CN105769603A - Micro-injection powder foundation and preparation method thereof - Google Patents
Micro-injection powder foundation and preparation method thereof Download PDFInfo
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- CN105769603A CN105769603A CN201610117724.3A CN201610117724A CN105769603A CN 105769603 A CN105769603 A CN 105769603A CN 201610117724 A CN201610117724 A CN 201610117724A CN 105769603 A CN105769603 A CN 105769603A
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- 238000000520 microinjection Methods 0.000 title claims abstract description 25
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 239000000843 powder Substances 0.000 title claims abstract description 4
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 22
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 22
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims abstract description 22
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 claims abstract description 21
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 claims abstract description 21
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims abstract description 20
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims abstract description 11
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims abstract description 11
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims abstract description 11
- BAWFJGJZGIEFAR-NNYOXOHSSA-N NAD zwitterion Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-N 0.000 claims abstract description 11
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 claims abstract description 11
- 229960005070 ascorbic acid Drugs 0.000 claims abstract description 11
- 235000010323 ascorbic acid Nutrition 0.000 claims abstract description 11
- 239000011668 ascorbic acid Substances 0.000 claims abstract description 11
- 239000001110 calcium chloride Substances 0.000 claims abstract description 11
- 229910001628 calcium chloride Inorganic materials 0.000 claims abstract description 11
- 229920002674 hyaluronan Polymers 0.000 claims abstract description 11
- 229960003160 hyaluronic acid Drugs 0.000 claims abstract description 11
- 229950006238 nadide Drugs 0.000 claims abstract description 11
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 claims abstract description 11
- 239000011607 retinol Substances 0.000 claims abstract description 11
- 229960003471 retinol Drugs 0.000 claims abstract description 11
- 235000020944 retinol Nutrition 0.000 claims abstract description 11
- 239000011780 sodium chloride Substances 0.000 claims abstract description 11
- 230000003712 anti-aging effect Effects 0.000 claims abstract description 10
- 239000005515 coenzyme Substances 0.000 claims abstract description 10
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims abstract description 10
- 235000019341 magnesium sulphate Nutrition 0.000 claims abstract description 10
- 229910000403 monosodium phosphate Inorganic materials 0.000 claims abstract description 10
- 235000019799 monosodium phosphate Nutrition 0.000 claims abstract description 10
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 claims abstract description 10
- 239000000463 material Substances 0.000 claims abstract description 8
- 239000002537 cosmetic Substances 0.000 claims description 24
- 229940079593 drug Drugs 0.000 claims description 24
- 239000003814 drug Substances 0.000 claims description 24
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 20
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 20
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 claims description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 235000011187 glycerol Nutrition 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 10
- 239000004408 titanium dioxide Substances 0.000 claims description 10
- WTFXARWRTYJXII-UHFFFAOYSA-N iron(2+);iron(3+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[O-2].[Fe+2].[Fe+3].[Fe+3] WTFXARWRTYJXII-UHFFFAOYSA-N 0.000 claims description 9
- SZVJSHCCFOBDDC-UHFFFAOYSA-N iron(II,III) oxide Inorganic materials O=[Fe]O[Fe]O[Fe]=O SZVJSHCCFOBDDC-UHFFFAOYSA-N 0.000 claims description 9
- 239000000243 solution Substances 0.000 claims description 7
- 239000001052 yellow pigment Substances 0.000 claims description 5
- 239000012528 membrane Substances 0.000 claims description 4
- 239000001054 red pigment Substances 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- 238000002525 ultrasonication Methods 0.000 claims description 4
- 239000003086 colorant Substances 0.000 claims description 2
- 239000004615 ingredient Substances 0.000 claims description 2
