CN105602730A - Phoebe zhennan essential oil and preparation method thereof - Google Patents

Abstract

The invention discloses a nanmu essential oil and a preparation method thereof, comprising the following steps: firstly, pretreating nanmu to obtain a nanmu pretreated material; secondly, adding the nanmu pretreated material to an extraction device; thirdly, The essential oil containing solvent is separated from the extraction device; the fourth step is to separate the essential oil from the solvent; the fifth step is to dehydrate the essential oil; For wood, the pretreatment is to dry naturally or dry the bark, trunk, root, treetop, branch, flower, fruit and other raw materials of Phoebe, and then sieve after crushing. The advantages of the present invention are: Phoebe essential oil has antibacterial and anti-inflammatory properties, anti-corrosion and anti-insect, can treat senile chronic bronchitis, local anesthesia, treat colitis, antitussive and expectorant, treat stomach disease, conjunctivitis, analgesia, expelling wind and dehumidification and other special effects ; The preparation method has a high extraction rate, is green and safe, and is simple to operate.

Description

Phoebe essential oil and preparation method thereof

technical field

The invention relates to the field of daily chemical industry, in particular to nanmu essential oil and a preparation method thereof.

Background technique

Phoebe in a broad sense includes Phoebe (formerly known as Zhennan, PhoebeNees) and Runnan (MachilusNees) and their related genera. Phoebe wood has fine structure, stable wood, beautiful texture and easy processing. It is an important building and furniture material in ancient my country. It was exclusively used by the royal family during the Ming and Qing Dynasties. Phoebe has a profound cultural background. From palaces to mausoleums, from seats to beds, as a carrier of Chinese culture, it reflects the royal culture of Chinese feudal society and the aesthetics of literati and officials, and embodies the essence of wood culture in architecture, furniture and artwork. . (The fragrance of nanmu is elegant and long,) Living in the elegant room decorated with nanmu for a long time, accompanied by nanmu furniture, smelling its delicate fragrance can prolong life and maintain health.

In recent years, nanmu has been rapidly promoted by the market. After 2013, the appreciation rate has surpassed that of Hainan huanghuali. At present, the market price is higher than that of traditional high-grade wood such as red rosewood. The so-called "Great Age Play Collection" is favored by many consumers due to its characteristics of anti-corrosion and insect resistance, unique material properties, delicate smell, and cool in winter and cool in summer. The market is booming in both sales and purchases. As a precious wood, Nanmu is not only used as furniture, but also important building sites and woodcarving materials in the past dynasties. Some important palace buildings in Ming and Qing Dynasties used Nanmu as beams, but in the modern processing and production process, a large number of processing corners are left behind. The raw materials and sawdust are not effectively utilized, but are incinerated or discarded. Since most of the nanmu species are national second-class protected plants and cannot be harvested at will, and the growth rate of nanmu is very slow, the price of nanmu after becoming useful is expensive. In view of this, how to find a method for preparing nanmu essential oil that can give full play to the advantages of nanmu wood and has a simple and convenient production process is an urgent industry hot issue.

In ancient China, nanmu was used as a good medicine for blindly dispelling diseases. Ancient medical books recorded "foot edema. Cut nanmu and paulownia wood and boil water to soak feet, and drink a little of this water. Do this every day until the disease is cured. Heart distension and abdominal pain, no vomiting and diarrhea. Take three or four liang of nanmu, add three liters of water, boil for three times, and take it with drink. The pus comes out of the ear. Burn the nanmu for preservation, grind it into powder and apply it to the ear" ("Compendium of Materia Medica", Li Shizhen); "The branches and leaves of nanmu are bitter and warm, Non-toxic, the main cholera, decoct it, the tree is tall and the leaves are like mulberry, and it comes out of the southern mountains. Guo Zhuer Yayun, Nan, big tree, leaves like mulberry" ("Zheng Lei Materia Medica", Tang Shenwei); "Nanpi Decoction , to treat cold stomach and vomiting against righteousness, take it with nanmu bark decoction soup" ("Children's Health General Micro-On Prescription"); Divide, the two medicines on the right are finely ground into powder, take a little of each, and put it in the ear" ("Taiping Shenghui Prescription", official revision book of the Northern Song Dynasty);

