[go: up one dir, main page]

CN105770725A - Pharmaceutical composition for treating hepatitis and preparing method and application thereof - Google Patents

Pharmaceutical composition for treating hepatitis and preparing method and application thereof Download PDF

Info

Publication number
CN105770725A
CN105770725A CN201610099368.7A CN201610099368A CN105770725A CN 105770725 A CN105770725 A CN 105770725A CN 201610099368 A CN201610099368 A CN 201610099368A CN 105770725 A CN105770725 A CN 105770725A
Authority
CN
China
Prior art keywords
radix
hepatitis
rhizoma
parts
fructus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610099368.7A
Other languages
Chinese (zh)
Inventor
李法军
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201610099368.7A priority Critical patent/CN105770725A/en
Publication of CN105770725A publication Critical patent/CN105770725A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/074—Ganoderma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285—Aucklandia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296—Epimedium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638—Ligustrum, e.g. Chinese privet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734—Crataegus (hawthorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/744—Gardenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/746—Morinda
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/748—Oldenlandia or Hedyotis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/884—Alismataceae (Water-plantain family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998—Hordeum (barley)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9064—Amomum, e.g. round cardamom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention provides a pharmaceutical composition for treating hepatitis.Traditional Chinese medicine components capable of clearing away heat and toxic materials, tonifying kidney and body, conditioning intestines and stomach, promoting blood circulation to remove blood stasis and improving body immunity are used in cooperation, the specific material and usage amount of each component are adjusted through repeated testing, and then the pharmaceutical composition is obtained and corresponding drugs for treating hepatitis and viruses are prepared.The drugs not only can effectively treat hepatitis patients, but also can effectively cure hepatitis virus carriers and effectively kill hepatitis viruses, has the advantages that raw materials are environment-friendly and healthy, drugs become effective quickly, treatment effect is good and side effect is small, and then the technical problems of drugs for treating hepatitis in the prior art that drugs become effective slowly, efficacy is poor and side effect is severe can be solved.

