CN105963046B - Laboratory rodent waking state behavioral medicine detects special trace amount administration device - Google Patents
Laboratory rodent waking state behavioral medicine detects special trace amount administration device Download PDFInfo
- Publication number
- CN105963046B CN105963046B CN201610403394.4A CN201610403394A CN105963046B CN 105963046 B CN105963046 B CN 105963046B CN 201610403394 A CN201610403394 A CN 201610403394A CN 105963046 B CN105963046 B CN 105963046B
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- CN
- China
- Prior art keywords
- magnetic
- syringe needle
- adsorption
- sleeve pipe
- trace amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000002618 waking effect Effects 0.000 title claims abstract description 14
- 239000003814 drug Substances 0.000 title claims abstract description 13
- 241000283984 Rodentia Species 0.000 title claims abstract description 12
- 230000003542 behavioural effect Effects 0.000 title claims abstract description 12
- 238000001179 sorption measurement Methods 0.000 claims abstract description 36
- 238000010171 animal model Methods 0.000 claims abstract description 7
- 238000005070 sampling Methods 0.000 claims description 11
- 239000000696 magnetic material Substances 0.000 claims description 3
- 206010016276 Fear of animals Diseases 0.000 abstract description 3
- 201000002426 animal phobia Diseases 0.000 abstract description 3
- 230000007812 deficiency Effects 0.000 abstract description 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 6
- 102000004877 Insulin Human genes 0.000 description 3
- 108090001061 Insulin Proteins 0.000 description 3
- 229940125396 insulin Drugs 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000000844 transformation Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention discloses a kind of laboratory rodent waking state behavioral medicine to detect special trace amount administration device, including pre- embedding sleeve pipe, syringe needle and thin wire, described sleeve pipe and the specification of syringe needle cooperate, described sleeve pipe is located at the external end sleeve of experimental animal and is provided with magnetic-adsorption portion, the end of the syringe needle is arranged with magnetic-adsorption auxiliary section, magnetic-adsorption portion and magnetic-adsorption auxiliary section composition the magnetic-adsorption mechanism.The present invention is provided with magnetic-adsorption mechanism on pre- embedding sleeve pipe and syringe needle, when syringe needle is inserted in sleeve pipe, can be acted on by magnetic-adsorption and realize that syringe needle is inserted in quickly, shortened the operating time, reduce the fear of animal；Syringe needle connects the transparent thin wire with master scale, convenient to realize getting it filled and being administered compared with standard；Thin wire rear connects sacculus, gets it filled and is administered by sacculus realization is squeezed, avoids relying on the deficiency that microscale sampler is brought.
Description
Technical field
The present invention relates to a kind of delivery device, and in particular to a kind of laboratory rodent waking state behavioral medicine detection is special
Use trace amount administration device.
Background technology
The ethological detection of experimental animal often requires that and recorded under waking state, particularly require under waking state to
Medicine simultaneously detects.Administration for experimental animal telocoele or a certain core group is, it is necessary to which five days in advance to one week embedding conduit, existing
Conduit mostly forms for No. 5 syringe needle transformations, and administering mode is that hollow thin wire is connected using microsyringe, thin wire tip
Insulin syringe needle is reconnected to come.When to be administered, assistant is needed to fix animal, insulin needle headgear enters sleeve pipe embedding in advance, regains consciousness
Administration and Testing index under state.
The problem of conventional method is present has：(1) experimental animal is difficult to coordinate when syringe needle is inserted in sleeve pipe, time-consuming longer, has
When animal struggle syringe needle bending；(2) self-made wire both ends connect insulin syringe needle and microsyringe respectively, and Reusability is easy
Gas leakage；(3) scale of getting it filled relies on microsyringe, if gas leakage sampling amount has error.
The content of the invention
It is an object of the invention to overcome the above-mentioned problems in the prior art, there is provided a kind of laboratory rodent is clear
The state of waking up behavioral medicine detects special trace amount administration device.
To realize above-mentioned technical purpose and the technique effect, the present invention is to be achieved through the following technical solutions：
A kind of laboratory rodent waking state behavioral medicine detects special trace amount administration device, including pre- embedding set
The specification of pipe, syringe needle and thin wire, described sleeve pipe and syringe needle cooperates, and described sleeve pipe is located at the external end sleeve of experimental animal
Provided with magnetic-adsorption portion, the end of the syringe needle is arranged with magnetic-adsorption auxiliary section, and the magnetic-adsorption portion and magnetic-adsorption are matched somebody with somebody
Composition magnetic-adsorption mechanism of conjunction portion.
