CN105784986B - A kind of full-automatic sample detection immunity analysis instrument of strip formula - Google Patents
A kind of full-automatic sample detection immunity analysis instrument of strip formula Download PDFInfo
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- CN105784986B CN105784986B CN201610279474.3A CN201610279474A CN105784986B CN 105784986 B CN105784986 B CN 105784986B CN 201610279474 A CN201610279474 A CN 201610279474A CN 105784986 B CN105784986 B CN 105784986B
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- 238000001514 detection method Methods 0.000 title claims abstract description 94
- 238000004458 analytical method Methods 0.000 title claims abstract description 36
- 230000036039 immunity Effects 0.000 title claims abstract description 32
- 238000005070 sampling Methods 0.000 claims abstract description 13
- 239000000084 colloidal system Substances 0.000 claims abstract description 6
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims abstract description 6
- 239000010931 gold Substances 0.000 claims abstract description 6
- 229910052737 gold Inorganic materials 0.000 claims abstract description 6
- 238000004140 cleaning Methods 0.000 claims description 12
- 239000007853 buffer solution Substances 0.000 claims description 8
- 238000007689 inspection Methods 0.000 claims description 6
- 238000013519 translation Methods 0.000 claims description 3
- 239000000872 buffer Substances 0.000 claims description 2
- 235000013399 edible fruits Nutrition 0.000 claims 1
- 238000012360 testing method Methods 0.000 abstract description 9
- 238000004445 quantitative analysis Methods 0.000 abstract description 6
- 238000004587 chromatography analysis Methods 0.000 abstract description 5
- 238000003018 immunoassay Methods 0.000 abstract description 5
- 238000000034 method Methods 0.000 abstract description 5
- 230000008569 process Effects 0.000 abstract description 4
- 239000007788 liquid Substances 0.000 description 9
- 239000000243 solution Substances 0.000 description 7
- 230000008859 change Effects 0.000 description 5
- 239000002699 waste material Substances 0.000 description 5
- 239000000463 material Substances 0.000 description 3
- 230000008901 benefit Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000012935 Averaging Methods 0.000 description 1
- 206010018910 Haemolysis Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 241000287127 Passeridae Species 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 230000008588 hemolysis Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000004973 liquid crystal related substance Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 239000002096 quantum dot Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000003245 working effect Effects 0.000 description 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5302—Apparatus specially adapted for immunological test procedures
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
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- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
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- Medicinal Chemistry (AREA)
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- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The invention discloses a kind of full-automatic sample detection immunity analysis instruments of strip formula, it can carry out colloid gold immune quantitative analysis and fluorescence immunoassay quantitative analysis, it includes casing, the rotary sample disk and strip rotating disk that can be rotatably set to around Pivot Point Center line on casing, rotating driving device for driving rotary sample disk and strip rotation disc spins, loading component, detection components and output precision, it realizes sample cell with strip rotating disk by rotary sample disk and detects automatically delivering for strip respectively, by loading component automatically from sampling and discharged to corresponding detection strip in sample cell to be detected, sample is detected by detection components automatically again after completing chromatography process on detection strip, testing result is finally exported by output precision automatically.The immunity analysis instrument realizes automatic loading and automatic detection, the error for avoiding manual operation from bringing, and can realize the purpose that single sample detection and small lot continuously detect, simple in structure, energy saving space and cost.
Description
Technical field
The present invention relates to medical examination equipment field more particularly to a kind of completely new full-automatic sample detection of strip formula are immune
Analyzer.
Background technology
According to statistics, the medical present situation of China is that 50% public hospital shunts 90% patient at present, and 50% Civilian Hospital is only
Occupy 10% patient's flow, shared medical institutions about 26000 of China in 2014, wherein about 50% is public hospital, over nearly 5 years
Public hospital's quantity is without significant change, but patient's flow of China 90% is in public hospital, especially large-scale tertiary hospitals.It is public
Hospital resources are limited, and patient's flow is but growing on and on or even occurs the super crowding phenomenon of ill no doctor；And basic hospital is exactly
On the contrary, there is doctor disease-free, you can catch sparrows on the doorstep, and medical resource cannot be utilized adequately and reasonably.