Description

A kind for the treatment of hepatitis pharmaceutical composition, preparation method and application
Technical field
The present invention relates to field of medicinal compositions, concrete, the present invention relates to a kind for the treatment of hepatitis pharmaceutical composition, preparation method and application.
Background technology
Hepatitis is the general designation of inflammation.Typically refer to by multiple paathogenic factor, such as virus, antibacterial, parasite, chemical toxicant, medicine, ethanol, role of autoimmune factors etc. make liver cell be damaged, the function of liver suffers damage, and causes a series of malaise symptoms of health and the exception of liver function index.If treated not in time, hepatitis can bring great hazardness to human body, for instance may further result in hepatic fibrosis, and develop into liver cirrhosis, even hepatocarcinoma, and this brings economic and spiritual dual-pressure also can to patient and family members.
Effectively treatment hepatitis also just day by day becomes the focus that people pay close attention to, and in prior art, also the medicine of exploitation treatment hepatitis has been carried out more research.At present, effective anti-hepatic-B virus medicine mainly has two big classes, and a class is interferon, another kind of for nucleoside medicine.The former is mainly most commonly seen with alpha-interferon, and the lamivudine in the latter's such as left-handed ucleosides is the most commonly used.But, both medicines are not only expensive, and side effect and toxic reaction are strong, and the injury of the human body other organs such as kidney is very big.
Chinese herbal medicine is China's conventional medicament, has the advantages such as wholistic therapy, side effect be little.Therefore, exploitation can treat the Chinese medicine composition of hepatitis, is also increasingly becoming the emphasis direction of novel hepatitis medicine research and development.
In view of this, the special proposition present invention.
Summary of the invention
The first object of the present invention is in that to provide a kind for the treatment of hepatitis compositions, described pharmaceutical composition by select have heat-clearing and toxic substances removing, the kidney invigorating benefit body, the intestines and stomach coordinating and blood circulation promoting and blood stasis dispelling and raising body immunity etc. drug effect pure Chinese medicinal components with the use of, and specifically select medical material and consumption thereof to be adjusted each component through repetition test, thus obtain Chinese medicine composition of the present invention.The immune system of hepatitis is had obvious adjustment effect by the medicine that the present composition prepares further, and lymphocytic conversion can be promoted, strengthen the phagocytic function of leukocyte and the immunologic function of cell, promote the generation of people's internal antibody, improve the immunologic function of human body.Further, medicine prepared by the present composition has significantly promotion liver cell regeneration and repair function, liver function can be made to be improved rapidly, can not only effectively treat hepatitis, additionally it is possible to effectively cure hepatitis virus carrier, effectively kill hepatitis virus, there is raw material green health, drug effect instant effect, good effect, the advantages such as side effect is little, such that it is able in solution prior art, treatment hepatitis medicament takes effect slowly, drug effect is poor and has the technical problem of bigger side effect.
The second object of the present invention is in that to provide a kind of method preparing treatment hepatitis pharmaceutical composition, described in the application of the invention, compositions is as raw material, and after pulverizing sieves further, can be used as drug use, not only processing method is simple and convenient, also there is medicine instant effect, good effect, the advantages such as side effect is little simultaneously.
3rd purpose of the present invention is in that the application providing described compositions in preparation treatment hepatitis medicament, in the present invention, described in the application of the invention, pharmaceutical composition is as raw material, therefore, may be used for medicine prepared by treating hepatitis further, obtained medicine has the effect of good treatment hepatitis, and can effectively remove hepatitis virus.
In order to realize the above-mentioned purpose of the present invention, spy by the following technical solutions:
