CN105815570A - Application of albumin tannate in preparation of feed additive for animals - Google Patents
Application of albumin tannate in preparation of feed additive for animals Download PDFInfo
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Abstract
The invention discloses application of albumin tannate in preparation of a feed additive for animals, and belongs to the field of feed additives. According to the application of the albumin tannate in preparation of the feed additive for the animals, the albumin tannate serves as a novel feed additive, is applied to breeding of livestock or poultry or aquatic animals at various growth stages, has a health-care effect on the animals, can improve the production performance of the animals and has an important market value in feed processing industries and animal breeding industries.
Description
Technical field:
The invention belongs to feed additive field, be specifically related to tannalbin application in preparing additive for animal feed, the especially application in preparation animal growth promoter.
Background technology:
The animal basal diet traditional original agricultural product of replacement that animal feed is the most required are applied in animal cultivation.People are often desirable to the animal growth at the minimum feedstuff efficient and healthful of the shortest time loss.In order to reach this purpose, the feed additive of various functions adds preparation in feedstuff in feed manufacturing process and becomes functional feed.Wherein, feeding antibiotic, zinc oxide or copper sulfate etc. are that the most conventional feed additive is for improving the production performance of animal and preventing and treating Animal diseases.But the life-time service of high dose inorganic zinc or Inorganic Copper class feed additive to animal dis at heavy metal toxicity；And the abuse of feeding antibiotic also causes the generation of microorganism drug resistance, drug residue and drug resistance transmission to threaten human health.The appearance of these problems causes conventional feed additive to use in animal cultivation being restricted or disable.Therefore, animal farming industry is had great importance by the efficient feed additive developing novel safety.
Summary of the invention:
It is an object of the invention to provide tannalbin application in preparing additive for animal feed, be applied in the aquaculture of animal as a kind of novel feed additive by tannalbin, the production performance improving animal reduces aquaculture cost.
Tannalbin is a kind of astringency, for enteritis, Non-bacterial diarrhea, eczema or the treatment of ulcer in human drugs.In field of veterinary, as intestinal regeneration agent to row's watery stools without or the animal diarrhea such as few band mucosa person there is cathartic or anti-diarrhea effect cleaning gastrointestinal.
The present invention is found through experiments, and its production performance is had while the health of laboratory animal is had certain health-care effect and is markedly improved effect by the cultivation of the animal that tannalbin is applied to the different breeding stage.
In a technical scheme, the tannalbin of 10-20000ppm is given the healthy small weaning pig spice with different tests group use, with not give any feed additive test control group compared with, the Incidence of Diarrhea of piglets substantially reduce while average daily gain be greatly improved and feedstuff conversion ratio tool be significantly improved effect.Additionally in the test group of high dose, the feed intake of test piglets is compared low dose group and the lifting of about 5% is occurred.
In another technical scheme, taking the tannalbin of doses to the healthy piglets spice with two monthly ages, average daily gain and the feed intake of the result display experiment piglets of experiment all have lifting, and the conversion ratio of feedstuff has the improvement effect of highly significant.
In another technical scheme, being taken with pig spice in the health at three monthly ages by the tannalbin of various dose, the tannalbin using dosage of 500-2000ppm, the production performance of test pig just shows significantly improves effect.
The tannalbin of the present invention can be applicable to poultry and the aquatic animal of each growth stage, and described poultry include the pig of each growth stage, cattle, sheep, horse, dog, mink, Nyctereutes procyonoides, rabbit, chicken, duck, goose, guinea fowl, Columba livia or Carnis Coturnicis japonicae.Described aquatic animal includes the fish of each growth stage, shrimp, Eriocheir sinensis or Chinese yellow eel.
