CN105779177A - Traditional Chinese medicine antibacterial soap and preparation method thereof - Google Patents
Traditional Chinese medicine antibacterial soap and preparation method thereof Download PDFInfo
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- CN105779177A CN105779177A CN201610126216.1A CN201610126216A CN105779177A CN 105779177 A CN105779177 A CN 105779177A CN 201610126216 A CN201610126216 A CN 201610126216A CN 105779177 A CN105779177 A CN 105779177A
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- chinese medicine
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- acid sodium
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- 239000003814 drug Substances 0.000 title claims abstract description 82
- 239000000344 soap Substances 0.000 title claims abstract description 69
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- 230000000844 anti-bacterial effect Effects 0.000 title abstract description 22
- 239000002994 raw material Substances 0.000 claims abstract description 64
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 39
- 239000000194 fatty acid Substances 0.000 claims abstract description 39
- 229930195729 fatty acid Natural products 0.000 claims abstract description 39
- 241000628997 Flos Species 0.000 claims abstract description 38
- 239000007788 liquid Substances 0.000 claims abstract description 37
- 239000011734 sodium Substances 0.000 claims abstract description 27
- 229910052708 sodium Inorganic materials 0.000 claims abstract description 27
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 19
- -1 sodium fatty acid Chemical class 0.000 claims abstract description 14
- 238000002156 mixing Methods 0.000 claims abstract description 12
- 230000001954 sterilising effect Effects 0.000 claims description 50
- 239000000706 filtrate Substances 0.000 claims description 33
- 239000004615 ingredient Substances 0.000 claims description 31
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 28
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 25
- 150000004665 fatty acids Chemical class 0.000 claims description 25
- 239000002893 slag Substances 0.000 claims description 22
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- 239000000835 fiber Substances 0.000 claims description 17
- 238000003756 stirring Methods 0.000 claims description 13
- 239000012467 final product Substances 0.000 claims description 11
- 238000000227 grinding Methods 0.000 claims description 11
- 230000007935 neutral effect Effects 0.000 claims description 11
- 239000003240 coconut oil Substances 0.000 claims description 10
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- 235000019482 Palm oil Nutrition 0.000 claims description 8
- 239000002540 palm oil Substances 0.000 claims description 8
- 244000068988 Glycine max Species 0.000 claims description 6
- 235000010469 Glycine max Nutrition 0.000 claims description 6
- 230000000694 effects Effects 0.000 abstract description 11
- 238000004140 cleaning Methods 0.000 abstract description 3
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract description 2
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract description 2
- 235000013399 edible fruits Nutrition 0.000 abstract description 2
- 239000003053 toxin Substances 0.000 abstract description 2
- 231100000765 toxin Toxicity 0.000 abstract description 2
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- 239000000243 solution Substances 0.000 description 28
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 9
- 241000588724 Escherichia coli Species 0.000 description 8
- 230000002159 abnormal effect Effects 0.000 description 8
- 229940023064 escherichia coli Drugs 0.000 description 8
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- 239000002609 medium Substances 0.000 description 7
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
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- FFRBMBIXVSCUFS-UHFFFAOYSA-N 2,4-dinitro-1-naphthol Chemical compound C1=CC=C2C(O)=C([N+]([O-])=O)C=C([N+]([O-])=O)C2=C1 FFRBMBIXVSCUFS-UHFFFAOYSA-N 0.000 description 2
- 241001478240 Coccus Species 0.000 description 2
- 208000003351 Melanosis Diseases 0.000 description 2
- ZYEMGPIYFIJGTP-UHFFFAOYSA-N O-methyleugenol Chemical compound COC1=CC=C(CC=C)C=C1OC ZYEMGPIYFIJGTP-UHFFFAOYSA-N 0.000 description 2
- 239000001888 Peptone Substances 0.000 description 2
- 108010080698 Peptones Proteins 0.000 description 2
- 241000588769 Proteus <enterobacteria> Species 0.000 description 2
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 2
- 241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 description 2
- 206010040849 Skin fissures Diseases 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- 241000194017 Streptococcus Species 0.000 description 2
- 241000193998 Streptococcus pneumoniae Species 0.000 description 2
- 241000607626 Vibrio cholerae Species 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 229940041514 candida albicans extract Drugs 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
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- 239000000463 material Substances 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 235000019319 peptone Nutrition 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 150000008130 triterpenoid saponins Chemical class 0.000 description 2
- 239000012138 yeast extract Substances 0.000 description 2
- RDEIXVOBVLKYNT-VQBXQJRRSA-N (2r,3r,4r,5r)-2-[(1s,2s,3r,4s,6r)-4,6-diamino-3-[(2r,3r,6s)-3-amino-6-(1-aminoethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol;(2r,3r,4r,5r)-2-[(1s,2s,3r,4s,6r)-4,6-diamino-3-[(2r,3r,6s)-3-amino-6-(aminomethyl)oxan-2-yl]o Chemical compound OS(O)(=O)=O.O1C[C@@](O)(C)[C@H](NC)[C@@H](O)[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H](CC[C@@H](CN)O2)N)[C@@H](N)C[C@H]1N.O1C[C@@](O)(C)[C@H](NC)[C@@H](O)[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H](CC[C@H](O2)C(C)N)N)[C@@H](N)C[C@H]1N.O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N RDEIXVOBVLKYNT-VQBXQJRRSA-N 0.000 description 1
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 description 1
- 239000001169 1-methyl-4-propan-2-ylcyclohexa-1,4-diene Substances 0.000 description 1
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- 244000063299 Bacillus subtilis Species 0.000 description 1
- 235000014469 Bacillus subtilis Nutrition 0.000 description 1
- 241001116415 Balanophora Species 0.000 description 1
