CN105551358B - A kind of simulated eye - Google Patents

Abstract

The invention provides a simulated eye, which includes a transparent artificial cornea and a closed cylindrical shell. The artificial cornea is fixed on one end of the shell and the middle part is spherically protruding outward. The other end of the shell is fixed to the artificial cornea. A concave spherical artificial eye fundus, the outer wall of the shell is provided with an electrode layer, the inner wall of the shell is provided with a hydrophobic dielectric layer, and the middle part of the shell is fixed with an insulating layer that separates the electrode layer and the hydrophobic dielectric layer into two parts. The insulating ring divides the inner cavity of the shell into a front cavity, a middle cavity and a rear cavity. The middle cavity corresponds to the insulating ring, and the front cavity and the rear cavity correspond to the hydrophobic dielectric layers on both sides of the insulating ring. There is a conductive polar liquid, and an insulating non-polar liquid is set in the front cavity and the rear cavity. The polar liquid and the non-polar liquid have the same density, different refractive index and are incompatible with each other. The polar liquid is connected to the DC power supply. The positive pole, the electrode layer is connected to the negative pole of the DC power supply; the polar liquid is an aqueous solution containing salt, ethylenediaminetetraacetic acid and polyethylene glycol.

Description

a simulated eye

technical field

The invention relates to a human eye calibration model, in particular to a simulated eye.

Background technique

At present, the human eye diopter inspection instruments (such as refractometers and refractometers) produced by ophthalmic equipment manufacturers on the market all use their own human eye calibration models, and they are all non-adjustable static model eyes. There is no unified calibration in the industry in China In addition, the human eye calibration models of different manufacturers are different, resulting in different standards for the human eye diopter inspection instruments produced by different manufacturers. It is difficult for doctors to use inspection instruments from different manufacturers to check patients, which brings inconvenience.

In response to the above problems, the publication number is CN102831810A, and the publication date is December 19, 2012. The Chinese patent application titled "a calibration model for simulating human eyes" discloses a calibration model for simulating human eyes, including a transparent artificial cornea and Airtight cylindrical shell, the artificial cornea is fixed at one end of the shell and the middle part is spherically protruding outward, the other end of the shell is fixed with a concave spherical artificial fundus corresponding to the artificial cornea, and the outer wall of the shell is set There is an electrode layer, the inner wall of the housing is provided with a hydrophobic dielectric layer, and the middle part of the housing is fixed with an insulating ring that separates the electrode layer and the hydrophobic dielectric layer into two parts. The insulating ring divides the inner cavity of the housing into a front cavity, a The middle cavity and the rear cavity, the middle cavity corresponds to the insulating ring, the front cavity and the rear cavity respectively correspond to the hydrophobic dielectric layers on both sides of the insulating ring, the middle cavity is equipped with a conductive polar liquid, and the front cavity and the rear cavity are equipped with Insulating non-polar liquid, polar liquid and non-polar liquid have the same density, different refractive index and are immiscible with each other, the polar liquid is connected to the positive pole of the DC power supply, and the electrode layer is connected to the negative pole of the DC power supply. The simple voltage adjustment of the diopter of the simulated human eye calibration model can realize the adjustment of different refractive states of the simulated eye. Used in the ophthalmology teaching process, the model eye can easily simulate the normal eye, myopia, hyperopia and other states.

When implementing the above Chinese patent application, the applicant of the present application found that although the patent application realizes the adjustment of the diopter by means of voltage, the stability of the optical axis is not good.

Contents of the invention

In view of the above-mentioned defects in the prior art, the present invention provides a new simulated human eye, and the technical problem to be solved is to provide optical axis stability.