In other technical schemes, tannalbin is applied in the cultivation of other cultivation healthy domestic animal such as cattle in stage, horse, sheep, donkey, Canis familiaris L., mink, Nyctereutes procyonoides, rabbit etc., the dosage selected is 1-20000ppm, make an addition in the basal diet of cultivated animals in the way of companion's material, during testing, animal is free choice feeding drinking-water, result according to statistics shows, it is that feedstuff sample feces or situation about having loose bowels the most does not occurs in gastrointestinal function in process of the test that the animal of cultivation the most significantly shows, and feces molding is good；It addition, the feed intake of animal gives any feed additive group close on the whole and not, but the average daily gain of cultivated animals but increases significantly, and the rate of returns of feedstuff significantly improves 0.5-10%.
In other technical schemes, tannalbin is applied to poultry such as chicken, duck, goose, Columba livia, guinea fowl, the cultivation of Carnis Coturnicis japonicae etc., the dosage selected is 100-10000ppm, inventor by the way of gavaging and feedstuff companion clothes mode give and cultivated animals, during testing, survival rate and performance index to animal are added up, the result of experiment shows, tannalbin is given with test group compared with the blank assay group not giving any feed additive, the survival rate of animal has promoted and the average daily gain of animal is also rising, the conversion ratio of feedstuff obtains the improvement effect of highly significant.
In another technical scheme, tannalbin is applied in the culture experiment of the aquatic animals such as shrimp, fish, Eriocheir sinensis or Chinese yellow eel in the way of spice, test the rate of body weight gain of aquatic animal, survival rate lifting it is obvious that the conversion ratio of feedstuff is also significantly improved.
In sum, tannalbin is applied in the cultivation of domestic animal, poultry or aquatic animal, has certain health-care effect to healthy animal and improve the production performance of animal in addition to diarrhoea animal is had effect of antidiarrheal.
Tannalbin is applied to prepare the feed additive of animal by the present invention.
Described feed additive has health-care effect to the health status of animal, additionally also further improves the production performance of animal, especially promotes the growth of animal, by the shortest time and most economical in the way of improve the production efficiency of animal cultivation.
Described feed additive is prepared according to existing industrial technology method with acceptable excipient, carrier, antioxidant, diluent, anti-caking agent, solvent or combinations thereof in preparation process.In one embodiment, described feed additive contains the material supplemented with balanced nutrients.In another embodiment, described feed additive is possibly together with health-related material.In another embodiment, described feed additive is possibly together with physiological regulation metabolism class material.In another embodiment, described feed additive is possibly together with increasing appetite aid digestion class material.In another embodiment, described feed additive is possibly together with processing and preservative agent class material.
Described feed additive can be liquid, solid, semisolid or gel.
On the one hand, the method that the invention still further relates to promote growth of animal, described method includes to the tannalbin of the present invention or feed additive prepared therefrom with animal effective dose.In one embodiment, the present invention provides described tannalbin or feed additive prepared therefrom add to independent form in every daily sustenance of animal and use.In another embodiment, the present invention provides described tannalbin or feed additive prepared therefrom are prepared as the Feed forms such as additive premix, concentrated feed, mixed feed, beneficiated burden material complemental feed according to a certain percentage for animal edible with feedstuff, feed additive, carrier or diluent etc..
The feedstuff that the present invention relates to refers to derive from animal, plant, microorganism or mineral, for processing and fabricating feedstuff but be not belonging to the feeding material of feed additive.
The feed additive that the present invention relates to refer to feed manufacturing, make, a small amount of or trace substance that use process is added, including nutritional feed additive and non-nutritional feed additive.Nutritional feed additive refers to a small amount of or trace substance mixing in feedstuff for supplement feed nutritional labeling, including feed grade aminoacid, vitamin, mineral trace element, enzyme preparation, non-protein nitrogen etc..Non-nutritional feed additive refers to a small amount of or trace substance for ensureing or improve feed quality, improve the effects such as efficiency of feed utilization and mixing in feedstuff.
The carrier that the present invention relates to refers to carry active component, improves its dispersibility, and have good chemical stability and an adsorptivity can feeding material.
The diluent that the present invention relates to refers to be uniformly distributed in material additive raw material, the additive raw material of high concentration is diluted to pre-mixing agent or the material of premix material of low concentration, micro constitutent can be separated from each other, reduce reacting to each other between active component, do not affect, to increase the stability of active component, the physico-chemical property having related substance.