- ZKQDCIXGCQPQNV-UHFFFAOYSA-N Calcium hypochlorite Chemical compound [Ca+2].Cl[O-].Cl[O-] ZKQDCIXGCQPQNV-UHFFFAOYSA-N 0.000 description 1
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 description 1
- 206010008570 Chloasma Diseases 0.000 description 1
- 239000005770 Eugenol Substances 0.000 description 1
- 241000192125 Firmicutes Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 241001278898 Glycyrrhiza inflata Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241000218195 Lauraceae Species 0.000 description 1
- 240000007872 Melica scabrosa Species 0.000 description 1
- 235000008899 Melica scabrosa Nutrition 0.000 description 1
- 241000187479 Mycobacterium tuberculosis Species 0.000 description 1
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 description 1
- 241000531795 Salmonella enterica subsp. enterica serovar Paratyphi A Species 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 241000191940 Staphylococcus Species 0.000 description 1
- 208000037386 Typhoid Diseases 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 230000002155 anti-virotic effect Effects 0.000 description 1
- 239000012984 antibiotic solution Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 239000010231 banlangen Substances 0.000 description 1
- FCPVYOBCFFNJFS-LQDWTQKMSA-M benzylpenicillin sodium Chemical compound [Na+].N([C@H]1[C@H]2SC([C@@H](N2C1=O)C([O-])=O)(C)C)C(=O)CC1=CC=CC=C1 FCPVYOBCFFNJFS-LQDWTQKMSA-M 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000007844 bleaching agent Substances 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 239000010238 camphora Substances 0.000 description 1
- 229940025250 camphora Drugs 0.000 description 1
- 239000003518 caustics Substances 0.000 description 1
- 210000003756 cervix mucus Anatomy 0.000 description 1
- 239000012459 cleaning agent Substances 0.000 description 1
- 239000013068 control sample Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 241001233957 eudicotyledons Species 0.000 description 1
- 229960002217 eugenol Drugs 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000002070 germicidal effect Effects 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 229940116837 methyleugenol Drugs 0.000 description 1
- PRHTXAOWJQTLBO-UHFFFAOYSA-N methyleugenol Natural products COC1=CC=C(C(C)=C)C=C1OC PRHTXAOWJQTLBO-UHFFFAOYSA-N 0.000 description 1
- 238000009629 microbiological culture Methods 0.000 description 1
- 239000013642 negative control Substances 0.000 description 1
- 235000014593 oils and fats Nutrition 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 150000007875 phellandrene derivatives Chemical class 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 238000007127 saponification reaction Methods 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 description 1
- 229940031000 streptococcus pneumoniae Drugs 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 229920001864 tannin Polymers 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 206010046901 vaginal discharge Diseases 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D10/00—Compositions of detergents, not provided for by one single preceding group
- C11D10/04—Compositions of detergents, not provided for by one single preceding group based on mixtures of surface-active non-soap compounds and soap
- C11D10/045—Compositions of detergents, not provided for by one single preceding group based on mixtures of surface-active non-soap compounds and soap based on non-ionic surface-active compounds and soap
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/02—Compositions of detergents based essentially on soap on alkali or ammonium soaps
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/04—Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
- C11D9/22—Organic compounds, e.g. vitamins
- C11D9/38—Products in which the composition is not well defined
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/662—Carbohydrates or derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Detergent Compositions (AREA)
Abstract
The invention belongs to the technical field of cleaning supplies, and particularly relates to traditional Chinese medicine antibacterial soap and a preparation method thereof.The soap is prepared from traditional Chinese medicine components and sodium fatty acid.The traditional Chinese medicine components include, by weight, 12-19 parts of flos lonicerae, 16-22 parts of radix scutellariae, 10-15 parts of cortex cinnamomi, 18-25 parts of cortex moutan, 8-15 parts of folium artemisiae argyi, 15-25 parts of Flos Caryophylli, 10-15 parts of radix angelicae dahuricae, 5-10 parts of Borneolum Syntheticum, 4-10 parts of Chinese Honeylocust Fruit and 16-23 parts of licorice root.The product traditional Chinese medicine antibacterial soap is obtained by mixing concentration liquid obtained by decocting the raw materials with sodium fatty acid with a dirt removing effect.The soap is good in dirt removal effect and antibacterial effect, fresh in smell, capable of nourishing skin and free of toxin and harms.
Description
Technical field
The invention belongs to cleaning supplies technical field, be specifically related to a kind of Chinese medicine sterilizing soap and preparation method thereof.
Background technology
Soap is the general name of fatty acid metal salts, can be dissolved in water, has washing decontamination, and wherein soap is generated by saponification by various oils and fatss and aqueous slkali.Current soap kind is varied, deterging white effect is relatively good, but the removal of bacteria DeGrain on medicated clothing, and Conventional soaps contains the material that human body skin is harmful: such as bleaching powder, hydrargyrum, cleaning agent, caustic etc., therefore, exploitation has decontamination and bacteria-eliminating efficacy, and the soap of human body fanout free region is had great importance.
Chinese patent CN10270323A discloses a kind of degerming soap of natural plant, mainly produce concentrated solution for primary raw material mix with Radix Isatidis, Rhizoma Zingiberis Recens, Radix Scutellariae, Herba Houttuyniae, Herba Taraxaci, Flos Lonicerae, Pericarpium Zanthoxyli with a certain proportion of cleaning, decontamination composition, make decontamination can also have the health care soap of antiviral, sterilization through modernization process.But, the soap sterilizing ability of this patent is low, and Chinese medicine ingredients flavour of a drug are strong, inadequate delicate fragrance.
