and in described sampling with second level protective current signal Electric current is more than output overcurrent signal during described second level protective current signal;Described first order protective current signal Less than described second level protective current signal.
Wherein in an embodiment, described first order protective current signal is adjustable current signal, by described Microprocessor is set according to described target pacemaker current signal;Described second level protective current signal is solid Determine current signal, determine according to the maximum operating currenbt of described pacemaking generation device.
Wherein in an embodiment, described first order current foldback circuit includes the 3rd comparator, the 5th electricity Resistance, the 3rd diode;The input of described 3rd comparator is respectively sample rate current input and the first order is protected Protect current signal input;The outfan of described 3rd comparator respectively with described 5th resistance, the described 3rd Diode connects;Described 5th resistance is also connected with power input;The negative electrode of described 3rd diode also with Microprocessor, described constant-current source connect;Described second level current foldback circuit include the 4th comparator, the 6th Resistance, the 7th resistance, the 8th resistance and the 4th diode;The input of described 4th comparator is respectively Sample rate current input and second level protective current signal input part;Second level protective current signal input part is even It is connected between described 6th resistance and described 7th resistance;Described 6th resistance is also connected with power input, The other end ground connection of described 7th resistance;The outfan of described 4th comparator the most respectively with described 8th resistance, Described 4th diode connects;Described 8th resistance is also connected with described power input;Described four or two pole The negative electrode of pipe also negative electrode with described 3rd diode is connected.
Wherein in an embodiment, described first order current foldback circuit also includes the first latching circuit;Institute State the first latching circuit and be connected to outfan and the sample rate current input of described 3rd comparator;Described second Level current foldback circuit also includes the second latching circuit;Described second latching circuit is connected to the described 4th and compares The outfan of device and sample rate current input.
Wherein in an embodiment, described over-current protecting unit also included stream reset circuit;Described mistake is flowed Reset circuit includes the first audion and the 9th resistance;The base stage of described first audion and described microprocessor Connect, for receiving the stream reset signal excessively of described microprocessor output;The colelctor electrode of described first audion It is connected with sample rate current input, the sample rate current input of the 4th comparator of described 3rd comparator respectively; Ground connection after emitter stage described 9th resistance of series connection of described first audion.
Wherein in an embodiment, described current sampling unit include operational amplifier, the first sampled point and Second sampled point;Described first sampled point and described second sampled point lay respectively at the not coordination of described constant-current source Put;Described first sampled point, described second sampled point respectively with the first input end of described operational amplifier, Second input connects;Described second sampled point also sample rate current input with described 3rd comparator is connected; The outfan of described operational amplifier is connected with the sample rate current input of described 4th comparator.
Above-mentioned pacemaking generation device, being applied to the pacemaker current with patient can be by microprocessor according to target Pacemaker current signal exports corresponding analog voltage thus controls constant-current source output target pacemaker current;Pace-making electricity Pressure then can be calculated applicable patient by microprocessor according to resistance value and the target pacemaker current signal of patient Pace-making voltage, thus the pace-making voltage being applied to patient is adjusted by output corresponding regulation signal, Can effectively ensure that and be loaded into the electric current with patient and voltage security, thus ensure that the safety of patient.
Accompanying drawing explanation
Fig. 1 is the structured flowchart of the pacemaking generation device in an embodiment;
Fig. 2 is the structured flowchart of the pacemaking generation device in another embodiment;
Fig. 3 is the circuit theory diagrams of the constant-current source in the pacemaking generation device shown in Fig. 2 and current sampling unit;
Fig. 4 is the circuit theory diagrams of the over-current protecting unit in the pacemaking generation device shown in Fig. 2;
Fig. 5 is the circuit theory diagrams of the Overvoltage protecting unit in the pacemaking generation device shown in Fig. 2.
Detailed description of the invention
In order to make the purpose of the present invention, technical scheme and advantage clearer, below in conjunction with accompanying drawing and reality Execute example, the present invention is further elaborated.Only should be appreciated that specific embodiment described herein Only in order to explain the present invention, it is not intended to limit the present invention.