In order to alleviate current medical pressure, the effect of medical resource is given full play to, country has put into effect a series of reforms and arranged
It applies, classification medical treatment also just becomes the effective means for alleviating current medical pressure, is carried out with the popularization of classification medical treatment measure, counties and townships
Grade medical institutions and community sanitary institute will treat place as the Main Diagnosis of common disorder.The bases such as county, township, community cure at present
It is because insufficient funds impotentia is equipped with large-scale inspection equipment that the present situation for the treatment of mechanism, which has two classes, one kind, and another kind of is to have been equipped with
Large-scale instrument is but unable to get and makes full use of because cumbersome or human resources are short.Under such a social overall situation,
Basic medical unit just there is an urgent need to it is a kind of quickly, accurately, automatically detect, can individually also batch operation, it is economical
The analyzer of material benefit.
Current existing strip formula immunity analysis instrument has single also to have multi-channel mode, the analysis of single
Instrument is although inexpensive, cannot carry out batch detection, although the analyzer of multichannel can carry out batch detection, but each inspection
Surveying channel all needs be furnished with individual detection module, and the price of equipment can significantly increase, can not accomplish it is economical and practical, and no matter
Single channel or multi-channel detection analyzer be all manual loading or semi-automatic loading chromatography rear be detected, Wu Fada
To the requirement of full-automatic sample detection, artificial error cannot also avoid completely, be unable to reach and examine accurate basic demand.
Invention content
The purpose of the invention is to overcome the prior art, it is immune to provide a kind of full-automatic sample detection of strip formula
Analyzer.
In order to achieve the above objectives, the technical solution adopted by the present invention is：A kind of immune point of full-automatic sample detection of strip formula
Analyzer, the immunity analysis instrument include casing, can around Pivot Point Center line rotatably be set to the casing on rotary sample disk with
Strip rotating disk, the rotating driving device for driving the rotary sample disk and strip rotation disc spins, the rotary sample
Compartment of terrain is equipped with multiple accommodating structures for fixed placement sample cell, the upper end of the strip rotating disk in the circumferential sides of disk
Face is equipped with multiple card slots for placing one or a set of detection strip, and all card slots are in the strip rotating disk upper edge
Circumferentially-spaced distribution, the number of the card slot card slot consistent and all with the number of the accommodating structure with it is all
The position of the accommodating structure in the circumferential corresponds,
The immunity analysis instrument further includes loading component and detection components, and the loading component is included at least and is slidably set to
It can stretch on the casing and up and down upper to corresponding detection strip to be discharged from sampling in the sample cell and by sample
Sample needle, the detection components are again detected the detection strip by preset time after the detection strip is released sample
It analyzes, the output precision of the testing result for accordingly exporting the detection components is additionally provided on the casing.
Preferably, the strip rotating disk is fixedly superimposed upon the upper end of the rotary sample disk, and the strip rotates
Disk is synchronously rotated with rotary sample coiling shaft.
It is further preferred that the accommodating structure is to be opened in the rotary sample disk circumferential sides in half column shape
Storage tank, the single sample cell can be ordinatedly fastened in the storage tank, and the diameter of the strip rotating disk is less than institute
It states the diameter of rotary sample disk and the circumferential edge of the strip rotating disk is made to be located at the inside of the storage tank.
Further, all card slots are circumferentially evenly spaced apart to be distributed in the strip rotating disk, own
The accommodating structure be evenly spaced apart to be distributed in the outside circumference of the rotary sample disk, all card slots with it is all
The accommodating structure correspond.
As a kind of specific embodiment, the center line of each storage tank and the corresponding card slot is in water
Projection in plane extends along same rectilinear direction and perpendicular to the axial line of the shaft, and the loading needle is revolved along the sample
Sampling and release sample are realized in the translation of the radial direction of turntable or the strip rotating disk.
Preferably, the immunity analysis instrument further includes the sample identification of sample message on the rotary sample disk for identification
Component is detected into the sample that row information identifies through the loading component loading and the detection components through the sample recognizer component
Afterwards, output testing result is corresponded to by the output precision.