Further, the thin wire is the transparent wire with master scale.
Further, the one end of the thin wire is connected with syringe needle, and the other end, which is connected with, picks and places sampling device.
Further, the sampling device that picks and places is squeezable sacculus.
Further, the sacculus is provided with the piston for being easy to extruding.
Further, the magnetic-adsorption portion and magnetic-adsorption auxiliary section are made by magnetic material.
The beneficial effects of the invention are as follows：
1st, magnetic-adsorption mechanism is provided with pre- embedding sleeve pipe and syringe needle, can be by magnetic force when syringe needle is inserted in sleeve pipe
Suction-operated realizes that syringe needle is inserted in quickly, shortens the operating time, reduces the fear of animal.
2nd, syringe needle connects the transparent thin wire with master scale, convenient to realize getting it filled and being administered compared with standard.
3rd, thin wire rear connection pick and place sampling device, pick and place sampling device and select sacculus, by squeeze sacculus realize get it filled with
Administration, avoids relying on the deficiency that microscale sampler is brought.
Certainly, any product for implementing the present invention it is not absolutely required to reach all the above advantage simultaneously.
Brief description of the drawings
In order to illustrate the technical solution of the embodiments of the present invention more clearly, used required for being described below to embodiment
Accompanying drawing is briefly described, it should be apparent that, drawings in the following description are only some embodiments of the present invention, for ability
For the those of ordinary skill of domain, on the premise of not paying creative work, it can also be obtained according to these accompanying drawings other attached
Figure.
Fig. 1 is the structure that laboratory rodent waking state behavioral medicine of the present invention detects special trace amount administration device
Schematic diagram；
In accompanying drawing, the list of parts representated by each label is as follows：
1- sleeve pipes, 2- syringe needles, 3- thin wires, 4- magnetic-adsorptions portion, 5- magnetic-adsorptions auxiliary section, 6- pick and place sampling device.
Embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete
Site preparation describes, it is clear that described embodiment is only part of the embodiment of the present invention, rather than whole embodiments.It is based on
Embodiment in the present invention, those of ordinary skill in the art are obtained all other under the premise of creative work is not made
Embodiment, belong to the scope of protection of the invention.
Refer to shown in Fig. 1, the present invention detects special micro for a kind of laboratory rodent waking state behavioral medicine
The specification of delivery device, including pre- embedding sleeve pipe 1, syringe needle 2 and thin wire 3, described sleeve pipe 1 and syringe needle 2 cooperates, sleeve pipe 1
The end sleeve external positioned at experimental animal is provided with magnetic-adsorption portion 4, and the end of syringe needle 2 is arranged with magnetic-adsorption auxiliary section 5, magnetic force
Adsorption section 4 and magnetic-adsorption auxiliary section 5 form magnetic-adsorption mechanism.
Wherein, thin wire 3 is the transparent wire with master scale.
Wherein, the one end of thin wire 3 is connected with syringe needle 2, and the other end, which is connected with, picks and places sampling device 6.
Wherein, it is squeezable sacculus to pick and place sampling device 6.
Wherein, sacculus is provided with the piston for being easy to extruding.
Wherein, magnetic-adsorption portion 4 and magnetic-adsorption auxiliary section 5 are made by magnetic material.
One of the present embodiment has particular application as：Magnetic-adsorption portion 4 is provided with pre- embedding sleeve pipe 1, is set on syringe needle 2
There is absorption auxiliary section 5, magnetic-adsorption portion 4 and magnetic-adsorption auxiliary section 5 form magnetic-adsorption mechanism, when syringe needle 2 is inserted in sleeve pipe 1
It can be acted on by magnetic-adsorption and realize that syringe needle 2 is inserted in quickly, shortened the operating time, reduce the fear of animal；Syringe needle 2 connects
The transparent thin wire 3 with master scale, it is convenient to realize getting it filled and being administered compared with standard；The connection of the rear of thin wire 3 picks and places sample dress
6 are put, sampling device 6 is picked and placeed and selects sacculus, gets it filled and is administered by sacculus realization is squeezed, avoid relying on microscale sampler and bring not
Foot.