Fig. 1 is the structured flowchart of the pacemaking generation device in an embodiment.A kind of pacemaking generation device, including Impedance detection unit 110, constant-current source 120, microprocessor 130 and boosting unit 140.Wherein, impedance Detector unit 110 is connected with microprocessor 130, microprocessor 130 the most respectively with boosting unit 140 and Constant-current source 120 connects.
Impedance detection unit 110 is connected with patient by electrode, thus detects the resistance value of patient also Output is to microprocessor 130.Constant-current source 120 is connected with patient also by electrode, for exporting pace-making to patient Electric current.Microprocessor 130 is used for receiving target pacemaker current signal, and according to this target pacemaker current signal Export correspondingly analog voltage, to constant-current source 120, thus to control constant-current source 120 and export corresponding pacemaker current, Guarantee the electric current safety being loaded on patient body.Microprocessor 130 is additionally operable to receive impedance detection unit 110 The resistance value of output, and determine according to this resistance value and target pacemaker current signal and export after target voltage values Regulation signal is to boosting unit 140.Pace-making voltage is carried out by boosting unit 140 according to the regulation signal received Adjust, thus export target pace-making voltage by electrode to patient, it is ensured that the voltage being loaded on patient body Safety.
Above-mentioned pacemaking generation device, being applied to the pacemaker current with patient can be by microprocessor 130 basis Target pacemaker current signal exports corresponding analog voltage thus controls constant-current source 120 and export target pacemaker current; Pace-making voltage then can be calculated according to resistance value and the target pacemaker current signal of patient by microprocessor 130 Go out the pace-making voltage of applicable patient, thus the pace-making electricity that output corresponding regulation signal is to being applied to patient It is pressed into Row sum-equal matrix, it is possible to be effectively ensured and be loaded into the electric current with patient and voltage security, thus ensure that The safety of patient.
Fig. 2 is the structured flowchart of the pacemaking generation device in another embodiment.A kind of pacemaking generation device includes resistance Anti-detector unit 210, constant-current source 220, current sampling unit 230, microprocessor 240, over-current protecting unit 250, boosting unit 260 and Overvoltage protecting unit 270.
Impedance detection unit 210 is connected with patient by electrode, and detects the resistance value of patient.Specifically Ground, the voltage and current flowing through patient can be detected and obtain according to detection by impedance detection unit 210 Current value and magnitude of voltage are calculated the resistance value of patient.
Constant-current source 220 is respectively with microprocessor 240, current sampling unit 230 and over-current protecting unit 250 even Connect.Microprocessor 240 is used for receiving target pacemaker current signal, and target pacemaker current signal can be according to patient Concrete condition be set.Microprocessor 240 calculates constant-current source according to the target pacemaker current signal received 220 produce the magnitude of voltage required for target pacemaker current.Microprocessor 240 is according to calculated magnitude of voltage control DAC processed (digital analog converter) output analog voltage DAC_CURRENT is to constant-current source 220.Constant-current source The pacemaker current of output is adjusted under the control of analog voltage DAC_CURRENT by 220, thus reaches The purpose of regulation body current.Current sampling unit 230 respectively with constant-current source 220, microprocessor 240 and mistake Stream protected location 250 connects.Current sampling unit 230 is for carrying out the pacemaker current in constant-current source 220 loop Sampling, and sample rate current is exported to over-current protecting unit 250.In the present embodiment, current sampling unit 230 Also can export to microprocessor 240 after sample rate current being converted to digital current signal by analog-digital converter.