It is further preferred that the sample recognizer component is the scanning mould for reading label information on the sample cell
Block, the scan module are set to the side on the casing and positioned at the rotary sample disk.
Preferably, the detection components are set on the colloid gold immune detection module of the top of the strip rotating disk or glimmering
Light immunoassay detection module.
Preferably, the loading needle includes needle holder, syringe needle that can be flexible up and down in the needle holder, is also set on the needle holder
There is level sensor and sampling is realized with the collapsing length for controlling the syringe needle, the loading component further includes described for providing
The Buffer Unit of sample needle buffer solution and cleaning assembly for being cleaned to the loading needle.
Preferably, the casing is the babinet with side door, and the rotary sample disk, strip rotating disk and loading component are equal
In the babinet, the output precision includes the display screen set on the top of the box.
Due to the application of the above technical scheme, the present invention has following advantages compared with prior art：The strip of the present invention
The full-automatic sample detection immunity analysis instrument of formula, can carry out colloid gold immune quantitative analysis and fluorescence immunoassay quantitative analysis, wherein logical
Setting rotary sample disk is crossed with strip rotating disk to realize sample cell respectively and detect automatically delivering for strip, passes through loading component
Automatically from sampling and being discharged to corresponding detection strip in sample cell to be detected, sample completes chromatography on detection strip
It is detected automatically by detection components again after process, testing result is finally exported by output precision automatically.The immunity analysis instrument realizes
Automatic loading and automatic detection, the error for avoiding manual operation from bringing, and can realize that single sample detection and small lot are continuously examined
The purpose of survey, simple in structure, small volume, energy saving space more save cost.
Description of the drawings
Attached drawing 1 is the stereogram of the immunity analysis instrument of the present invention；
Attached drawing 2 is the stereogram of the immunity analysis instrument internal structure of the present invention；
Attached drawing 3 is the subregion schematic diagram of strip rotating disk on the immunity analysis instrument of the present invention；
Attached drawing 4 be the present invention immunity analysis instrument in loading component structural schematic diagram；
Wherein：1, casing；1a, side door；2, rotary sample disk；2a, storage tank；3, strip rotating disk；3a, card slot；4, on
Sample component；41, loading needle；41a, needle holder；41b, syringe needle；42, level sensor；43, buffer solution bottle；44, cleaning solution bottle；45、
Waste liquid bottle；5, sample recognizer component；6, detection components；7, display screen；8, shaft；9, sliding rail.
Specific implementation mode
Technical scheme of the present invention is further elaborated with specific embodiment below in conjunction with the accompanying drawings.
Shown in Fig. 1 to Fig. 4, a kind of full-automatic sample detection immunity analysis instrument of strip formula comprising casing 1, can be around
Pivot Point Center line rotatably be set to casing 1 on rotary sample disk 2 and strip rotating disk 3, for drive rotary sample disk 2 with card
The rotating driving device that rotating disk 3 rotates, compartment of terrain, which is equipped with, in the circumferential sides of rotary sample disk 2 multiple is used for fixed placement
The accommodating structure of sample cell, the upper surface of strip rotating disk 3 be equipped with it is multiple for placing the card slot 3a for detecting strip, it is all
Card slot 3a is circumferentially spaced in strip rotating disk 3, the number of the number and accommodating structure on rotary sample disk 2 of card slot 3a
Consistent and all card slot 3a is corresponded with the position of all accommodating structures in the circumferential.
The immunity analysis instrument further includes loading component 4 and detection components 6, and loading component 4, which includes at least, is slidably set to machine
It can stretch on shell 1 and up and down discharged from sampling in sample cell and by sample to the loading needle 41 on corresponding detection strip, inspection
It surveys component 6 and analysis is detected to detection strip again after preset time after detection strip is released sample, gone back on casing 1
Output precision equipped with the testing result for accordingly exporting detection components 6.In this way, being revolved by rotary sample disk 2 and strip
The automatic rotary of turntable 3, which transfers, to be realized sample cell and detects automatically delivering for strip, then is sampled from sample cell by loading component 4
And discharge sample to corresponding detection strip, it is detected by detection components 6 after preset time, then by output precision
Corresponding testing result is automatically exported, realizes automatic sample detection.