The additive premix that the present invention relates to refers to that the nutritional feed additive more than by two kinds (classes) or two kinds (class) is main, the feedstuff prepared according to a certain percentage with carrier or diluent, including compound premixed feed, trace element premixing feed, vitamin premixed feed.
The concentrated feed that the present invention relates to refers to the feedstuff mainly having protein, mineral and feed additive to prepare according to a certain percentage.
The mixed feed that the present invention relates to refers to according to cultivated animals nutritional need, the feedstuff multiple feedstuff and feed additive prepared according to a certain percentage.
The concentrate supplement that the present invention relates to refers to the nutrition into supplementary plant-eating animal, the feedstuff multiple feedstuff and feed additive prepared according to a certain percentage.
The present invention provides tannalbin as a kind of novel feed additive, has health care to animal productiong and improves effect of production performance, having important market value in feed processing industry and animal farming industry.
Detailed description of the invention:
In order to describe the present invention, it is listed below embodiment.But it is to be understood that the invention is not restricted to these embodiments, only it is to provide the method putting into practice the present invention, helps to understand technical scheme.
Embodiment 1: tannalbin application effect in wean pig feed.
The wean pig of 200 28 age in days average weights 7.61kg, DLY ternary miscellaneous lean meat species piglets such as 1 point 10 groups of table that body weight is close, often organize 20.After each group is added the tannalbin of various dose in conventional creep feed (without any medicated feed additive, zinc oxide and high copper agent), free choice feeding and drinking-water, the average daily ingestion amount (ADFI) of each test group test pig, average daily gain (ADG) and the price of deed in adding up 10 days, without any medicated feed additive, zinc oxide, high copper agent and the test group of tannalbin during wherein matched group is conventional teaching material material.Result is as shown in table 1, as it can be seen from table 1 give in teaching material material during testing compared with the test group of tannalbin the growth performance of matched group experiment pig be improved significantly, additionally laboratory animal occurs the probability of diarrhoea also to occur being decreased obviously during testing.
Table 1 tannalbin influence research to the growth performance of wean pig
Embodiment 2: tannalbin is in the application effect in piglets stage
65 ages in days Du that 60 body weight are close greatly enhance ternary miscellaneous lean meat species piglets such as table 2 and are randomly divided into 6 groups, often organize 10.Each group is added laboratory sample as shown in table 2 and relevant dose in the piglets perfect compound feed without any feed additive, and 1-3 group is three repetitions of blank group.Experimental period free choice feeding and drinking-water.Totally 14 days experimental period, experimental period tannalbin group is all significantly improved (table 2) in terms of the weightening finish and feedstuff-meat ratio of test pig.During test, the piglets of all groups is all suffered from diarrhoea.
The result of the test that table 2 tannalbin is applied in pig feed
| Group | Experiment quantity | Substance | Dosage (mg/kg) | Average daily gain (kg/ head * d) | Feed consumption (kg) | Feedstuff-meat ratio |
| 1 | 10 | - | - | 0.58 | 131.0 | 2.40 |
| 2 | 10 | - | - | 0.59 | 127.5 | 2.41 |
| 3 | 10 | - | - | 0.58 | 136.2 | 2.39 |
| 4 | 10 | Tannalbin | 1000 | 0.66 | 148.6 | 2.25 |
| 5 | 10 | Tannalbin | 1000 | 0.67 | 146.2 | 2.23 |
| 6 | 10 | Tannalbin | 1000 | 0.63 | 147.0 | 2.27 |
Embodiment 3: tannalbin is in the application effect in middle pig stage
60 85 ages in days, DLY ternary miscellaneous lean meat species barren sow such as 3 points 4 groups of the table that body weight is close, often group 10.After each group is added the tannalbin of various dose in without the middle pig perfect compound feed of any feed additive, free choice feeding and drinking-water, add up average daily gain and the price of deed of 28 days each test group test pig.Result is as shown in table 3, from table 3 it can be seen that tannalbin is obvious to the improvement of test pig production performance during testing.During test, the test pig of all groups is not the most suffered from diarrhoea.
