CN105878107A - Skin-care product composition for sensitive skin - Google Patents
Skin-care product composition for sensitive skin Download PDFInfo
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- CN105878107A CN105878107A CN201610230192.4A CN201610230192A CN105878107A CN 105878107 A CN105878107 A CN 105878107A CN 201610230192 A CN201610230192 A CN 201610230192A CN 105878107 A CN105878107 A CN 105878107A
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- 239000000203 mixture Substances 0.000 title claims abstract description 17
- 230000037307 sensitive skin Effects 0.000 title abstract description 18
- 235000007119 Ananas comosus Nutrition 0.000 claims abstract description 24
- 244000099147 Ananas comosus Species 0.000 claims abstract description 21
- 235000017309 Hypericum perforatum Nutrition 0.000 claims abstract description 17
- 244000141009 Hypericum perforatum Species 0.000 claims abstract description 16
- 241000196324 Embryophyta Species 0.000 claims abstract description 12
- 239000000284 extract Substances 0.000 claims description 42
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 35
- 239000002131 composite material Substances 0.000 claims description 16
- 239000007788 liquid Substances 0.000 claims description 16
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- 235000015459 Lycium barbarum Nutrition 0.000 claims description 9
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 9
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- 238000003756 stirring Methods 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
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- MPGWGYQTRSNGDD-UHFFFAOYSA-N hypericin Chemical compound OC1=CC(O)=C(C2=O)C3=C1C1C(O)=CC(=O)C(C4=O)=C1C1=C3C3=C2C(O)=CC(C)=C3C2=C1C4=C(O)C=C2C MPGWGYQTRSNGDD-UHFFFAOYSA-N 0.000 description 2
- 229940005608 hypericin Drugs 0.000 description 2
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- NQYPTLKGQJDGTI-FCVRJVSHSA-N hyperoside Natural products OC[C@H]1O[C@@H](OC2=C(Oc3cc(O)cc(O)c3[C@H]2O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@H]1O NQYPTLKGQJDGTI-FCVRJVSHSA-N 0.000 description 2
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- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 description 2
- 239000010410 layer Substances 0.000 description 2
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- OVSQVDMCBVZWGM-DTGCRPNFSA-N quercetin 3-O-beta-D-galactopyranoside Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1OC1=C(C=2C=C(O)C(O)=CC=2)OC2=CC(O)=CC(O)=C2C1=O OVSQVDMCBVZWGM-DTGCRPNFSA-N 0.000 description 2
- BBFYUPYFXSSMNV-UHFFFAOYSA-N quercetin-7-o-galactoside Natural products OC1C(O)C(O)C(CO)OC1OC1=CC(O)=C2C(=O)C(O)=C(C=3C=C(O)C(O)=CC=3)OC2=C1 BBFYUPYFXSSMNV-UHFFFAOYSA-N 0.000 description 2
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
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- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
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- MGRRGKWPEVFJSH-UHFFFAOYSA-N dianthrone Natural products C12=CC=CC=C2C(=O)C2=CC=CC=C2C1=C1C2=CC=CC=C2C(=O)C2=CC=CC=C21 MGRRGKWPEVFJSH-UHFFFAOYSA-N 0.000 description 1
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- 125000004494 ethyl ester group Chemical group 0.000 description 1
- GJQLBGWSDGMZKM-UHFFFAOYSA-N ethylhexyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(CC)CCCCC GJQLBGWSDGMZKM-UHFFFAOYSA-N 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
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- 229930195729 fatty acid Natural products 0.000 description 1
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- IWBJJCOKGLUQIZ-HQKKAZOISA-N hyperforin Chemical compound OC1=C(CC=C(C)C)C(=O)[C@@]2(CC=C(C)C)C[C@H](CC=C(C)C)[C@](CCC=C(C)C)(C)[C@]1(C(=O)C(C)C)C2=O IWBJJCOKGLUQIZ-HQKKAZOISA-N 0.000 description 1
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- 239000011148 porous material Substances 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
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- 230000037394 skin elasticity Effects 0.000 description 1
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- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses skin-care product composition for sensitive skin and particularly relates to skin-care product composition containing a common St.John's wort herb extracting solution, a fructus lycii extracting solution and a pineapple leaf extracting solution. The composition is prepared from natural plant ingredients, can penetrate through the surface layer of skin well, performs the function of strengthening the skin epidermal barrier, improves the state of the sensitive skin and is safe, mild and free of irritation.