Shown in Fig. 1, Fig. 2, in the present embodiment, strip rotating disk 3 is fixedly superimposed upon the upper end of rotary sample disk 2,
The two coaxial inner conductor is arranged, and strip rotating disk 3 is synchronously rotated with rotary sample disk 2 around same shaft 8, and rotating driving device is adopted
With rotation motor, be set to the lower section of rotary sample disk 2, the rotation motor drive shaft 8 to rotate and make rotary sample disk 2 with
Strip rotating disk 3 is synchronously rotated by some direction.
On rotary sample disk 2, accommodating structure is the storage tank being opened in 2 circumferential sides of rotary sample disk in half column shape
2a, single sample cell can be ordinatedly fastened in storage tank 2a, not only be conducive to place sample cell in this way, it is also possible that sample
Label information in quality control is exposed and facilitates identification.The diameter of strip rotating disk 3 makes card less than the diameter of rotary sample disk 2
The circumferential edge of rotating disk 3 is located at the inside of storage tank 2a, to avoid strip rotating disk 3 from blocking the nozzle of sample cell.
In the present embodiment, all card slot 3a are circumferentially evenly spaced apart to be distributed in strip rotating disk 3, all appearances
It sets slot 2a to be also circumferentially evenly spaced apart to be distributed in the circumferential direction of rotary sample disk 2, all card slot 3a and all storage tanks
The position of 2a corresponds.Specifically, shown in Figure 3, in the present embodiment, strip rotating disk 3 is circumferentially equably divided
At 12 identical sector regions, it is respectively provided with that there are one card slot 3a, each card slot 3a accordingly to use in each sector region
In the one or a set of detection strip of placement；Accordingly, referring to shown in Fig. 1, Fig. 2, rotary sample disk 2 is circumferentially also divided into 12
Sector region, is all provided with that there are one storage tank 2a to place a sample cell in each sector region.On rotary sample disk 2 this 12
The angle of a sector region is mutually corresponded with 12 sector regions in strip rotating disk 3.In this way, each group of sector region
Interior, a sample cell corresponds to one or a set of detection strip.
In the present embodiment, the projection edge of the center line of each storage tank 2a and corresponding card slot 3a in the horizontal plane
Same rectilinear direction extends and perpendicular to the axial line of shaft 8, in this way, loading needle 41 is along being parallel to rotary sample disk 2 or strip
The radial direction translation of rotating disk 3 can be realized from sampling in sample cell and discharge sample to corresponding detection strip
.
Rotary sample disk 2 can be by stainless steel, plastics, resin or other wear-resistant resistant materials with strip rotating disk 3
It is made, quick detachable cleaning.Wherein, strip rotating disk 3 is removable installed on rotary sample disk 2, can be according to detection strip
Practical structures come select installation with different card slot 3a strip rotating disk 3.It can be pressed on strip rotating disk 3 and rotary sample disk 2
Each sector region is numbered in the mode of Fig. 3, so as to easily carry out control operation according to sample region.
Shown in Fig. 1, Fig. 2 and Fig. 4, on loading component 4, loading needle 41 include needle holder 41a, can be in needle holder 41a on
Flexible syringe needle 41b down, and syringe needle 41b is detachably arranged on needle holder 41b in order to replace and deep clean.On needle holder 41a
It is also associated with level sensor 42 and sampling is realized with the collapsing length for controlling syringe needle 41b, which is that can pass through
The change of air pressure change, color change or other modes reaches the sensing device for judging liquid level, to incude the sample in sample cell
Liquid level so that syringe needle 41b accordingly stretches into sampling below liquid level.Casing 1 is equipped with sliding rail 9, the length direction and sample of the sliding rail 9
The radial direction of product rotating disk 2 and strip rotating disk 3 is parallel, and needle holder 41a is slidably set on sliding rail 9 to realize from sample cell
Top switches with the position above detection strip.
