CN1056301C - 'Lanweiling' oral liquid for treating appendicitis - Google Patents
'Lanweiling' oral liquid for treating appendicitis Download PDFInfo
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- CN1056301C CN1056301C CN97107827A CN97107827A CN1056301C CN 1056301 C CN1056301 C CN 1056301C CN 97107827 A CN97107827 A CN 97107827A CN 97107827 A CN97107827 A CN 97107827A CN 1056301 C CN1056301 C CN 1056301C
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- lanweiling
- appendicitis
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- 239000007788 liquid Substances 0.000 title claims abstract description 28
- 206010003011 Appendicitis Diseases 0.000 title abstract description 11
- 241000218176 Corydalis Species 0.000 claims abstract description 5
- 241000628997 Flos Species 0.000 claims abstract description 5
- 235000014375 Curcuma Nutrition 0.000 claims abstract description 3
- 239000004480 active ingredient Substances 0.000 claims description 3
- 244000164439 Curcuma angustifolia Species 0.000 claims description 2
- 241000555682 Forsythia x intermedia Species 0.000 claims description 2
- 241000501098 Sargentodoxa Species 0.000 claims description 2
- 241000207929 Scutellaria Species 0.000 claims description 2
- 239000002994 raw material Substances 0.000 claims description 2
- 239000003814 drug Substances 0.000 abstract description 20
- 230000000694 effects Effects 0.000 abstract description 3
- 230000001737 promoting effect Effects 0.000 abstract description 3
- 230000017531 blood circulation Effects 0.000 abstract description 2
- 241000050051 Chelone glabra Species 0.000 abstract 1
- 244000247747 Coptis groenlandica Species 0.000 abstract 1
- 235000002991 Coptis groenlandica Nutrition 0.000 abstract 1
- 244000164480 Curcuma aromatica Species 0.000 abstract 1
- 244000148137 Patrinia villosa Species 0.000 abstract 1
- 235000019109 Patrinia villosa Nutrition 0.000 abstract 1
- 244000299790 Rheum rhabarbarum Species 0.000 abstract 1
- 235000009411 Rheum rhabarbarum Nutrition 0.000 abstract 1
- 240000001949 Taraxacum officinale Species 0.000 abstract 1
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 abstract 1
- 239000009910 sargent gloryvine Substances 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- 241000699670 Mus sp. Species 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 3
- 238000004821 distillation Methods 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 239000012567 medical material Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 238000010298 pulverizing process Methods 0.000 description 2
- 239000011550 stock solution Substances 0.000 description 2
- 241000283956 Manis Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241001057584 Myrrha Species 0.000 description 1
- 231100000215 acute (single dose) toxicity testing Toxicity 0.000 description 1
- 238000011047 acute toxicity test Methods 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 235000011194 food seasoning agent Nutrition 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 210000002216 heart Anatomy 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 231100000682 maximum tolerated dose Toxicity 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a Zeng's Lanweiling oral administration liquid for treating appendicitis. The present invention is characterized in that the effective components (by weight ratio) of the present invention are composed of 5 portions of traditional Chinese medicine crude flos lonicerae, 5 portions of forsythiae, 5 portions of dandelion, 5 portions of patrinia, 1 to 2 portions of cortex moutan, 1 to 2 portions of rhubarb, 3 to 5 portions of sargentgloryvine stem, 3 to 5 portions of baical skullcap root, 1 portion of coptis, 3 to 5 portions of red sange root, 3 portions of curcuma root, and 5 portions of corydalis tuber. The Zeng's Lanweiling oral administration liquid for treating appendicitis, which is supplied by the present invention, has the effects of heat clearing, toxic removal, smoothness, blood circulation activation, stasis dissipation, qi promoting and pain relief. The present invention can effectively cure acute appendicitis. The present invention can reduce the operation pain of a patient and can greatly save the outlay of the patient.
Description
The present invention relates to a kind of Chinese patent medicine.