nullA kind for the treatment of hepatitis pharmaceutical composition，According to parts by weight meter，Described compositions is mainly made up of following components: Radix Salviae Miltiorrhizae 5-30 part、Herba Epimedii 1-15 part、Rhizoma Atractylodis Macrocephalae 1-15 part、Poria 1-15 part、Radix Astragali 1-15 part、Herba Artemisiae Scopariae 10-50 part、Rhizoma Coptidis 1-15 part、Radix Et Rhizoma Rhei 1-20 part、Fructus Gardeniae 1-20 part、Herba Lysimachiae 5-30 part、Hedyotidis Diffusae 20-50 part、Herba Taraxaci 10-50 part、Rhizoma Polygoni Cuspidati 5-30 part、Rhizoma Smilacis Glabrae 1-20 part、Herba Patriniae 10-50 part、Radix Sophorae Tonkinensis 5-30 part、Semen Armeniacae Amarum 1-20 part、Kowtow 1-20 part in vain、Radix Aucklandiae 1-20 part、Rhizoma Alismatis 1-20 part、Semen Coicis 5-30 part、Radix Curcumae 1-20 part、Radix Paeoniae Rubra 5-30 part、Pericarpium Citri Reticulatae Viride 1-15 part、Pericarpium Citri Reticulatae 1-15 part、Fructus Crataegi 1-20 part、Massa Medicata Fermentata 1-20 part、Fructus Hordei Germinatus 1-20 part、Radix Rehmanniae 1-20 part、Radix Angelicae Sinensis 1-20 part、Radix Paeoniae Alba 1-20 part、Rhizoma Dioscoreae 1-20 part、Cortex Moutan 1-20 part、Radix Polygoni Multiflori 1-20 part、Semen Cuscutae 1-20 part、Herba Taxilli 1-20 part、Fructus Ligustri Lucidi 1-20 part、Radix Morindae Officinalis 1-20 part、Ganoderma 1-20 part、Lentinus Edodes 1-20 part、Radix Ginseng 1-20 part、Eupolyphaga 1-20 part、Fructus Mori 1-20 part、First sheet 1-20 part、Radix Glycyrrhizae 1-20 part.
In the present invention, by select have heat-clearing and toxic substances removing, the kidney invigorating benefit body, the intestines and stomach coordinating and blood circulation promoting and blood stasis dispelling and raising body immunity etc. drug effect Chinese medicinal components with the use of, and specifically select medical material and consumption thereof to be adjusted each component through repetition test, thus obtain Chinese medicine composition of the present invention.Hepatitis can not only effectively be treated by the medicine that the present composition is prepared further, can also effectively cure hepatitis virus carrier, and effectively kill hepatitis virus, there is raw material green health, medicine instant effect, good effect, the advantages such as side effect is little, such that it is able to solve the shortcoming that treatment hepatitis medicament in prior art takes effect slowly, drug effect is poor and has bigger side effect.
nullOptionally，In the present invention，According to parts by weight meter，Described compositions is made up of following components: Radix Salviae Miltiorrhizae 10-20 part、Herba Epimedii 1-10 part、Rhizoma Atractylodis Macrocephalae 1-10 part、Poria 1-10 part、Radix Astragali 1-10 part、Herba Artemisiae Scopariae 20-30 part、Rhizoma Coptidis 1-10 part、Radix Et Rhizoma Rhei 1-10 part、Fructus Gardeniae 1-10 part、Herba Lysimachiae 10-20 part、Hedyotidis Diffusae 30-40 part、Herba Taraxaci 20-30 part、Rhizoma Polygoni Cuspidati 10-20 part、Rhizoma Smilacis Glabrae 1-10 part、Herba Patriniae 20-30 part、Radix Sophorae Tonkinensis 10-20 part、Semen Armeniacae Amarum 1-10 part、Kowtow 1-10 part in vain、Radix Aucklandiae 1-10 part、Rhizoma Alismatis 1-10 part、Semen Coicis 10-20 part、Radix Curcumae 1-10 part、Radix Paeoniae Rubra 10-20 part、Pericarpium Citri Reticulatae Viride 1-10 part、Pericarpium Citri Reticulatae 1-10 part、Fructus Crataegi 1-10 part、Massa Medicata Fermentata 1-10 part、Fructus Hordei Germinatus 1-10 part、Radix Rehmanniae 1-10 part、Radix Angelicae Sinensis 1-10 part、Radix Paeoniae Alba 1-10 part、Rhizoma Dioscoreae 1-10 part、Cortex Moutan 1-10 part、Radix Polygoni Multiflori 1-10 part、Semen Cuscutae 1-10 part、Herba Taxilli 1-10 part、Fructus Ligustri Lucidi 1-10 part、Radix Morindae Officinalis 1-10 part、Ganoderma 1-10 part、Lentinus Edodes 1-10 part、Radix Ginseng 1-10 part、Eupolyphaga 1-10 part、Fructus Mori 1-10 part、First sheet 1-10 part、Radix Glycyrrhizae 1-10 part.
In the present invention, by the further adjustment to each raw material components consumption, thus optimizing the drug effect of medicine prepared by pharmaceutical composition of the present invention further, take good care of patient's gastrointestinal function further.
Optionally, in the present invention, described Fructus Crataegi, Massa Medicata Fermentata and Fructus Hordei Germinatus respectively cooked Fructus Crataegi, ripe Massa Medicata Fermentata and ripe Fructus Hordei Germinatus.
In the present invention, by using the ripening raw materials such as cooked Fructus Crataegi, ripe Massa Medicata Fermentata and ripe Fructus Hordei Germinatus, thus improve effect of present composition the intestines and stomach coordinating, and then further increase the drug effect of pharmaceutical composition of the present invention.