- LDHBWEYLDHLIBQ-UHFFFAOYSA-M iron(3+);oxygen(2-);hydroxide;hydrate Chemical compound O.[OH-].[O-2].[Fe+3] LDHBWEYLDHLIBQ-UHFFFAOYSA-M 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims description 2
- 230000006641 stabilisation Effects 0.000 claims description 2
- 238000011105 stabilization Methods 0.000 claims description 2
- 238000004040 coloring Methods 0.000 claims 4
- NFIYTPYOYDDLGO-UHFFFAOYSA-N phosphoric acid;sodium Chemical compound [Na].OP(O)(O)=O NFIYTPYOYDDLGO-UHFFFAOYSA-N 0.000 claims 1
- 239000011148 porous material Substances 0.000 abstract description 12
- 230000000694 effects Effects 0.000 abstract description 6
- 229960002713 calcium chloride Drugs 0.000 abstract description 3
- 230000003203 everyday effect Effects 0.000 abstract description 3
- 229960002668 sodium chloride Drugs 0.000 abstract description 3
- 238000000227 grinding Methods 0.000 abstract description 2
- 238000002347 injection Methods 0.000 abstract description 2
- 239000007924 injection Substances 0.000 abstract description 2
- 238000007920 subcutaneous administration Methods 0.000 abstract description 2
- 210000003491 skin Anatomy 0.000 description 5
- 239000001060 yellow colorant Substances 0.000 description 5
- 239000002245 particle Substances 0.000 description 4
- 230000002354 daily effect Effects 0.000 description 3
- 241000282414 Homo sapiens Species 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 210000002615 epidermis Anatomy 0.000 description 2
- 230000008676 import Effects 0.000 description 2
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 1
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 229930003756 Vitamin B7 Natural products 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229960002685 biotin Drugs 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 239000001062 red colorant Substances 0.000 description 1
- 235000011912 vitamin B7 Nutrition 0.000 description 1
- 239000011735 vitamin B7 Substances 0.000 description 1
Classifications
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/23—Sulfur; Selenium; Tellurium; Compounds thereof
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- A—HUMAN NECESSITIES
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- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/345—Alcohols containing more than one hydroxy group
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- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
- A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
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- A61K8/67—Vitamins
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
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- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
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- Chemical & Material Sciences (AREA)
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- Biochemistry (AREA)
- Molecular Biology (AREA)
- Cosmetics (AREA)
Abstract
Description
技术领域technical field
本发明具体涉及一种粉底，更具体地说，涉及一种微注粉底及其制备方法。The invention specifically relates to a foundation, more specifically, relates to a micro-injection foundation and a preparation method thereof.
背景技术Background technique
粉底是妆容的基础，粉状质地的粉底是最常见的，涂在脸上显得轻柔自然，是日常妆的选择，其类型也很多，中国专利CN104688590A公开了一种保湿透气粉底，中国专利CN104069014A公开了一种可控变色的粉底霜/粉底液及其制备方法等等，但是，日常的粉底在使用过程中也有很多的问题，常规的粉底由于涂在脸上会使皮肤毛孔粗大，产生痘痘，同时在日常生活中也很不方便，经常因为一些大的活动而破坏其妆容，同时也需要每天都进行化妆，而耽搁大量的时间，为此，寻找一种良好的粉底是十分必要的。Foundation is the foundation of makeup. Powder foundation is the most common. It looks soft and natural when applied to the face. It is the choice of daily makeup. There are many types. Chinese patent CN104688590A discloses a moisturizing and breathable foundation. Chinese patent CN104069014A discloses A kind of foundation cream/liquid foundation and preparation method thereof with controllable discoloration etc. have been disclosed, but daily foundation also has a lot of problems in use, and conventional foundation will cause skin pores to be thick because of being applied on the face, produces acne At the same time, it is also very inconvenient in daily life. It often destroys its makeup because of some big activities, and it also needs to make up every day, which delays a lot of time. For this reason, it is very necessary to find a good foundation.
发明内容Contents of the invention
为了解决发明现有技术存在的上述问题，本提供了一种微注粉底，该粉底通过微注的方式而达到美肤的效果，而且还能收缩毛孔，节约大量的时间。In order to solve the above-mentioned problems in the prior art of the invention, this invention provides a micro-injection foundation, which achieves the effect of skin beautification through micro-injection, and can also shrink pores, saving a lot of time.