Fig. 3 is constant-current source 220 and the circuit theory diagrams of current sampling unit 230.Constant-current source 220 includes that computing is put Big device U5, diode Q2, metal-oxide-semiconductor Q3 and resistance R10~R13.Wherein, the of operational amplifier U5 It is connected with microprocessor 240 after one input series resistance R10, for receiving the simulation of microprocessor 240 output Voltage DAC_CURRENT.It is connected to metal-oxide-semiconductor Q3 after outfan series resistance R13 of operational amplifier U5 Grid.The grid of metal-oxide-semiconductor Q3 is also attached to the colelctor electrode of audion Q2.The base stage of audion Q2 flows with crossing Protected location 270 connects, for receiving the over-current signal of its output.The grounded emitter of audion Q2.MOS Ground connection after drain series resistance R11 of pipe Q3 and resistance R12.The source electrode of metal-oxide-semiconductor Q3 passes through electrode and patient Connect.Current sampling unit 230 includes operational amplifier U6, the first sampled point P1 and the second sampled point P2.The One sampled point P1 and the second sampled point P2 lays respectively at the diverse location in constant-current source 220, such that it is able to avoid electricity There is affecting during single failure the normal work of current sample in road.Specifically, the second sampled point P2 is arranged at MOS The drain electrode of pipe Q2, the first sampled point P1 is then arranged between resistance R11 and resistance R12.First sampled point P1 It is connected with first input end and second input of operational amplifier U6 respectively with the second sampled point P2.First adopts Sampling point P1 also crosses stream as the first current sampling signal outfan and the first order in over-current protecting unit 250 and protects Sample rate current input in protection circuit connects.The outfan of operational amplifier U6 then with over-current protecting unit 250 In second level current foldback circuit in sample rate current input connect.
Over-current protecting unit 250 is for according to the sample rate current of current sampling unit 230 output to pacemaker current being The no overcurrent condition that exists is monitored in real time, once overcurrent condition be detected, output overcurrent signal is to constant-current source 220, control the audion Q2 conducting in constant-current source 220, so that metal-oxide-semiconductor Q3 cut-off, quickly and effectively Turn off the output of pacemaker current, it is ensured that apply electric current safety on a patient body.Meanwhile, overcurrent protection list Over-current signal also can be exported to microprocessor 240 by unit 250.After microprocessor 240 receives over-current signal, control DAC processed stops output analog voltage to constant-current source 220 so that constant-current source 220 quits work, and is further ensured that Electric current safety.
In the present embodiment, over-current protecting unit 250 includes that first order current foldback circuit, the second level are crossed stream and protected Protection circuit and excessively stream reset circuit, as shown in Figure 4.Wherein, first order current foldback circuit includes the 3rd ratio Relatively device U3, the 3rd diode D3, the 5th resistance R5 and the first latching circuit.The input of the 3rd comparator U3 End is respectively first order protective current signal input part and sample rate current input.Wherein, first order protection electricity Stream signal input part is connected with microprocessor 240, for receiving the first order protection electricity of microprocessor 240 output Stream signal DA_SAMPLE.Sample rate current input then with the first sampled point P1 in current sampling unit 230 Connect, for receiving the first current sampling signal.In the present embodiment, first order protective current signal DA_SAMPLE is set according to target pacemaker current signal by microprocessor 240, for adjustable electric Stream signal.Owing to different patients can set different target pacemaker current signals, therefore first order protection Arranging of current signal can adapt with the concrete condition of patient, so that it is guaranteed that apply on a patient body Electric current safety.In the present embodiment, first order protective current signal DA_SAMPLE is set to target pace-making electricity 1.1 times of stream signal.3rd comparator U3 outfan series connection the 3rd diode D3 after respectively with microprocessor 240 and constant-current source 220 connect.3rd comparator U3 sample rate current more than the first order protective current signal time, Meeting output overcurrent signal is to microprocessor 240 and constant-current source 220.In the present embodiment, over-current signal is high electricity Ordinary mail number.First latching circuit includes diode D5.The anode of diode D5 is connected to the 3rd comparator U3's Input, negative electrode is then connected to the sample rate current input of the 3rd comparator U3.First latching circuit can be real Existing auto-lock function, has i.e. served as flowing out now, and the output signal of the 3rd comparator U3 can be fed back by latching circuit To input, so that input obtains constant input signal, to maintain the output of the 3rd comparator U3. And without the comparator of auto-lock function, due to sample rate current reduce cause the 3rd comparator U3 output switching, When microprocessor breaks down and do not stops DAC output pacemaker current, pacemaker current will continue at human body On, damage to patient.