Chinese patent CN103666890B discloses a kind of Traditional Chinese medicinal liquid soap, is made up of sodium lauryl sulfate 40-60 part, lanoline 6-10 part, Balanophora dioica R Br ex Royle 2-4 part, Melica scabrosa Trin. 2-4 part, and this Traditional Chinese medicinal liquid soap has good foaming and antibacterial effect.But this patent soap is liquid form, in-convenience in use, antibacterial effect is inconspicuous.
Summary of the invention
For overcoming drawbacks described above, it is an object of the invention to provide a kind of Chinese medicine sterilizing soap, not only decontamination and bactericidal effect are good, and abnormal smells from the patient is pure and fresh, nourishes rough skin, nontoxic.
Another object of the present invention also resides in the preparation method providing a kind of Chinese medicine sterilizing soap.
For achieving the above object, the present invention adopts the following technical scheme that
A kind of Chinese medicine sterilizing soap, including Chinese medicine ingredients and fatty acid sodium salt, described Chinese medicine ingredients is made up of the raw material of following parts by weight:
Flos Lonicerae 12～19 parts, Radix Scutellariae 16～22 parts, Cortex Cinnamomi 10～15 parts, Cortex Moutan 18～25 parts, Folium Artemisiae Argyi 8～15 parts, Flos Caryophylli 15～25 parts, the Radix Angelicae Dahuricae 10～15 parts, Borneolum Syntheticum 5～10 parts, 4～10 parts of Fructus Gleditsia and 16～23 parts of Radix Glycyrrhizae.
According to above-mentioned Chinese medicine sterilizing soap, described Chinese medicine ingredients is made up of the raw material of following parts by weight:
Flos Lonicerae 13～15 parts, Radix Scutellariae 18～20 parts, Cortex Cinnamomi 11～15 parts, Cortex Moutan 18～20 parts, Folium Artemisiae Argyi 10～12 parts, Flos Caryophylli 16～20 parts, the Radix Angelicae Dahuricae 10～12 parts, Borneolum Syntheticum 6～9 parts, 5～8 parts of Fructus Gleditsia and 17～20 parts of Radix Glycyrrhizae.
According to above-mentioned Chinese medicine sterilizing soap, described Chinese medicine ingredients is made up of the raw material of following parts by weight:
Flos Lonicerae 14 parts, Radix Scutellariae 19 parts, Cortex Cinnamomi 13 parts, Cortex Moutan 19 parts, Folium Artemisiae Argyi 11 parts, Flos Caryophylli 16 parts, the Radix Angelicae Dahuricae 11 parts, Borneolum Syntheticum 8 parts, 6 parts of Fructus Gleditsia and 18 parts of Radix Glycyrrhizae.
According to above-mentioned Chinese medicine sterilizing soap, described Chinese medicine ingredients and the weight ratio of fatty acid sodium salt are 1:0.6～1.1.
According to above-mentioned Chinese medicine sterilizing soap, described fatty acid sodium salt is coco-nut oil fatty acid sodium, palm oil fatty acid sodium or soya fatty acid sodium.
According to above-mentioned Chinese medicine sterilizing soap, also including Plant fiber, the weight ratio of Chinese medicine ingredients, fatty acid sodium salt and Plant fiber is 1:0.6～1.1:0.01.
According to above-mentioned Chinese medicine sterilizing soap, described plant fiber length 400～600 μm, diameter 10～50nm.
The preparation method of a kind of Chinese medicine sterilizing soap, it is characterised in that comprise the following steps:
(1) raw material of each parts by weight is cleaned up, dry, broken；
(2) each raw material mixing after step (1) being crushed, adds 5～10 times amount water, decocts 2～3 times, each 20～40min, take decocting liquid, collect raw material slag；
(3) the raw material slag in step (2) is added 5～7 times amount water, continue decoction 2～3 times, each 20～40min, take decocting liquid；
(4) combining step (2) and (3) decocting liquid, 40～80 orders filter, and obtain filtrate, filtrate are carried out cryogenic vacuum and is concentrated into the 1/3～1/2 of filtrate volume, obtain concentrated solution；
(5) step (4) concentrated solution is heated to 70～80 DEG C, add fatty acid sodium salt, or add fatty acid sodium salt and Plant fiber, stir melt and dissolved 20～50min, adjust pH value to neutral, be then cooled to 30～45 DEG C, keep 3～4h, grinding tool is cooled to bulk, to obtain final product.
The pharmacological action of each raw material of the present invention: Flos Lonicerae, cold in nature, sweet in the mouth, enter lung, the heart, stomach warp, external is inhibited to golden yellow glucose coccus, Hemolytic streptococcus, dysentery bacterium, Bacillus typhi, meningococcus, Diplococcus pneumoniae.
Radix Scutellariae, returns liver, spleen, lung, kidney channel, and external has broad-spectrum antibacterial action, it is possible to eliminating toxin and beautifying the skin, evacuation of pus granulation promoting, remove black vaginal discharge, acne effect.
Cortex Cinnamomi, pungent, sweet, hot greatly, return kidney, spleen, the heart, Liver Channel, for dried bark and the thick branch skin of Lauraceae aiphyllium plant Cortex Cinnamomi, containing phellandrene, eugenol, methyleugenol etc., can sterilize, antibacterial, pre-preventing germs infection.
Cortex Moutan, bitter, pungent, it is slightly cold, GUIXIN, liver, kidney channel, experiment in vitro shows, bacillus subtilis, escherichia coli, Bacillus typhi, Salmonella paratyphi, Bacillus proteus, bacillus pyocyaneus, staphylococcus, Hemolytic streptococcus, streptococcus pneumoniae, vibrio cholera etc. are all had stronger antibacterial action by Cortex Moutan decoct.