"To control cholera... Take the branches and leaves of nanmu. Decoct it and take it"; Three catties, two catties of nanmu, the right piece of medicine, finely file and evenly. Use half a catty per degree. Use three buckets of water. Fry until two buckets. Remove the water to see whether it is warm or cold. Drench and dip in a sheltered place" ("Puji Fang", Zhu Wei etc.); in summary, Phoebe is used as medicine, taken internally and externally, and can treat diseases such as stomach problems, cholera, cholera tendons, pus from ears (otitis media), beriberi. Although ancient books have recorded a large number of classic examples of Phoebe being used in medicine, the chemical composition and health-preserving medicinal principles of Phoebe have not been confirmed by modern medicine.

Although there are also some patents about wood essential oil and technology at present, such as steam distillation combined with supercritical CO2 extraction method for preparing cypress essential oil (application number: CN201210339865.1), cypress essential oil and cigarettes containing cypress essential oil (application number: CN201010044402.3 ), a production process and equipment for extracting rosewood essential oil from rosewood sawdust (application number: CN201510187394.0), a natural health-care essential oil of moringa (application number: CN201510256307.2), but about Phoebe essential oil and its preparation method Research papers and patent reports are basically blank. Phoebe is a precious resource, and its processing waste has not been effectively utilized. Although the above-mentioned method of extracting essential oils is mentioned, the process is complicated, the efficiency is average, and the safety needs to be improved. Moreover, the wood structure and composition of different tree species are different. Therefore, the above-mentioned method does not It is suitable for the extraction of nanmu essential oil. The present invention aims to explore a technology for efficiently extracting nanmu essential oil. This technology can not only make full use of wastes such as processing scraps and sawdust of nanmu wood, but also fully explore the medicinal and health value of material resources such as branches, leaves, bark, etc., and improve The economic value of Phoebe plantation process can also make full use of the health-preserving medicinal value of Phoebe by the present invention simultaneously.

Contents of the invention

The object of the present invention is to address the above problems and provide a process for extracting nanmu essential oil with high extraction rate, green and safe, and simple operation.

The invention provides a method for preparing nanmu essential oil, which mainly includes the following steps:

The first step is to pretreat nanmu to obtain nanmu pretreatment material;

In the second step, the nanmu pretreatment material and solvent are added to the ultrasonic treatment device;

In the third step, the raw material after ultrasonic treatment is transferred to the extraction device, and the essential oil containing solvent is separated from it;

The fourth step is to separate the essential oil from the solvent;

The fifth step, essential oil dehydration;

Further, in the first step, the raw material is the wood of Phoebe genus, Phoebe genus and its close relative species, and the pretreatment is to prepare the bark, trunk, root, treetop, branch, flower and fruit of Phoebe The raw materials are naturally air-dried or crushed after drying, and then sieved after crushing. The mesh size of the sieve is 4 to 100 mesh.

Furthermore, the extraction device in the third step is an organic solvent extraction device, or a water vapor extraction device;

Further, in the third step, the method used to separate the essential oil containing solvent is vacuum filtration, plate and frame filtration, pressure filtration, or condensation reflux;

Further, in the fourth step, the method for separating the essential oil from the solvent is vacuum distillation, gravity separation, or centrifugation;

Furthermore, in the fifth step, the essential oil is dehydrated by using anhydrous sodium sulfate dehydration, or dehydration by normal pressure and low temperature drying method.

The present invention also provides a method for preparing nanmu essential oil, which mainly includes the following steps:

In the first step, raw materials such as bark, trunk, root, treetop, branch, flower and fruit of Nanmu are naturally air-dried or dried, then crushed, and then sieved after crushing to obtain a pretreated material of Nanmu.