Description
Technical field
The invention belongs to cosmetic field, relate to a kind of containing hypericum perforatum extract, medlar extract liquid and spinach
The skin care item of trailing plants leaf extract composition.
Background technology
In recent years, the problem that skin sensitivity causes is increasingly becoming the focus of cosmetic industry.What is more, because making
Improper with skin care item, cause skin health state more and more worse, for the people of sensitive skin, this is undoubtedly
It is to make the matter worse.
The epidermis of sensitive skin is the thinnest, and pore is the most tiny, skin is nonelastic, fair complexion, and appearance is seen
Get up delicate, the most sensitive, the serious fine vascular that can be seen that on the face.When skin surface is thinning,
Cuticula is the thinnest, and the water holding capacity of epidermis is deteriorated, and moisture is difficult to pin, the more inclined dryness of skin, skin pair
The defense reaction of extraneous stimulation is deteriorated, and easily produces the general symptom such as red of itch.
The mechanism of the sensitive skin of reparation, typically by strengthening skin epidermal barrier function, reduces skin susceptibility,
Strengthen skin moisture-keeping.Strengthen skin epidermal barrier to be mainly by supplementing cuticula composition regularly, increase cutin
The thickness of layer.Cuticula is the important protective layer of skin, its moisture-keeping functions can keep the softness of skin, exquisiteness,
Moistening, it is also prevented from moisture and volatilizees from inside to outside, the opposing energy force rate basalis of chemical substance and subcutaneous
Fat is strong.If skin is continued for coming to harm, lacking suitable maintenance, chemical substance will be unblocked
Ground invades skin internal layer, causes skin inflammation, redness, the symptom such as itch.Meanwhile, if keratoderma mistake
Coming off of degree, skin can produce the strongest mechanicalness to cosmetics and resist, and skin can redden, and continue not
Move back.The effect of releiving is the most critically important to improving sensitive skin, and reducing inflammation to reduce flows to be subject to as reflection defence
Stimulate the CBF in district, thus the corresponding red trace of blood can alleviate.Therefore, sensitive skin should keep the skin wet in time,
Strengthen epiderm skin barrier function, select gentle, safe, non-stimulated, the cosmetics of natural origin raw material, far
Safeguard measure is carried out while stimulus.
Capillary mainly repaired by cosmetics (such as Avene, manage skin spring) for sensitive skin in the market
It is main, removes the red trace of blood, but effect is less desirable.The present invention is according to sensitive skin feature, by adding sky
So vegetable composition, keeps the skin wet and anti-inflammatory while strengthening epiderm skin barrier function, reduces skin irritation,
Alleviate skin irritation sense, play the effect improving sensitive skin.
Summary of the invention
The technical problem that present invention mainly solves is to provide the composite skin care product of a kind of applicable sensitive skin, and it contains
Have hypericum perforatum extract, medlar extract liquid and the composition of pineapple leaves extract, play releive, moisturizing,
Strengthen epiderm skin barrier effect.
Concrete technical scheme is as follows:
Plant extraction liquid of the present invention is hypericum perforatum extract, medlar extract liquid and pineapple leaves extract
Mixed liquor.
Hypericum perforatum, has another name called Herba Hyperici Monogyni, is Guttiferae hypericum.The main work of Herba Hyperici Monogyni
Property composition be hyperforine, hypericin, Hyperoside, it is raw that China is conventionally used to detoxicating, relieving inflammation, hemostasis
Flesh, adjust blood work through etc. aspect.Hypericin belongs to dianthrone class, have antidepression, antiviral, hemostasis and anti-inflammation,
The effects such as analgesia.Hyperoside belongs to flavonoids, has antibacterial and anti-inflammatory activity.
Matrimony vine is plant of Solanaceae, is medicine food dual purpose plant, its fruits nutrition enrich, containing protein, fat,
Carbohydrate, crude fibre, mineral matter, carrotene and various trace elements.Matrimony vine is various in style, with
Lycium barbarum is the most famous.The fruit of Chinese wolfberry is the dry mature fruit of matrimony vine, and active component includes alkaloids, Huang
Ketone, amino acids, sterols, vitamins and organic acid etc., have stronger antibiotic property and antioxidant.