Loading needle assemblies 4 further include buffer solution component for providing loading needle buffer solution and for being carried out to loading needle 41
The cleaning assembly of cleaning, the waste liquid component for collecting waste liquid, buffer solution component include buffer solution bottle 43 and slow for connecting
The connecting pipeline of fliud flushing bottle 43 and loading needle 41；Cleaning assembly includes cleaning solution bottle 44 and for connecting cleaning solution bottle 44 and loading
The connecting pipeline of needle 41；Waste liquid component includes waste liquid bottle 45.Cleaning solution bottle 44 can be one or more, can be according to actual needs
Different types of cleaning solution is preserved, to be cleaned to loading needle 41 after a completion of the sample, avoids cross contamination.
The immunity analysis instrument further includes the sample recognizer component 5 of sample message on rotary sample disk 2 for identification, through sample
The sample that recognizer component 5 is identified into row information is corresponded to by output precision after through 4 loading of loading component and after testing, component 6 detects
Ground exports testing result.In the present embodiment, sample recognizer component 6 is the scanning mould for reading label information on sample cell
Block, the scan module are set to the side on casing 1 and positioned at rotary sample disk 2.For convenience of sampling operation, loading component 4 is set to
The rear of sample recognizer component 5, in this way, when the rotation of rotary sample disk 2 to sample cell to be detected reaches at above-mentioned scan module
When, scan module scans and recognizes the label information on the outside of sample cell；Wait for the sample cell rotating to rotary sample disk 2
Up to loading component 4 underface when, loading needle 41 in sample cell from sampling and discharge to corresponding detection strip；Wait for that sample revolves
When turntable 2 is rotated with strip rotating disk 3 to the position of detection components 6, detection components 6 examine the result of the detection strip
Analysis is surveyed, and accordingly feeds back to output precision and is exported.
Herein, detection components 6 are set to 3 top of strip rotating disk, are divided into colloid gold immune detection module and fluorescence immunoassay
Detection module is analyzed, can be exchanged according to different detection patterns, its operating condition is controlled by program software.When setting, answer
Same detection strip is set as the set time by the time that loading position is rotated to inspection positions, which should make
The sample that must be discharged on detection strip completes chromatography process, in this way, when detection strip is rotated to detection module, if
It is standby to initially enter detection pattern.
Shown in Figure 1, casing 1 is the babinet with side door 1a, rotary sample disk 2, strip rotating disk 3 and loading component
4, sample recognizer component 5, detection components 6 are set in the babinet, and sample cell and detection card can accordingly be placed by opening side door 1a
Item.Output precision includes the display screen 7 for being set to 1 top of casing, and it is any other which can also be installed on casing 1 certainly
On surface, may be configured as it is foldable, can touch screen, various sizes of display screen, which can be by liquid crystal, quantum dot
Or other methods that can be made into display screen and material are made.The power interface for connecting power supply is additionally provided on casing 1.
The analyzer further includes the control for controlling the component workings states such as rotation motor, loading component 4, detection components 6
Device processed, the controller can be mounted on 1 inside of casing and carry out operation operation by the touch control on display screen 7.The controller
Printer can be connected, reports and prints out to form testing result.