Folium Artemisiae Argyi, pungent, bitter, temperature, return liver,spleen,kidney warp, have a peat-reek, external dredge the meridian passage, dispelling cold and removing dampness, antipruritic, there is antibacterial and antivirus action, various bacteria and fungus is inhibited.
Flos Caryophylli, pungent, temperature, return spleen, stomach, lung, kidney channel, abnormal smells from the patient is simple and elegant, fragrant, has anti-inflammation, antiviral, antioxidative effect.
The Radix Angelicae Dahuricae, pungent, temperature, return stomach, large intestine, lung meridian, escherichia coli, Song Shi and bacterium flexneri, Bacillus proteus, Typhoid and paratyphoid bacillus, bacillus pyocyaneus, vibrio cholera, some gram-positive bacteria and Bacillus tuberculosis etc. are had inhibitory action in various degree by the Radix Angelicae Dahuricae in vitro, and Shennong's Herbal claims Radix Angelicae Dahuricae external to have the effect of longue skin, moist skin, " Japan hanako materia medica " thinks that Radix Angelicae Dahuricae external relieves the pain granulation promoting, goes the effects such as face speckle.
Borneolum Syntheticum, pungent, bitter, cool, abnormal smells from the patient delicate fragrance, similar Camphora abnormal smells from the patient, external can skin whitening, moist skin, slow down the moisture loss of skin, also there is antibacterial, antiinflammatory action.
Fructus Gleditsia, pungent, salty, temperature, return lung, large intestine channel, for the dry fruit of pulse family Gleditsia plant Fructus Gleditsia, containing triterpenoid saponin, tannin, it is possible to antibacterial, antiviral, there is the effect of emulsifying, foaming, steady bubble.
Radix Glycyrrhizae, sweet, flat, GUIXIN, lung, spleen, stomach warp, Radix Glycyrrhizae is the root and rhizome of dicotyledon pulse family Radix Glycyrrhizae, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L., main containing triterpenoid saponin, it is possible to antibacterial, antiviral, has the effect of emulsifying, foaming.
Raw material pure natural in Chinese medicine sterilizing soap formulation of the present invention, without any additive, nontoxic, various raw materials coordinate rationally precise and appropriate, and Flos Lonicerae, Radix Scutellariae and Cortex Cinnamomi compatibility use, and have antiviral, bactericidal action, it is suppressed that growing of medicated clothing antibacterial；Cortex Moutan, Folium Artemisiae Argyi and Flos Caryophylli combine and use, and abnormal smells from the patient is pure and fresh, further enhances bactericidal effect；Adding the use of the Radix Angelicae Dahuricae, Borneolum Syntheticum, skin care again, moistening effect is good, after overcoming conventional soap mistake, and the problem of chapped skin, decrease the soap injury to human body skin；Fructus Gleditsia, Radix Glycyrrhizae also have the effect of emulsifying, foaming, improve the dirt-removing power of soap, and the abnormal smells from the patient delicate fragrance of Folium Artemisiae Argyi, Flos Caryophylli and Borneolum Syntheticum, simple and elegant, and the medicated clothing after making washing keeps light fragrance.Above-mentioned various material combinations use, and further add the fatty acid sodium salt of decontamination, and germicidal soaps decontamination of the present invention and bactericidal effect are good, and abnormal smells from the patient is pure and fresh, nourishes rough skin.
The positive beneficial effect of the present invention
1. Chinese medicine sterilizing soap of the present invention not only achieves the function removing dirt of soap, and dirt-removing power is strong, and has possessed good sterilization and sterilizing function, to staphylococcus aureus (Staphlococcusaureus) and escherichia coli (Escherichiacoli) there is good inhibiting effect.
2., after Chinese medicine sterilizing soap of the present invention washing medicated clothing, medicated clothing abnormal smells from the patient is pure and fresh, after also overcoming conventional soap mistake, and the problem of chapped skin, decrease the soap injury to human body skin, staff sensation is moistening, comfortable, moist.
3. Plant fiber of the present invention be added with the combination being beneficial to antibacterial, improve the clearance of antibacterial, additionally Plant fiber and sodium soap salt binding, make laundry rinse quick, saving water resource.
Detailed description of the invention
Below in conjunction with some detailed description of the invention, the present invention is further described.
Embodiment 1
A kind of Chinese medicine sterilizing soap, including the Chinese medicine ingredients that weight ratio is 1:1.1 and coco-nut oil fatty acid sodium, Chinese medicine ingredients is made up of the raw material of following parts by weight:
Flos Lonicerae 12 parts, Radix Scutellariae 16 parts, Cortex Cinnamomi 10 parts, Cortex Moutan 18 parts, Folium Artemisiae Argyi 8 parts, Flos Caryophylli 15 parts, the Radix Angelicae Dahuricae 10 parts, Borneolum Syntheticum 5 parts, 4 parts of Fructus Gleditsia and 16 parts of Radix Glycyrrhizae.
The preparation method of above-mentioned Chinese medicine sterilizing soap, comprises the following steps:
(1) raw material of above-mentioned each parts by weight is cleaned up, dry, broken；
(2) each raw material mixing after step (1) being crushed, adds 5 times amount water, decocts 3 times, each 30min, take decocting liquid, collect raw material slag；
(3) the raw material slag in step (2) is added 6 times amount water, continue to decoct 2 times, each 20min, take decocting liquid；
(4) combining step (2) and (3) decocting liquid, 40 orders filter, and obtain filtrate, filtrate are carried out cryogenic vacuum and is concentrated into the 1/3 of filtrate volume, obtain concentrated solution；
(5) step (4) concentrated solution is heated to 70 DEG C, add coco-nut oil fatty acid sodium, stir melt and dissolved 40min, adjust pH value to neutral, be then cooled to 45 DEG C, keep 3h, grinding tool is cooled to bulk, to obtain final product.