In order to solve the above problems, the technical solution adopted by the present invention is: a simulated eye, including a transparent artificial cornea and a closed cylindrical shell, the artificial cornea is fixed at one end of the shell and the middle part is spherically protruding outward, and the shell The other end of the housing is fixed with a concave spherical artificial fundus corresponding to the artificial cornea. The outer wall of the housing is provided with an electrode layer, the inner wall of the housing is provided with a hydrophobic dielectric layer, and the middle of the housing is fixed with an electrode layer and a hydrophobic dielectric layer. The dielectric layer is separated into two parts of the insulating ring. The insulating ring divides the inner cavity of the shell into a front cavity, a middle cavity and a rear cavity. The middle cavity corresponds to the insulating ring. Corresponding to the dielectric layer, there is a conductive polar liquid in the middle cavity, and an insulating non-polar liquid in the front cavity and the rear cavity. The polar liquid is connected to the positive pole of the DC power supply, and the electrode layer is connected to the negative pole of the DC power supply; the polar liquid is an aqueous solution containing salt, ethylenediaminetetraacetic acid and polyethylene glycol.

Preferably, the salt is one of NaCl, MgCl ₂ , CaCl ₂ , MnCl ₂ , FeCl ₂ . More preferably, the mass percentage of the salt is 3%-5%.

Preferably, the mass percent content of the ethylenediaminetetraacetic acid is 0.3%-0.8%.

Preferably, the polyethylene glycol is polyethylene glycol 2000. More preferably, the mass percentage of polyethylene glycol 2000 is 1%-3%.

Preferably, the non-polar liquid is monobromododecane.

Preferably, an elastic light-transmitting film is provided between the middle cavity and the front cavity and between the middle cavity and the rear cavity.

Preferably, the artificial cornea is glass, resin or plastic.

Preferably, a simulated fundus image is provided on the inner wall of the artificial fundus.

The beneficial effects of the present invention are: the present invention realizes the adjustment of different refractive states of the simulated eye through simple voltage adjustment, the structure of the model eye is consistent with the real human eye, and can provide a unified calibration reference for ophthalmic refractive diagnostic instruments, It is very suitable for use in ophthalmology teaching. The model eye can easily simulate normal eyes, myopia, hyperopia and other states. There are no moving parts, and it has good durability, large diopter adjustment range, strong light penetration ability, and low power consumption. Low, high precision and fast speed characteristics. Moreover, the invention has the advantages of simple structure, small volume, light weight, stable optical axis, continuous zooming, rapid response, high precision, convenient operation, easy processing and low cost.

The idea, specific structure and technical effects of the present invention will be further described below in conjunction with the accompanying drawings, so as to fully understand the purpose, features and effects of the present invention.

Description of drawings

Fig. 1 is a structural schematic diagram of a specific embodiment of the simulated human eye provided by the present invention.

In the figure, 1-artificial cornea, 2-housing, 3-artificial fundus, 4-electrode layer, 5-hydrophobic dielectric layer, 6-insulating ring, 7-DC power supply, 8-anterior cavity, 9-middle cavity, 10-rear cavity, 11-translucent film.

a-upper contact angle between polar liquid and hydrophobic dielectric layer; β-lower contact angle between polar liquid and hydrophobic dielectric layer.

Detailed ways

Fig. 1 shows the structure of a simulated human eye provided by the prior art and the present invention.

As shown in Figure 1, the simulated human eye includes a transparent artificial cornea 1 and a closed cylindrical shell 2, the artificial cornea 1 is fixed on one end of the shell 2 and the middle part is spherically convex outward, the other end of the shell 2 Fix the concave spherical artificial eye fundus 3 corresponding to the artificial cornea 1, the outer wall of the housing 2 is provided with an electrode layer 4, the inner wall of the housing 2 is provided with a hydrophobic dielectric layer 5, and the middle part of the housing 2 is fixed with a The electrode layer 4 and the hydrophobic dielectric layer 5 are separated into two parts of the insulating ring 6. The insulating ring 6 divides the inner cavity of the housing 2 into a front cavity 8, a middle cavity 9 and a rear cavity 10. The middle cavity 9 corresponds to the insulating ring 6. , the front cavity 8 and the rear cavity 10 correspond to the hydrophobic dielectric layer 5 on both sides of the insulating ring 6 respectively, the middle cavity 9 is provided with a conductive polar liquid, and the front cavity 8 and the rear cavity 10 are provided with an insulating non-polar liquid. Liquid, the polar liquid and the non-polar liquid have the same density, different refractive index and are immiscible with each other, the polar liquid is connected to the positive pole of the DC power supply 7 , and the electrode layer 4 is connected to the negative pole of the DC power supply 7 . In addition, an elastic transparent film 11 is provided between the middle chamber 9 and the front chamber 8 and between the middle chamber and the rear chamber 10 . The elastic light-transmitting film 11 can avoid layer confusion between non-phase liquids, and also facilitate filling different liquids into different chambers. The artificial cornea 1 is glass, resin or plastic. Low cost, good light transmittance, easy to process. A simulated fundus image is provided on the inner wall of the artificial fundus 3 . Use fundus imaging equipment (such as fundus camera, ophthalmoscope, etc.) to observe the fundus image of the model eye, and compare the effects of different refractive states on the fundus imaging equipment. In this simulated human eye, bromododecane is used as the non-polar liquid, and its refractive index is n1=1.45; the polar liquid is sodium chloride aqueous solution, and its refractive index is n2=1.3398;