Table 3 tannalbin is in middle pig feed application effect and test packet
| Group | Size of animal | Additive | Dosage (ppm) | Average daily gain (g) | Feedstuff-meat ratio |
| 1 | 10 | - | - | 710 | 2.66 |
| 2 | 10 | Tannalbin | 500 | 723 | 2.51 |
| 3 | 10 | Tannalbin | 500 | 721 | 2.55 |
| 4 | 10 | Tannalbin | 1000 | 732 | 2.48 |
| 5 | 10 | Tannalbin | 1000 | 737 | 2.47 |
| 6 | 10 | Tannalbin | 2000 | 741 | 2.41 |
| 7 | 10 | Tannalbin | 2000 | 742 | 2.42 |
Embodiment 4: tannalbin application effect in chicken material.
The 1800 plumage 1 the biggest yellow-feather broilers of age in days are randomly divided into 9 test group, and each test group comprises 4 parallel test groups, and each parallel test group is 50 plumages, and is often organizing the tannalbin adding various dose in feedstuff respectively.Experimental period, raises in cages, free choice feeding and freely drinking water, totally 28 days experimental period, average daily gain (ADG) peace all feedstuff-meat ratios (AFCR) of each test group test chicken in adding up 28 days, wherein the 1st group be blank group be the experiment test group without any feed additive and tannalbin.Result of the test shows, compared with blank group, it is notable (table 4) that the production performance of tannalbin test group test chicken promotes effect.During test, the most there is not dysentery in the test chicken of all groups.
Table 4 tannalbin application effect in broiler material
| Group | Size of animal (only) | Test drug | Dosage (ppm) | ADG(g) | AFCR |
| 1 | 50×4 | Blank group | 0 | 34.6 | 2.105 |
| 2 | 50×4 | Tannalbin | 100 | 34.7 | 2.102 |
| 3 | 50×4 | Tannalbin | 200 | 34.8 | 2.096 |
| 4 | 50×4 | Tannalbin | 400 | 35.2 | 2.072 |
| 5 | 50×4 | Tannalbin | 800 | 35.7 | 2.043 |
| 6 | 50×4 | Tannalbin | 1200 | 36.1 | 2.017 |
| 7 | 50×4 | Tannalbin | 2400 | 36.7 | 1.985 |
| 8 | 50×4 | Tannalbin | 5000 | 37.4 | 1.946 |
| 9 | 50×4 | Tannalbin | 10000 | 38.2 | 1.907 |
Embodiment 5: the tannalbin of various dose application in fleshy duck fodder
800 Growth of Cherry Valley 1 age in days ducklings according to 5 points 8 groups of table, 100/group, in same foundation daily ration, add the tannalbin of various dose, free choice feeding and drinking-water, feed 30 days continuously, the production performance of statistical test duck.In terms of result of the test, tannalbin can significantly improve meat-type duck production performance (table 5).During test, the most there is not dysentery in the meat-type duck of all groups.
The tannalbin of the table 5 various dose growth-promoting effect result of the test to meat-type duck
| Group | Additive | Dosage (ppm) | Average daily gain/g | Average feedstuff-meat ratio |
| 1 | Matched group | 0 | 55.8 | 2.161 |
| 2 | Tannalbin | 100 | 56.1 | 2.151 |
| 3 | Tannalbin | 200 | 56.8 | 2.139 |
| 4 | Tannalbin | 300 | 57.4 | 2.112 |
| 5 | Tannalbin | 400 | 59.8 | 2.094 |
| 6 | Tannalbin | 800 | 61.6 | 2.047 |
| 7 | Tannalbin | 1600 | 65.0 | 2.012 |
| 8 | Tannalbin | 3200 | 67.2 | 2.009 |
Embodiment 6: tannalbin application effect in Ctenopharyngodon idellua feed
Test fish used is Ctenopharyngodon idellus, Aquatic product field, English Saite test site, Guangzhou carry out.The Mylopharyngodon piceus kind that bouncing, specification are consistent raise in large cage 4 weeks after just for formal culture experiment, experimental system is buoyancy small-sized net cage.Small-sized net cage is placed in one, test site 3500m with the most foster net cage2Pond in, the pond depth of water～1.5m, pond water is water under abundant aeration.During test, Ctenopharyngodon idellus 240 tail of hungry 1d being randomly divided into 6 groups, often group sets 4 repetitions, and each repetition puts 10 tail fishes, and entirety is put in 16 net cages after weighing at random, feeds different test feeds respectively.Test feedstuff is prepared voluntarily.Different tests group is separately added into the tannalbin of various dose in the feedstuff prepared voluntarily.Test uses artificial limit food to throw something and feed, and feeding amount adjusts weekly once, and two groups of levels of throwing something and feeding (by original body mass) are completely the same, and throw something and feed every day twice (7:30 and 15:00).Test 8 weeks by a definite date.
