CN105748179A - Personalized airway stent manufacturing technology - Google Patents

Abstract

The invention discloses a preparation technology of a personalized airway bracket. The personalized airway stent of the present invention uses CT images to reconstruct the stenosis model of the patient's airway, and expands the stenosis of the airway model by 20% to 40% in the three-dimensional numerical model reconstruction software, and then the processed airway The outermost wall of the tract model was expanded outward by 10% to form the outer wall of the stent. A three-dimensional numerical model of a personalized airway stent was designed using the above processing. Finally, the personalized airway stent model is imported into the 3D printer, and medical biomaterials such as silicone are injected to prepare a personalized stent that conforms to the patient's airway structure. The present invention carries out three-dimensional modeling and designs a personalized airway stent according to different patients' airway stenosis, which overcomes the shortcomings and defects that the existing commercial airway stents are difficult to fit the patient's airway and easily cause granulation tissue hyperplasia.

Description

Preparation technology of a personalized airway stent

technical field

The invention belongs to the field of human airway implant interventional medical devices, and in particular relates to a preparation technology of a personalized airway stent.

Background technique

In recent years, various benign and malignant diseases and airway diseases caused by trauma, tracheotomy or intubation have been increasing, such as airway stenosis, tracheal wall collapse, airway-esophageal or gastric remnant fistula, airway-thoracic fistula, etc. , airway stenosis and tracheal wall collapse are usually treated clinically with stent implantation, which can rapidly expand the airway and relieve dyspnea. Airway-esophagus or remnant gastric fistula, airway-thoracic fistula, etc. Stent implantation for closure. Since Trendelenburg and Bond placed T-shaped tubes for the treatment of airway stenosis in the 1890s, people have been working on the research of airway stents, and various materials have been used to design various airway stents. There are two main types of commonly used tracheal and bronchial stents: (1) Silicone tubular stents, including: Dumon stents, T-tube stents, Dynamic stents, etc.; (2) Metal mesh stents: including: Palmaz stents , Stecker stent, Ultrflex stent, domestic nickel-titanium memory alloy stent, Wall stent, Gianturco stent, etc., and these series of stents have more or less the following problems because they cannot completely conform to the airway structure: (1) they cannot completely conform to the airway structure. Attached to the tracheal wall. The cross-section of the human trachea is not completely circular, and the upper and lower sides are not generally thick, but the cross-section of the airway stents currently used in clinical practice is mostly circular, and the upper and lower thickness are generally thin, so there will be some gaps between the stent and the tracheal wall. Airway secretions are easy to store here, and then become a breeding place for bacteria, etc. At the same time, the airway stent is prone to displacement; (2) The force on the tracheal wall is uneven. The "stress-growth" relationship of the living soul in biomechanics shows that the structure, function and growth of living organisms at all levels are closely related to their mechanical environment (stress field), and the human airway stent is no exception. Clinical data show that in the later stage of stent implantation, granulation tends to grow in areas with greater stress on the tracheal wall, such as the two ends of the stent, resulting in restenosis of the lumen. If it is not treated in time, it may seriously endanger the life of the patient.

Therefore, it is imperative to explore personalized airway stents, and the results of the research will have important clinical value and social significance.

Contents of the invention

In order to overcome the shortcomings and defects that the existing commercial airway stents are difficult to fit the patient's airway and easily cause granulation tissue hyperplasia. The primary purpose of the present invention is to prepare a personalized airway stent.

The present invention firstly designs a personalized airway support based on the three-dimensional numerical model reconstruction software of medical images, and then uses a 3D printer to prepare a personalized airway support.

The above object of the present invention is achieved through the following technical solutions:

1) Obtain CT scan data of the narrow part of the patient's airway;

2) Reconstruct the three-dimensional numerical model of the narrow part of the patient's airway;

3) Design a three-dimensional numerical model of a personalized airway stent;

4) Input this model into the 3D printer to prepare a personalized airway stent.

Compared with existing commercial supports, the present invention has the following advantages:

1) Existing airway stents belong to mass production, because everyone's airway is unique. Therefore existing commercial stents are not suitable for every different patient. The personalized airway stent prepared by the present invention conforms to the airway structure and shape of the individual patient, can completely fit the patient's airway, and can further reduce the excessive hyperplasia of airway granulation tissue;

2) The present invention performs three-dimensional modeling according to different patients with different airway stenosis and properly handles it, so that the design of individualized airway stents is achieved;

3) The present invention only needs to obtain the CT scan data of the patient to design a complete personalized airway stent model conforming to the patient's airway structure.

Description of drawings

Fig. 1 is a three-dimensional numerical model of the reconstructed airway stenosis segment according to the present invention.

Fig. 2 is a three-dimensional numerical model of a personalized airway stent designed according to the airway stenosis of the present invention.

Fig. 3 is a cross-sectional view of the personalized airway stent designed according to the airway stenosis of the patient according to the present invention.

detailed description

The present invention will be described in further detail below in conjunction with the embodiments, but the embodiments of the present invention are not limited thereto.

Step 1: Obtain CT scan data of the narrow part of the patient's airway, and reconstruct a three-dimensional numerical model of the narrow part of the patient's airway;

Step 2: Smooth and trim the airway model, and expand the diameter of the stenosis by 20% to 40% in the three-dimensional numerical model reconstruction software;

Step 3: On this basis, extend the outermost wall of the airway by 10% as the outer wall of the numerical model of the airway stent, and automatically generate a three-dimensional numerical model of the personalized airway stent after the model is closed;

Step 4: Input the model designed in the previous step into the 3D printer, and add biomedical materials such as silicone for 3D printing, thereby preparing a personalized airway stent.

Claims (6)

1. the technology of preparing of a personalized airway stent, it is characterised in that: the three-dimensional numeric design based on the narrow air flue rebuild goes out individual character activating QI road support.

2. the technology of preparing of personalized airway stent according to claim 1, it is characterised in that: the model of designed personalized airway stent can import in 3D printer, adds the biomaterial for medical purpose such as silicone and prints.

3. the technology of preparing of personalized airway stent according to claim 1, it is characterised in that: described personalized airway stent, it is the CT scan data obtaining patient airway narrow, and utilizes these data to set up the Three-dimension Numerical Model of narrow airway portion.

4. the technology of preparing of personalized airway stent according to claim 3, it is characterised in that: the expanded in diameter 20%～40% in Three-dimension Numerical Model reconstruction software, to air flue model stenosis.

5. the technology of preparing of personalized airway stent according to claim 4, it is characterised in that: in Three-dimension Numerical Model reconstruction software, outermost for air flue model wall is outwards extended 10%.

6. the technology of preparing of personalized airway stent according to claim 5, it is characterised in that: in Three-dimension Numerical Model reconstruction software, the outside wall surface partly as airway stent numerical model of air flue model outward expansion 10%.