Second level current foldback circuit include the 4th comparator U4, the 6th resistance R6, the 7th resistance R7, the 8th Resistance R8 and the 4th diode D4, also includes second from lock unit.The input of the 4th comparator U4 is respectively For second level protective current signal input part and sample rate current input.Wherein, second level protective current signal More than first order protective current signal.Second level protective current signal is fixed current signal, and it is according to pace-making The maximum operating currenbt of generating means is set.In the present embodiment, protective current signal in the second level is arranged 1.2 times of the maximum operating currenbt of pacemaking generation device.Second level protective current signal input part is connected to the 6th Between resistance R6 and the 7th resistance R7.6th resistance R6 is also connected with power input VCC, the 7th resistance R7 Other end ground connection.Sample rate current input then with the output of the operational amplifier U6 in current sampling unit 230 End connects, for receiving the second current sampling signal of its output.The outfan series connection the of the 4th comparator U4 It is connected with microprocessor 240 and constant-current source 220 after four diode D4.Going back of the outfan of the 4th comparator U4 Connect and be connected with power input VCC after the 8th resistance R8.4th comparator U4 is more than second at sample rate current Output overcurrent signal during level protective current signal.Second latching circuit includes diode D6.The sun of diode D6 Pole is connected to the outfan of the 4th comparator U4, and negative electrode is connected to the sample rate current input of the 4th comparator, For stablizing the output of the 4th comparator.
In the present embodiment, current sampling unit 230 is also connected with microprocessor 240, for by sample rate current Output is to microprocessor 240.Microprocessor 240 is set with overcurrent protection threshold value, this overcurrent protection threshold value with Second level protective current signal is identical.Microprocessor 240 can be by internal intervalometer timing receipt sampling electricity Stream, when the sample rate current detected is more than overcurrent protection threshold value, controls DAC and stops output analog voltage, So that constant-current source 220 quits work.
Cross stream reset circuit and include the first audion Q1, the 9th resistance R9 and diode D7, D8.Wherein, The base stage of the first audion Q1 is connected with microprocessor 240, flows again for receiving crossing of microprocessor 240 output Position signal.The colelctor electrode of the first audion Q1 negative electrode with diode D7, diode D8 respectively is connected.Two poles The anode of pipe D7 is connected to the sample rate current input of the 3rd comparator U3, and the anode of diode D8 is then connected to The sample rate current input of the 4th comparator U4.Emitter stage series connection the 9th resistance R9 of the first audion Q1 is followed by Ground.In the present embodiment, owing to current foldback circuit being provided with latching circuit, therefore crossing stream generation Output overcurrent signal stablized by comparator always afterwards.After having served as stream releasing, microprocessor 240 can be to crossing stream Reset circuit output overcurrent reset signal.Crossing stream reset signal is high level signal so that the first audion Q3 Conducting, drags down the level of the sample rate current input of the 3rd comparator U3 and the 4th comparator U4, the 3rd ratio Relatively device U3 and the 4th comparator U4 stops output overcurrent signal, it is achieved the reset to comparator.
By arranging two-stage current protecting circuit, second level over-current protection point is higher than first order over-current protection point. Therefore, when there is stream, first order protection can first be triggered, if first order shielding failure, it is also possible to would touch Send out second level overcurrent protection such that it is able to the electric current safety that loads on a patient body is effectively ensured.Electric current is protected Protection circuit is capable of auto-lock function, and stream once occurred, and is exported by locking over-current signal, turns off pace-making electricity The output of stream.Further, pacemaker current can also be monitored by microprocessor 240 according to sample rate current.Therefore, When over-current protecting unit 250 lost efficacy, additionally it is possible to carry out overcurrent protection by microprocessor 240, thus realize To the three-level protective crossing stream, it is ensured that be loaded into the electric current safety of human body.Overcurrent protection due to microprocessor 240 Having time delay, therefore its overcurrent protection is necessarily delayed in second level current foldback circuit.