In the second step, the nanmu pretreatment material is added into the ultrasonic treatment device for ultrasonic treatment;

In the third step, the organic solvent and the nanmu slag are filtered by vacuum filtration and then transferred;

In the fourth step, the filtered filtrate is subjected to vacuum distillation to obtain a crude extract;

The fifth step is to remove water from the crude extract by passing it over anhydrous sodium sulfate, or dry it at low temperature to remove water;

Further, in the second step, the solvent is one or more of ethanol, ethyl acetate, acetone, ether; the amount of solvent added is 10-40ml/g nanmu pretreatment material; the extraction time is 3 -48h; Ultrasonic treatment time is 10-120min, temperature is 10-60℃, ultrasonic frequency is 20-80Hz;

Further, in the third step, the pore diameter of the filter under reduced pressure filtration is 0.2-0.8 μm;

Furthermore, in the fourth step, the pressure of vacuum concentration is 0.03-0.1MPa, and the temperature is 30-70°C;

Furthermore, in the fifth step, the dosage of the anhydrous sodium sulfate is 0.2-1g/ml crude extract; or adopt low temperature and normal pressure method to dry and dehydrate to obtain the crude extract of essential oil; the drying temperature is 0～ 5 ℃, the time is 5 ~ 100h;.

The present invention also provides a method for preparing essential oil, which mainly includes the following steps:

In the first step, raw materials such as bark, trunk, root, treetop, branch, flower and fruit of Nanmu are naturally air-dried or dried, then crushed, and then sieved after crushing to obtain a pretreated material of Nanmu.

In the second step, add nanmu pretreatment material to 0-20% NaCl aqueous solution for ultrasonic treatment

The third step is to use a steam extraction device to extract;

In the third step, the water vapor entrained with the extract is collected by condensation and reflux;

The fourth step is to separate by gravity separation or centrifugation;

The fifth step is to dehydrate the crude extract by perusing anhydrous sodium sulfate, or dehydrating by normal pressure and low temperature drying method;

Further, in the second step, the nanmu pretreatment material is added into the ultrasonic treatment device for ultrasonic treatment; the solvent is 0-20% NaCl aqueous solution; the solvent addition amount is 3-10ml/g nanmu pretreatment material ; Ultrasonic treatment time is 5-60min, temperature is 10-60℃, ultrasonic frequency is 20-80Hz;

Furthermore, in the third step, the water vapor device is used for extraction, and the extraction time is 5-10 hours;

Furthermore, in the fourth step, gravity separation or centrifugal separation is used for separation, the gravity separation method is left standing for 10-60 minutes, and the speed of centrifugal separation method is 1000-4000 RPM, and the time is 1-10 minutes;

Further, in the fifth step, the dosage of the anhydrous sodium sulfate is 0.2-1g/ml crude extract; or adopt the method of low temperature and normal pressure to dry and dehydrate, the drying temperature is 0-5°C, and the drying time is 5 ~100h.

The present invention also provides a kind of Phoebe essential oil, which is prepared by any one of the above three methods.

The beneficial effects of the present invention are: according to the main components of Phoebe essential oil β-cineole, guaiazene, d-junipene, γ-junipene, guaiacyl alcohol, agarwood helicol, caryophyllene oxide, α -Cubacene learned that Phoebe essential oil has antibacterial, anti-inflammatory, anti-corrosion and anti-insect properties. It can treat chronic bronchitis in the elderly, local anesthesia, colitis, cough and expectorant, stomach disease, conjunctivitis, analgesia, wind and dampness and other special effects .

detailed description

The present invention will be further described below in conjunction with embodiment:

Example 1

(1) Pretreatment: Air-dry the xylem of Phoebe zhennan, crush and sieve to a particle size of less than 10 mesh, soak in 95% ethanol for 36 hours;

(2) Ultrasonic treatment: take an appropriate amount of powder treated in step (1), immerse it in a solvent, and ultrasonically treat it at 30°C for 120 minutes;

(3) Filtration: the solution treated in step 2 is filtered under reduced pressure, and the filtered solution is transparent and clear without obvious impurities;

(4) Distillation under reduced pressure: Add the liquid obtained in step 3 into a rotary evaporator to carry out distillation under reduced pressure at a pressure of 0.06 MPa and a temperature of 40° C. to obtain a crude extract;

(5) Dehydration: The crude product is dried and dehydrated at low temperature and normal pressure at a temperature of 3° C. for 10 hours. After dehydration, the xylem essential oil of Phoebe zhennan is obtained.