本发明可以通过以下技术方案来实现：The present invention can be realized through the following technical solutions:
一种微注粉底，其配方包括烟酰胺腺嘌呤二核苷酸4-8份、烟酰胺4-8份、氯化钙4-8份、氯化钠4-8份、辅酶R4-8份、色氨酸4-8份、抗坏血酸4-8份、视黄醇4-8份、色氨酸4-8份、抗老四胜肽4-8份、六胜肽4-8份、硫酸镁4-8份、磷酸二氢钠4-8份、玻尿酸4-8份、以及联邦食品药品及化妆品认可色料；A micro-injection foundation, the formula of which includes 4-8 parts of nicotinamide adenine dinucleotide, 4-8 parts of nicotinamide, 4-8 parts of calcium chloride, 4-8 parts of sodium chloride, and 4-8 parts of coenzyme R , 4-8 parts of tryptophan, 4-8 parts of ascorbic acid, 4-8 parts of retinol, 4-8 parts of tryptophan, 4-8 parts of anti-aging tetrapeptide, 4-8 parts of hexapeptide, sulfuric acid 4-8 parts of magnesium, 4-8 parts of sodium dihydrogen phosphate, 4-8 parts of hyaluronic acid, and colorants approved by the Federal Food, Drug and Cosmetics;
上述的微注粉底的配方中，所述的联邦食品药品及化妆品认可色料包括水、甘油、黑色氧化铁、黄色氧化铁、联邦食品药品及化妆品黄色色料、联邦食品药品及化妆品红黄色色料、二氧化钛；In the formula of the above-mentioned micro-injection foundation, the color materials approved by the Federal Food, Drug and Cosmetics include water, glycerin, black iron oxide, yellow iron oxide, yellow color of the Federal Food, Drug and Cosmetics, red yellow color of the Federal Food, Drug and Cosmetics material, titanium dioxide;
上述的微注粉底的配方，具体包括烟酰胺腺嘌呤二核苷酸5份、烟酰胺5份、氯化钙5份、氯化钠5份、辅酶5份、色氨酸5份、抗坏血酸5份、视黄醇6份、色氨酸6份、抗老四胜肽6份、六胜肽6份、硫酸镁6份、磷酸二氢钠6份、玻尿酸6份、以及水15份、甘油5份、黑色氧化铁1份、黄色氧化铁1份、联邦食品药品及化妆品5号或/和6号黄色色料0.4份、联邦食品药品及化妆品30号或/和40号红色色料0.4份、二氧化钛0.2份。The formula of the micro-injection foundation mentioned above specifically includes 5 parts of nicotinamide adenine dinucleotide, 5 parts of nicotinamide, 5 parts of calcium chloride, 5 parts of sodium chloride, 5 parts of coenzyme, 5 parts of tryptophan, and 5 parts of ascorbic acid. 6 parts, 6 parts of retinol, 6 parts of tryptophan, 6 parts of anti-aging tetrapeptide, 6 parts of hexapeptide, 6 parts of magnesium sulfate, 6 parts of sodium dihydrogen phosphate, 6 parts of hyaluronic acid, and 15 parts of water, glycerin 5 parts, 1 part of black iron oxide, 1 part of yellow iron oxide, 0.4 parts of Federal Food, Drug and Cosmetics No. 5 or/and No. 6 yellow colorant, 0.4 part of Federal Food, Drug and Cosmetics No. 30 or/and No. 40 red colorant , 0.2 parts of titanium dioxide.
上述的微注粉底，其制备方法包括：Above-mentioned micro-injection foundation, its preparation method comprises:
(1)、取烟酰胺腺嘌呤二核苷酸5g、烟酰胺5g、氯化钙5g、氯化钠5g、辅酶5g、色氨酸5g、抗坏血酸5g、色氨酸6g、抗老四胜肽6g、六胜肽6g、视黄醇6g、硫酸镁6g、磷酸二氢钠6g、玻尿酸6g研磨混合备用；(1) Take 5g of nicotinamide adenine dinucleotide, 5g of nicotinamide, 5g of calcium chloride, 5g of sodium chloride, 5g of coenzyme, 5g of tryptophan, 5g of ascorbic acid, 6g of tryptophan, and anti-aging tetrapeptide 6g, hexapeptide 6g, retinol 6g, magnesium sulfate 6g, sodium dihydrogen phosphate 6g, hyaluronic acid 6g, grind and mix for later use;
(2)、取水15g，甘油5g混合，加入黑色氧化铁1g、黄色氧化铁1g、联邦食品药品及化妆品5号和6号黄色色料0.4g、联邦食品药品及化妆品30号和40号红色色料0.4g、二氧化钛0.2g进行超声5分钟，溶液备用；(2), take 15g of water, mix 5g of glycerin, add 1g of black iron oxide, 1g of yellow iron oxide, 0.4g of federal food, drug and cosmetic No. 5 and No. 6 yellow pigments, federal food, drug and cosmetic No. 30 and No. 40 red color 0.4g of material and 0.2g of titanium dioxide were subjected to ultrasonication for 5 minutes, and the solution was set aside;
(3)、将(1)和(2)步中的进行混合于60～70℃水浴上搅拌至全溶，冷却至室温，混匀后用0.22μm滤膜过滤，于70-80℃的密闭条件下稳定2-4小时，然后在室温下密闭冷却，分瓶灌装，封口，灭菌,即得。(3) Mix the ingredients in (1) and (2) in a 60-70°C water bath and stir until fully dissolved, cool to room temperature, filter with a 0.22μm filter membrane after mixing, and place in a sealed container at 70-80°C It is stable for 2-4 hours under the same conditions, then airtightly cooled at room temperature, filled in separate bottles, sealed, sterilized, and obtained.