Microprocessor 240 is additionally operable to receive the resistance value of impedance detection unit 210 output, and according to resistance value and Target pacemaker current signal calculates the target voltage values being suitable for patient.Microprocessor 240 is according to the target calculated Magnitude of voltage output corresponding regulation signal is to boosting unit 260.Boosting unit 260 according to this regulation signal to rise Voltage of fighting is adjusted, thus reaches to change the purpose of the pace-making voltage of output.Boosting unit 260 includes boosting Changer and digital regulation resistance.Digital regulation resistance is connected between the feedback end of booster converter and earth terminal. Digital regulation resistance also with the connection of microprocessor 240, for adjusting resistance value according to regulation signal, thus real The now adjustment to pace-making voltage.
Overvoltage protecting unit 270 is connected between boosting unit 260 and microprocessor 240.Overvoltage protecting unit 270, for sampling the pace-making voltage of boosting unit 260 output, export when sampled voltage exists overvoltage The enable signal of booster converter, to boosting unit 260, is directly dragged down, forbids booster converter by overvoltage signal Enable, turn off the output of pace-making voltage quickly and effectively.Overvoltage signal also can be exported by Overvoltage protecting unit 270 To microprocessor 240.Microprocessor 240 is after receiving overvoltage signal, and output is forbidden enabling signal to boosting Unit, turns off the output of pace-making voltage.
Overvoltage protecting unit 270 includes first order overvoltage crowbar and second level overvoltage crowbar, such as Fig. 5 Shown in.First order overvoltage crowbar includes the first comparator U1, the first resistance R1 and the first diode D1. Wherein, the input of the first comparator U1 is sampled voltage input and first order protection voltage signal inputs. First order protection voltage signal inputs is connected with microprocessor 240, for receiving microprocessor 240 output First order protection voltage signal DA.In the present embodiment, first order protection voltage signal DA is adjustable voltage letter Number, microprocessor 240 it is determined according to target pace-making magnitude of voltage, so that first order protection voltage letter Number DA matches with patient.In the present embodiment, first order protection voltage signal DA is set as target pace-making electricity 1.1 times of pressure.The outfan of the first comparator U1 connect after the first diode D1 respectively with microprocessor 240 with And boosting unit 260 connects.The outfan of the first comparator U1 also connect after the first resistance R1 with power input VCC connects.When sampled voltage is more than first order protection voltage signal DA, the first comparator U1 output overvoltage Signal.
Second level overvoltage crowbar include the second comparator U2, the second resistance R2, the 3rd resistance R3, the 4th Resistance R4 and the second diode D2.Wherein, the input of the second comparator U2 is sampled voltage input and Second class protection voltage signal inputs.Second level protection voltage signal inputs is connected to the second resistance R2 and the Between three resistance R3.Second resistance R2 is also connected with power input, the other end ground connection of the 3rd resistance R3. In the present embodiment, protection voltage signal in the second level protects voltage signal DA more than the first order.The second level is protected Voltage signal is fixed voltage signal, and it can be set according to the maximum operating voltage of pacemaking generation device. In the present embodiment, the second level protection voltage signal be set to pacemaking generation device maximum operating voltage 1.15 Times.The outfan of the second comparator U2 connect after the second diode D2 respectively with microprocessor 240 and boosting Unit 260 connects.The outfan of the second comparator U2 also connect after the 4th resistance R4 with power input VCC Connect.When sampled voltage is more than second level protection voltage signal, the second comparator U2 output overvoltage signal.
Overvoltage protecting unit 270 uses the mode that twin-stage is protected, and has taken into full account single failure situation so that Single failure situation remains to effectively close the output of pace-making voltage, improves the safety and reliability of system, Ensure that the voltage security being applied to patient.And first order protection voltage signal can be according to target Magnitude of voltage (i.e. target pacemaker current signal and patent impedance) carries out the adjustment of over-voltage protection point, so that Obtain overvoltage protection and can adapt to different patients.