The above simulated human eyes can adjust the diopter through voltage. The principle is: since the polar liquid and the non-polar liquid have the same density, the interface between the polar liquid and the non-polar liquid can maintain a spherical shape in any direction, which is convenient for accurate Controlling the diopter of the simulated eye and changing the voltage applied between the polar liquid and the electrode layer can effectively change the interfacial tension between the polar liquid and the hydrophobic dielectric layer, thereby changing the relationship between the polar liquid and the hydrophobic dielectric layer. The change of the contact angle determines the curvature of the spherical interface between the polar liquid and the non-polar liquid, thus changing the diopter of the simulated eye.

The applicant found in implementing the simulated eye shown in Figure 1 that the stability of the optical axis of the simulated eye is not good, that is to say, the upper contact angle a between the polar liquid and the hydrophobic dielectric layer is relatively smaller than that between the polar liquid and the hydrophobic dielectric layer. There is a certain difference in the lower contact angle β between the dielectric layers. The shape of the lens surface changes under the action of voltage. Only by stabilizing the optical axis of the lens can the imaging not be affected during the zooming process. The solid lens can adjust the optical axis of the lens well through the mechanical part, but the liquid lens cannot adjust the optical axis in this way. If the lens surface of the liquid lens changes, the friction between the liquid and the container will increase, and at the same time The lens surface is likely to become asymmetrical, making the optical axis change and affecting imaging.

The applicant unexpectedly found in experiments that adding EDTA and polyethylene glycol to conventional saline solution can greatly increase the stability of the optical axis.

Embodiment one

The simulated eye shown in Figure 1 is used, wherein the inner diameter of the cylindrical shell is 7mm, the length is 7.5mm, the radius of curvature of the artificial cornea and the artificial eye fundus is 9.5mm, the thickness of the insulating ring is 1mm, and the insulating ring is close to the artificial cornea The distance between one side of the insulating ring and the inner surface of the artificial cornea is 2.5 mm, and the distance between the side of the insulating ring close to the artificial eye fundus and the inner surface of the artificial eye fundus is 3.5 mm. The artificial cornea is made of glass, the insulating ring is made of conventional plastic, and the material of the hydrophobic dielectric layer is parylene. The non-polar liquid is monobromododecane, and the polar liquid is 3% by mass sodium chloride aqueous solution. The interface between the non-polar liquid and the polar liquid is near the edge of the insulating ring. The entire simulated eye is placed horizontally. Different voltages were applied to test the difference between the upper contact angle a between the polar liquid and the hydrophobic dielectric layer and the lower contact angle β between the polar liquid and the hydrophobic dielectric layer, as shown in Table 1.

Table 1

Applied voltage 20v 30v 40v 50v 60v Absolute value of a-β 0.5 1.2 degrees 3.4 degrees 5.1 degrees 7.2 degrees

From the data in this table, it can be seen that as the applied voltage increases, the upper contact angle a between the polar liquid and the hydrophobic dielectric layer is relative to the lower contact angle β between the polar liquid and the hydrophobic dielectric layer The difference of , that is to say, the deviation of the optical axis relative to the horizontal line is getting larger and larger.