The obtained xylem essential oil of Phoebe zhennan was analyzed by GC-MS. The essential oil is mainly terpenoids, and β-cineole can help to develop drugs for treating vascular diseases. Gastrointestinal motility; guaiazene has antibacterial, anti-inflammatory, and conjunctivitis-treating effects; d-juninene has analgesic, antibacterial, and anti-tumor effects; γ-juninene has expectorant effects; Asthma; agarwood helicol has a stabilizing effect; myrcene is widely used as an important intermediate in drug synthesis; caryophyllene oxide can treat skin mycosis, and it also has the functions of soothing the liver, analgesia, antibacterial and anti-inflammatory, expelling wind and dampness, and clearing away heat The effect of detoxification, diuresis and swelling; β-caryophyllene has a certain antiasthmatic effect, can treat chronic bronchitis in the elderly, has local anesthesia, colitis, antitussive and expectorant effects, and can also repel mosquitoes, anti-anxiety and depression, Analgesic, and has very good anti-ulcer and anti-inflammatory effects; α-Cubacene can be used as an antibacterial agent, diuretic, and sedative; Leaf alcohol is the main component of propolis, so the zhennan essential oil has good stability and antitussive and antiasthmatic effects, and can also be used to develop neurological drugs and antitussive and antiasthmatic drugs.

Example 2

(1) Pretreatment: Air-dry the bark of Phoebe zhennan, crush and sieve to a particle size of less than 20 mesh, soak in 95% ethanol for 36 hours;

(2) Ultrasonic treatment: take an appropriate amount of powder treated in step (1), immerse it in a solvent, and ultrasonically treat it at 30°C for 120 minutes;

(3) Filtration: the solution treated in step 2 is filtered under reduced pressure, and the filtered solution is transparent and clear without obvious impurities;

(4) Distillation under reduced pressure: Add the liquid obtained in step 3 into a rotary evaporator for distillation under reduced pressure at a pressure of 0.09 MPa and a temperature of 50° C. to obtain a crude extract;

(5) Dehydration: The crude product is dried and dehydrated at low temperature and normal pressure at a temperature of 3°C for 15 hours. After dehydration, it becomes Zhennan bark essential oil;

The obtained zhennan bark essential oil was analyzed by GC-MS, and its main components and pharmacology were the same as above, but the proportions of the main components were different.

Example 3

(1) Pretreatment: Air-dry the leaves of Phoebe zhennan, crush and sieve to a particle size of less than 10 mesh, soak in 95% ethanol for 36 hours;

(2) Ultrasonic treatment: take an appropriate amount of powder treated in step (1), immerse it in a solvent, and ultrasonically treat it at 30°C for 120 minutes;

(3) Filtration: the solution treated in step 2 is filtered under reduced pressure, and the filtered solution is transparent and clear without obvious impurities;

(4) Distillation under reduced pressure: put the liquid obtained in step 3 into a rotary evaporator to carry out distillation under reduced pressure at a pressure of 0.07 MPa and a temperature of 40° C. to obtain a crude extract;

(5) Dehydration: Dry and dehydrate the crude product at low temperature and normal pressure at a temperature of 5°C for 10 hours. After dehydration, it becomes the essential oil of Phoebe zhennan leaves;

The obtained zhennan leaf essential oil was analyzed by GC-MS, and its main components and pharmacology were the same as above, but the proportions of the main components were different.