In the description of this specification, the description of reference term " one embodiment ", " example ", " specific example " etc. means
Feature, which is lived, with reference to specific features, structure, the material that the embodiment or example describe is contained at least one implementation of the invention
In example or example.In this manual, identical embodiment or example are not necessarily referring to the schematic representation of above-mentioned term.
Moreover, specific features, structure, material or the feature of description can close in any one or more embodiments or example
Suitable mode combines.
Present invention disclosed above preferred embodiment is only intended to help and illustrates the present invention.Preferred embodiment is not detailed
All details are described, it is only described embodiment also not limit the invention.Obviously, according to the content of this specification,
It can make many modifications and variations.This specification is chosen and specifically describes these embodiments, is to preferably explain the present invention
Principle and practical application so that skilled artisan can be best understood by and utilize the present invention.The present invention is only
Limited by claims and its four corner and equivalent.
Claims (4)
1. a kind of laboratory rodent waking state behavioral medicine detects special trace amount administration device, including pre- embedding sleeve pipe
(1) specification of, syringe needle (2) and thin wire (3), described sleeve pipe (1) and syringe needle (2) cooperates, it is characterised in that：Described sleeve pipe
(1) magnetic-adsorption portion (4) are provided with positioned at the external end sleeve of experimental animal, the end of the syringe needle (2) is arranged with magnetic-adsorption
Auxiliary section (5), the magnetic-adsorption portion (4) and magnetic-adsorption auxiliary section (5) composition magnetic-adsorption mechanism, the thin wire (3)
For the transparent wire with master scale, the one end of the thin wire (3) is connected with syringe needle (2), and the other end is connected with
Pick and place sampling device (6).
2. laboratory rodent waking state behavioral medicine according to claim 1 detects special trace amount administration device, its
It is characterised by：The sampling device (6) that picks and places is squeezable sacculus.
3. laboratory rodent waking state behavioral medicine according to claim 2 detects special trace amount administration device, its
It is characterised by：The sacculus is provided with the piston for being easy to extruding.
4. laboratory rodent waking state behavioral medicine according to claim 1 detects special trace amount administration device, its
It is characterised by：The magnetic-adsorption portion (4) and magnetic-adsorption auxiliary section (5) are made by magnetic material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610403394.4A CN105963046B (en) | 2016-06-06 | 2016-06-06 | Laboratory rodent waking state behavioral medicine detects special trace amount administration device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610403394.4A CN105963046B (en) | 2016-06-06 | 2016-06-06 | Laboratory rodent waking state behavioral medicine detects special trace amount administration device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105963046A CN105963046A (en) | 2016-09-28 |
| CN105963046B true CN105963046B (en) | 2017-12-19 |
Family
ID=57011542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610403394.4A Expired - Fee Related CN105963046B (en) | 2016-06-06 | 2016-06-06 | Laboratory rodent waking state behavioral medicine detects special trace amount administration device |
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| Country | Link |
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| CN (1) | CN105963046B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107198592A (en) * | 2017-05-16 | 2017-09-26 | 于生元 | Rat inflammation soup stimulates model and method for building up |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004242758A (en) * | 2003-02-12 | 2004-09-02 | Enomoto Co Ltd | Medical catheter |
| CN100411698C (en) * | 2005-05-09 | 2008-08-20 | 黄国明 | safety syringe |
| KR200459830Y1 (en) * | 2009-10-30 | 2012-04-19 | (주)아모레퍼시픽 | Lipgloss case |
| US8668671B2 (en) * | 2010-08-26 | 2014-03-11 | Carefusion 303, Inc. | Automatic loading of IV pump cassette |
| CN204521962U (en) * | 2015-03-20 | 2015-08-05 | 潍坊医学院 | Brain micro-administration device |
| CN204839825U (en) * | 2015-07-10 | 2015-12-09 | 山西医科大学第二医院 | Novel experiment rattail intravenous route device |
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2016
- 2016-06-06 CN CN201610403394.4A patent/CN105963046B/en not_active Expired - Fee Related
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| Publication number | Publication date |
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| CN105963046A (en) | 2016-09-28 |
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| C10 | Entry into substantive examination | ||
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20171219 Termination date: 20190606 |