Tannalbin is shown in Table 6 to the growth promotion result of the test of fish.Result display is added the test group of tannalbin and is superior to blank group in terms of weightening finish, feed coefficient and survival rate, has obvious growth enhancing effect.
Table 6 tannalbin application test in Ctenopharyngodon idellua feed is grouped and result
Above-described embodiment is the present invention preferably embodiment; but embodiments of the present invention are also not restricted to the described embodiments; the change made under other any spirit without departing from the present invention and principle, modify, substitute, combine, simplification etc. all should be the substitute mode of equivalence, within being included in protection scope of the present invention.
Claims (7)
1. tannalbin application in preparing additive for animal feed.
Application the most according to claim 1, it is characterised in that described additive for animal feed is animal growth promoter.
Application the most according to claim 2, it is characterised in that the using dosage of described animal growth promoter is calculated as 1-20000ppm with tannalbin.
Application the most according to claim 3, it is characterised in that the using dosage of described animal growth promoter is calculated as 100-10000ppm with tannalbin.
Application the most according to claim 1, it is characterised in that described animal includes poultry and aquatic animal.
Application the most according to claim 5, it is characterised in that described poultry include the pig of each growth stage, cattle, sheep, horse, dog, mink, Nyctereutes procyonoides, rabbit, chicken, duck, goose, guinea fowl, Columba livia or Carnis Coturnicis japonicae.
Application the most according to claim 5, it is characterised in that described aquatic animal includes the fish of each growth stage, shrimp, Eriocheir sinensis or Chinese yellow eel.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108042558A (en) * | 2017-12-12 | 2018-05-18 | 长沙拜特生物科技研究所有限公司 | Avermectin preparation used for aquiculture and preparation method thereof |
| CN109287869A (en) * | 2018-10-11 | 2019-02-01 | 安佑生物科技集团股份有限公司 | The application of a kind of preparation method and tannalbin of tannalbin in animal feed |
| CN111053886A (en) * | 2020-01-10 | 2020-04-24 | 河南天昊鸿发生物技术有限公司 | Traditional Chinese medicine additive for treating poultry intestinal diseases, pharmaceutical composition containing traditional Chinese medicine additive, and preparation method and application of pharmaceutical composition |
| CN112753862A (en) * | 2020-12-30 | 2021-05-07 | 五峰赤诚生物科技股份有限公司 | Preparation method of tannalbin for feed and prepared tannalbin |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108042558A (en) * | 2017-12-12 | 2018-05-18 | 长沙拜特生物科技研究所有限公司 | Avermectin preparation used for aquiculture and preparation method thereof |
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| CN111053886A (en) * | 2020-01-10 | 2020-04-24 | 河南天昊鸿发生物技术有限公司 | Traditional Chinese medicine additive for treating poultry intestinal diseases, pharmaceutical composition containing traditional Chinese medicine additive, and preparation method and application of pharmaceutical composition |
| CN112753862A (en) * | 2020-12-30 | 2021-05-07 | 五峰赤诚生物科技股份有限公司 | Preparation method of tannalbin for feed and prepared tannalbin |
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