Example 4

(1) Pretreatment: air-dry the root of Phoebe zhennan, crush and sieve it to a particle size of less than 80 mesh, soak it in 95% ethanol for 48 hours;

(2) Ultrasonic treatment: take an appropriate amount of powder treated in step (1), immerse it in a solvent, and ultrasonically treat it at 40°C for 120 minutes;

(3) Filtration: the solution treated in step 2 is filtered under reduced pressure, and the filtered solution is transparent and clear without obvious impurities;

(4) Distillation under reduced pressure: Add the liquid obtained in step 3 into a rotary evaporator to carry out distillation under reduced pressure at a pressure of 0.08 MPa and a temperature of 40° C. to obtain a crude extract;

(5) Dehydration: remove the water from the crude product sodium persulfate anhydrous, the temperature is 2°C, the time is 40h, after the water is removed, it is the essential oil of Zhennan tree root;

The obtained essential oil of Phoebe zhennan root was analyzed by GC-MS, and its main components and pharmacology were the same as above, but the proportions of main components were different.

Example 5

(1) Pretreatment: Air-dry the zhennan branches, crush and sieve to a particle size of 80 mesh, soak in 95% ethanol for 48 hours;

(2) Ultrasonic treatment: take an appropriate amount of powder treated in step (1), immerse it in a solvent, and ultrasonically treat it at 40°C for 120 minutes;

(3) Filtration: the solution treated in step 2 is filtered under reduced pressure, and the filtered solution is transparent and clear without obvious impurities;

(4) Distillation under reduced pressure: add the liquid obtained in step 3 into a rotary evaporator to carry out distillation under reduced pressure at a pressure of 0.09 MPa and a temperature of 40° C. to obtain a crude extract;

(5) Dehydration: remove the water from the crude product sodium persulfate anhydrous, the temperature is 2°C, the time is 40h, after the water is removed, it is the essential oil of zhennan tree;

The obtained essential oil of Phoebe zhennan was analyzed by GC-MS, and its main components and pharmacology are the same as above, but the proportions of main components are different.

Example 6

(1) Pretreatment: Air-dry the zhennan cloudy material, crush and sieve, and the particle size is 80 mesh;

(2) Steam distillation: add 10% NaCl aqueous solution to the pretreated powder in step (1) according to the solid-liquid ratio of 1:10, and extract with a steam extraction device for 6 hours to obtain a crude product;

(3) Dehydration: remove the water from the crude product sodium peroxysulfate, the temperature is 0°C, the time is 40h, after the water is removed, it is the essential oil of Phoebe zhennan;

GC-MS analysis was carried out on the obtained zhennan cloudy essential oil, and its main components and pharmacology were the same as above, but the proportions of the main components were different.

Example 7

(1) Pretreatment: Air-dry the trunk of Phoebe zhennan, crush and sieve, and the particle size is 120 mesh;

(2) Steam distillation: add 10% NaCl aqueous solution to the pretreated powder in step (1) according to the solid-liquid ratio of 1:8, and extract with a steam extraction device for 6 hours to obtain a crude product;

(3) Dehydration: remove the water from the crude product sodium persulfate anhydrous, the temperature is 0°C, the time is 40h, after the water is removed, it is the trunk essential oil of Phoebe zhennan;

The obtained Phoebe zhennan trunk was subjected to GC-MS analysis, and its main components and pharmacology were the same as above, but the proportions of the main components were different.

Example 8

(1) Pretreatment: Air-dry the zhennan branches, crush and sieve, and the particle size is 60 mesh;

(2) Steam distillation: add 10% NaCl aqueous solution to the pretreated powder in step (1) according to the solid-liquid ratio of 1:8, and extract with a steam extraction device for 6 hours to obtain a crude product;

(3) Dehydration: remove the water from the crude product sodium persulfate anhydrous, the temperature is 0°C, the time is 40h, after the water is removed, it is the essential oil of zhennan tree;

The obtained Phoebe zhennan branches were analyzed by GC-MS, and the main components and pharmacology were the same as above, but the proportions of the main components were different.