Acute appendicitis is a kind of common surgical diseases.The normal surgical operation therapy that changes after acute appendicitis is made a definite diagnosis, patient should bear the misery of operation, and expense is also higher simultaneously, in the place of no surgical conditions such as rural area, also is easy to cause the delay of the state of an illness.If can utilize the Drug therapy acute appendicitis, then can address the above problem.The Chinese invention patent application discloses the typhlitic Chinese medicine for oral administration of a kind of radical cure for No. 95105963.7, this Chinese medicine is made up of six kinds of medicines such as Radix Et Rhizoma Rhei, Semen Persicae (parched), Spina Gleditsiae, Squama Manis (processed), Semen Coicis, Myrrha (parched), and it is said has effect preferably to treatment appendicitis.
The purpose of this invention is to provide another kind of novel appendicitis medicine (Ceng Shi ' Lanweiling ' oral liquid for treating appendicitis).
The present invention is the typhlitic oral liquid of a kind of treatment, and its active ingredient is to be made by the raw material of following weight portion: 5 parts of 5 parts of Flos Lonicerae, 5 parts of Fructus Forsythiaes, 5 parts of Herba Taraxacis, 5 parts of Herba Patriniae, 1~2 part of Cortex Moutan, 1~2 part of Radix Et Rhizoma Rhei, 3~5 parts of Caulis Sargentodoxaes, 3~5 parts of Radix Scutellariaes, 1 part of Rhizoma Coptidis, 3~5 parts of Radix Salviae Miltiorrhizae, 3 parts of Radix Curcumaes and Rhizoma Corydalis.In the present invention, usually can be by above-mentioned each medicament mixed is decocted, concentrates, bottles and make water preparation.In the finished product of making, except that containing above-mentioned active ingredient, can also increase sugared agent, in order to auxiliary compositions such as antiseptical antiseptic in order to seasoning.
Show that through practical application oral liquid provided by the invention has that heat-clearing and toxic substances removing, Tongli are captured, the effect of blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, can cure acute appendicitis effectively.During treatment, general medication 5~7 days, the healing expense is no more than 100 yuan of RMB, only occupies 1/10 of institute's surgical operation expense.Like this, both reduce the corrective surgery misery, saved its funds spending again greatly.
Content of the present invention further illustrates with the following Examples, but content of the present invention is not limited only to content related among the embodiment.
Embodiment 1:
Take the Chinese medicine crude drug by following prescription:
Flos Lonicerae 5kg, Fructus Forsythiae 5kg, Herba Taraxaci 5kg, Herba Patriniae 5kg, Cortex Moutan 2kg, Radix Et Rhizoma Rhei 1kg, Caulis Sargentodoxae 5kg, Radix Scutellariae 3kg, Rhizoma Coptidis 1kg, Radix Salviae Miltiorrhizae 4kg, Radix Curcumae 3kg, Rhizoma Corydalis 5kg.
Above-mentioned Chinese crude drug is cleaned, dries, be crushed to 20~50 orders again.Medical material after pulverizing is inserted in the pot, add water logging and cross powder, boiled 2 hours, leach medicinal liquid, discard medicinal residues.With filter medicinal liquid be concentrated into 1/2 of stock solution, add ethanol in 1: 1 ratio again, make the float in the medicinal liquid generate precipitation.Filter clear liquid, with the way of distillation ethanol in the clear liquid is reclaimed.The concentration of allotment clear liquid makes every milliliter of clear liquid contain crude drug in whole 1.5 grams, gets 29.3 liters of finished product medicinal liquids at last.
With pack into glass bottle and sterilize, seal of finished product medicinal liquid, promptly make the final finished of water preparation form.
Embodiment 2:
Take the Chinese medicine crude drug by following prescription:
Flos Lonicerae 5kg, Fructus Forsythiae 5kg, Herba Taraxaci 5kg, Herba Patriniae 5kg, Cortex Moutan 1kg, Radix Et Rhizoma Rhei 2kg, Caulis Sargentodoxae 3kg, Radix Scutellariae 5kg, Rhizoma Coptidis 1kg, Radix Salviae Miltiorrhizae 5kg, Radix Curcumae 3kg, Rhizoma Corydalis 5kg.