Embodiment 2
A kind of Chinese medicine sterilizing soap, including the Chinese medicine ingredients that weight ratio is 1:1.0 and coco-nut oil fatty acid sodium, Chinese medicine ingredients is made up of the raw material of following parts by weight:
Flos Lonicerae 13 parts, Radix Scutellariae 18 parts, Cortex Cinnamomi 11 parts, Cortex Moutan 18 parts, Folium Artemisiae Argyi 10 parts, Flos Caryophylli 16 parts, the Radix Angelicae Dahuricae 10 parts, Borneolum Syntheticum 6 parts, 5 parts of Fructus Gleditsia and 17 parts of Radix Glycyrrhizae.
The preparation method of above-mentioned Chinese medicine sterilizing soap, comprises the following steps:
(1) raw material of above-mentioned each parts by weight is cleaned up, dry, broken；
(2) each raw material mixing after step (1) being crushed, adds 6 times amount water, decocts 2 times, each 20min, take decocting liquid, collect raw material slag；
(3) the raw material slag in step (2) is added 5 times amount water, continue to decoct 3 times, each 30min, take decocting liquid；
(4) combining step (2) and (3) decocting liquid, 70 orders filter, and obtain filtrate, filtrate are carried out cryogenic vacuum and is concentrated into the 1/3 of filtrate volume, obtain concentrated solution；
(5) step (4) concentrated solution is heated to 80 DEG C, add coco-nut oil fatty acid sodium, stir melt and dissolved 50min, adjust pH value to neutral, be then cooled to 40 DEG C, keep 4h, grinding tool is cooled to bulk, to obtain final product.
Embodiment 3
A kind of Chinese medicine sterilizing soap, including the Chinese medicine ingredients that weight ratio is 1:0.8 and palm oil fatty acid sodium, Chinese medicine ingredients is made up of the raw material of following parts by weight:
Flos Lonicerae 14 parts, Radix Scutellariae 19 parts, Cortex Cinnamomi 13 parts, Cortex Moutan 19 parts, Folium Artemisiae Argyi 11 parts, Flos Caryophylli 16 parts, the Radix Angelicae Dahuricae 11 parts, Borneolum Syntheticum 8 parts, 6 parts of Fructus Gleditsia and 18 parts of Radix Glycyrrhizae.
The preparation method of above-mentioned Chinese medicine sterilizing soap, comprises the following steps:
(1) raw material of above-mentioned each parts by weight is cleaned up, dry, broken；
(2) each raw material mixing after step (1) being crushed, adds 8 times amount water, decocts 3 times, each 40min, take decocting liquid, collect raw material slag；
(3) the raw material slag in step (2) is added 7 times amount water, continue to decoct 3 times, each 30min, take decocting liquid；
(4) combining step (2) and (3) decocting liquid, 60 orders filter, and obtain filtrate, filtrate are carried out cryogenic vacuum and is concentrated into the 1/3 of filtrate volume, obtain concentrated solution；
(5) step (4) concentrated solution is heated to 70 DEG C, add palm oil fatty acid sodium, stir melt and dissolved 20min, adjust pH value to neutral, be then cooled to 30 DEG C, keep 3h, grinding tool is cooled to bulk, to obtain final product.
Embodiment 4
A kind of Chinese medicine sterilizing soap, including the Chinese medicine ingredients that weight ratio is 1:0.8 and coco-nut oil fatty acid sodium, Chinese medicine ingredients is made up of the raw material of following parts by weight:
Flos Lonicerae 14 parts, Radix Scutellariae 19 parts, Cortex Cinnamomi 13 parts, Cortex Moutan 19 parts, Folium Artemisiae Argyi 11 parts, Flos Caryophylli 16 parts, the Radix Angelicae Dahuricae 11 parts, Borneolum Syntheticum 8 parts, 6 parts of Fructus Gleditsia, 18 parts of Radix Glycyrrhizae and Radix Angelicae Sinensis 15 parts.
Wherein, Radix Angelicae Sinensis external can expand peripheral blood vessel, reduces capillary of skin resistance, increases blood circulation, has the melanic formation of suppression, to the treatment pigmentosa dermopathic effect such as chloasma, freckle.
The preparation method of above-mentioned Chinese medicine sterilizing soap, comprises the following steps:
(1) raw material of above-mentioned each parts by weight is cleaned up, dry, broken；
(2) each raw material mixing after step (1) being crushed, adds 7 times amount water, decocts 3 times, each 40min, take decocting liquid, collect raw material slag；
(3) the raw material slag in step (2) is added 7 times amount water, continue to decoct 2 times, each 40min, take decocting liquid；
(4) combining step (2) and (3) decocting liquid, 80 orders filter, and obtain filtrate, filtrate are carried out cryogenic vacuum and is concentrated into the 1/3 of filtrate volume, obtain concentrated solution；
(5) step (4) concentrated solution is heated to 70 DEG C, add coco-nut oil fatty acid sodium, stir melt and dissolved 30min, adjust pH value to neutral, be then cooled to 30 DEG C, keep 3h, grinding tool is cooled to bulk, to obtain final product.
Embodiment 5
A kind of Chinese medicine sterilizing soap, including the Chinese medicine ingredients that weight ratio is 1:0.7 and palm oil fatty acid sodium, Chinese medicine ingredients is made up of the raw material of following parts by weight:
Flos Lonicerae 15 parts, Radix Scutellariae 20 parts, Cortex Cinnamomi 15 parts, Cortex Moutan 20 parts, Folium Artemisiae Argyi 12 parts, Flos Caryophylli 20 parts, the Radix Angelicae Dahuricae 12 parts, Borneolum Syntheticum 9 parts, 8 parts of Fructus Gleditsia and 20 parts of Radix Glycyrrhizae.