Meanwhile, the preparation method that present invention also offers a kind for the treatment of hepatitis medicine, described method comprises the steps:, by pulverizing after each component Homogeneous phase mixing of composition as described above, then to sieve, obtain described treating hepatitis medicine.
In the present invention, after being sieved by the further pulverizing of each raw material of compositions, can be used as medicine and eat, not only processing method is simple and convenient, also has medicine instant effect, good effect, the advantages such as side effect is little simultaneously.
Optionally, in the present invention, the hybrid medicine powder after screening after direct boiled water brews, and can drink medicinal liquid.
Optionally, in the present invention, medicinal liquid after direct boiled water brews, together can be eaten by the drug powder after screening with brewing rear drug powder.
Optionally, in the present invention, described in the mesh size used that sieves be 50-200 order.
In the present invention, by selecting further and adjusting screening mesh size used, so that obtained medicine has suitable particle diameter, the utilization so that the effective ingredient in medicine can fully dissolve and/or precipitate out and be absorbed by the body.
Optionally, in the present invention, after described method farther includes first Fructus Crataegi, Massa Medicata Fermentata and Fructus Hordei Germinatus to be fried, then mix with all the other components, then the step pulverized and sieved.
In the present invention, by having after the Fructus Crataegi of stomach invigorating effect, Massa Medicata Fermentata and Fructus Hordei Germinatus fry as raw material components, thus the strong the intestines and stomach effect of medicine obtained by the present composition can be improved.
Optionally, in the present invention, described in be mixed into mechanical mixture.
Same, present invention also offers a kind for the treatment of hepatitis medicine, described medicine is prepared by the method for the invention.
Further, present invention also offers composition as described above application in preparation treatment hepatitis medicament.
In the present invention, described in the application of the invention, pharmaceutical composition is as raw material, therefore, may be used for medicine prepared by treating hepatitis further, and obtained medicine has the effect of good treatment hepatitis, and has the advantages such as instant effect.
Optionally, in the present invention, described hepatitis is the one in hepatitis A, hepatitis B, hepatitis C, hepatitis D or hepatitis E.
Preferably, in the present invention, described hepatitis is hepatitis B.Further, described hepatitis B can be acute hepatitis b or chronic viral hepatitis B.
Same, present invention also offers composition as described above and remove the application in hepatitis virus medicament in preparation.
Optionally, in the present invention, described hepatitis virus is hepatitis A virus (HAV), hepatitis B virus, hepatitis C virus, hepatitis D virus or Hepatitis E virus.
Preferably, in the present invention, described hepatitis virus is hepatitis B virus.
Compared with prior art, the invention have the benefit that
(1) in the present invention, by select have heat-clearing and toxic substances removing, the kidney invigorating benefit body, the intestines and stomach coordinating and blood circulation promoting and blood stasis dispelling and raising body immunity etc. drug effect Chinese medicinal components with the use of, and specifically select medical material and consumption thereof to be adjusted each component through repetition test, thus obtain Chinese medicine composition of the present invention.The present composition has raw material green health, instant effect, good effect, the advantages such as side effect is little, such that it is able in solution prior art, treatment hepatitis medicament takes effect slowly, drug effect is poor and has the technical problem of bigger side effect etc..
(2) in the method for the invention, described in the application of the invention, compositions is as raw material, and after further pulverizing sieves, can be used as medicine and eat, and not only processing method is simple and convenient, also has medicine instant effect, good effect, the advantages such as side effect is little simultaneously.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, it will be appreciated by those skilled in the art that the following example is merely to illustrate the present invention, and are not construed as restriction the scope of the present invention.Unreceipted actual conditions person in embodiment, conventionally the condition of condition or manufacturer's suggestion carries out.Agents useful for same or the unreceipted production firm person of instrument, be and can pass through the commercially available conventional products bought and obtain.