Example 9

(1) Pretreatment: air-dry the leaves of Phoebe zhennan, pulverize and sieve, and the particle size is 4 mesh;

(2) Steam distillation: add 10% NaCl aqueous solution to the pretreated powder in step (1) according to the solid-liquid ratio of 1:8, and extract with a steam extraction device for 6 hours to obtain a crude product;

(3) Dehydration: the crude product is dehydrated by sodium peranhydrous sulfate, the temperature is 0°C, and the time is 20 hours. After dehydration, it is the essential oil of zhennan leaves;

The obtained zhennan leaves were analyzed by GC-MS, and the main components and pharmacology were the same as above, but the proportions of the main components were different.

Example 10

(1) Pretreatment: Air-dry the bark of Phoebe zhennan, pulverize and sieve, and the particle size is 40 mesh;

(2) Steam distillation: add 10% NaCl aqueous solution to the pretreated powder in step (1) according to the solid-liquid ratio of 1:8, and extract with a steam extraction device for 6 hours to obtain a crude product;

(3) Dehydration: the crude product sodium peranhydrous sulfate is dehydrated, the temperature is 0° C., and the time is 40 hours. After dehydration, it is Zhennan bark essential oil;

The obtained zhennan bark was analyzed by GC-MS, and its main components and pharmacology were the same as above, but the proportions of the main components were different.

Example 11

(1) pretreatment: air-drying the trunk of Phoebe chinensis, pulverizing and sieving, the particle size is 80 mesh;

(2) Steam distillation: add 10% NaCl aqueous solution to the pretreated powder in step (1) according to the solid-liquid ratio of 1:8, and extract with a steam extraction device for 6 hours to obtain a crude product;

(3) Dehydration: remove the water from the crude product with peranhydrous sodium sulfate at a temperature of 2° C. for 30 hours.

GC-MS analysis was performed on the obtained essential oil of Phoebe chinensis trunk, and the main components of the essential oil were monoterpenes and sesquiterpenoids. It has the advantages of definite curative effect, mild side effects, and can significantly improve the quality of life of tumor patients; β-caryophyllene has antibacterial, local anesthesia, anti-inflammatory, mosquito repellent, anti-anxiety, anti-inhibitory, and cough-relieving effects; γ-cadinene has expectorant Guaiol has antitussive, expectorant, and bronchitis treatment effects; α-cadinol has a strong acaricidal activity; β-eudesmol can assist in the development of drugs for the treatment of vascular diseases, has the effects of invigorating the spleen, drying dampness, and resisting hypoxia. Can significantly promote gastrointestinal motility. Terpenoids are the most widely distributed and most diverse plant natural products in nature. They have important physiological and sociological functions and have been widely used in industrial and agricultural production, medicine and hygiene, spices and other fields. Element. Therefore, the essential oil of Phoebe chinensis has a certain medicinal value for health preservation, mainly for antitussive, expectorant, antibacterial, and anti-inflammatory effects.

Example 12

(1) Pretreatment: air-dry the leaves of Phoebe chinensis, pulverize and sieve, and the particle size is 10 mesh;

(2) Steam distillation: add 10% NaCl aqueous solution to the pretreated powder in step (1) according to the solid-liquid ratio of 1:10, and extract with a steam extraction device for 6 hours to obtain a crude product;

(3) Dehydration: The crude product is dried and dehydrated at low temperature and normal pressure, the temperature is 2°C, and the time is 30 hours. After dehydration, it is the essential oil of Phoebe chinensis leaves;

GC-MS analysis was carried out to the essential oil of the leaves of Phoebe chinensis, and its main components and pharmacology were the same as above, but the proportions of the main components were different.