Pineapple is pineapple family Ananas plant, and one of famous tropical fruit (tree) originates in Brazil of South America,
China's planting area is mainly distributed on the ground such as Guangdong, Hainan and Fujian.Pineapple leaves is remaining after pineapple fruit is gathered in the crops
Discarded object, record according to " China book on Chinese herbal medicine ", pineapple leaves has help digestion conjunction stomach, diarrhea-relieving function, cures mainly heat in summer
Rush down, indigestion epigastric distending pain etc..Pineapple leaves contains abundant fiber, has style and the property of common flaxen fiber
Can, in addition with unique excellent natural disinfection characteristic, it is widely used as textile material.At present.Research is thought
Containing substantial amounts of aldehydes matter in pineapple leaves, have good anti-oxidant, Adjust-blood lipid is active.Existing scholar is from spinach
In trailing plants leaf, isolated third pacifies element class, amide-type and triterpene compound.The ethanol extract of pineapple leaves, has
Non-oxidizability and antibiotic property.
Heretofore described emulsifying agent is sorbitan fatty acid ester/ethylhexyl palmitate, cetearyl alcohol
One or more mixture in alcohol olive oil acid esters/sorb smooth olive oil acid esters, makes in an embodiment
Emulsifying agent be cetostearyl alcohol olive oil acid esters/sorb smooth olive oil acid esters.
Higher aliphatic of the present invention is the mixture of hexadecanol and octadecyl alcolol.
Vegetable oil of the present invention is Sweet Almond Oil, jojoba oil, Queensland nut seed oil, the one of olive oil
Or more than one mixing.Preferred described vegetable oil is the mixed of Sweet Almond Oil, jojoba oil and macadimia nut oil
Compound, the mass ratio of described Sweet Almond Oil, jojoba oil and Queensland nut seed oil is (1-4): (1-4): (1-4).
Sweet Almond Oil, rich in vitamin E, easily absorbs, and has good skin-friendly and moist, moisture-keeping efficacy；Jojoba
Oil, rich in vitamin E and mineral matter, can be thoroughly mixed with sebum, has minimizing transepidermal water and runs off and moisturizing
Effect, is particularly suitable for sensitive；Macadimia nut oil has good ductility and permeability, can be soft
Soft skin, delay lipid peroxidation, protect cell membrane, keep skin elasticity.
Esters of the present invention is in nutmeg isopropyl propionate, glycerin monostearate, isopropyl palmitate
Plant or more than one mixing.
NMF of the present invention is the mixture of propane diols and pyrrolidone sodium carboxylate, and both mass ratioes are
(1～5): (1～5).Pyrrolidone sodium carboxylate is a kind of NMF, has good moisture retention, it
Good with skin-friendliness, to no skin irritation, skin softness and elasticity can be promoted.
The skin care item of the present invention, described preservative is natural plant source antiseptic agent and/or bland preservative,
The preservative used in embodiment is Phenoxyethanol.
The hypericum perforatum extract of the present invention, medlar extract liquid and pineapple leaves extract, adopt and make with the following method
Standby:
Being dried hypericum perforatum herb to pulverize, add 70%～90% ethanol, 80 DEG C of backflows carry 2～3h, filter,
Hypericum perforatum extract.
Dried wolfberry smashes, and adds 70%～95% ethanol, and 90 DEG C are soaked backflow and carry 2～3h, filter, obtain Chinese holly
Matrimony vine extract.
Being dried pineapple leaves to pulverize, by 80%～95% alcohol immersion refluxing extraction 2～4h, reduced pressure concentration obtains ethanol and carries
Take thing, then dilute with water, centrifugal, use petroleum ether, chloroform, ethyl acetate to extract successively, extract is dense
Contracting is evaporated, and is dissolved in ethanol, and through chloroform-methanol gradient elution, after silica gel chromatographic column is analyzed, again with methanol is washed
De-, analyze to obtain pineapple leaves extract through gel chromatography.