Embodiment two

The simulated eye shown in Figure 1 is used, wherein the inner diameter of the cylindrical shell is 7mm, the length is 7.5mm, the radius of curvature of the artificial cornea and the artificial eye fundus is 9.5mm, the thickness of the insulating ring is 1mm, and the insulating ring is close to the artificial cornea The distance between one side of the insulating ring and the inner surface of the artificial cornea is 2.5 mm, and the distance between the side of the insulating ring close to the artificial eye fundus and the inner surface of the artificial eye fundus is 3.5 mm. The artificial cornea is made of glass, the insulating ring is made of conventional plastic, and the material of the hydrophobic dielectric layer is parylene. The non-polar liquid adopts monobromododecane, and the polar liquid is an aqueous solution containing sodium chloride, ethylenediaminetetraacetic acid and polyethylene glycol 2000, wherein the mass percentage of sodium chloride is 3%, and the The mass percent content of diaminetetraacetic acid is 0.3%, and the mass percent content of polyethylene glycol 2000 is 1%. The interface between the non-polar liquid and the polar liquid is near the edge of the insulating ring. The entire simulated eye is placed horizontally. Different voltages were applied to test the difference between the upper contact angle a between the polar liquid and the hydrophobic dielectric layer and the lower contact angle β between the polar liquid and the hydrophobic dielectric layer, as shown in Table 2.

Table 2

Applied voltage 20v 30v 40v 50v 60v Absolute value of a-β 0.2 0.4 degrees 0.8 degrees 1.4 degrees 2.1 degrees

From the table data, it can be seen that with the increase of the applied voltage, although the upper contact angle a between the polar liquid and the hydrophobic dielectric layer is relative to the lower contact angle between the polar liquid and the hydrophobic dielectric layer The difference of β is getting bigger and bigger, but compared with the difference in Table 1, there is a big improvement.

Embodiment three

The simulated eye shown in Figure 1 is adopted, wherein the inner diameter of the cylindrical shell is 6.5 mm, the length is 7 mm, the radius of curvature of the artificial cornea and the artificial eye fundus is 9 mm, the thickness of the insulating ring is 1 mm, and the insulating ring is close to the artificial cornea. The distance from one side to the inner surface of the artificial cornea is 2.5 mm, and the distance from the side of the insulating ring close to the artificial eye fundus to the inner surface of the artificial eye fundus is 3 mm. The artificial cornea is made of glass, the insulating ring is made of conventional plastic, and the material of the hydrophobic dielectric layer is parylene. The non-polar liquid adopts bromododecane, and the polar liquid is an aqueous solution containing magnesium chloride, ethylenediaminetetraacetic acid and polyethylene glycol 2000, wherein the mass percentage of magnesium chloride is 5%, and the ethylenediaminetetraacetic acid The mass percentage content of polyethylene glycol 2000 is 0.8%, and the mass percentage content of polyethylene glycol 2000 is 3%. The interface between the non-polar liquid and the polar liquid is near the edge of the insulating ring. The entire simulated eye is placed horizontally. Different voltages were applied to test the difference between the upper contact angle a between the polar liquid and the hydrophobic dielectric layer and the lower contact angle β between the polar liquid and the hydrophobic dielectric layer, as shown in Table 3.

table 3

Applied voltage 20v 30v 40v 50v 60v Absolute value of a-β 0.2 0.3 degrees 0.7 degrees 1.2 degrees 1.8 degrees

From the table data, it can be seen that with the increase of the applied voltage, although the upper contact angle a between the polar liquid and the hydrophobic dielectric layer is relative to the lower contact angle between the polar liquid and the hydrophobic dielectric layer The difference of β is getting bigger and bigger, but relative to the difference of Table 1 in Example 1, there is a big improvement. Compared with Table 2 in Example 2, the composition of the salt is changed from sodium chloride to magnesium chloride, the percentage of each component of the polar liquid has been increased, and the stability of the optical axis has been improved to a certain extent.