Example 13

(1) pretreatment: air-dry the branches of Phoebe chinensis, pulverize and sieve, and the particle size is 60 mesh;

(2) Steam distillation: add 10% NaCl aqueous solution to the pretreated powder in step (1) according to the solid-liquid ratio of 1:12, and extract with a steam extraction device for 6 hours to obtain a crude product;

(3) Dehydration: The crude product is dried and dehydrated at low temperature and normal pressure, the temperature is 0°C, and the time is 40 hours. After dehydration, it is the essential oil of Phoebe twigs;

The obtained Phoebe twig essential oil was analyzed by GC-MS, and its main components and pharmacology were the same as above, but the proportions of the main components were different.

Example 14

(1) Pretreatment: air-dry the bark of Phoebe chinensis, crush and sieve, and the particle size is 80 mesh;

(2) Steam distillation: add 10% NaCl aqueous solution to the pretreated powder in step (1) according to the solid-liquid ratio of 1:10, and extract with a steam extraction device for 6 hours to obtain a crude product;

(3) Dehydration: The crude product is dried and dehydrated at low temperature and normal pressure, the temperature is 0°C, and the time is 40h. After dehydration, it is the bark essential oil of Phoebe chinensis;

The obtained Phoebe bark essential oil was analyzed by GC-MS, and its main components and pharmacology were the same as above, but the proportions of the main components were different.

Example 15

(1) pretreatment: air-dry the roots of Phoebe chinensis, pulverize and sieve, and the particle size is 100 mesh;

(2) Steam distillation: add 10% NaCl aqueous solution to the pretreated powder in step (1) according to the solid-liquid ratio of 1:12, and extract with a steam extraction device for 6 hours to obtain a crude product;

(3) Dehydration: The crude product is dried and dehydrated at low temperature and normal pressure at a temperature of 3° C. for 40 hours. After dehydration, it becomes the root essential oil of Phoebe chinensis;

GC-MS analysis was carried out to the essential oil of the obtained Phoebe chinensis root, and its main components and pharmacology were the same as above, but the proportions of the main components were different.

Example 16

(1) Pretreatment: Air-dry the trunk of Phoebe nannesis, pulverize and sieve, and the particle size is 100 mesh;

(2) Steam distillation: add 10% NaCl aqueous solution to the pretreated powder in step (1) according to the solid-liquid ratio of 1:10, and extract with a steam extraction device for 6 hours to obtain a crude product;

(3) Dehydration: The crude product is dried and dehydrated at low temperature and normal pressure at a temperature of 3° C. for 40 hours. After dehydration, it becomes the essential oil of Phoebe basilica.

Example 17

(1) Pretreatment: Air-dry the xylem of Phoebe nangifolia, crush and sieve, and the particle size is 100 mesh;

(2) Steam distillation: add 10% NaCl aqueous solution to the pretreated powder in step (1) according to the solid-liquid ratio of 1:10, and extract with a steam extraction device for 6 hours to obtain a crude product;

(3) Dehydration: The crude product is dried and dehydrated at low temperature and normal pressure at 2° C. for 30 hours. After dehydration, it becomes Phoebe xylem essential oil.

Example 18

(1) pretreatment: air-drying the trunk of Zinan, pulverized and sieved, and the particle size is 80 mesh;

(2) Steam distillation: add 10% NaCl aqueous solution to the pretreated powder in step (1) according to the solid-liquid ratio of 1:8, and extract with a steam extraction device for 6 hours to obtain a crude product;

(3) Dehydration: The crude product is dried and dehydrated at low temperature and normal pressure at a temperature of 0° C. for 40 hours. After dehydration, it becomes the essential oil of Phoebe chinensis.

Example 19

(1) Pretreatment: Air-dry the fruit of Zinan, pulverize and sieve, and the particle size is 60 mesh;

(2) Steam distillation: add 10% NaCl aqueous solution to the cinnamon fruit powder sieved in step 1 according to the ratio of material to liquid of 1:10, and extract with a steam extraction device for 6 hours to obtain a crude product;

(3) Dehydration: The crude product is dried and dehydrated at low temperature and normal pressure at a temperature of 5° C. for 30 hours. After dehydration, it becomes the essential oil of nannus fruit.