The composite skin care product of the present invention is prepared via a method which:
(1) emulsifying agent, vegetable oil, esters, higher aliphatic are joined in dissolving pan, be stirred continuously and add
Heat, to 75～80 DEG C, is treated that each component is completely dissolved, is obtained oil phase A, standby；
(2) NMF, thickener are joined in deionized water, are stirred and heated to 90～100 DEG C, keep 30min,
It is cooled to 75～80 DEG C, obtains aqueous phase B, standby；
(3), under quickly stirring, A is added in B phase, homogeneous (2000～3000r/min) 5～10min,
Add triethanolamine, the insulated and stirred that stirs again 15～20min；
(4) cool to 35～40 DEG C, add plant extraction liquid and preservative, stir, regulation
PH=5.5～6.5, obtains composite skin care product.
Detailed description of the invention
Below in conjunction with specific embodiment, technical scheme is described further.
Hypericum perforatum extract, medlar extract liquid and the preparation method of pineapple leaves extract:
Being dried hypericum perforatum herb to pulverize, 1:15 in mass ratio adds 80% ethanol, in 80 DEG C of refluxing extraction 2h,
Filter, obtain hypericum perforatum extract.
Dried wolfberry smashes, and 1:10 in mass ratio adds 95% ethanol, soaks refluxing extraction 2h in 90 DEG C,
Filter, obtain medlar extract liquid.
Being dried pineapple leaves to pulverize, 1:10 in mass ratio adds 95% alcohol immersion refluxing extraction 2h, reduced pressure concentration
Remove ethanol, obtain ethanol extract, then dilute with water, centrifugal, use petroleum ether, chloroform, acetic acid successively
Ethyl ester extracts, and extract concentrates and is evaporated, and is dissolved in ethanol, through chloroform-methanol gradient elution, through silica gel chromatographic column
After analysis, again with methanol elutes, and analyzes to obtain pineapple leaves extract through gel chromatography.
The sensitive skin composite skin care product formula of embodiment 1-3 and comparative example 1-3 is shown in Table 1.
Table 1 is embodiment 1-3 and comparative example 1-3 formula table (each component is weight/mass percentage composition).
The sensitive skin composite skin care product formula of embodiment 4-6 and comparative example 4-6 is shown in Table 2.
Table 2 is embodiment 4-6 and comparative example 4-6 formula table (each component is weight/mass percentage composition).
The sensitive skin composite skin care product formula of embodiment 7-9 and comparative example 7-9 is shown in Table 3.
Table 3 is embodiment 7-9 and comparative example 7-9 formula table (each component is weight/mass percentage composition).
The sensitive skin composite skin care product formula of embodiment 10-12 and comparative example 10-12 is shown in Table 4.
Table 4 is embodiment 10-12 and comparative example 10-12 formula table (each component is weight/mass percentage composition).
The composite skin care product of above-described embodiment 1-12 and comparative example 1-12 is prepared by following preparation method:
(1) by cetostearyl alcohol olive oil acid esters/sorb smooth olive oil acid esters, Sweet Almond Oil, jojoba oil,
Macadimia nut oil, nutmeg isopropyl propionate, glycerin monostearate, isopropyl palmitate, hexadecanol, octadecyl alcolol
Join in dissolving pan, be stirred continuously and be heated to 75 DEG C, treat that each component is completely dissolved, obtain oil phase A, standby；
(2) carbomer, propane diols, pyrrolidone sodium carboxylate are joined in deionized water, be stirred and heated to
90～100 DEG C, keep 30min, be cooled to 75 DEG C, obtain aqueous phase B, standby；
(3) under quickly stirring, being added to by A in B phase, under 2500r/min rotating speed, homogeneous 7min, adds
Entering triethanolamine, stir insulated and stirred 20min again；
(4) cool to 35 DEG C, add plant extraction liquid and Phenoxyethanol, stir, regulate pH=5.8,
Obtain composite skin care product.
Embodiment application effect
Skin care item product prepared by above-described embodiment 1-12 and comparative example 1-12, continuous through 100 personnel respectively
Use 4 weeks.Test object: each experimental group is the sensitive skin women 100 of 20 years old～40 years old.Take 2～3g
Product uniform application, face, every day 2 times, persistently uses 4 weeks.After experiment terminates, test its skin of face
Be dried, furfur, tingling sensation and erythema situation, the results are shown in Table 5.