Embodiment 1
nullAccording to following prescription，Appropriate raw material is weighed respectively according to parts by weight，Wherein，Radix Salviae Miltiorrhizae 5 parts、Herba Epimedii 1 part、The Rhizoma Atractylodis Macrocephalae 1 part、Poria 1 part、The Radix Astragali 1 part、Herba Artemisiae Scopariae 10 parts、Rhizoma Coptidis 1 part、Radix Et Rhizoma Rhei 1 part、Fructus Gardeniae 1 part、Herba Lysimachiae 5 parts、Hedyotidis Diffusae 20 parts、Herba Taraxaci 10 parts、Rhizoma Polygoni Cuspidati 5 parts、Rhizoma Smilacis Glabrae 1 part、Herba Patriniae 10 parts、Radix Sophorae Tonkinensis 5 parts、1 part of Semen Armeniacae Amarum、Kowtow 1 part in vain、The Radix Aucklandiae 1 part、Rhizoma Alismatis 1 part、Semen Coicis 5 parts、Radix Curcumae 1-20 part、Radix Paeoniae Rubra 5-30 part、Pericarpium Citri Reticulatae Viride 1-15 part、Pericarpium Citri Reticulatae 1-15 part、Fructus Crataegi 1-20 part、Massa Medicata Fermentata 1-20 part、Fructus Hordei Germinatus 1-20 part、Radix Rehmanniae 1-20 part、Radix Angelicae Sinensis 1-20 part、Radix Paeoniae Alba 1-20 part、Rhizoma Dioscoreae 1-20 part、Cortex Moutan 1-20 part、Radix Polygoni Multiflori 1-20 part、Semen Cuscutae 1-20 part、Herba Taxilli 1-20 part、Fructus Ligustri Lucidi 1-20 part、Radix Morindae Officinalis 1-20 part、Ganoderma 1-20 part、Lentinus Edodes 1-20 part、Radix Ginseng 1-20 part、Eupolyphaga 1-20 part、Fructus Mori 1-20 part、First sheet 1-20 part、Radix Glycyrrhizae 1-20 part.
Then, raw material is pulverized after mechanical mixture, and by the screen cloth screening that compositions aperture after pulverizing is 50 orders, namely obtain the Chinese medicine composition of embodiment 1.
Embodiment 2
nullAccording to following prescription，Appropriate raw material is weighed respectively according to parts by weight，Wherein，Radix Salviae Miltiorrhizae 30 parts、Herba Epimedii 15 parts、The Rhizoma Atractylodis Macrocephalae 15 parts、Poria 15 parts、The Radix Astragali 15 parts、Herba Artemisiae Scopariae 10 parts、Rhizoma Coptidis 15 parts、Radix Et Rhizoma Rhei 12 parts、Fructus Gardeniae 15 parts、Herba Lysimachiae 13 parts、Hedyotidis Diffusae 25 parts、Herba Taraxaci 15 parts、Rhizoma Polygoni Cuspidati 20 parts、Rhizoma Smilacis Glabrae 16 parts、Herba Patriniae 19 parts、Radix Sophorae Tonkinensis 15 parts、2 parts of Semen Armeniacae Amarum、Kowtow 10 parts in vain、The Radix Aucklandiae 20 parts、Rhizoma Alismatis 20 parts、Semen Coicis 5 parts、Radix Curcumae 20 parts、Radix Paeoniae Rubra 5 parts、1 part of Pericarpium Citri Reticulatae Viride、Pericarpium Citri Reticulatae 5 parts、Fructus Crataegi 10 parts、Massa Medicata Fermentata 10 parts、15 parts of Fructus Hordei Germinatus、15 parts of the Radix Rehmanniae、Radix Angelicae Sinensis 10 parts、The Radix Paeoniae Alba 20 parts、Rhizoma Dioscoreae 20 parts、Cortex Moutan 1 part、The Radix Polygoni Multiflori 20 parts、Semen Cuscutae 20 parts、Herba Taxilli 20 parts、Fructus Ligustri Lucidi 20 parts、Radix Morindae Officinalis 20 parts、Ganoderma 20 parts、20 parts of Lentinus Edodes、Radix Ginseng 5 parts、Eupolyphaga 20 parts、Fructus Mori 20 parts、First sheet 20 parts、20 parts of Radix Glycyrrhizae.
Wherein, after Fructus Crataegi, Massa Medicata Fermentata and Fructus Hordei Germinatus fry, then mix with other components.
Then, method described in embodiment 1 prepares the Chinese medicine composition of embodiment 2.
Embodiment 3
nullAccording to following prescription，Appropriate raw material is weighed respectively according to parts by weight，Wherein，Radix Salviae Miltiorrhizae 10 parts、Herba Epimedii 10 parts、The Rhizoma Atractylodis Macrocephalae 5 parts、Poria 5 parts、The Radix Astragali 10 parts、Herba Artemisiae Scopariae 20 parts、Rhizoma Coptidis 5 parts、Radix Et Rhizoma Rhei 10 parts、Fructus Gardeniae 5 parts、Herba Lysimachiae 10 parts、Hedyotidis Diffusae 30 parts、Herba Taraxaci 20 parts、Rhizoma Polygoni Cuspidati 10 parts、Rhizoma Smilacis Glabrae 10 parts、Herba Patriniae 20 parts、Radix Sophorae Tonkinensis 10 parts、10 parts of Semen Armeniacae Amarum、Kowtow 10 parts in vain、The Radix Aucklandiae 10 parts、Rhizoma Alismatis 10 parts、Semen Coicis 10 parts、Radix Curcumae 10 parts、Radix Paeoniae Rubra 20 parts、10 parts of Pericarpium Citri Reticulatae Viride、Pericarpium Citri Reticulatae 10 parts、Fructus Crataegi 10 parts、Massa Medicata Fermentata 10 parts、10 parts of Fructus Hordei Germinatus、10 parts of the Radix Rehmanniae、Radix Angelicae Sinensis 10 parts、The Radix Paeoniae Alba 10 parts、Rhizoma Dioscoreae 10 parts、Cortex Moutan 10 parts、The Radix Polygoni Multiflori 10 parts、Semen Cuscutae 10 parts、Herba Taxilli 10 parts、Fructus Ligustri Lucidi 10 parts、Radix Morindae Officinalis 10 parts、Ganoderma 10 parts、10 parts of Lentinus Edodes、Radix Ginseng 2 parts、Eupolyphaga 10 parts、Fructus Mori 10 parts、First sheet 10 parts、10 parts of Radix Glycyrrhizae.