The basic principles and main features of the present invention and the advantages of the present invention have been shown and described above. Those skilled in the industry should understand that the present invention is not limited by the above-mentioned embodiments. What are described in the above-mentioned embodiments and the description only illustrate the principle of the present invention. Without departing from the spirit and scope of the present invention, the present invention will also have Variations and improvements are possible, which fall within the scope of the claimed invention. The protection scope of the present invention is defined by the appended claims and their equivalents.

Claims (4)

1. a method for preparing Phoebe essential oil, is characterized in that, comprises the following steps: The first step is to pretreat nanmu to obtain nanmu pretreatment material; In the second step, the nanmu pretreatment material and solvent are added to the ultrasonic treatment device; In the third step, the raw material after ultrasonic treatment is transferred to the extraction device, and the essential oil containing solvent is separated from it; The fourth step is to separate the essential oil from the solvent; The fifth step, essential oil dehydration; In the first step, the raw material is wood of Phoebe genus, Phoebe genus and its close relative species, and the pretreatment is to dry the bark, trunk, roots, treetops, branches, flowers, fruits and other raw materials of Phoebe chinensis naturally Or dried and pulverized, then sieved after pulverized, with a sieve mesh of 2 to 100 mesh; The extraction device in the third step is an organic solvent extraction device, or a water vapor extraction device; In the third step, the method used to separate the essential oil containing solvent is vacuum filtration, plate and frame filtration, pressure filtration or condensation reflux; In the fourth step, the method for separating the essential oil from the solvent is vacuum distillation, gravity separation, centrifugal separation; In the fifth step, the essential oil is dehydrated by anhydrous sodium sulfate, or dehydrated by normal pressure and low temperature drying. 2. the preparation method of a kind of Phoebe essential oil as claimed in claim 1, is characterized in that: In the second step, the nanmu pretreatment material is added into the ultrasonic treatment device for ultrasonic treatment; the solvent is one or more of ethanol, ethyl acetate, acetone, ether; the solvent addition amount is 10-40ml /g nanmu pretreatment material; the extraction time is 3-48h; the ultrasonic treatment time is 10-120min, the temperature is 10-60°C, and the ultrasonic frequency is 20-80Hz; In the third step, the organic solvent and Phoebe wood residue are filtered by vacuum filtration and then transferred; the filter pore diameter of vacuum filtration is 0.2-0.8 μm; In the fourth step, the filtered filtrate is subjected to vacuum distillation to obtain a crude extract; the pressure of vacuum concentration is 0.03-0.1MPa, and the temperature is 30-70°C; In the fifth step, the crude extract is dehydrated by anhydrous sodium sulfate; the dosage of the anhydrous sodium sulfate is 0.2-1g/ml crude extract; ～5℃, the time is 5～100h; 3. the preparation method of a kind of Phoebe essential oil as claimed in claim 1, is characterized in that: In the second step, the nanmu pretreatment material is added into the ultrasonic treatment device for ultrasonic treatment; the solvent is 0 to 20% NaCl aqueous solution; the solvent addition amount is 3 to 10ml/g nanmu pretreatment material; the ultrasonic treatment time 5~60min, temperature 10~60℃, ultrasonic frequency 20~80Hz; In the third step, extraction is performed using a steam extraction device; the extraction time is 5 to 10 hours; In the third step, the water vapor entrained with the extract is collected by condensation and reflux; In the fourth step, adopt gravity separation method or centrifugal separation method to separate, gravity separation method stands still for 10-60min, centrifugal separation method speed is 1000-4000RPM, time is 1-10min; In the fifth step, the crude extract is dehydrated by anhydrous sodium sulfate; the dosage of the anhydrous sodium sulfate is 0.2-1g/ml crude extract; 0～5℃, the time is 5～100h. 4. A nanmu essential oil is characterized in that: it can be prepared by any one of the three methods described in claim 1, 2, and 3.