The preparation method of above-mentioned Chinese medicine sterilizing soap, comprises the following steps:
(1) raw material of above-mentioned each parts by weight is cleaned up, dry, broken；
(2) each raw material mixing after step (1) being crushed, adds 8 times amount water, decocts 2 times, each 40min, take decocting liquid, collect raw material slag；
(3) the raw material slag in step (2) is added 7 times amount water, continue to decoct 3 times, each 30min, take decocting liquid；
(4) combining step (2) and (3) decocting liquid, 50 orders filter, and obtain filtrate, filtrate are carried out cryogenic vacuum and is concentrated into the 1/2 of filtrate volume, obtain concentrated solution；
(5) step (4) concentrated solution is heated to 70 DEG C, add palm oil fatty acid sodium, stir melt and dissolved 20min, adjust pH value to neutral, be then cooled to 30 DEG C, keep 3.5h, grinding tool is cooled to bulk, to obtain final product.
Embodiment 6
A kind of Chinese medicine sterilizing soap, including the Chinese medicine ingredients that weight ratio is 1:0.6 and soya fatty acid sodium, Chinese medicine ingredients is made up of the raw material of following parts by weight:
Flos Lonicerae 19 parts, Radix Scutellariae 22 parts, Cortex Cinnamomi 15 parts, Cortex Moutan 25 parts, Folium Artemisiae Argyi 15 parts, Flos Caryophylli 25 parts, the Radix Angelicae Dahuricae 15 parts, Borneolum Syntheticum 10 parts, 10 parts of Fructus Gleditsia and 23 parts of Radix Glycyrrhizae.
The preparation method of above-mentioned Chinese medicine sterilizing soap, comprises the following steps:
(1) raw material of above-mentioned each parts by weight is cleaned up, dry, broken；
(2) each raw material mixing after step (1) being crushed, adds 10 times amount water, decocts 3 times, each 30min, take decocting liquid, collect raw material slag；
(3) the raw material slag in step (2) is added 5 times amount water, continue to decoct 2 times, each 40min, take decocting liquid；
(4) combining step (2) and (3) decocting liquid, 60 orders filter, and obtain filtrate, filtrate are carried out cryogenic vacuum and is concentrated into the 1/2 of filtrate volume, obtain concentrated solution；
(5) step (4) concentrated solution is heated to 80 DEG C, add soya fatty acid sodium, stir melt and dissolved 30min, adjust pH value to neutral, be then cooled to 30 DEG C, keep 4h, grinding tool is cooled to bulk, to obtain final product.
Embodiment 7
A kind of Chinese medicine sterilizing soap, is the Chinese medicine ingredients of 1:0.6:0.01, coco-nut oil fatty acid sodium and Plant fiber including weight ratio, and Chinese medicine ingredients is made up of the raw material of following parts by weight:
Flos Lonicerae 19 parts, Radix Scutellariae 22 parts, Cortex Cinnamomi 13 parts, Cortex Moutan 20 parts, Folium Artemisiae Argyi 12 parts, Flos Caryophylli 20 parts, the Radix Angelicae Dahuricae 15 parts, Borneolum Syntheticum 10 parts, 7 parts of Fructus Gleditsia and 20 parts of Radix Glycyrrhizae.
Described plant fiber length 400～600 μm, diameter 10～50nm.
The preparation method of above-mentioned Chinese medicine sterilizing soap, comprises the following steps:
(1) raw material of above-mentioned each parts by weight is cleaned up, dry, broken；
(2) each raw material mixing after step (1) being crushed, adds 10 times amount water, decocts 3 times, each 40min, take decocting liquid, collect raw material slag；
(3) the raw material slag in step (2) is added 6 times amount water, continue to decoct 3 times, each 30min, take decocting liquid；
(4) combining step (2) and (3) decocting liquid, 70 orders filter, and obtain filtrate, filtrate are carried out cryogenic vacuum and is concentrated into the 1/3 of filtrate volume, obtain concentrated solution；
(5) step (4) concentrated solution is heated to 80 DEG C, add coco-nut oil fatty acid sodium and Plant fiber, stir melt and dissolved 50min, adjust pH value to neutral, be then cooled to 30 DEG C, keep 3h, grinding tool is cooled to bulk, to obtain final product.
Embodiment 8
A kind of Chinese medicine sterilizing soap, is the Chinese medicine ingredients of 1:1.0:0.01, palm oil fatty acid sodium and Plant fiber including weight ratio, and Chinese medicine ingredients is made up of the raw material of following parts by weight:
Flos Lonicerae 14 parts, Radix Scutellariae 20 parts, Cortex Cinnamomi 13 parts, Cortex Moutan 19 parts, Folium Artemisiae Argyi 10 parts, Flos Caryophylli 17 parts, the Radix Angelicae Dahuricae 11 parts, Borneolum Syntheticum 8 parts, 6 parts of Fructus Gleditsia and 20 parts of Radix Glycyrrhizae.
The preparation method of above-mentioned Chinese medicine sterilizing soap, comprises the following steps:
(1) raw material of above-mentioned each parts by weight is cleaned up, dry, broken；
(2) each raw material mixing after step (1) being crushed, adds 8 times amount water, decocts 3 times, each 40min, take decocting liquid, collect raw material slag；
(3) the raw material slag in step (2) is added 7 times amount water, continue to decoct 3 times, each 30min, take decocting liquid；
(4) combining step (2) and (3) decocting liquid, 60 orders filter, and obtain filtrate, filtrate are carried out cryogenic vacuum and is concentrated into the 1/3 of filtrate volume, obtain concentrated solution；
(5) step (4) concentrated solution is heated to 70 DEG C, add palm oil fatty acid sodium and Plant fiber, stir melt and dissolved 20min, adjust pH value to neutral, be then cooled to 30 DEG C, keep 3h, grinding tool is cooled to bulk, to obtain final product.