The course of work of the immunity analysis instrument of lower the present embodiment is illustrated in detail below：
（1）Power on, start analyzer equipment, equipment enters Auto-Sensing Mode；
（2）To avoid equipment kinematic error, equipment live can be allowed to preheat 10-30min before sample detection；
（3）Before sample detection, whether normal sample is first observed, if it is enough, such as obviously there is haemolysis, piarhemia or jaundice
Sample, sample can be reprocessed or be resampled；Under the premise of determining that sample is normal, sample cell is placed in sample rotation
In the storage tank 2a of turntable 2, and make the label information on sample cell towards outside；Detection strip is placed in strip rotating disk
On 3 in card slot 3a corresponding with above-mentioned storage tank 2a；
（4）It is compiled in the storage tank 2a of display screen 7 touched at control in input sample rotating disk 2 where detected sample pipe
Number, operation is clicked, rotation motor drives rotary sample disk 2 synchronously to be rotated at same direction with strip rotating disk 3；
（5）When sample cell to be detected is rotated to sample recognizer component 5, scan module starts to scan sample message,
And feed back to controller；Controller accordingly provides instruction to loading component 4；When sample cell to be detected is rotated to loading component
When 4 lower section, loading needle 41 is first slided to sample cell, and syringe needle 41b extends downwards, 42 synchronous averaging of level sensor,
When level sensor 42 senses liquid level, loading needle 41 starts to sample by preset vol.After the completion of sampling, syringe needle 41b is in needle
It is shunk upwards in support 41a, loading needle 41 is slided along sliding rail 9 to the top of detection strip sample well, and loading needle 41 starts to discharge sample
Product, while the quantitative buffer solution of suck-back is discharged at sample well as needed；
（6）Sample starts to chromatograph on detection strip, and loading needle 41 is retracted into 43 top of cleaning solution bottle and starts to execute cleaning
Program, after to be cleaned, loading needle 41 is retracted into initial position；In this process,
Rotary sample disk 2 continues to rotate with strip rotating disk 3, by regular time, that is, waits for sample on detection strip
After the completion of chromatography, detection strip just rotates to the underface of detection components 6, starts to detect；
（7）After the completion of detection, result is automatically fed back to output precision and is shown on display screen 7 by detection components 6, most
After print report, terminate this detection program.System will automatically enter next round according to the time difference for placing sample cell
Detection operation.
To sum up, the full-automatic sample detection immunity analysis instrument of strip formula of the invention can carry out colloid gold immune quantitative analysis
With fluorescence immunoassay quantitative analysis, wherein only by two be superimposed rotating disk and a rotation motor can realize sample cell with inspection
The transmission for surveying strip, can effectively place the occupied plane domain of sample cell and detection reagent pond that conventional instrument is equipped with
It is placed in a small-sized desk-top casing in a hierarchical space, space structure is compact, is convenient for carrying, installs, operates.Together
When, rotary sample disk 2 is continuously shifted with strip rotating disk 3 in limited border circular areas, is avoided and is equipped with large complicated biography
Sending component and manipulator can reduce equipment and take up space and equipment operation energy consumption, while also be greatly reduced as much as possible
Cost.The immunity analysis instrument realizes automatic loading and automatic detection, the error for avoiding manual operation from bringing, and can realize single
The purpose that pattern detection and small lot continuously detect, simple in structure, small volume, energy saving space more save cost.
The above embodiments merely illustrate the technical concept and features of the present invention, and its object is to allow person skilled in the art
Scholar can understand present disclosure and be implemented, and it is not intended to limit the scope of the present invention, all according to the present invention
Equivalent change or modification made by Spirit Essence should all cover within the scope of the present invention.
Claims (9)
1. a kind of full-automatic sample detection immunity analysis instrument of strip formula, it is characterised in that：The immunity analysis instrument includes casing
（1）, can around Pivot Point Center line rotatably be set to the casing（1）On rotary sample disk（2）With strip rotating disk（3）, be used for
Drive the rotary sample disk（2）With strip rotating disk（3）The rotating driving device of rotation, wherein the strip rotating disk（3）
Fixedly it is superimposed upon the rotary sample disk（2）Upper end, and the strip rotating disk（3）With the rotary sample disk（2）Around
Shaft（8）It synchronously rotates, the rotary sample disk（2）Circumferential sides on compartment of terrain be equipped with it is multiple be used for fixed placement sample
The accommodating structure of pipe, the strip rotating disk（3）Upper surface be equipped with it is multiple for place it is one or a set of detection strip cards
Slot（3a）, all card slot（3a）In the strip rotating disk（3）Upper circumferentially spaced, the card slot（3a）
The number card slot consistent and all with the number of the accommodating structure（3a）In the circumferential with all accommodating structures
Position correspond, the strip rotating disk（3）Diameter be less than the rotary sample disk（2）Diameter and make the card
Rotating disk（3）Circumferential edge be located at the inside of the accommodating structure,
The immunity analysis instrument further includes loading component（4）And detection components（6）, the loading component（4）Including at least sliding
Ground is set to the casing（1）It can stretch above and up and down to be sampled from the sample cell and discharge sample to corresponding detection card
Loading needle on item（41）, the detection components（6）By preset time again to this after the detection strip is released sample
Detection strip is detected analysis, the casing（1）On be additionally provided with for accordingly exporting the detection components（6）Detection knot
The output precision of fruit.