上述的微注粉底的制备方法中，所述稳定是在密闭的反应釜中进行。In the preparation method of the above-mentioned micro-injection foundation, the stabilization is carried out in a closed reaction kettle.
本发明的有益效果为：本发明提供了一种微注粉底，通过微注注射，不仅能够起到美容的作用，而且还能收缩毛孔，便于妆容的保持不被破坏。The beneficial effects of the present invention are as follows: the present invention provides a micro-injection foundation, through micro-injection injection, not only can play the role of beautification, but also can shrink pores, so that the makeup can be maintained without being damaged.
为使本发明的目的、技术方案和优点更加清楚，下面将对本发明的技术方案进行详细的描述。显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动的前提下所得到的所有其它实施方式，都属于本发明所保护的范围；In order to make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention will be described in detail below. Apparently, the described embodiments are only some of the embodiments of the present invention, but not all of them. Based on the embodiments of the present invention, all other implementations obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention;
根据本发明，人类的毛孔直径一般在100-200微米左右，平均粒径在毛孔直径附近的颗粒容易堵塞毛孔，因此本发明的粉底颗粒的平均粒径通过研磨溶解后小于人类毛孔直径，通过微注不会造成毛孔的堵塞；According to the present invention, the pore diameter of human beings is generally about 100-200 microns, and the particles with an average particle diameter near the pore diameter are easy to block the pores, so the average particle diameter of the foundation particles of the present invention is smaller than the human pore diameter after grinding and dissolving. Note that it will not cause clogging of pores;
根据本发明，通过微注粉底，可保持2周到4周，从而节约了大量的时间，由于其系皮下微注，不会造成伤害。According to the present invention, the micro-injection foundation can be kept for 2 to 4 weeks, thereby saving a lot of time, and because it is subcutaneous micro-injection, it will not cause damage.
根据本发明，选取5名18-38岁的毛孔粗大的女性，对其进行了3个月的微注粉底，结果发现，其皮肤毛孔有缩小的效果，说明本发明的粉底不仅能够长期使用，而且对毛孔收缩有一定的效果。According to the present invention, 5 18-38-year-old women with large pores were selected, and micro-injected foundation was carried out for 3 months. It was found that the pores of their skin had the effect of shrinking, indicating that the foundation of the present invention can not only be used for a long time, And it has a certain effect on shrinking pores.
实施例1、Embodiment 1,
处方：烟酰胺腺嘌呤二核苷酸5份、烟酰胺5份、氯化钙5份、氯化钠5份、辅酶5份、色氨酸5份、抗坏血酸5份、色氨酸6份、抗老四胜肽6份、六胜肽6份、视黄醇6份、硫酸镁6份、磷酸二氢钠6份、玻尿酸6份、以及水15份、甘油5份、黑色氧化铁1份、黄色氧化铁1份、联邦食品药品及化妆品5号和6号黄色色料0.4份、联邦食品药品及化妆品30号和40号红色色料0.4份、二氧化钛0.2份；Prescription: 5 parts of nicotinamide adenine dinucleotide, 5 parts of nicotinamide, 5 parts of calcium chloride, 5 parts of sodium chloride, 5 parts of coenzyme, 5 parts of tryptophan, 5 parts of ascorbic acid, 6 parts of tryptophan, 6 parts of anti-aging tetrapeptide, 6 parts of hexapeptide, 6 parts of retinol, 6 parts of magnesium sulfate, 6 parts of sodium dihydrogen phosphate, 6 parts of hyaluronic acid, 15 parts of water, 5 parts of glycerin, and 1 part of black iron oxide , 1 part of yellow iron oxide, 0.4 parts of federal food, drugs and cosmetics No. 5 and No. 6 yellow pigments, 0.4 parts of federal food, drugs and cosmetics No. 30 and No. 40 red pigments, and 0.2 parts of titanium dioxide;