Wherein, Fructus Crataegi, Massa Medicata Fermentata and Fructus Hordei Germinatus are cooked Fructus Crataegi, ripe Massa Medicata Fermentata and ripe Fructus Hordei Germinatus.
Then, method described in embodiment 1 prepares the Chinese medicine composition of embodiment 3.
Experimental example 1
60 example cases, selected from the patient that diagnosis is chronic hepatitis B, diagnostic criteria is according to " Diagnosis of Viral Hapatitis standard ".Wherein male 30 example, women 30 example.
Front HBV label: the HBSAg for the treatment of (+) person 60 example, HBeAg (+) person 60 example.
60 patients are equally divided into 3 groups, often 10 male, 10 women of group, and treat with medicine described in embodiment 1-3 respectively.Specific as follows: to weigh the Chinese medicine composition obtained by 150g (half agent) embodiment 1-3 respectively, after then it being soaked 2h in hot water, drink medicinal liquid, once a day, continue 30.
After treatment, 3 groups of HBSAg and HBeAg amounting to 60 patients all turn (-), check after 90 days, do not find HBSAg or HBeAg turn (+), further, do not find that medicine has any side effect yet.
But, with the some patients of the traditional Chinese medicine composition for treating of embodiment 1 slightly lack of appetite poor appetite symptom, but the patient of the traditional Chinese medicine composition for treating of embodiment 2,3 there is no above-mentioned symptom.
Experimental example 2
90 example cases, selected from the patient that diagnosis is acute hepatitis B, diagnostic criteria is according to " Diagnosis of Viral Hapatitis standard ".Wherein male 45 example, women 45 example.
Front HBV label: the HBSAg for the treatment of (+) person 90 example, HBeAg (+) person 90 example.
90 patients are equally divided into 3 groups, often 15 male, 15 women of group, and treat with medicine described in embodiment 1-3 respectively.Specific as follows: to weigh the Chinese medicine composition obtained by 300g (potion) embodiment 1-3 respectively, after then it being soaked 2h in hot water, drink medicinal liquid, once a day, continue 15.
After treatment, 3 groups of HBSAg and HBeAg amounting to 90 patients all turn (-), check after 90 days, do not find HBSAg or HBeAg turn (+), meanwhile, find that medicine has side effect to occur.
Wherein, with the some patients of the traditional Chinese medicine composition for treating of embodiment 1 slightly lack of appetite poor appetite symptom, there is no above-mentioned symptom with the patient of the traditional Chinese medicine composition for treating of embodiment 2,3.
Experimental example 3
90 example cases, are hepatitis B virus carriers selected from diagnosis, and HBV carrier state are all more than 6 months, liver function is normal, and gets rid of hepatocarcinoma, various infection, rheumatism and tuberculosis etc..Wherein male 45 example, women 45 example.
Front HBV label: the HBSAg for the treatment of (+) person 90 example, HBeAg (+) person 90 example.
90 patients are equally divided into 3 groups, often 15 male, 15 women of group, and treat with medicine described in embodiment 1-3 respectively.Specific as follows: to weigh the Chinese medicine composition obtained by 30g embodiment 1-3 respectively, after then it being soaked 2h in hot water, drink medicinal liquid, once a day, continue (two courses for the treatment of) on the 180th.
After treatment, 3 groups of HBSAg and HBeAg amounting to 90 patients all turn (-), check after 90 days, do not find HBSAg or HBeAg turn (+), any other side effect does not occur yet.
Wherein, with the some patients of the traditional Chinese medicine composition for treating of embodiment 1 slightly lack of appetite poor appetite symptom, there is no above-mentioned symptom with the patient of the traditional Chinese medicine composition for treating of embodiment 2,3.
Chinese medicine composition of the present invention takes simplicity, and can effectively treat hepatitis and hepatitis virus, has instant effect, a good effect, and the advantage such as have no side effect.
Although illustrate and describing the present invention with specific embodiment, however it will be appreciated that may be made that when without departing substantially from the spirit and scope of the present invention many other change and amendment.It is, therefore, intended that include all such changes and modifications belonging in the scope of the invention in the following claims.