Table 5 is test result.
According to embodiment 1-12 and the test result of comparative example 1-12, in embodiment each product face is dried,
Furfur, tingling sensation and erythema to improve effect all effective than the improvement of control group, and composite skin care product passes through
The mass ratio of leaf capsule of weeping forsythia extract, medlar extract liquid and pineapple leaves extract is (2～10): (2～10): (2～10)
Time, improve best results.
The above, only have expressed the several embodiments of the present invention, the present invention not do any pro forma restriction,
Therefore without departing from the content of technical solution of the present invention, carry out deforming and improving according to the technical spirit of the present invention, all belong to
In the scope of protection of the invention.
Claims (5)
1. a composite skin care product, it is characterised in that contained component and each constituent mass divide
Number is as follows:
Described plant extraction liquid is that hypericum perforatum extract, medlar extract liquid and pineapple leaves carry
Take the mixed liquor of liquid, described hypericum perforatum extract, medlar extract liquid and pineapple leaves extract
Mass ratio is (1～15): (1～15): (1～15)；Described hypericum perforatum extract, the fruit of Chinese wolfberry
The preparation method of extract and pineapple leaves extract prepares according to following steps: be dried hypericum perforatum
Herb is pulverized, and adds 70%～90% ethanol, and 80 DEG C of backflows carry 2～3h, filter, and must pass through leaf even
Stick up extract；Dried wolfberry smashes, and adds 70%～95% ethanol, and 90 DEG C are soaked backflow and carry
2～3h, filter, obtain medlar extract liquid；It is dried pineapple leaves to pulverize, with 80%～95% ethanol
Soaking refluxing extraction 2～4h, reduced pressure concentration obtains ethanol extract, then dilute with water, centrifugal,
Using petroleum ether, chloroform, ethyl acetate to extract successively, extract concentrates and is evaporated, and is dissolved in ethanol,
Through chloroform-methanol gradient elution, after silica gel chromatographic column is analyzed, again with methanol elutes, through solidifying
Glue chromatography obtains pineapple leaves extract.
2. according to claim 1, it is characterised in that described hypericum perforatum extract, Chinese holly
Matrimony vine extract and pineapple leaves extract mass ratio are preferably (2～10): (2～10): (2～10).
Composite skin care product the most according to claim 1 or claim 2, it is characterised in that described
The mixture that NMF is propane diols and pyrrolidone sodium carboxylate, both mass ratioes are (1～5):
(1～5).
Composite skin care product the most according to claim 1 or claim 2, it is characterised in that described
The mixing that vegetable oil is Sweet Almond Oil, jojoba oil and macadimia nut oil, described Sweet Almond Oil,
Jojoba oil and macadimia nut oil mass ratio are (1～4): (1～4): (1～4).
5. according to any one in claim 1-4, described composite skin care product preparation side
Method, it is characterised in that following steps:
(1) emulsifying agent, vegetable oil, esters, higher aliphatic are joined in dissolving pan,
It is stirred continuously and is heated to 75～80 DEG C, treat that each component is completely dissolved, obtain oil phase A, standby；
(2) NMF, thickener are joined in deionized water, are stirred and heated to 90～100 DEG C,
Keep 30min, be cooled to 75～80 DEG C, obtain aqueous phase B, standby；
(3), under quickly stirring, oil phase is joined in aqueous phase, 2000～3000r/min rotating speeds
Under, homogeneous 5～10min, add triethanolamine, the insulated and stirred that stirs again 15～20min；
(4) cooling to 35～40 DEG C, add plant extraction liquid and preservative, stirring is all
Even, regulate pH=5.5～6.5, obtain composite skin care product.
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| CN108653158A (en) * | 2017-03-27 | 2018-10-16 | 上海莱妃化妆品有限公司 | There are the cosmetics and preparation method of auxiliary repair to sensitive skin |
| CN106955255B (en) * | 2017-03-28 | 2020-06-23 | 海南师范大学 | Pineapple leaf extract and application thereof as tyrosinase inhibitor |
| CN106924141B (en) * | 2017-03-28 | 2020-06-23 | 海南师范大学 | Preparation method of pineapple leaf extract applied to whitening field |
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