制备方法：取烟酰胺腺嘌呤二核苷酸、烟酰胺、氯化钙、氯化钠、辅酶、色氨酸、抗坏血酸、色氨酸、抗老四胜肽、六胜肽、视黄醇、硫酸镁、磷酸二氢钠、玻尿酸研磨混合备用；取水，甘油混合，加入黑色氧化铁、黄色氧化铁、联邦食品药品及化妆品黄色色料、联邦食品药品及化妆品红黄色色料、二氧化钛进行超声5分钟，溶液备用；将上述的备用物进行混合于60～70℃水浴上搅拌至全溶，冷却至室温，混匀后用0.22μm滤膜过滤，于70-80℃的密闭条件下稳定2-4小时，然后在室温下密闭冷却，分瓶灌装，封口，灭菌,即得；Preparation method: take nicotinamide adenine dinucleotide, nicotinamide, calcium chloride, sodium chloride, coenzyme, tryptophan, ascorbic acid, tryptophan, anti-aging tetrapeptide, hexapeptide, retinol, Magnesium sulfate, sodium dihydrogen phosphate, and hyaluronic acid are ground and mixed for later use; water and glycerin are mixed, and black iron oxide, yellow iron oxide, federal food, drug and cosmetic yellow colorant, federal food drug and cosmetic red-yellow colorant, and titanium dioxide are added for ultrasonication 5 Minutes, the solution is ready for use; mix the above-mentioned spare parts in a 60-70 °C water bath and stir until completely dissolved, cool to room temperature, mix and filter with a 0.22 μm filter membrane, and stabilize the 2- 4 hours, then airtightly cool at room temperature, fill in separate bottles, seal, sterilize, and get ready;
使用方法：使用高精微注仪器(导入频率调至80赫斯)，导入皮肤，微注How to use: Use a high-precision micro-injection instrument (adjust the import frequency to 80 Hz), introduce into the skin, and micro-inject
针头必须与导入部位成90度直角；同时把微注粉底导入时，保证导入至表皮下0.2-0.3mm。The needle must be at a 90-degree right angle to the introduction site; at the same time, when introducing the micro-injection foundation, ensure that it is introduced 0.2-0.3mm below the epidermis.
实施例2、处方：烟酰胺腺嘌呤二核苷酸5份、烟酰胺4份、氯化钙6份、氯化钠5份、辅酶4份、色氨酸5份、抗坏血酸5份、色氨酸6份、抗老四胜肽5份、六胜肽7份、视黄醇4份、硫酸镁4份、磷酸二氢钠8份、玻尿酸6份、以及水15份、甘油5份、黑色氧化铁1份、黄色氧化铁1份、联邦食品药品及化妆品5号黄色色料0.4份、联邦食品药品及40号化妆品红色色料0.4份、二氧化钛0.2份；Example 2, prescription: 5 parts of nicotinamide adenine dinucleotide, 4 parts of nicotinamide, 6 parts of calcium chloride, 5 parts of sodium chloride, 4 parts of coenzyme, 5 parts of tryptophan, 5 parts of ascorbic acid, tryptophan 6 parts of acid, 5 parts of anti-aging tetrapeptide, 7 parts of hexapeptide, 4 parts of retinol, 4 parts of magnesium sulfate, 8 parts of sodium dihydrogen phosphate, 6 parts of hyaluronic acid, 15 parts of water, 5 parts of glycerin, black 1 part of iron oxide, 1 part of yellow iron oxide, 0.4 part of federal food, drug and cosmetic No. 5 yellow pigment, 0.4 part of federal food and drug and No. 40 cosmetic red pigment, 0.2 part of titanium dioxide;
制备方法：取烟酰胺腺嘌呤二核苷酸、烟酰胺、氯化钙、氯化钠、辅酶、色氨酸、抗坏血酸、色氨酸、抗老四胜肽、六胜肽、视黄醇、硫酸镁、磷酸二氢钠、玻尿酸研磨混合备用；取水，甘油混合，加入黑色氧化铁、黄色氧化铁、联邦食品药品及化妆品黄色色料、联邦食品药品及化妆品红黄色色料、二氧化钛进行超声5分钟，溶液备用；将上述的备用物进行混合于60～70℃水浴上搅拌至全溶，冷却至室温，混匀后用0.22μm滤膜过滤，于70-80℃的密闭条件下稳定2-4小时，然后在室温下密闭冷却，分瓶灌装，封口，灭菌,即得；Preparation method: take nicotinamide adenine dinucleotide, nicotinamide, calcium chloride, sodium chloride, coenzyme, tryptophan, ascorbic acid, tryptophan, anti-aging tetrapeptide, hexapeptide, retinol, Magnesium sulfate, sodium dihydrogen phosphate, and hyaluronic acid are ground and mixed for later use; water and glycerin are mixed, and black iron oxide, yellow iron oxide, federal food, drug and cosmetic yellow colorant, federal food drug and cosmetic red-yellow colorant, and titanium dioxide are added for ultrasonication 5 Minutes, the solution is ready for use; mix the above-mentioned spare parts in a 60-70 °C water bath and stir until completely dissolved, cool to room temperature, mix and filter with a 0.22 μm filter membrane, and stabilize the 2- 4 hours, then airtightly cool at room temperature, fill in separate bottles, seal, sterilize, and get ready;