Embodiment Four

The simulated eye shown in Figure 1 is used, wherein the inner diameter of the cylindrical shell is 7mm, the length is 7.5mm, the radius of curvature of the artificial cornea and the artificial eye fundus is 9.5mm, the thickness of the insulating ring is 1mm, and the insulating ring is close to the artificial cornea The distance between one side of the insulating ring and the inner surface of the artificial cornea is 2.5 mm, and the distance between the side of the insulating ring close to the artificial eye fundus and the inner surface of the artificial eye fundus is 3.5 mm. The artificial cornea is made of glass, the insulating ring is made of conventional plastic, and the material of the hydrophobic dielectric layer is parylene. The non-polar liquid adopts bromododecane, and the polar liquid is an aqueous solution containing magnesium chloride, ethylenediaminetetraacetic acid and polyethylene glycol 2000, wherein the mass percentage of magnesium chloride is 6%, ethylenediaminetetraacetic acid The mass percentage content of polyethylene glycol 2000 is 1%, and the mass percentage content of polyethylene glycol 2000 is 4%. The interface between the non-polar liquid and the polar liquid is near the edge of the insulating ring. The entire simulated eye is placed horizontally. Different voltages were applied to test the difference between the upper contact angle a between the polar liquid and the hydrophobic dielectric layer and the lower contact angle β between the polar liquid and the hydrophobic dielectric layer, as shown in Table 4.

Table 4

Applied voltage 20v 30v 40v 50v 60v Absolute value of a-β 0.4 0.8 degrees 1.6 degrees 2.2 degrees 2.8 degrees

It can be seen from the data in this table that as the applied voltage increases, although the upper contact angle a between the polar liquid and the hydrophobic dielectric layer is relative to the lower contact angle between the polar liquid and the hydrophobic dielectric layer The difference of β is getting bigger and bigger, but relative to the difference of Table 1 in Example 1, there is a big improvement. Compared with Table 3 in Example 3, the percentage content of each component of the polar liquid is further increased, but the stability of the optical axis is decreased instead.

The preferred specific embodiments of the present invention have been described in detail above. It should be understood that those skilled in the art can make many modifications and changes according to the concept of the present invention without creative efforts. Therefore, all technical solutions that can be obtained by those skilled in the art based on the concept of the present invention through logical analysis, reasoning or limited experiments on the basis of the prior art shall be within the scope of protection defined by the claims.

Claims (4)

1. a kind of simulated eye, including transparent artificial cornea and closed tubular shell, artificial cornea are fixed on one end of shell And spherical protrusion, the other end of shell fix the artificial eye of the dome shape in indent corresponding with artificial cornea outward at middle part The outer wall at bottom, shell is equipped with electrode layer, and the inner wall of shell is equipped with hydrophobic dielectric layer, and shell is fixedly arranged in the middle of electrode layer and dredges Water dielectric layer is isolated into two-part dead ring, and the inner cavity of shell is divided into ante-chamber, lumen and back cavity, lumen and insulation by dead ring Ring corresponds to, and ante-chamber and back cavity are corresponding with the hydrophobic dielectric layer of dead ring both sides respectively, and conductive polar liquid is equipped in lumen, preceding The nonpolar liquid of insulation is equipped in chamber and back cavity, polar liquid is identical as the density of nonpolar liquid, refractive index is different and mutual Immiscible, polar liquid is connected to the anode of DC power supply, and electrode layer is connected to the cathode of DC power supply；

It is characterized in that, the polar liquid is the aqueous solution containing salt, ethylenediamine tetra-acetic acid and polyethylene glycol, the salt is NaCl、MgCl₂、CaCl₂、MnCl₂、FeCl₂In one kind；The polyethylene glycol is polyethylene glycol 2000；The quality hundred of the salt It is 3% to divide content, and the mass percentage of the ethylenediamine tetra-acetic acid is 0.3%, the quality percentage of the polyethylene glycol 2000 Content is 1%；Or the mass percentage of the salt is 5%, the mass percentage of the ethylenediamine tetra-acetic acid is 0.8%, the mass percentage of the polyethylene glycol 2000 is 3%；The nonpolar liquid is a bromododecane.

2. simulated eye according to claim 1, which is characterized in that set between lumen and ante-chamber and between lumen and back cavity Flexible light-transmissive film.

3. simulated eye according to claim 1, which is characterized in that artificial cornea is glass, resin or plastics.

4. simulated eye according to claim 1, which is characterized in that the inner wall at artificial eye bottom is equipped with the eyeground figure of emulation Picture.