Similar with last example, the Chinese crude drug of taking is cleaned, is crushed to 20~50 orders again after the oven dry.Medical material after pulverizing is inserted in the pot, add water logging and cross powder, boiled 2 hours, leach medicinal liquid, discard medicinal residues.With filter medicinal liquid be concentrated into 1/2 of stock solution, add ethanol in 1: 1 ratio again, make float generate precipitation.Leach the clear liquid on medicinal liquid top, the ethanol in the clear liquid is reclaimed with the way of distillation.The concentration of allotment clear liquid makes every milliliter of clear liquid contain crude drug in whole 1.5 grams, gets 30 liters of finished product medicinal liquids at last.
With pack into glass bottle and sterilize, seal of finished product medicinal liquid, promptly make the final finished of water preparation form.
By Chengdu University of Traditional Chinese Medicine's Experimental Animal Center experimental determination, the oral liquid of producing in the foregoing description is studied through acute toxicity test in mice, the result shows to mice lavage with Cmax, maximum volume administration three times on the one and a twice-daily, observe that mice does not have death and other anomaly in 7 days, the maximum tolerated dose of this medicine is 434.3g (crude drug)/kg and 289.6 (crude drug)/kg, is respectively 144 times and 96 times of Coming-of-Age Day consumption.More than two treated animals, after administration is observed 7, mice is taken off vertebra and puts to death, dissect mice, the important internal organs of perusal mice comprise the heart, liver, spleen, lung, kidney etc., there is no obvious pathological change.Final conclusion: this oral liquid toxicity is very little, is safety.
Claims (1)
1, the typhlitic oral liquid of a kind of treatment is characterized in that its active ingredient is to be made by the raw material of following weight portion: 5 parts of 5 parts of Flos Lonicerae, 5 parts of Fructus Forsythiaes, 5 parts of Herba Taraxacis, 5 parts of Herba Patriniae, 1~2 part of Cortex Moutan, 1~2 part of Radix Et Rhizoma Rhei, 3~5 parts of Caulis Sargentodoxaes, 3~5 parts of Radix Scutellariaes, 1 part of Rhizoma Coptidis, 3~5 parts of Radix Salviae Miltiorrhizae, 3 parts of Radix Curcumaes and Rhizoma Corydalis.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN97107827A CN1056301C (en) | 1997-12-16 | 1997-12-16 | 'Lanweiling' oral liquid for treating appendicitis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN97107827A CN1056301C (en) | 1997-12-16 | 1997-12-16 | 'Lanweiling' oral liquid for treating appendicitis |
Publications (2)
Publication Number | Publication Date |
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CN1188658A CN1188658A (en) | 1998-07-29 |
CN1056301C true CN1056301C (en) | 2000-09-13 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN97107827A Expired - Fee Related CN1056301C (en) | 1997-12-16 | 1997-12-16 | 'Lanweiling' oral liquid for treating appendicitis |
Country Status (1)
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CN (1) | CN1056301C (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1094061C (en) * | 1999-12-24 | 2002-11-13 | 冯俊明 | Medicine for curing appendicitis and its preparing method |
CN100374144C (en) * | 2006-05-23 | 2008-03-12 | 冯传宝 | Chinese medicinal oral liquid for treating appendicitis and enteritis |
CN101530516B (en) * | 2009-04-22 | 2011-08-17 | 王永 | Chinese medicament for treating appendicitis |
CN104189433A (en) * | 2014-09-24 | 2014-12-10 | 吕建晓 | Traditional Chinese medicine preparation for chronic appendicitis and preparation method of traditional Chinese medicine preparation |
CN105412266A (en) * | 2015-12-21 | 2016-03-23 | 张敬 | Traditional Chinese medicine composition for treating child appendicitis |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1115669A (en) * | 1995-06-05 | 1996-01-31 | 张清智 | Orally-taken Chinese medicine for curing appendicitis |
CN1134831A (en) * | 1995-06-06 | 1996-11-06 | 谭少奇 | Composite pharmaceutics made of oldenlandia and usage thereof |
-
1997
- 1997-12-16 CN CN97107827A patent/CN1056301C/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1115669A (en) * | 1995-06-05 | 1996-01-31 | 张清智 | Orally-taken Chinese medicine for curing appendicitis |
CN1134831A (en) * | 1995-06-06 | 1996-11-06 | 谭少奇 | Composite pharmaceutics made of oldenlandia and usage thereof |
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Publication number | Publication date |
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CN1188658A (en) | 1998-07-29 |
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