Claims (10)

  1. null1. a treating hepatitis pharmaceutical composition，It is characterized in that，According to parts by weight meter，Described compositions is mainly made up of following components: Radix Salviae Miltiorrhizae 5-30 part、Herba Epimedii 1-15 part、Rhizoma Atractylodis Macrocephalae 1-15 part、Poria 1-15 part、Radix Astragali 1-15 part、Herba Artemisiae Scopariae 10-50 part、Rhizoma Coptidis 1-15 part、Radix Et Rhizoma Rhei 1-20 part、Fructus Gardeniae 1-20 part、Herba Lysimachiae 5-30 part、Hedyotidis Diffusae 20-50 part、Herba Taraxaci 10-50 part、Rhizoma Polygoni Cuspidati 5-30 part、Rhizoma Smilacis Glabrae 1-20 part、Herba Patriniae 10-50 part、Radix Sophorae Tonkinensis 5-30 part、Semen Armeniacae Amarum 1-20 part、Kowtow 1-20 part in vain、Radix Aucklandiae 1-20 part、Rhizoma Alismatis 1-20 part、Semen Coicis 5-30 part、Radix Curcumae 1-20 part、Radix Paeoniae Rubra 5-30 part、Pericarpium Citri Reticulatae Viride 1-15 part、Pericarpium Citri Reticulatae 1-15 part、Fructus Crataegi 1-20 part、Massa Medicata Fermentata 1-20 part、Fructus Hordei Germinatus 1-20 part、Radix Rehmanniae 1-20 part、Radix Angelicae Sinensis 1-20 part、Radix Paeoniae Alba 1-20 part、Rhizoma Dioscoreae 1-20 part、Cortex Moutan 1-20 part、Radix Polygoni Multiflori 1-20 part、Semen Cuscutae 1-20 part、Herba Taxilli 1-20 part、Fructus Ligustri Lucidi 1-20 part、Radix Morindae Officinalis 1-20 part、Ganoderma 1-20 part、Lentinus Edodes 1-20 part、Radix Ginseng 1-20 part、Eupolyphaga 1-20 part、Fructus Mori 1-20 part、First sheet 1-20 part、Radix Glycyrrhizae 1-20 part.
  2. null2. compositions according to claim 1，It is characterized in that，According to parts by weight meter，Described compositions is made up of following components: Radix Salviae Miltiorrhizae 10-20 part、Herba Epimedii 1-10 part、Rhizoma Atractylodis Macrocephalae 1-10 part、Poria 1-10 part、Radix Astragali 1-10 part、Herba Artemisiae Scopariae 20-30 part、Rhizoma Coptidis 1-10 part、Radix Et Rhizoma Rhei 1-10 part、Fructus Gardeniae 1-10 part、Herba Lysimachiae 10-20 part、Hedyotidis Diffusae 30-40 part、Herba Taraxaci 20-30 part、Rhizoma Polygoni Cuspidati 10-20 part、Rhizoma Smilacis Glabrae 1-10 part、Herba Patriniae 20-30 part、Radix Sophorae Tonkinensis 10-20 part、Semen Armeniacae Amarum 1-10 part、Kowtow 1-10 part in vain、Radix Aucklandiae 1-10 part、Rhizoma Alismatis 1-10 part、Semen Coicis 10-20 part、Radix Curcumae 1-10 part、Radix Paeoniae Rubra 10-20 part、Pericarpium Citri Reticulatae Viride 1-10 part、Pericarpium Citri Reticulatae 1-10 part、Fructus Crataegi 1-10 part、Massa Medicata Fermentata 1-10 part、Fructus Hordei Germinatus 1-10 part、Radix Rehmanniae 1-10 part、Radix Angelicae Sinensis 1-10 part、Radix Paeoniae Alba 1-10 part、Rhizoma Dioscoreae 1-10 part、Cortex Moutan 1-10 part、Radix Polygoni Multiflori 1-10 part、Semen Cuscutae 1-10 part、Herba Taxilli 1-10 part、Fructus Ligustri Lucidi 1-10 part、Radix Morindae Officinalis 1-10 part、Ganoderma 1-10 part、Lentinus Edodes 1-10 part、Radix Ginseng 1-10 part、Eupolyphaga 1-10 part、Fructus Mori 1-10 part、First sheet 1-10 part、Radix Glycyrrhizae 1-10 part.
  3. 3. compositions according to claim 1 and 2, it is characterised in that described Fructus Crataegi, Massa Medicata Fermentata and Fructus Hordei Germinatus respectively cooked Fructus Crataegi, ripe Massa Medicata Fermentata and ripe Fructus Hordei Germinatus.
  4. 4. the preparation method of a treating hepatitis pharmaceutical composition, it is characterised in that: described method comprises the steps: to pulverize after each component Homogeneous phase mixing of compositions according to any one of claim 1-3, then sieves, obtains described treating hepatitis medicine.
  5. 5. method according to claim 4, it is characterised in that described in the mesh size that sieves be 50-200 order.
  6. 6. method according to claim 4, it is characterised in that after described method farther includes first Fructus Crataegi, Massa Medicata Fermentata and Fructus Hordei Germinatus to be fried, then mix with all the other components, the step then pulverized and sieved.
  7. 7. method according to claim 4, it is characterised in that described in be mixed into mechanical mixture.
  8. 8. the application in preparation treatment hepatitis medicament of the compositions according to any one of claim 1-3.
  9. 9. apply according to claim 8, it is characterised in that described hepatitis is hepatitis B.
  10. 10. compositions any one of claim 1-3 removes the application in hepatitis virus medicament in preparation.
CN201610099368.7A 2016-02-23 2016-02-23 Pharmaceutical composition for treating hepatitis and preparing method and application thereof Pending CN105770725A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610099368.7A CN105770725A (en) 2016-02-23 2016-02-23 Pharmaceutical composition for treating hepatitis and preparing method and application thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610099368.7A CN105770725A (en) 2016-02-23 2016-02-23 Pharmaceutical composition for treating hepatitis and preparing method and application thereof