使用方法：使用高精微注仪器(导入频率调至80赫斯)，导入皮肤，微注How to use: Use a high-precision micro-injection instrument (adjust the import frequency to 80 Hz), introduce into the skin, and micro-inject
针头必须与导入部位成90度直角；同时把微注粉底导入时，保证导入至表皮下0.2-0.3mm。The needle must be at a 90-degree right angle to the introduction site; at the same time, when introducing the micro-injection foundation, ensure that it is introduced 0.2-0.3mm below the epidermis.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108721160A (en) * | 2017-10-13 | 2018-11-02 | 广东意之趣科技有限公司 | A kind of foundation cream and preparation method thereof of the mud of coloured silk containing natural minerals |
| CN110934768A (en) * | 2019-12-25 | 2020-03-31 | 深圳市龙格生技术有限公司 | Nicotinamide ribose derivative cosmetic raw material and application thereof in cosmetics |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002102328A1 (en) * | 2001-06-18 | 2002-12-27 | Philippe Bellity | Sterile injectable composition for aesthetic and/or reparative uses |
| CN102379838A (en) * | 2011-11-02 | 2012-03-21 | 广州舒泰生物技术有限公司 | Method for preparing relaxing and face-cleansing cosmetics and application |
| CN202740625U (en) * | 2012-08-07 | 2013-02-20 | 王礼 | Handheld electric microneedle beautification guide-in instrument |
| KR20150110332A (en) * | 2014-03-20 | 2015-10-02 | (주)아모레퍼시픽 | Composition for maintaining effect of filler |
| US20150320907A1 (en) * | 2012-05-07 | 2015-11-12 | Rania Agha | Dermal filler composition |
-
2016
- 2016-03-02 CN CN201610117724.3A patent/CN105769603A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002102328A1 (en) * | 2001-06-18 | 2002-12-27 | Philippe Bellity | Sterile injectable composition for aesthetic and/or reparative uses |
| CN102379838A (en) * | 2011-11-02 | 2012-03-21 | 广州舒泰生物技术有限公司 | Method for preparing relaxing and face-cleansing cosmetics and application |
| US20150320907A1 (en) * | 2012-05-07 | 2015-11-12 | Rania Agha | Dermal filler composition |
| CN202740625U (en) * | 2012-08-07 | 2013-02-20 | 王礼 | Handheld electric microneedle beautification guide-in instrument |
| KR20150110332A (en) * | 2014-03-20 | 2015-10-02 | (주)아모레퍼시픽 | Composition for maintaining effect of filler |
Non-Patent Citations (10)
| Title |
|---|
| 《健康大讲堂》委员会: "《《本草纲目》秘方王》", 31 January 2013, 黑龙江科学技术出版社 * |
| 周德华: "《实用麻醉科药物手册》", 31 October 2000, 人民军医出版社 * |
| 德拉洛斯 等: "《功能性化妆品》", 30 November 2007, 人民军医出版社 * |
| 晋红中: "《美容皮肤科》", 30 April 2014, 中国医药科技出版社 * |
| 李虹: "《广东省医疗美容医师培训教材系列丛书.美容技术分册》", 30 November 2015, 人民军医出版社 * |
| 林海峰: "《健康一生》", 31 May 2005, 中国物资出版社 * |
| 柠檬的力量研究所: "《柠檬的力量》", 31 May 2010, 中国画报出版社 * |
| 陈吉生: "《新编临床药物学》", 31 August 2013, 中国中医药出版社 * |
| 顾奎琴: "《食疗美容手册》", 30 November 2001, 现代出版社 * |
| 黎建宏: "《新编药物手册》", 31 October 2005, 江西科学技术出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108721160A (en) * | 2017-10-13 | 2018-11-02 | 广东意之趣科技有限公司 | A kind of foundation cream and preparation method thereof of the mud of coloured silk containing natural minerals |
| CN110934768A (en) * | 2019-12-25 | 2020-03-31 | 深圳市龙格生技术有限公司 | Nicotinamide ribose derivative cosmetic raw material and application thereof in cosmetics |
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