Above-mentioned pacemaking generation device, applies pacemaker current on a patient body and pace-making voltage can basis The resistance value of patient self is set, thus avoid pacing overtension, pacemaker current is excessive makes patient Become infringement.Further, above-mentioned pacemaking generation device is additionally provided with over-current protecting unit 250 and the twin-stage of twin-stage protection The Overvoltage protecting unit 270 of protection, it is possible to ensure to apply voltage on a patient body and electric current safety.
Above-mentioned pacemaking generation device also includes DC-DC isolated location, be used for pace voltage output loop with Isolation between input source, plays the purpose of pace-making output loop and network source isolation.Boosting unit 260 is DC-DC boosting unit.
Each technical characteristic of embodiment described above can combine arbitrarily, for making description succinct, the most right The all possible combination of each technical characteristic in above-described embodiment is all described, but, if these skills There is not contradiction in the combination of art feature, is all considered to be the scope that this specification is recorded.
Embodiment described above only have expressed the several embodiments of the present invention, and it describes more concrete and detailed, But can not therefore be construed as limiting the scope of the patent.It should be pointed out that, for this area For those of ordinary skill, without departing from the inventive concept of the premise, it is also possible to make some deformation and change Entering, these broadly fall into protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be with appended power Profit requires to be as the criterion.

Claims (10)

1. a pacemaking generation device, it is characterised in that including:
Impedance detection unit, for detecting the resistance value of patient and exporting;
Constant-current source, for being connected with patient and exporting pacemaker current to described patient;
Microprocessor, is connected with described impedance detection unit, described constant-current source respectively;Described microprocessor is used In giving described constant-current source according to target pacemaker current signal output analog voltage, thus it is defeated to control described constant-current source Go out pacemaker current;Described microprocessor is additionally operable to receive described resistance value, and according to described resistance value and described Target pacemaker current signal determines output regulation signal after target voltage values;And
Boosting unit, is connected with described microprocessor, is used for receiving described regulation signal and according to described regulation Signal adjusts pace-making voltage;Described boosting unit is additionally operable to be connected with patient export pace-making voltage to described patient.
Pacemaking generation device the most according to claim 1, it is characterised in that also include overvoltage protection list Unit;Described Overvoltage protecting unit is connected between described boosting unit and described microprocessor;Described overvoltage is protected Protect unit to sample and when sampled voltage exists overvoltage for the pace-making voltage that described boosting unit is exported Output overvoltage signal gives described boosting unit and described microprocessor;Described Overvoltage protecting unit includes the first order Overvoltage crowbar and second level overvoltage crowbar;
Described first order overvoltage crowbar is for comparing described sampled voltage with first order protection voltage signal And it is more than output overvoltage signal when the described first order protects voltage signal at described sampled voltage;
Described second level overvoltage crowbar is for comparing described sampled voltage with second level protection voltage signal And it is more than output overvoltage signal when voltage signal is protected in the described second level at described sampled voltage;The described first order Protection voltage signal protects voltage signal less than the described second level.
Pacemaking generation device the most according to claim 2, it is characterised in that described first order protection electricity Pressure signal is adjustable voltage signal, described microprocessor be set according to described target voltage values;Described Second level protection voltage signal is fixed voltage signal, according to the maximum operating voltage of described pacemaking generation device Determine.
Pacemaking generation device the most according to claim 2, it is characterised in that described first order overvoltage is protected Protection circuit includes the first comparator, the first resistance and the first diode;The input of described first comparator divides Do not protect voltage signal inputs for sampled voltage input and the first order;The outfan of described first comparator It is connected with described first resistance, described first diode respectively;Described first resistance is also with power input even Connect;The negative electrode of described first diode is also connected with described microprocessor, described boosting unit;
Described second level overvoltage crowbar includes the second comparator, the second resistance, the 3rd resistance, the 4th electricity Resistance and the second diode;The input of described second comparator is respectively sampled voltage input and the second level Protection voltage signal inputs;Protection voltage signal in the described second level is by described second resistance and described 3rd electricity Resistance dividing potential drop is formed;The outfan of described second comparator is connected with described 4th resistance, the second diode respectively; Described 4th resistance is also connected with described power input;The negative electrode of described second diode is also with described first The negative electrode of diode connects.