Publications (1)

Publication Number Publication Date
CN105770725A true CN105770725A (en) 2016-07-20

Family

ID=56403539

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610099368.7A Pending CN105770725A (en) 2016-02-23 2016-02-23 Pharmaceutical composition for treating hepatitis and preparing method and application thereof

Country Status (1)

Country Link
CN (1) CN105770725A (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1113779A (en) * 1994-06-17 1995-12-27 殷广全 Anti- hepatitis B preparation
CN101612360A (en) * 2009-07-17 2009-12-30 肖嘉惠 The medicine of treatment hepatitis, liver cirrhosis, hepatocarcinoma
CN101773655A (en) * 2009-01-09 2010-07-14 苏州知微堂生物科技有限公司 Anti-AIDS nanometer Chinese medicine and production method thereof
CN102755594A (en) * 2012-07-19 2012-10-31 杨国兴 Traditional Chinese medicine composition for treating acute and chronic hepatitis B and preparation method thereof
CN104547070A (en) * 2014-12-25 2015-04-29 成都中医药大学 Medical composition resistant to hepatitis b viruses as well as preparation method and application of medical composition

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1113779A (en) * 1994-06-17 1995-12-27 殷广全 Anti- hepatitis B preparation
CN101773655A (en) * 2009-01-09 2010-07-14 苏州知微堂生物科技有限公司 Anti-AIDS nanometer Chinese medicine and production method thereof
CN101612360A (en) * 2009-07-17 2009-12-30 肖嘉惠 The medicine of treatment hepatitis, liver cirrhosis, hepatocarcinoma
CN102755594A (en) * 2012-07-19 2012-10-31 杨国兴 Traditional Chinese medicine composition for treating acute and chronic hepatitis B and preparation method thereof
CN104547070A (en) * 2014-12-25 2015-04-29 成都中医药大学 Medical composition resistant to hepatitis b viruses as well as preparation method and application of medical composition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
胡智明等: "乙肝宝冲剂的研制与疗效观察", 《现代中药研究与实践》 *

Similar Documents

Publication Publication Date Title
CN1044974C (en) Anti- hepatitis B preparation
CN101468171B (en) Medicament for weight-reducing of fat people and weight-gaining of thin people
CN1194843A (en) Method for producing green health medicine
CN1047946C (en) Preparation for treating senile diseases
CN1951481A (en) Medicament for treating cerebral thrombosis
CN100998838A (en) Chinese medicine for relaxing muscles and tendons to promote blood circulation preparation method thereof
CN101947300B (en) Traditional Chinese medicinal composition for treating liver diseases, preparation method thereof and use thereof
CN1087625C (en) Traditional Chinese medicine preparation for treating colitis
CN1145240A (en) Medicinal compsn. for prevention of Aids virus and cancer
CN1186687A (en) Cancer preventing curing medicine series and its preparation
CN1063954C (en) Chinese patent medicine-powder preparation for curing hepatitis B
CN101167932A (en) Traditional Chinese medicine for treating chronic hepatitis B
CN101940759A (en) Chinese medicinal composition for treating liver diseases and preparation method and application thereof
CN101940758B (en) Traditional Chinese medicinal composition for treating liver diseases, preparation method thereof and application thereof
CN1058165C (en) Chinese drugs for curing hepatitis B
CN1242775C (en) Bushenshansong drink and preparation method thereof
CN105770725A (en) Pharmaceutical composition for treating hepatitis and preparing method and application thereof
CN113456728A (en) A Chinese medicinal oral liquid for treating chronic hepatitis B, and its preparation method
CN1453014A (en) Chinese medicine prepn for preventing fibrillated liver and treating hepatocirrhosis
CN101987188B (en) Biological Chinese patent medicine for preventing and treating hyperlipidemia
CN104127602A (en) Traditional Chinese medicine for treating fatty liver
CN1145229A (en) A manufacturing method of cleansing powder for human viscera
CN1969940A (en) Antivirus pharmaceutical composition
CN101991762A (en) Traditional Chinese medicine for treating refractory asthma and preparation method thereof
CN101229291B (en) Chinese traditional medicine composition for treating virus hepatitis by immunoregulation

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20160720

RJ01 Rejection of invention patent application after publication