Embodiment 9
A kind of Chinese medicine sterilizing soap, is the Chinese medicine ingredients of 1:1.1:0.01, soya fatty acid sodium and Plant fiber including weight ratio, and Chinese medicine ingredients is made up of the raw material of following parts by weight:
Flos Lonicerae 12 parts, Radix Scutellariae 18 parts, Cortex Cinnamomi 11 parts, Cortex Moutan 20 parts, Folium Artemisiae Argyi 10 parts, Flos Caryophylli 16 parts, the Radix Angelicae Dahuricae 12 parts, Borneolum Syntheticum 7 parts, 5 parts of Fructus Gleditsia and 20 parts of Radix Glycyrrhizae.
Described plant fiber length 400～600 μm, diameter 10～50nm.
The preparation method of above-mentioned Chinese medicine sterilizing soap, comprises the following steps:
(1) raw material of above-mentioned each parts by weight is cleaned up, dry, broken；
(2) each raw material mixing after step (1) being crushed, adds 6 times amount water, decocts 3 times, each 40min, take decocting liquid, collect raw material slag；
(3) the raw material slag in step (2) is added 6 times amount water, continue to decoct 3 times, each 20min, take decocting liquid；
(4) combining step (2) and (3) decocting liquid, 80 orders filter, and obtain filtrate, filtrate are carried out cryogenic vacuum and is concentrated into the 1/3 of filtrate volume, obtain concentrated solution；
(5) step (4) concentrated solution is heated to 80 DEG C, add soya fatty acid sodium and Plant fiber, stir melt and dissolved 40min, adjust pH value to neutral, be then cooled to 40 DEG C, keep 3h, grinding tool is cooled to bulk, to obtain final product.
Bacteriostatic experiment
Strains tested: staphylococcus aureus (Staphlococcusaureus), escherichia coli (Escherichiacoli), strain is both from Chinese agriculture Microbiological Culture Collection administrative center (ACCC)；
LB solid medium: take NaCl5g, peptone 10g, yeast extract 5g, agar 12g, adds in 1000mL distilled water, and stirring to each composition is completely dissolved, add dilute NaOH solution or rare HCl solution regulates the pH value of culture medium to 7.0, stand-by after high temperature sterilize 30min at 121 DEG C.
LB fluid medium: take NaCl5g, peptone 10g, yeast extract 5g, add in 1000mL distilled water, stirring to each composition is completely dissolved, and adds dilute NaOH solution or rare HCl solution regulates the pH value of culture medium to 7.0, stand-by after high temperature sterilize 30min at 121 DEG C.
Testing sample: taking the arbitrarily described Chinese medicine sterilizing soap of 10mg embodiment 1～9, to be dissolved in 1mL volumetric concentration be in 60% methanol aqueous solution；Antibiotic hydrochloric acid penicillin sodium is S. aureus-positive comparison, and antibiotic gentamicin sulfate is escherichia coli positive control, and antibiotic solution concentration is 1mg/mL；60% methanol is negative control；
Method of testing: above-mentioned strains tested is inoculated in two test tubes equipped with the 20mL of 5mL fluid medium by (1) respectively, cultivates bacterium solution to optium concentration under 35 DEG C of conditions；
(2) it is put in 45～50 DEG C of thermostat water baths after sterilized solid medium heating being dissolved, when solid medium temperature is equal with water temperature in water-bath, the bacterium solution of step (1) is added in the ratio that bacterium solution and solid medium volume ratio are 1:19, it is quickly poured in clean culture dish after shaking up, being positioned over by solid medium in aseptic culture case makes it cool down, and makes flat board；
(3) drawing 5 μ L samples, control sample, 60% methanol with liquid-transfering gun, unsettled drip on step (2) flat board, measure each sample antibacterial circle diameter, each sample repeats experiment three times respectively, averages.Test result is in Table 1.
Table 1 embodiment of the present invention 1～9 Chinese medicine sterilizing soap sterilization result
As can be seen from Table 1, golden yellow common coccus and escherichia coli are all had good inhibiting effect by Chinese medicine sterilizing soap of the present invention, and bactericidal effect is good.
Claims (8)
1. a Chinese medicine sterilizing soap, it is characterised in that including Chinese medicine ingredients and fatty acid sodium salt, described Chinese medicine ingredients is made up of the raw material of following parts by weight:
Flos Lonicerae 12～19 parts, Radix Scutellariae 16～22 parts, Cortex Cinnamomi 10～15 parts, Cortex Moutan 18～25 parts, Folium Artemisiae Argyi 8～15 parts, Flos Caryophylli 15～25 parts, the Radix Angelicae Dahuricae 10～15 parts, Borneolum Syntheticum 5～10 parts, 4～10 parts of Fructus Gleditsia and 16～23 parts of Radix Glycyrrhizae.
2. Chinese medicine sterilizing soap according to claim 1, it is characterised in that described Chinese medicine ingredients is made up of the raw material of following parts by weight:
Flos Lonicerae 13～15 parts, Radix Scutellariae 18～20 parts, Cortex Cinnamomi 11～15 parts, Cortex Moutan 18～20 parts, Folium Artemisiae Argyi 10～12 parts, Flos Caryophylli 16～20 parts, the Radix Angelicae Dahuricae 10～12 parts, Borneolum Syntheticum 6～9 parts, 5～8 parts of Fructus Gleditsia and 17～20 parts of Radix Glycyrrhizae.