Pacemaking generation device the most according to claim 1, it is characterised in that also include overcurrent protection list Unit and current sampling unit;Described current sampling unit is connected with described constant-current source, for described constant-current source The pacemaker current of output carries out sampling and exporting sample rate current;Described over-current protecting unit respectively with described electric current Sampling unit, described constant-current source and described microprocessor connect;Described over-current protecting unit includes the first order Current foldback circuit and second level current foldback circuit;
Described first order current foldback circuit is for comparing described sample rate current with first order protective current signal And described sample rate current more than the described first order protective current signal time output overcurrent signal;
Described second level current foldback circuit is for comparing described sample rate current with second level protective current signal And described sample rate current more than the described second level protective current signal time output overcurrent signal;The described first order Protective current signal is less than described second level protective current signal.
Pacemaking generation device the most according to claim 5, it is characterised in that described first order protection electricity Stream signal is adjustable current signal, described microprocessor be set according to described target pacemaker current signal; Described second level protective current signal is fixed current signal, according to the maximum functional of described pacemaking generation device Electric current determines.
Pacemaking generation device the most according to claim 5, it is characterised in that the described first order is crossed stream and protected Protection circuit includes the 3rd comparator, the 5th resistance, the 3rd diode;The input of described 3rd comparator divides Wei sample rate current input and first order protective current signal input part;The outfan of described 3rd comparator It is connected with described 5th resistance, described 3rd diode respectively;Described 5th resistance is also with power input even Connect;The negative electrode of described 3rd diode is also connected with microprocessor, described constant-current source;
Described second level current foldback circuit includes the 4th comparator, the 6th resistance, the 7th resistance, the 8th electricity Resistance and the 4th diode;The input of described 4th comparator is respectively sample rate current input and the second level Protective current signal input part;Second level protective current signal input part is connected to described 6th resistance and described Between 7th resistance;Described 6th resistance is also connected with power input, another termination of described 7th resistance Ground;The outfan of described 4th comparator is connected with described 8th resistance, described 4th diode the most respectively; Described 8th resistance is also connected with described power input;The negative electrode of described 4th diode is also with the described 3rd The negative electrode of diode connects.
Pacemaking generation device the most according to claim 7, it is characterised in that the described first order is crossed stream and protected Protection circuit also includes the first latching circuit;Described first latching circuit is connected to the output of described 3rd comparator End and sample rate current input;Described second level current foldback circuit also includes the second latching circuit;Described Two latching circuits are connected to outfan and the sample rate current input of described 4th comparator.
Pacemaking generation device the most according to claim 7, it is characterised in that described over-current protecting unit Also included stream reset circuit;Described stream reset circuit of crossing includes the first audion and the 9th resistance;Described The base stage of one audion is connected with described microprocessor, resets for receiving the stream of crossing of described microprocessor output Signal;The colelctor electrode of described first audion respectively with the sample rate current input of described 3rd comparator, The sample rate current input of four comparators connects;Emitter stage described 9th resistance of series connection of described first audion Rear ground connection.
Pacemaking generation device the most according to claim 7, it is characterised in that described current sample list Unit includes operational amplifier, the first sampled point and the second sampled point;Described first sampled point and described second is adopted Sampling point lays respectively at the diverse location of described constant-current source;Described first sampled point, described second sampled point are respectively It is connected with first input end, second input of described operational amplifier;Described second sampled point is also with described The sample rate current input of the 3rd comparator connects;The outfan of described operational amplifier compares with the described 4th The sample rate current input of device connects.
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