2. immunity analysis instrument according to claim 1, it is characterised in that：The accommodating structure is to be opened in the sample rotation
Turntable（2）It is in the storage tank of half column shape in circumferential sides（2a）, the single sample cell can ordinatedly be fastened on the appearance
Set slot（2a）In, the strip rotating disk（3）Circumferential edge be located at the storage tank（2a）Inside.
3. immunity analysis instrument according to claim 2, it is characterised in that：All card slots（3a）It is revolved in the strip
Turntable（3）On be circumferentially evenly spaced apart to be distributed, all accommodating structures are in the rotary sample disk（2）Outside circumference
On be evenly spaced apart to be distributed, all card slots（3a）It is corresponded with all accommodating structures.
4. immunity analysis instrument according to claim 2, it is characterised in that：Each storage tank（2a）With it is corresponding
The card slot（3a）Center line projection in the horizontal plane extend along same rectilinear direction and perpendicular to the shaft（8）Axis
Heart line, the loading needle（41）Along the rotary sample disk（2）Or the strip rotating disk（3）Radial direction translation realize take
Sample and release sample.
5. immunity analysis instrument according to claim 1, it is characterised in that：The immunity analysis instrument further includes institute for identification
State rotary sample disk（2）The sample recognizer component of upper sample message（5）, through the sample recognizer component（5）It is identified into row information
Sample again through the loading component（4）Loading and the detection components（6）After detection, output inspection is corresponded to by the output precision
Survey result.
6. immunity analysis instrument according to claim 5, it is characterised in that：The sample recognizer component（5）To be used to read
The scan module of label information on the sample cell, the scan module are set to the casing（1）It goes up and is located at the sample rotation
Turntable（2）Side.
7. immunity analysis instrument according to claim 1, it is characterised in that：The detection components（6）To be set to the strip
Rotating disk（3）Top colloid gold immune detection module or fluoroimmunoassay detection module.
8. immunity analysis instrument according to claim 1, it is characterised in that：The loading needle（41）Including needle holder（41a）, can
In the needle holder（41a）The interior syringe needle to stretch up and down（41b）, the needle holder（41a）On be additionally provided with level sensor（42）With control
Make the syringe needle（41b）Collapsing length and realize sampling, the loading component（4）Further include for providing the loading needle
（41）The Buffer Unit of buffer solution and for the loading needle（41）The cleaning assembly cleaned.
9. immunity analysis instrument according to claim 1, it is characterised in that：The casing（1）For with side door（1a）Case
Body, the rotary sample disk（2）, strip rotating disk（3）And loading component（4）It is set in the babinet, the output precision
It include the display screen set on the top of the box（7）.
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| CN106855515B (en) * | 2017-01-22 | 2023-11-24 | 武汉璟泓科技股份有限公司 | Colloidal gold fluorescence quantitative analysis all-in-one machine and its control method |
| CN107446808B (en) * | 2017-08-23 | 2023-09-29 | 成都万众壹芯生物科技有限公司 | Gene sequencer |
| CN107843580A (en) * | 2017-12-06 | 2018-03-27 | 苏州市苏测检测技术有限公司 | On-line monitoring formula food inspection device |
| CN108181302A (en) * | 2017-12-21 | 2018-06-19 | 西安交通大学 | A kind of water quality safety detection device and water quality detection method |
| CN109444450B (en) * | 2018-12-27 | 2022-05-17 | 厦门先明生物技术有限公司 | Whole blood sample autoinjection device |
| CN110275020A (en) * | 2019-08-01 | 2019-09-24 | 郑州迈迪迅医疗科技有限公司 | A rotary chromatography detection device |
| CN117723743B (en) * | 2023-12-18 | 2025-01-21 | 浙江华芯云生物科技有限公司 | Fully automatic reaction waiting mechanism and use method of immunochromatographic test card |
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