3. Chinese medicine sterilizing soap according to claim 2, it is characterised in that described Chinese medicine ingredients is made up of the raw material of following parts by weight:
Flos Lonicerae 14 parts, Radix Scutellariae 19 parts, Cortex Cinnamomi 13 parts, Cortex Moutan 19 parts, Folium Artemisiae Argyi 11 parts, Flos Caryophylli 16 parts, the Radix Angelicae Dahuricae 11 parts, Borneolum Syntheticum 8 parts, 6 parts of Fructus Gleditsia and 18 parts of Radix Glycyrrhizae.
4. Chinese medicine sterilizing soap according to claim 1, it is characterised in that the Chinese medicine ingredients of described Chinese medicine sterilizing soap and the weight ratio of fatty acid sodium salt are 1:0.6～1.1.
5. Chinese medicine sterilizing soap according to claim 1, it is characterised in that described fatty acid sodium salt is coco-nut oil fatty acid sodium, palm oil fatty acid sodium or soya fatty acid sodium.
6. the Chinese medicine sterilizing soap according to any one of Claims 1 to 5, it is characterised in that also include Plant fiber, the weight ratio of Chinese medicine ingredients, fatty acid sodium salt and Plant fiber is 1:0.6～1.1:0.01.
7. Chinese medicine sterilizing soap according to claim 6, it is characterised in that described plant fiber length 400～600 μm, diameter 10～50nm.
8. the preparation method of the Chinese medicine sterilizing soap described in a claim 1, it is characterised in that comprise the following steps:
(1) raw material of each parts by weight is cleaned up, dry, broken；
(2) each raw material mixing after step (1) being crushed, adds 5～10 times amount water, decocts 2～3 times, each 20～40min, take decocting liquid, collect raw material slag；
(3) the raw material slag in step (2) is added 5～7 times amount water, continue decoction 2～3 times, each 20～40min, take decocting liquid；
(4) combining step (2) and (3) decocting liquid, 40～80 orders filter, and obtain filtrate, filtrate are carried out cryogenic vacuum and is concentrated into the 1/3～1/2 of filtrate volume, obtain concentrated solution；
(5) step (4) concentrated solution is heated to 70～80 DEG C, add fatty acid sodium salt, stir melt and dissolved 20～50min, adjust pH value to neutral, be then cooled to 30～45 DEG C, keep 3～4h, grinding tool is cooled to bulk, to obtain final product.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106635524A (en) * | 2016-08-28 | 2017-05-10 | 骆志明 | Heat-clearing antibacterial traditional Chinese medicine manual grinding soap |
| CN108034536A (en) * | 2017-12-14 | 2018-05-15 | 潘兆坤 | A kind of champignon soap and preparation method thereof |
| CN108485849A (en) * | 2018-03-30 | 2018-09-04 | 重庆正刚中医骨科医院有限公司 | Secret plant medicated soap |
| CN108559667A (en) * | 2017-12-30 | 2018-09-21 | 跨越生物科技（滁州）有限公司 | A kind of antibacterial handmade soap and preparation method thereof |
| CN108684729A (en) * | 2018-07-10 | 2018-10-23 | 李�杰 | Food steamer cleaning agent |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101270323A (en) * | 2008-04-22 | 2008-09-24 | 王跃进 | Degerming soap of natural plant |
| CN102911812A (en) * | 2012-11-02 | 2013-02-06 | 李旻 | Materia medica medicated soap composition and preparation method thereof |
| CN103666868A (en) * | 2013-12-18 | 2014-03-26 | 田英才 | Antiseptic and anti-inflammation moisturizing soap containing functional component |
| CN105018260A (en) * | 2015-07-13 | 2015-11-04 | 广西金昊生物科技有限公司 | Plant skin care toilet soap and preparation method thereof |
-
2016
- 2016-02-29 CN CN201610126216.1A patent/CN105779177B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101270323A (en) * | 2008-04-22 | 2008-09-24 | 王跃进 | Degerming soap of natural plant |
| CN102911812A (en) * | 2012-11-02 | 2013-02-06 | 李旻 | Materia medica medicated soap composition and preparation method thereof |
| CN103666868A (en) * | 2013-12-18 | 2014-03-26 | 田英才 | Antiseptic and anti-inflammation moisturizing soap containing functional component |
| CN105018260A (en) * | 2015-07-13 | 2015-11-04 | 广西金昊生物科技有限公司 | Plant skin care toilet soap and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 甘卉芳 栗建林 卢庆生: "《化妆品、洗涤用品、消毒剂和服饰中有害物质及其防护》", 31 January 2004 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106635524A (en) * | 2016-08-28 | 2017-05-10 | 骆志明 | Heat-clearing antibacterial traditional Chinese medicine manual grinding soap |
| CN108034536A (en) * | 2017-12-14 | 2018-05-15 | 潘兆坤 | A kind of champignon soap and preparation method thereof |
| CN108559667A (en) * | 2017-12-30 | 2018-09-21 | 跨越生物科技（滁州）有限公司 | A kind of antibacterial handmade soap and preparation method thereof |
| CN108485849A (en) * | 2018-03-30 | 2018-09-04 | 重庆正刚中医骨科医院有限公司 | Secret plant medicated soap |
| CN108684729A (en) * | 2018-07-10 | 2018-10-23 | 李�杰 | Food steamer cleaning agent |
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Effective date of registration: 20190408 Address after: 200040 C, D, 14 building, 618 Xikang Road, Jingan District, Shanghai. Applicant after: Shanghai Kaikai Industry Co.,Ltd. Address before: 474250 No. 188, 45 Group Zhongshan Street, Chengguan Town, Zhenping County, Nanyang City, Henan Province Applicant before: Jin Chuang |
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